An albumin polypeptide ultrafiltration system for enhancing immune activity

Through the combination of shaking components and backwashing tubes, the problem of hollow fiber membranes being easily blocked is solved, and the albumin peptides are efficiently isolated, enhancing immune activity and cleaning effects.

CN115999366BActive Publication Date: 2025-08-22HANGZHOU BIBAU BIOTECHNOLOGY CO LTD +1
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Patent Information

Application Number
CN202211111907.6
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2022-09-13
Publication Date
2025-08-22
Estimated Expiration
2042-09-13

AI Technical Summary

Technical Problem

In the existing ultrafiltration system, the filter holes of the hollow fiber membrane are easily blocked, resulting in a decrease in filtration effect, poor backflushing effect, and incomplete cleaning.

Method used

The hollow fiber membrane is shaken left and right by shaking the component, and combined with the cleaning of the backwashing tube, it prevents the filter hole from being blocked and improves the cleaning effect.

Benefits of technology

Effectively prevent the filtration holes of hollow fiber membranes, improve the separation efficiency of albumin polypeptides, enhance immune activity, save energy, and improve the backwashing effect.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention discloses an albumin polypeptide ultrafiltration system for enhancing immune activity, comprising a housing, a filter assembly, a water inlet pipe, a backwash pipe, a water outlet pipe, a filtrate pipe and a shaking assembly; the filter assembly comprises a plurality of hollow fiber membranes, a mounting plate one and a mounting plate two are respectively provided at both ends of the hollow fiber membrane, and the mounting plate one is provided with a plurality of through holes, and one end of the hollow fiber membrane is connected to the through hole, the mounting plate two blocks the other end of the fiber membrane, and the mounting plate one and the mounting plate two are fixedly connected by a connecting rod; the water inlet pipe is connected to one end of the housing, and the water outlet pipe is connected to the other end of the housing, a solution to be filtered is passed into the housing, and the albumin polypeptide solution is filtered out through the filter holes of the hollow fiber membrane. By driving the hollow fiber membrane to shake back and forth, the impurities attached to its outer wall are vibrated off, effectively preventing the filter holes of the hollow fiber membrane from being blocked, and improving the effect of backwashing.
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Description

Technical Field

[0001] The present invention relates to an ultrafiltration system, in particular to an albumin polypeptide ultrafiltration system for enhancing immune activity. Background Art

[0002] The main benefits and effects of albumin peptides include regulating immunity, providing antioxidant benefits, improving high-quality protein nutrition, promoting the absorption of nutrients such as calcium, iron, and nucleic acids, increasing food conversion, and regulating intestinal flora. A weakened immune system is more susceptible to infection or cancer, while abnormal immunity can also lead to harmful consequences such as allergic reactions and autoimmune diseases. Albumin peptides can promote and stimulate the proliferation of various immune organs and cells, thereby regulating the body's immunity.

[0003] During the production process of albumin polypeptides, the accompanying hydrophobic polypeptides (bitter peptides) need to be filtered out. Hydrophobic polypeptides will affect the taste of albumin polypeptides. Currently, they are generally filtered out through an ultrafiltration system. During the use of the ultrafiltration device, the filter pores may be clogged, making the effect worse and worse. Therefore, a backwash system is generally equipped. However, only using the backwash system can easily lead to incomplete cleaning, and some blockages cannot be removed. Summary of the Invention

[0004] The purpose of the present invention is to provide an albumin polypeptide ultrafiltration system for enhancing immune activity. By reciprocatingly driving the hollow fiber membrane to shake, impurities attached to its outer wall are shaken off, effectively preventing the filter holes of the hollow fiber membrane from being blocked, and at the same time improving the backwashing effect.

[0005] The above technical objectives of the present invention are achieved through the following technical solutions:

[0006] An albumin polypeptide ultrafiltration system for enhancing immune activity comprises a housing, a filter assembly, a water inlet pipe, a backwash pipe, a water outlet pipe, a filtrate pipe and a shaking assembly;

[0007] The filter assembly includes a plurality of hollow fiber membranes, each of which is provided with a mounting plate 1 and a mounting plate 2 at both ends. The mounting plate 1 is provided with a plurality of through holes, and one end of the hollow fiber membrane is connected to the through hole. The mounting plate 2 blocks the other end of the fiber membrane. The mounting plate 1 and the mounting plate 2 are fixedly connected by a connecting rod.

