Sterilization apparatus for a vaccinia virus production plant

Abstract

The application relates to the field of vaccinia virus production, and provides a sterilization equipment for a vaccinia virus production workshop, which comprises a main feeding conveying belt, the rear side of the main feeding conveying belt is provided with an automatic control console, the upper surface of the main feeding conveying belt is provided with a tray mechanism, the right side of the main feeding conveying belt is provided with a cleaning mechanism, the right side of the cleaning mechanism is provided with a stacking mechanism, the right side of the stacking mechanism is provided with a steam sterilization structure, and the steam sterilization structure comprises a box mechanism, a steam mechanism and a pushing mechanism. The right side of the pushing mechanism is provided with a microwave sterilization mechanism. The automatic control console controls the cleaning mechanism, the stacking mechanism and the microwave sterilization mechanism and cooperates with the tray mechanism, so that the purpose of automatically sterilizing a batch of culture containers is achieved, the processing efficiency is improved through the automation of the equipment, and the labor burden of workers is reduced.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of vaccinia virus production, in particular to a sterilization equipment for vaccinia virus production workshop. BACKGROUND

[0002] Poxvirus is the largest class of DNA viruses, including various types: such as vaccinia virus, smallpox virus, cowpox virus and monkeypox virus, etc., vaccinia virus is often used as vaccine strain for the prevention and immunization of various diseases, because vaccinia virus has the characteristics of wide host range, many non-essential genes, high conservation, large capacity of foreign genes, etc., vaccinia virus as a vaccine carrier has great value for the development of new infectious disease vaccine carriers.

[0003] In the production process of vaccinia virus, vaccinia virus needs to be placed in a suitable cell culture system for propagation, and suitable cells are cultured and propagated under sterile conditions to provide nutrients and environment required for virus growth, but the culture container needs to be sterilized before use to prevent bacteria or other microorganisms from causing contamination to the culture environment, in the prior art, the culture container is usually placed into a sterilization equipment for sterilization by manual operation, but this method is only suitable for small-scale laboratory cultivation, in large-scale production, the efficiency of manual sterilization using equipment is low, and the labor intensity is high, and frequent manual handling can easily cause contamination and damage to the culture container, affecting the production quality of vaccinia virus. SUMMARY

[0004] In view of the defects of the prior art, the present application provides a sterilization equipment for vaccinia virus production workshop, which solves the problems of low efficiency of manual sterilization using equipment, high labor intensity, and frequent manual handling which can easily cause contamination and damage to the culture container, affecting the production quality of vaccinia virus.

[0005] To achieve the above purpose, the present application realizes the following technical scheme: the sterilization equipment for vaccinia virus production workshop comprises a main feeding conveyor belt, first sensors are arranged on the front and rear sides of the main feeding conveyor belt, an automatic control console is arranged on the rear side of the main feeding conveyor belt, a tray mechanism is arranged on the upper surface of the main feeding conveyor belt, the tray mechanism comprises a tray body and a culture container, the tray mechanism can protect and fix the culture container, and the first sensors are electrically connected with the automatic control console.

[0006] The right side of the main feeding conveying belt is provided with a cleaning mechanism, the cleaning mechanism comprises a driving mechanism, a flushing mechanism and a jet mechanism, the driving mechanism comprises a rotating shaft and a conveying roller, the conveying roller can smoothly convey the tray mechanism to the inside of the cleaning mechanism, and the flushing mechanism and the jet mechanism in the cleaning mechanism can clean the culture container on the tray mechanism, the flushing mechanism comprises a high-pressure nozzle and a water collecting bucket, the upper and lower surfaces of the culture container can be cleaned by the oppositely arranged high-pressure nozzles, and the jet mechanism comprises an air inlet pipe and a jet port, and the culture container can be jet cleaned by the oppositely arranged jet ports.

[0007] The right side of the cleaning mechanism is provided with a stacking mechanism, and the right side of the stacking mechanism is provided with a steam sterilization structure. The stacking mechanism can stack the tray body in multiple layers, so that the culture containers can be sent into the subsequent steam sterilization structure in batches for sterilization treatment. The steam sterilization structure comprises a box mechanism, a steam mechanism and a pushing mechanism. The right side of the pushing mechanism is provided with a microwave sterilization mechanism.

[0008] Preferably, the tray mechanism further comprises a sliding groove and a jacking rod. The outer edge of the tray body is provided with a sliding groove. The upper surface of the tray body is fixedly connected with the lower end of a plurality of jacking rods. The lower surface of the tray body is provided with a plurality of fixing grooves. The inner surface of the tray body is fixedly connected with a connecting frame in the middle. The upper surface of the connecting frame is fixedly connected with a plurality of protrusions. The protrusions are slidably connected with the inner surface of the culture container.

[0009] Preferably, the driving mechanism further comprises a driving servo motor and a steering speed reducer. The front and rear sides of the cleaning box are fixedly connected with the adjacent sides of the driving servo motor. The output ends of the driving servo motor are fixedly connected with the input ends of the steering speed reducer. The adjacent sides of the steering speed reducer are fixedly connected with the front and rear sides of the driving servo motor. The output ends of the steering speed reducer are fixedly connected with the outer ends of the rotating shafts on the left and right sides. The rotating shafts penetrate through the front and rear sides of the driving servo motor and are rotatably connected with the cleaning box. The middle parts of the rotating shafts are fixedly connected with transmission gears. The transmission gears are meshingly connected with each other through transmission chains. The adjacent ends of the rotating shafts are fixedly connected with the middle part of the conveying roller. The outer edges of the conveying roller are slidably connected with the inner surface of the sliding groove. The driving servo motor is electrically connected with the automatic control console.

[0010] Preferably, the flushing mechanism further comprises a water inlet pipe and a water distribution pipe. The middle part of the water inlet pipe is fixedly connected with the front and rear ends of the water distribution pipe. The front and rear sides of the water distribution pipe penetrate through the front and rear sides of the cleaning box and are fixedly connected with the cleaning box. The adjacent ends of the water distribution pipe are fixedly connected with the input ends of the high-pressure nozzles. The lower side of the cleaning box is fixedly connected with the upper surface of the water collecting bucket. The middle part of the water collecting bucket is fixedly connected with a drain pipe.

