Medical pathology slicer and method for making pathology slices using the slicer
By combining mechanical and electronic pathological slicers, using electronic control systems and vibrating cutting blades, the problems of traditional slicers being labor-intensive, noise-free and uneven cell stress are solved, and efficient and accurate pathological slices are achieved, improving pathology Quality of analysis.
Patent Information
- Application Number
- CN201811252562.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2018-10-25
- Publication Date
- 2025-01-10
- Estimated Expiration
- 2038-10-25
AI Technical Summary
Due to the mechanical movement principle, traditional pathological slicers have difficulty in slicing, high noise, high failure rate, and uneven stress on cell tissues in sections, which affects the pathological analysis results.
A pathological slicer that combines machinery and electronics is used to automate the slicing process through an electronic control system and a vibrating cutting blade to reduce the extrusion and damage of cell tissues and ensure the accuracy of slices.
It improves the slice efficiency, reduces the damage to cell tissue, ensures the microstructure integrity of the slice, and improves the accuracy of pathological analysis.
Smart Images

Figure CN109060403B_ABST
Abstract
Description
Technical Field
[0001] The invention belongs to the technical field of medical devices, and in particular relates to a medical pathology slicer and a method for making pathology slices using the slicer. Background Art
[0002] Pathological sections are physical specimens for observation under a microscope, which are taken from the diseased tissue of the diseased body and processed through a specific process during the pathological diagnosis of the patient during the operation. In modern medicine, especially in the diagnosis of tumors, pathological sections are an indispensable and important link. Pathological sectioning machine is the key equipment for making sections, and its performance and accuracy are directly related to the quality of specimen preparation of diseased tissue and the work efficiency of pathologists.
[0003] Traditional pathology slicers are mostly semi-automatic handwheel-type slicers. When slicing the object, it is mainly done through the action of "cutting". Its working principle is that the large handwheel on the right rotates to drive the specimen tissue to move up and down, and there is another small handwheel on the left to make the specimen tissue move forward and backward quickly, combined with the function of the knife holder to achieve the function of slicing. Although it has the characteristics of high work efficiency, the purely mechanical motion feeding principle makes the slicing process more laborious, mechanical collisions produce various noises, and the complex internal mechanism makes the machine have a high failure rate and difficult maintenance.
[0004] In addition, since the force direction of the blade is mainly along one side of the object being cut, it is mainly an extrusion movement at the microscopic level. Therefore, the cell tissue on the slice section will be subjected to greater and uneven force, resulting in a certain degree of tearing, thereby affecting the microscopic cell tissue structure of the slice section and having an adverse effect on pathological analysis. Summary of the invention
[0005] The present invention provides a medical pathology slicer and a method for making pathology slices using the slicer to solve the technical problems existing in the known technology.
[0006] The medical pathology slicer combines the advantages of mechanical and electronic pathology slicers, can automatically slice the object to be sliced, improves the slicing efficiency, reduces the extrusion and damage to the cell tissue structure of the sliced section caused by the pathology slicer in the prior art, and is beneficial to pathological analysis.
[0007] The technical solution adopted by the present invention to solve the technical problems existing in the known technology is:
[0008] A medical pathology slicer, characterized in that it comprises a mounting base plate and an electric control box arranged on the mounting base plate;
[0009] A cut object transmission mechanism disposed on one side of the mounting base plate and a cut object driving motor connected to the cut object transmission mechanism;
[0010] A slicing operation box fixed on the mounting base and adjacent to the slicing object transmission mechanism;
[0011] A cut object support plate bracket connected to the cut object transmission mechanism and a cut object support plate connected to the cut object support plate bracket, wherein the cut object support plate is arranged in the slicing operation box;
[0012] An upper pressing plate disposed inside the slicing operation box and capable of moving up and down along the inner wall of the slicing operation box;
[0013] An upper pressing plate transmission mechanism disposed above the slicing operation box and used to drive the upper pressing plate to move, and an upper pressing plate driving motor connected to the upper pressing plate transmission mechanism;
[0014] A cutting blade drive motor disposed on the mounting base plate and adjacent to the other side of the slicing operation box, a cutting blade transmission mechanism connected to the cutting blade drive motor, and a cutting blade vibrator;
[0015] A cutting blade disposed in a cutting blade slot of a slicing operation box and connected to a cutting blade vibrator;
[0016] a slicer tray located at the bottom of the mounting base plate and a tray drain disposed at the bottom of the slicer tray;
[0017] A PLC control system is arranged in the electric control box, and the PLC control system is electrically connected to the drive motor of the object to be cut, the drive motor of the upper pressure plate, the drive motor of the cutting blade and the vibrator of the cutting blade respectively.