[0008] The water inlet pipe is connected to one end of the box, and the water outlet pipe is connected to the other end of the box. The solution to be filtered is passed into the box, and the albumin polypeptide solution is filtered out through the filter holes of the hollow fiber membrane;

[0009] The filtered filtrate is collected through the filtrate tube, and the side of the filtrate tube is connected to the backwash pipe;

[0010] The shaking assembly drives the hollow fiber membrane to move left and right.

[0011] Preferably, the shaking assembly includes a cam 1 and a clamping plate, the side of the mounting plate 2 away from the hollow fiber membrane is fixedly connected to the clamping plate, the side of the cam 1 is in contact with the clamping plate, two partitions are provided in the box body, the partitions are arranged up and down, and mounting grooves are provided in the partitions, the mounting plate 1 and the mounting plate 2 are respectively located in the mounting grooves of the upper and lower partitions, and a sliding groove is provided on the side of the mounting groove, the mounting plate 1 and the mounting plate 2 are both located in the sliding groove, and a spring is provided at one end of the sliding groove, the two springs have a certain thrust on the mounting plate 1 and the mounting plate 2 respectively, and the cam 1 is connected to a driving mechanism.

[0012] Preferably, the driving mechanism includes blades, a rotor, bevel gear 1, bevel gear 2 and a rotating shaft. The blades are located in the water inlet pipe, and the water inlet pipe has a right-angle turn. One end of the rotor is fixedly connected to the blades, and the other end of the rotor passes through the right-angle turn and is fixedly connected to bevel gear 1. Bevel gear 2 is meshed with bevel gear 1. One end of the rotating shaft is fixedly connected to bevel gear 2, and the other end passes through the box and is fixedly connected to cam 1.

[0013] Preferably, a separation cover is fixedly connected to the mounting plate, and the separation cover is an inverted bowl-shaped structure. The separation cover wraps all the through holes, and the separation cover is connected to the filtrate tube via a bellows.

[0014] Preferably, the partition located at the upper part of the box body is provided with a plurality of water holes, and the two partitions divide the inner part of the box body into three spaces: a water outlet chamber, a filtering chamber and a shaking chamber. The water inlet pipe is connected to the filtering chamber, and the hollow fiber membrane is located in the filtering chamber. The shaking assembly is located in the shaking chamber. The water outlet pipe is connected to the water outlet chamber, and the water holes connect the water outlet chamber and the filtering chamber.

[0015] Preferably, sealing grooves are provided on the upper and lower surfaces of the mounting plate 1 and the mounting plate 2, and the sealing grooves surround the mounting plate 1 or the mounting plate 2. A sealing ring is provided in the sealing groove, and the sealing ring is in close contact with the slide groove.

[0016] Preferably, a drain pipe is provided on the bottom side wall of the shaking chamber, and a valve 1 is provided on the drain pipe.

[0017] Preferably, valve two and valve three are installed on the filtrate pipe and the backwash pipe.

[0018] Preferably, a motor is installed at the bottom of the box, the output shaft of the motor passes through the shaking chamber, and the output shaft of the motor is fixedly connected to cam 2. Cam 1 and cam 2 do not affect each other, and both drive the clamping plate. When water enters the water inlet pipe for filtration, only cam 1 is used to drive the clamping plate, and the protruding end of cam 2 is away from the clamping plate. When backwashing, only cam 2 is used to drive the clamping plate.

