Intracranial parameter detection device

Abstract

The present invention provides an intracranial parameter detection device, including: a drainage tube body, a guide wire, a temperature-pressure detection device, and a biochemical parameter detection device, wherein the drainage tube body includes: a drainage cavity, the drainage cavity is provided with a drainage hole, so that after the drainage tube body is inserted into the cerebral ventricle, the cerebrospinal fluid flows into the drainage cavity through the drainage hole; a guide wire cavity, the guide wire cavity is arranged at the front end of the drainage tube body, and the guide wire is arranged in the guide wire cavity; a first detection cavity; a temperature-pressure detection device is arranged in the first detection cavity, and the temperature-pressure detection device is used to detect intracranial pressure ICP, cerebral perfusion pressure CPP, and intracranial temperature ICT; a biochemical parameter detection device is arranged in the drainage tube body, and the biochemical parameter detection device is used to detect the biochemical parameters of the cerebrospinal fluid drained into the drainage cavity. The device can realize cerebrospinal fluid drainage and realize real-time synchronous monitoring of multiple biochemical parameters of cerebrospinal fluid, intracranial pressure ICP, cerebral perfusion pressure CPP, and intracranial temperature ICT.

Description

Technical Field

[0001] The present invention relates to the technical field of medical equipment, and in particular to an intracranial parameter detection device. Background Art

[0002] The cerebrospinal fluid drainage tubes currently used in the market only have the function of monitoring intracranial pressure and intracranial temperature in addition to cerebrospinal fluid drainage. In addition, some companies have developed independent brain oximeters to measure blood oxygen parameters or independent brain microdialysis equipment to drain cerebrospinal fluid for monitoring biochemical indicators such as glucose, lactate, pyruvate, and glutamate. In other words, biochemical indicators can only be monitored after the cerebrospinal fluid is drained, and real-time synchronous monitoring of intracranial pressure, intracranial temperature, and biochemical parameters cannot be achieved while drainage is in progress.

[0003] Due to the mutual constraints between different intracranial indicators, a single evaluation cannot accurately assess the current microenvironment of the patient's brain. The above-mentioned indicator monitoring method may lead to inaccurate assessment of some patients, making it difficult to carry out individualized precision treatment, easily resulting in poor prognosis, and in severe cases, leading to the death of some patients. Summary of the invention

[0004] In order to solve the above technical problems, the present invention provides a drainage tube, which can realize cerebrospinal fluid drainage and realize real-time synchronous monitoring of multiple biochemical parameters of cerebrospinal fluid, intracranial pressure ICP (Intracranial Pressure), cerebral perfusion pressure CPP (Cerebral Perfusion Pressure), and intracranial temperature ICT (Intracranial Temperature), so that the condition can be evaluated more accurately and the purpose of individualized precision treatment can be achieved.

[0005] The invention also provides a medical device.

[0006] The technical solution adopted by the present invention is as follows:

[0007] The first aspect of the present invention proposes an intracranial parameter detection device, comprising: a drainage tube body, a guide wire, a temperature-pressure detection device, and a biochemical parameter detection device, wherein the drainage tube body comprises: a drainage cavity, the drainage cavity is provided with a drainage hole, so that after the drainage tube body is inserted into the cerebral ventricle, cerebrospinal fluid flows into the drainage cavity through the drainage hole; a guide wire cavity, the guide wire cavity is arranged at the front end of the drainage tube body, and a guide wire is arranged in the guide wire cavity; a first detection cavity; the temperature-pressure detection device is arranged in the first detection cavity, and the temperature-pressure detection device is used to detect intracranial pressure ICP, cerebral perfusion pressure CPP, and intracranial temperature ICT; the biochemical parameter detection device is arranged in the drainage tube body, and the biochemical parameter detection device is used to detect the biochemical parameters of cerebrospinal fluid drained into the drainage cavity.

