Sample adding device, automatic sample adding machine for pipeline detection, and automatic sample adding method

Abstract

The present invention discloses a sample loading device and an assembly line type automatic sample loading machine and an automatic sample loading method, wherein the sample loading device comprises a puncture sampling needle and an injection platform, the injection platform is used to store a sample rack, and the injection platform automatically pushes the sample rack into the sample loading device through an injection pusher device; the sample loading device also comprises a sampling needle lifting assembly and a sampling needle translation assembly, the sampling needle lifting assembly is used to control the up and down movement of the puncture sampling needle, and the sampling needle translation assembly is used to control the horizontal translation movement of the puncture sampling needle. The automatic sample loading machine for assembly line detection comprises an adapter instrument placement platform for placing at least one detection instrument, a carrier device and a sample loading device, the adapter instrument placement platform and the sample loading device are respectively connected to the carrier device, and the reagent card strip is transferred to the detection instrument on the adapter instrument placement platform through the movement of the carrier device. The automatic sample loading machine is controllable in operation and has high detection efficiency.

Description

Technical Field

[0001] The invention belongs to the technical field of medical equipment, and in particular relates to a sample adding device, an automatic sample adding machine for assembly line detection, and an automatic sample adding method. Background Art

[0002] Immunofluorescence technique is the earliest developed type of labeling immunoassay technique. It is a technique established on the basis of immunology, biochemistry and microscopy. The main features of this technique are: strong specificity, high sensitivity and fast speed.

[0003] The basic principle is: a new immunoassay technique that uses fluorescein-labeled antibodies or antigens as tracers, and its principle is similar to ELISA. This method can not only quantify antigens and antibodies in liquids, but also qualitatively and quantitatively analyze antigens and antibodies in tissue sections. Generally, due to the autofluorescence of samples and reagents and the scattering of excitation light, the background fluorescence is high, which affects the sensitivity of the measurement. Lanthanide elements are generally used as fluorescent markers (tracers). After the tracer combines with the corresponding antigen or antibody, the fluorescence phenomenon is observed or the fluorescence intensity is measured with the help of a fluorescence detector, so as to determine the existence, location and distribution of the antigen or antibody or detect the content of the antigen or antibody in the specimen under test.

[0004] The current disease diagnosis process is generally to add the sample to the sample inlet of the reagent card after processing, and then manually put the reagent card into the detection analyzer for detection. It is not possible to automatically dilute and mix the sample, add the reagent card, and then automatically enter the detection analyzer for detection.

[0005] Chinese patent document (application number: 201820280185.X) discloses a sampling device and system. The sampling device includes a first drive mechanism, a second drive mechanism and a turntable. The turntable is driven to rotate by the first drive mechanism. When the reagent tube is placed in the receiving groove and the turntable rotates, and when the reagent tube is placed in the receiving groove, rotational sampling can be achieved. The sampling device is used in conjunction with a sampling needle. Compared with the linear sampling method in the prior art, this rotational sampling method is more convenient for the sampling needle to take samples, and the structure is more compact. Furthermore, the second drive mechanism drives each receiving groove to rotate, thereby driving the reagent tube placed inside the receiving groove to rotate, and then the sample in the reagent tube can be mixed. The sampling device samples the reagent tube on the turntable each time, and cannot sample continuously.

[0006] Therefore, it is necessary to develop a fully automatic sample loading device with reasonable design, controllable operation and continuous automatic sample loading, so as to improve the detection efficiency. Summary of the invention

[0007] The technical problem to be solved by the present invention is to provide a fully automatic sample adding device which has reasonable design, controllable operation, can add samples continuously and automatically, and can realize temporary adding of test samples, so as to improve the detection efficiency.

[0008] In order to solve the above technical problems, the technical solution adopted by the present invention is that the sample loading device includes a puncture sampling needle and an injection platform, the injection platform is used to store the sample rack, and the injection platform automatically pushes the sample rack into the sample loading device through an injection pusher device; the sample loading device also includes a sampling needle lifting assembly and a sampling needle translation assembly, the sampling needle lifting assembly is used to control the up and down movement of the puncture sampling needle, and the sampling needle translation assembly is used to control the horizontal translation movement of the puncture sampling needle. By adopting the above technical scheme, the puncture sampling needle is used to absorb the sample, dilute and mix the sample, and add it to the sample addition hole of the reagent card strip; the sample in the sample cup in the sample rack is absorbed by the puncture sampling needle, first diluted and mixed, and then the diluted and mixed sample is added to the reagent card strip, and then the detection work is completed by the detection instrument; continuous automatic sample addition is achieved, thereby improving the detection efficiency; the main function of the sample addition device is to automatically add the sample to the sample rack and automatically dilute and mix the sample, and add the sample to the sample injection port of the reagent card strip; such a setting can improve the detection efficiency, and a sample injection platform is set up, which can hold multiple sample racks at a time, and can be separated from the emergency mode (directly loading the sample rack from the sample rack stage).

[0009] As a preferred solution of the present invention, the sample rack is placed on a sample rack stage, and the sample rack stage is driven by a stage motion component to achieve up-down and translational motion.

[0010] A further improvement of the present invention is that the sample injection pusher device comprises a motor 1, a screw rod 1, a slider assembly, a sample injection guide rail and a sample injection pusher, one end of the screw rod 1 is connected to the motor 1, and the other end is slidably connected to the slider assembly; the slider assembly is connected to the sample injection guide rail, and the slider assembly moves linearly along the sample injection guide rail, and the slider assembly is also connected to the sample injection pusher. Thus, the sample injection pusher is driven to move, and the sample rack is pushed to move by the sample injection pusher.

[0011] A further improvement of the present invention is that the stage movement assembly includes a stage lifting assembly and a stage translation assembly, the stage lifting assembly includes a stage lifting motor, a stage lifting screw, a stage slider assembly 1 and a stage lifting guide rail, the stage lifting motor is connected to the stage slider assembly 1 through the stage lifting screw rod, one end of the stage slider assembly 1 is connected to the stage lifting guide rail, and the other end of the stage slider assembly 1 is fixedly connected to the sample rack stage; the stage lifting motor drives the stage slider assembly 1 to move up and down along the stage lifting guide rail through the stage lifting screw rod, thereby driving the sample rack stage to move up and down along the stage lifting guide rail; the stage translation assembly includes a stage translation motor The present invention relates to a machine, a translation driving wheel, a translation driven wheel, a stage slider assembly 2 and a stage translation guide rail, wherein the stage translation motor is connected to the translation driving wheel, the translation driving wheel is connected to the translation driven wheel through a translation synchronous belt, the stage translation guide rail is arranged below the translation synchronous belt, and is connected to the translation synchronous belt through the stage slider assembly 2, the stage slider assembly 2 is fixedly connected to the sample rack stage through the stage slider assembly 1, the stage translation motor drives the stage slider assembly 2 to move horizontally along the stage translation guide rail through the translation synchronous belt, thereby driving the sample rack stage to move horizontally along the stage translation guide rail; the stage lifting motor and the stage lifting guide rail are both fixed on the stage slider assembly 2. The up and down movement of the sample rack stage is realized by the cooperation of the stage lifting motor, the stage lifting screw, the stage slider assembly and the stage lifting guide rail. When the stage lifting motor is started, the stage lifting screw drives the stage slider assembly to move, the stage slider assembly is slidably connected to the stage lifting guide rail, and the stage slider assembly is fixedly connected to the sample rack stage, so the sample rack stage moves up and down along the stage lifting guide rail with the stage slider assembly; the translation movement of the sample rack stage depends on the stage translation motor, the translation driving wheel, the translation driven wheel, the stage slider assembly The stage translation motor is started, the translation driving wheel and the translation driven wheel drive the stage slider assembly 2 connected thereto to move through the translation synchronous belt, the stage slider assembly 2 is slidingly connected to the stage translation guide rail, the stage slider assembly 2 is fixedly connected to the sample rack stage through the stage slider assembly 1, so that the sample rack stage follows the stage slider assembly 2 to perform horizontal translation movement along the stage translation guide rail, and at the same time, the stage lifting motor and the stage lifting guide rail are fixedly connected to the stage slider assembly 2, thereby driving the sample rack to achieve up and down and translation movement.

[0012] A further improvement of the present invention is that the sample introduction platform is arranged on one side of the sample rack stage, the sample introduction platform is used to place a plurality of the sample racks, and the sample introduction pusher device pushes the sample racks placed in the sample introduction platform into the sample rack stage.

