Cellular chemical disruption reaction holding device

Abstract

The present disclosure provides a cell chemical disruption reaction holding device, comprising: a disposable reaction holding tube through which a material passes and which provides a space required for the material to complete a cell chemical disruption reaction; a main frame carrying the disposable reaction holding tube; a fixing device provided on the main frame, through which the disposable reaction holding tube is detachably fixed on the main frame; and a supporting device provided at the bottom of the main frame to enable the cell chemical disruption reaction holding device to stand stably on a plane. The present disclosure is flexibly applied to various types of cell chemical disruption devices by providing a switchable disposable reaction holding tube, and the reaction holding tube is disposable, thus eliminating the need for cleaning and sterilization.

Description

Technical Field

[0001] This disclosure relates to the field of biological cell chemical disruption equipment technology, and in particular to a cell chemical disruption reaction holding device. Background Technology

[0002] To ensure that intracellular substances are fully chemically broken down and released, the cell chemical breakdown process needs to be maintained in a state of breakdown for a period of time before subsequent operations are carried out.

[0003] Existing cell disruption equipment includes a cell chemical disruption reaction holding tube. By allowing materials to flow within the rigid reaction holding tube for a period of time, intracellular substances are released. However, existing rigid reaction holding tubes are not easy to disassemble and replace, cannot meet different cell disruption needs, and are inconvenient to clean. Summary of the Invention

[0004] In view of this, the purpose of this disclosure is to provide a disposable cell chemical disruption reaction holding device that is easy to disassemble and replace without cleaning, and can be flexibly applied to a variety of different types of cell chemical disruption devices.

[0005] To achieve the above objectives, this disclosure provides a device for maintaining a cell chemical disruption reaction, comprising:

[0006] A single-use reaction holding tube that allows material to pass through and provides the space needed for the material to complete the cytochemical disruption reaction;

[0007] The main frame supports the disposable reaction holding tube; a fixing device is provided on the main frame, through which the disposable reaction holding tube can be detachably fixed to the main frame;

[0008] A support device is installed at the bottom of the main frame to keep the cytochemical disruption reaction device stable on the plane it is on.

[0009] Furthermore, the disposable reaction holding tube includes at least one of disposable flexible tubing and rigid tubing.

[0010] Furthermore, the fixing device includes several placement slots for storing disposable reaction holding tubes; the placement slots include spaced-apart arc-shaped buckles that fix the disposable reaction holding tubes in the placement slots.

[0011] Furthermore, the main frame includes a first frame, a second frame, and a connecting device disposed between the first frame and the second frame; the main frame is capable of switching back and forth between a folded state and an unfolded state; in the folded state, the first frame and the second frame are folded based on the connecting device; in the unfolded state, the first frame and the second frame are coplanar.

[0012] Furthermore, at least one set of openable door panels are respectively provided on the outer surfaces of the first frame and the second frame; at least one set of liquid inlets and one set of liquid outlets of the cell chemical disruption reaction holding device are provided on the surface of the door panels.

[0013] Furthermore, the disposable reaction holding tube includes a disposable flexible tubing; the cytochemical disruption reaction holding device is provided with at least one set of flexible tubing clamps, which are movably mounted on the fixing device.

[0014] Furthermore, the main frame also includes a limiting structure; the limiting structure includes a limiting hinge disposed between the first frame and the second frame, which enables the main frame to remain in a folded or unfolded state.

[0015] Furthermore, the support device includes a first support member pivotally connected to the first frame and a second support member pivotally connected to the second frame.

[0016] Furthermore, the cell chemical disruption reaction holding device also includes a moving device; the moving device is located at the lower end of the support device.

[0017] Furthermore, the mobility device includes casters; the casters can switch between caster and kick, the casters can move the cytochemical disruption reaction holding device, and the kick can fix the cytochemical disruption reaction holding device.

