Chemiluminescent immunoassay analyzer and its reading device

Abstract

The present invention discloses a chemiluminescent immunoassay analyzer and a reading device thereof. The chemiluminescent immunoassay reading device comprises a frame, a reading component, an action platform and a driving mechanism arranged on the frame; the reading component comprises a photon counter, a first shell and a second shell movably inserted on the first shell, the second shell is respectively provided with a cup placement hole for placing a detection cup and a photometric hole connected to the lower end of the cup placement hole, the first shell is provided with a photometric connection hole, the photon counter is connected to the photometric connection hole, the second shell can move up and down relative to the first shell, the photometric hole and the photometric connection hole can be connected, the photon counter can detect the luminescence of the detection cup in the photometric hole through the photometric connection hole, and the second shell can cover the photometric connection hole; the action platform can move and cover the upper end of the second shell; the driving mechanism is drivingly connected to the first shell and / or the action platform. The detection reading effect of the present invention is good.

Description

Technical Field

[0001] The invention relates to the field of medical detection, and in particular to a chemiluminescent immunoassay analyzer and a reading device thereof. Background Art

[0002] Chemiluminescent immunoassay is an instrument that uses chemiluminescent immunoassay technology and reaction principles to qualitatively or quantitatively detect analytes in human serum, plasma or other body fluid samples, and is used to assist in the diagnosis of related diseases. Chemiluminescent immunoassay consists of two parts, namely the immune response system and the chemiluminescent analysis system. The immune response system marks the marker substance on the antigen or antibody, and after a specific immune reaction, an antigen-antibody complex is formed, and then the marker is detected to determine the analyte. The chemiluminescent analysis system uses the catalysis of the chemiluminescent substance or the oxidation of the oxidant to form an excited intermediate. When this excited intermediate returns to the stable ground state, it will emit photons at the same time, which are detected by the optical signal detector and converted into the concentration of the analyte by the computer data processing system.

[0003] When existing reading devices perform photon reading analysis, they generally need to be carried out in a darkroom environment, which has high requirements for the environment and makes the detection more troublesome. There are also some reading devices that use a shading structure to shade the photon reading part. This type of structure not only has a general shading effect, but also occupies a certain amount of space, resulting in unsatisfactory detection results and a large size, which is not convenient for promotion and application. Summary of the invention

[0004] The present invention aims to solve at least one of the technical problems existing in the prior art. To this end, the present invention provides a chemiluminescent immunoassay reading device, which has a good detection reading effect.

[0005] The present invention also provides a chemiluminescent immunoassay analyzer having the chemiluminescent immunoassay reading device.

[0006] According to the first aspect of the present invention, the chemiluminescent immunoassay reading device described in the embodiment includes a frame, a reading component, an action platform and a driving mechanism; the reading component includes a first shell, a second shell and a photon counter, the second shell is movably inserted on the first shell, the second shell is respectively provided with a cup placement hole for placing a detection cup and a photometric hole connected to the lower end of the cup placement hole, the first shell is provided with a photometric connecting hole, the photon counter is connected to the photometric connecting hole, the second shell can move up and down relative to the first shell, the photometric hole and the photometric connecting hole can be connected, the photon counter can detect the luminescence of the detection cup in the photometric hole through the photometric connecting hole, and the second shell can cover the photometric connecting hole; the action platform can move relative to the reading component and can cover the upper end of the second shell; the driving mechanism is arranged on the frame, and the driving mechanism is connected to the first shell and / or the action platform.

[0007] The chemiluminescent immunoassay reading device according to the embodiment of the present invention has at least the following beneficial effects: by setting a double-layer shell structure of a first shell and a second shell, the action platform can cooperate with the reading component to form a double-layer dark box structure with a good light shielding effect, and a photometric hole and a photometric connecting hole are set. When performing luminescent analysis detection, the action platform moves relative to the reading component and shields the upper end of the second shell, and the second shell moves downward relative to the first shell, so that the photometric hole and the photometric connecting hole are connected, which is convenient for the photon counter to detect the luminescence of the detection cup in the photometric hole through the photometric connecting hole; after completing the luminescent analysis detection, the second shell moves upward and resets, so that the photometric hole and the photometric connecting hole can be completely staggered, and the second shell blocks the photometric connecting hole, which can prevent the detection end of the photon counter from being exposed, thereby avoiding affecting the detection reading effect of the photon counter and improving the detection accuracy of the present invention.