[0013] As a preferred solution of the present invention, the sampling needle lifting assembly includes a sampling needle lifting guide rail, a sampling needle lifting screw, a sampling needle lifting motor and a sampling needle lifting slider assembly, wherein the sampling needle lifting motor is connected to the sampling needle lifting screw, the sampling needle lifting slider assembly is slidably connected to the sampling needle lifting screw, and the sampling needle lifting slider assembly is connected to the sampling needle lifting guide rail, and the puncture sampling needle is sleeved on the sampling needle lifting slider assembly. The up and down movement of the sampling needle is achieved through the cooperation of the sampling needle lifting motor, the sampling needle lifting screw, the sampling needle lifting slider assembly and the sampling needle lifting guide rail.

[0014] As a preferred embodiment of the present invention, the sampling needle translation assembly includes a sampling needle translation motor, a sampling needle driving wheel, a sampling needle driven wheel, a sampling needle timing belt, a sampling needle horizontal slider assembly and a sampling needle horizontal guide rail. The sampling needle translation motor is connected to the sampling needle driving wheel, the sampling needle timing belt is sleeved on the sampling needle driving wheel and the sampling needle driven wheel, the sampling needle horizontal slider assembly is connected to the sampling needle timing belt, and the sampling needle horizontal slider assembly is slidably connected to the sampling needle horizontal guide rail; the sampling needle horizontal slider assembly is fixedly connected to the sampling needle lifting motor through a fixed block. The sampling needle lifting assembly is used to control the up and down movement of the puncture sampling needle, and the sampling needle translation assembly is used to control the horizontal translation movement of the puncture sampling needle, so that the puncture sampling needle can automatically move up and down to enter the sample cup or / and the diluent cup one or / and the diluent cup two to absorb and mix the sample and add the sample to the reagent card strip sample port; and the puncture sampling needle can automatically move horizontally to the sample cup or / and the diluent cup one or / and the diluent cup two and the sample port position of the reagent card strip and other positions; the lifting assembly and the translation assembly cooperate to complete the automatic sample addition process of the puncture sampling needle. Among them, the sampling needle horizontal slider assembly includes an upper fixed vertical block, the sampling needle lifting motor is fixedly connected to the fixed vertical block on the horizontal motion slider assembly through the fixed block, and the lifting guide rail is also fixedly installed on the fixed vertical block of the horizontal motion slider assembly.

[0015] A further improvement of the present invention is that the sample loading device also includes a discarding pusher and a discarding platform, the discarding platform is arranged on one side of the sample rack and the discarding pusher is arranged on the other side of the sample rack, the discarding pusher is used to push the sample rack into the discarding platform for temporary storage; the discarding pusher includes a discarding pusher motor, a pusher slider assembly, a pusher guide rail and a pusher, the discarding pusher motor is connected to the pusher slider assembly through a screw rod 2, the pusher slider is slidably connected to the pusher guide rail and moves along the pusher guide rail; the pusher slider assembly is fixedly connected to the pusher. A disposal platform and a disposal pusher are provided for automatically discarding used sample racks, which are temporarily placed on the disposal platform for subsequent waste treatment. This arrangement enables the automatic sampler to automatically and continuously load samples. The disposal pusher motor is started, and the second screw drives the pusher slider assembly to move along the pusher guide rail. The pusher slider assembly is slidably connected to the pusher guide rail, and the pusher slider assembly is fixedly connected to the pusher, so that the pusher moves along the pusher guide rail to push the sample rack into the disposal platform for temporary storage.

[0016] A further improvement of the present invention is that the sample adding device also includes a cleaning device, which is arranged below the puncture sampling needle and is used to clean the puncture sampling needle. After the sample is added, the puncture sampling needle needs to move into the cleaning device to clean the inside and outside of the puncture sampling needle so that other samples can be sucked later, thereby ensuring that the test sample is not contaminated.

[0017] A further improvement of the present invention is that the stage motion assembly further includes a stage limiting device and a sample rack hook, the stage limiting device includes a spring, an inclined surface block and a sample rack stopper, the spring is arranged below the inclined surface block, the sample rack stopper is arranged at the front end of the stage limiting device, the sample rack hook is arranged at the front end of the sample rack, when the sample rack hook reaches the middle position between the stage limiting device and the sample rack stopper, the spring of the stage limiting device ejects the inclined surface block, thereby limiting the sample rack from continuing to move forward on the sample rack stage. The front end of the sample rack is provided with a sample rack hook, the front end of the stage limiting device is provided with a sample rack stopper, when the sample rack hook reaches the middle position between the stage limiting device and the sample rack stopper, the spring of the stage limiting device ejects the inclined surface block, thereby limiting the sample rack from continuing to move forward on the sample rack stage; the sample rack hook has no limiting effect on the lateral movement of the sample rack to the disposal platform, and only has a limiting effect on the forward and backward movement of the sample rack.

[0018] As a preferred embodiment of the present invention, the sample loading device also includes a base plate, a first baffle and a second baffle, the first baffle and the second baffle are arranged in parallel and are both vertically connected to the base plate, the sample rack stage is arranged between the first baffle and the second baffle, and the sampling needle lifting assembly and the sampling needle translation assembly are arranged on the outside of the first baffle.

[0019] A further improvement of the present invention is that the sample loading device also includes a barcode scanner, which includes a sample barcode scanner and a reagent card barcode scanner. The sample barcode scanner is arranged at a position corresponding to the sample rack stage on the same side of the first baffle and the stage translation assembly, and is used to scan the barcode on the sample cup placed in the sample rack and enter information; the reagent card barcode scanner is arranged on the sampling needle horizontal slider assembly, and is used to scan the reagent card strip placed on the sample rack to confirm whether the item on the reagent card strip is the item that the sample needs to be tested. The sample rack stage moves to a suitable position, and first the sample barcode scanner scans the barcode on the sample cup and enters information, and then the reagent card barcode scanner scans the reagent card strip. After confirming that the item on the card strip is the item that the sample needs to be tested, the puncture sampling needle starts to absorb the sample and dilute and mix the sample and add the sample to the sample loading hole of the reagent card strip.

[0020] A further improvement of the present invention is that the cleaning device includes the cleaning liquid inlet system, the drainage system, the cleaning liquid side inlet, the cleaning liquid outlet and the cleaning tank, the cleaning liquid inlet system controls the entry of the cleaning liquid; the cleaning liquid side inlet is arranged on the side of the cleaning tank, the cleaning liquid outlet is arranged at the bottom of the cleaning tank, the drainage system controls the discharge of the cleaning liquid, and is connected to the cleaning liquid outlet; the cleaning device is arranged between the first baffle plate and the second baffle plate, fixedly connected to the second baffle plate, and arranged on one side of the sample rack stage. After the sample is added, the puncture sampling needle moves into the cleaning tank to clean the inside and outside of the puncture sampling needle, and the cleaning liquid enters from the cleaning liquid side inlet for cleaning, and the cleaning liquid outlet is connected to the drainage system, and the waste liquid after cleaning is discharged from the cleaning liquid outlet at the bottom through the drainage system.

[0021] As a preferred embodiment of the present invention, the discard pusher is arranged on the side of the first baffle away from the second baffle, the discard platform and the injection platform are both arranged on the side of the second baffle away from the first baffle, and the injection platform and the discard platform are both vertically connected to the second baffle, and the injection platform is arranged above the discard platform; wherein the stage guide rail is arranged between the first baffle and the second baffle, and the stage motion assembly is arranged on the outside of the first baffle.

[0022] As a preferred embodiment of the present invention, at least one sample cup and / or diluent cup and a corresponding reagent card strip are placed on the sample rack, and the reagent card strip is placed at the end of the sample rack; the puncture sampling needle draws the sample in the sample cup and adds it to the diluent cup, and then draws the sample in the diluent cup and adds it to the sample addition hole of the reagent card strip.

[0023] As a preferred embodiment of the present invention, the sample injection platform and the disposal platform are both open box-type platforms, which can accommodate up to 3 sample racks for temporary storage.

[0024] As a preferred solution of the present invention, a controller and at least one interface are provided on the side of the bottom plate for connecting the sample adding device with the outside and controlling the operation of the sample adding device.

[0025] The technical problem that the present invention needs to solve is to provide an automatic sample adding machine for pipeline detection that has a reasonable design, controllable operation and can automatically add samples continuously, thereby improving the detection efficiency.