[0019] The beneficial effects of the present invention are: 1. The albumin polypeptide can be quickly separated through the ultrafiltration system, and at the same time, the albumin polypeptide can promote and stimulate the proliferation of various immune organs and immune cells, thereby regulating the body's immunity; 2. The spring has a certain thrust on the mounting plate one and the mounting plate two, so that the clamping plate at the bottom of the mounting plate two can be tightly attached to the cam one, and at the same time, the cam one is rotated, and the cam one drives the clamping plate to move back and forth left and right in the horizontal direction, so that the mounting plate one and the mounting plate two drive the hollow fiber membrane to shake left and right, so that impurities attached to the side wall of the hollow fiber membrane can be shaken off, preventing the filter holes of the hollow fiber membrane from being blocked; 3. Clean water enters the interior of the hollow fiber membrane through the backwash pipe, and cooperates with the shaking component to effectively improve the cleaning effect of the hollow fiber membrane; 4. The slide groove in the partition provides a moving space for the movement of the mounting plate one and the mounting plate two, limiting them to left and right movement, and the sealing ring prevents the solution from passing through the mounting groove, reducing the solution from penetrating and shaking. Indoor; 5. The filtrate filtered out by the hollow fiber membrane is collected by the separation cover, separated from the solution in the water outlet chamber, and transported to the filtrate pipe through the bellows; 6. The bellows has a certain degree of flexibility, and can bend with it when the mounting plate 1 and the mounting plate 2 drive the hollow fiber membrane to move left and right; 7. The water inlet pipe has a certain pressure when introducing the solution, which can drive the blades to rotate and drive the cam 1 to rotate, thereby driving the hollow fiber membrane to move left and right during the solution filtration process, effectively preventing the hollow fiber membrane from being blocked, and effectively saving energy; 8. Cam 1 and cam 2 drive the hollow fiber membrane to move left and right. During the backwashing process, the water inlet pipe will be closed, causing the cam 1 to be unable to rotate. At this time, the motor is started to drive the cam 2 to rotate, driving the hollow fiber membrane to swing left and right, generating a certain impact force with the water flow, and washing away the tiny impurities attached to the outer wall of the hollow fiber membrane, effectively improving the washing effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 A perspective view of the present invention;

[0021] Figure 2 This is the internal structure diagram of the box;

[0022] Figure 3 is a cross-sectional structural diagram of a hollow fiber membrane;

[0023] Figure 4 for Figure 2 A magnified view of area A;

[0024] Figure 5 This is the structural diagram of the shaking mechanism;

[0025] Figure 6 It is a side sectional view of the box;

[0026] Figure 7 for Figure 6 Magnified view of area B.

[0027] Figure numerals: 1. Box body; 2. Water inlet pipe; 3. Water outlet pipe; 4. Filtrate pipe; 5. Backwash pipe; 6. Valve three; 7. Valve two; 8. Partition; 9. Shaking chamber; 10. Filter chamber; 11. Water outlet chamber; 12. Water hole; 13. Hollow fiber membrane; 14. Mounting plate one; 15. Mounting plate two; 16. Connecting rod; 17. Blade; 18. Rotor; 19. Bevel gear one; 20. Bevel gear two; 21. Rotating shaft; 22. Cam one; 23. Cam two; 24. Motor; 25. Partition cover; 26. Bellows; 27. Drain pipe; 28. Valve one; 29. ​​Clamping plate; 30. Mounting groove; 31. Slide groove; 32. Spring; 33. Sealing ring. DETAILED DESCRIPTION

[0028] See Figures 1 to 7 A albumin polypeptide ultrafiltration system for enhancing immune activity includes a box 1, a filter component, an inlet pipe 2, a backwash pipe 5, an outlet pipe 3, a filtrate pipe 4 and a shaking component. The inlet pipe 2 is connected to one end of the box 1, and the outlet pipe 3 is connected to the other end of the box 1. The solution to be filtered is introduced into the box 1, and the albumin polypeptide solution is filtered out through the filter holes of the hollow fiber membrane 13.