[0011] Preferably, the jet mechanism further comprises a first sliding rail, the middle part of the air inlet pipe penetrates through the front and back sides of the cleaning box and is fixedly connected with the cleaning box, the adjacent ends of the air inlet pipe are fixedly connected with the front and back sides of the air outlet, and the output ends of the air outlet are oppositely arranged.

[0012] Preferably, the stacking mechanism comprises a stacking conveyor belt, a second sensor, the stacking conveyor belt is arranged on the right side of the cleaning box, the middle part of the stacking conveyor belt is fixedly connected with support frames on the front and back sides, the outer sides of the support frames are fixedly connected with a plurality of fixed plates, the middle part of each fixed plate is fixedly connected with an electric push rod, the upper end of each electric push rod is fixedly connected with a connecting plate, the middle part of the connecting plate is slidingly connected with a plurality of sliding guide columns, the adjacent ends of the sliding guide columns are fixedly connected with inclined sliding blocks, the outer sides of the inclined sliding blocks and the sliding guide columns between the adjacent sides of the connecting plate are provided with top springs, the right side of each support frame is provided with a second sensor, the right side of the stacking conveyor belt is provided with a steam sterilization structure, and the stacking conveyor belt, the electric push rod and the second sensor are electrically connected with the automatic control console.

[0013] Preferably, the box mechanism comprises a steam sterilization box and a sliding door, the left and right sides and the lower side of the inside of the steam sterilization box are provided with sliding grooves, the outer surface of the sliding door is slidingly connected with the inner surface of the sliding groove, the left and right ends of the rear side of the sliding door are fixedly connected with sliding blocks, the left and right sides of the steam sterilization box are fixedly connected with side sliding frames, the outer surface of the sliding block is slidingly connected with the inner surface of the side sliding frame, the middle part of the sliding block is threadedly connected with a lifting screw rod, the upper and lower ends of the lifting screw rod are rotatably connected with the inner side of the side sliding frame, the upper end of the lifting servo motor is fixedly connected with the upper end of the lifting screw rod, the left and right inner surfaces of the steam sterilization box are fixedly connected with second sliding rails, the inside of the steam sterilization box is provided with a steel mesh conveyor belt, the lower side of the box mechanism is fixedly connected with a steam mechanism, the front side of the box mechanism is provided with a pushing mechanism, and the lifting servo motor and the steel mesh conveyor belt are electrically connected with the automatic control console.

[0014] Preferably, the steam mechanism comprises a high-temperature steam pipeline, a condensate water collecting hopper and an air exhaust pipe, the lower end of the high-temperature steam pipeline is fixedly connected with the upper side of the steam sterilization box, the front end of the air exhaust pipe is fixedly connected with the rear side of the steam sterilization box, the middle part of the air exhaust pipe is fixedly connected with an air exhaust pipe valve, the upper surface of the condensate water collecting hopper is fixedly connected with the lower surface of the steam sterilization box, the lower surface of the condensate water collecting hopper is fixedly connected with a condensate water discharge pipe, the middle part of the condensate water discharge pipe is fixedly connected with a condensate water discharge valve, and the air exhaust pipe valve and the condensate water discharge valve are electrically connected with the automatic control console.

[0015] Preferably, the pushing mechanism comprises a sub-feeding conveyor belt, a fixed frame, the sub-feeding conveyor belts are arranged on the front side of the steam sterilization box body, the front side of the sub-feeding conveyor belt is provided with a fixed frame, the middle part of the fixed frame is fixedly connected with a plurality of groups of feeding push rods, the rear end of the feeding push rod is fixedly connected with a push plate, the right side of the fixed frame is provided with a third sensor, the adjacent side of the sub-feeding conveyor belt is provided with a connecting conveyor belt, the front side of the connecting conveyor belt is provided with a fourth sensor, and the right side of the pushing mechanism is provided with a microwave sterilization mechanism, and the feeding push rod, the third sensor, the connecting conveyor belt, the fourth sensor and the automatic control console are electrically connected.

[0016] Preferably, the microwave sterilization mechanism comprises a microwave feeding conveyor belt, a fifth sensor, the microwave feeding conveyor belt is arranged on the right side of the pushing mechanism, the fifth sensor is arranged on the front and rear sides of the microwave feeding conveyor belt, the right side of the microwave feeding conveyor belt is provided with a microwave sterilization box, the front and rear sides of the microwave sterilization box are fixedly connected with side gas collectors, the far sides of the side gas collectors are fixedly connected with side air outlet pipes, the right side of the microwave sterilization box is provided with a discharging conveyor belt, and the microwave feeding conveyor belt, the fifth sensor, the microwave sterilization box and the discharging conveyor belt are electrically connected with the automatic control console.

[0017] Working principle: when the equipment is used, first, the culture container is placed on the tray body, and the tray mechanism is placed on the main feeding conveyor belt; through the connection of the automatic control console and the first sensor, whether the tray mechanism is on the main feeding conveyor belt can be sensed through the first sensor, and whether to continue to start the main feeding conveyor belt to send the tray mechanism to the subsequent process is decided according to the situation of the subsequent device; through the cooperation of the internal driving mechanism, the flushing mechanism and the air jet mechanism of the cleaning mechanism, the culture container on the tray mechanism can be cleaned; the driving mechanism moves the tray body stably in the cleaning mechanism through the cooperation of the transmission roller and the sliding groove; the flushing mechanism can flush and clean the upper and lower surfaces of the culture container through the high-pressure nozzle; the air jet mechanism blows and cleans the culture container through the oppositely arranged air jet ports, and the first sliding rail built-in ensures the stable operation of the tray body; after the tray body passes through the inside of the cleaning mechanism and the culture container is cleaned, the tray body is lifted by the stacking mechanism, and is stacked through the structure on the tray body, so that the working efficiency of the subsequent steam sterilization structure and the microwave sterilization mechanism is improved; when the stacked tray body passes through the steam sterilization treatment of the steam sterilization structure and completes the secondary sterilization in the microwave sterilization box, the tray body enters the discharging conveyor belt along the microwave feeding conveyor belt, and then is sent out of the equipment along the discharging conveyor belt to complete the whole sterilization process.