[0026] In order to solve the above technical problems, the technical solution adopted by the present invention is that the automatic sample loading machine for assembly line detection includes an adapter instrument placement platform for placing at least one detection instrument, a carrier and a sample loading device, the adapter instrument placement platform and the sample loading device are respectively connected to the carrier, and the reagent card strip is transferred to the detection instrument on the adapter instrument placement platform by the movement of the carrier. The adapter instrument placement platform is used to place multiple detection instruments, preferably 1-3 detection instruments, and more instruments can be adapted according to detection needs. According to the detection items, the reagent card strip is automatically transported by the carrier to the corresponding detection instrument for detection, such as a fluorescent immunoassay analyzer, a biochemical analyzer, a chemiluminescence analyzer, etc.

[0027] As a preferred embodiment of the present invention, the sample loading device is provided with a sample loading and pulling device, and the transport device is provided with a card strip fixing platform and a transporting and pulling device; the card strip fixing platform and the sample rack are on the same horizontal plane, and the sample loading and pulling device moves the reagent card strip in the sample rack from the sample rack to the card strip fixing platform of the transport device, thereby transporting the reagent card strip to the detection instrument on the adapter instrument placement platform through the transport device, and then the reagent card strip is pushed into the sample inlet of the detection instrument for detection through the transporting and pulling device.

[0028] As a preferred solution of the present invention, the carrier device further comprises an up-and-down moving assembly and a horizontal translation assembly, wherein the up-and-down moving assembly comprises a lifting motor, a lifting guide rail, a lifting screw rod, a slider assembly 1 and a fixing block for the up-and-down movement of a clamping bar fixing platform, wherein the lifting motor is connected to one end of the lifting screw rod, the other end of the lifting screw rod is connected to the slider assembly 1, and the slider assembly 1 is slidably connected to the lifting guide rail; the fixing block for the up-and-down movement of the clamping bar fixing platform is connected to the slider assembly 1;

[0029] The horizontal translation assembly includes a translation guide rail, a translation motor, a translation transmission mechanism and a translation slider assembly. The translation motor is connected to the translation transmission mechanism, and the translation transmission mechanism is connected to the translation slider assembly and drives it to move horizontally on the translation guide rail. The card strip fixing platform is connected to the card strip fixing platform up and down movement fixed block; the translation slider assembly is connected to the up and down movement assembly. The reagent card strip is pushed onto the carrier device, that is, onto the card strip fixing platform by the sample adding and pushing hand device, and is pressed by the card strip fixing spring sheet. The card strip fixing platform and the sample rack are in the same horizontal plane, and the carrying and pushing hand device is behind the card strip fixing platform. At this time, the carrier device moves, and can move up and down and horizontally according to the position of the adapted detection instrument, so as to accurately reach the injection port position of the detection instrument, and then the reagent card strip is pushed into the injection port of the detection instrument by the carrying and pushing hand device.

[0030] As a preferred embodiment of the present invention, the sample adding and dialing hand device comprises a sample adding and dialing card strip dialing hand, a sample adding and dialing hand horizontal slider assembly, a sample adding and dialing hand translation guide rail, a sample adding and dialing hand lifting guide rail, a sample adding and dialing hand translation motor, a sample adding and dialing hand lifting motor, a sample adding and dialing hand lifting screw rod, a sample adding and dialing hand horizontal transmission mechanism and a sample adding and dialing hand upper and lower slider assembly, the sample adding and dialing hand translation motor is connected to the sample adding and dialing hand horizontal transmission mechanism, the sample adding and dialing hand horizontal slider assembly is fixed to the sample adding and dialing hand translation guide rail, the sample adding and dialing card strip dialing hand is connected to the sample adding and dialing hand horizontal slider assembly; at the same time, the sample adding and dialing hand horizontal slider assembly is fixedly connected to the sample adding and dialing hand lifting motor and the sample adding and dialing hand lifting guide rail; the sample adding and dialing hand lifting motor is connected to the sample adding and dialing hand lifting screw rod, the sample adding and dialing hand lifting screw rod is connected to the sample adding and dialing hand upper and lower slider assembly, the sample adding and dialing hand upper and lower slider assembly is slidably connected to the sample adding and dialing card strip dialing hand;

[0031] The carrying and pulling hand device includes a carrying card bar pull hand, a carrying card bar pull hand motor, a carrying card bar pull hand screw, a carrying card bar pull hand guide rail and a carrying card bar pull hand horizontal slider assembly. The carrying card bar pull hand motor is connected to the carrying card bar pull hand screw, the carrying card bar pull hand screw is slidably connected to the carrying card bar pull hand horizontal slider assembly, and the carrying card bar pull hand horizontal slider assembly is slidably connected to the carrying card bar pull hand guide rail; the carrying card bar pull hand is fixedly connected to the carrying card bar pull hand horizontal slider assembly.

[0032] The sample card strip dial hand in the sample adding dial hand device is connected to the dial hand horizontal slider assembly. When horizontal movement is required, the dial hand translation motor is started, and the rotating shaft on the dial hand translation motor drives the dial hand horizontal transmission mechanism to move. The dial hand horizontal transmission mechanism drives the dial hand horizontal slider assembly to move along the dial hand translation guide rail, thereby driving the sample card strip dial hand to move along the dial hand translation guide rail; when it is necessary to move up and down, the dial hand lifting motor is started, and the dial hand upper and lower slider assemblies are driven to slide along the dial hand lifting guide rail through the dial hand lifting screw rod, thereby driving the sample card strip dial hand to move up and down, so as to realize the transfer of the reagent card strip from the sample rack loading table to the card strip fixing table of the carrier device.

[0033] The carrying card strip pusher of the carrying and pushing hand device is arranged at the rear of the card strip fixing platform, and its horizontal movement is completed by the cooperation of the carrying card strip pusher motor, the carrying card strip pusher screw, the carrying card strip pusher guide rail and the carrying card strip pusher horizontal slider assembly; when the carrying card strip pusher motor is started, the carrying card strip pusher horizontal slider assembly is driven to slide along the carrying card strip pusher guide rail through the carrying card strip pusher screw, thereby driving the carrying card strip pusher to move horizontally along the carrying card strip pusher guide rail, so as to realize the pushing of the reagent card strip from the card strip fixing platform to the sample inlet of the detection instrument.

[0034] As a preferred solution of the present invention, a card strip fixing spring is provided on the card strip fixing platform for fixing the reagent card strip on the card strip fixing platform.

[0035] As a preferred solution of the present invention, the translation transmission mechanism of the carrier device and the horizontal transmission mechanism of the sample adding and pulling hand device have the same structure, both of which include a driving wheel 1, a driven wheel 1 and a synchronous belt 1, and the synchronous belt is connected to the outer sides of the driving wheel 1 and the driven wheel 1. The driving wheel 1 is driven to rotate by the motor, and then the driven wheel 1 is driven to rotate by the synchronous belt 1, thereby realizing the transmission function.

[0036] The technical problem that the present invention also solves is to provide a method with reasonable design, controllable operation and continuous automatic sample addition.

[0037] In order to solve the above technical problems, the technical solution adopted by the present invention is: the automatic sample addition method specifically comprises the following steps:

[0038] (1) Turn on the power and wait for the automatic sampler to be initialized and ready;

[0039] (2) After the import test items are completed;

[0040] When in normal mode, place a sample rack with sample cups and reagent card strips of corresponding test items on the sample platform, click Start Test, and push the sample rack on the sample platform into the sample rack loading platform through the sample pusher; when emergency mode is needed, press the emergency button to start the emergency mode, place a sample rack with sample cups and reagent card strips of corresponding test items on the sample rack loading platform, and click Start Test;

[0041] If you need to switch to emergency mode in normal mode, press the emergency button. The injection platform will stop injecting samples. If there is an unprocessed sample rack on the sample rack stage, wait until the sample rack is processed and the reagent card enters the carrier. Then put the sample cup with the emergency sample, the diluent cup and the reagent card of the corresponding test item into the sample rack stage and click to start the test.

[0042] (3) The sample rack stage is driven by the stage motion assembly to move to the sample scanning position. The barcode of the sample cup is scanned by the sample scanner, and an information adding box pops up. After entering the information, click Submit.

[0043] (4) The reagent card barcode scanner scans the barcode of the reagent card and uploads it to the host computer;

[0044] (5) After the host computer confirms that the reagent card strip is correct, the sample adding device dilutes and mixes the sample in the sample cup in the sample rack through puncture sampling, and then adds the diluted and mixed sample to the reagent card strip; the sample adding device separates the reagent card strip and the sample rack;

[0045] (6) The sample rack is lowered and pushed to the disposal platform, and the reagent card strip is carried by the carrying device to the sample inlet of the matching detection instrument.

