Biopharmaceutical degerming and filtering device

Abstract

The utility model relates to the technical field of degerming and filtering, and discloses a degerming and filtering device for biopharmacy, the top of a shell is communicated with a feeding pipe for filling biopharmacy raw materials, and the top of the feeding pipe is in threaded connection with a cover plate; a connecting frame is fixed in the shell, a filtering hopper for filtering biopharmaceutical raw materials is fixed to the bottom of the connecting frame, a steam generator for conducting high-temperature sterilization on the biopharmaceutical raw materials is installed on the top of the inner wall of the shell, a rotating shaft and a supporting frame are driven by a gear motor to rotate, and a sliding plate is pushed to be attached to the inner side wall of a sliding groove under the elastic force of an elastic piece; the scraping plate is arranged on the inner wall side of the filter hopper, so that the residual biological medicine liquid raw materials on the side wall and the bottom of the filter hopper are scraped, and the biological medicine liquid raw materials are prevented from being left on the inner wall side of the filter hopper after being filtered; biological medicine liquid raw materials can be effectively prevented from remaining on the inner wall side of the filtering hopper after being filtered, and pollutant residues can be reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of sterilization and filtration, in particular to a biopharmaceutical sterilization and filtration device. Background Art

[0002] Biopharmaceuticals refer to a class of products used for prevention, treatment and diagnosis that are manufactured from organisms, biological tissues, cells, organs, body fluids, etc. using the research results of microbiology, biology, medicine, biochemistry, biotechnology, pharmacy and other scientific principles and methods.

[0003] In a Chinese patent with the authorization announcement number CN215975384U, a biopharmaceutical sterilization filtration device is disclosed, including a device housing, a filtering mechanism is arranged inside the device housing, a sterilization mechanism is arranged inside the filtering mechanism, and the filtering mechanism includes a mounting ring fixedly connected to the top of the device housing. The biopharmaceutical sterilization filtration device is provided with a filtering mechanism. After completing the high-temperature disinfection and sterilization treatment, the user starts the stepper motor to drive the driving gear to rotate, and the driving gear then drives the synchronous gear ring to rotate, thereby realizing the rotation of the closed bucket, thereby converting the filtering bucket to a filtering state. When the filtering bucket and the closed bucket are in the filtering state, the filtered medicine passes through the double filtration of the through hole and the filter net at the filtering hole, and enters the receiving bucket after filtration. The device housing and the receiving bucket are provided with a sliding door at the corresponding position, and the receiving bucket can be taken out later to carry out subsequent treatment of the filtered medicine.

[0004] The above patent has the following defects: after the liquid raw materials of biopharmaceuticals are sterilized and filtered inside the filter bucket, due to the viscosity and surface tension of the physical properties of the liquid raw materials of biopharmaceuticals, part of the liquid raw materials of biopharmaceuticals will remain on the inner wall surface of the filter bucket, resulting in a decrease in the purity of the subsequent production environment of the liquid raw materials of biopharmaceuticals. For this reason, a biopharmaceutical sterilization and filtration device is proposed. Utility Model Content

[0005] The purpose of the utility model is to provide a biopharmaceutical sterilization and filtration device to solve the problem proposed in the above background technology that after the biopharmaceutical liquid raw materials are sterilized and filtered inside the filter bucket, part of the biopharmaceutical liquid raw materials will remain on the inner wall surface of the filter bucket due to the viscosity and surface tension of the physical properties of the biopharmaceutical liquid raw materials, resulting in reduced purity of the subsequent production environment of the biopharmaceutical liquid raw materials.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a biopharmaceutical sterilization and filtration device, comprising a shell, the top of which is connected to a feeding pipe for filling biopharmaceutical raw materials, and the top of the feeding pipe is threadedly connected to a cover plate;

[0007] A connecting frame is fixed inside the shell, a filter bucket for filtering biopharmaceutical raw materials is fixed at the bottom of the connecting frame, and a steam generator for high-temperature sterilization of biopharmaceutical raw materials is installed on the top of the inner wall of the shell;

[0008] A reduction motor is fixed at the center of the top of the shell, a rotating shaft is fixed to the output shaft end of the reduction motor, and a scraping component for scraping residual liquid on the inner wall of the filter bucket is arranged on one side of the rotating shaft.

