A fecal sampling device

Abstract

The present disclosure provides a fecal sampling device, including a sample storage tube, in which a sampling spoon is fitted and installed. A cover body is fitted and installed at the top of the sample storage tube. The sampling spoon is rotatably installed below the cover body. A driving rod for driving the rotation of the sampling spoon is arranged above the cover body. A plurality of sample inlet holes are arranged on the side surface of the sampling spoon. An automatically resetting switch plate for dipping fecal samples is rotatably installed at the bottom of the sampling spoon. This device is convenient for sampling, simple and easy to operate.

Description

Technical Field

[0001] The present invention relates to a test device, and more particularly to a fecal sampling device. Background Art

[0002] According to the statistics of the number of newly diagnosed cancer cases in China in 2020, colorectal cancer is the second most common cancer in China. In 2020, the number of new cases was approximately 560,000, and the number of deaths was approximately 250,000, seriously threatening the health of residents.

[0003] The Molecular Diagnostics Group of the Chinese Society of Laboratory Medicine published the "Chinese Expert Consensus on Experimental Diagnostic Techniques for Early Colorectal Cancer and Precancerous Lesions" in the Chinese Journal of Laboratory Medicine, consensusing that fecal DNA testing is a recommended screening method.

[0004] Therefore, fecal sampling is a relatively crucial step. The convenience of fecal sampling and the sampling volume affect the subsequent experimental test results.

[0005] According to the existing research results, it is found that most of the existing fecal sampling devices are used for the biochemical detection of fecal samples and cannot meet the needs of fecal DNA testing. Summary of the Invention

[0006] Aiming at the problem of fecal sampling for fecal DNA testing that is currently lacking, the present invention provides a fecal sampling device, which is convenient to use and has a low cost.

[0007] A fecal sampling device includes a sample storage tube, a sampling spoon is fitted and installed in the sample storage tube, a cover body is fitted and installed at the top of the sample storage tube, the sampling spoon is rotatably installed under the cover body, a driving rod for driving the sampling spoon to rotate is arranged above the cover body, a plurality of sample inlet holes are arranged on the side surface of the sampling spoon, and an automatic reset switch plate for dipping the fecal sample is rotatably installed at the bottom of the sampling spoon.

[0008] Preferably, a guide sleeve is arranged at the top of the cover body, the driving rod is slidably installed in the guide sleeve, a transmission device is arranged below the driving rod, and the transmission device is in transmission connection with the sampling spoon.

[0009] Preferably, the transmission device includes a transmission rod, a first transmission tooth is arranged at the top of the transmission rod, a second transmission tooth is arranged at the bottom of the driving rod and is matched with the first transmission tooth, the transmission rod is rotatably installed in the guide sleeve, a one-way bearing is connected to the outside of the transmission rod, and the one-way bearing is rotatably connected to the top end of the sampling spoon.

[0010] Preferably, a driving rod return spring is installed in the guide sleeve.

[0011] Preferably, the sampling spoon includes a connecting rod at the upper part and a tubular body at the lower part, and the automatic reset switch board is installed at the bottom of the tubular body.

[0012] Preferably, the automatic reset switch board includes a support shaft installed at the center of the bottom of the tubular body, and switch boards are hinged on both the left and right sides of the support shaft.

[0013] Preferably, a switch board reset spring is arranged above each switch board, and the other end of the switch board reset spring is connected to the inner wall of the top of the tubular body.

[0014] Preferably, a limiting baffle for limiting the switch board is arranged on the inner wall of the bottom of the tubular body.

[0015] Advantages of the present invention:

[0016] (1) This device contains a sampling spoon and a sample storage tube, and the tube can hold fecal preservation solution to prevent DNA degradation.

[0017] (2) The rotation movement of the sampling spoon is realized by simple pressing, so that the sample is fully released into the tube under the action of centrifugation, and the dissolution is efficient and rapid.