[0046] The emergency mode is activated after pressing the emergency button of the instrument. The automatic sample loading machine for assembly line detection can use the two modes separately, or the emergency mode can be temporarily used in the middle of the normal mode.

[0047] Compared with the prior art, the present invention has the following beneficial effects: through a series of motion devices such as a sample injection device, a sample rack stage device, a puncture sampling needle device, a disposal device, a hand-operated device, and a transport device, the entire automatic sample injection process is realized, continuous automatic sample addition is realized, and streamlined operation is realized, thereby improving detection efficiency; the automatic sample injector is fully automated, automatically adapts to various types of detection instruments according to the detection items, reduces pollution caused by human operation, and the operation is controllable, while reducing costs, and is suitable for wide promotion. BRIEF DESCRIPTION OF THE DRAWINGS

[0048] The following is further described in detail with reference to the accompanying drawings and embodiments of the present invention:

[0049] Figure 1 It is a schematic structural diagram of a sample loading platform with a sample rack in the overall structure of the sample loading device of the present invention;

[0050] Figure 2 It is a schematic diagram of the structure without a sample rack on the sample loading platform in the overall structure of the sample loading device of the present invention;

[0051] Figure 3 It is a schematic structural diagram of a sample rack on a sample rack stage in the overall structure of the sample adding device of the present invention;

[0052] Figure 4 It is a schematic structural diagram of the overall structure of the sample adding device of the present invention from one side of the sample introduction platform;

[0053] Figure 5 It is a partial top view of the sample adding device of the present invention;

[0054] Figure 6 It is a structural schematic diagram of the stage motion assembly of the sample loading device of the present invention;

[0055] Figure 7 It is a schematic cross-sectional structural diagram of a stage limiting device of a sample loading device of the present invention;

[0056] Figure 8 It is a partially enlarged structural diagram of the puncture sampling needle translation assembly in the sample adding device of the present invention;

[0057] Fig. 9 It is a partial enlarged structural diagram of the puncture sampling needle lifting assembly in the sample adding device of the present invention;

[0058] Fig.10 It is a partial enlarged structural diagram of the discard pusher in the sample adding device of the present invention;

[0059] Fig.11 It is the overall structure diagram of the automatic sample adding machine for pipeline detection of the present invention;

[0060] Fig.12 It is a partial enlarged structural diagram of the sample adding and dialing device of the sample adding device of the present invention;

[0061] Fig.13 It is a partial enlarged structural diagram of the up-and-down moving components of the carrier device of the present invention;

[0062] Fig.14 is a rear partial enlarged view of the up-and-down moving assembly of the carrier device of the present invention;

[0063] Fig.15 is a partial enlarged view of the horizontal translation assembly of the carrier device of the present invention;

[0064] Fig.16 It is an overall structural diagram of the carrier device of the automatic sample loading machine of the present invention;

[0065] Fig.17 It is a structural diagram of the card strip fixing platform of the present invention;

[0066] Among them: 1-sample rack; 101-sample cup; 102-dilution cup one; 103-dilution cup two; 2-puncture sampling needle; 3-sampling needle lifting assembly; 301-sampling needle lifting motor; 302-sampling needle lifting screw; 303-sampling needle lifting slider assembly; 304-sampling needle lifting guide rail; 305-motor fixing block; 4-sampling needle translation assembly; 401-sampling needle translation motor; 402-sampling needle driving wheel; 403-sampling needle driven wheel; 404-sampling synchronous belt; 405-sampling needle horizontal slider assembly; 406-sampling needle horizontal guide rail; 407-fixed vertical block; 5-sample rack stage; 501-stage lifting assembly; 5011-stage lifting motor; 5012-stage lifting Screw rod; 5013- stage slider assembly 1; 5014- stage lifting rail; 502- stage translation assembly; 5021- stage translation motor; 5022- translation driving wheel; 5023- translation driven wheel; 5024- stage slider assembly 2; 5025- stage translation rail; 5026- translation synchronous belt; 503- stage limit device; 5031- spring; 5032- inclined block; 5033- sample rack stopper; 504- sample rack hook; 6- card bar fixing table; 601- card bar fixing spring; 7- carrier; 701- horizontal translation assembly; 7011- translation rail; 7012- translation motor; 7013- translation transmission mechanism; 70131- translation driving wheel 1; 70 132-translation driven wheel 1; 70133-translation synchronous belt 1; 7014-translation slider assembly; 702-up and down moving assembly; 7021-lifting motor; 7022-lifting guide rail; 7023-lifting screw rod; 7024-slider assembly 1; 7025-card bar fixing table up and down movement fixed block; 8-carrying and dialing hand device; 801-carrying card bar dialing hand; 802-carrying card bar dialing hand translation guide rail; 803-carrying card bar dialing hand motor; 9-sample adding and dialing hand device; 901-sample adding and dialing hand card bar; 9011-sample adding and dialing bar fixing block; 902-hand horizontal slider assembly; 903-hand translation guide rail; 904-hand lifting guide rail; 905-hand translation motor; 906-hand lifting motor; 907-dial Hand horizontal transmission mechanism; 9071-hand driving wheel one; 9072-hand driven wheel one; 9073-hand synchronous belt one; 908-hand lifting screw rod; 909-hand upper and lower slider assembly; 10-discarding push handle; 1001-discarding push handle motor; 1002-push handle slider; 1003-push handle guide rail; 1004-push handle; 1005-screw rod two; 11-discarding platform; 1201-sample scanner; 1202-reagent card bar scanner; 13-cleaning device; 1301-cleaning liquid side inlet; 1302-cleaning liquid outlet; 1303-cleaning tank; 14-bottom plate; 15-first baffle plate; 16-second baffle plate; 17-reagent card strip; 18-adapting instrument placement platform; 19-injection push handle device;1901-motor 1; 1902-screw rod 1; 1903-slider assembly; 1904-injection guide rail; 1905-injection push handle; 20-injection platform; 21-waste liquid pump. ; DETAILED DESCRIPTION

[0067] In order to better illustrate the technical solution of the present invention, the technical solution of the present invention is further described in detail in conjunction with the accompanying drawings and embodiments.

[0068] Example 1: Figures 1 to 10 As shown, the sample loading device includes a puncture sampling needle 2 and a sample loading platform 20, wherein the puncture sampling needle 2 is arranged on one side of the sample rack 1 for sucking the sample on the sample rack 1 and diluting and mixing the sample and then adding the sample to the sample loading hole of the reagent card strip 17; the sample loading platform 20 is arranged on the other side of the sample rack 1, and the sample loading platform 20 is used to store the sample rack 1; the sample loading platform 20 automatically pushes the sample rack 1 into the sample loading device through the sample loading pusher device 19; the sample loading device also includes a sample rack stage 5 for placing the sample rack 1; the sample rack stage 5 realizes up and down and translational movement through the stage motion component; the sample loading platform 20 is arranged on one side of the sample rack stage 5, and the sample loading platform 20 is used to place multiple sample racks 1, and the sample loading pusher device pushes the sample rack 1 placed in the sample loading platform 20 into the sample rack stage 5; the sample loading pusher device 19 includes a motor 1 901, screw rod 1902, slider assembly 1903, injection guide rail 1904 and injection pusher 1905, one end of the screw rod 1902 is connected to the motor 1901, and the other end is slidably connected to the slider assembly 1903; one side of the slider assembly 1903 is connected to the injection guide rail 1904, and the slider assembly 1903 moves linearly along the injection guide rail 1904, and the other side of the slider assembly 1903 is connected to the injection pusher 1905; the motor 1901 is started to drive the screw rod 1902 to rotate, the screw rod 1902 is slidably connected to the slider assembly 1903, the screw rod 1902 drives the slider assembly 1903 to move linearly along the injection guide rail 1904, and the injection pusher 1905 is connected to the slider assembly 1903, thereby driving the injection pusher 1905 to move, so as to realize the movement of the sample rack 1 by the injection pusher 1905;

