Chemiluminescent immunoassay analyzer and its detection dark box

Abstract

The present invention discloses a chemiluminescent immunoassay instrument and a detection dark box thereof. The chemiluminescent immunoassay detection dark box comprises a first shell, a second shell and a shell cover. The upper end of the first shell is open, and the side of the first shell is provided with a first connecting hole corresponding to a photon counter; the second shell is movably inserted at the upper end opening of the first shell, and the upper end of the second shell is provided with a cup placement hole for a reaction cup to be placed, and the side of the second shell is provided with a second connecting hole connected to the lower end of the cup placement hole, the second shell can move up and down relative to the first shell, the first connecting hole can be connected with the second connecting hole, the photon counter can detect the luminescence of the reaction cup in the second connecting hole through the first connecting hole, and the second shell can cover the first connecting hole; the lower end of the shell cover is provided with an avoidance hole for the reaction cup to extend into, and the shell cover can cover the upper end of the second shell. The present invention has a good detection reading effect and a high detection accuracy.

Description

Technical Field

[0001] This invention relates to the field of medical testing, and in particular to a chemiluminescence immunoassay analyzer and its detection dark chamber. Background Technology

[0002] Chemiluminescence immunoassay is a detection method that utilizes the specific reaction between antigens and antibodies. It amplifies and displays the detection signal using isotopes, enzymes, and chemiluminescent substances. In the experiment, the antigen or antibody is conjugated with an enzyme to form an enzyme-labeled antigen or antibody. This enzyme-labeled antigen or antibody retains both its immunogenicity and enzyme activity. After washing, a luminescent solution is added, and the reaction vessel is placed in a dark chamber for detection. The amount of light emitted by the substances in the reaction vessel within the dark chamber is measured, thus achieving luminescent immunoassay of the detection solution. Existing chemiluminescence immunoassay analyzers primarily use photometric elements such as photon counters to detect the amount of light emitted by the detection solution in the dark chamber. However, in traditional methods, after the photometric element is installed, its detection end is constantly connected to the inside of the dark chamber. This means the detection end of the photometric element is easily exposed, especially when the dark chamber opening is open, allowing natural light to enter and expose the detection end of the photometric element. This can damage the photometric element, reduce its lifespan, and affect the detection results, resulting in lower detection accuracy. Summary of the Invention

[0003] This invention aims to at least solve one of the technical problems existing in the prior art. To this end, this invention proposes a chemiluminescence immunoassay detection dark chamber, which has good detection reading effect and high detection accuracy.

[0004] The present invention also proposes a chemiluminescence immunoassay analyzer having the above-mentioned chemiluminescence immunoassay detection dark chamber.

[0005] According to a first aspect embodiment of the present invention, a chemiluminescence immunoassay detection dark chamber includes a first housing, a second housing, and a housing cover. The first housing has an opening at its upper end and a first connection hole corresponding to a photon counter is provided on its side. The second housing is movably inserted into the opening at the upper end of the first housing. The upper end of the second housing has a cup placement hole for inserting a reaction cup. The side of the second housing has a second connection hole communicating with the lower end of the cup placement hole. The second housing can move up and down relative to the first housing. The first connection hole can communicate with the second connection hole. The photon counter can detect the luminescence of the reaction cup in the second connection hole through the first connection hole. The second housing can shield the first connection hole. The lower end of the housing cover has a clearance hole for the reaction cup to extend into. The housing cover can shield the upper end of the second housing.

[0006] The chemiluminescence immunoassay dark chamber according to the embodiments of the present invention has at least the following beneficial effects: By setting a double-shell structure with a first shell and a second shell, and respectively providing a first connection hole and a second connection hole, during luminescence analysis detection, the photon counter is sealed and connected at the first connection hole, and the shell cover plate covers and shields the second shell, forming a dark chamber between the second shell and the shell cover plate. The second shell moves downward relative to the first shell, so that the first connection hole and the second connection hole are connected, facilitating the photon counter to detect the luminescence of the reaction cup in the second connection hole through the first connection hole. After the luminescence analysis detection is completed, the second shell moves upward relative to the first shell, so that the first connection hole and the second connection hole are completely offset, and the second shell shields the first connection hole, which can prevent the detection end of the photon counter from being exposed, thereby avoiding affecting the detection reading effect of the photon counter. At the same time, the detection end of the photon counter is always in a dark environment, enabling the present invention to have high detection accuracy.