[0008] According to some embodiments of the present invention, the reading assembly further includes an elastic member, and the two ends of the elastic member are respectively connected to the lower end of the first shell and the lower end of the second shell. By providing the elastic member, the upward movement and reset of the second shell can be facilitated, and at the same time, the photometric hole and the photometric connecting hole can be completely staggered, so that the second shell can cover the photometric connecting hole. The structure is simple and the volume of the reading assembly can be reduced.

[0009] According to some embodiments of the present invention, the action platform is provided with a first sealing portion and a second sealing portion, respectively, the upper end of the first shell is provided with an outer shell sealing groove for the first sealing portion to be inserted, and the upper end of the second shell is provided with an inner shell sealing step for the second sealing portion to abut against. By providing the outer shell sealing groove and the inner shell sealing step, when the first sealing portion is connected to the upper end of the first shell and the second sealing portion is connected to the upper end of the second shell, a multi-layer structure is formed at the connection, which can enhance the light-shielding sealing effect, so that the reading component obtains a better detection reading effect.

[0010] According to some embodiments of the present invention, the action platform is provided with a drip connection seat, a drip assembly, and a drip connection hole for the detection cup to extend into, the drip assembly is detachably arranged on the drip connection seat, the drip connection seat is connected to the drip connection hole, the drip assembly can be connected to an external luminescent liquid delivery device, and the drip assembly can drip luminescent liquid into the detection cup. By providing the drip connection seat and the drip assembly, after the action platform is covered and shielded at the upper end of the second shell, the luminescent chemical liquid can be dripped into the detection cup through the drip assembly, and the instant chemiluminescence in the detection cup can be detected, so that the present invention can be applied to detection in different drip modes, thereby improving its applicability.

[0011] According to some embodiments of the present invention, the action platform is provided with a liquid extraction joint assembly, the liquid extraction joint assembly includes a liquid extraction tube that can be inserted into the detection cup, and the liquid extraction joint assembly can be connected to an external suction device. By providing a liquid extraction tube, the waste liquid in the detection cup after the detection is completed is sucked out by connecting the liquid extraction tube to an external suction device, which can avoid pollution caused by leakage of waste liquid, and at the same time can reduce manual labor and improve the degree of automation.

[0012] According to some embodiments of the present invention, the liquid extraction joint assembly further includes a cup-removing member sleeved on the liquid extraction tube, and the cup-removing member can lift the detection cup on the second shell from the cup-placing hole. By providing the cup-removing member to lift the detection cup on the second shell from the cup-placing hole, it is possible to facilitate the next detection and cup placement, reduce manual labor, and improve the degree of automation.

[0013] According to some embodiments of the present invention, the rack is provided with a cup removal detection component, which can detect the presence of the detection cup on the cup removal member. By setting the cup removal detection component to detect whether the detection cup is extracted from the cup removal member, it is possible to avoid the cup removal member from performing the next cup removal when there is still a detection cup on it, thereby avoiding the occurrence of cup removal failures and improving the degree of intelligence of the present invention.

[0014] According to some embodiments of the present invention, the driving mechanism includes a synchronous belt drive assembly connected to the first housing and a screw drive assembly connected to the action platform, the synchronous belt drive assembly can drive the reading assembly to move horizontally, and the screw drive assembly can drive the action platform to move vertically. By arranging a synchronous belt drive assembly to drive the reading assembly to move and arranging a screw drive assembly to drive the action platform to move, the driving stability and accuracy can be improved, and the structure is simple, which can reduce costs and reduce the volume of the present invention.

[0015] According to some embodiments of the present invention, the frame is provided with a position detection component, and the position detection component can detect the position of the reading component and / or the action platform. By setting the position detection component to detect the position of the reading component and / or the action platform, it is possible to avoid the reading component and / or the action platform from operating in an incorrect position, thereby avoiding the occurrence of faults, ensuring the accuracy of the moving position of the reading component and / or the action platform, and improving the degree of intelligence of the present invention.

[0016] The chemiluminescent immunoassay analyzer according to the second aspect of the present invention comprises the chemiluminescent immunoassay reading device according to the first aspect of the present invention.