[0069] The sample adding device also includes a sampling needle lifting component 3 and a sampling needle translation component 4, wherein the sampling needle lifting component 3 is used to control the up and down movement of the puncture sampling needle 1, and the sampling needle translation component 4 is used to control the horizontal translation movement of the puncture sampling needle 1; the sampling needle lifting component 3 includes a sampling needle lifting guide rail 304, a sampling needle lifting screw rod 302, a sampling needle lifting motor 301 and a sampling needle lifting slider component 303, wherein the sampling needle lifting motor 301 is connected to the sampling needle lifting screw rod 302, the sampling needle lifting slider component 303 is slidably connected to the sampling needle lifting screw rod 302, and the sampling needle lifting slider component 303 is connected to the sampling needle lifting guide rail 304, and the puncture sampling needle 1 is sleeved in the The sampling needle lifting slider assembly 303; the up and down movement of the puncture sampling needle 2 is achieved by the cooperation of the sampling needle lifting motor 301, the sampling needle lifting screw 302, the sampling needle lifting slider assembly 303, and the sampling needle lifting guide rail 304; the sampling needle translation assembly 4 includes a sampling needle translation motor 401, a sampling needle driving wheel 402, a sampling needle driven wheel 403, a sampling needle timing belt 404, a sampling needle horizontal slider assembly 405 and a sampling needle horizontal guide rail 406, the sampling needle translation motor 401 is connected to the sampling needle driving wheel 402, the sampling needle timing belt 404 is connected to the sampling needle driving wheel 402 and the sampling needle driven wheel 403, and the sampling needle horizontal slider assembly 405 is connected to the sampling needle timing belt 404 , and the sampling needle horizontal slider assembly 405 is slidably connected to the sampling needle horizontal guide rail 406; the sampling needle horizontal slider assembly 405 is fixedly connected to the sampling needle lifting guide rail 304 and the sampling needle lifting motor 301; the sampling needle horizontal slider assembly 405 includes an upper fixed vertical block 407, and the sampling needle lifting motor 301 is fixedly connected to the fixed vertical block 407 of the sampling needle horizontal slider assembly 405 through the motor fixed block 305; a sample cup 101, a dilution cup 102 and a dilution cup 2 103 and a corresponding reagent card strip 17 are placed on the sample rack 1, and the reagent card strip 17 is placed at the end of the sample rack 1; the puncture sampling needle 2 absorbs the sample in the sample cup 101 and adds it to the dilution cup , and then absorb the sample in the diluent cup and add it to the reagent card strip 17; the sampling needle lifting component 3 is used to control the up and down movement of the puncture sampling needle 2, and the sampling needle translation component 4 is used to control the horizontal translation movement of the puncture sampling needle 2, so that the puncture sampling needle 2 automatically moves up and down to enter the sample cup 101 and the diluent cup 1 102 and the diluent cup 2 103 to absorb the sample, and moves horizontally with the absorbed sample to the position of the sample cup 101 and the diluent cup 1 102 and the diluent cup 2 103 and the reagent card strip 17 and other positions; the sample rack 1 is placed on the sample rack stage 5, and the sample rack stage 5 realizes up and down and translation movement through the stage movement component; and then the sample rack 1 placed thereon is driven by the sample rack stage 5 to realize up and down and translation movement;The stage motion assembly includes a stage lifting assembly 501 and a stage translation assembly 502. The stage lifting assembly 501 includes a stage lifting motor 5011, a stage lifting screw rod 5012, a stage slider assembly 1 5013 and a stage lifting guide rail 5014. The stage lifting motor 5011 is connected to the stage slider assembly 1 5013 through the stage lifting screw rod 5012. One end of the stage slider assembly 1 5013 is connected to the stage lifting guide rail 5014, and the other end of the stage slider assembly 1 5013 is fixedly connected to the sample rack stage 5; the stage lifting motor 5011 drives the stage slider through the stage lifting screw rod 5012 Component 1 5013 moves up and down along the stage lifting guide rail 5014, thereby driving the sample rack stage 5 to move up and down along the stage lifting guide rail 5014; the stage translation component 502 includes a stage translation motor 5021, a translation driving wheel 5022, a translation driven wheel 5023, a stage slider component 2 5024 and a stage translation guide rail 5025, the stage translation motor 5021 is connected to the translation driving wheel 5022, the translation driving wheel 5022 is connected to the translation driven wheel 5023 through a translation synchronous belt 5026, the stage translation guide rail 5025 is arranged below the translation synchronous belt 5026, and is connected to the translation synchronous belt 5026 through the stage slider component 2 5024. The stage slider assembly 2 5024 is connected to the stage translation guide rail 5025 through the translation synchronous belt 5026, and the stage translation motor 5021 drives the stage slider assembly 2 5024 to move horizontally along the stage translation guide rail 5025, thereby driving the sample rack stage 5 to move horizontally along the stage translation guide rail 5025; the stage lifting motor 5011 and the stage lifting guide rail 5014 are all fixed on the stage slider assembly 2 5024; when horizontal movement is required, the stage translation motor 5021 is started, and the translation driving wheel 5022 and the translation driven wheel 5023 drive the stage slider assembly 2 5024 connected thereto through the translation synchronous belt 5026. Movement, the stage slider assembly 2 5024 is slidably connected to the stage translation guide rail 5025, and the stage slider assembly 2 5024 is fixedly connected to the sample rack stage 5, so the sample rack stage 5 follows the stage slider assembly 2 5024 to perform horizontal translation movement along the stage translation guide rail 5025; when it is necessary to move up and down, the stage lifting motor 5011 is started, and the stage lifting screw rod 5012 drives the stage slider assembly 1 5013 to move, and the stage slider assembly 1 5013 is slidably connected to the stage lifting guide rail 5014, and the stage slider assembly 1 5013 is fixedly connected to the sample rack stage 5, so the sample rack stage 5 follows the stage slider assembly 1 5013 to move up and down along the stage lifting guide rail 5014;

[0070] The stage motion assembly also includes a stage limiting device 503 and a sample rack hook 504. The stage limiting device 503 includes a spring 5031, an inclined block 5032 and a sample rack stopper 5033. The spring 5031 is arranged below the inclined block 5032. The sample rack stopper 5033 is arranged at the front end of the stage limiting device 503. The sample rack hook 504 is arranged at the front end of the sample rack 1. When the sample rack hook 504 reaches the middle position between the stage limiting device 503 and the sample rack stopper 5033, the spring 5031 of the stage limiting device 503 moves the inclined block 5032. 2 pops out, thereby limiting the sample rack 1 from continuing to move forward on the sample rack stage 5; a sample rack hook 504 is provided at the front end of the sample rack 1, and a sample rack stopper 5033 is provided at the front end of the stage limiting device 503. When the sample rack hook 504 reaches the middle position between the stage limiting device 503 and the sample rack stopper 5033, the spring 5031 of the stage limiting device 503 pops out the inclined block 5032, thereby limiting the sample rack 1 from continuing to move forward on the sample rack stage 5; the sample rack hook 504 has no limiting effect on the lateral movement of the sample rack to the discarding platform 11, and only has a limiting effect on the forward and backward movement of the sample rack 1;

[0071] The automatic sample loading machine also includes a discarding pusher 10 and a discarding platform 11, wherein the discarding platform 11 is arranged on one side of the sample rack stage 5 and the discarding pusher 10 is arranged on the other side of the sample rack stage 5, and the discarding pusher 10 is used to push the sample rack 1 into the discarding platform 10 for temporary storage; the discarding pusher 10 includes a discarding pusher motor 1001, a pusher slider 1002, a pusher guide rail 1003 and a pusher 1004, wherein the discarding pusher motor 1001 is connected to the pusher slider 1002 via a screw rod 1005, and the pusher guide rail 1003 is connected to the pusher slider 1002 via a screw rod 1005. The hand slider 1002 is slidably connected to the push handle guide rail 1003 and moves along the push handle slide rail 1003; the push handle slider 1002 is fixedly connected to the push handle 1004; the discard push handle motor 1001 is started, and the screw rod 1005 drives the push handle slider 1002 to move along the push handle guide rail 1003, the push handle slider 1002 is slidably connected to the push handle guide rail 1003, and the push handle slider 1002 is fixedly connected to the push handle 1004, so that the push handle 1004 moves along the push handle guide rail 1003, and the sample rack 1 is pushed into the discard platform 11 for temporary storage.

