A tissue sample collection and separation device

Abstract

The present invention discloses a tissue sample collection and separation device, comprising a cup body, a cup cover and a plurality of inner cores; wherein, a plurality of inner core insertion ports are arranged on the outer periphery of the cup body, and the inner cores are pluggably inserted into the interior of the cup body through the inner core insertion ports; the cup cover is covered on the cup body to seal the cup body, and the cup cover can rotate in a state of covering the cup body; a liquid inlet channel and a liquid outlet channel are arranged on the cup cover, the liquid outlet channel is arranged at the center position of the cup cover, and the liquid inlet channel is arranged at a position close to the edge of the cup cover; by rotating the cup body, different inner cores are aligned with the liquid inlet channel. The above-mentioned biopsy tissue sample collection and separation device can collect tissue samples from different parts in different inner cores by rotating the cup body to make different inner cores correspond to the liquid inlet channels, and can realize the corresponding collection of tissue samples from different parts; and the design of the pluggable inner core facilitates the removal and detection of tissue samples after collection.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a tissue sample collection and separation device. Background Art

[0002] With the development of minimally invasive technology, endoscopic examinations and treatments are gradually increasing, and the collection of endoscopic resected tissue has always been a difficult problem that needs to be solved. The collection of resected tissue can be carried out by using the suction device of the endoscope to perform negative pressure suction, allowing the tissue to enter the suction channel through the suction cavity of the endoscope, and placing gauze at the suction channel to block the tissue, so as to collect it. However, if there are multiple pieces of tissue, the above collection method is easy to cause tissue confusion, which is very inconvenient. Therefore, it is very important to study a collection and separation device for endoscopic resected tissue under negative pressure suction.

[0003] A disposable tissue collector for endoscope suction is disclosed in the publication number CN206228370U, which includes a bottle body, a bottle cap, a gastroscope connecting catheter, and an aspirator connecting catheter. The bottle cap is rotatably connected to the bottle body, the gastroscope connecting catheter is connected to the bottle cap, and the aspirator connecting catheter is inserted into the bottom of the bottle body. The bottom end of the gastroscope connecting catheter is level with the bottle cap, the gastroscope connecting catheter is connected to the bottle body, and the gastroscope connecting catheter, the aspirator connecting catheter and the bottle cap are sealed; the lower part of the bottle body is a collection chamber, and the upper part of the bottle body is provided with multiple equally divided grids, wherein three-quarters of the continuous grids are collection grids, and a filter screen integrally provided with the grid is provided at the bottom end of each collection grid, and another quarter of the continuous grids are ventilation grids, and the ventilation grids and each collection grid are respectively connected to the gastroscope connecting catheter. This collector has a large collection capacity, and multiple collection grids can collect multiple specimens of the same patient, thereby avoiding the loss of specimens. However, after the samples are collected in the above-mentioned collection grid, tweezers are needed to remove the samples from the collection grid, which is not convenient for removing and testing the samples, and is also prone to causing confusion and contamination of the samples during the sample removal process. Summary of the invention

[0004] In order to solve the above technical problems, the present invention provides a tissue sample collection and separation device.

[0005] In order to achieve the above technical objectives, the present invention provides the following technical solutions:

[0006] A tissue sample collection and separation device comprises a cup body, a cup cover and a plurality of inner cores; wherein a plurality of inner core insertion openings are arranged on the outer periphery of the cup body, and the inner cores are pluggably inserted into the interior of the cup body through the inner core insertion openings;

[0007] The cup cover is placed on the cup body to seal the cup body, and the cup cover can rotate relative to the cup body in a state of covering the cup body;

[0008] The cup cover is provided with a liquid inlet channel and a liquid outlet channel, wherein the liquid outlet channel is arranged at the center of the cup cover and the liquid inlet channel is arranged near the edge of the cup cover; the cup body is rotated so that different inner cores are aligned with the liquid inlet channels.

[0009] Preferably, the inner core includes a connecting plate, a collecting box and a handle; the connecting plate is arc-shaped, the handle is arranged on the outer side of the connecting plate, and the collecting box is arranged on the inner side of the connecting plate.

