Device for controlling the sequential mixing reaction of reagents by centrifugal force

The reaction tube is driven to rotate through the centrifugal device, and the reagents are mixed in sequence by centrifugal force, which solves the problems of low efficiency and splashing in manual shake, and realizes full mixing and automated reaction of chemical reagents.

CN114053987BActive Publication Date: 2024-12-10HANGZHOU VOCATIONAL & TECHN COLLEGE
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Patent Information

Application Number
CN202111500277.7
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2021-12-09
Publication Date
2024-12-10
Estimated Expiration
2041-12-09

AI Technical Summary

Technical Problem

The existing chemical reagents need to be shaken manually during the reaction process, which is inefficient and can easily cause reagent splashing, and cannot achieve automated mixing reactions.

Method used

A device is designed to drive the reaction tube rotation through a centrifugal device and control the sequential mixing of reagents using centrifugal force, including a slanted reaction tube placement groove and a fixing belt buckle to ensure that the reagent is fully mixed and prevent splashing.

Benefits of technology

Full mixing and sequential reaction of chemical reagents is achieved, reaction efficiency is improved, and simultaneous comparison tests of multiple reaction tubes are supported.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention relates to a device for controlling the sequential mixing reaction of reagents through centrifugal force. A reaction tube is fixed in a reaction tube placement groove through a reaction tube fixing buckle, and the reaction tube is driven to perform circular motion through a centrifugal rotating shaft, so that the chemical reagents in the reaction tube are fully integrated, ensuring that the chemical reagent mixing reaction is fully carried out. At the same time, the reaction tube placement groove arranged obliquely can adjust the flow direction of the reagents in the reaction tube, thereby ensuring that the reagents in the reaction tube are mixed and reacted in sequence; and a plurality of reaction tube placement grooves are arranged in a centrifugal support at the same time, so that the device can perform comparative tests on the chemical reagents in a plurality of reaction tubes at the same time.
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Description

Technical Field

[0001] The invention relates to the field of chemical experimental equipment, in particular to a device for controlling the sequential mixing reaction of reagents through centrifugal force. Background Art

[0002] Reagents, also known as biochemical reagents or test drugs, are mainly pure chemicals used to achieve chemical reactions, analytical tests, research experiments, teaching experiments, and chemical formulas. They are generally divided into general reagents, high-purity reagents, analytical reagents, instrumental analytical reagents, clinical diagnostic reagents, biochemical reagents, inorganic ion colorimetric reagents, etc.

[0003] In the prior art, the preparation and reaction process of chemical reagents requires that the chemicals in the reaction tube be shaken to allow different chemicals to be fully mixed and reacted. However, manual shaking takes a long time and is prone to splashing of reaction reagents during the shaking process. Manual shaking can only shake one container at a time. Manual shaking will cause problems such as insufficient and low efficiency of shaking, and is not conducive to realizing the automation of solution mixing reactions. Summary of the invention

[0004] In order to solve the above problems, the present invention provides a device that drives the rotation of a reaction tube through a centrifugal device, thereby shaking the chemical reagents in the reaction tube, making the chemical reagents in the reaction tube fully integrated, and ensuring that the reagents in the reaction tube are mixed and reacted in sequence, and controlling the sequential mixing reaction of the reagents through centrifugal force.

[0005] In order to achieve the above-mentioned purpose, the device designed by the present invention controls the sequential mixing reaction of reagents by centrifugal force, mainly comprising a centrifugal support, a centrifugal shaft is fixedly arranged in the middle of the centrifugal support, and a plurality of reaction tube placement grooves arranged obliquely are opened on the inner side of the centrifugal support, and the plurality of reaction tube placement grooves are uniformly distributed around the centrifugal shaft, and the distance from the notch of the reaction tube placement groove to the centrifugal shaft is greater than the distance from the bottom of the reaction tube placement groove to the centrifugal shaft. The setting of this structure controls the flow direction of the reagents in the reaction tube during the reaction process through the oblique reaction tube placement grooves, thereby ensuring that the reagents in the reaction tube are mixed and reacted in sequence.

[0006] A further solution is that the centrifugal support is provided with a reaction tube fixing buckle for preventing the reaction tube in the reaction tube placement slot from being thrown out due to centrifugal force. This structure is arranged to fix the reaction tube in the reaction tube placement slot by the arrangement of the reaction tube fixing buckle.

[0007] A further solution is that an L-shaped connecting arm is provided at one end of the reaction tube fixing buckle, the L-shaped connecting arm cooperates and fixes with the reaction tube placed in the reaction tube placement groove, and a J-shaped undercut is provided at the other end of the reaction tube fixing buckle to cooperate and fasten with the centrifugal support. This structure is set up to seal the tube opening of the reaction tube through the L-shaped connecting arm in the reaction tube fixing buckle, and further fix the reaction tube in the reaction tube placement groove through the J-shaped undercut, thereby preventing the reaction tube from flying out of the reaction tube placement groove during the reagent reaction process.

[0008] A further solution is that the centrifugal support is connected to the L-shaped connecting arm via a hinge. The arrangement of this structure controls the switch of the reaction tube fixing buckle through the arrangement of the hinge.