[0029] A filter assembly is provided in the box body 1, and the filter assembly includes a plurality of hollow fiber membranes 13. A mounting plate 14 and a mounting plate 2 15 are provided at both ends of the hollow fiber membrane 13. The partition 8 located above the box body 1 is provided with a plurality of water holes 12, and the two partitions 8 divide the interior of the box body 1 into three spaces: a water outlet chamber 11, a filter chamber 10 and a shaking chamber 9. The water inlet pipe 2 is connected to the filter chamber 10, and the hollow fiber membrane 13 is located in the filter chamber 10. The shaking assembly is located in the shaking chamber 9. The water outlet pipe 3 is connected to the water outlet chamber 11. The water holes 12 connect the water outlet chamber 11 and the filter chamber 10. The solution coming in from the water inlet pipe 2 enters the filter chamber 10 and passes through the hollow fiber membrane 13. The filtrate with albumin polypeptide enters the interior of the hollow fiber membrane 13, and it and large particle impurities enter the water outlet chamber 11 through the water holes 12, and then are discharged through the water outlet pipe 3. A drain pipe 27 is provided on the bottom side wall of the shaking chamber 9, and a valve 1 28 is provided on the drain pipe 27. The opening and closing of the drain pipe 27 is controlled by the valve 1 28, so that some solution that has seeped into the shaking chamber 9 can be discharged through the drain pipe 27, effectively preventing the shaking component from being affected. At the same time, valve 2 7 and valve 3 6 are installed on the filtrate pipe 4 and the backwash pipe 5. During the filtration process, valve 2 7 on the filtrate pipe 4 is opened, and valve 3 6 on the backwash pipe 5 is closed. When backwashing is performed, valve 2 7 on the filtrate pipe 4 is closed, valve 3 6 on the backwash pipe 5 is opened, and the water inlet pipe 2 is also closed. The clean water in the backwash pipe 5 enters the hollow fiber membrane 13, and discharges the blockage through the filter holes of the hollow fiber membrane 13, enters the filtration chamber 10, and then enters the water outlet chamber 11 through the water hole 12 and is discharged from the water outlet pipe 3.

[0030] The mounting plate 14 is provided with a plurality of through holes, and one end of the hollow fiber membrane 13 is connected to the through hole, and the mounting plate 2 15 blocks the other end of the fiber membrane. The mounting plate 14 and the mounting plate 2 15 are fixedly connected by a connecting rod 16, and the mounting plate 14 and the mounting plate 2 15 are fixed into a whole by the connecting rod 16, so that the hollow fiber membrane 13 can be stably moved left and right, and the upper and lower ends do not misalign to prevent the hollow fiber membrane 13 from breaking. A separation cover 25 is fixedly connected to the mounting plate 14. The separation cover 25 is an inverted bowl-shaped structure. The separation cover 25 wraps all the through holes. The separation cover 25 is connected to the filtrate tube 4 through a bellows 26. The filtrate filtered out by the hollow fiber membrane 13 is collected by the separation cover 25, separated from the solution in the water outlet chamber 11, and transported to the filtrate tube 4 through the bellows 26. The bellows 26 has a certain degree of flexibility. When the mounting plate 14 and the mounting plate 2 15 drive the hollow fiber membrane 13 to move left and right, it can bend with it.

[0031] A rocking assembly is provided below the mounting plate 2 15, and the rocking assembly includes a cam 1 22 and a holding plate 29. The side of the mounting plate 2 15 away from the hollow fiber membrane 13 is fixedly connected to the holding plate 29, and the side of the cam 1 22 contacts the holding plate 29. Two partitions 8 are provided in the box body 1. The partitions 8 are arranged up and down, and mounting grooves 30 are provided in the partitions 8. The mounting plate 1 14 and the mounting plate 2 15 are respectively located in the mounting grooves 30 of the upper and lower partitions 8. A slide groove 31 is provided on the side of the mounting groove 30. The mounting plate 1 14 and the mounting plate 2 15 are both located in the slide groove 31, and a spring 32 is provided at one end of the slide groove 31. The two springs 32 have a certain thrust on the mounting plate 1 14 and the mounting plate 2 15 respectively. The spring 32 has a certain thrust on the mounting plate 1 14 and the mounting plate 2 15, so that The clamping plate 29 at the bottom of the mounting plate 2 15 can be in close contact with the cam 1 22, and the cam 1 22 is rotated at the same time, and the cam 1 22 drives the clamping plate 29 to reciprocate left and right in the horizontal direction, so that the mounting plate 1 14 and the mounting plate 2 15 drive the hollow fiber membrane 13 to shake left and right, so that the impurities attached to the side wall of the hollow fiber membrane 13 can be shaken off to prevent the filter holes of the hollow fiber membrane 13 from being blocked. The upper and lower surfaces of the mounting plate 1 14 and the mounting plate 2 15 are provided with sealing grooves, which surround the mounting plate 1 14 or the mounting plate 2 15. A sealing ring 33 is provided in the sealing groove, and the sealing ring 33 is in close contact with the slide groove 31. The sealing ring 33 is used to seal the mounting plate 14, the mounting plate 2 15 and the partition 8, effectively preventing the solution from seeping into the shaking chamber 9.