[0010] Preferably, the collecting box includes a fan-shaped bottom surface and two rectangular side surfaces, and a plurality of filter holes are arranged in the fan-shaped bottom surface and / or the rectangular side surfaces.

[0011] Preferably, an elastic buckle is provided on both sides of the collection box, and the elastic buckle is connected to the inner side of the connecting plate; on the cup body, an inner core fixing groove is provided on both sides of each inner core insertion port, for cooperating with the elastic buckle of the inner core.

[0012] Preferably, the lower edge of the inner core insertion opening is close to the bottom of the cup body; the inner core is disposed close to the bottom of the cup body, and the height of the inner core exceeds 1 / 2 of the height of the cup body.

[0013] Preferably, the inner part of the cup body is a central area and a peripheral area for arranging the inner core, the peripheral area is divided into a plurality of inner core insertion areas for inserting the inner core and a plurality of spacing areas, and the inner core insertion areas and the spacing areas are alternately arranged.

[0014] Preferably, a guide baffle extending radially from the left and right sides of the inner core insertion port is provided inside the cup body, and the bottom of the U-shaped base is connected to the bottom of the cup body; a U-shaped base connected to the bottom edge of the inner core insertion port is also provided inside the cup body, and the bottom of the U-shaped base is connected to the bottom of the cup body.

[0015] Preferably, a serial number mark is provided on the outer wall of the cup body above each inner core insertion opening.

[0016] Preferably, the liquid inlet channel and the liquid outlet channel both penetrate the cup cover vertically;

[0017] One end of the liquid inlet channel extends toward the inside of the cup body and extends to a position higher than the upper edge of the inner core insertion opening, and the other end protrudes above the cup cover;

[0018] One end of the liquid outlet channel extends toward the inside of the cup body and to a position close to the bottom of the cup body, and the other end protrudes above the cup cover.

[0019] Preferably, a positioning portion is provided on the outer periphery of the cup cover, and the positioning portion is located on the same straight line as the liquid inlet channel and the liquid outlet channel.

[0020] The tissue sample collection and separation device provided by the present invention comprises a cup body, a cup cover and a plurality of pluggable inner cores. By rotating the cup body, different inner cores are made to correspond to liquid inlet pipes, and tissue samples from different parts can be collected in different inner cores, thereby realizing the corresponding collection of tissue samples from different parts. Moreover, the design of the pluggable inner core facilitates the removal and detection of tissue samples after collection, simplifies the operation, and is less likely to cause tissue sample contamination. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a schematic diagram of the overall structure of the biopsy tissue sample collection and separation device provided by the present invention;

[0022] Figure 2 yes Figure 1 A schematic diagram of the front view structure of the middle cup cover;

[0023] Figure 3 yes Figure 1 A schematic diagram of the top view of the structure of the middle cup cover;

[0024] Figure 4 yes Figure 1 A schematic diagram of the structure of the middle cup cover when viewed from above;

[0025] Figure 5 yes Figure 1 Schematic diagram of the combined state of the middle cup body and the inner core;

[0026] Figure 6 yes Figure 1 A schematic diagram of the top view of the structure of the middle cup body;

[0027] Figure 7 yes Figure 1 Schematic diagram of the three-dimensional structure of the middle cup body;

[0028] Figure 8 yes Figure 1 A schematic diagram of the top view of the structure of the middle inner core;

[0029] Fig. 9 yes Figure 1 Schematic diagram of the side view structure of the middle inner core. DETAILED DESCRIPTION

[0030] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0031] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it can be directly on the other element or indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or indirectly connected to the other element.

[0032] It should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "inside", "outside", etc., indicating the orientation or position relationship are based on the orientation or position relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0033] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of this application, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0034] like Figure 1 As shown, the biopsy tissue sample collection and separation device provided by the present invention comprises a cup cover 1, a cup body 2 and a plurality of inner cores 3. The cup cover 1 is a circular thin sheet, and the cup body 2 is a cylindrical shape. The cup cover 1 covers the circular cup body 2 and seals the cup body 2. The cup cover 1 can rotate relative to the cup body 2 while covering the cup body 2. A plurality of inner core insertion openings 25 are provided on the outer periphery of the cup body 2, and the plurality of inner cores 3 are pluggably arranged in the cup body 2 through the plurality of inner core insertion openings 25.