[0009] Preferably, a material receiving hopper is inserted into one side of the bottom of the shell, and the material receiving hopper is located at the lower side of the filter hopper.

[0010] Preferably, the scraping assembly comprises a support frame, two fixing frames are fixed on one side of the support frame, and a slide groove is provided inside the fixing frame.

[0011] Preferably, a slide plate is slidably connected to the inner side of the slide groove, and a scraper plate is fixed to one side of the slide plate and seamlessly penetrates one side of the fixing frame.

[0012] Preferably, the outer side of the scraper is slidably connected to the inner wall of the filter bucket, and a spring piece is connected between one side of the slide plate and the inner wall of the slide groove.

[0013] Preferably, one side of the two support frames is fixed to the outer side of the rotating shaft.

[0014] Preferably, the outer side of the rotating shaft is rotatably connected to the top center of the shell through a sealed bearing, and the shape of the rotating shaft is a cylinder.

[0015] Compared with the prior art, the utility model adopts the above technical solution and has the following technical effects:

[0016] 1. The steam generator generates high-temperature steam to sterilize the biopharmaceutical liquid raw materials. At the same time, the filter bucket filters the biopharmaceutical liquid raw materials inside it. The filtered biopharmaceutical liquid raw materials drip into the receiving hopper. When the receiving hopper is full of filtered biopharmaceutical liquid raw materials, the receiving hopper can be taken out. The use of high-temperature steam to sterilize the biopharmaceutical liquid raw materials can effectively kill various microorganisms and ensure the sterility of the product in accordance with the high standards of biopharmaceuticals. The filter bucket can effectively remove solid impurities and particles in the liquid raw materials to ensure the purity of the final product.

[0017] 2. By using a support frame instead of a stirring rod, stirring the biopharmaceutical liquid raw materials can prevent them from settling or forming an uneven suspension, thereby ensuring that the liquid can pass through the filter bucket evenly and quickly during the filtration process, improving the filtration efficiency. At the same time, stirring helps prevent particles from accumulating on the filter bucket, reducing the risk of clogging and keeping the filter bucket unobstructed.

[0018] 3. The reduction motor drives the rotating shaft and the support frame to rotate. Under the elastic force of the spring piece, the slide plate is pushed to fit the inner wall of the slide groove, so that the scraper fits the inner wall of the filter bucket, and the residual biopharmaceutical liquid raw materials on the side wall and bottom of the filter bucket are scraped off to avoid the biopharmaceutical liquid raw materials remaining on the inner wall of the filter bucket after filtration. By scraping off the residues on the inner wall of the filter bucket, it can effectively avoid the biopharmaceutical liquid raw materials remaining on the inner wall of the filter bucket after filtration, which helps to reduce the residual pollutants and ensure the purity and safety of subsequent production links. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0020] Figure 1 This is a schematic diagram of the appearance structure of the utility model;

[0021] Figure 2 This is a schematic structural diagram of a steam generator of the utility model;

[0022] Figure 3 This is a schematic diagram of the main cross-sectional structure of the filter bucket of the utility model;

[0023] Figure 4 This is a schematic diagram of the structure of the first filter bucket of the utility model;

[0024] Figure 5 This is a schematic diagram of the structure of the second filter bucket of the utility model;

[0025] Figure 6 It is a schematic diagram of the main cross-sectional structure of the fixing frame of the utility model.

[0026] Explanation of the reference numerals: 1. Shell; 2. Feeding pipe; 3. Cover plate; 4. Receiving hopper; 5. Reduction motor; 6. Scraping assembly; 61. Support frame; 62. Scraper; 63. Fixed frame; 64. Slide plate; 65. Slide groove; 67. Shrapnel; 7. Filter hopper; 8. Steam generator; 9. Connecting frame; 10. Rotating shaft. DETAILED DESCRIPTION

[0027] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0028] It should be noted that the structures, proportions, sizes, etc. illustrated in the drawings of this specification are only used to match the contents disclosed in the specification for people familiar with this technology to understand and read, and are not used to limit the conditions under which this application can be implemented. Therefore, they have no substantive technical significance. Any structural modification, change in proportional relationship or adjustment of size should still fall within the scope of the technical content disclosed in this application without affecting the effects and purposes that can be achieved by this application.