[0018] The present invention can also adopt the following technical solutions:
[0019] Preferably, the slicing operation box body is an upper and lower opening structure, the upper pressure plate is arranged at the upper opening of the slicing operation box, and an upper pressure plate balance adjustment rod is installed at the four corners of the top of the upper pressure plate. The upper pressure plate balance adjustment rod is connected to the upper pressure plate balance adjustment plate, and the upper pressure plate balance adjustment plate is connected to the upper pressure plate transmission mechanism.
[0020] Preferably, the bottom of the upper pressing plate is provided with conical protrusions covering the entire surface of the plate, and a plurality of pressure sensors are also installed at the center of the bottom of the upper pressing plate.
[0021] Preferably, the upper surface of the cut object support plate located in the slicing operation box is provided with scale markings for measuring the volume of the cut object.
[0022] A method for making pathological sections using the medical pathological sectioning machine according to claim 1, characterized in that it comprises the following steps:
[0023] S1. The operator first sets the slice thickness and slice quantity according to the needs and inputs them into the electric control box;
[0024] S2, then placing the object to be cut at the center of the object support plate in the slicing operation box, and setting the running speed and stroke of the cutting blade according to the scale mark on the object support plate;
[0025] S3, starting the object drive motor of the medical pathology slicer, and pushing the object support plate upward through the object transmission mechanism;
[0026] S4, starting the upper pressing plate driving motor of the medical pathology slicer, so that the upper pressing plate transmission mechanism moves downward, and pushes the upper pressing plate downward and presses the sliced object;
[0027] S5. When the object to be cut contacts the pressure sensor at the bottom of the upper pressing plate, the object support plate stops moving upward;
[0028] S6, at this time, the cutting blade drive motor and the cutting blade transmission mechanism of the medical pathology slicer are started, and the cutting blade is driven to move forward in the horizontal direction of the object to be cut, and at the same time, the cutting blade implements the cutting operation of the object to be cut under the action of the cutting blade vibrator;
[0029] S7, when the cutting blade reaches the set stroke, the cutting blade stops cutting, that is, the cutting of a pathological section is completed;
[0030] S8, the operator starts the upper pressing plate driving motor on the slicing operation box again, so that the upper pressing plate transmission mechanism moves upward and returns to the original position, and the cutting blade automatically returns to the original position, and the pathological slices can be taken out at this time.
[0031] The advantages and positive effects of the present invention are as follows: since the present invention adopts the above technical scheme, when in use, the object to be cut is placed at the center position of the object to be cut support plate in the slicing operation box, and the running speed and stroke of the cutting blade are set according to the scale mark on the object to be cut support plate, the object to be cut driving motor is started, and the object to be cut support plate is pushed upward through the object to be cut transmission mechanism, and then the upper pressing plate driving motor is started to make the upper pressing plate transmission mechanism move downward, push the upper pressing plate downward and press the object to be cut, so that the object to be cut contacts with the pressure sensor at the bottom of the upper pressing plate, and the object to be cut support plate stops moving upward; the cutting blade driving motor and the cutting blade transmission mechanism are started, and the cutting blade is driven to move forward in the horizontal direction of the object to be cut, so that the cutting blade implements the cutting of the object to be cut under the action of the cutting blade vibrator; when the cutting blade reaches the set stroke, the cutting blade stops cutting, and the cutting of a pathological slice is completed. Since the cutting blade moves horizontally and vibrates during cutting, it can avoid the cell tissue on the slice section being subjected to large and uneven force, which may cause a certain degree of tearing, thereby ensuring the integrity of the microscopic cell tissue structure of the slice section and improving the cutting accuracy.
