Multifunctional antibody diluter

By designing a multifunctional antibody diluent, using a quantitative infusion device, an electric heating plate, agitating rod and a nozzle, the pollution problem caused by wear of the stirring structure in the existing antibody diluent is solved, and convenient cleaning and temperature adjustment effects are achieved.

CN222641767UActive Publication Date: 2025-03-21ANHUI PUER BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202421310562.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-11
Publication Date
2025-03-21
Estimated Expiration
2034-06-11

AI Technical Summary

Technical Problem

Existing antibody dilutors have problems such as abrasive structure wear and contamination, and inconvenience in cleaning the container.

Method used

A multifunctional antibody diluent is designed, which adopts a structure such as quantitative infusion device, electric heating plate, stirring rod, stirring blade, side scraper, bottom scraper and spray head. The stirring rod and stirring blade are driven by the motor, and a comprehensive cleaning effect is achieved through the water pump and spray head.

Benefits of technology

It effectively avoids the occurrence of contamination during the stirring process, and facilitates cleaning of the diluent, improving the temperature adjustment and cleaning effect during the dilution process.

✦ Generated by Eureka AI based on patent content.

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    Figure CN222641767U_ABST
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Abstract

The utility model provides a multifunctional antibody diluter, which relates to the field of antibody diluters and comprises a diluter main body, a quantitative filling device is mounted on the outer wall of the diluter main body, a motor is arranged at the top of the diluter main body, a lifting plate is mounted on the lower side of the motor, a stirring rod is connected to the output shaft end of the motor, and the stirring rod is connected with the lifting plate. Side scraping plates are connected to the outer sides of the stirring rods through telescopic assemblies, bottom scraping plates are connected to the lower ends of the stirring rods, stirring blades are connected to the outer sides of the stirring rods, water tanks are arranged at the positions, on the two sides of the lifting plate, of the top of the diluter body, and water pipes are connected to the outer sides of the water tanks through water pumps; the water pipe is inserted into the diluter body and connected with the annular pipe, and meanwhile the lower side of the annular pipe is connected with the spray heads arranged at equal intervals in the circumferential direction. The antibody diluter disclosed by the utility model solves the problems of pollution caused by abrasion of a stirring structure and inconvenience for cleaning a container in the existing antibody diluter.
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Description

Technical Field

[0001] The utility model relates to the technical field of antibody diluters, in particular to a multifunctional antibody diluter. Background Art

[0002] Antibodies are protective proteins produced by the body in response to antigen stimulation. They are large Y-shaped proteins secreted by plasma cells and used by the immune system to identify and neutralize foreign substances such as bacteria and viruses. During the antigen-antibody reaction, antibodies need to be diluted to match the antigen, so a reagent antibody diluter is needed. After searching, the prior art (Announcement No.: CN219502658U) records that "a reagent antibody diluter belongs to the technical field of medical instruments to solve the problem of difficulty in controlling the amount of antibodies and diluents entering the diluter, including a diluter body and a pull rod, and an electric guide rail slider is fixedly connected to the bottom of the pull rod. The present application sets a pull rod, and when the user needs to dilute the antibody, the user can pull out the pull rod, remove the left tube body and the right tube body on the pull rod, and add a certain amount of antibody and diluent to the left tube body and the right tube body, and then the user can reinsert the pull rod into the diluter body, and then the user can control the electric guide rail slider to move to the left and right sides, so that the fixed plate drives the left tube body and the right tube body to separate, so that the certain amount of antibody and diluent in the left tube body and the right tube body enter the diluter body, which is convenient for the user to control the amount entering the diluter body, so that the antibody dilution can be carried out accurately."

[0003] Although the reagent antibody diluter in the prior art achieves a uniform stirring and mixing effect, it still has some shortcomings: the relative movement between the gears, racks, reciprocating screws and transmission plates involved in the existing antibody diluter causes friction, which inevitably produces friction impurities in the material, thereby contaminating the antibodies and diluents; secondly, it is not convenient to clean the inner wall of the container after use, resulting in functional deviations in use. Utility Model Content

[0004] In order to overcome the defects of the prior art, a multifunctional antibody diluter is provided to solve the problems of the existing antibody diluter, such as the abrasion of the stirring structure leading to contamination and the inconvenience in cleaning the container.