[0029] Example

[0030] In the prior art, after the liquid raw materials of biopharmaceuticals are sterilized and filtered inside the filter bucket, due to the viscosity and surface tension of the physical properties of the liquid raw materials of biopharmaceuticals, some of the liquid raw materials of biopharmaceuticals will remain on the inner wall surface of the filter bucket, resulting in the problem of reduced purity of the subsequent production environment of the liquid raw materials of biopharmaceuticals.

[0031] See also Figure 1-6 The utility model provides a technical solution: a biopharmaceutical sterilization and filtration device, comprising a housing 1, the top of the housing 1 is connected with a feeding pipe 2 for filling biopharmaceutical raw materials, the top of the feeding pipe 2 is threadedly connected with a cover plate 3, the liquid raw materials of biopharmaceuticals are filled into the interior of the filter bucket 7 through the feeding pipe 2, and then the cover plate 3 is screwed on the top end of the feeding pipe 2;

[0032] A connecting frame 9 is fixed inside the shell 1, and a filter bucket 7 for filtering biopharmaceutical raw materials is fixed at the bottom of the connecting frame 9. A steam generator 8 for high-temperature sterilization of biopharmaceutical raw materials is installed on the top of the inner wall of the shell 1. The steam generator 8 generates high-temperature steam to sterilize the liquid raw materials of biopharmaceuticals at high temperature. A reduction motor 5 is fixed at the top center of the shell 1, and a rotating shaft 10 is fixed to the output shaft end of the reduction motor 5. The outer side of the rotating shaft 10 is rotatably connected to the top center of the shell 1 through a sealed bearing. The shape of the rotating shaft 10 is cylindrical, and a scraping component 6 for scraping residual liquid on the inner wall of the filter bucket 7 is provided on one side of the rotating shaft 10. A receiving hopper 4 is inserted into one side of the bottom of the shell 1, and the receiving hopper 4 is located on the lower side of the filter bucket 7.

[0033] The scraping assembly 6 includes a support frame 61, and two fixing frames 63 are fixed on one side of the support frame 61. A slide groove 65 is opened inside the fixing frame 63, and a slide plate 64 is slidably connected to the inner side of the slide groove 65. A scraper 62 that seamlessly penetrates one side of the fixing frame 63 is fixed on one side of the slide plate 64. Under the elastic force of the spring piece 67, the slide plate 64 is pushed to fit the inner side wall of the slide groove 65, so that the scraper 62 fits the inner wall side of the filter bucket 7, and the outer side of the scraper 62 is slidably connected to the inner side wall of the filter bucket 7. A spring piece 67 is connected between one side of the slide plate 64 and the inner side wall of the slide groove 65. One side of the two support frames 61 is fixed to the outer side of the rotating shaft 10, and the biomedical liquid raw materials remaining on the side wall and bottom of the filter bucket 7 are scraped off to prevent the biomedical liquid raw materials from remaining on the inner wall side of the filter bucket 7 after filtration. By scraping off the residue on the inner wall side of the filter bucket 7, it can effectively prevent the biomedical liquid raw materials from remaining on the inner wall side of the filter bucket 7 after filtration, which helps to reduce the residue of pollutants.

[0034] Working principle or structural principle: When it is necessary to sterilize and filter the liquid raw materials of biopharmaceuticals, first, add the liquid raw materials of biopharmaceuticals into the filter bucket 7 through the feeding tube 2, then tighten the cover plate 3 at the top end of the feeding tube 2, and then press the switch to start the steam generator 8. At this time, the steam generator 8 generates high-temperature steam to sterilize the liquid raw materials of biopharmaceuticals at high temperature. At the same time, the filter bucket 7 filters the biopharmaceutical liquid raw materials inside it, and the filtered biopharmaceutical liquid raw materials drip into the receiving hopper 4. When the receiving hopper 4 is full of the filtered biopharmaceutical liquid raw materials, the receiving hopper 4 can be taken out. Using high-temperature steam to sterilize the liquid raw materials of biopharmaceuticals can effectively kill various microorganisms, ensure the sterility of the product, and meet the high standards of biopharmaceuticals. The filter bucket 7 can effectively remove solid impurities and particles in the liquid raw materials to ensure the purity of the final product.

