Traditional Chinese medicine composition for treating liver cirrhosis and fibrosis and preparation method thereof

A composition and fibrosis technology, which can be applied in the direction of drug combinations, pharmaceutical formulas, and medical preparations containing active ingredients, etc., can solve the problems of difficult to determine curative effect, no ideal toxicity of liver fibrosis, and high incidence of liver cirrhosis

CN102772737BInactive Publication Date: 2014-02-26HUANGHUAI UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Publication Date
2014-02-26
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a traditional Chinese medicine composition for treating liver cirrhosis and fibrosis and a preparation method thereof. The traditional Chinese medicine composition is mainly prepared by the bulk drugs of radix salviae miltiorrhizae, black soya bean, red paeony root, ophiopogon root, astragalus root, radix codonopsis pilosulae, angelica, carapax amydae, rhizoma zedoariae, twotooth achyranthes root, Chinese yam, giant knotweed, hedyotis diffusa, fructus amomi and honey-fried licorice root. The prescription disclosed by the invention is complete in the matching of a monarch, a minister, an adjuvant and a conductant drug, is excellent in the efficacy of drugs, is flexible in application and has the comparatively obvious characteristic of traditional Chinese medicine. The traditional Chinese medicine composition disclosed by the invention has the actions of resisting the fibrosis, resisting hepatitis B virus (HBV) replication, improving the liver function, regulating the blood circulation of the liver, reinforcing the liver, softening hard masses, strengthening the spleen and the like; and the traditional Chinese medicine composition also has the actions of lowering the portal pressure, reducing the thickness of the spleen and improving the liver function. The traditional Chinese medicine composition disclosed by the invention has an obvious curative effect in the therapeutic action to the liver cirrhosis and fibrosis. In addition, the traditional Chinese medicine composition disclosed by the invention has an obvious action of resisting the liver cirrhosis and fibrosis of children.
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Description

technical field

[0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating liver cirrhosis and fibrosis and a preparation method thereof. Background technique

[0002] Liver fibrosis and cirrhosis are chronic progressive liver diseases characterized by excessive collagen fiber deposition in the liver caused by liver inflammation or direct toxic injury. Liver fibrosis can lead to hepatic sinusoidal capillarization, increased sinusoidal pressure, and intrahepatic microcirculation disturbance, affecting the material exchange between blood and liver cells, which in turn aggravates liver cell damage, further develops liver fibrosis and forms a vicious circle. Liver cirrhosis is based on diffuse liver fibrosis. Due to the compensatory nodular regeneration of liver cells and the regeneration of connective tissue, changes in liver tissue structure and reduction of functional liver cells lead to...

Examples

Embodiment 1

[0150] The dosage form of the above-mentioned traditional Chinese medicine composition for treating liver cirrhosis and fibrosis of the present invention can be decoction, powder or pill, and the preparation method of the decoction, powder and pill thereof is detailed in the third part of the content of the invention, and will not be described in detail here .

[0151] Embodiment 2: basically the same as Embodiment 1, the difference is:

Embodiment 2

[0152] The present invention is used to treat the Chinese medicine composition of liver cirrhosis and fibrosis, expressed in parts by weight. The crude drug of said Chinese medicine composition consists of 15 parts of Salvia miltiorrhiza, 9 parts of black bean, 10 parts of red peony root, 12 parts of Radix Ophiopogon japonicus, 20 parts of Radix Astragali , Codonopsis 15 parts, Angelica 15 parts, Turtle Shell 10 parts, Curcuma 9 parts, Achyranthes bidentata 10 parts, Chinese yam 10 parts, Polygonum cuspidatum 10 parts, Snake Grass 10 parts, Amomum 10 parts and Zhi Licorice 7 parts.

[0153] Embodiment 3: basically the same as Embodiment 1, the difference is:

Embodiment 3

[0154] The present invention is used to treat the Chinese medicine composition of liver cirrhosis and fibrosis, expressed in parts by weight. The raw material of the Chinese medicine composition consists of 9 parts of Salvia miltiorrhiza, 7 parts of black bean, 6 parts of Radix Paeoniae Rubra, 8 parts of Ophiopogon japonicus, and 15 parts of Radix Astragali , 12 parts of Codonopsis, 8 parts of Angelica, 13 parts of Turtle Shell, 12 parts of Curcuma, 9 parts of Achyranthes bidentata, 11 parts of Chinese Yam, 8 parts of Polygonum cuspidatum, 8 parts of Snake Grass, 6 parts of Amomum japonicus and 6 parts of Zhigancao.

[0155] Embodiment 4: basically the same as Embodiment 1, the difference is: