A high-throughput magnetic stand suitable for multiple calibers

By designing a multi-diameter suitable high-throughput magnetic rack, the existing magnetic racks have been solved, and the adaptation and efficient magnetic adsorption of centrifuge tubes of different specifications and shapes have been achieved, thus improving the improvement of the adaptation and efficient magnetic adsorption of centrifuge tubes. The flux operation and practicality of the magnetic shelf.

CN110540929BActive Publication Date: 2025-02-18BEIJING CHOSENMED MEDICAL INSTR CO LTD
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Patent Information

Application Number
CN201910422170.1
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2019-05-21
Publication Date
2025-02-18
Estimated Expiration
2039-05-21

AI Technical Summary

Technical Problem

The existing magnetic stands are not magnetically strong enough, have high working costs, and are not suitable for sufficient applicability. They cannot effectively adsorb small particle size and non-silicon hydroxyl beads, and cannot adapt to centrifuge tubes of different specifications and shapes.

Method used

A multi-diameter suitable high-throughput magnetic rack is designed, using multi-diameter suitable centrifugal tube grooves, super-strong neodymium iron boron magnets, removable and replaceable magnetic pillars and magnetic rack base, combining high-throughput magnetic devices and adjustable Magnetic pillars improve magnetic strength and applicability.

Benefits of technology

Achieve adaptation to different specifications and shapes of centrifuge tubes, improve the flux operation capability of the magnetic stand, enhance the adsorption capacity of smaller particle sizes and non-silicon hydroxyl beads, reduce work costs, and improve the magnetic stand practicality and adaptability.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses a high-throughput magnetic frame applicable to multiple calibers, comprising a magnetic frame main body, a centrifugal tube slot applicable to multiple calibers, a high-throughput magnetic device, a detachable and replaceable magnetic support and a magnetic frame base, wherein the top of the magnetic frame main body is fixedly connected with the centrifugal tube slot applicable to multiple calibers, the top inner side of the centrifugal tube slot applicable to multiple calibers is embedded with the high-throughput magnetic device, the front bottom of the magnetic frame main body is fixedly connected with a magnetic absorption storage groove, the front middle part of the magnetic frame main body is embedded with a magnetic absorption visual window, the magnetic absorption visual window well reflects the real-time performance of the magnetic frame, the magnetic absorption storage groove well reflects the convenience of the magnetic frame, the buffer spring bottom plate well improves the buffering performance of the magnetic frame, the centrifugal tube slot applicable to multiple calibers well improves the adaptability of the magnetic frame, the high-throughput magnetic device well improves the magnetic strength of the magnetic device, the magnetic frame is suitable for use in biological devices, and has broad development prospects in the future.
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Description

Technical Field

[0001] The invention belongs to the technical field of biological devices, and in particular relates to a high-throughput magnetic frame applicable to multiple calibers. Background Art

[0002] In the field of molecular biology, nucleic acid extraction and purification of samples are often required, and then the target fragments are amplified and tested. With the rapid development of biotechnology and medical diagnostic technology, the demand for high-throughput extraction and purification of samples has become increasingly obvious. Traditional sample processing, extraction, and purification methods can no longer meet the needs of daily work, especially clinical diagnosis. Currently, there are more and more workstations based on the principles of pipetting, magnetic beads, and membrane columns in clinical testing departments. The cost of large-scale sample processing workstations is about one million yuan or more, which is very expensive. Magnetic racks can be purchased for only a few hundred yuan, do not take up space, and are easy to use.

[0003] The magnetic rods of the existing magnetic racks are easy to break and cannot be replaced, which increases the working cost. The magnetic strength of the existing magnetic racks is not enough, and the adsorption capacity for non-silicon hydroxyl magnetic beads such as smaller particle sizes, carboxyl magnetic beads, polystyrene magnetic beads is weak, and more time is required to wait for magnetic absorption. In addition, the specifications and shapes of existing centrifuge tubes are different. The same magnetic rack cannot be used to make centrifuge tubes of multiple specifications for extraction, and the applicability is insufficient.