[0035] Specifically, Figure 2-4 As shown, the cup cover 1 is provided with a first channel 11 and a second channel 12, and the first channel 11 and the second channel 12 both penetrate the cup cover 1 in the vertical direction, and one end (such as Figure 2 The lower end shown in FIG. 1 extends toward the interior of the cup body 2, and the other end (as shown in FIG. Figure 2 The first channel 11 extends to one end of the cup body 2 (as shown in FIG. Figure 2 The second channel 12 extends to one end of the cup body 2 (as shown in the figure), and extends to a position close to the bottom of the cup body 2; Figure 2 The lower end shown in the figure) extends to a position higher than the upper edge of the inner core 3 inside the cup body 2, that is, higher than the upper edge of the inner core insertion port 20 of the cup body 2.

[0036] The first channel 11 is located at the center of the cup cover 1, and is used to extract the waste liquid in the cup body 2. The second channel 12 is located between the first channel 11 and the edge of the cup cover 1, and is arranged at a position close to the edge of the cup cover 1; and the arrangement position of the second channel 12 on the cup cover 1 corresponds to the arrangement area 20B of the multiple inner cores 3 inside the cup body 2.

[0037] A positioning portion 13 is provided on the outer periphery of the cup cover 1, and the positioning portion 13 is located on the same straight line as the first channel 11 and the second channel 12. When the cup cover 1 is rotated until the positioning portion 13 is aligned with one of the inner cores 3, the second channel 12 is located above the inner core 3, and is used to guide the waste liquid into the inner core 3. The positioning portion 13 can be a positioning protrusion as shown in the figure, and the shape of the positioning protrusion is not limited to a triangle; the positioning portion 13 can also be other obvious signs, such as a pointer image printed on the outer periphery of the cup cover 1.

[0038] A plurality of protrusions 14 are also provided on the outer circumference of the cup cover 1 to enhance the friction between the cup cover 1 and the hand and facilitate the rotation of the cup cover 1. The number of the protrusions 14 is not limited and can be any number.

[0039] An annular slot is provided at the lower end of the cup cover 1, and a plurality of protruding buckles 15 are provided on the side wall of the slot, and the plurality of buckles 15 are distributed along the outer circumference of the cup cover 1, and are used to cooperate with an annular flange 27 provided at the upper end of the cup body 2 to achieve the engagement of the cup cover 1 and the cup body 2, and when the cup cover 1 closes the cup body 2, the cup body 2 can rotate relative to the cup cover 1. The number of buckles 15 is not limited.

[0040] When in use, the above-mentioned biopsy tissue sample collection and separation device is connected to the suction pipe connected to the suction device of the biopsy device, wherein the first channel 11 is a liquid outlet channel, and the upper end of the first channel 11 is connected to the suction device and the waste liquid collection device; the second channel 12 is a liquid inlet channel, and the upper end of the liquid inlet channel is connected to the biopsy position through the suction pipe. Under the action of the suction device, the waste liquid sucked out from the biopsy position by the suction device enters the inner core 3 through the second channel 12, is sucked away from the first channel 11 after filtration, and enters the waste liquid collection device, and the tissue in the waste liquid is separated into the inner core 3. When the biopsy position changes, the cup body 2 can be rotated to replace the inner core 3 corresponding to the second channel 12, so that the tissue samples cut from different biopsy positions are separated into different inner cores 3.

[0041] like Figure 5As shown, the cup body 2 is a cylindrical shell with an open upper end, wherein the interior of the cup body 2 is divided into a central area 20A and a peripheral area 20B for arranging the inner core 3. Multiple inner cores 3 are evenly and pluggably arranged in the peripheral area 20B of the cup body 2. The inner core 3 is arranged near the bottom of the cup body 2, and the height of the inner core 3 exceeds 1 / 2 of the height of the cup body 2, preferably, it can exceed 3 / 4 of the height of the cup body 2. The above arrangement provides a larger tissue sample collection space for each inner core 3.