[0008] The intracranial parameter detection device proposed in the present invention also has the following additional technical features:

[0009] According to one embodiment of the present invention, the intracranial parameter detection device includes a dual optical fiber, the dual optical fiber is arranged in the drainage cavity, and the dual optical fiber is used to collect near infrared information fNIRs of the liquid drained into the drainage cavity, and the fNIRs information includes: optical parameters (μ a , μ s ’ ) and SO2 (sulfur dioxide), Δ[Hb] (change in hemoglobin), Δ[HbO2] (change in oxygenated hemoglobin), and spectral characteristics.

[0010] According to one embodiment of the present invention, the temperature and pressure detection device includes: a thermistor; a pressure wafer, the pressure wafer is exposed to the outer wall of the drainage cavity through a first exposure window, and the first exposure window is exposed through a second exposure window arranged on the drainage tube body; a probe shell, the probe shell is arranged at the front end of the drainage tube body, and the probe shell wraps the thermistor and the pressure wafer; a first catheter, the first catheter is fixed by a colloid, and the first catheter is wrapped around the outside of a wiring harness connected to the thermistor and the pressure wafer.

[0011] According to one embodiment of the present invention, the biochemical parameter detection device includes: a plurality of micro-electrochemical sensors arranged in an array, each of the micro-electrochemical sensors correspondingly detecting a corresponding biochemical parameter; and a second catheter, the second catheter being used to wrap around the outside of a wiring harness connected to the micro-electrochemical sensor.

[0012] According to one embodiment of the present invention, the biochemical parameter detection device comprises: a plurality of needle-shaped biochemical indicator sensors, each of which is coated with a different reaction enzyme, and each reaction enzyme detects a corresponding biochemical parameter.

[0013] According to one embodiment of the present invention, the dual optical fiber includes: an incident optical fiber; an output optical fiber arranged corresponding to the incident optical fiber; and an insulating layer, wherein the insulating layer is wrapped around the outside of the incident optical fiber and the output optical fiber.

[0014] According to one embodiment of the present invention, the biochemical parameter detection device is disposed in the drainage cavity.

[0015] According to one embodiment of the present invention, the above-mentioned intracranial parameter detection device further includes: a second detection cavity, the second cavity is connected to the drainage cavity, and the biochemical parameter detection device is arranged in the second detection cavity.

[0016] According to one embodiment of the present invention, the biochemical parameters include one or more of the following parameters: oxygen partial pressure PO2, glucose Glc, lactate Lac, glutamate Glu, and pyruvate Pyr.

[0017] Beneficial effects of the invention:

[0018] The present invention can realize cerebrospinal fluid drainage and achieve real-time synchronous monitoring of multiple biochemical parameters of cerebrospinal fluid, intracranial pressure ICP, cerebral perfusion pressure CPP, and intracranial temperature ICT, so that the patient's condition can be evaluated more accurately and the purpose of individualized precision treatment can be achieved. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 is a CC cross-sectional view of an intracranial parameter detection device according to an embodiment of the present invention;

[0020] Figure 2 is a top view of an intracranial parameter detection device according to an embodiment of the present invention;

[0021] Figure 3 is a bottom view of an intracranial parameter detection device according to an embodiment of the present invention;

[0022] Figure 4 is a front view of an intracranial parameter detection device according to an embodiment of the present invention;

[0023] Figure 5 is a cross-sectional view of the AA line of the intracranial parameter detection device according to one embodiment of the present invention;

[0024] Figure 6 is a cross-sectional view of line BB of an intracranial parameter detection device according to an embodiment of the present invention;

[0025] Figure 7 is a schematic diagram of a right view, a front view, and a top view of a temperature and pressure detection device according to an embodiment of the present invention;

[0026] Figure 8 yes Figure 7 Sectional view along line AA;

[0027] Fig. 9 is a schematic diagram of a right view, a front view, and a top view of a biochemical parameter detection device according to an embodiment of the present invention;

[0028] Fig.10 is a schematic diagram of the arrangement of multiple micro electrochemical sensors according to one embodiment of the present invention;

[0029] Fig.11 is a schematic diagram of a front view of a biochemical parameter detection device according to another embodiment of the present invention;

[0030] Fig.12 yes Fig.11 A schematic diagram of a right view of the biochemical parameter detection device shown; Fig.13 is a schematic diagram of a right view, a front view, and a top view of a dual optical fiber according to an embodiment of the present invention;