[0007] According to some embodiments of the present invention, a guide structure is provided between the first housing and the second housing. By providing a guide structure to guide the relative movement between the second housing and the first housing, it is possible to avoid offset or relative rotation between the two housings, thereby improving the stability and reliability of their movement.

[0008] According to some embodiments of the present invention, the second housing is provided with a guide groove on its side, and the first housing is threadedly connected to a guide member that can cooperate with the guide groove. By providing the guide groove and guide member, the relative movement between the second housing and the first housing is guided. Furthermore, the guide member is threadedly connected to the first housing, making it detachable and replaceable. This allows for replacement when the guide member wears out due to prolonged use. Simultaneously, the threaded adjustment ensures that the guide member abuts against the guide groove, guaranteeing the stability of the connection between the first and second housings and preventing loosening. This prevents natural light from easily entering the first connection hole through loose gaps and affecting the photon counter's detection readings.

[0009] According to some embodiments of the present invention, a first stepped portion is provided on the inner side of the upper end of the first housing, and a second stepped portion is provided on the side of the second housing, which can abut against the first stepped portion. By providing the first stepped portion and the second stepped portion, when the second housing moves upward relative to the first housing, the abutment between the first stepped portion and the second stepped portion can limit the maximum stroke position of the second housing relative to the first housing, preventing the second housing from moving upward relative to the first housing and detaching from the first housing, thereby improving the stability and reliability of the connection between them.

[0010] According to some embodiments of the present invention, an elastic element is provided between the first housing and the second housing, the elastic element enabling the second housing to move upward and reset. By providing the elastic element, when the second housing moves downward relative to the first housing, the elastic element is compressed. After the detection is completed, the housing cover moves upward, and the second housing can be reset upward through the elastic element. Its structure is simple, facilitates the reset of the second housing, and reduces the volume of the present invention.

[0011] According to some embodiments of the present invention, the elastic element is a spring. The lower end of the first housing is provided with an upwardly protruding connecting boss, and the lower end of the second housing is provided with an upwardly recessed third connecting hole. One end of the elastic element is sleeved on the connecting boss and abuts against the bottom of the connecting boss, and the other end of the elastic element extends into the third connecting hole and abuts against the bottom of the third connecting hole. By setting the elastic element to a spring and having its two ends connected to the connecting boss and the third connecting hole respectively, the installation and connection of the elastic element can be facilitated, and the stability of its connection can be improved. At the same time, when the second housing moves downward relative to the first housing to compress the elastic element, the connecting boss can extend into the third connecting hole, improving the stability and reliability of the movement between the second housing and the first housing.

[0012] According to some embodiments of the present invention, the lower end of the housing cover plate is provided with a downwardly protruding annular protrusion, and the upper end of the first housing is provided with an annular connecting groove for the annular protrusion to be inserted. By providing the annular protrusion and the annular connecting groove, the housing cover plate covers the second housing and pushes it downward, and the annular protrusion is inserted into the annular connecting groove, so that the housing cover plate cooperates with the second housing and the first housing respectively to form a double-layer dark box structure, which has a better light-shielding effect. Moreover, when the annular protrusion is inserted into the annular connecting groove, the connection between the housing cover plate and the first housing forms a multi-layer structure, which can enhance the light-shielding and sealing effect, so that the photon counter has a better detection environment, and further improve the detection accuracy of the present invention.

[0013] According to some embodiments of the present invention, a sealing ring is provided within the annular connecting groove. By providing a sealing ring, the sealing effect when the annular protrusion and the annular connecting groove are connected can be further enhanced, thereby improving the sealing performance of the connection.

[0014] According to some embodiments of the present invention, the upper end of the housing cover is provided with a connecting seat, the lower end of the connecting seat is connected to the clearance hole, and a dropper assembly is detachably provided on the connecting seat. The dropper assembly can be connected to an external luminescent liquid delivery device, and the dropper assembly can add luminescent liquid to the reaction cup. By providing the connecting seat and the detachable dropper assembly, when the first connecting hole and the second connecting hole are fully connected, luminescent liquid can be added to the reaction cup through the dropper assembly, realizing the detection of the real-time luminescence in the reaction cup. This makes the present invention applicable to chemiluminescent immunoassay detection with different dropper modes, improving its applicability.