[0042] like Figure 6 and Figure 7 As shown, the cup body 2 is a cylindrical shape with one side open, and an annular flange 27 is provided on the outer wall of the upper end of the cup body 2 along the circumferential direction, which is used to cooperate with the buckle 15 on the cup cover 1 to achieve the engagement of the cup body 2 and the cup cover 1. In the process of inserting the upper end of the cup body 2 into the slot at the lower end of the cup cover 1, the annular flange 27 causes the buckle 15 to deform, and when the annular flange 27 exceeds the buckle 15, the annular flange 27 is restricted to the inner side of the buckle 15, so that the cup body 2 and the cup cover 1 are connected, and the cup body 2 can rotate relative to the cup cover 1 around the first channel 11.

[0043] A plurality of inner core insertion openings 25 are provided on the side of the outer periphery of the cup body 2, and an inner core fixing groove 26 is provided on both sides of each inner core insertion opening 25. In the cup body 2 provided in this embodiment, 6 inner core insertion openings 25 and 12 inner core fixing grooves 26 are provided. The number of inner cores 3 and the number of inner core insertion openings 25 can be changed according to actual needs.

[0044] like Figure 5 and Figure 6 As shown, the outer peripheral area 20B inside the cup body 2 corresponding to the inner core 3 is divided into a plurality of inner core insertion areas 21 for inserting the inner core 3 and a plurality of spacing areas 22, and the inner core insertion areas 21 and the spacing areas 22 are arranged alternately.

[0045] The inner core insertion opening 25 is provided on the outer wall of the inner core insertion area 21, and the lower edge of the inner core insertion opening 25 is close to the bottom of the cup body 2. The inner core 3 is pluggably arranged in the cup body 2 through the inner core insertion opening 25. A guide baffle 23 extending from the left and right sides of the inner core insertion opening 25 to the inside of the cup body is arranged inside the cup body 2. The guide baffle 23 extends along the radial direction of the cup body 2, and the bottom of the guide baffle 23 is connected to the bottom of the cup body 2; the length of the guide baffle 23 is less than the radius of the cup body 2 and is close to the insertion depth of the inner core 3; the height of the guide baffle 23 is less than the height of the inner core 3; there is a certain distance between the guide baffle 23 and the side wall of the inner core 3, so that the waste liquid flows from the side wall of the inner core 3 into the cup body 2. A bottom bracket 24 connected to the bottom edge of the inner core insertion opening 25 is also arranged inside the cup body 2. The bottom bracket 24 is arranged at the bottom of the cup body 2, and the bottom of the bottom bracket 24 is connected to the bottom of the cup body 2, which is used to support the inner core 3 from the bottom. The bottom bracket 24 is in a U-shape, and is used to support the edge of the bottom of the inner core 3, and forms a space for waste liquid to flow in the middle of the bottom bracket 24, so that the waste liquid can flow from the bottom of the inner core 3 into the cup body 2. The waste liquid can flow into the cup body 2 from the space between the bottom of the inner core 3 and the bottom of the cup body 2 and the gap between the side wall of the inner core 3 and the guide baffle 23, and be sucked out of the cup body 2 from the first channel 11 in the center of the cup body 2. Preferably, the guide baffle 23, the bottom bracket 24 and the entire shell of the cup body 2 are made of the same material.

[0046] The inner core fixing groove 26 is formed on the outer wall of the spacing area 22 . Two inner core fixing grooves 26 are provided between the two inner core insertion openings 25 . The inner core fixing groove 26 is used to cooperate with the elastic buckle 33 of the inner core 3 to fix the inner core 3 .

[0047] In addition, on the outer wall of the cup body 2, a serial number mark 28 is arranged above each inner core insertion opening 25, for marking the serial number of the corresponding inner core 3. In this embodiment, numbers 1, 2, 3, 4, 5, 6 are arranged above the six inner core insertion openings 25, respectively.