[0031] Fig.14 is a cross-sectional view of a dual optical fiber according to an embodiment of the present invention;

[0032] Fig.15 It is a schematic diagram of a right view, a front view, and a top view of a guide wire according to an embodiment of the present invention. DETAILED DESCRIPTION

[0033] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0034] The present invention is made by the inventor based on the research and understanding of the following problems:

[0035] Clinical treatment plans and related treatment technologies for brain injury are also constantly improving, but the overall progress is slow, mainly because there are some bottleneck problems in monitoring technology that restrict the clinical treatment effect. When brain injury occurs, a series of dynamic changes occur in indicators such as intracranial fluid dynamics, photochemistry, electrochemistry and metabolism, and different indicators represent different aspects of clinical significance. At present, the occurrence and development of brain injury monitoring focuses on clinical indicators that can characterize brain injury, and has gradually formed relatively functionally independent monitoring technologies, including: intracranial pressure (ICP) (clinical gold standard), intracranial temperature (ICT), perfusion pressure (CPP), local brain tissue oxygen partial pressure (PO2), cerebral blood oxygen saturation (SO2), brain microdialysis (CMD, monitoring of biochemical indicators such as glucose, lactate, pyruvate, glutamate, etc.), transcranial Doppler ultrasound (TCD), near-infrared information (fNIRs), etc. Different indicators represent different clinical significance, but these indicators are not completely independent. The indicators influence and restrict each other. Relying on these independent indicators for clinical intervention is definitely not comprehensive.

[0036] In addition, intracranial pressure and intracranial temperature monitoring is achieved through invasive craniotomy, so there are relatively high requirements for the diameter of the ventricular drainage tube (<4mm). The shell end structure design of the probe of the multi-parameter real-time monitoring cerebrospinal fluid drainage tube is very difficult and difficult to develop. So far, there is no comprehensive multi-parameter real-time monitoring cerebrospinal fluid drainage tube for brain injury medical mechanism basis and clinical treatment application research at home and abroad.

[0037] The following is a description of the intracranial parameter detection device provided in an embodiment of the present invention in conjunction with the accompanying drawings.

[0038] like Figure 1-6 As shown, the intracranial parameter detection device includes: a drainage tube body 100, a guide wire 6, a temperature-pressure detection device 7, and a biochemical parameter detection device 4, wherein the drainage tube body 100 includes: a drainage cavity 1, a guide wire cavity 2 and a first detection cavity 3, the drainage cavity 1 is provided with a drainage hole 5, so that after the drainage tube body 100 is inserted into the ventricle, the cerebrospinal fluid flows into the drainage cavity 1 through the drainage hole 5; the guide wire cavity 2 is arranged at the front end of the drainage tube body 100, and the guide wire 6 is arranged in the guide wire cavity 2; the temperature-pressure detection device 7 is arranged in the first detection cavity 3, and the temperature-pressure detection device 7 is used to detect the intracranial pressure ICP, the cerebral perfusion pressure CPP, and the intracranial temperature ICT; the biochemical parameter detection device 4 is arranged in the drainage tube body 100, and the biochemical parameter detection device 4 is used to detect the biochemical parameters of the cerebrospinal fluid drained into the drainage cavity 1.

[0039] In a specific embodiment of the present invention, the biochemical parameters may include: oxygen partial pressure PO2, glucose Glc, lactic acid Lac, glutamate Glu, and pyruvic acid Pyr.

[0040] Specifically, the temperature-pressure detection device 7 is inserted into the first detection cavity 3, the guide wire 6 is inserted into the guide wire cavity 2, and the biochemical parameter detection device 4 is placed in the drainage cavity 1. The guide wire cavity 2 is set at the front end of the drainage tube for inserting the guide wire 6. The rigid structure (stainless steel) of the guide wire 6 can assist the doctor in inserting it into the cerebral ventricle during operation and pulling it out after the later operation.

