A cell separation and extraction device for children's blood disease testing
By designing a cell separation and extraction device for the examination of children's blood diseases, the problem of slow progress in manual extraction of blood cells in the prior art is solved, and the automation of blood centrifugation and cell extraction is realized, which improves work efficiency and reduces the test time.
Patent Information
- Application Number
- CN202111502259.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2021-12-10
- Publication Date
- 2025-03-07
- Estimated Expiration
- 2041-12-10
AI Technical Summary
In the prior art, in the test of blood diseases in children, manual blood cells extraction progresses slowly, resulting in a longer test time.
A cell separation and extraction device for the examination of children's blood diseases was designed, including a test table, centrifugal block, blood centrifugal tank, rotating cover plate, rubber airbag and liquid extraction tube. Driven by electric telescopic rod and motor, the automation of blood centrifugal and cell extraction is achieved.
The device can quickly and automatically perform blood centrifugation and cell extraction, significantly improve work efficiency, reduce manpower and test time, and is suitable for processing multiple children's blood samples at the same time.
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Figure CN114214180B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of blood disease testing, and in particular to a cell separation and extraction device for testing blood diseases in children. Background Art
[0002] Hematopoietic system diseases are commonly known as blood diseases. They are diseases that originate in the hematopoietic system and mainly affect the hematopoietic system. The symptoms and signs of blood diseases vary, and the most common ones are: anemia, bleeding, fever, lymph node, liver, and spleen enlargement. There are many causes of blood diseases, including: chemical factors, physical factors, biological factors, genetic factors, immune factors, etc. The earlier the blood disease is discovered, the earlier it can be cured, and thus the detection and treatment of blood diseases in children is particularly important.
[0003] In the examination of children's blood diseases, it is necessary to perform cell extraction on the collected children's blood. In the prior art, the test tube containing the children's blood is usually centrifuged first, and then the red blood cells or plasma are manually extracted using a dropper after it is allowed to stand and stratify. Since the number of tests is usually large, the manual extraction work progresses slowly, resulting in a long test time.
[0004] To solve the above problems, we proposed a cell separation and extraction device for children's blood disease testing. Summary of the invention
[0005] The purpose of the present invention is to solve the problems in the background technology and to propose a cell separation and extraction device for children's blood disease testing.
[0006] In order to achieve the above-mentioned purpose, the present invention adopts the following technical scheme: a cell separation and extraction device for testing children's blood diseases, comprising a test table, wherein the lower end of the test table is fixedly connected to four supporting legs distributed in a rectangular shape, the upper end of the test table is rotatably connected to a rotating disk, a first electric telescopic rod is fixedly installed at the center position of the upper end of the rotating disk, the telescopic end of the first electric telescopic rod is fixedly connected to a rotating plate, a circular centrifugal opening is opened on the test table and at the right side of the first electric telescopic rod, a centrifugal block is rotatably connected on the inner peripheral wall of the centrifugal opening, a plurality of groups of blood centrifugal grooves are opened on the circumferential direction of the centrifugal block, a rotating groove is opened at the center position of the upper end of the centrifugal block, a driving frame with an inner wall of a regular hexagon is rotatably connected to the upper end of the test table and at the outer side of the centrifugal opening, the outer peripheral wall of the driving frame is circular and fixedly sleeved with a gear ring;
[0007] An extraction mechanism is provided at the lower end of the rotating plate and at a corresponding position above the centrifugal port, the extraction mechanism comprises a fixed rod fixedly connected to the lower end of the rotating plate and arranged concentrically with the centrifugal block, the lower end of the fixed rod is rotatably connected to a rotating cover plate with the same shape as the inner wall of the driving frame, the center position of the lower end of the rotating cover plate is fixedly connected to a rotating block, a movable sleeve block is slidably sleeved on the fixed rod, a rotating sleeve plate is rotatably sleeved on the movable sleeve block, a rubber airbag is fixedly connected to the upper end of the rotating sleeve plate and at the corresponding position of each blood centrifugal tank, the lower end of each rubber airbag is connected to a liquid extraction tube, and the lower end of the liquid extraction tube passes through the rotating cover plate;
[0008] The upper end of the rotating sleeve plate is evenly and fixedly connected with four vertical rods, and the upper end of each of the vertical rods is commonly and fixedly connected with an annular plate, which is sleeved on the fixed rod, and the upper end of the annular plate is provided with an annular groove with a T-shaped cross section, and a slider is slidably connected in the annular groove, and a second electric telescopic rod is fixedly installed on the rotating plate, and the telescopic end of the second electric telescopic rod extends into the annular groove and is fixedly connected to the upper end of the slider;
[0009] An annular baffle is fixedly connected to the upper end of the rotating sleeve and at the outer and inner positions of the rubber airbag. Each of the rubber airbags is located between the two annular baffles. An annular pressing plate is slidably connected to the opposite sides of the two annular baffles. The pressing plate is fixedly connected to the upper end of each rubber airbag. Limiting grooves are provided at both ends of the pressing plate. Limiting rods are horizontally inserted at the corresponding positions of the annular baffle located on the outer side and below the limiting grooves. An end block is fixedly connected to the end of the limiting rod away from the annular baffle. A spring is fixedly connected between the end block and the annular baffle, and the spring is sleeved on the corresponding limiting rod.
