Sunscreen composition with spectral selectivity and its application

Abstract

The present application discloses a sunscreen composition with spectral selectivity and its application. The sunscreen composition contains titanium dioxide and FeO(OH)·H2O. The sunscreen composition combines titanium dioxide and FeO(OH)·H2O and has spectral selectivity of transmitting beneficial light and blocking harmful light, thereby achieving selective protection of the spectrum and beauty and skin care effects.

Description

Technical Field

[0001] The present application relates to the field of cosmetic technology, and in particular to a spectrally selective sunscreen composition and application thereof. Background Art

[0002] As consumers become more aware of photoaging and cosmetic technology continues to develop, sun protection has become a necessary step in skin care. However, current sun protection technology only focuses on blocking or absorbing light, and does not differentiate between harmful and beneficial light in the sun. This results in consumers losing the benefits of sunlight while avoiding photodamage after applying sunscreen products.

[0003] There are many reports in the academic community about the recognition of beneficial light. For example, the Daniel group (Regulation of SkinCollagen Metabolism In Vitro Using a Pulsed 660nm LED Light Source: ClinicalCorrelation with a Single-Blinded Study) found that 660nm yellow light can positively affect the appearance of the skin by reducing the expression of metalloproteinase MMP-1 and upregulating the production of collagen; the Alexander group (AControlled Trial to Determine the Efficacy of Red and Near-Infrared LightTreatment in Patient Satisfaction,Reduction of Fine Lines,Wrinkles,SkinRoughness,and Intradermal Collagen Density Increase) reported that 570-810nm light showed a positive effect on skin regeneration and the increase of intradermal collagen. Summary of the invention

[0004] In response to the above technical problems, the present application provides a sunscreen composition, which can achieve spectrally selective protection, so that it can effectively filter out harmful light of 280-550nm in sunlight and transmit beneficial light of 550-760nm to the greatest extent.

[0005] The specific technical solutions of this application are as follows:

[0006] 1. A sunscreen composition, wherein the sunscreen composition contains titanium dioxide and FeO(OH)·H2O.

[0007] 2. The sunscreen composition according to item 1, wherein the mass ratio of titanium dioxide to the iron element in FeO(OH)·H2O is 15-2:1, preferably 6-2.2:1.

[0008] 3. The sunscreen composition according to any one of items 1 to 2, wherein the selectivity index of the sunscreen composition is above 0.70, preferably 0.70-0.90.

[0009] 4. The sunscreen composition according to any one of items 1 to 3, wherein the sunscreen composition further comprises cosmetically acceptable excipients and functional ingredients.

[0010] 5. Use of the sunscreen composition according to any one of items 1 to 4 in cosmetics.

[0011] 6. Use of the sunscreen composition according to any one of items 1 to 4 in selective sunscreen.

[0012] 7. The use according to item 6, wherein the selective sun protection comprises transmitting beneficial light.

[0013] 8. The use according to item 6 or 7, wherein the selective sun protection comprises blocking harmful light.

[0014] 9. The use according to any one of items 6 to 8, wherein the composition is used for beauty and skin care.

[0015] Effects of the Invention

[0016] The sunscreen composition described in the present application combines titanium dioxide and FeO(OH)·H2O, which can transmit beneficial light and block harmful light, thereby achieving highly selective protection and beauty effects on the spectrum. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the transmittance of sunscreen compositions numbered 1 to 11 at different wavelengths.

[0018] Figure 2 It is a schematic diagram of the transmittance of sunscreen compositions numbered 12 to 19 at different wavelengths.

[0019] Figure 3 It is a schematic diagram of the transmittance of sunscreen compositions numbered 20 to 21 at different wavelengths.

[0020] Figure 4 is a graphical representation of the selectivity index of sunscreen compositions numbered 1 to 11.

[0021] Figure 5Schematic diagram of the selectivity index of sunscreen compositions numbered 2 to 5 and 12 to 19, wherein I is the sunscreen composition numbered 2 and 12 to 13, II is the sunscreen composition numbered 3 and 14 to 15, III is the sunscreen composition numbered 4 and 16 to 17, and IV is the sunscreen composition numbered 5 and 18 to 19. DETAILED DESCRIPTION

[0022] The present application is described in detail below in conjunction with the described embodiments. Although specific embodiments of the present application are shown, it should be understood that the present application can be implemented in various forms and should not be limited by the embodiments set forth herein. On the contrary, these embodiments are provided to enable a more thorough understanding of the present application and to enable the scope of the present application to be fully communicated to those skilled in the art.