[0017] The chemiluminescent immunoassay analyzer according to the embodiment of the present invention has at least the following beneficial effects: by adopting the above-mentioned chemiluminescent immunoassay reading device, the chemiluminescent immunoassay analyzer can have a better luminescent detection reading effect, can improve the reliability of its detection results, and at the same time has a small size and reduces the occupied space. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The above and / or additional aspects and advantages of the present invention will become apparent and easily understood from the description of the embodiments in conjunction with the following drawings, in which:

[0019] Figure 1 This is a schematic diagram of the exploded structure of the chemiluminescent immunoassay reader according to the first aspect of the present invention;

[0020] Figure 2 for Figure 1 One of the front cross-sectional structural schematic diagrams of the chemiluminescent immunoassay reader;

[0021] Figure 3 for Figure 2 A schematic diagram of the left side cross-sectional structure of the chemiluminescent immunoassay reader;

[0022] Figure 4 for Figure 3 A magnified schematic diagram of part A;

[0023] Figure 5 for Figure 2 A schematic diagram of the top view of the chemiluminescent immunoassay reading device;

[0024] Figure 6 for Figure 1 The second schematic diagram of the front cross-sectional structure of the chemiluminescent immunoassay reading device;

[0025] Figure 7 for Figure 6 A magnified schematic diagram of part B;

[0026] Figure 8 for Figure 6 A schematic diagram of the left side cross-sectional structure of the chemiluminescent immunoassay reader;

[0027] Fig. 9 for Figure 8 Enlarged schematic diagram of part C.

[0028] Reference numerals:

[0029] Rack 100, cup removal detection assembly 110, cup body collection box 120, dripper collection box 130, first guide rail assembly 140, second guide rail assembly 150;

[0030] Reading assembly 200, first shell 210, photometric connecting hole 211, shell sealing groove 212, connecting boss 213, second shell 220, cup placing hole 221, photometric hole 222, inner shell sealing step 223, spring connecting hole 224, photon counter 230, elastic member 240, cup removing piece 250, and snap-in notch 251;

[0031] The action platform 300, the first sealing part 310, the second sealing part 320, the drip connection seat 330, the drip assembly 340, the drip connection hole 350, the liquid extraction joint assembly 360, the liquid extraction tube 361, and the cup removal member 362;

[0032] Driving mechanism 400, synchronous belt driving assembly 410, first driver 411, synchronous belt 412, screw driving assembly 420, second driver 421, screw 422, screw nut 423;

[0033] Control component 500 and detection cup 1. DETAILED DESCRIPTION

[0034] Embodiments of the present invention are described in detail below, examples of which are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and cannot be understood as limiting the present invention.

[0035] In the description of the present invention, it should be understood that descriptions involving orientations, such as up, down, front, back, left, right, etc., and orientations or positional relationships indicated are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0036] If the first and second are described, they are only used to distinguish the technical features and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features or implicitly indicating the sequence of the indicated technical features.

[0037] In the description of the present invention, unless otherwise clearly defined, terms such as setting, installing, connecting, etc. should be understood in a broad sense, and technicians in the relevant technical field can reasonably determine the specific meanings of the above terms in the present invention in combination with the specific content of the technical solution.

[0038] Reference Figure 1 and Figure 2 A chemiluminescent immunoassay reading device includes a frame 100, a reading assembly 200, an action platform 300 and a driving mechanism 400; the reading assembly 200 includes a first shell 210, a second shell 220 and a photon counter 230, the second shell 220 is movably inserted on the first shell 210, and the second shell 220 is respectively provided with a cup placement hole 221 for placing a detection cup 1 and a photometric hole 222 connected to the lower end of the cup placement hole 221, the first shell 210 is provided with a photometric connection hole 211, and the photon counter 230 is connected at the photometric connection hole 211 The second shell 220 can move up and down relative to the first shell 210, the photometric hole 222 and the photometric connecting hole 211 can be connected, the photon counter 230 can detect the light emission of the detection cup 1 in the photometric hole 222 through the photometric connecting hole 211, and the second shell 220 can cover the photometric connecting hole 211; the action platform 300 can move relative to the reading component 200 and can cover the upper end of the second shell 220; the driving mechanism 400 is arranged on the frame 100, and the driving mechanism 400 is connected to the first shell 210 and / or the action platform 300.

