A blood sample automatic mixing device and mixing method

Abstract

A blood sample automatic mixing device, comprising a rotary motion mechanism, the rotary motion mechanism comprising a base and a rotary power source arranged on the base, characterized in that: the rotary motion mechanism also comprises a rotating seat, the bottom of the rotating seat is connected to the rotary power source, a guide groove is arranged in the rotating seat, at least one side of the guide groove is an inclined surface, which is used to form a caliber that is wide at the top and narrow at the bottom to tilt the lower part of the test tube, and also comprises a test tube holder arranged on one side of the rotating seat for limiting the upper part of the test tube. The rotating platform of the blood sample automatic mixing device is not prone to imbalance, has strong versatility, and has a good mixing effect. In addition, a mixing method of the blood sample automatic mixing device is provided.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a blood sample automatic mixing device and a mixing method. Background Art

[0002] The Chinese invention patent application with application publication number CN 105675376 A discloses a blood sample automatic mixing device, the structure of which is as follows: Figure 1 As shown, it includes a base 1a, a motor 2a, a gearbox 3a, a small bevel gear 4a, a rotating platform 5a, a connecting rod 6a, a large bevel gear 7a, a rotary encoder 8a, and a control device 9a; the front end of the base 1a is provided with a motor 2a, the output end of the motor 2a is connected to the input end of the gearbox 3a, the output shaft of the gearbox 3a is provided with a small bevel gear 4a, the small bevel gear 4a and the large bevel gear 7a are assembled together, the large bevel gear 7a is connected to the rotating platform 5a through a connecting rod 6a, the lower end of the connecting rod 6a is provided with a rotary encoder 8a, and the control device 9a is arranged at the rear end of the base 1a; the control device 9a is connected to the motor 2a and the gearbox 3a through a data line, the output end of the rotary encoder 8a is connected to the control device, an unbalance detection system is provided on the rotating platform and is electrically connected to the control device, and through holes of different calibers are also provided on the rotating platform 5a for vertically inserting test tubes of different calibers, and a sponge is provided in the through hole to protect the test tube. The blood sample automatic mixing device does not require manual operation, and can automatically shake the blood sample evenly just by starting the motor, with a high level of automation.

[0003] However, the existing automatic mixing device for blood samples still has the following technical problems: since the test tube is inserted into the through hole of the rotating platform 5a, in order to ensure that the test tube does not fall and is not easy to jump out during vibration, the large head of the test tube needs to be stuck in the through hole, so a longer connecting rod needs to be provided to ensure the insertion depth of the test tube. The longer connecting rod will cause imbalance when the rotating platform rotates. Therefore, it is necessary to add an imbalance detection system to the rotating platform and vertically insert the test tube into the through hole of the rotating platform 5a. Even if a variety of through holes with different calibers are provided, it can only meet the needs of a few specifications of test tubes, and the versatility is not strong. In addition, the mixing effect of the vertically inserted test tube is not good. Summary of the invention

[0004] The technical problem to be solved by the present invention is to provide a blood sample automatic mixing device with a rotating platform that is not prone to imbalance, strong versatility and good mixing effect.

[0005] The technical solution of the present invention is: a blood sample automatic mixing device, which includes a rotary motion mechanism, which includes a base and a rotary power source arranged on the base, and is characterized in that: the rotary motion mechanism also includes a rotating seat, the bottom of the rotating seat is connected to the rotary power source, a guide groove is provided in the rotating seat, at least one side of the guide groove is an inclined surface, which is used to form a caliber that is wide at the top and narrow at the bottom to tilt the lower part of the test tube, and also includes a test tube holder arranged on one side of the rotating seat for limiting the upper part of the test tube.

[0006] After adopting the above structure, the present invention has the following advantages:

[0007] The blood sample automatic mixing device of the present invention obliquely inserts the lower part of the test tube into the guide groove of the rotating seat, and then uses the test tube holder on one side of the rotating seat to prevent the test tube from jumping out when vibrating. The guide groove in the rotating seat and the test tube holder ensure the insertion depth of the test tube and prevent the test tube from jumping out. Therefore, it is only necessary to directly connect the bottom of the rotating seat with the rotating power source, so that the rotating seat is not prone to imbalance, and there is no need to set up an imbalance detection system; in addition, one side of the guide groove in the rotating seat is set as an inclined surface, which can make the test tube obliquely placed in the rotating seat, and the mixing effect is better than that of the test tube placed vertically. Moreover, the guide groove with the inclined surface is wide at the top and narrow at the bottom, and the wider upper caliber can meet the use requirements of test tubes of various calibers, and the versatility is also strong.