[0018] The present application provides a sterilization equipment for a smallpox virus production workshop.

[0019] 1. This invention achieves automated sterilization of batches of culture containers by controlling the cleaning mechanism, stacking mechanism, and microwave sterilization mechanism through an automatic control console and cooperating with the tray mechanism. The operator only needs to place the culture container on the tray body and then place the tray body on the main feed conveyor belt. The equipment will then automatically and efficiently complete the subsequent sterilization steps. The automation of the sterilization equipment improves processing efficiency and reduces the workload of the operators.

[0020] 2. This invention, through the cooperation of the drive mechanism, rinsing mechanism, and air jet mechanism inside the cleaning mechanism, can efficiently clean the culture containers on the tray mechanism. The drive mechanism moves the tray body smoothly within the cleaning mechanism through the cooperation of the conveyor rollers and the slide, while the rinsing mechanism and the air jet mechanism are used simultaneously to clean the upper and lower surfaces of the culture containers, thereby improving the cleaning efficiency and cleaning effect of the culture containers. Attached Figure Description

[0021] Figure 1 This is a three-dimensional front view of the present invention;

[0022] Figure 2 This is a three-dimensional view of the overall rear side of the present invention;

[0023] Figure 3 This is a three-dimensional schematic diagram showing the details of the tray mechanism of the present invention;

[0024] Figure 4 This is a three-dimensional schematic diagram showing the details of the drive mechanism of the present invention;

[0025] Figure 5 This is a detailed perspective view of the flushing mechanism and the jetting mechanism of the present invention;

[0026] Figure 6 This is a detailed perspective view of the stacking mechanism of the present invention;

[0027] Figure 7 This is a three-dimensional schematic diagram of the overall steam sterilization structure of the present invention;

[0028] Figure 8 This is a detailed perspective view of the box mechanism and steam mechanism of the present invention;

[0029] Figure 9 This is a three-dimensional schematic diagram showing the details of the feeding mechanism of the present invention;

[0030] Figure 10 This is a detailed perspective view of the microwave sterilization mechanism of the present invention.

[0031] Wherein, 1, main feeding conveyor belt; 2, first sensor; 3, automatic control console; 4, tray mechanism; 401, tray body; 402, chute; 403, ejector rod; 404, fixed groove; 405, connecting frame; 406, protruding block; 407, culture container; 5, cleaning mechanism; 6, driving mechanism; 601, driving servo motor; 602, steering reducer; 603, transmission gear; 604, transmission chain; 605, rotating shaft; 606, conveying roller; 607, cleaning box; 7, flushing mechanism; 701, water inlet pipe; 702, water distribution pipe; 703, high-pressure nozzle; 704, water collecting hopper; 705, drain pipe; 8, air jet mechanism; 801, air inlet pipe; 802, air jet; 803, first slide rail; 9, stacking mechanism; 901, stacking conveyor belt; 902, support frame; 903, fixed plate; 904, electric push rod; 905, connecting plate; 906, sliding guide column; 907, top spring; 908, inclined slide block; 909, second sensor; 10, steam sterilization structure; 11, box mechanism; 1101, steam sterilization box; 1102, sliding groove; 1103, sliding door; 1104, sliding block; 1105, side slide frame; 1106, second slide rail; 1107, lifting screw; 1108, lifting servo motor; 1109, steel mesh conveyor belt; 12, steam mechanism; 1201, high-temperature steam pipe; 1202, exhaust pipe; 1203, exhaust pipe valve; 1204, condensate water collecting hopper; 1205, condensate water discharge pipe; 1206, condensate water discharge valve; 13, pushing mechanism; 1301, auxiliary feeding conveyor belt; 1302, fixed frame; 1303, feeding push rod; 1304, push plate; 1305, third sensor; 1306, connecting conveyor belt; 1307, fourth sensor; 14, microwave sterilization mechanism; 1401, microwave feeding conveyor belt; 1402, fifth sensor; 1403, microwave sterilization box; 1404, side air collecting hopper; 1405, side air outlet pipe; 1406, discharging conveyor belt. DETAILED DESCRIPTION

[0032] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the specification of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0033] Embodiment:

[0034] Please refer to the drawings in the specification of the present application Figure 1 - the drawings Figure 10The embodiment of the present application provides the sterilization equipment for the smallpox virus production workshop, including the main feeding conveyor belt 1, the first sensor 2 is arranged on the front and back sides of the main feeding conveyor belt 1, the automatic control console 3 is arranged on the back side of the main feeding conveyor belt 1, the tray mechanism 4 is arranged on the upper surface of the main feeding conveyor belt 1, the tray mechanism 4 includes the tray body 401 and the culture container 407, the tray mechanism 4 can protect and fix the culture container 407, the first sensor 2 is electrically connected with the automatic control console 3, specifically, first, the culture container 407 is placed on the tray body 401, and the tray mechanism 4 is placed on the main feeding conveyor belt 1, through the connection of the automatic control console 3 and the first sensor 2, whether the tray mechanism 4 is on the main feeding conveyor belt 1 can be sensed through the first sensor 2, and whether the main feeding conveyor belt 1 is continuously started to send the tray mechanism 4 to the subsequent process is decided according to the condition of the subsequent device.