[0039] By setting a double-layer shell structure of the first shell 210 and the second shell 220, the action platform 300 can cooperate with the reading component 200 to form a double-layer dark box structure, which has a good light shielding effect. In addition, the photometric hole 222 and the photometric connecting hole 211 are set. When performing luminescence analysis and detection, the action platform 300 moves relative to the reading component 200 and shields the upper end of the second shell 220, and the second shell 220 moves downward relative to the first shell 210, so that the photometric hole 222 is connected with the photometric connecting hole 211, which facilitates the photon counter 230 to measure the photometric hole 222 through the photometric connecting hole 211. 2 to detect the luminescence of the detection cup 1; after completing the luminescence analysis detection, the second shell 220 moves upward and resets, so that the photometric hole 222 and the photometric connecting hole 211 can be completely staggered, and the second shell 220 blocks the photometric connecting hole 211, which can prevent the detection end of the photon counter 230 from being exposed, thereby avoiding affecting the detection reading effect of the photon counter 230 and improving the detection accuracy of the present invention; at the same time, the sleeve structure of the first shell 210 and the second shell 220 can reduce the volume of the reading component 200, so that the volume of the present invention is small and the placement space is saved.

[0040] In this embodiment, if Figure 2 and Figure 3 As shown, the present invention is in a non-detection reading state, the second housing 220 is movably inserted on the first housing 210, the photometric hole 222 and the photometric connecting hole 211 are in a completely staggered state, and the outer wall of the second housing 220 blocks the photometric connecting hole 211, so that the detection head of the photon counter 230 is in a dark environment. During detection, a chemiluminescent liquid is added to the detection cup 1 that has been processed in the early stage, and a control component 500 is provided on the frame 100. The control component 500 controls the driving mechanism 400 to drive the reading component 200 and / or the action platform 300 to move, so that the action platform 300 is covered and shielded at the upper end of the second housing 220. , the action platform 300 and the second shell 220 form an inner dark box structure, the second shell 220 moves downward relative to the first shell 210, and the photometric hole 222 gradually communicates with the photometric connecting hole 211. At this time, since the action platform 300 covers and shields the upper end of the second shell 220, after the photometric hole 222 is connected with the photometric connecting hole 211, the detection head of the photon counter 230 is still in a dark environment; the second shell 220 moves downward relative to the first shell 210 until the photometric hole 222 is completely connected with the photometric connecting hole 211. At this time, the action platform 300 covers the upper end of the first shell 210 to form an outer dark box structure, such as Figure 6 , Figure 8 and Fig. 9 As shown, the present invention is in a detection reading state, the photometric hole 222 and the photometric connecting hole 211 are in a completely connected state, the object to be detected in the detection cup 1 reacts immune and starts to emit light, and the photon counter 230 measures the number of photons and analyzes and processes and feeds back the results.

[0041] In actual application, the movement of the second shell 220 can also be achieved by setting a driving device or other structures. The photon counter 230 is a commonly used light-emitting detection element in this field. It and the control component 500 can be selected and set according to actual use needs, which can be understood by those skilled in the art. At the same time, the specific structure of the action platform 300 is not limited here, as long as it can cover the upper end of the second shell 220. The specific structure of the driving mechanism 400, the driving connection method, the specific structure of the reading component 200, etc. are not described in detail here, and will be described in detail below.

[0042] In some embodiments, the reading assembly 200 further includes an elastic member 240, and two ends of the elastic member 240 are respectively connected to the lower end of the first housing 210 and the lower end of the second housing 220. By providing the elastic member 240, the upward movement and reset of the second housing 220 can be facilitated, and at the same time, the photometric hole 222 and the photometric connecting hole 211 can be completely staggered, so that the second housing 220 can cover the photometric connecting hole 211, and the structure is simple, which can reduce the volume of the reading assembly 200.