[0004] Therefore, how to design a high-throughput magnetic rack suitable for multiple calibers has become a problem to be solved at present. Summary of the invention

[0005] The purpose of the present invention is to provide a high-flux magnetic frame applicable to multiple calibers in order to solve the problems of insufficient magnetic strength, high working cost and insufficient applicability of a high-flux magnetic frame applicable to multiple calibers.

[0006] The technical solution adopted by the present invention is as follows: a high-throughput magnetic frame applicable to multiple calibers, comprising a magnetic frame body, a centrifugal tube slot applicable to multiple calibers, a high-throughput magnetic device, a detachable and replaceable magnetic support and a magnetic frame base, wherein the top of the magnetic frame body is fixedly connected with the centrifugal tube slot applicable to multiple calibers, the top inner side of the centrifugal tube slot applicable to multiple calibers is embedded with a high-throughput magnetic device, the top two sides of the centrifugal tube slot applicable to multiple calibers are movably connected with detachable and replaceable magnetic supports, and the bottom end of the magnetic frame body is fixedly connected with the magnetic frame base;

[0007] The top of the centrifuge tube tank applicable to multiple calibers is movably connected with an adjustable centrifuge tube tank, the inner side of the adjustable centrifuge tube tank is movably connected with an adjusting roller axle, the inner side of the adjusting roller axle is movably connected with a retractable movable rod, the other side of the inner side of the centrifuge tube tank applicable to multiple calibers is fixedly connected with a long tube embedding groove, one side of the inner bottom of the centrifuge tube tank applicable to multiple calibers is penetrated with a centrifuge tube batch embedding groove, and the other side of the inner side of the centrifuge tube tank applicable to multiple calibers is penetrated with a rectangular tube embedding groove;

[0008] The top of the high-flux magnetic device is embedded with a centrifugal tube to be attracted, one side of the high-flux magnetic device is movably connected with a left adsorption magnetic column, the other side of the high-flux magnetic device is movably connected with a right adsorption magnetic column, the top of the right adsorption magnetic column is movably connected with a spacing adjustment wheel, the bottom of the high-flux magnetic device is movably connected with a super-strong NdFeB magnet, and the bottom of the super-strong NdFeB magnet is movably connected with a lifting magnetic adjustment column;

[0009] The top two sides of the detachable and replaceable magnetic support are movably connected with detachable frame column caps, the inner side of the detachable frame column caps is penetrated by a disassembly fixing pin, one side of the inner part of the detachable and replaceable magnetic support is embedded with a left hollow magnet slot, the other side of the inner part of the detachable and replaceable magnetic support is embedded with a right hollow magnet slot, the inner side of the left hollow magnet slot is movably connected with a double spring anti-breakage limit plate, and the middle part of the inner part of the left hollow magnet slot is fixedly connected with a replaceable embedded magnet block.

[0010] Preferably, a magnetic absorption visual window is embedded and connected to the front middle part of the magnetic frame body.

[0011] Preferably, a magnetic absorption storage groove is fixedly connected to the front bottom of the magnetic frame body.

[0012] Preferably, the inner bottom of the detachable and replaceable magnetic support is electrically connected to an internal lighting lamp bead.

[0013] Preferably, a stable friction chassis is fixedly connected to both sides of the inner part of the magnetic frame base.

[0014] Preferably, a buffer spring bottom plate is movably connected to the inner middle portion of the magnetic frame base.

[0015] Preferably, the centrifuge tube slot applicable to multiple calibers is composed of an adjustable centrifuge tube slot at the top, an adjusting roller axle on the inner side of the adjustable centrifuge tube slot, an expansion and contraction movable rod on the inner side of the adjusting roller axle, a long tube embedding slot on the other side of the interior, a centrifuge tube batch embedding slot on one side of the bottom of the interior, and a rectangular tube embedding slot on the other side of the interior. At the same time, the adjustable centrifuge tube slot, the adjusting roller axle, the expansion and contraction movable rod, the long tube embedding slot, the centrifuge tube batch embedding slot and the rectangular tube embedding slot are arranged in sequence from left to right.