[0015] The chemiluminescence immunoassay analyzer according to a second aspect of the present invention includes a chemiluminescence immunoassay detection dark chamber according to the first aspect of the present invention described above.

[0016] The chemiluminescence immunoassay analyzer according to the embodiments of the present invention has at least the following beneficial effects: by using the above-mentioned chemiluminescence immunoassay detection dark chamber, the chemiluminescence immunoassay analyzer can achieve better luminescence detection effect, thus having higher detection accuracy and improving the reliability of its detection results. Attached Figure Description

[0017] The above and / or additional aspects and advantages of the present invention will become apparent and readily understood from the description of the embodiments taken in conjunction with the following drawings, in which:

[0018] Figure 1 This is a schematic diagram of the chemiluminescence immunoassay detection dark chamber in the detection state according to a first aspect embodiment of the present invention;

[0019] Figure 2 for Figure 1 One of the cross-sectional schematic diagrams of the dark chamber for chemiluminescence immunoassay.

[0020] Figure 3 for Figure 2 An enlarged schematic diagram of part A in the middle;

[0021] Figure 4 for Figure 1 Schematic diagram of the cross-section of the dark chamber for chemiluminescence immunoassay (CIA);

[0022] Figure 5 for Figure 1 A schematic diagram of the chemiluminescence immunoassay dark chamber in a non-detection state;

[0023] Figure 6 for Figure 5 One of the cross-sectional schematic diagrams of the dark chamber for chemiluminescence immunoassay.

[0024] Figure 7 for Figure 6 Enlarged schematic diagram of part B in the middle;

[0025] Figure 8 for Figure 5 Schematic diagram of the cross-section of the dark chamber for chemiluminescence immunoassay.

[0026] Figure label:

[0027] First housing 100, first connecting hole 110, photon counter 120, guide 130, first stepped portion 140, elastic element 150, connecting boss 160, annular connecting groove 170, sealing ring 171;

[0028] Second housing 200, cup placement hole 210, second connecting hole 220, guide groove 230, second stepped portion 240, third connecting hole 250, third stepped portion 260;

[0029] The housing cover plate 300, the clearance hole 310, the annular protrusion 320, the connecting seat 330, the dripping assembly 340, and the abutment part 350;

[0030] Reaction cup 1. Detailed Implementation

[0031] Embodiments of the present invention are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.

[0032] In the description of this invention, it should be understood that the orientation descriptions, such as up, down, etc., are based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limiting this invention.

[0033] If the terms "first" and "second" are used only to distinguish technical features, they should not be construed as indicating or implying relative importance, or implicitly indicating the number of technical features indicated, or implicitly indicating the order of the technical features indicated.

[0034] In the description of this invention, unless otherwise explicitly defined, terms such as "set up," "install," and "connect" should be interpreted broadly, and those skilled in the art can reasonably determine the specific meaning of the above terms in this invention in conjunction with the specific content of the technical solution.

[0035] Reference Figure 1 and Figure 2 A chemiluminescence immunoassay detection darkroom includes a first housing 100, a second housing 200, and a housing cover 300. The first housing 100 has an opening at its upper end, and a first connecting hole 110 corresponding to a photon counter 120 is provided on its side. The second housing 200 is movably inserted into the upper opening of the first housing 100. The upper end of the second housing 200 has a cup placement hole 210 for inserting a reaction cup 1, and a second connecting hole 220 communicating with the lower end of the cup placement hole 210 is provided on its side. The second housing 200 can move up and down relative to the first housing 100. The first connecting hole 110 can communicate with the second connecting hole 220. The photon counter 120... The luminescence of the reaction cup 1 in the second connection hole 220 can be detected through the first connection hole 110, and the second housing 200 can block the first connection hole 110; the lower end of the housing cover plate 300 is provided with a clearance hole 310 for the reaction cup 1 to extend into, and the housing cover plate 300 can block the upper end of the second housing 200.