[0035] The cleaning mechanism 5 is arranged on the right side of the main feeding conveyor belt 1, the cleaning mechanism 5 includes the driving mechanism 6, the flushing mechanism 7 and the air jet mechanism 8, the driving mechanism 6 includes the rotating shaft 605 and the conveying roller 606, the conveying roller 606 can stably convey the tray mechanism 4 to the inside of the cleaning mechanism 5, so that the flushing mechanism 7 and the air jet mechanism 8 in the cleaning mechanism 5 clean the culture container 407 on the tray mechanism 4, the flushing mechanism 7 includes the high-pressure nozzle 703 and the water collecting hopper 704, the upper and lower surfaces of the culture container 407 can be cleaned by the oppositely arranged high-pressure nozzles 703, the air jet mechanism 8 includes the air inlet pipe 801 and the air jet port 802, the culture container 407 can be cleaned by the oppositely arranged air jet ports 802, specifically, the culture container 407 on the tray mechanism 4 can be cleaned by the cooperation of the driving mechanism 6, the flushing mechanism 7 and the air jet mechanism 8 in the cleaning mechanism 5, the driving mechanism 6 moves the tray body 401 stably in the cleaning mechanism 5 by the cooperation of the conveying roller 606 and the sliding groove 402, wherein the flushing mechanism 7 can clean the upper and lower surfaces of the culture container 407 by the high-pressure nozzles 703, the air jet mechanism 8 blows the culture container 407 by the oppositely arranged air jet ports 802, and the stable operation of the tray body 401 is ensured by the built-in first sliding rail 803.

[0036] The right side of the cleaning mechanism 5 is provided with a stacking mechanism 9, and the right side of the stacking mechanism 9 is provided with a steam sterilization structure 10. The stacking mechanism 9 can stack the tray body 401 in multiple layers, facilitate the batch feeding of the culture container 407 into the subsequent steam sterilization structure 10 for sterilization treatment, and the steam sterilization structure 10 includes a box mechanism 11, a steam mechanism 12, and a pushing mechanism 13. The right side of the pushing mechanism 13 is provided with a microwave sterilization mechanism 14. Specifically, after the tray body 401 passes through the inside of the cleaning mechanism 5 and washes the culture container 407, the tray body 401 is lifted by the stacking mechanism 9 and stacked through the structure on the tray body 401 to improve the working efficiency of the subsequent steam sterilization structure 10 and the microwave sterilization mechanism 14.

[0037] The tray mechanism 4 further includes a sliding groove 402 and a top rod 403. The outer edge of the tray body 401 is provided with a sliding groove 402, and the upper surface of the tray body 401 is fixedly connected with the lower end of a plurality of top rods 403. The lower surface of the tray body 401 is provided with a plurality of fixing grooves 404, and the inner surface of the tray body 401 is fixedly connected with a connecting frame 405 in the middle. The upper surface of the connecting frame 405 is fixedly connected with a plurality of protrusions 406, and the protrusions 406 are slidably connected with the inner surface of the culture container 407.

[0038] Specifically, the sliding groove 402 on the tray body 401 can cooperate with the driving mechanism 6 and the stacking mechanism 9 to realize the functions of movement and stacking. The top rod 403 and the fixing groove 404 on the tray body 401 correspond to each other. When the stacking mechanism 9 stacks the tray body 401, the top rod 403 and the fixing groove 404 can be clamped to ensure that the tray body 401 and the tray body 401 will not slip off. The connecting frame 405 in the tray body 401 can hold the culture container 407, and the protrusions 406 on the connecting frame 405 can clamp the culture container 407 to prevent the culture container 407 from shaking in the tray body 401.

[0039] The driving mechanism 6 further comprises a driving servo motor 601, a steering speed reducer 602, a cleaning box body 607, the front and rear sides of the cleaning box body 607 are fixedly connected with adjacent sides of the driving servo motor 601, output ends of the driving servo motor 601 are fixedly connected with input ends of the steering speed reducer 602, adjacent sides of the steering speed reducer 602 are fixedly connected on the front and rear sides of the driving servo motor 601, output ends of the steering speed reducer 602 are fixedly connected with outer ends of left and right rotating shafts 605, the rotating shafts 605 penetrate through the front and rear sides of the driving servo motor 601 and are rotationally connected with the cleaning box body 607, middle parts of the rotating shafts 605 are fixedly connected with transmission gears 603, the transmission gears 603 are meshingly connected with each other through transmission chains 604, adjacent ends of the rotating shafts 605 are fixedly connected with middle parts of conveying rollers 606, outer edges of the conveying rollers 606 are slidably connected with inner surfaces of the sliding grooves 402, and the driving servo motor 601 is electrically connected with the automatic control console 3.

[0040] Specifically, when the tray body 401 enters the inside of the cleaning box body 607, positions of the sliding grooves 402 on the tray body 401 correspond to the conveying rollers 606, the automatic control console 3 controls the driving servo motor 601 to drive the steering speed reducer 602 to drive the transmission gears 603 to rotate, the transmission gears 603 drive each other through the transmission chains 604, and drive the rotating shafts 605 and the conveying rollers 606 inside to rotate, the rotating shafts 605 and the conveying rollers 606 drive the tray body 401 to move stably to the right along with the rotation of the conveying rollers 606, and the movement of the tray body 401 driven by the conveying rollers 606 enables the upper and lower sides of the culture containers 407 to be cleaned by the flushing mechanism 7 and the air jet mechanism 8 at the same time, and the cleaning effect of the culture containers 407 is improved.

[0041] The flushing mechanism 7 further comprises water inlet pipes 701 and water distribution pipes 702, middle parts of the water inlet pipes 701 are fixedly connected with front and rear ends of the water distribution pipes 702, the front and rear sides of the water distribution pipes 702 penetrate through the front and rear sides of the cleaning box body 607 and are fixedly connected with the cleaning box body 607, adjacent ends of the water distribution pipes 702 are fixedly connected with input ends of high-pressure nozzles 703, the lower side of the cleaning box body 607 is fixedly connected with an upper surface of a water collecting basin 704, and the middle part of the water collecting basin 704 is fixedly connected with a drain pipe 705.

[0042] Specifically, when the tray body 401 moves to the right under the pushing of the conveying rollers 606, the tray body 401 passes between the groups of high-pressure nozzles 703 arranged oppositely, high-pressure water flows into the water distribution pipes 702 through the water inlet pipes 701, and are sprayed out through the high-pressure nozzles 703 to flush and clean the upper and lower sides of the culture containers 407, and dirt on the culture containers 407 is flushed down, and the flushed water flows into the water collecting basin 704 under the action of gravity and is discharged out of the equipment along the drain pipe 705.