[0016] Preferably, the high-flux magnetic device is composed of a centrifugal tube to be attracted at the top of the interior, a left adsorption magnetic column on one side of the interior, a right adsorption magnetic column on the other side of the interior, a spacing adjustment wheel at the top of the right adsorption magnetic column, an ultra-strong NdFeB magnet at the bottom of the interior, and a lifting magnetic adjustment column at the bottom of the ultra-strong NdFeB magnet. At the same time, the centrifugal tube to be attracted, the left adsorption magnetic column, the right adsorption magnetic column, the spacing adjustment wheel, the ultra-strong NdFeB magnet and the lifting magnetic adjustment column are arranged in sequence from top to bottom.

[0017] Preferably, the removable and replaceable magnetic support is composed of removable column caps on both sides of the top, disassembly and fixing pins on the inner side of the removable column cap, a left hollow magnet slot on one side of the interior, a right hollow magnet slot on the other side of the interior, a double spring anti-breaking limit plate on the inner side of the left hollow magnet slot and a replaceable embedded magnet block in the middle part of the left hollow magnet slot. At the same time, the removable column cap, disassembly and fixing pins, the left hollow magnet slot, the right hollow magnet slot, the double spring anti-breaking limit plate and the replaceable embedded magnet block are arranged in sequence from top to bottom.

[0018] In summary, due to the adoption of the above technical solution, the beneficial effects of the present invention are:

[0019] 1. In the present invention, by providing a centrifuge tube slot applicable to multiple calibers, a long tube embedding slot, a centrifuge tube batch embedding slot and a rectangular tube embedding slot are provided at the same time, so that different centrifuge tubes with longer lengths, larger quantities and rectangular shapes can be adapted respectively, thereby achieving the effect of flux operation and greatly improving the adaptability of the magnetic frame.

[0020] 2. In the present invention, the super strong NdFeB magnet can effectively adsorb non-silicon hydroxyl magnetic beads such as smaller particle size, carboxyl magnetic beads, polystyrene magnetic beads, etc. At the same time, the staff can adjust the horizontal position and spacing of the magnet through the spacing adjustment wheel and the lifting magnetic adjustment column according to actual needs, thereby greatly improving the magnetic strength of the magnetic device.

[0021] 3. In the present invention, by setting a detachable and replaceable magnetic support, the double spring anti-breakage limit plate set at the same time can play a good protective and limiting role for the embedded replaceable embedded magnet block, and the double spring anti-breakage limit plate can replace the replaceable embedded magnet block according to actual needs, which well reflects the practicality of the magnetic frame. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a schematic diagram of the structure of the present invention;

[0023] Figure 2 It is a schematic diagram of the cross-sectional structure of a centrifuge tube tank applicable to multiple calibers of the present invention;

[0024] Figure 3 It is a schematic diagram of the structure of the high-flux magnetic device of the present invention;

[0025] Figure 4 A schematic diagram of the cross-sectional structure of a detachable and replaceable magnetic support according to the present invention;

[0026] Figure 5 It is a schematic diagram of the cross-sectional structure of the magnetic frame base of the present invention.

[0027] Markings in the figure: 1. Magnetic frame body, 2. Centrifuge tube slot for multiple calibers, 201. Adjustable slot for centrifuge tubes, 202. Adjustment roller axle, 203. Retractable movable rod, 204. Long tube embedding slot, 205. Centrifuge tube batch embedding slot, 206. Rectangular tube embedding slot, 3. High-throughput magnetic device, 301. Centrifuge tube to be magnetically attracted, 302. Left adsorption magnetic column, 303. Right adsorption magnetic column, 304. Spacing adjustment wheel, 305. Super strong NdFeB Magnet, 306, lifting magnetic adjustment column, 4, removable and replaceable magnetic support, 401, removable column cap, 402, disassembly and assembly fixing pin, 403, left hollow magnet slot, 404, right hollow magnet slot, 405, double spring anti-break limit plate, 406, replaceable embedded magnet block, 407, internal lighting beads, 5, magnetic frame base, 501, stable friction chassis, 502, buffer spring bottom plate, 6, magnetic absorption viewing window, 7, magnetic absorption storage slot. DETAILED DESCRIPTION