[0036] By setting a double-layer shell structure with a first shell 100 and a second shell 200, and respectively providing a first connecting hole 110 and a second connecting hole 220, during luminescence analysis and detection, the photon counter 120 is sealed and connected at the first connecting hole 110, and the shell cover plate 300 covers and shields the second shell 200, forming a dark chamber between the second shell 200 and the shell cover plate 300. The second shell 200 moves downward relative to the first shell 100, so that the first connecting hole 110 and the second connecting hole 220 are connected, facilitating the photon counter 120 to pass through the first connecting hole 110 to the reaction cup 1 in the second connecting hole 220. The luminescence status is detected; after the luminescence analysis is completed, the second housing 200 moves upward relative to the first housing 100, so that the first connecting hole 110 and the second connecting hole 220 are completely misaligned. The second housing 200 blocks the first connecting hole 110, which can prevent the detection end of the photon counter 120 from being exposed, thereby avoiding affecting the detection reading effect of the photon counter 120. At the same time, the detection end of the photon counter 120 is always in a dark environment, so that the present invention can have high detection accuracy.

[0037] In this embodiment, as Figure 5 , Figure 6 and Figure 8As shown, when the invention is in a non-detection state, a photon counter 120 is connected to the first connection hole 110 of the first housing 100. The housing cover 300 is separated from the first housing 100 and the second housing 200. The first connection hole 110 and the second connection hole 220 are completely offset. The outer wall of the second housing 200 blocks the second connection hole 220 to prevent the detection end of the photon counter 120 from being affected by exposure. During detection, luminescent liquid is added to the pre-treated reaction cup 1 and placed into the cup placement hole 210. The housing cover 300 moves downward, first covering and shielding the second housing 200. The upper part forms a dark box structure. The housing cover plate 300 and the second housing 200 move downwards, gradually connecting the first connecting hole 110 and the second connecting hole 220. At this time, since the housing cover plate 300 has been placed on the upper part of the second housing 200, the detection end of the photon counter 120 can still be prevented from being affected by exposure after the first connecting hole 110 and the second connecting hole 220 are connected. The housing cover plate 300 continues to move downwards until it covers the first housing 100, such as... Figure 1 , Figure 2 As shown in Figure 4, the first connecting hole 110 and the second connecting hole 220 are in a fully connected state at this time, and the photon counter 120 detects the luminescence of the reaction cup 1 in the second connecting hole 220.

[0038] In practical applications, the housing cover plate 300 can be connected to the first housing 100 via a guide rail slider (not shown in the figure) or other structures. The downward movement of the housing cover plate 300 can be achieved by setting a driving device, manual placement or removal, or downward movement by its own weight. The movement of the second housing 200 can also be achieved by setting a driving device or other structures, and there are no restrictions here. The specific structures of the first housing 100 and the second housing 200 can also be set according to actual usage needs. The photon counter 120 can be installed at the first connecting hole 110 through other mounting structures, or it can be installed by cooperating with the first connecting hole 110. These will not be described in detail here, but will be explained in detail below.

[0039] In some embodiments, a guide structure is provided between the first housing 100 and the second housing 200. By providing a guide structure to guide the relative movement between the second housing 200 and the first housing 100, it is possible to prevent offset or relative rotation between the two housings, thereby improving the stability and reliability of their movement. In practical applications, the specific structural form of the guide structure can be various, such as a slide rail slider structure or a guide post wire hole structure, etc., which are not limited here. The specific form can be set according to the actual use needs, and will not be described in detail here, but will be explained in detail below.

[0040] In some embodiments, the second housing 200 has a guide groove 230 on its side, and the first housing 100 has a guide member 130 that can engage with the guide groove 230 via a threaded connection. The guide groove 230 and the guide member 130 guide the relative movement between the second housing 200 and the first housing 100. The threaded connection between the guide member 130 and the first housing 100 allows the guide member 130 to be detachable and replaceable, enabling replacement when it wears out after prolonged use. Furthermore, the threaded adjustment allows the guide member 130 to abut against the guide groove 230, ensuring the stability of the connection between the first housing 100 and the second housing 200 and preventing loosening between them. This prevents natural light from easily entering the first connection hole 110 through any loose gaps and affecting the detection reading of the photon counter 120.