[0032] The medical pathology slicer combines the advantages of mechanical and electronic control systems to automatically slice the object to be sliced, improve the slicing efficiency, reduce the extrusion damage to the cell tissue structure of the sliced section caused by the pathology slicer in the prior art, and is beneficial to pathological analysis. BRIEF DESCRIPTION OF THE DRAWINGS
[0033] Figure 1 It is a schematic diagram of the structure of the present invention;
[0034] Figure 2 yes Figure 1 Right view of;
[0035] Figure 3 It is a structural schematic diagram of the upper pressing plate of the present invention;
[0036] Figure 4 yes Figure 3 AA section view;
[0037] In the figure: 1. Slicer tray; 2. Mounting base plate; 3. Cut object transmission mechanism mounting plate; 4. Cut object transmission mechanism; 5. Cut object transmission mechanism connecting plate; 6. Cut object support plate bracket; 7. Tray drain outlet; 8. Cutting blade drive motor; 9. Cut object support plate connecting plate; 10. Cut object support plate; 11. Slicing operation box; 12. Upper pressure plate; 12-1, conical protrusion; 13. Cut object drive motor; 14. Upper pressure plate balance adjustment rod; 15. Upper pressure plate balance adjustment plate; 16. Upper pressure plate transmission mechanism connecting plate; 17. Upper pressure plate drive mechanism mounting plate; 18. Upper pressure plate transmission mechanism; 19. Upper pressure plate drive motor; 20. Pressure sensor; 21. Electric control box; 22. Touch screen; 23. Cutting blade; 24. Upper pressure plate transmission mechanism support plate; 25. Cutting blade vibrator; 26. Cutting blade transmission mechanism. DETAILED DESCRIPTION
[0038] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.
[0039] See also Figure 1-Figure 4The medical pathology slicer comprises a mounting base plate 2 and an electric control box 21 arranged on the mounting base plate. A cut object transmission mechanism mounting plate 3 is fixedly mounted on one side of the mounting base plate. A cut object transmission mechanism 4 and a cut object driving motor 13 connected to the cut object transmission mechanism are mounted on the mounting base plate. A slice operation box 11 adjacent to the cut object transmission mechanism is fixed on the mounting base plate. A cut object support plate bracket 6 and a cut object support plate connecting plate 9 connected to the cut object transmission mechanism are arranged below the slice operation box. A cut object support plate 10 is connected to the cut object support plate connecting plate 9. The cut object support plate bracket 6 is connected to the cut object transmission mechanism 4 through the cut object transmission mechanism connecting plate 5. The cut object support plate 10 is arranged in the slice operation box 11. The cut object support plate bracket 6 moves up and down synchronously with the cut object transmission mechanism 4, and drives the cut object support plate 10 to move up and down in the slice operation box. An upper pressing plate 12 that can move up and down along the inner wall of the slice operation box is arranged inside the slice operation box. An upper pressure plate transmission mechanism 18 for driving the upper pressure plate to move and an upper pressure plate drive motor 19 connected to the upper pressure plate transmission mechanism are provided above the slicing operation box. The upper pressure plate transmission mechanism 18 and the upper pressure plate drive motor 19 are connected to an upper pressure plate drive mechanism mounting plate 17 arranged on the mounting base plate through an upper pressure plate transmission mechanism connecting plate 16.
[0040] A cutting blade drive motor 8 adjacent to the other side of the slicing operation box, a cutting blade transmission mechanism 26 connected to the cutting blade drive motor, and a cutting blade vibrator 25 are arranged on the installation base plate. The slicing operation box is provided with a cutting blade slot, in which a cutting blade 23 connected to the cutting blade vibrator is installed. In order to facilitate the cleaning and disinfection of the slicer, a slicer tray 1 and a tray drain port 7 arranged at the bottom of the slicer tray are arranged at the bottom of the installation base plate.
[0041] A PLC control system is arranged in the electric control box, and the PLC control system is electrically connected to the drive motor of the object to be cut, the drive motor of the upper pressure plate, the drive motor of the cutting blade and the vibrator of the cutting blade respectively.
[0042] Specifically, the slicing operation box 11 has an upper and lower opening structure, the upper pressure plate is arranged at the upper opening of the slicing operation box, and an upper pressure plate balance adjustment rod 14 is installed at the four corners of the top of the upper pressure plate. The upper pressure plate balance adjustment rod is connected to the upper pressure plate balance adjustment plate 15, and the upper pressure plate balance adjustment plate is connected to the upper pressure plate transmission mechanism 18.