[0008] Preferably, one side of the guide groove is an inclined surface. Compared with the inclined surfaces on both sides, the inclined surface on one side has a relatively greater restraining force on the test tube, which can prevent the test tube from jumping out.

[0009] Preferably, an optical coupling sensor is provided on one side of the rotating seat on the base, an annular protrusion is provided on the outer side wall of the rotating seat, a positioning groove matching the annular protrusion is provided on the side of the optical coupling sensor close to the rotating seat, and a notch for triggering the optical coupling sensor is provided on the annular protrusion. The position of the rotating seat can be located by using the optical coupling sensor and the notch on the annular protrusion, so that the test tube in the rotating seat is in the same position after each mixing, which is convenient for automatic clamping by a mechanical arm, and is conducive to realizing the automation of the entire process. In addition, the cooperation between the annular protrusion and the positioning groove also makes the rotating seat rotate more smoothly.

[0010] As an advantage, the method further comprises a mechanical arm arranged near the test tube for holding the test tube, which makes the whole process more automated.

[0011] Preferably, the test tube holder comprises a frame connected to the base, and a sleeve arranged on the frame for clamping the upper part of the test tube. The frame is installed on the base, the structure is simpler, and the sleeve is used to limit the test tube, which has a simple structure and is more convenient to operate.

[0012] Preferably, the frame is provided with a height adjustment device, which can adapt to the requirements of test tubes of different lengths and has greater versatility.

[0013] Preferably, the frame includes an L-shaped bracket, the L-shaped bracket includes a horizontal plate for mounting a sleeve and a first vertical plate connected to the horizontal plate, the base is provided with a second vertical plate connected to the first vertical plate of the L-shaped bracket, the height adjustment device includes a vertical slide groove provided on one of the first vertical plate and the second vertical plate and an adjustment screw on the other vertical plate, the adjustment screw can slide up and down in the vertical slide groove and be locked in position. The frame has a simple structure, small overall space occupation, convenient height adjustment, and reliable height positioning.

[0014] Preferably, the sleeve is detachably connected to the frame, which can meet the use requirements of test tubes of various calibers by replacing different sleeves, and has greater versatility.

[0015] Another technical problem to be solved by the present invention is to provide a mixing method of an automatic blood sample mixing device with good mixing effect and high automation.

[0016] The technical solution of the present invention is: a mixing method of a blood sample automatic mixing device, characterized in that it comprises the following steps:

[0017] (1) The test tube is automatically clamped by a robotic arm and passed through the sleeve on the test tube holder and placed obliquely in the guide groove of the rotating seat;

[0018] (2) starting the rotary power source on the base, which drives the rotating seat to rotate, and the lower half of the test tube obliquely placed in the rotating seat rotates, so that the peripheral blood in the test tube is mixed;

[0019] (3) The optical coupling sensor detects the position of the notch of the annular protrusion on the rotating seat in real time. The optical coupling sensor is triggered once each time the notch passes by. When the triggering times reach the set times, the rotating power source on the control base stops;

[0020] (4) The test tube on the rotating seat is automatically removed by a robotic arm.

[0021] After adopting the above method, the present invention has the following advantages:

[0022] The mixing method of the automatic blood sample mixing device of the present invention places the test tube obliquely in the rotating seat, which has a better mixing effect than the test tube placed vertically. The position of the rotating seat can be located by using the optical coupling sensor and the notch on the annular protrusion. In this way, the test tube in the rotating seat is in the same position after each mixing, which is convenient for automatic clamping using a robotic arm, and the degree of automation is high. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is a structural schematic diagram of an existing blood sample automatic mixing device;

[0024] Figure 2 It is a schematic diagram of the three-dimensional structure of the automatic mixing device for blood samples in Example 1;

[0025] Figure 3 It is a side view of the blood sample automatic mixing device in Example 1;

[0026] Figure 4 A half-section diagram of the automatic blood sample mixing device in Example 1;

[0027] Figure 5 It is a schematic diagram of the structure of the rotating base of the blood sample automatic mixing device in Example 1;

[0028] Figure 6 It is a front view of the blood sample automatic mixing device in Example 2;

[0029] In the prior art figure: 1a-base, 2a-motor, 3a-gearbox, 4a-small bevel gear, 5a-rotating platform, 6a-connecting rod, 7a-large bevel gear, 8a-rotary encoder, 9a-control device;

[0030] In the figure of the present invention: 1-base, 2-rotational power source, 3-rotational seat, 4-guide groove, 5-inclined surface, 6-test tube holder, 7-optical coupling sensor, 8-annular protrusion, 9-positioning groove, 10-notch, 11-frame, 12-sleeve, 13-height adjustment device, 14-L-shaped bracket, 15-horizontal plate, 16-first vertical plate, 17-second vertical plate, 18-vertical slide groove, 19-adjusting screw, 20-mechanical arm. DETAILED DESCRIPTION