[0032] Cam 1 22 is connected to a driving mechanism, which includes blades 17, rotor 18, bevel gear 19, bevel gear 20 and rotating shaft 21. Blade 17 is located in the water inlet pipe 2, and the water inlet pipe 2 has a right-angle turn. One end of the rotor 18 is fixedly connected to the blade 17, and the other end of the rotor 18 passes through the right-angle turn and is fixedly connected to bevel gear 19. Bevel gear 20 is engaged with bevel gear 19. One end of the rotating shaft 21 is fixedly connected to bevel gear 20, and the other end passes through the box body 1 and is fixedly connected to cam 1 22. During the filtration process of the ultrafiltration system, the water inlet pipe 2 passes a solution with a certain pressure into the box body 1, which will drive the blade 17 to rotate together, thereby driving bevel gear 19 and bevel gear 2 20 to rotate together through the rotor 18, and the rotating shaft 21 is driven by bevel gear 2 20 to rotate, and the rotating shaft 21 drives cam 1 22 to rotate.

[0033] A motor 24 is installed at the bottom of the box body 1. The output shaft of the motor 24 passes through the shaking chamber 9, and the output shaft of the motor 24 is fixedly connected to the cam 23. The cam 1 22 and the cam 2 23 do not affect each other, and both drive the clamping plate 29. When the water inlet pipe 2 is filtered, only the cam 1 22 is used to drive the clamping plate 29, and the protruding end of the cam 2 23 is away from the clamping plate 29. When backwashing, only the cam 23 is used to drive the clamping plate 29. During the backwashing process, the water inlet pipe 2 will be closed, causing the cam 1 22 to be unable to rotate. At this time, the motor 24 is started to drive the cam 2 23 to rotate, driving the hollow fiber membrane 13 to shake left and right, generating a certain impact force with the water flow, and flushing away the tiny impurities attached to the outer wall of the hollow fiber membrane 13, effectively improving the flushing effect, and when there is a problem with the blade 17, the motor 24 can be started as a substitute.

[0034] The working principle of the present invention is as follows: during the operation of the ultrafiltration system, when the solution from the water inlet pipe 2 enters the filtering chamber 10, the blades 17 are driven to rotate, thereby controlling the rotation of the cam 22 and driving the hollow fiber membrane 13 to move left and right, so that during the filtration process, impurities and blockages attached to the outer wall of the hollow fiber membrane 13 can be shaken off, effectively preventing the filter holes of the hollow fiber membrane 13 from being blocked, and saving energy during long-term filtration. When backwashing is performed, the water inlet pipe 2 is closed, and the motor 24 is started to drive the cam 23 to rotate, controlling the hollow fiber membrane 13 to shake left and right, and effectively improving the backwashing effect.