[0010] In the above-mentioned cell separation and extraction device for testing blood diseases in children, a first motor for driving the rotating disk to rotate is fixedly installed at the lower end of the testing table.
[0011] In the above-mentioned cell separation and extraction device for testing children's blood diseases, a second motor is fixedly embedded on the upper end of the testing table, and a gear is fixedly sleeved on the output end of the second motor, and the gear is meshed with a gear ring.
[0012] In the above-mentioned cell separation and extraction device for testing children's blood diseases, a collection plate is provided at the upper end of the testing table and at the left side of the first electric telescopic rod.
[0013] In the above-mentioned cell separation and extraction device for testing children's blood diseases, the positions of the rotating block and the rotating groove correspond to each other and both are regular hexagonal structures.
[0014] In the above-mentioned cell separation and extraction device for testing children's blood diseases, the lower end of the rotating cover and the corresponding positions of each liquid extraction tube are fixedly connected with sealing blocks, and the sealing blocks are sleeved on the corresponding liquid extraction tubes.
[0015] Compared with the existing technology, the advantages of this cell separation and extraction device for children's blood disease testing are:
[0016] After the children's blood is placed in each blood centrifugal tank, it is only necessary to press the pressing plate in advance and use the limiting plug rod to position it so that the rubber airbag remains in a compressed state, and then the rotating cover plate is driven by the first electric telescopic rod to move down and cover the centrifugal block. The rotating cover plate and the driving frame are both regular hexagonal structures, so that the second motor can directly drive the centrifugal block and the rotating cover plate to rotate synchronously, so that the children's blood is centrifuged in the blood centrifugal tank. After the centrifugation is completed, the blood is statically layered. At this time, it is only necessary to control the up and down movement of the rotating sleeve plate by the second electric telescopic rod to move each liquid extraction tube downward and insert it into the layered children's blood. After moving down to a suitable length as needed, the limiting plug rod is pulled out to move the pressing plate upward, the rubber airbag is restored, and suction is generated to suck the corresponding blood cells into the liquid extraction tube. Then, it is only necessary to control the lifting and rotation of the first electric telescopic rod to extract the absorbed blood cells into the collection plate. Compared with the previous children's blood cell separation and extraction work, the efficiency is higher, multiple children's blood can be separated at the same time, and the extraction of each blood cell can be carried out quickly, which saves manpower and reduces the inspection time. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 This is a structural perspective view of the front side of a cell separation and extraction device for testing children's blood diseases proposed by the present invention;
[0018] Figure 2 A partial structural perspective view of the front side of an extraction mechanism in a cell separation and extraction device for testing blood diseases in children proposed by the present invention;
[0019] Figure 3 for Figure 2 The enlarged structural diagram at A in the middle;
[0020] Figure 4 This is a schematic diagram of the structure of a top view of a driving frame in a cell separation and extraction device for testing children's blood diseases proposed by the present invention.