[0072] The automatic sample loading machine further comprises a bottom plate 14, a first baffle 15 and a second baffle 16, wherein the first baffle 15 and the second baffle 16 are arranged in parallel and are both vertically connected to the bottom plate 14, the sample rack stage 5 is arranged between the first baffle 15 and the second baffle 16, the sampling needle lifting assembly 3 and the sampling needle translation assembly 4 are arranged on the outside of the first baffle 15; the discarding pusher 10 is arranged on a side of the first baffle 15 away from the second baffle 16, and the discarding platform 11 and the injection platform 20 are both arranged on a side of the second baffle 16 away from the first baffle 15; and The sample injection platform 20 and the disposal platform 11 are both vertically connected to the second baffle 16, and the sample injection platform 20 is arranged above the disposal platform 11; wherein the sample rack stage 5 is arranged between the first baffle 15 and the second baffle 16, and the stage motion assembly is arranged on the outside of the first baffle 15; the sample injection platform 20 and the disposal platform 11 are both open box-type platforms, which can accommodate at most 3 sample racks 1 for temporary storage; a controller, at least one interface and a waste liquid pump 21 are arranged on the side of the bottom plate 14, which are used to connect the sample loading device with the outside and control the operation of the sample loading device;

[0073] The sample loading device also includes a scanner, which includes a sample scanner 1201 and a reagent card barcode scanner 1202. The sample scanner 1201 is arranged at a position corresponding to the sample rack stage 5 on the same side of the first baffle 15 and the stage translation assembly 502, and is used to scan the barcode on the sample cup 101 placed in the sample rack 1 and enter information; the reagent card barcode scanner 1202 is arranged on the sampling needle horizontal slider assembly 405, and is used to scan the reagent card strip 17 placed on the sample rack 1 to confirm whether the item of the reagent card strip 17 is the item that the sample needs to be tested.

[0074] The automatic loading machine also includes a cleaning device, which is arranged below the puncture sampling needle 2 and is used to clean the puncture sampling needle 2 after sampling. After the puncture sampling needle 2 has finished diluting the sample, it needs to move into the cleaning device 13 to clean the inside and outside of the puncture sampling needle 2 so as to absorb other samples later, thereby ensuring that the test sample is not contaminated; the cleaning device 13 includes a cleaning liquid inlet system, a drainage system, a cleaning liquid side inlet 1301, a cleaning liquid outlet 1302 and a cleaning pool 1303, the cleaning liquid inlet system controls the entry of the cleaning liquid, the cleaning liquid side inlet 1301 is arranged on the side of the cleaning pool 1303, the cleaning liquid outlet 1302 is arranged at the bottom of the cleaning pool 1303, and the drainage system controls the discharge of the cleaning liquid and is connected to the cleaning liquid outlet 1302; the cleaning device 13 is arranged between the first baffle 15 and the second baffle 16, fixedly connected to the second baffle 16, and arranged on one side of the sample rack stage 5. After the puncture sampling needle 2 completes sample dilution, it moves into the cleaning tank 1303 to clean the inside and outside of the puncture sampling needle 2. The cleaning liquid enters from the cleaning liquid side inlet 1301 for cleaning. The cleaning liquid outlet 1302 is connected to the drainage system, and the waste liquid after cleaning is discharged from the lower cleaning liquid outlet through the drainage system.

[0075] Example 2: Figures 10 to 17As shown, the automatic sample loading machine for assembly line detection includes an adapter instrument placement platform 18 for placing at least one detection instrument, a carrier device 7 and a sample loading device, the adapter instrument placement platform and the sample loading device are respectively connected to the carrier device 7, and the reagent card strip 17 is transferred to the detection instrument on the adapter instrument placement platform 18 by the movement of the carrier device 7; the adapter instrument placement platform 18 is used to place multiple detection instruments, preferably 1-3 detection instruments, and more instruments can be adapted according to detection needs. According to the detection items, the reagent card strip 17 is automatically transported by the carrier device 7 to the corresponding detection instrument for detection, such as a fluorescent immunoassay analyzer, a biochemical analyzer, a chemiluminescence analyzer, etc.; the sample loading device is provided with a sample loading hand device 9, and the carrier device 7 is provided with a card strip fixing table 6 and a carrier hand device 8; the card strip fixing table 6 and the sample rack 1 are on the same horizontal plane, and the reagent card strip 17 is transferred from the sample rack to the sample rack by the sample loading hand device 9 1 is moved to the card strip fixing platform 6 of the carrier 7, so that the reagent card strip 17 is carried to the detection instrument on the adapter instrument placement platform 18 by the carrier 7, and then the reagent card strip 17 is pushed to the injection port of the detection instrument for detection by the carrier hand device 8; the carrier 7 also includes an up and down moving component 702 and a horizontal translation component 701, the up and down moving component 702 includes a lifting motor 7021, a lifting guide rail 7022, a lifting screw rod 7023, a slider component 1 7024 and a card strip fixing platform up and down moving fixed block 7025, the lifting motor 7021 is connected to one end of the lifting screw rod 7023, the other end of the lifting screw rod 7023 is connected to one end of the slider component 1 7024, and the other end of the slider component 1 7024 is slidably connected to the lifting guide rail 7022; the card strip fixing platform up and down moving fixed block 7025 is connected to the slider component 1 7024;

[0076] The horizontal translation assembly 701 includes a translation guide rail 7011, a translation motor 7012, a translation transmission mechanism 7013 and a translation slider assembly 7014. The translation motor 7011 is connected to the translation transmission mechanism 7013. The translation transmission mechanism 7013 is connected to the translation guide rail 7011 through the translation slider assembly 7014 and enables the translation slider assembly 7014 to move horizontally on the translation guide rail 7011. The clamping bar fixing platform 6 is connected to the clamping bar fixing platform up and down movement fixed block 7025; the translation slider assembly 7014 is connected to the up and down moving assembly 702; the translation transmission mechanism 7013 includes a translation driving wheel 70131, a translation driven wheel 70132 and a translation synchronous belt 70133. 0133, the translation synchronous belt 70133 is sleeved on the outer sides of the translation active wheel 70131 and the translation driven wheel 70132; the card strip fixing platform 6 is provided with a card strip fixing spring piece 601, which is used to fix the reagent card strip 17 on the card strip fixing platform 6; the reagent card strip 17 is pushed onto the carrier device 7, that is, onto the card strip fixing platform 6 by the sample adding and dialing device 9, and is pressed by the card strip fixing spring piece 601, the card strip fixing platform 6 and the sample rack 1 are in the same horizontal plane, and the carrier dialing device 8 is behind the card strip fixing platform 6. At this time, the carrier device 7 moves, and can move up and down and horizontally according to the position of the adapted detection instrument, so as to accurately reach the position of the sample inlet of the detection instrument, and then the reagent card strip 17 is pushed into the sample inlet of the detection instrument by the carrier dialing device 8;

[0077] The sample adding and dialing hand device 9 comprises a sample adding and card strip dialing hand 901, a dialing hand horizontal slider assembly 902, a dialing hand translation guide rail 903, a dialing hand lifting guide rail 904, a dialing hand translation motor 905, a dialing hand lifting motor 906, a dialing hand lifting screw rod 908, a dialing hand horizontal transmission mechanism 907 and a dialing hand upper and lower slider assembly 909, wherein the dialing hand translation motor 905 is connected to the dialing hand horizontal transmission mechanism 907, the dialing hand horizontal slider assembly 902 is fixed on the dialing hand horizontal transmission mechanism 907, the dialing hand horizontal slider assembly 902 is slidably connected to the dialing hand translation guide rail 903, the sample adding and card strip dialing hand 901 is connected to the dialing hand horizontal slider assembly 902; at the same time, the dialing hand horizontal slider assembly 902 is connected to the dialing hand lifting screw rod 908, and the dialing hand horizontal transmission mechanism 907 is connected to the dialing hand lifting screw rod 908. The lowering motor 906 is fixedly connected to the dial hand lifting guide rail 904; the dial hand lifting motor 906 is connected to the dial hand lifting screw rod 908, the dial hand lifting screw rod 908 is connected to the dial hand upper and lower slider assembly 909, the dial hand upper and lower slider assembly 909 is slidably connected to the dial hand lifting guide rail 904, and the dial hand upper and lower slider assembly 909 is fixedly connected to the sample card strip dial hand 901 through the sample card strip fixing block 9011; the dial hand horizontal transmission mechanism 907 includes a dial hand driving wheel 9071, a dial hand driven wheel 9072 and a dial hand synchronous belt 9073, and the dial hand synchronous belt 9073 is sleeved on the outer sides of the dial hand driving wheel 9071 and the dial hand driven wheel 9072;

[0078] The carrying and pulling hand device 8 includes a carrying card bar pull hand 801, a carrying card bar pull hand motor 803, a carrying card bar pull hand screw, a carrying card bar pull hand guide rail 802 and a carrying card bar pull hand horizontal slider assembly. The carrying card bar pull hand motor 803 is connected to the carrying card bar pull hand screw, the carrying card bar pull hand screw is slidably connected to the carrying card bar pull hand horizontal slider assembly, and the carrying card bar pull hand horizontal slider assembly is slidably connected to the carrying card bar pull hand guide rail 802; the carrying card bar pull hand 801 is fixedly connected to the carrying card bar pull hand horizontal slider assembly.