[0009] The device designed by the present invention controls the sequential mixing reaction of reagents by centrifugal force, fixes the reaction tube in the reaction tube placement groove by a reaction tube fixing buckle, and drives the reaction tube to perform circular motion by a centrifugal rotating shaft, so that the chemical reagents in the reaction tube are fully integrated, ensuring that the chemical reagent mixing reaction is fully carried out, and at the same time, the reaction tube placement groove arranged obliquely can adjust the flow direction of the reagents in the reaction tube, thereby ensuring that the reagents in the reaction tube are mixed and reacted in sequence; and multiple reaction tube placement grooves are simultaneously arranged in the centrifugal support, so that the device can perform comparative tests on the chemical reagents in multiple reaction tubes at the same time. BRIEF DESCRIPTION OF THE DRAWINGS

[0010] Figure 1 An axonometric view of a device for controlling the sequential mixing reaction of reagents by centrifugal force.

[0011] Figure 2 It is a cross-sectional view of a device for controlling the sequential mixing reaction of reagents by centrifugal force.

[0012] Figure 3 It is a schematic diagram of the operation process of a device for controlling the sequential mixing reaction of reagents by centrifugal force. DETAILED DESCRIPTION

[0013] In order to further explain the technical means and effects adopted by the present invention to achieve the predetermined invention purpose, the specific implementation mode, structure, characteristics and effects of the present invention are described in detail below in combination with the accompanying drawings and preferred embodiments.

[0014] Example 1.

[0015] like Figure 1 and Figure 2As shown, the device described in this embodiment controls the sequential mixing reaction of reagents by centrifugal force, mainly comprising a centrifuge support 1, a centrifuge shaft 2 is fixedly provided in the middle of the centrifuge support 1, four obliquely arranged reaction tube placement grooves 3 are evenly distributed on the inner circumference of the centrifuge support 1, and the distance from the groove opening of the reaction tube placement groove 3 to the centrifuge shaft 2 is greater than the distance from the bottom of the reaction tube placement groove 3 to the centrifuge shaft 2, and a reaction tube 4 is fixedly arranged in the reaction tube placement groove 3.

[0016] The centrifugal support 1 is hingedly connected to a reaction tube fixing buckle 5 , one end of which is provided with an L-shaped connecting arm 6 for closing the tube opening of the reaction tube 4 , and the other end is provided with a J-shaped undercut 7 for fastening with the centrifugal support 1 .

[0017] The working process of the device for controlling the sequential mixing reaction of reagents by centrifugal force is as follows:

[0018] First, a reaction tube containing a sample reagent 8 and a reaction reagent 9 is placed in an obliquely arranged reaction tube placement slot 3 in a centrifugal support 1, and the plane where the reaction reagent 9 in the reaction tube is located is higher than the plane where the sample reagent 8 is located;

[0019] The L-shaped connecting arm 6 in the reaction tube fixing buckle 5 is matched and fixed with the tube mouth of the reaction tube 4, and the J-shaped undercut 7 is matched and fixed with the side wall of the centrifugal support 1;

[0020] The rotation of the centrifugal shaft 2 drives the reaction tube 4 in the reaction tube placement tank 3 to perform non-uniform circular motion, and the reaction tube 4 in the reaction tube placement tank 3 is obtained. Figure 2 ;

[0021] By increasing the rotation rate of the reaction tube 4, the sample reagent 8 in the reaction tube 4 flows toward the reaction reagent 9, and the Figure 3 ;

[0022] The sample reagent 8 and the reaction reagent 9 in the reaction tube 4 are fully integrated, and the mixing reaction of the sample reagent 8 and the reaction reagent 9 is ensured to be fully carried out.

[0023] The above description is only a preferred embodiment of the present invention and does not limit the present invention in any form. Although the present invention has been disclosed as a preferred embodiment as above, it is not used to limit the present invention. Any technical personnel in this field can make some changes or modify the technical contents disclosed above into equivalent embodiments without departing from the scope of the technical solution of the present invention. However, any brief modifications, equivalent changes and modifications made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention are still within the scope of the technical solution of the present invention.

Claims

1. A device for controlling the sequential mixing reaction of reagents by centrifugal force, mainly comprising a centrifugal support (1), a centrifugal shaft (2) is fixedly arranged in the middle of the centrifugal support (1), characterized in that The centrifuge support (1) is provided with a plurality of reaction tube placement grooves (3) arranged obliquely on the inner side. The plurality of reaction tube placement grooves (3) are evenly distributed around the centrifuge shaft (2), and the distance from the groove opening of the reaction tube placement groove (3) to the centrifuge shaft (2) is greater than the distance from the groove bottom of the reaction tube placement groove (3) to the centrifuge shaft (2); the centrifuge support (1) is provided with a reaction tube fixing buckle (5) for limiting the reaction tube (4) in the reaction tube placement groove (3) from being thrown out due to centrifugal force, and the inner wall of the reaction tube (4) is provided with two reagent chambers of different heights.

2. The device for controlling the sequential mixing reaction of reagents by centrifugal force according to claim 1, characterized in that An L-shaped connecting arm (6) is arranged at one end of the reaction tube fixing buckle (5), and the L-shaped connecting arm (6) cooperates and fixes with the reaction tube (4) placed in the reaction tube placement groove (3); and a J-shaped undercut (7) is arranged at the other end of the reaction tube fixing buckle (5) and cooperates and fastens with the centrifugal support (1).

3. The device for controlling the sequential mixing reaction of reagents by centrifugal force according to claim 2, characterized in that The centrifugal support (1) and the L-shaped connecting arm (6) are connected via a hinge.