[0048] like Figure 8 and Fig. 9 As shown, the inner core 3 includes a collection box 30, a connecting plate 31, a handle 32 and an elastic buckle 33. Preferably, the collection box 30, the connecting plate 31, the handle 32 and the elastic buckle 33 are made of the same material. Among them, the side of the connecting plate 31 facing the center of the cup body is the inner side, the handle 31 is arranged on the outer side of the connecting plate 32, and the collection box 30 is arranged on the inner side of the connecting plate 32. The connecting plate 32 connecting the collection box 30 and the handle 31 is in an arc shape, and the connecting plate 32 fits the outer periphery of the above-mentioned cup body 2. Therefore, when multiple inner cores 3 are inserted into the cup body 2, the connecting plate 31 and the outer wall of the cup body 2 are arranged in a circular shape. The handle 31 facilitates the operation of plugging and unplugging the inner core 3, and its shape and material can be changed according to actual conditions.

[0049] The shape of the collection box 30 matches the shape of the area defined by the two guide baffles 23 and the bottom support 24 inside the inner core insertion port 25. The shape in this embodiment is a structure that gradually shrinks from the outside to the inside. The collection box 30 is a fan-shaped column with an upper opening when viewed from top to bottom. The fan-shaped column refers to a column shape with a fan-shaped cross section. Preferably, the cross section of the collection box 30 decreases from top to bottom, so that a gap for the flow of waste liquid is formed between the collection box 30 and the guide baffles 23. The collection box 30 in this embodiment has a fan-shaped bottom surface 301 and two rectangular side surfaces 302, and a plurality of filter holes 303 are respectively provided in the fan-shaped bottom surface 301 and the rectangular side surfaces 302 for the circulation of waste liquid. By providing filter holes 303 in the bottom surface 301 and the side surfaces 302 of the collection box 30, the flow rate of the waste liquid can be increased and the resistance to the flow of the waste liquid can be reduced. Of course, the filter holes 303 may be provided only in the sector-shaped bottom surface 301 or the rectangular side surface 302. Compared with providing the filter holes 303 on all three surfaces, this arrangement will result in greater resistance to the flow of waste liquid.

[0050] An elastic buckle 33 is provided on both sides of the collection box 30, and the elastic buckle 33 is connected to the inner side of the connection plate 32. The elastic buckle 33 includes a connection arm 331 and a hook portion 332 provided at the front end of the connection arm 331. The side of the hook portion 332 has two arc-shaped contact surfaces 333 and 334, and a tip 335 protruding away from the collection box 30 is formed at the intersection of the two contact surfaces, so as to facilitate the insertion and removal of the elastic buckle 33. Among them, the first contact surface 333 is closer to the connection plate 31 than the second contact surface 334.

[0051] When the inner core 3 is inserted inward, the elastic buckle 33 is inserted into the inner core fixing groove 26, the hook 332 contacts the edge of the inner core fixing groove 26, and the contact position moves from the first contact surface 333 to the tip 335. In the above process, the connecting arm 331 of the elastic buckle 33 is slightly deformed. When the contact position exceeds the tip 335, the connecting arm 331 returns to its original shape, and the hook 332 is stuck on the inner side of the inner wall of the cup body 2 to prevent the inner core 3 from moving.

[0052] When the inner core 3 is pulled outward, the contact position between the hook portion 332 and the inner core fixing groove 26 moves along the second contact surface 334. In the above process, the connecting arm 331 of the elastic buckle 33 is slightly deformed. When the contact position exceeds the tip 335, the hook portion 332 slides outward along the inner core insertion groove 26, thereby pulling out the inner core 3.

[0053] The tissue sample collection and separation device provided by the present invention is suitable for collecting and separating tissue samples in the process of obtaining human tissue samples through surgical resection. The tissue samples include tumors, diseased tissues and other control tissues (including near-cancerous tissues, adjacent tissues, normal tissues, etc.).