[0041] In this embodiment, as Figure 3 , Figure 6 and Figure 7 As shown, the guide member 130 is threadedly connected to the first housing 100, with one end extending into the guide groove 230 and abutting against the second housing 200. This improves the stability of the connection between the first housing 100 and the second housing 200, and allows for the adjustable replacement of the guide member 130. In practical applications, the specific structures of the guide groove 230 and the guide member 130 can be set according to actual usage needs. For example, the guide groove 230 can be set as a "T"-shaped groove, and the guide member 130 can be set as a corresponding "T"-shaped structure. The number of guide members can also be set according to needs, and there is no limitation here. The installation and connection method of the guide member 130 can also be changed according to actual usage needs, such as using snap-fit ​​or interference fit for connection, and there is no limitation here.

[0042] In some embodiments, the upper inner side of the first housing 100 is provided with a first step portion 140, and the side of the second housing 200 is provided with a corresponding second step portion 240 that can abut against the first step portion 140. By providing the first step portion 140 and the second step portion 240, when the second housing 200 moves upward relative to the first housing 100, the abutment between the first step portion 140 and the second step portion 240 can limit the maximum stroke position of the second housing 200 relative to the first housing 100, preventing the second housing 200 from moving upward relative to the first housing 100 and detaching from the first housing 100, thereby improving the stability and reliability of the connection between them.

[0043] In this embodiment, as Figure 4 and Figure 8As shown, the upper inner side of the first housing 100 is provided with a first stepped portion 140, and correspondingly, the middle position of the second housing 200 is provided with a second stepped portion 240. When the present invention switches from a detection state to a non-detection state, the second housing 200 moves upward relative to the first housing 100 until the second stepped portion 240 abuts against the first stepped portion 140. At this time, the first connecting hole 110 and the second connecting hole 220 are completely misaligned, and the second housing 200 covers the first connecting hole 110. The abutment between the first stepped portion 140 and the second stepped portion 240 restricts the second housing 200 from continuing to move upward, preventing it from moving away from the first housing 100. In practical applications, the positions of the first stepped portion 140 and the second stepped portion 240 can be set according to the travel distance required for the second housing 200 to move relative to the first housing 100. This will be understood by those skilled in the art, and no limitation is made here.

[0044] In some embodiments, an elastic element 150 is provided between the first housing 100 and the second housing 200. The elastic element 150 enables the second housing 200 to move upward and reset. By providing the elastic element 150, when the second housing 200 moves downward relative to the first housing 100, the elastic element 150 is compressed. After the detection is completed, the housing cover plate 300 moves upward, and the second housing 200 can achieve upward movement and reset through the elastic element 150. Its structure is simple, facilitates the reset of the second housing 200, and reduces the size of the invention.

[0045] In this embodiment, as Figure 2 and Figure 6 As shown, an elastic element 150 is provided between the lower end of the first housing 100 and the lower end of the second housing 200. When the housing cover plate 300 pushes the second housing 200 downward relative to the first housing 100, it compresses the elastic element 150. When the housing cover plate 300 moves upward, the second housing 200 moves upward and resets under the action of the elastic element 150. In practical applications, in addition to the elastic element 150, a driver can also be provided to move the second housing 200 upward for reset. The connection method of the elastic element 150 can also be changed according to actual usage needs, and is not limited here.

[0046] In some embodiments, the elastic element 150 is a spring. The lower end of the first housing 100 is provided with an upwardly protruding connecting boss 160, and the lower end of the second housing 200 is provided with an upwardly recessed third connecting hole 250. One end of the elastic element 150 is sleeved on the connecting boss 160 and abuts against the bottom of the connecting boss 160, while the other end of the elastic element 150 extends into the third connecting hole 250 and abuts against the bottom of the third connecting hole 250. By setting the elastic element 150 as a spring and connecting its two ends to the connecting boss 160 and the third connecting hole 250 respectively, the installation and connection of the elastic element 150 can be facilitated, and the stability of its connection can be improved. At the same time, when the second housing 200 moves downward relative to the first housing 100 to compress the elastic element 150, the connecting boss 160 can extend into the third connecting hole 250, improving the stability and reliability of the movement between the second housing 200 and the first housing 100.

[0047] In practical applications, the elastic element 150 can be made of other elastic materials or sheet materials in addition to springs. Besides the connecting boss 160 and the third connecting hole 250, the elastic element 150 can also be connected by other connection methods, which are not limited here.