[0043] The air jet mechanism 8 further comprises a first slide rail 803, the middle part of the air inlet pipe 801 penetrates through the front and back sides of the cleaning box 607 and is fixedly connected with the cleaning box 607, the adjacent ends of the air inlet pipe 801 are fixedly connected with the front and back sides of the air jet port 802, and the output ends of the air jet port 802 are oppositely arranged.

[0044] Specifically, when the tray body 401 moves to the right under the pushing of the conveying roller 606, the first slide rail 803 can support the lower surface of the tray body 401, so as to ensure the stable operation of the tray body 401. After the tray body 401 passes through the washing mechanism 7, the tray body 401 will pass between the oppositely arranged air jet ports 802 along the first slide rail 803. High-pressure air enters the air jet port 802 through the air inlet pipe 801 and is sprayed out along the air jet port 802, so as to spray and clean the upper and lower surfaces of the culture container 407 on the tray body 401. At the same time, the culture container 407 can be blown to remove most of the water on the culture container 407 as much as possible, so as to avoid affecting the subsequent sterilization process.

[0045] The stacking mechanism 9 comprises a stacking conveyor belt 901 and a second sensor 909. The stacking conveyor belt 901 is arranged on the right side of the cleaning box 607. The middle part of the front and back sides of the stacking conveyor belt 901 is fixedly connected with a support frame 902. The outer side of the support frame 902 is fixedly connected with a plurality of fixed plates 903. The middle part of the fixed plate 903 is fixedly connected with an electric push rod 904. The upper end of the electric push rod 904 is fixedly connected with a connecting plate 905. The middle part of the connecting plate 905 is slidably connected with a plurality of sliding guide columns 906. The adjacent ends of the sliding guide columns 906 are fixedly connected with an inclined sliding block 908. The outer side of the inclined sliding block 908 and the sliding guide columns 906 between the adjacent sides of the connecting plate 905 are provided with a top spring 907. The right side of the support frame 902 is provided with the second sensor 909. The right side of the stacking conveyor belt 901 is provided with the steam sterilization structure 10. The stacking conveyor belt 901, the electric push rod 904 and the second sensor 909 are electrically connected with the automatic control console 3.

[0046] Specifically, when the tray body 401 is cleaned by the washing mechanism 7 and the air jet mechanism 8, it is pushed out of the inside of the cleaning box 607 by the conveying roller 606 and sent into the stacking conveyor belt 901, and moves right along the stacking conveyor belt 901. When the second sensor 909 on the stacking conveyor belt 901 senses the tray body 401, the stacking conveyor belt 901 is stopped from running by the automatic control console 3, and the tray body 401 is stopped between the support frames 902. At the same time, the automatic control console 3 controls the driving servo motor 601 to temporarily stop running, leaving time for subsequent operations. At this time, the inclined slider 908 is just inside the sliding slot 402. Then the automatic control console 3 controls the electric push rod 904 to push the connecting plate 905 to push the tray body 401 upwards. Then the automatic control console 3 continues to start the driving servo motor 601 and the stacking conveyor belt 901 to transport the tray body 401. When the next tray body 401 is stopped between the support frames 902, the automatic control console 3 controls the electric push rod 904 to retract to stack the last tray body 401 downwards, and the steam sterilization structure 10 is stacked with each other through the jacking rod 403 and the fixed groove 404. Under the drive of the electric push rod 904, the inclined slider 908 slides along the sliding guide column 906 outwardly against the elastic force of the top spring 907, and stops until it is inside the sliding slot 402 on the lower tray body 401. Then the above operation is repeated once. When the automatic control console 3 senses the stacking count 3 through the second sensor 909, the second sensor 909 no longer pauses the stacking conveyor belt 901 through the automatic control console 3, but sends the stacked tray body 401 into the steam sterilization structure 10 along the stacking conveyor belt 901 for steam sterilization treatment. After the stacked tray body 401 is sent out, the stacking mechanism 9 continues to repeat the above operation.

[0047] The box mechanism 11 comprises a steam sterilization box 1101, a sliding door 1103, and the steam sterilization box 1101 is internally provided with sliding grooves 1102 on the left and right sides and the lower side, the outer surface of the sliding door 1103 is in sliding connection with the inner surface of the sliding groove 1102, the left and right ends of the rear side of the sliding door 1103 are fixedly connected with sliding blocks 1104, the left and right sides of the steam sterilization box 1101 are fixedly connected with side sliding frames 1105, the outer surface of the sliding block 1104 is in sliding connection with the inner surface of the side sliding frame 1105, the middle part of the sliding block 1104 is threadedly connected with a lifting screw rod 1107, the upper and lower ends of the lifting screw rod 1107 are rotatably connected with the inner side of the side sliding frame 1105, the upper end of the lifting screw rod 1107 is fixedly connected with the output end of a lifting servo motor 1108, the left and right sides of the steam sterilization box 1101 are fixedly connected with second sliding rails 1106, the inside of the steam sterilization box 1101 is provided with a steel mesh conveyor belt 1109, the lower side of the box mechanism 11 is fixedly connected with a steam mechanism 12, the front side of the box mechanism 11 is provided with a pushing mechanism 13, and the lifting servo motor 1108 and the steel mesh conveyor belt 1109 are electrically connected with the automatic control console 3.

[0048] Specifically, when the stacked tray body 401 enters the pushing mechanism 13 along the stacking conveyor belt 901, the idle box mechanism 11 will drive the lifting screw rod 1107 on the side sliding frame 1105 to rotate through the lifting servo motor 1108, drive the sliding block 1104 and the sliding door 1103 to move downward along the sliding groove 1102, open the sliding door 1103, then the pushing mechanism 13 pushes the stacked tray body 401 along the 110 driving mechanism 6 into the steel mesh conveyor belt 1109, at the same time, the automatic control console 3 also starts the steel mesh conveyor belt 1109 to move the stacked tray body 401 to the inside of the steam sterilization box 1101, then the automatic control console 3 controls the lifting servo motor 1108 to close the sliding door 1103, and injects high-temperature steam into the steam sterilization box 1101 through the steam mechanism 12, and the culture containers 407 on the tray body 401 are subjected to steam sterilization, when the set time is reached, the automatic control console 3 closes the steam mechanism 12, and controls the lifting servo motor 1108 to open the sliding door 1103, then the automatic control console 3 controls the steel mesh conveyor belt 1109 to push the sterilized tray body 401 out of the inside of the steam sterilization box 1101, and repeats the above steps.