[0028] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0029] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific position, be constructed and operated in a specific position, and therefore cannot be understood as limiting the present invention; the terms "first", "second", and "third" are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance; in addition, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be a connection between the two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0030] See also Figure 1-5 , the present invention provides a technical solution:

[0031] Example 1

[0032] A high-throughput magnetic rack applicable to multiple calibers comprises a magnetic rack body 1, a centrifugal tube slot applicable to multiple calibers 2, a high-throughput magnetic device 3, a detachable and replaceable magnetic support 4 and a magnetic rack base 5, wherein the top of the magnetic rack body 1 is fixedly connected with the centrifugal tube slot applicable to multiple calibers 2, the top inner side of the centrifugal tube slot applicable to multiple calibers 2 is embedded with the high-throughput magnetic device 3, the top two sides of the centrifugal tube slot applicable to multiple calibers 2 are movably connected with the detachable and replaceable magnetic support 4, and the bottom end of the magnetic rack body 1 is fixedly connected with the magnetic rack base 5;

[0033] The top of the centrifuge tube tank 2 applicable to multiple calibers is movably connected with an adjustable centrifuge tube tank 201, the inner side of the adjustable centrifuge tube tank 201 is movably connected with an adjusting roller axle 202, the inner side of the adjusting roller axle 202 is movably connected with a telescopic movable rod 203, the other side of the inner side of the centrifuge tube tank 2 applicable to multiple calibers is fixedly connected with a long tube embedding groove 204, one side of the inner bottom of the centrifuge tube tank 2 applicable to multiple calibers is penetrated with a centrifuge tube batch embedding groove 205, and the other side of the inner side of the centrifuge tube tank 2 applicable to multiple calibers is penetrated with a rectangular tube embedding groove 206;

[0034] A centrifugal tube 301 to be attracted is embedded in the top of the high-flux magnetic device 3, a left adsorption magnetic column 302 is movably connected to one side of the high-flux magnetic device 3, a right adsorption magnetic column 303 is movably connected to the other side of the high-flux magnetic device 3, a spacing adjustment wheel 304 is movably connected to the top of the right adsorption magnetic column 303, a super-strong NdFeB magnet 305 is movably connected to the bottom of the high-flux magnetic device 3, and a lifting magnetic adjustment column 306 is movably connected to the bottom of the super-strong NdFeB magnet 305;

[0035] The top two sides of the detachable and replaceable magnetic support 4 are movably connected with detachable frame column caps 401, the inner side of the detachable frame column cap 401 is penetrated by a disassembly fixing pin 402, one side of the interior of the detachable and replaceable magnetic support 4 is embedded with a left hollow magnet groove 403, the other side of the interior of the detachable and replaceable magnetic support 4 is embedded with a right hollow magnet groove 404, the inner side of the left hollow magnet groove 403 is movably connected with a double spring anti-breakage limit plate 405, and the middle part of the interior of the left hollow magnet groove 403 is fixedly connected with a replaceable embedded magnet block 406.

[0036] Example 2

[0037] Preferably, a magnetic absorption visual window 6 is embedded and connected to the front middle part of the magnetic frame body 1. When performing the magnetic absorption operation, in order to ensure the magnetic absorption effect, the magnetic frames mostly adopt a closed structure. The existing magnetic frames cannot observe the internal magnetic absorption conditions in real time under the closed structure, and the real-time performance is insufficient. By setting the magnetic absorption visual window 6, the magnetic absorption visual window 6 is a transparent and visible hard glass material, and the staff can view the internal magnetic absorption conditions in real time through the magnetic absorption visual window 6, thereby well reflecting the real-time performance of the magnetic frame.