[0005] To achieve the above-mentioned purpose, a multifunctional antibody diluter is provided, comprising: a diluter body, a quantitative filler is installed on the outer wall of the diluter body, a motor is provided on the top of the diluter body, and a lifting plate is installed on the lower side of the motor, and a stirring rod is connected to the output shaft end of the motor, the outer side of the stirring rod is connected to a side scraper through a telescopic component, and the lower end of the stirring rod is connected to a bottom scraper, and the outer side of the stirring rod is connected to a stirring blade, a water tank is provided on the top of the diluter body and on both sides of the lifting plate, and the outer side of the water tank is connected to a water pipe through a water pump, and the water pipe is inserted into the diluter body and connected to an annular pipe, and the lower side of the annular pipe is connected to equidistantly arranged nozzles in the circumferential direction.

[0006] Furthermore, a discharge port is provided on an outer wall of one side of the diluter body close to the bottom, and the discharge port is configured as a horizontal pipe structure, and an electrically controlled valve is installed in the horizontal pipe.

[0007] Furthermore, an electric push rod is connected to the lower end of the lifting plate, and a guide rod vertically penetrates the edge of the lifting plate, and both the guide rod and the electric push rod are fixed to the top of the diluter body.

[0008] Furthermore, the annular tube is fixed to the inner wall of the diluter body, and the annular tube is located on the upper side of the stirring rod, and the nozzle is tilted toward the inner wall of the diluter body and the stirring rod.

[0009] Furthermore, the telescopic assembly includes a sleeve horizontally connected to the stirring rod, and a slider and a spring are slidably connected inside the sleeve, and the outer end of the slider is connected to the sliding rod.

[0010] Furthermore, a sealing ring is provided at the connection between the slide rod and the outer end of the sleeve, and a spring is sleeved on the outer side of the slide rod, and the outer end of the slide rod is connected to the side scraper. At the same time, the outer side of the side scraper and the lower side of the bottom scraper are provided with elastic edges made of rubber material.

[0011] Furthermore, a heat-conducting wall is provided on the inner wall of the diluter body, and an electric heating plate is provided on the inner side of the heat-conducting wall, and the electric heating plate is electrically connected to an external temperature controller.

[0012] The beneficial effects of the utility model are:

[0013] 1. When in use, the quantitative dosing device is used to quantitatively add the diluent and antibody solution into the main container of the diluter, and then the electric heating plate is heated by the external temperature controller, and then the internal mixed liquid is heated by the heat-conducting wall, so as to increase the appropriate moisture absorption temperature and accelerate the dilution effect. At the same time, the motor, stirring rod and stirring blade are used to stir the internal mixed liquid, and the movement friction between the components is avoided during the stirring process, thereby avoiding the generation of impurities and ensuring that the internal solution is not contaminated;

[0014] 2. When cleaning, start the water pump to pump the clean water in the water tank into the annular tube through the water pipe, then use the nozzle to spray water to rinse the inner wall of the diluter body and the middle stirring rod component, then start the motor and increase the speed of the motor, so that the sliding rod included in the telescopic assembly is thrown outward under the action of centrifugal force, thereby pushing the elastic edge of the side scraper to slide in contact with the inner wall of the diluter body, and at the same time, the motor is moved downward by the electric push rod and the lifting plate, and then the bottom scraper is driven downward by the stirring rod, so that the elastic edge of the bottom scraper slides in contact with the bottom inner wall of the diluter body, thereby achieving a more comprehensive cleaning effect and improving the functionality of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a front view cross-sectional structural schematic diagram of an embodiment of the utility model.

[0016] Figure 2 For the utility model embodiment Figure 1 Schematic diagram of the structure at point A in the middle.

[0017] Figure 3 For the utility model embodiment Figure 1 Schematic diagram of the structure at point B in the middle.

[0018] Figure 4 This is a bottom view of the annular tube structure of an embodiment of the utility model.