[0041] In actual operation, medical personnel insert the probe-containing bougie into the ventricle, and then open the protective cover at the Luer interface of the cerebrospinal fluid drainage. The buried position of the bougie can be determined by the outflow of cerebrospinal fluid. The cerebrospinal fluid in the ventricle flows into the drainage cavity 1 through the drainage hole 5. The biochemical parameters of the drained cerebrospinal fluid can be detected by the biochemical parameter detection device 4 arranged on the inner side of the drainage tube body 100. At the same time, the intracranial pressure ICP, cerebral perfusion pressure CPP, and intracranial temperature ICT can be detected by the temperature-pressure detection device 7, so as to realize the real-time in vivo measurement of multiple index parameters, especially the real-time in vivo measurement of biochemical parameters, which replaces the results of the in vitro measurement of cerebrospinal fluid at the current stage, and accurately reflects the real-time indicators of the current patient.

[0042] Therefore, the drainage tube can achieve cerebrospinal fluid drainage and realize real-time synchronous monitoring of multiple biochemical parameters of cerebrospinal fluid, intracranial pressure ICP, cerebral perfusion pressure CPP, and intracranial temperature ICT, so that the patient's condition can be evaluated more accurately, achieving the purpose of individualized precision treatment, and making multi-parameter comprehensive evaluation and multimodal clinical research possible. In the later stage, a real-time evaluation physical model of typical brain injury can be established, realizing real-time, in-situ, objective, and continuous accurate evaluation of the degree of brain injury based on multimodal parameter monitoring.

[0043] As an example, the biochemical parameter detection device 4 can be directly arranged in the drainage cavity 1. During drainage, the biochemical parameter detection device 4 can directly contact the cerebrospinal fluid in the drainage cavity 1 to detect the biochemical parameters of the cerebrospinal fluid.

[0044] As another example, the drainage tube body 100 may further include: a second detection cavity, the second cavity is connected to the drainage cavity 1, and the biochemical parameter detection device 4 is disposed in the second detection cavity.

[0045] That is to say, a chamber (second detection chamber) can be set in the drainage tube body 100, and the second detection chamber needs to be connected with the drainage chamber 1. For example, the second detection chamber is set close to the drainage chamber 1, and the second detection chamber and the drainage chamber 1 are connected through corresponding holes, or the second detection chamber needs to be connected with the drainage chamber 1 through a catheter to drain part of the cerebrospinal fluid in the drainage chamber 1 to the second detection chamber, so that the biochemical parameter detection device set in the second detection chamber can contact the cerebrospinal fluid and realize the detection of biochemical parameters of the cerebrospinal fluid.

[0046] According to one embodiment of the present invention, Figure 1 As shown, the drainage tube may further include: dual optical fibers 8 , which are disposed in the drainage cavity 1 , and are used to collect near-infrared information fNIRs of the liquid drained into the drainage cavity 1 .

[0047] Specifically, the working principle of the dual optical fiber 8 is: the blood oxygen content in human tissue will change with the metabolic activity of the human body, and the change in blood oxygen content will cause the change in the optical properties of the tissue. The oxygenated hemoglobin and deoxygenated hemoglobin in the brain tissue have different characteristics for the near-infrared light absorption rate of 600-900nm wavelength. Therefore, near-infrared light can be used to irradiate the human tissue and detect the output light intensity. When the incident light intensity is known and the output light intensity can be measured, according to the Beer-Lambert law, the hemodynamic activity of the cerebral cortex can be detected in real time and directly. By observing this hemodynamic change, that is, through the law of neurovascular coupling, the neural activity of the brain can be inferred. fNIRs parameters can include: optical parameters (μ a , μ s’) and SO2 (sulfur dioxide), Δ[Hb] (change in hemoglobin), Δ[HbO2] (change in oxygenated hemoglobin), and spectral characteristics.

[0048] According to one embodiment of the present invention, Figure 7-8 As shown, the temperature and pressure detection device 7 may include: a thermistor 71, a probe shell 72, a pressure wafer 73 and a first conduit 74. The pressure wafer 73 is exposed to the outer wall of the drainage cavity through a first exposure window 75, and the first exposure window 75 is exposed through a second exposure window arranged on the drainage tube body 100; the probe shell 72 is arranged at the front end of the drainage tube body 100, and the probe shell 72 wraps the thermistor 71 and the pressure wafer 73; the first conduit 74 is fixed by a colloid 76, and the first conduit 74 is wrapped around the outside of the wiring harness connected to the thermistor and the pressure wafer.