[0038] Example 3

[0039] Preferably, a magnetic storage slot 7 is fixedly connected to the front bottom of the magnetic frame body 1. When the staff conducts real-time monitoring, they need to carry some tool parts, which increases the trouble of the staff. By setting the magnetic storage slot 7, the magnetic storage slot 7 is a built-in storage slot, and the staff can place the relevant magnetic tool parts into the magnetic storage slot 7, which is convenient for taking at any time when used, thereby well reflecting the convenience of the magnetic frame.

[0040] Example 4

[0041] Preferably, the inner bottom of the detachable and replaceable magnetic support 4 is electrically connected with an internal lighting lamp bead 407. When the magnetic absorption work is performed at night or in a night environment with low brightness, the staff cannot observe and monitor the details inside the magnetic frame well, and the practicality is insufficient. By setting the internal lighting lamp bead 407, the internal lighting lamp bead 407 is set inside the magnetic frame, which can well illuminate and cover the internal structure of the magnetic frame, thereby playing a good role in supplementary lighting, and well reflects the practicality of the magnetic frame.

[0042] Example 5

[0043] Preferably, a stable friction chassis 501 is fixedly connected to both sides of the interior of the magnetic frame base 5. Most of the existing magnetic frame bottom plates are relatively smooth, and are prone to slipping during magnetic absorption operations, which affects the operation of the staff. By setting a stable friction chassis 501, the bottom of the stable friction chassis 501 is provided with multiple concave and convex anti-sliding blocks, which can greatly enhance the grip of the base, thereby preventing the magnetic frame from slipping, and well reflects the anti-slip property of the magnetic frame.

[0044] Example 6

[0045] Preferably, a buffer spring bottom plate 502 is movably connected to the inner middle part of the magnetic frame base 5. When the magnetic frame is operated, manual pressing and other operations will produce a certain impact on the device body, causing certain damage to the device body. By setting the buffer spring bottom plate 502, the buffer spring bottom plate 502 has a shock-absorbing spring seat with multiple springs, which can generate a good buffering force when the staff touches it, thereby greatly improving the buffering property of the magnetic frame.

[0046] Example 7

[0047] Preferably, the centrifuge tube slot 2 applicable to multiple calibers is composed of an adjustable centrifuge tube slot 201 at the top, an adjusting roller axle 202 inside the adjustable centrifuge tube slot 201, an expansion and contraction movable rod 203 inside the adjusting roller axle 202, a long tube embedding slot 204 on the other side of the interior, a centrifuge tube batch embedding slot 205 on one side of the bottom of the interior and a rectangular tube embedding slot 206 on the other side of the interior. The centrifuge tube batch embedding slot 205 and the rectangular tube embedding slot 206 on the other side of the interior are combined together, and the centrifuge tube adjustable slot 201, the adjusting roller axle 202, the expansion and contraction movable rod 203, the long tube embedding slot 204, the centrifuge tube batch embedding slot 205 and the rectangular tube embedding slot 206 are arranged from left to right in sequence. The sizes and shapes of the centrifuge tubes are different. The existing device cannot use the same magnetic frame to make centrifuge tubes of multiple specifications for extraction and use, and the applicability is insufficient. By setting a centrifuge tube slot 2 applicable to multiple calibers, the centrifuge tube adjustable slot 201 is set in the centrifuge tube slot 2 applicable to multiple calibers. The staff can drive the expansion and contraction movable rod 203 to expand or shrink by adjusting the roller shaft 202, thereby adjusting the caliber of the centrifuge tube. At the same time, a long tube embedding slot 204, a centrifuge tube batch embedding slot 205 and a rectangular tube embedding slot 206 are set, which can respectively adapt to different centrifuge tubes with longer lengths, larger quantities and rectangular shapes, thereby achieving the effect of flux operation and greatly improving the adaptability of the magnetic frame.