[0019] In the figure: 1. diluter body; 11. quantitative filler; 12. discharge port; 13. electric heating plate; 14. heat-conducting wall; 2. motor; 21. lifting plate; 22. electric push rod; 23. guide rod; 24. stirring rod; 25. stirring blade; 26. side scraper; 261. elastic edge; 27. bottom scraper; 3. water tank; 31. water pipe; 32. annular pipe; 321. nozzle; 4. telescopic component; 41. sleeve; 42. slider; 43. slide rod; 44. spring; 45. sealing ring. DETAILED DESCRIPTION

[0020] Reference Figures 1 to 4As shown, the utility model provides a multifunctional antibody diluter, comprising: a diluter body 1, a quantitative filler 11 is installed on the outer wall of the diluter body 1, a motor 2 is provided on the top of the diluter body 1, and a lifting plate 21 is installed on the lower side of the motor 2, and a stirring rod 24 is connected to the output shaft end of the motor 2, and a side scraper 26 is connected to the outer side of the stirring rod 24 through a telescopic component 4, and a bottom scraper 27 is connected to the lower end of the stirring rod 24, and a stirring blade 25 is connected to the outer side of the stirring rod 24, a water tank 3 is provided on the top of the diluter body 1 and on both sides of the lifting plate 21, and a water pipe 31 is connected to the outer side of the water tank 3 through a water pump, and the water pipe 31 is inserted into the inside of the diluter body 1 and connected to the annular pipe 32, and the lower side of the annular pipe 32 is connected to equidistantly arranged nozzles 321 in the circumferential direction.

[0021] In this embodiment, the diluter body 1 includes an internal structure, and the motor 2 and the water tank 3 on the outside constitute the main structure of the multifunctional antibody diluter involved in this application.

[0022] Specifically, the quantitative filler 11 adopts the liquid quantitative filler 11 equipment under the existing technology.

[0023] Specifically, the stirring rods 24 are provided with two vertically parallel stirring blades 25 , and the stirring blades 25 are interlaced with each other, and through holes are provided on the surfaces of the stirring blades 25 , thereby increasing the turbulent flow effect during stirring.

[0024] Specifically, the water tank 3 and the correspondingly connected water pump are both provided with two groups, so that the water flushing pressure of the annular pipe 32 and the nozzle 321 is maintained during use.

[0025] like Figure 1 As shown, a discharge port 12 is provided on the outer wall of one side of the diluter body 1 near the bottom, and the discharge port 12 is set as a horizontal pipe structure, and an electric control valve is installed in the horizontal pipe. A heat-conducting wall 14 is provided on the inner wall of the diluter body 1, and an electric heating plate 13 is provided on the inner side of the heat-conducting wall 14, and the electric heating plate 13 is electrically connected to an external temperature controller.

[0026] As a preferred embodiment, by providing the electric heating plate 13 and the heat-conducting wall 14, it is convenient to adjust the temperature inside the diluter body 1, and further to adjust the required temperature according to different antibodies and diluent mixtures.

[0027] Specifically, a temperature sensor is provided inside the diluter body 1 and is connected to an external temperature controller.

[0028] like Figure 1 and Figure 4As shown, the lower end of the lifting plate 21 is connected to an electric push rod 22, and a guide rod 23 vertically penetrates the edge of the lifting plate 21, and the guide rod 23 and the electric push rod 22 are both fixed to the top of the diluter body 1, and the annular tube 32 is fixed to the inner wall of the diluter body 1, and the annular tube 32 is located on the upper side of the stirring rod 24, and the nozzle 321 is inclined toward the inner wall of the diluter body 1 and the stirring rod 24.

[0029] Specifically, the direction of the nozzle 321 is partially inward and partially outward, so as to achieve a wide range of flushing. At the same time, due to the high-speed rotation of the stirring rod 24 during flushing, the flushing effect facilitates the removal of residues through centrifugal force.

[0030] like Figure 1 and Figure 4 As shown, the telescopic assembly 4 includes a sleeve 41 horizontally connected to the stirring rod 24, and the inside of the sleeve 41 is slidably connected with a slider 42 and a spring 44, and the outer end of the slider 42 is connected to a slide rod 43, and a sealing ring 45 is provided at the connection between the slide rod 43 and the outer end of the sleeve 41, and the spring 44 is sleeved on the outside of the slide rod 43, and the outer end of the slide rod 43 is connected to the side scraper 26, and at the same time, the outer side of the side scraper 26 and the lower side of the bottom scraper 27 are provided with elastic edges 261 made of rubber material.

[0031] Specifically, when the stirring rod 24 is stirring normally, the speed of the telescopic assembly 4 will not cause the telescopic assembly 4 to unfold, that is, the centrifugal force of rotation is smaller than the elastic force of the spring 44, and the spring 44 will not be compressed.

[0032] It should be noted that all the components in the diluter body 1 that are in contact with the antibody and the diluent are made of materials that do not chemically react with the mixed solution.