[0043] In this embodiment, if Figure 3 and Figure 4 As shown, the elastic member 240 is a spring, and the lower end of the second shell 220 is provided with a spring connecting hole 224 formed by an upward depression, and the lower end of the first shell 210 is provided with a connecting boss 213 formed by an upward protrusion. One end of the elastic member 240 is sleeved on the connecting boss 213 and abuts against the bottom of the connecting boss 213, and the other end thereof extends into the spring connecting hole 224 and abuts against the bottom of the spring connecting hole 224. When the second shell 220 moves downward, the elastic member 240 is compressed, and at the same time, the connecting boss 213 extends into the spring connecting hole 224; when the action platform 300 moves upward relative to the reading component 200, the second shell 220 is reset under the action of the elastic member 240, so that the photometric hole 222 is completely staggered with the photometric connecting hole 211, and its structure is simple and the connection is stable. In actual application, in addition to the elastic member 240, a driver can also be provided to reset the second shell 220. In addition to the spring, a spring or other elastic material can also be provided. The connection method of the elastic member 240 can also be changed according to actual use needs and is not limited here.

[0044] In some embodiments, the action platform 300 is provided with a first sealing portion 310 and a second sealing portion 320, respectively, the upper end of the first shell 210 is provided with an outer shell sealing groove 212 for inserting the first sealing portion 310, and the upper end of the second shell 220 is provided with an inner shell sealing step 223 for abutting the second sealing portion 320. By providing the outer shell sealing groove 212 and the inner shell sealing step 223, when the first sealing portion 310 is connected to the upper end of the first shell 210 and the second sealing portion 320 is connected to the upper end of the second shell 220, a multi-layer structure is formed at the connection, which can enhance the light-shielding sealing effect, so that the reading component 200 obtains a better detection reading effect.

[0045] In this embodiment, if Figure 5 , Figure 6 and Figure 7 As shown, the outer shell sealing groove 212 is an annular groove structure, and the inner shell sealing step portion 223 is an annular step structure. Correspondingly, the first sealing portion 310 and the second sealing portion 320 are both annular protrusion structures. When the action platform 300 moves downward relative to the reading component 200, the second sealing portion 320 first abuts against the inner shell sealing step portion 223 to form a sealed connection and pushes the second shell 220 to move downward. Subsequently, the first sealing portion 310 is inserted into the outer shell sealing groove 212 to form a sealed connection, so that the connection between the action platform 300 and the reading component 200 forms a multi-layer structure to enhance the light-shielding sealing effect. Of course, in actual application, the specific structure of the outer shell sealing groove 212 and the inner shell sealing step portion 223 is not limited to this, and can also be changed according to actual use needs. At the same time, the specific shapes of the first sealing portion 310 and the second sealing portion 320 can also be changed accordingly. Moreover, the connection between the first sealing portion 310 and the outer shell sealing groove 212 and the connection between the second sealing portion 320 and the inner shell sealing step portion 223 can be provided with a sealing rubber ring to improve the sealing effect, which is not limited here.

[0046] In some embodiments, the action platform 300 is provided with a drip connection seat 330, a drip assembly 340 and a drip connection hole 350 for the detection cup 1 to extend into, and the drip assembly 340 is detachably arranged on the drip connection seat 330, and the drip connection seat 330 is sealed and connected at the drip connection hole 350. By providing the drip connection seat 330 and the drip assembly 340, after the action platform 300 is covered and shielded on the upper end of the second shell 220, the luminescent chemical liquid can be dripped into the detection cup 1 through the drip assembly 340, and the instant chemiluminescence in the detection cup 1 can be detected, so that the present invention can be applied to detection in different drip modes, thereby improving its applicability.

[0047] In this embodiment, if Figure 6 and Figure 7As shown, the action platform 300 is provided with a drop connection seat 330, a drop assembly 340 and a drop connection hole 350. The existing chemiluminescent immunoassay can be roughly divided into two types, namely, delayed luminescence detection in which a chemiluminescent liquid is dripped into the test cup 1 and then placed in a dark room for reading, and instant luminescence detection in which a chemiluminescent liquid is dripped into the test cup 1 after the test cup 1 is placed in a dark room for instant reading. The action platform 300 provided with the drop connection seat 330, the drop assembly 340 and the drop connection hole 350 can be applicable to the above two chemiluminescent immunoassays. When used for delayed luminescence detection, the drop assembly 340 is disassembled and its installation position is sealed, and then the delayed luminescence detection can be performed as described above; when used for instant luminescence detection, the drop assembly 340 is connected to an external chemiluminescent liquid device, and after the action platform 300 is connected to the reading assembly 200, the upper end of the test cup 1 extends into the drop connection hole 350, and the drop assembly 340 can perform the instant luminescence detection as described above on the chemiluminescent liquid dripped into the test cup 1. In actual application, the specific structure of the drip connection seat 330 and the drip assembly 340 can be set according to actual use needs, and there are also various ways to disassemble them, such as through threaded connection, snap connection, etc. The number of settings of the drip assembly 340 can also be set according to actual use needs, and there is no restriction here.