[0049] The steam mechanism 12 comprises high-temperature steam pipes 1201, condensate water collection buckets 1204 and exhaust pipes 1202. The lower ends of the high-temperature steam pipes 1201 are fixedly connected to the upper side of the steam sterilization box 1101. The front ends of the exhaust pipes 1202 are fixedly connected to the rear side of the steam sterilization box 1101. The middle parts of the exhaust pipes 1202 are fixedly connected with exhaust pipe valves 1203. The upper surfaces of the condensate water collection buckets 1204 are fixedly connected with the lower surfaces of the steam sterilization box 1101. The lower surfaces of the condensate water collection buckets 1204 are fixedly connected with condensate water discharge pipes 1205. The middle parts of the condensate water discharge pipes 1205 are fixedly connected with condensate water discharge valves 1206. The exhaust pipe valves 1203 and the condensate water discharge valves 1206 are electrically connected with the automatic control console 3.

[0050] Specifically, after the automatic control console 3 controls the pushing mechanism 13 and the steel mesh conveyor 1109 to move the stacked tray bodies 401 into the steam sterilization box 1101 and closes the sliding door 1103, the automatic control console 3 controls the exhaust pipe valves 1203 and the condensate water discharge valves 1206 to be closed, and injects high-temperature steam into the steam sterilization box 1101 through the high-temperature steam pipes 1201 to sterilize the culture containers 407 on the tray bodies 401. After a set time, the automatic control console 3 controls the high-temperature steam pipes 1201 to stop inputting steam, opens the exhaust pipe valves 1203 to exhaust the residual steam in the steam sterilization box 1101 through the exhaust pipes 1202, opens the condensate water discharge valves 1206 to discharge the condensate water collected in the condensate water collection buckets 1204 along the condensate water discharge pipes 1205, and prepares to repeat the above steps.

[0051] The pushing mechanism 13 comprises auxiliary feeding conveyors 1301 and fixed frames 1302. The auxiliary feeding conveyors 1301 are arranged on the front side of the steam sterilization box 1101. The front side of each auxiliary feeding conveyor 1301 is provided with a fixed frame 1302. The middle part of each fixed frame 1302 is fixedly connected with a plurality of feeding pushing rods 1303. The rear end of each feeding pushing rod 1303 is fixedly connected with a pushing plate 1304. The right side of each fixed frame 1302 is provided with a third sensor 1305. The adjacent sides of the auxiliary feeding conveyors 1301 are provided with connecting conveyors 1306. The front side of each connecting conveyor 1306 is provided with a fourth sensor 1307. The right side of the pushing mechanism 13 is provided with a microwave sterilization mechanism 14. The feeding pushing rods 1303, the third sensors 1305, the connecting conveyors 1306 and the fourth sensors 1307 are electrically connected with the automatic control console 3.

[0052] Specifically, when the stacked tray body 401 is sent into the sub-feeding conveyor 1301 along the stacking conveyor 901, the automatic control console 3 can sense whether there is a tray body 401 on the sub-feeding conveyor 1301 through the connection of the third sensor 1305 and the automatic control console 3, and decide whether to send the tray body 401 into the box mechanism 11 in combination with the use of the box mechanism 11 inside the automatic control console 3. When there is an idle box mechanism 11, the automatic control console 3 will control the sub-feeding conveyor 1301 to cooperate with the connecting conveyor 1306 to send the stacked tray body 401 to the sub-feeding conveyor 1301 corresponding to the idle box mechanism 11, and control the feeding push rod 1303 on the fixed frame 1302 to push the push plate 1304 to send the stacked tray body 401 into the idle box mechanism 11. When the box mechanism 11 completes the set time of the steam sterilization process and sends the sterilized tray body 401 back to the sub-feeding conveyor 1301, the automatic control console 3 will control the sub-feeding conveyor 1301 to cooperate with the connecting conveyor 1306 to send the sterilized tray body 401 into the microwave sterilization mechanism 14 for microwave sterilization treatment. When there is no idle box mechanism 11, the automatic control console 3 will control the sub-feeding conveyor 1301 to send the stacked tray body 401 along the sub-feeding conveyor 1301 into the connecting conveyor 1306 and temporarily place it on the connecting conveyor 1306 until the idle box mechanism 11 on the right side appears, and then the connecting conveyor 1306 is started by the automatic control console 3 to send the tray body 401 out for sterilization. At the same time, the fourth sensor 1307 can detect whether there is a tray body 401 on the connecting conveyor 1306. When the connecting conveyor 1306 is full, the driving mechanism 6 and the stacking mechanism 9 will be paused by the automatic control console 3 until the box mechanism 11 starts to be idle. Through the cooperation of the automatic control console 3, the box mechanism 11, the steam mechanism 12 and the pushing mechanism 13, the steam sterilization structure 10 can be efficiently and automatically operated, and the overall work efficiency of the sterilization device is improved.

[0053] The microwave sterilization mechanism 14 comprises a microwave feeding conveyor 1401 and a fifth sensor 1402. The microwave feeding conveyor 1401 is arranged on the right side of the pushing mechanism 13, and the fifth sensor 1402 is arranged on the front and back sides of the microwave feeding conveyor 1401. A microwave sterilization box 1403 is arranged on the right side of the microwave feeding conveyor 1401. Side gas collectors 1404 are fixedly connected to the front and back sides of the microwave sterilization box 1403. Side air outlet pipes 1405 are fixedly connected to the sides away from each other of the side gas collectors 1404. A discharging conveyor 1406 is arranged on the right side of the microwave sterilization box 1403. The microwave feeding conveyor 1401, the fifth sensor 1402, the microwave sterilization box 1403 and the discharging conveyor 1406 are electrically connected to the automatic control console 3.