[0033] When in use, a quantitative filler is used to conveniently add the diluent and antibody solution into the diluter main body container in a quantitative manner, and then the electric heating plate is heated by an external temperature controller, and then the internal mixed liquid is heated by the heat-conducting wall, so as to increase the appropriate moisture absorption temperature and accelerate the dilution effect. At the same time, the internal mixed liquid is stirred by the motor, the stirring rod and the stirring blade. When cleaning, the water pump is started to pump the clean water in the water tank into the annular tube through the water pipe, and then the inner wall of the diluter main body and the middle stirring rod component are sprayed with water through the nozzle, and then the motor is started and the speed of the motor is increased, so that the sliding rod included in the telescopic assembly is thrown outward under the action of centrifugal force, thereby pushing the elastic edge of the side scraper to slide in contact with the inner wall of the diluter main body, and at the same time, the motor is moved downward by the electric push rod and the lifting plate, and then the bottom scraper is driven to move downward by the stirring rod, so that the elastic edge of the lower side of the bottom scraper is in sliding contact with the bottom inner wall of the diluter main body, thereby achieving a more comprehensive cleaning effect.

[0034] The multifunctional antibody diluter of the utility model can effectively solve the problems of existing antibody diluters that the stirring structure is worn out and causes pollution, and that it is inconvenient to clean the container. It achieves the purpose of avoiding pollution during the antibody dilution and stirring process on the basis of the existing multifunctional antibody diluter technology, and is convenient for cleaning the diluter and temperature regulation during the dilution process.

Claims

1. A multifunctional antibody diluter, comprising: A diluter body (1) is characterized in that: a quantitative injector (11) is installed on the outer wall of the diluter body (1), a motor (2) is provided on the top of the diluter body (1), and a lifting plate (21) is installed on the lower side of the motor (2), and a stirring rod (24) is connected to the output shaft end of the motor (2), the outer side of the stirring rod (24) is connected to a side scraper (26) through a telescopic component (4), and the lower end of the stirring rod (24) is connected to a bottom scraper (27), and the outer side of the stirring rod (24) is connected to a stirring blade (25), a water tank (3) is provided on the top of the diluter body (1) and on both sides of the lifting plate (21), and the outer side of the water tank (3) is connected to a water pipe (31) through a water pump, and the water pipe (31) is inserted into the inside of the diluter body (1) and connected to an annular pipe (32), and the lower side of the annular pipe (32) is connected to nozzles (321) arranged equidistantly in the circumferential direction.

2. A multifunctional antibody diluter according to claim 1, characterized in that: A discharge port (12) is provided on an outer wall of one side of the diluter body (1) close to the bottom, and the discharge port (12) is configured as a horizontal pipe structure, and an electric control valve is installed in the horizontal pipe.

3. A multifunctional antibody diluter according to claim 1, characterized in that: The lower end of the lifting plate (21) is connected to an electric push rod (22), and a guide rod (23) vertically penetrates the edge of the lifting plate (21), and the guide rod (23) and the electric push rod (22) are both fixed to the top of the diluter body (1).

4. A multifunctional antibody diluter according to claim 1, characterized in that: The annular tube (32) is fixed to the inner wall of the diluter body (1), and the annular tube (32) is located on the upper side of the stirring rod (24), while the nozzle (321) is inclined towards the inner wall of the diluter body (1) and the stirring rod (24).

5. A multifunctional antibody diluter according to claim 1, characterized in that: The telescopic assembly (4) comprises a sleeve (41) horizontally connected to the stirring rod (24), a slider (42) and a spring (44) are slidably connected inside the sleeve (41), and a slide bar (43) is connected to the outer end of the slider (42).

6. A multifunctional antibody diluter according to claim 5, characterized in that: A sealing ring (45) is provided at the connection between the slide bar (43) and the outer end of the sleeve (41), and the spring (44) is sleeved on the outer side of the slide bar (43). The outer end of the slide bar (43) is connected to the side scraper (26), and the outer side of the side scraper (26) and the lower side of the bottom scraper (27) are both provided with elastic edges (261) made of rubber material.

7. A multifunctional antibody diluter according to claim 1, characterized in that: The inner wall of the diluter body (1) is provided with a heat-conducting wall (14), and the inner side of the heat-conducting wall (14) is provided with an electric heating plate (13), and the electric heating plate (13) is electrically connected to an external temperature controller.

Citation Information

Patent Citations

  • Reagent antibody diluter

    CN219502658U