[0043] Specifically, the bottom of the upper pressing plate 12 is provided with conical protrusions 12 - 1 covering the entire surface of the plate, and a plurality of pressure sensors 20 are installed at the center of the bottom of the upper pressing plate.
[0044] Specifically, the object transmission mechanism 4 includes: an upper pressure plate drive motor 19 installed on the object transmission mechanism mounting plate, a screw bracket, a screw and a linear axis, the output shaft of the upper pressure plate drive motor is connected to the screw through a motor connecting shaft, the screw bracket is fixedly connected to the object transmission mechanism mounting plate, a screw and a linear axis parallel to each other are installed on the screw bracket, a screw nut moving along the axial direction of the linear axis is provided on the screw, and screw bearings are respectively installed at both ends of the screw. A connection plate 5 of the object transmission mechanism is connected to one side of the upper pressure plate transmission mechanism, and is connected to a support plate bracket 6 of the object transmission mechanism through the connection plate 5 of the object transmission mechanism, and the support plate bracket 6 of the object transmission mechanism pushes the object support plate 10 to move up or down in the slicing operation box 11.
[0045] Specifically, the specific structure of the upper pressure plate transmission mechanism 18 is the same as that of the object transmission mechanism 4 , and the upper pressure plate transmission mechanism is connected to the upper pressure plate 12 via the upper pressure plate transmission mechanism connecting plate 16 , the upper pressure plate balance adjustment plate 15 and the upper pressure plate balance adjustment rod 14 .
[0046] Specifically, the specific structure of the cutting blade transmission mechanism 26 is the same as that of the object transmission mechanism 4. One end of the cutting blade transmission mechanism is connected to the cutting blade driving motor 8, and the other end is equipped with a cutting blade vibrator 25.
[0047] Specifically, the upper surface of the object-to-be-cut supporting plate in the slicing operation box is provided with scale markings for measuring the volume of the object to be cut.
[0048] The method for making pathological sections using the above-mentioned medical pathological section machine comprises the following steps:
[0049] S1. The operator first sets the slice thickness and the number of slices as required, and inputs them into the electric control box through the touch screen 22.
[0050] S2, then placing the object to be cut at the center of the object-carrying plate 10 in the slicing operation box 11, and setting the running speed and stroke of the cutting blade according to the scale mark on the object-carrying plate;
[0051] S3, starting the object drive motor 13 of the medical pathology slicer, and pushing the object support plate 10 upward through the object transmission mechanism 4;
[0052] S4, start the upper pressing plate driving motor 19 of the medical pathology slicer, make the upper pressing plate transmission mechanism move downward, and push the upper pressing plate downward and press the sliced object. The downward distance of the upper pressing plate is exactly the set slice thickness. For example, the slice thickness is set to 5mm. When the upper pressing plate moves downward and presses the sliced object, it can stop moving downward.
[0053] S5. When the object to be cut contacts the pressure sensor 20 at the bottom of the upper pressing plate, the object supporting plate stops moving upward.
[0054] S6. At this time, the cutting blade drive motor 8 and the cutting blade transmission mechanism 26 of the medical pathology slicer are started, and the cutting blade 23 is driven to move forward in the horizontal direction of the object to be cut. At the same time, the cutting blade vibrates left and right under the action of the cutting blade vibrator 25 to implement the cutting operation of the object to be cut.
[0055] S7. When the cutting blade reaches the set stroke, the cutting blade stops cutting, and the cutting of a pathological section is completed.
[0056] S8, the operator starts the upper pressing plate driving motor on the slicing operation box again, so that the upper pressing plate transmission mechanism moves upward and returns to the original position, and the cutting blade automatically returns to the original position, and the pathological slices can be taken out at this time.
[0057] Since the cutting blade moves horizontally and vibrates during cutting, it can avoid the cell tissue on the slice section being subjected to large and uneven force, which may cause a certain degree of tearing, thereby ensuring the integrity of the microscopic cell tissue structure of the slice section and improving the cutting accuracy.