[0049] Specifically, the first catheter 74 can wrap the relevant wiring harness to prevent the wiring harness from being exposed, thereby improving safety. The probe shell 72 senses the temperature and transmits it to the thermistor 71. The resistance of the thermistor 71 changes with the change in temperature. The relevant controller can obtain the corresponding temperature based on the thermistor 71, thereby obtaining the intracranial temperature ICT. The pressure wafer 73 senses the pressure change in the skull through the first exposure window and the second exposure window. The relevant controller can obtain the intracranial pressure ICP and the cerebral perfusion pressure CPP based on the pressure detected by the pressure wafer 73.

[0050] According to one embodiment of the present invention, Figure 9-10 As shown, the biochemical parameter detection device 4 may include: a plurality of micro electrochemical sensors 41 ( Figure 9-10 The plurality of micro-electrochemical sensors 41 are arranged in an array, and each micro-electrochemical sensor 41 detects a corresponding biochemical parameter; the second catheter 42 is used to wrap around the outside of the wiring harness connected to the micro-electrochemical sensor 41. Of course, the plurality of micro-electrochemical sensors 41 can also be arranged in a nonlinear manner, in a multi-cylindrical arrangement, etc., which can be set according to actual conditions.

[0051] Specifically, the second conduit 42 is used to wrap the relevant wire harness to prevent the wire harness from being exposed and improve safety. Figure 10-11 As shown, the micro electrochemical sensors 41 are arranged in an array or nonlinearly, and the micro electrochemical sensors 41 include but are not limited to one or more different physiological parameter measurement sensors such as glucose sensors, lactate sensors, glutamate sensors, glutamine sensors, pyruvic acid sensors, oxygen sensors, etc., and the order of positions is not limited. By using the biochemical parameter probe shell, specific biochemical indicators can be measured in situ in the body, accurately reflecting the real-time indicators of the current patient.

[0052] In addition to the biochemical parameter detection device 4 composed of the above-mentioned micro-electrochemical sensors, the biochemical parameter detection device can also be composed of needle-shaped biochemical indicator sensors.

[0053] Specifically, according to one embodiment of the present invention, Figure 11-12 As shown, the biochemical parameter detection device 4 may include: a plurality of needle-shaped biochemical indicator sensors 43, each needle-shaped biochemical indicator sensor 43 is coated with a different reaction enzyme, and each reaction enzyme detects a corresponding biochemical parameter.

[0054] Specifically, the front end of the probe of the biochemical parameter detection device 4 is composed of a needle-shaped biochemical indicator sensor, the reaction enzyme is coated on the needle, and the probe is inserted into the cerebrospinal fluid in the drainage cavity to measure the parameters. The sensor can be powered by electrodes, and there can be multiple electrodes 44, and the connection order can be freely combined, and there is one reference electrode 45.

[0055] According to one embodiment of the present invention, Figure 13-14 As shown, the dual optical fiber 8 may include: an incident optical fiber 81, an output optical fiber 82 and an insulating layer 83, wherein the output optical fiber 82 is arranged corresponding to the incident optical fiber; and the insulating layer 83 is wrapped around the outside of the incident optical fiber 81 and the output optical fiber 82.

[0056] Specifically, based on the known incident light intensity and the exiting light intensity of the incident optical fiber 81 and the exiting optical fiber 82, the hemodynamic activity of the cerebral cortex can be directly detected in real time using the Beer-Lambert law.

[0057] The structure of the guide wire 6 can be referred to Fig.15 shown.