[0048] In some embodiments, a liquid extraction joint assembly 360 is provided on the action platform 300, and the liquid extraction joint assembly 360 includes a liquid extraction tube 361 that can be inserted into the detection cup 1, and the liquid extraction joint assembly 360 can be connected to an external suction device. By providing the liquid extraction tube 361, the waste liquid in the detection cup 1 after the detection is completed is sucked out by connecting the liquid extraction tube 361 to the external suction device, which can avoid pollution caused by leakage of waste liquid, and at the same time can reduce manual labor and improve the degree of automation.

[0049] In this embodiment, if Figure 6 As shown, a liquid extraction joint assembly 360 is provided on the action platform 300, and the action platform 300 moves downward relative to the reading assembly 200, so that the liquid extraction tube 361 extends into the detection cup 1, and the waste liquid in the detection cup 1 is sucked out by an external suction device. In actual application, the specific structure of the liquid extraction joint assembly 360 can be set accordingly according to actual use needs, and is not limited here.

[0050] In some embodiments, the liquid extraction joint assembly 360 further includes a cup removal member 362 sleeved on the liquid extraction tube 361, and the cup removal member 362 can lift the detection cup 1 on the second housing 220 from the cup placement hole 221. By providing the cup removal member 362 to lift and detach the detection cup 1 on the second housing 220 from the cup placement hole 221, it is possible to facilitate the next detection and cup placement, reduce manual labor, and improve the degree of automation.

[0051] In this embodiment, if Figure 2 and Figure 6 As shown, a cup-removing member 362 is sleeved on the liquid-drawing tube 361. The cup-removing member 362 can be made of elastic material and has an inverted cone structure. When the liquid-drawing tube 361 moves downward and extends into the detection cup 1, the inverted cone-shaped cup-removing member 362 simultaneously extends into the detection cup 1. Due to its inverted cone structure, the cup-removing member 362 can be engaged with the upper end of the detection cup 1 when moving downward. When the action platform 300 moves upward relative to the reading component 200, the cup-removing member 362 lifts the engaged detection cup 1 from the cup placing hole 221, thereby realizing the removal of the detection cup 1 from the reading component 200.

[0052] In this embodiment, Figure 2 and Figure 5 As shown, the reading component 200 is further provided with a cup removing piece 250, and the cup removing piece 250 is provided with a clamping notch 251. The cup removing piece 362 can be moved relative to the cup removing piece 250 to clamp the clamping notch 251 of the cup removing piece 250 on the cup removing piece 362 with the detection cup 1 or on the detection cup 1. Then, the cup removing piece 362 is moved upward relative to the cup removing piece 250 to clamp the detection cup 1 on the cup removing piece 362 through the clamping notch 251 and detach it from the cup removing piece 362, so as to realize the cup removing operation of the cup removing piece 362. Of course, in actual application, in addition to the cup removing piece 362 and the cup removing piece 250 structure of the above structure, the cup removing piece 362 can also be set as a robot to grab and detach the detection cup 1 on the reading component 200. The specific structure of the cup removing piece 362 can be set accordingly according to the actual use needs, and is not limited here.

[0053] In this embodiment, if Figure 2 As shown, the rack 100 is also provided with a cup body collection box 120 for placing the test cup 1 separated from the cup removal member 362, so as to facilitate the storage and placement of the test cup 1 after use, and facilitate subsequent treatment thereof. At the same time, the rack 100 is also provided with a dripper collection box 130 for placing the used chemical dripper, so as to facilitate subsequent treatment of the used chemical dripper.

[0054] In some embodiments, the rack 100 is provided with a cup-removing detection assembly 110, which can detect the presence of the detection cup 1 on the cup-removing member 362. By providing the cup-removing detection assembly 110 to detect whether the detection cup 1 is extracted from the cup-removing member 362, it is possible to avoid the cup-removing member 362 from performing the next cup-removing operation when there is still the detection cup 1 on it, thereby avoiding the occurrence of cup-removing failures, and at the same time improving the degree of intelligence of the present invention.