[0023] It should be noted that certain words are used in the specification and claims to refer to specific components. Those skilled in the art should understand that technicians may use different nouns to refer to the same component. This specification and claims do not use the difference in nouns as a way to distinguish components, but use the functional differences of components as the criterion for distinction. As mentioned throughout the specification and claims, "including" or "comprising" are open-ended terms and should be interpreted as "including but not limited to". The subsequent description of the specification is a preferred embodiment of the present application, but the description is based on the general principles of the specification and is not intended to limit the scope of the present application. The scope of protection of the present application shall be determined by the attached claims.

[0024] The present application provides a sunscreen composition, which contains titanium dioxide and FeO(OH)·H2O.

[0025] The sunscreen composition described in the present application can selectively transmit beneficial light and block harmful light, thereby achieving spectrally selective protection.

[0026] In the present application, the spectral selectivity refers to the extent to which the sunscreen filters harmful light in the range of 280-550 nm and transmits beneficial light in the range of 550-760 nm in sunlight.

[0027] In some embodiments, the ratio of the mass of the titanium dioxide to the mass of the iron element in FeO(OH)·H2O is 15-2:1, preferably 6-2.2:1.

[0028] For example, the ratio of the mass of titanium dioxide to the mass of iron in FeO(OH)·H2O (m 二氧化钛 :m FeO(OH)·H2O中的铁元素) can be 15:1, 14:1, 13:1, 12:1, 11:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2.9:1, 2.8:1, 2.7:1, 2.6:1, 2.5:1, 2.4:1, 2.3:1, 2.2:1, 2.1:1, 2:1, etc.

[0029] In some embodiments, the selectivity index of the sunscreen composition is above 0.70, preferably 0.70-0.90.

[0030] For example, the selectivity index of the sunscreen composition is 0.70, 0.71, 0.72, 0.73, 0.74, 0.75, 0.76, 0.77, 0.78, 0.79, 0.80, 0.81, 0.82, 0.83, 0.84, 0.85, 0.86, 0.87, 0.88, 0.89, 0.90, etc.

[0031] In this application, the selectivity index is defined by the following formula:

[0032]

[0033] Wherein, T is the transmittance of the composition at a certain wavelength;

[0034] λ is the wavelength;

[0035] σ is the integrated value of transmittance from 280nm to 760nm.

[0036] When the selectivity index is high, it indicates that the selective protection effect is good. The selectivity index (SI) of the sunscreen composition described in the present application is above 0.70, indicating that the sunscreen composition described in the present application has a good selective protection effect and can achieve good spectral selectivity.

[0037] In the present application, there is no limitation on the preparation method of the sunscreen composition, which can be prepared according to conventional methods in the art, for example, titanium dioxide and FeO(OH)·H2O can be dissolved in a solvent and ultrasonicated to obtain the sunscreen composition.

[0038] In the present application, there is no limitation on the solvent for dissolving titanium dioxide and FeO(OH)·H2O, which may be a commonly used solvent in the art, for example, the solvent may be diethylhexyl carbonate, alcohols (for example, propylene glycol, butylene glycol, etc.), fatty acid esters (for example, caprylic / capric fatty acid esters, glyceryl laurate, etc.), silanes (for example, polysiloxanes, polymethylsiloxanes, etc.), ethers (for example, myristyl alcohol polyether, tridecyl alcohol polyether, etc.), etc.

[0039] In the present application, there is no limitation on the amount of solvent used, and the solvent can be added according to the conventional amount in the art. For example, the solvent is 30-90% by mass in the sunscreen composition. For example, the solvent can be 30%, 40%, 50%, 60%, 70%, 80%, or 90%.

[0040] In the present application, there is no limitation on the mass percentage of titanium dioxide and FeO(OH)·H2O in the sunscreen composition, as long as the mass ratio of titanium dioxide to the mass ratio of iron in FeO(OH)·H2O is within the range of 15-2:1. For example, the total amount of titanium dioxide and FeO(OH)·H2O is 0.01-50% in terms of mass percentage in the sunscreen composition. Specifically, it can be 0.01%, 0.05%, 0.1%, 0.5%, 1%, 5%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, etc.

