A spaced non-slip vascular stent capable of chronic drug delivery

A vascular stent and a chronic technology, applied in the field of vascular stents, can solve problems such as poor anti-slip effect, poor thrombolytic treatment effect, and easy slippage, and achieve the effects of enhancing anti-slip effect, prolonging drug action time, and improving anti-slip performance.

CN108420576BInactive Publication Date: 2019-12-06青岛市即墨区人民医院
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Publication Date
2019-12-06
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a spacing antiskid vascular scaffold capable of slowly discharging drugs. The spacing antiskid vascular scaffold comprises a plurality main scaffolds which are parallelly arranged at intervals, the main scaffolds are fixedly connected through auxiliary scaffolds, a plurality of through holes are formed in the main scaffolds, the auxiliary scaffolds are inserted into the through holes, gaps are reserved among the auxiliary scaffolds and the outer side walls of the main scaffolds, drug cavities are formed among the main scaffolds and the auxiliary scaffolds, and drug discharging holes are formed in one side, close to the outer wall of the corresponding main scaffold, of each drug cavity. According to the vascular scaffold, the main scaffolds are arranged at intervals,antiskid effect is further enhanced, the action time of thrombolysis drugs can be greatly prolonged through action of the drug cavities and the drug discharging holes, and the vascular scaffold is quite effective and worthy of popularization.
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Description

technical field

[0001] The invention relates to the technical field of vascular stents, in particular to a spaced non-slip vascular stent capable of chronic drug delivery. Background technique

[0002] Percutaneous puncture angioplasty, referred to as PTA, is under the guidance of medical imaging equipment, using a puncture needle, a guide wire and a guide sheath to insert a balloon catheter with a tightened stent into a human blood vessel and deliver it to the blood vessel At the stenosis, with the expansion of the balloon, the stent is also stretched. After the balloon is retracted and retracted, the plastically deformed metal stent remains in place and is embedded in the blood vessel, playing the role of dilating the blood vessel. This method is currently widely used in the treatment of cardiovascular diseases.

[0003] There are many forms of vascular stents in the prior art. The most common one is that the stent matrix is ​​braided with shape memory alloy wire or cut a...

Examples

Embodiment

[0040] Embodiment: Using the vascular stent of the present invention, the drug cavity of the stent is filled with 5 g of the same thrombolytic drug as in the comparative example, and then put into the blood vessel, and the remaining amount of the drug is measured and correspondingly timed.

[0041] The experimental data of the drug action time experiment are shown in Table 1 below:

[0042] Table 1

[0043]

[0044] According to the data in Table 1 above, it can be concluded that after the vascular stent in the embodiment of the present invention is placed inside the blood vessel, the drug action time is significantly improved compared with the drug action time in the comparative example.