[0055] In this embodiment, if Figure 2 and Figure 6As shown, a cup-removing detection assembly 110 is provided on the frame 100. The cup-removing detection assembly 110 includes an infrared sensor, which is arranged at a position corresponding to the cup-removing member 362. The infrared sensor detects the presence or absence of the detection cup 1 on the cup-removing member 362 through infrared rays to avoid malfunctions during the cup-removing process. In actual application, the specific structure of the cup-removing detection assembly 110 can be set accordingly according to actual use needs, and in addition to the infrared sensor, the cup-removing detection assembly 110 can also include a pressure sensor or other types of detection elements connected to the cup-removing member 362, which is not limited here.

[0056] In some embodiments, the driving mechanism 400 includes a synchronous belt driving assembly 410 drivingly connected to the first housing 210 and a screw driving assembly 420 drivingly connected to the action platform 300. The synchronous belt driving assembly 410 can drive the reading assembly 200 to move horizontally, and the screw driving assembly 420 can drive the action platform 300 to move vertically. By setting the synchronous belt driving assembly 410 to drive the reading assembly 200 to move and setting the screw driving assembly 420 to drive the action platform 300 to move, the driving stability and accuracy can be improved, and the structure is simple, which can reduce the cost and reduce the volume of the present invention.

[0057] In this embodiment, if Figure 1 and Figure 2 As shown, the driving mechanism 400 is electrically connected to the control component 500, which includes a synchronous belt driving component 410 and a screw driving component 420. The synchronous belt driving component 410 includes a first driver 411 and a synchronous belt 412 driven and connected to the first driver 411. The first driver 411 and the synchronous belt 412 are both installed on the frame 100. The frame 100 is also provided with a first guide rail component 140. The reading component 200 is slidably set on the frame 100 through the first guide rail component 140 and is connected to the synchronous belt 412. The first driver 411 drives and drives the reading component 200 to move left and right along the direction of the first guide rail component 140 through the synchronous belt 412. The screw drive assembly 420 includes a second driver 421, a screw 422 drivingly connected to the second driver 421, and a screw nut 423 connected to the screw 422. The screw nut 423 is fixedly connected to the action platform 300. A second guide rail assembly 150 is also provided on the frame 100. The action platform 300 is slidably set on the frame 100 through the second guide rail assembly 150. The second driver 421 drives and drives the action platform 300 to move up and down along the direction of the second guide rail assembly 150 through the cooperation of the screw 422 and the screw nut 423, thereby realizing the mobile drive control of the reading assembly 200 and the action platform 300.

[0058] In actual application, in addition to the above-mentioned drive control forms, a manipulator may be provided to be connected to the motion platform 300 to control the motion platform 300 to move horizontally and vertically, or a cylinder drive or hydraulic drive may be provided. The specific drive form of the drive mechanism 400 may be set accordingly according to actual use needs, which can be understood by those skilled in the art and is not limited here.

[0059] In some embodiments, a position detection component (not shown in the figure) is provided on the frame 100, and the position detection component can detect the position of the reading component 200 and / or the action platform 300. By setting the position detection component to detect the position of the reading component 200 and / or the action platform 300, it is possible to avoid the reading component 200 and / or the action platform 300 from operating at an incorrect position, thereby avoiding the occurrence of faults, ensuring the accuracy of the moving position of the reading component 200 and / or the action platform 300, and improving the degree of intelligence of the present invention.

[0060] In this embodiment, the position detection component includes a photoelectric sensor, which is arranged at the corresponding stroke position of the reading component 200 and / or the action platform 300. The photoelectric sensor is used to detect whether the reading component 200 and / or the action platform 300 has moved to the specified position, so as to avoid malfunction when the reading component 200 and / or the action platform 300 has not moved to the action position to perform an action. In actual application, the specific structure of the position detection component can be set accordingly according to actual use needs, and in addition to the photoelectric sensor, the position detection component can also use detection elements such as pressure sensors, which are not limited here.

[0061] The chemiluminescent immunoassay analyzer (not shown in the figure) according to the second embodiment of the present invention comprises the chemiluminescent immunoassay reading device according to the first embodiment of the present invention.