[0041] In the present application, the sunscreen composition may also contain cosmetically acceptable excipients and other functional ingredients, but titanium dioxide and FeO(OH)·H2O are the active ingredients that must be present in the sunscreen composition.

[0042] The cosmetically acceptable auxiliary materials are the auxiliary materials commonly used in the art, such as oils, emulsifiers, preservatives, flavors, etc.

[0043] The functional ingredients include other sunscreen ingredients and skin care ingredients. For example, the sunscreen ingredients may be solid sunscreens or liquid sunscreens. The solid sunscreens may be, for example, homosalate, ethylhexyl salicylate, isoamyl p-methoxycinnamate, ethylhexyl methoxycinnamate, octocrylene, dimethyl PABA ethylhexyl, polysilicone-15, etc.; the liquid sunscreens may be, for example, benzophenone-3, benzophenone-4, phenylbenzimidazole sulfonic acid, 4-methylbenzylidene camphor, ethylhexyl triazone, diethylhexyl butyramido triazone, anthranilate menthyl, butyl methoxydibenzoylmethane, terephthalylidene dicamphor sulfonic acid, disodium phenyl dibenzimidazole tetrasulfonate, diethylamino hydroxybenzoyl hexyl benzoate, drometrizole trisiloxane, methylene bis-benzotriazolyl tetramethylbutylphenol, bis-ethylhexyloxyphenol methoxyphenyl triazine, etc. The skin care ingredients may be, for example, hyaluronic acid substances, polypeptide substances, etc.

[0044] The present application provides use of the above-mentioned sunscreen composition in cosmetics.

[0045] The present application provides use of the sunscreen composition described above in selective sunscreen.

[0046] In some embodiments, the selective sun protection comprises transmitting beneficial light.

[0047] In some embodiments, the selective sun protection comprises blocking harmful light.

[0048] In some embodiments, the sunscreen composition can be used for beauty and skin care because it can transmit beneficial light.

[0049] For example, the cosmetic skin care is to reduce the expression of metalloproteinase MMP-1, promote collagen production and / or skin regeneration.

[0050] Example

[0051] The present application provides a general and / or specific description of the materials and test methods used in the experiments. In the following examples, unless otherwise specified, % represents wt%, i.e., weight percentage. The reagents or instruments used without indicating the manufacturer are all conventional reagent products that can be obtained commercially. The raw materials and equipment used in the examples and comparative examples are shown in Table 1.

[0052] Table 1

[0053] Reagents / Instruments Manufacturer information <![CDATA[TiO2]]> Uni-powder <![CDATA[FeO(OH)H2O]]> Uni-powder Diethylhexyl carbonate Evonik Operations GmbH Octocrylene DSM Balance <![CDATA[OHAUS,Adventurer TM ]]> Ultrasonic Disperser Xinzhi Biotechnology, SB-5200DTD UV-Vis Spectrophotometer METTLER TOLEDO, UV5nano Cuvette Tansoole, white quartz cuvette with lid, 12.5*12.5*45

[0054] Example 1

[0055] Titanium dioxide and FeO(OH)·H2O were dissolved in 10 ml of diethylhexyl carbonate, and ultrasonicated at 25°C and 40 kHz for 5 min until the sample was completely dispersed to obtain sunscreen compositions, which were numbered 2 to 5, and the mass percentages of titanium dioxide and FeO(OH)·H2O in the compositions and the mass ratios of iron elements in titanium dioxide and FeO(OH)·H2O are shown in Table 2.

[0056] Example 2

[0057] Titanium dioxide, FeO(OH)·H2O and octocrylene were dissolved in 10 ml of diethylhexyl carbonate, and ultrasonicated at 25°C and 40 kHz for 5 min until the sample was completely dispersed to obtain a sunscreen composition, which was numbered 20-21, wherein the mass percentages of titanium dioxide, FeO(OH)·H2O and octocrylene in the composition and the mass ratio of iron in titanium dioxide and FeO(OH)·H2O are shown in Table 2.