[0054] Specifically, when the stacked tray body 401 is sent into the microwave feeding conveyor belt 1401 along the sub-feeding conveyor belt 1301 after the steam sterilization treatment of the steam sterilization structure 10, the microwave sterilization box 1403 is started by the automatic control console 3 to perform secondary sterilization treatment on the culture containers 407 on the tray body 401 entering the microwave sterilization box 1403 along the microwave feeding conveyor belt 1401 after the fifth sensor 1402 senses the tray body 401. At the same time, due to the characteristics of the microwave, the residual moisture on the tray body 401 and the culture containers 407 can be dried at the same time of sterilization. The evaporated water vapor is extracted along the side gas collector 1404 by the side air outlet pipe 1405 to ensure the sterilization effect inside the microwave sterilization box 1403. After the culture containers 407 on the tray body 401 complete the secondary sterilization inside the microwave sterilization box 1403, the tray body 401 is sent out of the equipment along the microwave feeding conveyor belt 1401 to complete the whole sterilization process.

[0055] Although the embodiments of the present application have been shown and described, it is to be understood that various changes, modifications, substitutions and alterations can be made to the embodiments without departing from the principles and spirit of the present application, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A sterilization device for a vaccinia virus production workshop, comprising a main feed conveyor belt (1), characterized in that, The main feeding conveyor belt (1) is equipped with a first sensor (2) on both the front and rear sides. An automatic control console (3) is provided on the rear side of the main feeding conveyor belt (1). A tray mechanism (4) is provided on the upper surface of the main feeding conveyor belt (1). The tray mechanism (4) includes a tray body (401) and a culture container (407). The tray mechanism (4) can protect and fix the culture container (407). The first sensor (2) is electrically connected to the automatic control console (3). A cleaning mechanism (5) is provided on the right side of the main feed conveyor belt (1). The cleaning mechanism (5) includes a drive mechanism (6), a rinsing mechanism (7), and an air jet mechanism (8). The drive mechanism (6) includes a rotating shaft (605) and a conveyor roller (606). The conveyor roller (606) can smoothly transport the tray mechanism (4) into the cleaning mechanism (5), so that the rinsing mechanism (7) and the air jet mechanism (8) in the cleaning mechanism (5) can clean the culture container (407) on the tray mechanism (4). The rinsing mechanism (7) includes a high-pressure nozzle (703) and a water collection hopper (704). The high-pressure nozzle (703) arranged opposite to each other can rinse and clean the upper and lower surfaces of the culture container (407). The air jet mechanism (8) includes an air inlet pipe (801) and an air jet port (802). The air jet port (802) arranged opposite to each other can spray and clean the culture container (407). A stacking mechanism (9) is provided on the right side of the cleaning mechanism (5), and a steam sterilization structure (10) is provided on the right side of the stacking mechanism (9). The stacking mechanism (9) can stack the tray body (401) in multiple layers, which makes it convenient to send the culture containers (407) into the subsequent steam sterilization structure (10) for sterilization. The steam sterilization structure (10) includes a box mechanism (11), a steam mechanism (12), and a pushing mechanism (13). A microwave sterilization mechanism (14) is provided on the right side of the pushing mechanism (13).

2. The sterilization equipment for a vaccinia virus production workshop according to claim 1, characterized in that, The tray mechanism (4) further includes a slide groove (402) and a top rod (403). The outer edge of the tray body (401) is provided with a slide groove (402). The upper surface of the tray body (401) is fixedly connected to the lower end of multiple sets of top rods (403). The lower surface of the tray body (401) is provided with multiple sets of fixing grooves (404). The middle of the inner surface of the tray body (401) is fixedly connected with a connecting frame (405). The upper surface of the connecting frame (405) is fixedly connected with multiple sets of protrusions (406). The protrusions (406) are slidably connected to the inner surface of the culture container (407).

3. The sterilization equipment for a vaccinia virus production workshop according to claim 1, characterized in that, The drive mechanism (6) further includes a drive servo motor (601), a steering reducer (602), and a cleaning housing (607). The front and rear sides of the cleaning housing (607) are fixedly connected to the adjacent sides of the drive servo motor (601). The output ends of the drive servo motor (601) are fixedly connected to the input ends of the steering reducer (602). The adjacent sides of the steering reducer (602) are fixedly connected to the front and rear sides of the drive servo motor (601). The output ends of the steering reducer (602) are fixedly connected to the outer ends of the left and right rotating shafts (605). (605) All shafts pass through the front and rear sides of the drive servo motor (601) and are rotatably connected to the cleaning box (607). The middle of each shaft (605) is fixedly connected to a transmission gear (603). The transmission gears (603) are meshed with each other through a transmission chain (604). The adjacent ends of each shaft (605) are fixedly connected to the middle of the conveyor roller (606). The outer edge of each conveyor roller (606) is slidably connected to the inner surface of the slide groove (402). The drive servo motor (601) is electrically connected to the automatic control console (3).

4. The sterilization equipment for a vaccinia virus production workshop according to claim 1, characterized in that, The rinsing mechanism (7) also includes an inlet pipe (701) and a branch pipe (702). The middle part of the inlet pipe (701) is fixedly connected to the front and rear ends of the branch pipe (702). The front and rear sides of the branch pipe (702) pass through the front and rear sides of the cleaning box (607) and are fixedly connected to the cleaning box (607). The adjacent ends of the branch pipe (702) are fixedly connected to the input end of the high-pressure nozzle (703). The lower side of the cleaning box (607) is fixedly connected to the upper surface of the water collection hopper (704). A drain pipe (705) is fixedly connected to the middle part of the water collection hopper (704).

5. The sterilization equipment for a vaccinia virus production workshop according to claim 1, characterized in that, The jet mechanism (8) also includes a first slide rail (803). The middle part of the air inlet pipe (801) passes through the front and rear sides of the cleaning box (607) and is fixedly connected to the cleaning box (607). The adjacent ends of the air inlet pipe (801) are fixedly connected to the front and rear sides of the jet nozzle (802). The output ends of the jet nozzle (802) are arranged opposite to each other.