[0031] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0032] Embodiment 1:

[0033] A blood sample automatic mixing device, comprising a rotary motion mechanism, the rotary motion mechanism comprising a base 1 and a rotary power source 2 arranged on the base 1, the rotary motion mechanism also comprising a rotating seat 3, the bottom of the rotating seat 3 is connected to the rotary power source 2, the rotary power source 2 can be various types of motors or other power. In this embodiment, the rotary power source 2 is a DC brushless reduction motor, a guide groove 4 is provided in the rotating seat 3, at least one side of the guide groove 4 is an inclined surface 5, which is used to form a caliber that is wide at the top and narrow at the bottom to tilt the lower part of the test tube, and also includes a test tube holder 6 arranged on one side of the rotating seat 3 for limiting the upper part of the test tube.

[0034] The blood sample automatic mixing device of the present invention inserts the lower part of the test tube obliquely into the guide groove 4 of the rotating seat 3, and then uses the test tube holder 6 on one side of the rotating seat 3 to prevent the test tube from jumping out when vibrating. The guide groove 4 in the rotating seat 3 and the test tube holder 6 ensure the insertion depth of the test tube and prevent the test tube from jumping out. Therefore, it is only necessary to directly connect the bottom of the rotating seat 3 with the rotating power source 2, so that the rotating seat 3 is not prone to imbalance, and there is no need to set up an imbalance detection system; in addition, one side of the guide groove 4 in the rotating seat 3 is set as an inclined surface 5, which can make the test tube obliquely placed in the rotating seat 3, and the mixing effect is better than that of the test tube placed vertically, and the guide groove 4 with the inclined surface 5 is wide at the top and narrow at the bottom, and the wider upper caliber can meet the use requirements of test tubes of various calibers, and the versatility is also strong.

[0035] Preferably, one side of the guide groove 4 is an inclined surface 5. Arranging the inclined surface 5 on one side has a relatively greater restraining force on the test tube than arranging the inclined surfaces 5 on both sides, thereby preventing the test tube from jumping out.

[0036] Preferably, the base 1 is provided with an optical coupling sensor 7 on one side of the rotating seat 3, an annular protrusion 8 is provided on the outer wall of the rotating seat 3, a positioning groove 9 matching the annular protrusion 8 is provided on the side of the optical coupling sensor 7 close to the rotating seat 3, and a notch 10 for triggering the optical coupling sensor 7 is also provided on the annular protrusion 8, and the optical coupling sensor 7 can be made of existing technology. The position of the rotating seat 3 can be located by using the optical coupling sensor 7 and the notch 10 on the annular protrusion 8, so that the test tubes in the rotating seat 3 are in the same position after each mixing, which is convenient for automatic clamping by the mechanical arm 20, and is conducive to realizing the automation of the entire process. In addition, the cooperation between the annular protrusion 8 and the positioning groove 9 also makes the rotating seat 3 rotate more smoothly.

[0037] Preferably, the test tube holder 6 comprises a frame body 11 connected to the base 1, and a sleeve 12 arranged on the frame body 11 for clamping the upper part of the test tube. The frame body 11 is installed on the base 1, the structure is simpler, and the sleeve 12 is used to limit the test tube, which has a simple structure and is more convenient to operate.

[0038] Preferably, the frame 11 is provided with a height adjustment device 13. This arrangement can adapt to the requirements of test tubes of different lengths and has greater versatility.

[0039] Preferably, the frame 11 includes an L-shaped bracket 14, the L-shaped bracket 14 includes a horizontal plate 15 for installing the sleeve 12 and a first vertical plate 16 connected to the horizontal plate 15, the base 1 is provided with a second vertical plate 17 connected to the first vertical plate 16 of the L-shaped bracket 14, the height adjustment device 13 includes a vertical slide 18 provided on one of the first vertical plate 16 and the second vertical plate 17 and an adjustment screw 19 on the other vertical plate, the adjustment screw 19 can slide up and down in the vertical slide 18 and lock and position. The frame 11 has a simple structure, small overall space occupation, convenient height adjustment, and reliable height positioning.

[0040] Preferably, the sleeve 12 is detachably connected to the frame 11. This arrangement can meet the use requirements of test tubes of various calibers by replacing different sleeves 12, and has stronger versatility.

[0041] Embodiment 2:

[0042] This embodiment is based on the embodiment 1 and has the following additional structures: it also includes a mechanical arm 20 for clamping the test tube, which is arranged near the test tube. In this embodiment, the mechanical arm 20 is arranged above the sleeve 12 and the mechanical arm 20 can be made of existing technology. The mechanical arm 20 makes the whole process more automated.