[0058] The medical pathology slicer combines the advantages of mechanical and electronic control systems to automatically slice the object to be sliced, improve the slicing efficiency, reduce the extrusion damage to the cell tissue structure of the sliced section caused by the pathology slicer in the prior art, and is beneficial to pathological analysis.
[0059] The embodiments described in the drawings of the present invention are exemplary and are only used to explain the present invention, but should not be construed as limiting the present invention.
Claims
1. A medical pathology slicer, characterized in that: It includes a mounting base plate and an electric control box arranged on the mounting base plate; A cut object transmission mechanism disposed on one side of the mounting base plate and a cut object driving motor connected to the cut object transmission mechanism; A slicing operation box fixed on the mounting base and adjacent to the slicing object transmission mechanism; A cut object support plate bracket connected to the cut object transmission mechanism and a cut object support plate connected to the cut object support plate bracket, wherein the cut object support plate is arranged in the slicing operation box; An upper pressing plate disposed inside the slicing operation box and capable of moving up and down along the inner wall of the slicing operation box; An upper pressing plate transmission mechanism disposed above the slicing operation box and used to drive the upper pressing plate to move, and an upper pressing plate driving motor connected to the upper pressing plate transmission mechanism; A cutting blade drive motor disposed on the mounting base plate and adjacent to the other side of the slicing operation box, a cutting blade transmission mechanism connected to the cutting blade drive motor, and a cutting blade vibrator; A cutting blade disposed in a cutting blade slot of a slicing operation box and connected to a cutting blade vibrator; a slicer tray located at the bottom of the mounting base plate and a tray drain disposed at the bottom of the slicer tray; A PLC control system is arranged in the electric control box, and the PLC control system is electrically connected to the drive motor of the object to be cut, the drive motor of the upper pressure plate, the drive motor of the cutting blade and the vibrator of the cutting blade respectively.
2. The medical pathology slicer according to claim 1, characterized in that: The slicing operation box body is an upper and lower opening structure, the upper pressure plate is arranged at the upper opening of the slicing operation box, and upper pressure plate balance adjustment rods are installed at the four corners of the top of the upper pressure plate. The upper pressure plate balance adjustment rod is connected to the upper pressure plate balance adjustment plate, and the upper pressure plate balance adjustment plate is connected to the upper pressure plate transmission mechanism.
3. The medical pathology slicer according to claim 1, characterized in that: The bottom of the upper pressing plate is provided with conical protrusions covering the entire surface of the plate, and a plurality of pressure sensors are also installed at the center of the bottom of the upper pressing plate.
4. The medical pathology slicer according to claim 1, characterized in that: The upper surface of the object-to-be-cut supporting plate in the slicing operation box is provided with scale marks for measuring the volume of the object to be cut.
5. A method for making pathological sections using the medical pathological section machine according to claim 1, characterized in that: The steps include: S1. The operator first sets the slice thickness and slice quantity according to the needs and inputs them into the electric control box; S2, then placing the object to be cut at the center of the object support plate in the slicing operation box, and setting the running speed and stroke of the cutting blade according to the scale mark on the object support plate; S3, starting the object drive motor of the medical pathology slicer, and pushing the object support plate upward through the object transmission mechanism; S4, starting the upper pressing plate driving motor of the medical pathology slicer, causing the upper pressing plate transmission mechanism to move downward, and pushing the upper pressing plate downward and pressing the sliced object; S5. When the object to be cut contacts the pressure sensor at the bottom of the upper pressing plate, the object support plate stops moving upward; S6, at this time, the cutting blade drive motor and the cutting blade transmission mechanism of the medical pathology slicer are started, and the cutting blade is driven to move forward in the horizontal direction of the object to be cut, and at the same time, the cutting blade implements the cutting operation of the object to be cut under the action of the cutting blade vibrator; S7, when the cutting blade reaches the set stroke, the cutting blade stops cutting, that is, the cutting of a pathological section is completed; S8, the operator starts the upper pressing plate driving motor on the slicing operation box again, so that the upper pressing plate transmission mechanism moves upward and returns to the original position, and the cutting blade automatically returns to the original position, and the pathological slices can be taken out at this time.
Citation Information
Patent Citations
Medical pathological slicer
CN209027824U