[0021] In the figure: 1 inspection table, 2 support legs, 3 first electric telescopic rod, 4 first motor, 5 rotating plate, 6 centrifugal port, 7 centrifugal block, 8 blood centrifugal tank, 9 rotating tank, 10 driving frame, 11 gear ring, 12 second motor, 13 gear, 14 collecting plate, 15 fixed rod, 16 annular plate, 17 rotating cover plate, 18 rotating block, 19 movable sleeve block, 20 rotating sleeve plate, 21 rubber airbag, 22 extraction tube, 23 sealing block, 24 vertical rod, 25 annular groove, 26 second electric telescopic rod, 27 slider, 28 annular baffle, 29 pressing plate, 30 limit groove, 31 limit plug rod, 32 end block, 33 spring. DETAILED DESCRIPTION
[0022] The following examples are for illustrative purposes only and are not intended to limit the scope of the present invention.
[0023] Example
[0024] Reference Figure 1-4 A cell separation and extraction device for testing children's blood diseases includes a test table 1, and four supporting legs 2 distributed in a rectangular shape are fixedly connected to the lower end of the test table 1 to play a stabilizing and supporting role. A rotating disk is rotatably connected to the upper end of the test table 1, and a first electric telescopic rod 3 is fixedly installed at the center position of the upper end of the rotating disk. The telescopic end of the first electric telescopic rod 3 is fixedly connected to a rotating plate 5. A first motor 4 that drives the rotating disk to rotate is fixedly installed at the lower end of the test table 1. The first motor 4 can drive the first electric telescopic rod 3 to rotate, so that the rotating plate 5 can be lifted and rotated at the same time.
[0025] A collecting tray 14 is provided at the upper end of the test table 1 and at the left side of the first electric telescopic rod 3 , and is provided with test tubes for collecting children's blood after extraction.
[0026] A circular centrifugal opening 6 is provided on the test bench 1 and at the right side of the first electric telescopic rod 3. A centrifugal block 7 is rotatably connected to the inner peripheral wall of the centrifugal opening 6. A plurality of groups of blood centrifugal grooves 8 are circumferentially provided on the centrifugal block 7. Each group of blood centrifugal grooves 8 is composed of at least two blood centrifugal grooves 8. The blood centrifugal grooves 8 are used to present the blood of children to be tested. A rotating groove 9 is provided at the center of the upper end of the centrifugal block 7. A driving frame 10 with a regular hexagonal inner wall is rotatably connected to the upper end of the test bench 1 and at the outer side of the centrifugal opening 6. The outer peripheral wall of the driving frame 10 is circular and fixedly sleeved with a gear ring 11. A second motor 12 is fixedly embedded on the upper end of the test bench 1. A gear 13 is fixedly sleeved on the output end of the second motor 12. The gear 13 is meshed with the gear ring 11. The gear 13 is driven to rotate by the second motor 12, so that the gear 13 drives the driving frame 10 to rotate in a state of meshing with the gear ring 11.
[0027] An extraction mechanism is provided at the lower end of the rotating plate 5 and at a corresponding position above the centrifugal port 6. The extraction mechanism includes a fixed rod 15 fixedly connected to the lower end of the rotating plate 5 and concentrically arranged with the centrifugal block 7. The lower end of the fixed rod 15 is rotatably connected to a rotating cover plate 17 with the same shape as the inner wall of the driving frame 10. A rotating block 18 is fixedly connected to the center position of the lower end of the rotating cover plate 17. The rotating block 18 and the rotating groove 9 correspond in position and are both regular hexagonal structures. When the first electric telescopic rod 3 drives the rotating cover plate 17 to move downward, it can be directly inserted into the driving frame 10 and arranged in a fit therewith. At the same time, the rotating block 18 is inserted into the rotating groove 9. Then, when the second motor 12 drives the driving frame 10 to rotate, the rotating cover plate 17 rotates synchronously therewith, and under the transmission action of the rotating block 18 and the rotating groove 9, the centrifugal block 7 also rotates synchronously, thereby performing the centrifugal work of the children's blood.
[0028] A movable sleeve block 19 is slidably sleeved on the fixed rod 15, and the movable sleeve block 19 can slide up and down along the fixed rod 15. A rotating sleeve plate 20 is rotatably sleeved on the movable sleeve block 19, and the rotating sleeve plate 20 can rotate around the movable sleeve block 19, so that the rotating sleeve plate 20 can both slide up and down and rotate. A rubber air bag 21 is fixedly connected to the upper end of the rotating sleeve plate 20 and at the corresponding position of each blood centrifuge tank 8. The lower end of each rubber air bag 21 is connected to a liquid extraction tube 22. The lower end of the liquid extraction tube 22 passes through the rotating cover plate 17. The rubber air bag 21 and the liquid extraction tube 22 are used to extract the separated children's blood.