[0048] In some embodiments, the lower end of the housing cover plate 300 is provided with a downwardly protruding annular protrusion 320, and the upper end of the first housing 100 is provided with an annular connecting groove 170 for the annular protrusion 320 to be inserted. By providing the annular protrusion 320 and the annular connecting groove 170, the housing cover plate 300 covers the second housing 200 and pushes it downward. The annular protrusion 320 is inserted into the annular connecting groove 170, so that the housing cover plate 300 cooperates with the second housing 200 and the first housing 100 respectively to form a double-layer dark box structure, which has a better light-shielding effect. When the annular protrusion 320 is inserted into the annular connecting groove 170, a multi-layer structure is formed at the connection between the housing cover plate 300 and the first housing 100, which can enhance the light-shielding and sealing effect, so that the photon counter 120 has a better detection environment, and further improve the detection accuracy of the present invention.

[0049] In this embodiment, as Figure 3 and Figure 6As shown, the housing cover plate 300 is also provided with a downwardly annular protrusion forming an abutment portion 350. The upper end of the second housing 200 is provided with a third stepped portion 260 that can abut against the abutment portion 350. When the housing cover plate 300 moves downward relative to the first housing 100, the abutment portion 350 first abuts against the third stepped portion 260 and pushes the second housing 200 downward. Subsequently, the annular protrusion portion 320 is inserted into the annular connecting groove 170 to connect the housing cover plate 300 with the first housing 100. The connection between the housing cover plate 300, the first housing 100, and the second housing 200 forms a multi-layer structure, enhancing the light-shielding and sealing effect. Of course, in actual applications, the specific structural shape of the annular protrusion portion 320 and the annular connecting groove 170 is not limited to this and can be changed according to actual usage needs, which is not restricted here.

[0050] In some embodiments, a sealing ring 171 is provided within the annular connecting groove 170. By providing the sealing ring 171, the sealing effect when the annular protrusion 320 is connected to the annular connecting groove 170 can be further enhanced, thereby improving the sealing performance of the connection between them.

[0051] In this embodiment, as Figure 3 As shown, a sealing ring 171 is provided in the annular connecting groove 170. When the annular protrusion 320 is inserted into the annular connecting groove 170, it compresses the sealing ring 171, improving the sealing performance between the housing cover plate 300 and the first housing 100. In practical applications, the sealing ring 171 can be set according to actual usage needs, and there is no limitation here.

[0052] In some embodiments, the upper end of the housing cover 300 is provided with a connecting seat 330, and the lower end of the connecting seat 330 is connected to the clearance hole 310. A dropper assembly 340 is detachably provided on the connecting seat 330. The dropper assembly 340 can be connected to an external luminescent liquid delivery device and can add luminescent liquid to the reaction cup 1. By providing the connecting seat 330 and the detachable dropper assembly 340, when the first connecting hole 110 and the second connecting hole 220 are fully connected, luminescent liquid can be added to the reaction cup 1 through the dropper assembly 340, realizing the detection of the real-time luminescence in the reaction cup 1. This makes the present invention applicable to chemiluminescence immunoassay detection with different dropper modes, improving its applicability.

[0053] In this embodiment, as Figure 4 and Figure 8As shown, the housing cover 300 is provided with a connecting seat 330 and a dropper assembly 340. Existing chemiluminescence immunoassays can be roughly divided into two types: delayed luminescence detection, in which luminescent liquid is added to the reaction cup 1 and then placed in a dark chamber for detection and reading; and instantaneous luminescence detection, in which luminescent liquid is added to the reaction cup 1 after being placed in a dark chamber for detection and reading. The housing cover 300, which is provided with the connecting seat 330 and the dropper assembly 340, can be used for the above two types of chemiluminescence immunoassays. When used for delayed luminescence detection, the dropper assembly 340 can be disassembled and its installation position sealed to perform delayed luminescence detection as described above. When used for instantaneous luminescence detection, the dropper assembly 340 is connected to an external luminescent liquid delivery device. After the housing cover 300 is placed on the first housing 100, the upper end of the reaction cup 1 extends into the clearance hole 310, and the dropper assembly 340 can perform instantaneous luminescence detection as described above by adding luminescent liquid to the reaction cup 1. In practical applications, the specific structure of the connector 330 and the dripping assembly 340 can be set according to the actual needs of use, and there are also various ways to disassemble them, such as by threaded connection, snap-fit, etc. The number of dripping assemblies 340 can also be set according to the actual needs of use, and there is no limitation here.