[0079] The sample card strip dial hand 901 in the sample adding dial hand device 9 is connected to the dial hand horizontal slider assembly 902. When horizontal movement is required, the dial hand translation motor 905 is started, driving the rotating shaft on the dial hand translation motor 905 to drive the dial hand horizontal transmission mechanism 907 to move, and the dial hand horizontal transmission mechanism 907 drives the dial hand horizontal slider assembly 902 to move along the dial hand translation guide rail 903, thereby driving the sample card strip dial hand 901 to move along the dial hand translation guide rail 903; when it is necessary to move up and down, the dial hand lifting motor 906 is started, and the dial hand upper and lower slider assembly 909 is driven to slide along the dial hand lifting guide rail 904 through the dial hand lifting screw rod 908, thereby driving the sample card strip dial hand 901 to move up and down, so as to realize the transfer of the reagent card strip 17 from the sample rack loading platform 5 to the card strip fixing platform 6 of the carrier 7.

[0080] The carrying card strip pusher 801 of the carrying card strip pusher device 8 is arranged at the rear of the card strip fixing platform 6, and its horizontal movement is completed by the cooperation of the carrying card strip pusher motor 803, the carrying card strip pusher screw, the carrying card strip pusher guide rail 802 and the carrying card strip pusher horizontal slider assembly; when the carrying card strip pusher motor 803 is started, the carrying card strip pusher screw drives the carrying card strip pusher horizontal slider assembly to slide along the carrying card strip pusher guide rail 802, thereby driving the carrying card strip pusher 801 to move horizontally along the carrying card strip pusher guide rail 802, so as to realize the pushing of the reagent card strip 17 from the card strip fixing platform 6 to the sample inlet of the detection instrument; wherein, the other specific structures of the sample loading device are the same as those in Example 1.

[0081] Embodiment 3: The automatic sample addition method specifically comprises the following steps:

[0082] (1) Turn on the power and wait for the automatic sampler to be initialized and ready;

[0083] (2) After the test items are imported, when in normal mode, place the sample rack 1 with the sample cup 101, the diluent cup 1 102, the diluent cup 2 103 and the reagent card strip 17 of the corresponding test items on the sample injection platform 20, and click to start the test; push the sample rack 1 on the sample injection platform 20 into the sample rack stage 5 by the sample injection pusher 19;

[0084] When the emergency mode is needed, press the emergency button to start the emergency mode, place the sample rack 1 with the sample cup 101 and the reagent card strip 17 of the corresponding test item on the sample rack stage 5, and click to start the test;

[0085] If the emergency mode needs to be switched from the normal mode, the emergency button is also pressed, and the sample injection platform 20 stops injecting samples. If there is an unprocessed sample rack 1 on the sample rack stage 5, wait until the sample rack 1 is processed and the reagent card strip 17 enters the carrier 7, then put the sample cup 101 with the emergency sample, the diluent cup 1 102 and the diluent cup 2 103 and the reagent card strip 17 of the corresponding test item into the sample rack stage 5, and click to start testing;

[0086] (3) The sample rack stage 5 is driven by the stage motion assembly to move to the sample scanning position, and the barcode of the sample cup 101 is scanned by the sample scanner 1201, and an information adding box pops up. After entering the information, click Submit;

[0087] (4) The reagent card barcode scanner 1202 scans the barcode of the reagent card strip 17 and uploads it to the host computer;

[0088] (5) After the host computer confirms that the reagent card strip 17 is correct, the sample loading device dilutes and mixes the sample in the sample cup 101 in the sample rack 1 through the puncture sampling needle 2, and then loads the diluted and mixed sample into the reagent card strip 17; the sample loading device separates the reagent card strip 17 from the sample rack 1; (6) The sample rack 1 is lowered and pushed to the disposal platform 11, and the reagent card strip 17 is transferred to the transport device 7 and transported to the sample inlet of the matching detection instrument.

[0089] The above shows and describes the basic principles, main features and advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention to be protected. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A sample adding device, comprising a puncture sampling needle, characterized in that: It also includes a sampling platform, which is used to store the sample rack, and the sampling platform automatically pushes the sample rack into the sampling device through the sampling pusher device; the sampling device also includes a sampling needle lifting component and a sampling needle translation component, the sampling needle lifting component is used to control the up and down movement of the puncture sampling needle, and the sampling needle translation component is used to control the horizontal translation movement of the puncture sampling needle; The sample loading device also includes a sample rack stage for placing the sample rack; the sample rack stage realizes up and down and translational motion through a stage motion assembly; the sample injection pusher device includes a motor 1, a screw rod 1, a slider assembly, a sample injection guide rail and a sample injection pusher, one end of the screw rod 1 is connected to the motor 1, and the other end is slidably connected to the slider assembly; the slider assembly is connected to the sample injection guide rail, and the slider assembly moves linearly along the sample injection guide rail, and the slider assembly is also connected to the sample injection pusher; The sampling needle lifting assembly includes a sampling needle lifting guide rail, a sampling needle lifting screw rod, a sampling needle lifting motor and a sampling needle lifting slider assembly. The sampling needle lifting motor is connected to the sampling needle lifting screw rod. The sampling needle lifting slider assembly is slidably connected to the sampling needle lifting screw rod, and the sampling needle lifting slider assembly is connected to the sampling needle lifting guide rail. The puncture sampling needle is sleeved on the sampling needle lifting slider assembly. At least one sample cup and / or diluent cup and a corresponding reagent card strip are placed on the sample rack, and the reagent card strip is placed at the end of the sample rack; the puncture sampling needle draws the sample in the sample cup and adds it to the diluent cup, and then draws the sample in the diluent cup and adds it to the sample adding hole of the reagent card strip; The stage motion assembly includes a stage lifting assembly and a stage translation assembly, the stage lifting assembly includes a stage lifting motor, a stage lifting screw, a stage slider assembly 1 and a stage lifting guide rail, the stage lifting motor is connected to the stage slider assembly 1 through the stage lifting screw, one end of the stage slider assembly 1 is connected to the stage lifting guide rail, and the other end of the stage slider assembly 1 is fixedly connected to the sample rack stage; the stage lifting motor drives the stage slider assembly 1 to move up and down along the stage lifting guide rail through the stage lifting screw, thereby driving the sample rack stage to move up and down along the stage lifting guide rail; the stage translation assembly includes a stage translation motor, a translation active The present invention relates to a method for producing a sample rack carrier, wherein the first and second carriers are provided with a plurality of movable carriers, wherein the movable carrier is provided with a plurality of movable carriers and a plurality of movable carriers. The movable carrier is provided with a plurality of movable carriers and a plurality of movable carriers. The movable carrier is provided with a plurality of movable carriers and a plurality of movable carriers. The movable carrier is provided with a plurality of movable carriers and a plurality of movable carriers.

2. The sample adding device according to claim 1, characterized in that: The sample introduction platform is arranged on one side of the sample rack stage, and the sample introduction platform is used to place a plurality of sample racks. The sample introduction pusher device pushes the sample rack placed in the sample introduction platform into the sample rack stage.

3. The sample adding device according to claim 2, characterized in that: The sampling needle translation assembly includes a sampling needle translation motor, a sampling needle driving wheel, a sampling needle driven wheel, a sampling needle timing belt, a sampling needle horizontal slider assembly and a sampling needle horizontal guide rail. The sampling needle translation motor is connected to the sampling needle driving wheel, the sampling needle timing belt is sleeved on the sampling needle driving wheel and the sampling needle driven wheel, the sampling needle horizontal slider assembly is connected to the sampling needle timing belt, and the sampling needle horizontal slider assembly is slidably connected to the sampling needle horizontal guide rail; the sampling needle horizontal slider assembly is fixedly connected to the sampling needle lifting guide rail and the sampling needle lifting motor.

4. The sample adding device according to claim 1, characterized in that: The sample loading device also includes a discarding pusher and a discarding platform, wherein the discarding platform is arranged on one side of the sample rack stage and the discarding pusher is arranged on the other side of the sample rack stage, and the discarding pusher is used to push the sample rack into the discarding platform for temporary storage; the discarding pusher includes a discarding pusher motor, a pusher slider assembly, a pusher guide rail and a pusher, the discarding pusher motor is connected to the pusher slider assembly through a second screw rod, the pusher slider is slidably connected to the pusher guide rail and moves along the pusher guide rail; the pusher slider assembly is fixedly connected to the pusher.

5. The sample adding device according to claim 1, characterized in that: The sample adding device also includes a cleaning device, which is arranged below the puncture sampling needle and is used for cleaning the puncture sampling needle.