[0018] Compared with the prior art, the technical solution provided in this disclosure can be flexibly applied to a variety of different types of cell chemical disruption devices by setting a switchable disposable reaction holding tube. The disposable reaction holding tube is a disposable pipeline that can be quickly switched according to reaction needs without cleaning. Attached Figure Description

[0019] To more clearly illustrate the technical solutions in this disclosure or related technologies, the accompanying drawings used in the description of the embodiments or related technologies will be briefly introduced below. Obviously, the accompanying drawings described below are only embodiments of this disclosure. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0020] Figure 1 A three-dimensional schematic diagram of the folded state of the cell chemical disruption reaction holding device provided in the embodiments of this disclosure;

[0021] Figure 2 Internal structural diagram of the folded state of the cell chemical disruption reaction holding device provided in the embodiments of this disclosure;

[0022] Figure 3 for Figure 2 The main view;

[0023] Figure 4 A side view of the folded state of the cell chemical disruption reaction holding device provided in an embodiment of this disclosure;

[0024] Figure 5 A top view of the placement slot provided in an embodiment of this disclosure;

[0025] Figure 6 for Figure 5 Sectional view at point AA;

[0026] Figure 7 A three-dimensional schematic diagram of the unfolded state of the cell chemical disruption reaction holding device provided in the embodiments of this disclosure;

[0027] Figure 8 This is an internal structural diagram of the cell chemical disruption reaction holding device provided in the embodiments of this disclosure, in its deployed state. Detailed Implementation

[0028] To make the objectives, technical solutions, and advantages of this disclosure clearer, the following detailed description is provided in conjunction with specific embodiments and the accompanying drawings.

[0029] It should be noted that, unless otherwise defined, the technical or scientific terms used in the embodiments of this disclosure should have the ordinary meaning understood by one of ordinary skill in the art to which this disclosure pertains. The terms "first," "second," and similar terms used in the embodiments of this disclosure do not indicate any order, quantity, or importance, but are merely used to distinguish different components. Terms such as "comprising" or "including" mean that the element or object preceding the word encompasses the elements or objects listed following the word and their equivalents, without excluding other elements or objects. Terms such as "connected" or "linked" are not limited to physical or mechanical connections, but can include electrical connections, whether direct or indirect. Terms such as "upper," "lower," "left," and "right" are used only to indicate relative positional relationships; when the absolute position of the described object changes, the relative positional relationship may also change accordingly.

[0030] Cell disruption time plays a decisive role in the yield of intracellular products; therefore, it is essential to incorporate a cell disruption device to maintain the cytochemical disruption reaction in the cell disruption equipment used in product manufacturing. To improve cell disruption efficiency, large-scale production is often required, ensuring the cell disruption equipment operates at a continuous high flow rate. To accommodate this continuous high flow rate and guarantee sufficient cytochemical disruption reaction time, existing cytochemical disruption reaction maintenance devices often employ helical rigid tubing to complete the cytochemical disruption process. For details, please refer to the prior Chinese patent, application number: CN202210349743.4, entitled: A Continuous Alkaline Lysis System for Plasmid Preparation and a Method for Plasmid Preparation.

[0031] To meet varying production conditions, the cytochemical disruption reaction time needs to be adjusted in real time. However, existing rigid pipes, being fixedly connected to the cell disruption equipment and unable to move, cannot provide different cytochemical disruption reaction times for different batches of materials. Therefore, they lack flexibility, are applicable only to a limited range of scenarios, and cannot meet the needs of different production conditions.

[0032] Cellular chemical disruption reaction holding devices generally need to be placed in clean areas and have certain requirements for environmental cleanliness. During the disruption process, the disrupted cells also need to be in a clean environment to avoid external environmental contamination. However, existing rigid tubes use a spiral structure, and there are indentations or gaps between the spiral tubes, which easily accumulate dirt that is difficult to clean and cannot be disassembled for cleaning, making cleaning inconvenient.

[0033] Therefore, this disclosure provides a cell chemical disruption reaction holding device, which, together with a disposable reaction holding tube, is easy to disassemble and requires no cleaning, and can be flexibly applied to various types of cell chemical disruption devices. For example... Figure 1 The diagram illustrates an embodiment of a cytochemical disruption reaction holding device disclosed herein, comprising a disposable reaction holding tube (not shown), a main frame 100, and a support device. The disposable reaction holding tube is disposed within the main frame 100, providing space for material passage and the completion of the cytochemical disruption reaction. The main frame 100 is a plate-shaped rectangular frame used to support the disposable reaction holding tube. A fixing device is provided on the main frame 100, allowing the disposable reaction holding tube to be detachably fixed to the main frame 100. The specific structure of the fixing device is described below. The support device is located at the bottom of the main frame 100, ensuring the cytochemical disruption reaction holding device stands stably on its surface. The surface refers to the actual working surface of the cytochemical disruption reaction holding device, such as the ground or a tabletop.