[0048] Example 8

[0049] Preferably, the high-throughput magnetic device 3 is composed of a centrifuge tube 301 to be attracted at the top of the interior, a left adsorption magnetic column 302 on one side of the interior, a right adsorption magnetic column 303 on the other side of the interior, a spacing adjustment wheel 304 at the top of the right adsorption magnetic column 303, a super strong NdFeB magnet 305 at the bottom of the interior, and a lifting magnetic force adjustment column 306 at the bottom of the super strong NdFeB magnet 305. At the same time, the centrifuge tube 301 to be attracted, the left adsorption magnetic column 302, the right adsorption magnetic column 303, the spacing adjustment wheel 304, the super strong NdFeB magnet 305 and the lifting magnetic force adjustment column 306 are arranged in sequence from top to bottom. The magnetic strength of the existing magnetic frame is not enough. For smaller particle sizes, carboxyl magnetic beads, and polymers, The adsorption capacity of non-silicon hydroxyl magnetic beads such as styrene magnetic beads is weak, and more time is needed to wait for magnetic attraction. By setting up a high-flux magnetic device 3, a left adsorption magnetic column 302 and a right adsorption magnetic column 303 are arranged inside the high-flux magnetic device 3, which can strongly adsorb conventional magnetic beads. At the same time, an ultra-strong neodymium iron boron magnet 305 is arranged. The ultra-strong neodymium iron boron magnet 305 can effectively adsorb non-silicon hydroxyl magnetic beads such as smaller particle sizes, carboxyl magnetic beads, polystyrene magnetic beads, etc. At the same time, the staff can adjust the horizontal position and spacing of the magnets through the spacing adjustment wheel 304 and the lifting magnetic adjustment column 306 according to actual needs, thereby greatly improving the magnetic strength of the magnetic device.

[0050] Example 9

[0051] Preferably, the detachable and replaceable magnetic support 4 is composed of detachable column caps 401 on both sides of the top, detachable fixing pins 402 on the inner side of the detachable column caps 401, a left hollow magnet slot 403 on one side of the interior, a right hollow magnet slot 404 on the other side of the interior, a double spring anti-breaking limit plate 405 on the inner side of the left hollow magnet slot 403, and a replaceable embedded magnet block 406 in the middle part of the left hollow magnet slot 403. At the same time, the detachable column cap 401, the detachable fixing pin 402, the left hollow magnet slot 403, the right hollow magnet slot 404, the double spring anti-breaking limit plate 405 and the replaceable embedded magnet block 406 are arranged in sequence from top to bottom, and the magnetic bars of the existing magnetic frame are easy to be removed. The detachable and replaceable magnetic support 4 is provided with a left hollow magnet slot 403 and a right hollow magnet slot 404. When installation is required, the disassembly and assembly fixing pin 402 is inserted into the detachable frame column cap 401 fixed inside the left hollow magnet slot 403. When disassembling, the disassembly and assembly fixing pin 402 can be pulled out, which is convenient and quick. At the same time, the double spring anti-breaking limit plate 405 can well protect and limit the embedded replaceable embedded magnet block 406, and the double spring anti-breaking limit plate 405 can replace the replaceable embedded magnet block 406 according to actual needs, which well reflects the practicality of the magnetic frame.

[0052] Example 10

[0053] Application: First, by setting the internal lighting lamp beads 407, the internal lighting lamp beads 407 are set inside the magnetic frame, which can well illuminate and cover the internal structure of the magnetic frame, thereby playing a good role in supplementary lighting and well reflecting the practicality of the magnetic frame.

[0054] Then, by setting the buffer spring bottom plate 502, the buffer spring bottom plate 502 has a plurality of spring shock-absorbing spring seats, which can well generate a buffering force when the staff touches it, thereby well improving the buffering performance of the magnetic frame.

[0055] Next, by setting up a centrifuge tube slot 2 applicable to multiple calibers, an adjustable centrifuge tube slot 201 is set in the centrifuge tube slot 2. The staff can drive the expansion and contraction movable rod 203 to expand or shrink by adjusting the roller shaft 202, thereby adjusting the caliber of the centrifuge tube. At the same time, a long tube embedding slot 204, a centrifuge tube batch embedding slot 205 and a rectangular tube embedding slot 206 are provided, which can respectively adapt to different centrifuge tubes with longer lengths, larger quantities and rectangular shapes, thereby achieving the effect of flux operation and greatly improving the adaptability of the magnetic frame.