[0062] The chemiluminescent immunoassay analyzer according to the embodiment of the present invention can have a better luminescent detection reading effect and improve the reliability of its detection results by adopting the above-mentioned chemiluminescent immunoassay reading device, while having a smaller size and reducing the occupied space.

[0063] Since other components of the chemiluminescent immunoassay analyzer according to the embodiment of the present invention are known to those skilled in the art, they will not be described in detail here.

[0064] The embodiments of the present invention are described in detail above with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments. Various changes can be made within the knowledge scope of ordinary technicians in the technical field without departing from the purpose of the present invention.

Claims

1. A chemiluminescent immunoassay reading device, characterized in that: include: Rack(100); The reading assembly (200) comprises a first shell (210), a second shell (220) and a photon counter (230), wherein the second shell (220) is movably inserted into the first shell (210), the second shell (220) is respectively provided with a cup placement hole (221) for placing a detection cup (1) therein and a photometric hole (222) connected to the lower end of the cup placement hole (221), the first shell (210) is provided with a photometric connection hole (211), and the photon counter (230) is provided with a photometric connection hole (211). The second housing (220) is connected to the photometric connection hole (211), the second housing (220) is movable up and down relative to the first housing (210), the photometric hole (222) and the photometric connection hole (211) are interlinked, the photon counter (230) is capable of detecting the light emission of the detection cup (1) in the photometric hole (222) through the photometric connection hole (211), and the second housing (220) is capable of shielding the photometric connection hole (211); an action platform (300), the action platform (300) being capable of moving relative to the reading component (200) and being capable of shielding the upper end of the second shell (220); A driving mechanism (400) is arranged on the frame (100), and the driving mechanism (400) is drivingly connected to the first shell (210) and / or the action platform (300); The action platform (300) is provided with a first sealing portion (310) and a second sealing portion (320), respectively; the upper end of the first shell (210) is provided with an outer shell sealing groove (212) for inserting the first sealing portion (310); the upper end of the second shell (220) is provided with an inner shell sealing step portion (223) for abutting the second sealing portion (320); the driving mechanism (400) comprises a synchronous belt driving component (410) drivingly connected to the first shell (210) and a screw driving component (420) drivingly connected to the action platform (300); the synchronous belt driving component (410) can drive the reading component (200) to move horizontally, and the screw driving component (420) can drive the action platform (300) to move vertically.

2. The chemiluminescent immunoassay reader according to claim 1, characterized in that: The reading component (200) further comprises an elastic member (240), and two ends of the elastic member (240) are respectively connected to the lower end of the first shell (210) and the lower end of the second shell (220).

3. The chemiluminescent immunoassay reader according to claim 1, characterized in that: The action platform (300) is provided with a drip connection seat (330), a drip assembly (340) and a drip connection hole (350) for the detection cup (1) to extend into; the drip assembly (340) is detachably arranged on the drip connection seat (330); the drip connection seat (330) is connected to the drip connection hole (350); the drip assembly (340) can be connected to an external luminescent liquid delivery device; and the drip assembly (340) can drip luminescent liquid into the detection cup (1).

4. The chemiluminescent immunoassay reader according to claim 1, characterized in that: The action platform (300) is provided with a liquid extraction joint assembly (360), the liquid extraction joint assembly (360) comprising a liquid extraction tube (361) capable of extending into the detection cup (1), and the liquid extraction joint assembly (360) can be connected to an external suction device.

5. The chemiluminescent immunoassay reader according to claim 4, characterized in that: The liquid extraction joint assembly (360) further comprises a cup removal member (362) sleeved on the liquid extraction tube (361), wherein the cup removal member (362) is capable of lifting the detection cup (1) on the second shell (220) from the cup placement hole (221).

6. The chemiluminescent immunoassay reader according to claim 5, characterized in that: The frame (100) is provided with a cup removal detection component (110), and the cup removal detection component (110) is capable of detecting the presence of the detection cup (1) on the cup removal member (362).

7. The chemiluminescent immunoassay reader according to claim 1, characterized in that: The frame (100) is provided with a position detection component, and the position detection component is capable of detecting the position of the reading component (200) and / or the action platform (300).

8. A chemiluminescent immunoassay analyzer, characterized in that: Comprising a chemiluminescent immunoassay reader according to any one of claims 1 to 7.

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