[0034] Disposable reaction holding tubing is preferably made of flexible tubing, which is easier to disassemble. Disposable sanitary silicone tubing can be selected; it can be directly replaced after use without cleaning, making it convenient to use. Alternatively, disposable reaction holding tubing can also be made of rigid tubing, which offers greater structural stability. Rigid tubing can be made of materials such as metal or plastic. Optionally, disposable reaction holding tubing can be used in conjunction with both flexible and rigid tubing as needed to expand the applicability of the cell disruption reaction holding device. The type, length, and diameter of the disposable reaction holding tubing should be selected in advance according to the requirements of the cell disruption equipment.

[0035] This disclosure uses a cell disruption device as an example; it is understood that the scope of protection of this disclosure is not limited thereto.

[0036] The fixing device includes a flat plate 210, with several placement slots 200 on the upper surface of the plate 210 for storing disposable reaction holding tubes. The plate 210 is preferably a plastic plate. The placement slots 200 are arranged in parallel. The disposable reaction holding tubes are preferably arranged in an S-shape (not shown in the figure) to improve space utilization and facilitate subsequent maintenance and management. The disposable reaction holding tubes are detachably fixed within the placement slots 200. During the cell disruption reaction, the disposable reaction holding tubes are fixed within the placement slots 200. Detachable fixing means that the disposable reaction holding tubes can be inserted into or removed from the placement slots 200, facilitating disassembly and installation, allowing for quick switching between different specifications of disposable reaction holding tubes, suitable for rapid switching between different batches of cell disruption equipment, and flexibly applicable to various cell disruption reaction scenarios.

[0037] Specifically, the placement slot 200 includes rectangular slots 201 and arc-shaped slots 202 spaced apart. The top of the arc-shaped slot 202 is a rectangular opening, and the bottom is arc-shaped. Arc-shaped clips 203 are provided on both sides of the arc-shaped slot 202 to secure the disposable reaction holding tube, such as... Figure 5 and Figure 6 As shown. Optionally, the arc-shaped clip 203 can also be a conventional shape such as rectangular, columnar, or strip. The diameter of the arc-shaped groove 202 is smaller than the width of the rectangular groove 201. The disposable reaction holding tube is interference-fitted with the arc-shaped clip 203, and the width of the rectangular groove 201 is larger than the diameter of the disposable reaction holding tube, allowing for convenient locking of the disposable reaction holding tube within the placement groove 200. The rectangular groove 201, arc-shaped groove 202, and arc-shaped clip 203 achieve a detachable fixing function. Of course, other conventional detachable fixing methods can be selected as needed, such as sliding rails, screws, bolts, etc. Optionally, the placement groove 200 can be adapted to accommodate other shapes of the disposable reaction holding tube as needed. Optionally, the placement groove 200 can only include the spaced-apart arc-shaped clips 203 to reduce processing difficulty and construction costs.

[0038] The main frame 100 is made of metal sheet with a smooth outer surface, making it resistant to contamination and easy to clean. For example, it can be made of stainless steel sheet using sheet metal processing. Optionally, the main frame 100 can also be made of plastic sheet. The main frame 100 includes a first frame 110, a second frame 120, and a connecting device 130 disposed between the first frame 110 and the second frame 120. The main frame 100 can switch between a folded state and an unfolded state. In the folded state, the main frame 100 is preferably placed vertically, with the first frame 110 and the second frame 120 folded based on the connecting device 130. Figure 1As shown. Correspondingly, the disposable reaction holding tubes are vertically distributed in the first frame 110 and the second frame 120. In the unfolded state, the main frame 100 is preferably placed horizontally, and the first frame 110 and the second frame 120 are coplanar, as shown. Figure 7 As shown. Correspondingly, the disposable reaction holding tubes are horizontally distributed in the first frame 110 and the second frame 120. Optionally, the placement angle of the main frame 100 can be selected in the folded and unfolded states as needed to adapt to the specific operation of the cytochemical disruption reaction.

[0039] It should be noted that the main frame 100 of this disclosure can perform the cytochemical disruption reaction process in both the folded and unfolded states. The unfolded state, being horizontally placed, facilitates the operator's installation of disposable reaction holding tubes and avoids the influence of gravity on the cytochemical disruption reaction process; therefore, the unfolded state is preferred for this process. In the folded state, because the first frame 110 and the second frame 120 are folded vertically together, the footprint of the main frame 100 is reduced, and it is easier to store in a warehouse; therefore, the folded state is preferred for storage.