[0018] (3) This fecal sampling spoon can also be used in combination with the common 50 mL centrifuge tubes on the current market, with good versatility and flexible use. Description of the Drawings

[0019] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the following drawings are only some embodiments of the present application. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0020] Figure 1 is the overall structural schematic diagram of the present invention;

[0021] Figure 2 is Figure 1 the enlarged view of C in

[0022] Figure 3 is Figure 1 the sectional view taken along the line A-A in

[0023] Figure 4 is Figure 1 the sectional view taken along the line B-B in

[0024] Figure 5 is the usage state diagram of the sampling spoon. Detailed Embodiments

[0025] Next, the technical solutions in the embodiments of the present application will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments of the present application, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present application.

[0026] The present invention discloses a fecal sampling device as Figures 1-5 shown. The device includes a sample storage tube 4 for storing samples and a sampling spoon for sampling. The sampling spoon is integrally and rotatably connected to a cover body 13 that is threadedly connected to the top of the sample storage tube 4. That is, when the cover body 13 is unscrewed and separated from the sample storage tube 4, holding the cover body 13, the sampling spoon can be taken away together. An orientation sleeve 2 is integrally connected above the cover body 13. Inside the orientation sleeve 2, there is a cross-shaped guiding groove as Figure 4 shown. The driving rod 1 is slidably installed in the orientation sleeve 2 and can move up and down along the guiding groove. A one-way second transmission tooth is machined at the bottom of the driving rod 1. Below the driving rod 1, a transmission rod 7 is rotatably installed in the orientation sleeve 2. A one-way first transmission tooth is machined at the top of the transmission rod 7, and the first transmission tooth is arranged in cooperation with the second transmission tooth. A driving rod return spring 6 is also installed in the orientation sleeve 2. A one-way bearing 8 is sleeved outside the transmission rod 7. A connecting rod 3 is sleeved outside the one-way bearing 8. A tubular body 12 is installed below the connecting rod 3. The connecting rod 3 and the tubular body 12 form a sampling spoon structure.

[0027] A plurality of sample inlet holes are provided on the side wall of the tubular body 12. A support shaft 10 is installed at the bottom of the tubular body 12. On the left and right sides of the support shaft 10, a switch plate 5 is rotatably connected respectively. The outer shape of the switch plate 5 is matched with the inner wall of the tubular body 12. Four limit baffles 11 are installed on the inner wall of the bottom of the tubular body to limit the downward movement of the edge of the switch plate 5, so that the lowest position of the two switch plates 5 in the horizontal state just seals the inside of the tubular body 12. Above each switch plate 5, a switch plate return spring 9 is connected. The other end of the switch plate return spring 9 is connected to the inner wall of the top of the tubular body 12.

[0028] When the device is in use, hold the cover body 13 and insert the tubular body 12 into the feces. Under the thrust of the feces, the switch plate 5 is lifted upward along the support shaft 10 to such as Figure 5In the state shown, the fecal sample enters the inner cavity of the tubular body 12 from the sampling hole and the gap between the switch plate 5 and the tubular body 12. The hand-held cover 13 moves upward to separate from the feces. The switch plate 5 falls back to the horizontal state under the action of the switch plate return spring 9, storing the fecal sample in the tubular body 12. The cover 13 is screwed into the sample storage tube 4 containing the diluent. After tightening, the drive rod 1 is pressed downward. During the downward movement of the drive rod 1, the second transmission gear pushes the first transmission gear, which in turn pushes the transmission rod 7 to rotate by a set angle. The transmission rod 7 drives the connecting rod 3 to rotate through the one-way bearing 8, thereby realizing the rotation of the tubular body 12 at the bottom of the connecting rod 3. The drive rod 1 is released and separated from the transmission rod 7 under the action of the drive rod return spring 6. The connecting rod 3 drives the tubular body 12 to continue rotating under inertia. The fecal sample located inside the tubular body 12 is separated from the sampling hole of the tubular body 12 under the action of centrifugal force and mixed with the diluent.