[0029] Four vertical rods 24 are evenly circumferentially fixedly connected to the upper end of the rotating sleeve 20, and an annular plate 16 is commonly fixedly connected to the upper end of each vertical rod 24. The annular plate 16 is sleeved on the fixed rod 15. An annular groove 25 with a T-shaped cross-section is opened on the upper end of the annular plate 16. A slider 27 is slidably connected in the annular groove 25. A second electric telescopic rod 26 is fixedly installed on the rotating plate 5. The telescopic end of the second electric telescopic rod 26 extends into the annular groove 25 and is fixedly connected to the upper end of the slider 27. The second electric telescopic rod 26 can control the position height of the rotating sleeve 20 through the connection between the slider 27 and the annular groove 25 without affecting the rotation of the rotating sleeve 20.
[0030] The lower end of the rotating cover 17 and the corresponding position of each liquid extraction tube 22 are fixedly connected with a sealing block 23, and the sealing block 23 is sleeved on the corresponding liquid extraction tube 22. When the rotating cover 17 is moved down to cover the centrifugal block 7, the sealing block 23 can be inserted into the corresponding blood centrifugal tank 8 to ensure that the blood will not overflow during centrifugation.
[0031] Annular baffles 28 are fixedly connected to the upper end of the rotating sleeve 20 and at the outer and inner sides of the rubber airbags 21. Each rubber airbag 21 is located between the two annular baffles 28. An annular pressing plate 29 is slidably connected to the opposite side of the two annular baffles 28. The pressing plate 29 is fixedly connected to the upper end of each rubber airbag 21, and the rubber airbag 21 can be compressed by pressing the pressing plate 29. Limiting grooves 30 are provided at both ends of the pressing plate 29, and limiting rods 31 are horizontally inserted on the corresponding positions of the outer annular baffle 28 and below the limiting grooves 30. The end of the limiting rod 31 away from the annular baffle 28 is fixedly connected to an end block 32, and a spring 33 is fixedly connected between the end block 32 and the annular baffle 28. The spring 33 is sleeved on the corresponding limiting rod 31. When the pressing plate 29 is pressed a certain distance, the limiting rod 31 can be inserted into the corresponding limiting groove 30, and then the pressing plate 29 will not move under the elastic action of the rubber airbag 21 and keep its position unchanged.
[0032] After the children's blood is placed in each blood centrifuge tank 8, it is only necessary to press the pressing plate 29 in advance and use the limiting plug rod 31 to position it so that the rubber airbag 21 remains in a compressed state, and then the rotating cover plate 17 is driven by the first electric telescopic rod 3 to move down and insert it into the driving frame 10 and cover the centrifugal block 7, so that the second motor 12 can directly drive the centrifugal block 7 and the rotating cover plate 17 to rotate synchronously, so that the children's blood is centrifuged in the blood centrifuge tank 8. After the centrifugation is completed, the blood is statically layered. At this time, it is only necessary to control the up and down movement of the rotating sleeve plate 20 by the second electric telescopic rod 26 to move each liquid extraction tube 22 downward and insert it into the layered children's blood. After moving down to an appropriate length as needed, the limiting plug rod 31 is pulled out to move the pressing plate 29 upward, the rubber airbag 21 is restored, and suction is generated to suck the corresponding blood cells into the liquid extraction tube 22. Then, it is only necessary to control the lifting and rotation of the first electric telescopic rod 3 to extract the sucked blood cells into the collection tray 14.
