Process for the recovery and use of a stream containing methyl 4-acetyloxybutanoate

By catalyzing γ-butyrolactone and methyl 4-acetoxybutyrate under azeotropic distillation to generate sodium α-acetyl-γ-butyrolactone, and separating impurities through extraction and vacuum distillation, the problems of low yield and impurities in the production of α-acetyl-γ-butyrolactone were solved, achieving a highly efficient and environmentally friendly production process.

CN117285489BActive Publication Date: 2026-05-08NINGXIA TIANXIN PHARM CO LTD
4 Cites 0 Cited by

Patent Information

Application Number
CN202311011899.2
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-08-11
Publication Date
2026-05-08
Estimated Expiration
2043-08-11

AI Technical Summary

Technical Problem

In the existing technology, the production of α-acetyl-γ-butyrolactone contains methyl 4-acetoxybutyrate impurities, resulting in low yield and low utilization of γ-butyrolactone, posing safety hazards and high costs.

Method used

Sodium methoxide was used as a catalyst to react γ-butyrolactone and methyl 4-acetoxybutyrate with methyl acetate under azeotropic distillation conditions to generate sodium α-acetyl-γ-butyrolactone. Impurities were separated by extraction and vacuum distillation to improve yield and purity.

Benefits of technology

It improved the yield and purity of α-acetyl-γ-butyrolactone, reduced waste liquid volume, lowered production costs and energy consumption, improved the utilization rate of γ-butyrolactone, and reduced equipment investment and production cycle.

✦ Generated by Eureka AI based on patent content.
Patent Text Reader

Abstract

The present application relates to the chemical technology field, disclose a kind of recycling method and application of 4-acetyloxy butyric acid methyl ester material.The method comprises: (1) in the presence of sodium methoxide, the raw material containing γ-butyrolactone and 4-acetyloxy butyric acid methyl ester and methyl acetate are made to carry out acylation reaction, while azeotropic distillation is carried out, obtain the dry material containing α-acetyl-γ-butyrolactone sodium salt;(2) the dry material is extracted after being handled and separated, obtain α-acetyl-γ-butyrolactone crude product;(3) the crude product is subjected to vacuum rectification, separate out γ-butyrolactone and 4-acetyloxy butyric acid methyl ester mixture, obtain α-acetyl-γ-butyrolactone fine product.The method fully recycles 4-acetyloxy butyric acid methyl ester produced by α-acetyl-γ-butyrolactone, reduces waste liquid disposal amount;Avoid 4-acetyloxy butyric acid methyl ester and γ-butyrolactone separation, reduce energy loss;Prepared α-acetyl-γ-butyrolactone has higher yield and purity.
Need to check novelty before this filing date? Find Prior Art