[0054] A chemiluminescence immunoassay analyzer (not shown in the figure) according to a second aspect of the present invention includes a chemiluminescence immunoassay detection dark chamber according to the first aspect of the present invention described above.

[0055] According to the second aspect of the present invention, the chemiluminescence immunoassay analyzer, by employing the above-described chemiluminescence immunoassay detection dark chamber, enables the chemiluminescence immunoassay analyzer to achieve better luminescence detection effect, thereby achieving higher detection accuracy and improving the reliability of its detection results.

[0056] Since other components of the chemiluminescence immunoassay analyzer of this invention are known to those skilled in the art, they will not be described in detail here.

[0057] The embodiments of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present invention.

Claims

1. A chemiluminescent immunoassay detection dark box, characterized in that: include: A first shell (100), the upper end of the first shell (100) being open, and a side edge of the first shell (100) being provided with a first connection hole (110) corresponding to the photon counter (120); a second shell (200), the second shell (200) being movably inserted into the upper opening of the first shell (100); a cup placement hole (210) for placing a reaction cup (1) in the upper end of the second shell (200); a second connecting hole (220) communicating with the lower end of the cup placement hole (210) being provided on the side of the second shell (200); the second shell (200) being capable of moving up and down relative to the first shell (100); the first connecting hole (110) being capable of communicating with the second connecting hole (220); the photon counter (120) being capable of detecting the luminescence of the reaction cup (1) in the second connecting hole (220) through the first connecting hole (110); and the second shell (200) being capable of shielding the first connecting hole (110); a shell cover plate (300), wherein a relief hole (310) for the reaction cup (1) to extend into is provided at the lower end of the shell cover plate (300), and the shell cover plate (300) is capable of shielding the upper end of the second shell (200); A guide structure is provided between the first shell (100) and the second shell (200), the guide structure comprising a guide groove (230) and a guide member (130), the guide groove (230) being provided on a side of the second shell (200), the guide member (130) being connected to the first shell (100) by means of a thread and being capable of cooperating with the guide groove (230), an elastic member (150) being provided between the first shell (100) and the second shell (200), the elastic member (150) being a spring, and the first shell ( The lower end of the second shell (100) is provided with a connecting boss (160) which is protruding upward, and the lower end of the second shell (200) is provided with a third connecting hole (250) which is recessed upward, one end of the elastic member (150) is sleeved on the connecting boss (160) and abuts against the bottom of the connecting boss (160), and the other end of the elastic member (150) extends into the third connecting hole (250) and abuts against the bottom of the third connecting hole (250), and the elastic member (150) can move the second shell (200) upward to reset.

2. The chemiluminescent immunoassay detection dark box according to claim 1, characterized in that: A first step portion (140) is provided on the inner side of the upper end of the first shell (100), and a second step portion (240) capable of abutting against the first step portion (140) is correspondingly provided on the side edge of the second shell (200).

3. The chemiluminescent immunoassay detection dark box according to claim 1, characterized in that: The lower end of the housing cover plate (300) is provided with an annular protrusion (320) that protrudes downwards, and the upper end of the first housing (100) is provided with an annular connection groove (170) for inserting the annular protrusion (320).

4. The chemiluminescent immunoassay detection dark box according to claim 3, characterized in that: A sealing ring (171) is provided in the annular connecting groove (170).

5. The chemiluminescent immunoassay detection dark box according to claim 1, characterized in that: A connecting seat (330) is provided at the upper end of the shell cover (300), and the lower end of the connecting seat (330) is connected to the avoidance hole (310). A liquid drop assembly (340) is detachably provided on the connecting seat (330), and the liquid drop assembly (340) can be connected to an external luminescent liquid delivery device, and the liquid drop assembly (340) can drip luminescent liquid into the reaction cup (1).

6. A chemiluminescent immunoassay analyzer, characterized in that: It comprises a chemiluminescent immunoassay detection dark box according to any one of claims 1 to 5.

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