[0035] When the filter hopper 7 is filtering the biopharmaceutical liquid raw material, the reduction motor 5 drives the rotating shaft 10 and the support frame 61 to rotate. When the support frame 61 rotates in the biopharmaceutical liquid raw material, the biopharmaceutical liquid raw material can be stirred. After the filtration of the biopharmaceutical liquid raw material is completed, the switch is pressed to start the reduction motor 5. At this time, the reduction motor 5 drives the rotating shaft 10 and the two fixing frames 63 to rotate. At this time, under the elastic force of the spring piece 67, the slide plate 64 is pushed to fit the inner wall of the slide groove 65, so that the scraper 62 fits the inner wall side of the filter hopper 7, and the biopharmaceutical liquid raw material remaining on the side wall and bottom of the filter hopper 7 is scraped off to avoid the biopharmaceutical liquid raw material remaining on the inner wall side of the filter hopper 7 after filtration. By scraping off the residue on the inner wall side of the filter hopper 7, it can effectively avoid the biopharmaceutical liquid raw material remaining on the inner wall side of the filter hopper 7 after filtration, which helps to reduce the residue of pollutants and ensure the purity and safety of subsequent production links.

[0036] By replacing the stirring rod with the support frame 61, stirring the biopharmaceutical liquid raw material can prevent it from settling or forming an uneven suspension, thereby ensuring that the liquid can pass through the filter bucket 7 evenly and quickly during the filtration process, thereby improving the filtration efficiency. At the same time, stirring helps prevent particles from accumulating on the filter bucket 7, reducing the risk of blockage and keeping the filter bucket 7 unobstructed.

[0037] Those skilled in the art will appreciate that the features described in the various embodiments and / or claims of the present invention may be combined and / or combined in various ways, even if such combinations and / or combinations are not explicitly described in the present invention. In particular, the features described in the various embodiments and / or claims of the present invention may be combined and / or combined in various ways without departing from the spirit and teachings of the present invention. All of these combinations and / or combinations fall within the scope of the present invention.

Claims

1. A biopharmaceutical sterilization filtration device, comprising a housing (1), characterized in that: The top of the shell (1) is connected to a feeding pipe (2) for filling biopharmaceutical raw materials, and the top of the feeding pipe (2) is threadedly connected to a cover plate (3); A connecting frame (9) is fixed inside the shell (1), a filter bucket (7) for filtering biopharmaceutical raw materials is fixed at the bottom of the connecting frame (9), and a steam generator (8) for high-temperature sterilization of biopharmaceutical raw materials is installed at the top of the inner wall of the shell (1); A reduction motor (5) is fixed at the top center of the housing (1), a rotating shaft (10) is fixed to the output shaft end of the reduction motor (5), and a scraping component (6) for scraping residual liquid on the inner wall of the filter bucket (7) is arranged on one side of the rotating shaft (10).

2. A biopharmaceutical sterilization filtration device according to claim 1, characterized in that: A material receiving hopper (4) is inserted into one side of the bottom of the shell (1), and the material receiving hopper (4) is located at the lower side of the filter hopper (7).

3. A biopharmaceutical sterilization filtration device according to claim 1, characterized in that: The scraping assembly (6) comprises a support frame (61), two fixing frames (63) are fixed on one side of the support frame (61), and a slide groove (65) is provided inside the fixing frame (63).

4. A biopharmaceutical sterilization filtration device according to claim 3, characterized in that: A slide plate (64) is slidably connected to the inner side of the slide groove (65), and a scraper plate (62) is fixed to one side of the slide plate (64) and seamlessly penetrates one side of the fixing frame (63).

5. A biopharmaceutical sterilization filtration device according to claim 4, characterized in that: The outer side of the scraper (62) is slidably connected to the inner side wall of the filter bucket (7), and a spring piece (67) is connected between one side of the slide plate (64) and the inner side wall of the slide groove (65).

6. A biopharmaceutical sterilization filtration device according to claim 5, characterized in that: One side of the two support frames (61) is fixed to the outer side of the rotating shaft (10).

7. The biopharmaceutical sterilization filtration device according to claim 1, characterized in that: The outer side of the rotating shaft (10) is rotatably connected to the top center of the housing (1) via a sealed bearing, and the rotating shaft (10) is in the shape of a cylinder.

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