[0054] When the mixed liquid of the biopsy tissue sample and the waste liquid enters the inner core 3 through the liquid inlet channel (i.e., the second channel 12), the inner core 3 can separate the biopsy tissue sample and the waste liquid, thereby collecting the biopsy tissue sample in the collection box 30, and the waste liquid is automatically discharged, and the waste liquid is drawn out through the liquid outlet channel (i.e., the first channel 11); during the biopsy process, by rotating the cup cover 1, different tissue samples can be collected into different inner cores 3 to achieve separation requirements. Combined with the marks (e.g., 1, 2, 3, ...) set on the cup body 2, tissue samples of different biopsy positions can be obtained correspondingly, which is convenient for detection and analysis. The above-mentioned aspirator can be an endoscopic aspiration device, and the waste liquid sucked out by the suction pump flows into the waste liquid collection bottle.

[0055] In summary, the biopsy tissue sample collection and separation device provided by the present invention includes a cup body, a cup cover and a plurality of pluggable inner cores. By rotating the cup body, different inner cores are made to correspond to the liquid inlet channels, so that tissue samples from different parts can be collected in different inner cores, thereby realizing the corresponding collection of tissue samples from different parts; and the design of the pluggable inner core facilitates the removal and detection of tissue samples after collection, simplifies the operation, and is not prone to tissue sample contamination.

[0056] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A tissue sample collection and separation device, characterized in that It includes a cup body, a cup cover and multiple inner cores; wherein, A plurality of inner core insertion openings are provided on the outer circumference of the cup body, and the inner core is inserted into the interior of the cup body through the inner core insertion openings; The cup cover is covered on the cup body to seal the cup body, and the cup cover can rotate relative to the cup body in a state of covering the cup body; The cup cover is provided with a liquid inlet channel and a liquid outlet channel, wherein the liquid outlet channel is provided at the center of the cup cover, and the liquid inlet channel is provided at a position close to the edge of the cup cover; by rotating the cup body, the different inner cores are aligned with the liquid inlet channels, Wherein, the inner core comprises a connecting plate, a collecting box and a handle; the connecting plate is arc-shaped, the handle is arranged on the outside of the connecting plate, and the collecting box is arranged on the inside of the connecting plate; The collecting box comprises a sector-shaped bottom surface and two rectangular side surfaces, and a plurality of filtering holes are arranged in the sector-shaped bottom surface and / or the rectangular side surfaces; An elastic buckle is respectively provided on both sides of the collection box, and the elastic buckle is connected to the inner side of the connecting plate; on the cup body, an inner core fixing groove is respectively provided on both sides of each inner core insertion opening, for matching with the elastic buckle; The lower edge of the inner core insertion opening is close to the bottom of the cup body; the inner core is disposed close to the bottom of the cup body, and the height of the inner core exceeds 1 / 2 of the height of the cup body; The inner part of the cup body is a central area and a peripheral area for arranging the inner core, the peripheral area is divided into a plurality of inner core insertion areas for inserting the inner core and a plurality of spacing areas, the inner core insertion areas and the spacing areas are arranged alternately; A guide baffle is provided inside the cup body and extends radially from the left and right sides of the inner core insertion opening, respectively, and the bottom of the guide baffle is connected to the bottom of the cup body; a U-shaped bottom bracket connected to the bottom edge of the inner core insertion opening is also provided inside the cup body, and the bottom of the U-shaped bottom bracket is connected to the bottom of the cup body; The liquid inlet channel and the liquid outlet channel both penetrate the cup cover from top to bottom; one end of the liquid inlet channel extends into the cup body and extends to a position higher than the upper edge of the inner core insertion port, and the other end protrudes above the cup cover; one end of the liquid outlet channel extends into the cup body and extends to a position close to the bottom of the cup body, and the other end protrudes above the cup cover; A positioning portion is provided on the outer periphery of the cup cover, and the positioning portion is located on the same straight line as the liquid inlet channel and the liquid outlet channel. When the cup cover is rotated until the positioning portion is aligned with one of the inner cores, the second channel is located above the inner core and is used to guide waste liquid into the interior of the inner core.

2. The tissue sample collection and separation device according to claim 1, characterized in that: On the outer wall of the cup body, a serial number mark is arranged above each inner core insertion opening.

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