[0033] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims
1. A cell separation and extraction device for testing children's blood diseases, comprising a testing table (1), characterized in that: The lower end of the test bench (1) is fixedly connected to four supporting legs (2) distributed in a rectangular shape, the upper end of the test bench (1) is rotatably connected to a rotating disk, a first electric telescopic rod (3) is fixedly installed at the center position of the upper end of the rotating disk, the telescopic end of the first electric telescopic rod (3) is fixedly connected to a rotating plate (5), a circular centrifugal opening (6) is provided on the test bench (1) and at the right side of the first electric telescopic rod (3), a centrifugal block (7) is rotatably connected on the inner peripheral wall of the centrifugal opening (6), a plurality of groups of blood centrifugal grooves (8) are provided on the centrifugal block (7) in a circumferential direction, a rotating groove (9) is provided at the center position of the upper end of the centrifugal block (7), a driving frame (10) whose inner wall is a regular hexagon is rotatably connected to the upper end of the test bench (1) and at the outer side of the centrifugal opening (6), the outer peripheral wall of the driving frame (10) is circular and fixedly sleeved with a gear ring (11); An extraction mechanism is provided at the lower end of the rotating plate (5) and at a corresponding position above the centrifugal port (6), the extraction mechanism comprising a fixed rod (15) fixedly connected to the lower end of the rotating plate (5) and arranged concentrically with the centrifugal block (7), the lower end of the fixed rod (15) being rotatably connected to a rotating cover plate (17) having the same shape as the inner wall of the driving frame (10), the lower end of the rotating cover plate (17) being fixedly connected to a rotating block (18) at the center position, a movable sleeve block (19) being slidably sleeved on the fixed rod (15), a rotating sleeve plate (20) being rotatably sleeved on the movable sleeve block (19), the upper end of the rotating sleeve plate (20) being fixedly connected to a rubber air bag (21) at a corresponding position of each blood centrifugal tank (8), the lower end of each rubber air bag (21) being connected to a liquid extraction tube (22), the lower end of the liquid extraction tube (22) being arranged to penetrate the rotating cover plate (17); The upper end of the rotating sleeve plate (20) is evenly and circumferentially fixedly connected to four vertical rods (24), and the upper ends of the vertical rods (24) are commonly and fixedly connected to an annular plate (16), the annular plate (16) is sleeved on the fixed rod (15), and the upper end of the annular plate (16) is provided with an annular groove (25) with a T-shaped cross section, and a slider (27) is slidably connected in the annular groove (25), and a second electric telescopic rod (26) is fixedly installed on the rotating plate (5), and the telescopic end of the second electric telescopic rod (26) extends into the annular groove (25) and is fixedly connected to the upper end of the slider (27); An annular baffle plate (28) is fixedly connected to the upper end of the rotating sleeve (20) and at the outer and inner positions of the rubber airbag (21). Each of the rubber airbags (21) is located between the two annular baffle plates (28). An annular pressing plate (29) is slidably connected to the opposite side of the two annular baffle plates (28). The pressing plate (29) is fixedly connected to the upper end of each rubber airbag (21). Limiting grooves (30) are provided at both left and right ends of the pressing plate (29). A limiting plug rod (31) is transversely inserted at a corresponding position on the annular baffle plate (28) located on the outer side and below the limiting groove (30). An end block (32) is fixedly connected to the end of the limiting plug rod (31) away from the annular baffle plate (28). A spring (33) is fixedly connected between the end block (32) and the annular baffle plate (28). The spring (33) is sleeved on the corresponding limiting plug rod (31).
2. The cell separation and extraction device for testing children's blood diseases according to claim 1, characterized in that: A first motor (4) for driving the rotating disk to rotate is fixedly mounted on the lower end of the inspection table (1).
3. The cell separation and extraction device for testing children's blood diseases according to claim 1, characterized in that: A second motor (12) is fixedly embedded on the upper end of the inspection table (1), a gear (13) is fixedly sleeved on the output end of the second motor (12), and the gear (13) is meshed with the gear ring (11).
4. The cell separation and extraction device for testing children's blood diseases according to claim 1, characterized in that: A collecting tray (14) is provided at the upper end of the inspection table (1) and on the left side of the first electric telescopic rod (3).
5. The cell separation and extraction device for testing children's blood diseases according to claim 1, characterized in that: The rotating block (18) and the rotating groove (9) are located in corresponding positions and are both regular hexagonal structures.
6. The cell separation and extraction device for testing children's blood diseases according to claim 1, characterized in that: A sealing block (23) is fixedly connected to the lower end of the rotating cover plate (17) and the corresponding position of each liquid extraction pipe (22), and the sealing block (23) is sleeved on the corresponding liquid extraction pipe (22).
Citation Information
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