[0029] In this device, the mass of the feces extracted by the sampling spoon each time is about 10g ± 3g, which is convenient for semi-quantification and helps with the quality control of subsequent DNA.

[0030] The material of the device can be prepared from materials including but not limited to PP, PVC, etc.

[0031] The above description of the disclosed embodiments enables those skilled in the art to implement or use the present application. Various modifications to these embodiments will be obvious to those skilled in the art. The general principles defined herein can be implemented in other embodiments without departing from the spirit or scope of the present application. Therefore, the present application will not be limited to these embodiments shown herein, but will conform to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A fecal sampling device, characterized in that, it includes a sample storage tube (4), a sampling spoon is fitted and installed inside the sample storage tube, a cover body (13) is fitted and installed at the top of the sample storage tube, the sampling spoon is rotatably installed below the cover body, a driving rod (1) for driving the sampling spoon to rotate is arranged above the cover body, a plurality of sample inlet holes are arranged on the side surface of the sampling spoon, and an automatic reset switch plate for dipping fecal samples is rotatably installed at the bottom of the sampling spoon; The sampling spoon includes a connecting rod (3) at the upper part and a tubular body (12) at the lower part, and the automatic reset switch plate is installed at the bottom of the tubular body (12); The automatic reset switch plate includes a support shaft (10), the support shaft (10) is installed at the center of the bottom of the tubular body (12), and switch plates (5) are hinged on both the left and right sides of the support shaft (10); A switch plate return spring (9) is connected above each switch plate (5), and the other end of the switch plate return spring (9) is connected to the inner wall of the top of the tubular body (12); A guide sleeve (2) is arranged at the top of the cover body, the driving rod (1) is slidably installed in the guide sleeve (2), a transmission device is arranged below the driving rod (1), and the transmission device is in transmission connection with the sampling spoon; The transmission device includes a transmission rod (7), a first transmission tooth is arranged at the top of the transmission rod (7), a second transmission tooth for cooperating with the first transmission tooth is arranged at the bottom of the driving rod, the transmission rod (7) is rotatably installed in the guide sleeve (2), a one-way bearing (8) is connected to the outside of the transmission rod (7), and the one-way bearing (8) is rotatably connected to the top end of the sampling spoon; A driving rod return spring (6) is installed in the guide sleeve (2); When this fecal sampling device is in use, hold the cover body (13) by hand, insert the tubular body (12) into feces, the switch plate (5) is lifted upward along the support shaft (10) under the action of the feces thrust, and the fecal sample enters the inner cavity of the tubular body (12) from the sample inlet hole and the gap between the switch plate (5) and the tubular body (12). Hold the cover body (13) and move upward to separate from the feces. The switch plate (5) falls back to the horizontal state under the action of the switch plate return spring (9), and stores the fecal sample in the tubular body (12) in the tubular body (12). Screw the cover body (13) into the sample storage tube (4) containing diluent, and press the driving rod (1) downward after tightening. During the downward movement of the driving rod (1), the second transmission tooth pushes the first transmission tooth and then pushes the transmission rod (7) to rotate by a set angle. The transmission rod (7) drives the connecting rod (3) to rotate through the one-way bearing (8), and then realizes the rotation of the tubular body (12) at the bottom of the connecting rod (3). Release the driving rod (1), and the driving rod (1) separates from the transmission rod (7) under the action of the driving rod return spring (6). The connecting rod (3) drives the tubular body (12) to continue rotating under the action of inertia, and the fecal sample located inside the tubular body (12) separates from the sample inlet hole of the tubular body (12) under the action of centrifugal force and mixes with the diluent.

2. A fecal sampling device according to claim 1, characterized in that, Above each switch board (5), a switch board return spring (9) is provided, and the other end of the switch board return spring (9) is connected to the inner wall of the top of the tubular body (12).

3. A fecal sampling device according to claim 2, wherein, a limiting baffle (11) for limiting the switch board (5) is provided on the inner wall of the bottom of the tubular body (12).

Images