Method for preparing Xanthoceras sorbifolia husk total saponin extractive

Abstract

The present invention provides a preparation method for fruit pericaryon total saponin extract. The present method takes advantage of water extract and alcohol precipitation to prepare fruit pericaryon total saponin. The macroporous resin is purified and magnesium-bleached and dried. The prepared total saponin is more than 40 percent of the fruit pericaryon total saponin extract in weight. The fruit pericaryon total saponin prepared through the method can be used independently or be combined with other drugs as pharmaceutical raw materials used in the treatment of various related diseases. The advanced nature and practical value of the method is that the purity of the prepared fruit pericaryon total saponin in high. The method is simple, prectival, cheap and safe. The method is suitable for industrial production.

Description

technical field

[0001] The invention relates to a method for extracting and preparing medicinal raw materials, in particular to a new method for preparing total saponin extract from sorbifolia husk. The method of the present invention refers to the process of extracting and preparing the total saponins extract of X. sorbifolia husk (comprising the peduncle) through water extraction, alcohol precipitation, separation and purification through macroporous adsorption resin and magnesium oxide decolorization. method. Background technique

[0002] Xanthoceras sorbifolia Bunge is a plant of the genus Xanthoceras in the family Sapindaceae. Shrubs or trees, distributed in Liaoning, Hebei, Shaanxi and other provinces of China, wild or cultivated, are unique woody oil crops in my country. The heartwood, stems and fruits of X. sorbifolium can be used as medicine. The stems and branches are mainly used to treat rheumatoid arthritis, skin wind-heat and other diseases. Seed kernels are m...

Examples

Embodiment 1

[0017] 1 kg of Xantho sorbifolium husk (including the peduncle) coarse powder, soak and extract three times with 12 times, 10 times and 8 times the amount of water at 80°C, 2 hours each time, filter, combine the filtrates, stand still for 12 hours, filter Get the supernatant, concentrate to 5 liters, add 95% ethanol to 70% alcohol content, stand still for 12 hours, filter the supernatant, concentrate under reduced pressure until there is no alcohol smell, put on the macroporous adsorption resin AB-8 column ( Nankai University Resin Factory, 2 liters), washed with water until the color is very light, and then washed with 70% ethanol, the resulting ethanol eluate was decolorized by adding 80 grams per liter of magnesium oxide for reflux for 1 hour, filtered, and the filtrate was concentrated under reduced pressure and sprayed 80 grams (yield: 8%) of dry Xanthos sorbifolium husk extract, the total saponin content is 73%.

technical field

[0001] The invention relates to a method for extracting and preparing medicinal raw materials, in particular to a new method for preparing total saponin extract from sorbifolia husk. The method of the present invention refers to the process of extracting and preparing the total saponins extract of X. sorbifolia husk (comprising the peduncle) through water extraction, alcohol precipitation, separation and purification through macroporous adsorption resin and magnesium oxide decolorization. method. Background technique

[0002] Xanthoceras sorbifolia Bunge is a plant of the genus Xanthoceras in the family Sapindaceae. Shrubs or trees, distributed in Liaoning, Hebei, Shaanxi and other provinces of China, wild or cultivated, are unique woody oil crops in my country. The heartwood, stems and fruits of X. sorbifolium can be used as medicine. The stems and branches are mainly used to treat rheumatoid arthritis, skin wind-heat and other diseases. Seed kernels are m...

Examples

Embodiment 1

[0017] 1 kg of Xantho sorbifolium husk (including the peduncle) coarse powder, soak and extract three times with 12 times, 10 times and 8 times the amount of water at 80°C, 2 hours each time, filter, combine the filtrates, stand still for 12 hours, filter Get the supernatant, concentrate to 5 liters, add 95% ethanol to 70% alcohol content, stand still for 12 hours, filter the supernatant, concentrate under reduced pressure until there is no alcohol smell, put on the macroporous adsorption resin AB-8 column ( Nankai University Resin Factory, 2 liters), washed with water until the color is very light, and then washed with 70% ethanol, the resulting ethanol eluate was decolorized by adding 80 grams per liter of magnesium oxide for reflux for 1 hour, filtered, and the filtrate was concentrated under reduced pressure and sprayed 80 grams (yield: 8%) of dry Xanthos sorbifolium husk extract, the total saponin content is 73%.