6. The sample adding device according to claim 1, characterized in that: The stage motion assembly also includes a stage limiting device and a sample rack hook. The stage limiting device includes a spring, an inclined block and a sample rack stopper. The spring is arranged below the inclined block, the sample rack stopper is arranged at the front end of the stage limiting device, and the sample rack hook is arranged at the front end of the sample rack. When the sample rack hook reaches the middle position between the stage limiting device and the sample rack stopper, the spring of the stage limiting device pops out the inclined block, thereby limiting the sample rack from continuing to move forward on the sample rack stage.

7. The sample adding device according to claim 2, characterized in that: The sample loading device also includes a base plate, a first baffle plate and a second baffle plate. The first baffle plate and the second baffle plate are arranged in parallel and are both vertically connected to the base plate. The sample rack stage is arranged between the first baffle plate and the second baffle plate. The sampling needle lifting assembly and the sampling needle translation assembly are arranged on the outside of the first baffle plate.

8. The sample adding device according to claim 7, characterized in that: The sample loading device also includes a scanner, which includes a sample scanner and a reagent card barcode scanner. The sample scanner is arranged at a position corresponding to the sample rack stage on the same side of the first baffle and the stage translation assembly, and is used to scan the barcode on the sample cup placed in the sample rack and enter information; the reagent card barcode scanner is arranged on the sampling needle horizontal slider assembly, and is used to scan the reagent card strip placed on the sample rack to confirm whether the item on the reagent card strip is the item that needs to be tested for the sample.

9. The sample adding device according to claim 7, characterized in that: The cleaning device comprises a cleaning liquid inlet system, a drainage system, a cleaning liquid side inlet, a cleaning liquid outlet and a cleaning tank, wherein the cleaning liquid inlet system controls the entry of the cleaning liquid; the cleaning liquid side inlet is arranged on the side of the cleaning tank, the cleaning liquid outlet is arranged at the bottom of the cleaning tank, the drainage system controls the discharge of the cleaning liquid and is connected to the cleaning liquid outlet; the cleaning device is arranged between the first baffle plate and the second baffle plate, fixedly connected to the second baffle plate, and arranged on one side of the sample rack stage.

10. The sample adding device according to claim 7, characterized in that: The discard pusher is arranged on the side of the first baffle away from the second baffle, the discard platform and the injection platform are both arranged on the side of the second baffle away from the first baffle, and the injection platform and the discard platform are both vertically connected to the second baffle, and the injection platform is arranged above the discard platform; wherein the stage guide rail is arranged between the first baffle and the second baffle, and the stage motion assembly is arranged on the outer side of the first baffle.

11. The sample adding device according to claim 3, characterized in that: The sample injection platform and the disposal platform are both open box-type platforms, which can accommodate up to 3 sample racks for temporary storage.

12. The sample adding device according to claim 7, characterized in that: A controller and at least one interface are arranged on the side of the bottom plate, which are used to connect the sample adding device with the outside and control the operation of the sample adding device.

13. An automatic sample loading machine for pipeline detection using the sample loading device according to any one of claims 1 to 12, characterized in that: It includes an adaptor placement platform for placing at least one detection instrument, a carrier and a sample loading device, wherein the adaptor placement platform and the sample loading device are respectively connected to the carrier, and the reagent card strip is transferred to the detection instrument on the adaptor placement platform by the movement of the carrier; The sample loading device is provided with a sample loading hand device, and the transport device is provided with a card strip fixing platform and a transport hand device; the card strip fixing platform and the sample rack are on the same horizontal plane, and the sample loading hand device moves the reagent card strip in the sample rack from the sample rack to the card strip fixing platform of the transport device, thereby transporting the reagent card strip to the detection instrument on the matching instrument placement platform through the transport hand device, and then the reagent card strip is pushed into the sample inlet of the detection instrument for detection through the transport hand device; The carrier device also includes an up-and-down moving assembly and a horizontal translation assembly, wherein the up-and-down moving assembly includes a lifting motor, a lifting guide rail, a lifting screw rod, a slider assembly 1 and a fixing block for the up-and-down movement of a clamping bar fixing platform, wherein the lifting motor is connected to one end of the lifting screw rod, the other end of the lifting screw rod is connected to the slider assembly 1, and the slider assembly 1 is slidably connected to the lifting guide rail; the fixing block for the up-and-down movement of the clamping bar fixing platform is connected to the slider assembly 1; The horizontal translation assembly includes a translation guide rail, a translation motor, a translation transmission mechanism and a translation slider assembly. The translation motor is connected to the translation transmission mechanism, and the translation transmission mechanism is connected to the translation slider assembly and drives it to move horizontally on the translation guide rail. The card bar fixing platform is connected to the card bar fixing platform's up and down moving fixed block; the translation slider assembly is connected to the up and down moving assembly.

14. The automatic sample loading machine for pipeline detection according to claim 13, characterized in that: The sample adding hand device comprises a sample adding card strip hand, a hand horizontal slider assembly, a hand translation guide rail, a hand lifting guide rail, a hand translation motor, a hand lifting motor, a hand lifting screw rod, a hand horizontal transmission mechanism and a hand upper and lower slider assembly, the hand translation motor is connected to the hand horizontal transmission mechanism, the hand horizontal slider assembly is fixed on the hand horizontal transmission mechanism, the hand horizontal slider assembly is slidably connected to the hand translation guide rail and moves along the hand translation guide rail, and the sample adding card strip hand is connected to the hand horizontal slider assembly; at the same time, the hand horizontal slider assembly is fixedly connected to the hand lifting motor and the hand lifting guide rail; the hand lifting motor is connected to the hand lifting screw rod, the hand lifting screw rod is connected to the hand upper and lower slider assembly, the hand upper and lower slider assembly is slidably connected to the hand lifting guide rail, and the hand upper and lower slider assembly is fixedly connected to the sample adding card strip hand; The carrying and pulling hand device includes a carrying card bar pull hand, a carrying card bar pull hand motor, a carrying card bar pull hand screw, a carrying card bar pull hand guide rail and a carrying card bar pull hand horizontal slider assembly. The carrying card bar pull hand motor is connected to the carrying card bar pull hand screw, the carrying card bar pull hand screw is slidably connected to the carrying card bar pull hand horizontal slider assembly, and the carrying card bar pull hand horizontal slider assembly is slidably connected to the carrying card bar pull hand guide rail; the carrying card bar pull hand is fixedly connected to the carrying card bar pull hand horizontal slider assembly.

15. The automatic sample loading machine for pipeline detection according to claim 14, characterized in that: The card strip fixing platform is provided with a card strip fixing spring piece for fixing the reagent card strip on the card strip fixing platform.

16. The automatic sample loading machine for pipeline detection according to claim 14, characterized in that: The translation transmission mechanism of the carrier device and the horizontal transmission mechanism of the sample adding and pulling hand device have the same structure, both of which include a driving wheel 1, a driven wheel 1 and a synchronous belt 1, and the synchronous belt is connected to the outer sides of the driving wheel 1 and the driven wheel 1.

17. A method for automatic sample loading using the automatic sample loading machine according to any one of claims 13 to 16, characterized in that: The specific steps include: (1) Turn on the power and wait for the automatic sampler to be initialized and ready; (2) After the import test items are completed; When in normal mode, place a sample rack with a sample cup and reagent card strips of the corresponding test items on the sample platform, click Start Test, and push the sample rack on the sample platform into the sample rack loading platform using the sample pusher; When the emergency mode is needed, press the emergency button to start the emergency mode, place the sample rack with the sample cup and the reagent card strips of the corresponding test items on the sample rack stage, and click to start the test; If you need to switch to emergency mode in normal mode, press the emergency button. The injection platform will stop injecting samples. If there is an unprocessed sample rack on the sample rack stage, wait until the sample rack is processed and the reagent card enters the carrier. Then put the sample cup with the emergency sample, the diluent cup and the reagent card of the corresponding test item into the sample rack stage and click to start the test. (3) The sample rack stage is driven by the stage motion component to move to the sample scanning position. The barcode of the sample cup is scanned by the sample scanner, and an information adding box pops up. After entering the information, click Submit. (4) The reagent card barcode scanner scans the barcode of the reagent card and uploads it to the host computer; (5) After the host computer confirms that the reagent card strip is correct, the sample adding device dilutes and mixes the sample in the sample cup in the sample rack through puncture sampling, and then adds the diluted and mixed sample to the reagent card strip; The sample adding device separates the reagent card strip and the sample rack; (6) The sample rack is lowered and pushed to the disposal platform, and the reagent card strip is transported by the transport device to the sample inlet of the detection instrument.

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