[0040] Preferably, the connecting device 130 consists of two sets of hinges symmetrically arranged between the first frame 110 and the second frame 120, capable of driving the first frame 110 and the second frame 120 to rotate relative to each other by 180 degrees. Alternatively, each set of hinges can drive the first frame 110 and the second frame 120 to rotate relative to each other by 90 degrees. Optionally, the connecting device 130 can be selected from other conventional connecting devices 130 as needed, such as pivots or hinges. Optionally, those skilled in the art can configure the connecting device 130 to drive the first frame 110 and the second frame 120 to rotate relative to each other by more than 180 degrees or by less than 90 degrees, as needed.

[0041] Several support plates 140 are also fixedly installed within the first frame 110 and the second frame 120. The support plates 140 are used to support the flat plate 210, and the flat plate 210 can slide relative to the support plates 140. Optionally, the flat plate 210 can also be fixedly installed on the support plates 140 as needed, preferably by screws and bolts.

[0042] The outer surfaces of the first frame 110 and the second frame 120 are each provided with two sets of openable door panels 160, for a total of four sets of door panels 160. When in the unfolded state, the four sets of door panels 160 are arranged in a rectangular pattern, as shown below. Figure 7 As shown. When in the folded state, the four door panels (160° each) are arranged back-to-back in pairs, as shown. Figure 1As shown. The outer ends of each set of door panels 160 are hinged to the first frame 110 and the second frame 120 via two hinges 300. The four sets of door panels 160 form two sets of double-leaf doors. Preferably, the door panels 160 can rotate 180 degrees relative to the first frame 110 and the second frame 120. Of course, the door panels 160 can rotate to other angles relative to the first frame 110 and the second frame 120, and this disclosure does not limit this. Optionally, one or more sets of door panels 160 can be opened and closed on the outer surfaces of the first frame 110 and the second frame 120 as needed.

[0043] Each set of door panels 160 has an inlet 400 and an outlet 500 at the edge of its outer surface, respectively, for a cell disruption reaction holding device. Disposable reaction holding tubes pass through the inlet 400 and outlet 500 at both ends, connecting to the upstream and downstream devices of the cell disruption equipment. When connecting the disposable reaction holding tube, either inlet 400 or outlet 500 can be selected as needed. The inlet 400 and outlet 500 of this disclosure are of the same specification and can be interchanged. The connection between the disposable reaction holding tube and the cell disruption equipment is a detachable connection, such as a clamp or buckle. Optionally, one or more sets of inlets 400 and outlets 500 can be provided on the outer surface of the door panel 160 or the main frame 100 as needed, and either inlet 400 or outlet 500 can be selected to connect to the disposable reaction holding tube as required.

[0044] Furthermore, each door panel 160 is equipped with a set of permanent magnets (not shown in the figure) on the side away from the hinge 300. Correspondingly, the main frame 100 is fitted with another set of permanent magnets (not shown in the figure) at the contact end with the door panel 160. When the door panel 160 is closed, the two sets of permanent magnets attract each other, forming a fixed structure when the door panel 160 is closed. Optionally, other conventional fixed structures for the closed door panel 160 can be used, such as bolts, door locks, etc.

[0045] The support device includes several connecting rods 600, a first support member 171 pivotally connected to the first frame 110, and a second support member 172 pivotally connected to the second frame 120. The first support member 171 and the second support member 172 are respectively fixedly mounted on both sides of the support plate 140. The connecting rods 600 are L-shaped hollow square tubes with vertical upper ends, pivotally connected to the first support member 171 via a first pivot part 181, and pivotally connected to the second support member 172 via a second pivot part 182. The lower ends of the connecting rods 600 are horizontal and are fixedly connected to a moving device via screws and bolts. Figure 4As shown. Optionally, conventional fixing methods such as welding can also be used for the fixed connection. When in the folded state, the four sets of connecting rods 600 are arranged in pairs facing away from each other. When switching from the folded state to the unfolded state, the first frame 110 and the second frame 120 rotate around the connecting device 130, rotating from vertical to horizontal. At the same time, the lower end of the main frame 100 rotates around the connecting rods 600, so that the four sets of connecting rods 600 are distributed at the four corners of the main frame 100 when unfolded, forming a stable desktop structure.