6. The sterilization equipment for a vaccinia virus production workshop according to claim 1, characterized in that, The stacking mechanism (9) includes a stacking conveyor belt (901) and a second sensor (909). The stacking conveyor belt (901) is located on the right side of the cleaning box (607). Support frames (902) are fixedly connected to both the front and rear sides of the middle of the stacking conveyor belt (901). Multiple sets of fixing plates (903) are fixedly connected to the outer sides of the support frames (902). Electric push rods (904) are fixedly connected to the middle of the fixing plates (903). Connecting plates (905) are fixedly connected to the upper ends of the electric push rods (904). A sliding connection is made to the middle of the connecting plates (905). Multiple sets of sliding guide posts (906) are provided, and each adjacent end of the sliding guide post (906) is fixedly connected to an inclined slider (908). Each sliding guide post (906) between the outer side of the inclined slider (908) and the adjacent side of the connecting plate (905) is provided with a top spring (907). Each support frame (902) is provided with a second sensor (909) on its right side. Each stacking conveyor belt (901) is provided with a steam sterilization structure (10) on its right side. The stacking conveyor belt (901), the electric push rod (904), and the second sensor (909) are all electrically connected to the automatic control console (3).

7. The sterilization equipment for a vaccinia virus production workshop according to claim 1, characterized in that, The chamber mechanism (11) includes a steam sterilization chamber (1101) and a sliding door (1103). Sliding grooves (1102) are provided on the left, right, and lower sides of the interior of the steam sterilization chamber (1101). The outer surface of the sliding door (1103) is slidably connected to the inner surface of the sliding groove (1102). Slider blocks (1104) are fixedly connected to the rear sides of both the left and right ends of the sliding door (1103). Side slides (1105) are fixedly connected to both the left and right sides of the steam sterilization chamber (1101). The outer surface of the slider (1104) is slidably connected to the inner surface of the side slide (1105). A lifting screw (1107) is threadedly connected to the middle of each slider (1104). The upper and lower ends of the lifting screw (1107) are... All are rotatably connected to the inner side of the side slide frame (1105). The upper end of the sliding groove (1102) is fixedly connected to the lifting servo motor (1108). The output end of the lifting servo motor (1108) is fixedly connected to the upper end of the lifting screw (1107). The inner surfaces of the left and right sides of the steam sterilization chamber (1101) are fixedly connected to the second slide rail (1106). The lower side of the interior of the steam sterilization chamber (1101) is provided with a steel mesh conveyor belt (1109). The lower side of the chamber mechanism (11) is fixedly connected to the steam mechanism (12). The front side of the chamber mechanism (11) is provided with a pushing mechanism (13). The lifting servo motor (1108) and the steel mesh conveyor belt (1109) are electrically connected to the automatic control console (3).

8. The sterilization equipment for a vaccinia virus production workshop according to claim 7, characterized in that, The steam mechanism (12) includes a high-temperature steam pipe (1201), a condensate collection hopper (1204), and an exhaust pipe (1202). The lower ends of the high-temperature steam pipes (1201) are fixedly connected to the upper side of the steam sterilization chamber (1101), and the front ends of the exhaust pipes (1202) are fixedly connected to the rear side of the steam sterilization chamber (1101). An exhaust pipe valve (1203) is fixedly connected to the middle of each exhaust pipe (1202). The upper surface of the condensate collection hopper (1204) is fixedly connected to the lower surface of the steam sterilization chamber (1101). The lower surface of the condensate collection hopper (1204) is fixedly connected to a condensate drain pipe (1205). The middle part of the condensate drain pipe (1205) is fixedly connected to a condensate drain valve (1206). The exhaust pipe valve (1203) and the condensate drain valve (1206) are electrically connected to the automatic control console (3).

9. The sterilization equipment for a vaccinia virus production workshop according to claim 7, characterized in that, The feeding mechanism (13) includes a secondary feeding conveyor belt (1301) and a fixed frame (1302). The secondary feeding conveyor belts (1301) are all located on the front side of the steam sterilization chamber (1101). A fixed frame (1302) is provided on the front side of each secondary feeding conveyor belt (1301). Multiple sets of feeding push rods (1303) are fixedly connected to the middle of each fixed frame (1302). A push plate (1304) is fixedly connected to the rear end of each feeding push rod (1303). The fixed frame (1302)... A third sensor (1305) is provided on the right side of each of the auxiliary feeding conveyor belts (1301) and a connecting conveyor belt (1306) is provided on the adjacent side of each of the auxiliary feeding conveyor belts (1301). A fourth sensor (1307) is provided on the front side of each of the connecting conveyor belts (1306). A microwave sterilization mechanism (14) is provided on the right side of the pushing mechanism (13). The feeding push rod (1303), the third sensor (1305), the connecting conveyor belt (1306), and the fourth sensor (1307) are all electrically connected to the automatic control console (3).

10. The sterilization equipment for a vaccinia virus production workshop according to claim 9, characterized in that, The microwave sterilization mechanism (14) includes a microwave feeding conveyor belt (1401) and a fifth sensor (1402). The microwave feeding conveyor belt (1401) is located on the right side of the pushing mechanism (13). The fifth sensor (1402) is located on the front and rear sides of the microwave feeding conveyor belt (1401). A microwave sterilization chamber (1403) is located on the right side of the microwave feeding conveyor belt (1401). Side air collection hoppers (1404) are fixedly connected to both the front and rear sides of the microwave sterilization chamber (1403). Side air outlet pipes (1405) are fixedly connected to the opposite sides of the side air collection hoppers (1404). A discharge conveyor belt (1406) is located on the right side of the microwave sterilization chamber (1403). The microwave feeding conveyor belt (1401), the fifth sensor (1402), the microwave sterilization chamber (1403), and the discharge conveyor belt (1406) are all electrically connected to the automatic control console (3).

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