Claims

1. An albumin polypeptide ultrafiltration system for enhancing immune activity, characterized in that: It comprises a box body (1), a filter assembly, a water inlet pipe (2), a backwash pipe (5), a water outlet pipe (3), a filtrate pipe (4) and a shaking assembly; The filter assembly includes a plurality of hollow fiber membranes (13), and a mounting plate 1 (14) and a mounting plate 2 (15) are respectively provided at both ends of the hollow fiber membrane (13), and a plurality of through holes are provided on the mounting plate 1 (14), and one end of the hollow fiber membrane (13) is connected to the through hole, and the mounting plate 2 (15) blocks the other end of the fiber membrane, and the mounting plate 1 (14) and the mounting plate 2 (15) are fixedly connected by a connecting rod (16); The water inlet pipe (2) is connected to one end of the box (1), and the water outlet pipe (3) is connected to the other end of the box (1). The solution to be filtered is passed into the box (1), and the albumin polypeptide solution is filtered out through the filter holes of the hollow fiber membrane (13); The filtered filtrate is collected through the filtrate pipe (4), and the side of the filtrate pipe (4) is connected to the backwash pipe (5); The shaking assembly drives the hollow fiber membrane (13) to move left and right; The shaking assembly includes a cam 1 (22) and a clamping plate (29), the side of the mounting plate 2 (15) away from the hollow fiber membrane (13) is fixedly connected to the clamping plate (29), the side of the cam 1 (22) is in contact with the clamping plate (29), two partitions (8) are provided in the box body (1), the partitions (8) are arranged up and down, and a mounting groove (30) is provided in the partition (8), the mounting plate 1 (14) and the mounting plate 2 (15) are respectively located in the mounting grooves (30) of the upper and lower partitions (8), and a sliding groove (31) is provided on the side of the mounting groove (30), the mounting plate 1 (14) and the mounting plate 2 (15) are both located in the sliding groove (31), and a spring (32) is provided at one end of the sliding groove (31), and the two springs (32) respectively exert a certain thrust on the mounting plate 1 (14) and the mounting plate 2 (15), and the cam 1 (22) is connected to a driving mechanism; The driving mechanism comprises a blade (17), a rotor (18), a bevel gear 1 (19), a bevel gear 2 (20) and a rotating shaft (21); the blade (17) is located in the water inlet pipe (2), and the water inlet pipe (2) has a right-angle turn position; one end of the rotor (18) is fixedly connected to the blade (17), and the other end of the rotor (18) passes through the right-angle turn position and is fixedly connected to the bevel gear 1 (19); the bevel gear 2 (20) is meshed with the bevel gear 1 (19); one end of the rotating shaft (21) is fixedly connected to the bevel gear 2 (20), and the other end passes through the box (1) and is fixedly connected to the cam 1 (22).

2. The albumin polypeptide ultrafiltration system for enhancing immune activity according to claim 1, characterized in that: A separation cover (25) is fixedly connected to the first mounting plate (14). The separation cover (25) is an inverted bowl-shaped structure. The separation cover (25) wraps all the through holes. The separation cover (25) is connected to the filtrate tube (4) via a bellows (26).

3. The albumin polypeptide ultrafiltration system for enhancing immune activity according to claim 1, characterized in that: The partition (8) located at the top of the box body (1) is provided with a plurality of water holes (12), and the two partitions (8) divide the interior of the box body (1) into three spaces: a water outlet chamber (11), a filter chamber (10) and a shaking chamber (9), the water inlet pipe (2) is connected to the filter chamber (10), and the hollow fiber membrane (13) is located in the filter chamber (10), the shaking assembly is located in the shaking chamber (9), the water outlet pipe (3) is connected to the water outlet chamber (11), and the water holes (12) connect the water outlet chamber (11) and the filter chamber (10).

4. The albumin polypeptide ultrafiltration system for enhancing immune activity according to claim 1, characterized in that: The upper and lower surfaces of the mounting plate 1 (14) and the mounting plate 2 (15) are both provided with sealing grooves, and the sealing grooves surround the mounting plate 1 (14) or the mounting plate 2 (15). A sealing ring (33) is provided in the sealing groove, and the sealing ring (33) is tightly attached to the slide groove (31).

5. The albumin polypeptide ultrafiltration system for enhancing immune activity according to claim 3, characterized in that: A drain pipe (27) is provided on the bottom side wall of the shaking chamber (9), and a valve (28) is provided on the drain pipe (27).

6. The albumin polypeptide ultrafiltration system for enhancing immune activity according to claim 3, characterized in that: The filtrate pipe (4) and the backwash pipe (5) are installed with valve two (7) and valve three (6).

7. The albumin polypeptide ultrafiltration system for enhancing immune activity according to claim 3, characterized in that: A motor (24) is installed at the bottom of the box body (1), and the output shaft of the motor (24) penetrates into the shaking chamber (9), and the output shaft of the motor (24) is fixedly connected to the cam 2 (23). The cam 1 (22) and the cam 2 (23) do not affect each other, and both drive the clamping plate (29). When the water inlet pipe (2) is filtered, only the cam 1 (22) is used to drive the clamping plate (29), and the protruding end of the cam 2 (23) is away from the clamping plate (29). When backwashing, only the cam 2 (23) is used to drive the clamping plate (29).

Citation Information

Patent Citations

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    CN201728065U

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