[0046] For example, the cell chemical disruption reaction holding device also includes a moving device. The moving device is located at the lower end of the connecting rod 600. Optionally, multiple sets of connecting rods 600 can be provided at the lower end of the main frame 100 to connect with the moving device, such as three sets of connecting rods 600, six sets of connecting rods 600, etc., with at least one moving device provided at the lower end of each set of connecting rods 600.

[0047] Furthermore, the moving device includes casters 700, which can switch between being casters and kick-type. The casters move the cytochemical disruption reaction holding device, while the kick-type device secures it. In the folded state, the cytochemical disruption reaction holding device can be moved by the moving device, at which point the casters 700 switch to casters, facilitating the transport of the device. In the unfolded state or when storing the device, the casters 700 switch to kick-type to secure it, facilitating the cell disruption process and storage. The casters 700 disclosed herein are existing moving structures, and their specific structure will not be described in detail here. Optionally, the moving device can be equipped with other conventional moving devices as needed, such as motor-driven and braked wheels.

[0048] For example, when the disposable reaction holding tube includes flexible tubing, the cytochemical disruption reaction holding device is equipped with four sets of flexible tubing clamps 800. The four sets of flexible tubing clamps 800 are distributed in pairs within the first frame 110 and the second frame 120, as shown below. Figure 2-3 As shown. The hose clamping plate 800 is movably mounted on the upper end of the placement tank 200. After the flexible pipe is installed in the placement tank 200, the hose clamping plate 800 is moved above the flexible pipe and presses it down, thereby preventing material from entering the flexible pipe and impacting it, causing it to fall out of the placement tank 200. Optionally, one or more sets of hose clamping plates 800 can be installed in the first frame 110 and the second frame 120 as needed.

[0049] Specifically, the flexible hose clamping plate 800 is movable by sliding, and the first frame 110 and the second frame 120 are provided with sliding grooves on both sides to accommodate the flexible hose clamping plate 800. The four sets of flexible hose clamping plates 800 can slide within the sliding grooves in the first frame 110 and the second frame 120, allowing the flexible clamping plate 800 to cover any position of the flexible pipe. The flexible hose clamping plate 800 also includes a handle 801, which the operator uses to move the flexible hose clamping plate 800 for convenient use. The sliding direction of the flexible hose clamping plate 800 is consistent with the placement direction of the flexible pipe in the placement groove 200. Optionally, the movable method of the flexible hose clamping plate 800 can be selected according to other conventional movement methods as needed. For example, multiple sets of flexible hose clamping plates 800 can be hinged to both sides of the first frame 110 and the second frame 120 respectively, allowing free rotation to press down on the flexible pipe at different positions.

[0050] For example, the main frame 100 also includes a rectangular plate 150 with rounded corners. The rectangular plate 150 is detachably connected to the outer surface of the main frame 100 to seal the inlet 400 and the outlet 500. The detachable connection is preferably made of screws or bolts. When the inlet 400 and the outlet 500 are not needed or are not used, the rectangular plate 150 seals the inlet 400 and the outlet 500, preventing external dust from entering the interior of the main frame 100 and contaminating the internal environment of the main frame 100.

[0051] For example, the main frame 100 also includes a limiting structure. The limiting structure includes a limiting hinge disposed between the first frame 110 and the second frame 120, enabling the main frame 100 to remain in a folded or unfolded state. Preferably, the connecting device 130 serves as the limiting hinge. When the main frame 100 is in a folded or unfolded state, the limiting hinge restricts the position of the first frame 110 and the second frame 120, preventing them from continuing to rotate around the connecting device 130, thereby keeping the main frame 100 in a folded or unfolded state. This prevents the main frame 100 from automatically switching states under external force during storage or cell disruption, improving the stability of the cell disruption reaction holding device. Optionally, the first pivot portion 181 and / or the second pivot portion 182 serve as the limiting hinge.

[0052] The cell disruption device operates as follows: The type, diameter, and length of the disposable reaction holding tube are selected in advance according to the requirements of the cell disruption equipment. The cell disruption reaction holding device is switched to the deployed state, the moving device is fixed, and the operator stands to operate. When the disposable reaction holding tube includes a flexible tube, the selected flexible tube is fixed in an S-shaped arrangement within the placement groove 200. The flexible tube is pressed down by moving the flexible tube pressure plate 800 using the handle 801.