[0058] Comparative Example 1

[0059] The sunscreen compositions were prepared in the same manner as in Example 1 and were numbered 1 and 6 to 19, wherein the mass percentages of titanium dioxide and FeO(OH)·H2O or other iron oxides in the compositions and the ratio of the mass of titanium dioxide to the mass of the iron element in FeO(OH)·H2O or other iron oxides were as shown in Table 2.

[0060] Table 2

[0061]

[0062]

[0063] Experimental Example 1 Determination of light transmittance

[0064] The sunscreen compositions (numbered 1 to 21) described in the examples and comparative examples were diluted, and 300 μL of the diluted sample solution was placed in a cuvette to measure the transmittance in different wavelength ranges. The results are as follows: Figure 1 , Figure 2 and Figure 3 shown.

[0065] from Figure 1 , Figure 2 and Figure 3 It can be seen that the sunscreen compositions shown in the examples and comparative examples have light transmittance (T) at different wavelengths.

[0066] Experimental Example 2 Determination of Selectivity Index

[0067] According to the transmittance of the sunscreen compositions (numbered 1 to 21) described in the examples and comparative examples at a wavelength of 280-760 nm, the selectivity index was calculated according to the following formula, and the results are shown in Tables 3 and Figure 4 , Figure 5 As shown, Figure 5 In the above description, I is the sunscreen composition numbered 2 and 12 to 13, II is the sunscreen composition numbered 3 and 14 to 15, III is the sunscreen composition numbered 4 and 16 to 17, and IV is the sunscreen composition numbered 5 and 18 to 19.

[0068]

[0069] Wherein, T is the transmittance of the composition at a certain wavelength;

[0070] λ is the wavelength;

[0071] σ is the integrated value of transmittance from 280nm to 760nm.

[0072] Table 3 Selectivity index of different sunscreen compositions

[0073] Composition No. Selectivity Index (SI) 1 0.69 2 0.72 3 0.74 4 0.88 5 0.70 6 0.56 7 0.50 8 0.45 9 0.47 10 0.43 11 0.38 12 0.59 13 0.60 14 0.43 15 0.43 16 0.37 17 0.23 18 0.28 19 0.01 20 0.74 21 0.74

[0074] From Table 3 and Figure 4-Figure 5 It can be seen that different sunscreen compositions have different selectivity indexes. When titanium dioxide and FeO(OH)·H2O are combined, the highest selectivity index is shown, indicating that the composition of the present application can achieve better spectral selective protection.

[0075] From the selectivity index of the compositions No. 3, 20-21 in Table 3, it can be seen that other UV sunscreens will not affect the selectivity index of the compositions.

[0076] The above is only the preferred embodiment of the present application, and does not limit the present application in other forms. Any technician familiar with the profession may use the above disclosed technical content to change or modify it into an equivalent embodiment with equivalent changes. However, any simple modification, equivalent change and modification made to the above embodiment based on the technical essence of the present application without departing from the technical solution of the present application still falls within the protection scope of the technical solution of the present application.

Claims

1. A sunscreen composition, wherein: The sunscreen composition contains titanium dioxide and FeO(OH)·H2O; The mass ratio of titanium dioxide to the iron element in FeO(OH)·H2O is 13-2:

1.

2. The sunscreen composition according to claim 1, wherein The mass ratio of titanium dioxide to the iron element in FeO(OH)·H2O is 6-2.2:

1.

3. The sunscreen composition according to any one of claims 1 to 2, wherein The selectivity index of the sunscreen composition is above 0.70; The selectivity index is defined by the following formula: Wherein, T is the transmittance of the composition at a certain wavelength; λ is the wavelength; σ is the integrated value of transmittance from 280nm to 760nm.

4. The sunscreen composition according to claim 3, wherein The selectivity index of the sunscreen composition is 0.70-0.

90.

5. The sunscreen composition according to any one of claims 1 to 2, wherein: The sunscreen composition further comprises cosmetically acceptable auxiliary materials and functional ingredients.

6. Use of the sunscreen composition according to any one of claims 1 to 5 in the preparation of cosmetics.

7. Use of the sunscreen composition according to any one of claims 1 to 5 in the preparation of a selective sunscreen product.

8. The use according to claim 7, wherein the selective sun protection comprises transmission of beneficial light.

9. The use according to claim 7, wherein the selective sun protection comprises blocking harmful light.

10. The use according to any one of claims 7 to 9, wherein the composition is used for beauty and skin care.

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