[0056] Next, a centrifuge tube slot 2 suitable for multiple calibers is set, and a high-flux magnetic device 3 is set. The high-flux magnetic device 3 is provided with a left adsorption magnetic column 302 and a right adsorption magnetic column 303 inside, which can strongly adsorb conventional magnetic beads. At the same time, an ultra-strong neodymium iron boron magnet 305 is provided. The ultra-strong neodymium iron boron magnet 305 can effectively adsorb non-silicon hydroxyl magnetic beads such as smaller particle sizes, carboxyl magnetic beads, polystyrene magnetic beads, etc. At the same time, the staff can adjust the horizontal position and spacing of the magnets through the spacing adjustment wheel 304 and the lifting magnetic adjustment column 306 according to actual needs, thereby greatly improving the magnetic strength of the magnetic device.

[0057] Finally, by setting a detachable and replaceable magnetic support 4, a left hollow magnet slot 403 and a right hollow magnet slot 404 are set in the detachable and replaceable magnetic support 4. When installation is required, the disassembly and assembly fixing pin 402 can be inserted into the detachable frame column cap 401 fixed inside the left hollow magnet slot 403. When disassembling, the disassembly and assembly fixing pin 402 can be pulled out. It is convenient and quick. At the same time, the double spring anti-breaking limit plate 405 can well protect and limit the embedded replaceable embedded magnet block 406, and the double spring anti-breaking limit plate 405 can replace the replaceable embedded magnet block 406 according to actual needs, which well reflects the practicality of the magnetic frame. This is the working principle of this multi-caliber applicable high-throughput magnetic frame.

[0058] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A high-throughput magnetic rack applicable to multiple calibers, comprising a magnetic rack body (1), a centrifuge tube tank applicable to multiple calibers (2), a high-throughput magnetic device (3), a detachable and replaceable magnetic support (4) and a magnetic rack base (5), characterized in that: The top of the magnetic frame body (1) is fixedly connected to a centrifuge tube slot (2) applicable to multiple calibers, a high-flux magnetic device (3) is embedded and connected to the inner side of the top of the centrifuge tube slot (2) applicable to multiple calibers, and detachable and replaceable magnetic pillars (4) are movably connected to both sides of the top of the centrifuge tube slot (2) applicable to multiple calibers, and the bottom of the magnetic frame body (1) is fixedly connected to a magnetic frame base (5); The top of the centrifuge tube slot (2) applicable to multiple calibers is movably connected to an adjustable centrifuge tube slot (201), the inner side of the adjustable centrifuge tube slot (201) is movably connected to an adjusting roller axle (202), the inner side of the adjusting roller axle (202) is movably connected to a telescopic movable rod (203), the other side of the inner side of the centrifuge tube slot (2) applicable to multiple calibers is fixedly connected to a long tube embedding slot (204), one side of the inner bottom of the centrifuge tube slot (2) applicable to multiple calibers is penetrated by a centrifuge tube batch embedding slot (205), and the other side of the inner side of the centrifuge tube slot (2) applicable to multiple calibers is penetrated by a rectangular tube embedding slot (206); The top of the high-flux magnetic device (3) is embedded with a centrifuge tube (301) to be attracted by magnetism, one side of the high-flux magnetic device (3) is movably connected to a left adsorption magnetic column (302), the other side of the high-flux magnetic device (3) is movably connected to a right adsorption magnetic column (303), the top of the right adsorption magnetic column (303) is movably connected to a spacing adjustment wheel (304), the bottom of the high-flux magnetic device (3) is movably connected to an ultra-strong neodymium iron boron magnet (305), and the bottom of the ultra-strong neodymium iron boron magnet (305) is movably connected to a lifting magnetic adjustment column (306); the detachable and replaceable magnetic device (3) is provided with a plurality of magnetic poles (304) and a plurality of magnetic poles (306) for adjusting the magnetic force. The top two sides of the pillar (4) are movably connected with detachable column caps (401), the inner side of the detachable column cap (401) is penetrated with a disassembly fixing pin (402), the inner side of the detachable magnetic pillar (4) is embedded with a left hollow magnet groove (403), the other side of the detachable magnetic pillar (4) is embedded with a right hollow magnet groove (404), the inner side of the left hollow magnet groove (403) is movably connected with a double spring anti-breaking limit plate (405), and the middle part of the left hollow magnet groove (403) is fixedly connected with a replaceable embedded magnet block (406); The inner bottom of the detachable and replaceable magnetic support (4) is electrically connected to an internal lighting lamp bead (407); the inner middle part of the magnetic frame base (5) is movably connected to a buffer spring bottom plate (502).