[0043] Embodiment 3:

[0044] A mixing method of an automatic blood sample mixing device, the method is based on the automatic blood sample mixing device described in Example 2, and the method comprises the following steps:

[0045] (1) The test tube is automatically clamped by the robot arm 20, passed through the sleeve 12 on the test tube holder 6, and is obliquely placed in the guide groove 4 of the rotating seat 3;

[0046] (2) starting the rotary power source 2 on the base 1, the rotary power source 2 drives the rotating base 3 to rotate, and the lower half of the test tube obliquely placed in the rotating base 3 performs a rotating motion, so that the peripheral blood in the test tube is mixed;

[0047] (3) The optical coupling sensor 7 detects the position of the notch 10 of the annular protrusion 8 on the rotating seat 3 in real time. The optical coupling sensor 7 is triggered once each time the notch 10 passes by. When the triggering times reach the set times, the rotating power source 2 on the control base 1 stops;

[0048] (4) The test tube on the rotating seat 3 is automatically taken out by the robot arm 20.

[0049] The mixing method of the blood sample automatic mixing device of the present invention places the test tube obliquely in the rotating seat 3, which has a better mixing effect than the test tube placed vertically. The position of the rotating seat 3 can be located by using the optical coupling sensor 7 and the notch 10 on the annular protrusion 8. In this way, the test tube in the rotating seat 3 is in the same position after each mixing, which is convenient for automatic clamping by the mechanical arm 20, and the degree of automation is high.

Claims

1. A blood sample automatic mixing device, comprising a rotary motion mechanism, wherein the rotary motion mechanism comprises a base (1) and a rotary power source (2) arranged on the base (1), characterized in that: The rotary motion mechanism further comprises a rotary seat (3), the bottom of which is connected to a rotary power source (2), a guide groove (4) being arranged in the rotary seat (3), one side of which is an inclined surface (5) for forming an aperture which is wide at the top and narrow at the bottom so as to obliquely place the lower part of a test tube, and a test tube holder (6) arranged on one side of the rotary seat (3) for limiting the upper part of the test tube, an optical coupling sensor (7) being arranged on the side of the rotary seat (3) on the base (1), an annular protrusion (8) being arranged on the outer side wall of the rotary seat (3), a positioning groove (9) cooperating with the annular protrusion (8) being arranged on the side of the optical coupling sensor (7) close to the rotary seat (3), a notch (10) for triggering the optical coupling sensor (7) being arranged on the annular protrusion (8), and the test tube holder (6) comprising a frame body (11) connected to the base (1), and a sleeve (12) arranged on the frame body (11) for clamping the upper part of the test tube.

2. The blood sample automatic mixing device according to claim 1, characterized in that: It also includes a mechanical arm (20) arranged near the test tube and used for clamping the test tube.

3. The blood sample automatic mixing device according to claim 1, characterized in that: The frame (11) is provided with a height adjustment device (13).

4. The blood sample automatic mixing device according to claim 3, characterized in that: The frame (11) comprises an L-shaped bracket (14), wherein the L-shaped bracket (14) comprises a horizontal plate (15) for mounting a sleeve (12) and a first vertical plate (16) connected to the horizontal plate (15); the base (1) is provided with a second vertical plate (17) connected to the first vertical plate (16) of the L-shaped bracket (14); the height adjustment device (13) comprises a vertical slide groove (18) arranged on one of the first vertical plate (16) and the second vertical plate (17) and an adjustment screw (19) on the other vertical plate; the adjustment screw (19) can slide up and down in the vertical slide groove (18) and be locked in place.

5. The blood sample automatic mixing device according to claim 1, characterized in that: The sleeve (12) is detachably connected to the frame (11).

6. A mixing method of an automatic blood sample mixing device, the mixing method is based on the automatic blood sample mixing device according to any one of claims 1 to 5, characterized in that: It includes the following steps: (1) A test tube is automatically gripped by a mechanical arm (20), passed through a sleeve (12) on a test tube holder (6), and obliquely placed in a guide groove (4) of a rotating seat (3); (2) starting the rotating power source (2) on the base (1), the rotating power source (2) drives the rotating base (3) to rotate, The lower part of the test tube obliquely placed in the rotating seat (3) performs a rotating motion to mix the peripheral blood in the test tube; (3) The optical coupling sensor (7) detects the position of the notch (10) of the annular protrusion (8) on the rotating seat (3) in real time. The optical coupling sensor (7) is triggered once each time the notch (10) passes by. When the number of triggering times reaches the set number, Controlling the rotation power source (2) on the base (1) to stop; (4) The test tube on the rotating seat (3) is automatically taken out by the robot arm (20).

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