[0053] The disposable reaction holding tube extends from the inlet 400 and the outlet 500 at both ends and is connected to the cell disruption equipment. After the upstream process of the cell disruption equipment is completed, the material is fed into the disposable reaction holding tube from the inlet 400. After flowing in the disposable reaction holding tube for a period of time, it returns to the cell disruption equipment from the outlet 500 for further processing.

[0054] After use, the cell chemical disruption reaction holding device is separated from the cell disruption equipment, the disposable reaction holding tube is disassembled, and the cell chemical disruption reaction holding device is switched to a folded state for storage.

[0055] The above embodiments of this disclosure achieve the following technical effects: By setting a switchable disposable reaction holding tube, it can be flexibly applied to various types of cell disruption devices. Disassembly is achieved simply by removing the disposable reaction holding tube from the placement slot 200; installation is achieved by inserting the disposable reaction holding tube into the placement slot 200, facilitating switching and convenient use. The main frame 100 can perform the cell disruption process in both folded and unfolded states. In the unfolded state, because it is placed horizontally, it is convenient for the operator to install the disposable reaction holding tube. In the folded state, the footprint of the main frame 100 is reduced, and it is convenient for storage in a warehouse. The disposable reaction holding tube is for single use only and can be directly disassembled and replaced after use without cleaning, facilitating the use of cell disruption equipment. The main frame 100 can be used with both flexible and rigid tubing, increasing the applicability of the cell disruption reaction holding device.

[0056] Those skilled in the art should understand that the discussion of any of the above embodiments is merely exemplary and is not intended to imply that the scope of this disclosure (including the claims) is limited to these examples; many substitutions, modifications and variations of these embodiments will be apparent to those skilled in the art based on the foregoing description, and for the sake of brevity they are not provided in detail.

[0057] This disclosure is intended to cover all such substitutions, modifications, and variations that fall within the broad scope of the appended claims. Therefore, any omissions, modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this disclosure should be included within the scope of protection of this disclosure.

Claims

1. A cell chemical disruption reaction holding device characterized by comprising: include: A single-use reaction holding tube that allows material to pass through and provides the space needed for the material to complete the cytochemical disruption reaction; The main frame supports the disposable reaction holding tube; a fixing device is provided on the main frame, and the disposable reaction holding tube is detachably fixed to the main frame through the fixing device. A support device is provided at the bottom of the main frame to ensure that the cell chemical disruption reaction device is stably positioned on the plane in which it is located. The main frame includes a first frame, a second frame, and a connecting device disposed between the first frame and the second frame; the main frame is capable of switching between a folded state and an unfolded state; in the folded state, the first frame and the second frame are folded based on the connecting device; In the unfolded state, the first frame and the second frame are coplanar; The outer surfaces of the first frame and the second frame are respectively provided with at least one set of openable door panels; the surface of the door panel is provided with at least one set of liquid inlet and one set of liquid outlet of the cell chemical disruption reaction holding device; The disposable reaction holding tube includes a disposable flexible tube; the cytochemical disruption reaction holding device is provided with at least one set of flexible tube clamps, which are movably mounted on the fixing device.

2. The cell chemical disruption reaction holding apparatus according to claim 1, characterized by The disposable reaction holding tube includes at least one of disposable flexible tubing and rigid tubing.

3. The cell chemical disruption reaction holding apparatus according to claim 1, characterized by The fixing device includes several placement slots for receiving the disposable reaction holding tube; each placement slot includes spaced arc-shaped buckles that fix the disposable reaction holding tube in the placement slot.

4. The cell chemical disruption reaction holding apparatus according to claim 1, characterized by The main frame also includes a limiting structure; the limiting structure includes a limiting hinge disposed between the first frame and the second frame, which enables the main frame to be kept in a folded or unfolded state.

5. The cell chemical disruption reaction holding apparatus according to claim 1, wherein The support device includes a first support member pivotally connected to the first frame and a second support member pivotally connected to the second frame.

6. The cell chemical disruption reaction holding apparatus according to claim 1, wherein The cell chemical disruption reaction holding device also includes a moving device; the moving device is disposed at the lower end of the support device.

7. The cell chemical disruption reaction holding apparatus according to claim 6, characterized by The moving device includes casters; the casters can switch between caster and kick, the casters can move the cell chemical disruption reaction holding device, and the kick can fix the cell chemical disruption reaction holding device.

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