2. A high-throughput magnetic stand suitable for multiple apertures as claimed in claim 1, characterized in that: A magnetic absorption visual window (6) is embedded and connected in the middle of the front of the magnetic frame body (1); a magnetic absorption storage groove (7) is fixedly connected to the front bottom of the magnetic frame body (1); and a stable friction chassis (501) is fixedly connected to the inner sides of the magnetic frame base (5).

3. An application of the multi-aperture applicable high-throughput magnetic stand as claimed in claim 1, characterized in that: Firstly, by providing an internal lighting lamp bead (407), the internal lighting lamp bead (407) is provided inside the magnetic frame, so that the internal structure of the magnetic frame can be well illuminated and covered, thereby playing a good role in supplementary lighting, and well reflecting the practicality of the magnetic frame; then, by providing a buffer spring bottom plate (502), the buffer spring bottom plate (502) has a plurality of spring shock-absorbing spring seats, which can well generate a buffering force when the staff touches it, thereby well improving the buffering property of the magnetic frame; then, by providing a centrifuge tube slot (2) applicable to multiple calibers, the internal structure of the centrifuge tube slot (2) applicable to multiple calibers can be well illuminated and covered, thereby playing a good role in supplementary lighting, and well reflecting the practicality of the magnetic frame; then, by providing a buffer spring bottom plate (502), the buffer spring bottom plate (502) has a plurality of spring shock-absorbing spring seats, which can well generate a buffering force when the staff touches it, thereby well improving the buffering property of the magnetic frame; An adjustable centrifuge tube slot (201) is provided, and a staff member can drive the expansion and contraction movable rod (203) to expand or contract by adjusting the roller shaft (202), thereby adjusting the caliber of the centrifuge tube. At the same time, a long tube embedding slot (204), a centrifuge tube batch embedding slot (205) and a rectangular tube embedding slot (206) are provided, which can respectively adapt to different centrifuge tubes with longer lengths, larger quantities and rectangular shapes, thereby achieving the effect of flux operation and improving the adaptability of the magnetic frame. Next, by providing a centrifuge tube slot (2) suitable for multiple calibers, by providing a high-throughput magnetic The high-flux magnetic device (3) is provided with a left adsorption magnetic column (302) and a right adsorption magnetic column (303) inside, which can strongly adsorb conventional magnetic beads. At the same time, an ultra-strong neodymium iron boron magnet (305) is provided. The ultra-strong neodymium iron boron magnet (305) can effectively adsorb non-silicon hydroxyl magnetic beads with smaller particle sizes. At the same time, the staff can adjust the horizontal position and spacing of the magnets through the spacing adjustment wheel (304) and the lifting magnetic force adjustment column (306) according to actual needs, thereby greatly improving the magnetic strength of the magnetic device; finally, by providing a detachable and replaceable magnetic support (4), the detachable A left hollow magnet slot (403) and a right hollow magnet slot (404) are arranged inside the replaceable magnetic support (4). When installation is required, the disassembly fixing pin (402) is inserted into the detachable frame column cap (401) fixed inside the left hollow magnet slot (403). When disassembling, the disassembly fixing pin (402) can be pulled out, which is convenient and quick. At the same time, the double spring anti-breaking limit plate (405) can well protect and limit the embedded replaceable embedded magnet block (406), and the double spring anti-breaking limit plate (405) can replace the replaceable embedded magnet block (406) according to actual needs.

Citation Information

Patent Citations

  • Multi-caliber applicable high-flux magnetic frame

    CN210215329U