[0058] In summary, according to the intracranial parameter detection device of the embodiment of the present invention, the biochemical parameters of the cerebrospinal fluid in the drainage cavity can be detected by a biochemical parameter detection device arranged on the inner side of the drainage cavity. At the same time, the intracranial pressure ICP, cerebral perfusion pressure CPP, and intracranial temperature ICT can be detected by a temperature-pressure detection device, so as to realize real-time in vivo measurement of multiple index parameters, especially real-time in vivo measurement of biochemical parameters, which can realize cerebrospinal fluid drainage and realize real-time synchronous monitoring of multiple biochemical parameters of cerebrospinal fluid, intracranial pressure ICP, cerebral perfusion pressure CPP, and intracranial temperature ICT, realize in vivo and in situ measurement of specific biochemical indicators, accurately reflect the real-time indicators of the current patient, enable the patient's condition to be more accurately evaluated, achieve the purpose of individualized and precise treatment, and make multi-parameter comprehensive evaluation and multi-modal clinical research possible. In the later stage, a real-time evaluation physical model of typical brain injury can be established to realize real-time, in situ, objective, and continuous precise evaluation of the degree of brain injury based on multi-modal parameter monitoring.

[0059] In the description of the present invention, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. "Multiple" means two or more, unless otherwise clearly and specifically defined.

[0060] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0061] In the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0062] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, unless they are contradictory.

[0063] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An intracranial parameter detection device, characterized in that: include: Drainage tube body, guide wire, temperature-pressure detection device, biochemical parameter detection device, wherein the drainage tube body includes: A drainage cavity, wherein the drainage cavity is provided with a drainage hole, so that after the drainage tube body is inserted into the cerebral ventricle, cerebrospinal fluid flows into the drainage cavity through the drainage hole; A guide wire cavity, which is arranged at the front end of the drainage tube body and has a guide wire arranged in it; A first detection chamber; The temperature-pressure detection device is arranged in the first detection cavity, and the temperature-pressure detection device is used to detect intracranial pressure ICP, cerebral perfusion pressure CPP, and intracranial temperature ICT; The biochemical parameter detection device is disposed in the drainage tube body, and the biochemical parameter detection device is used to detect the biochemical parameters of the cerebrospinal fluid drained into the drainage cavity; The temperature-pressure detection device comprises: Thermistor; a pressure wafer, wherein the pressure wafer is exposed to the outer wall of the drainage cavity through a first exposure window, and the first exposure window is exposed through a second exposure window provided on the drainage tube body; A probe shell, which is arranged at the front end of the drainage tube body and wraps the thermistor and the pressure wafer; A first conduit, the first conduit being fixed by a colloid, and the first conduit being wrapped around the outside of a wiring harness connected to the thermistor and the pressure wafer; The biochemical parameter detection device comprises: A plurality of micro-electrochemical sensors, wherein the plurality of micro-electrochemical sensors are arranged in an array, and each of the micro-electrochemical sensors detects a corresponding biochemical parameter; A second conduit is used to wrap around the outside of a wire harness connected to the micro electrochemical sensor.

2. The intracranial parameter detection device according to claim 1, characterized in that: Also includes: Dual optical fibers are arranged in the drainage cavity and are used to collect near-infrared information fNIRs of the liquid drained into the drainage cavity.

3. The intracranial parameter detection device according to claim 1, characterized in that: The biochemical parameter detection device comprises: A plurality of needle-shaped biochemical indicator sensors, each of which is coated with a different reaction enzyme, and each reaction enzyme detects a corresponding biochemical parameter.

4. The intracranial parameter detection device according to claim 2, characterized in that: The dual optical fibers include: Input fiber; An output optical fiber arranged corresponding to the input optical fiber; An insulating layer is wrapped around the input optical fiber and the output optical fiber.

5. The intracranial parameter detection device according to claim 1, characterized in that: The biochemical parameter detection device is arranged in the drainage cavity.

6. The intracranial parameter detection device according to claim 1, characterized in that: The drainage tube body further includes: a second detection cavity, the second detection cavity is connected to the drainage cavity, and the biochemical parameter detection device is arranged in the second detection cavity.

7. The intracranial parameter detection device according to any one of claims 1 to 6, characterized in that: The biochemical parameters include: oxygen partial pressure PO2, glucose Glc, lactic acid Lac, glutamic acid Glu, and pyruvic acid Pyr.

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