A Chinese medicinal composition for preventing and treating piglet diarrhea and a preparation method thereof
The traditional Chinese medicine compositions prepared by using traditional Chinese medicine compositions such as Coptis chinensis have solved the problems of drug residues and resistance caused by antibiotics, and effectively prevent and treat diarrhea in piglets, enhance immunity and reduce mortality and morbidity. It has the advantages of safety, environmental protection and low cost.
Patent Information
- Application Number
- CN202410765359.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-14
- Publication Date
- 2025-01-07
- Estimated Expiration
- 2044-06-14
AI Technical Summary
The prior art relies on antibiotics in preventing and treating diarrhea in piglets, which leads to drug residues and drug resistance problems, and has an impact on intestinal microorganisms, making it difficult to effectively reduce the mortality and morbidity of piglets.
A Chinese medicine composition is used, including coptis chinensis, palm seeds, jealous flowers, water chestnuts, yam, lysodium sinewal, kapok peel, jujube and charred hawthorn, and is prepared into powder and oral liquid by crushing, mixing and sterilizing, Granules or capsules are used to prevent and treat diarrhea in piglets.
This traditional Chinese medicine composition has the effects of astringing intestines and stopping diarrhea, clearing heat and dampness, strengthening the spleen and kidneys, enhancing the immunity of piglets, reducing the incidence and mortality, and has no drug residues and drug resistance, and is safe to use and low cost.
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Figure CN118320013B_ABST
Abstract
Description
Technical Field
[0001] The invention belongs to the technical field of veterinary drugs, and particularly relates to a traditional Chinese medicine composition for preventing and treating piglet diarrhea and a preparation method thereof. Background Art
[0002] It is reported that piglet diarrhea is a major problem in the pig farming industry, and the subsequent piglet mortality rate is as high as over 25%. In particular, the incidence of newborn piglet diarrhea is difficult to reduce, which has a serious impact on the pig farming industry. Piglet diarrhea can occur all year round, especially in spring and winter. There are many causes of piglet diarrhea, such as poor insulation in the pig house when it is cold, damp and unventilated pig houses, inadequate disinfection, indigestion of food, vertical transmission from sows, bacterial and viral infections, and piglet stress and feed mold. The hazards of piglet diarrhea include increased piglet mortality, reduced piglet immunity, prolonged market time, and increased feeding costs.
[0003] According to the basic theory of Chinese veterinary medicine, diarrhea caused by cold in piglets is watery, thin, cold, painful and borborygmus in the abdomen. Piglets like warmth and hate cold. If diarrhea is not treated and the course of the disease is prolonged, the stool is loose and yellowish brown, and the stool is foul-smelling, which is mostly a sign of damp heat. Loose stool, undigested food, and foul smell are mostly signs of food injury. After eating, the stomach is stuffy and uncomfortable, the complexion is earthy, and the depression is tired and weak. Most of them are diseases in the spleen. Diarrhea at five o'clock, undigested food, cold pain in the lower abdomen, and cold limbs are mostly diseases in the kidney. The body temperature rises, the spirit is depressed, vomiting is accompanied by dehydration, the feces are fishy and watery and mostly yellow, undigested food, diarrhea is like a flood and is in the shape of a jet, the body is thin, and the person is afraid of the cold and curled up or huddled together, which is mostly bacterial and viral diarrhea.
[0004] At present, antibiotics are mostly used in clinical prevention and treatment of piglet diarrhea, but the drug residues and drug resistance of antibiotics, coupled with long-term and large-scale use, will definitely affect the normal intestinal microbial flora of the body, and may cause adverse reactions such as intestinal dysfunction. With the advent of the era of reducing antibiotics, reducing antibiotics and replacing them is the best strategy. Therefore, we must give full play to the unique advantages of traditional Chinese medicine and its role in clinical prevention and treatment of piglet diarrhea. Summary of the invention
[0005] The present invention aims to use a traditional Chinese medicine formula to replace antibiotics in the prevention and treatment of piglet diarrhea, and to provide a traditional Chinese medicine composition that can effectively prevent and treat piglet diarrhea, has good effects, is simple in preparation method, is low in cost, is natural and has no drug residues.
[0006] To achieve the purpose of the present invention, the technical solutions adopted are as follows:
[0007] The traditional Chinese medicine composition provided by the invention consists of the following raw materials in parts by weight: 6-10 parts of rheumatism thorns, 15-20 parts of palm seeds, 6-10 parts of knotweed flowers, 3-7 parts of euryale seeds, 3-7 parts of yam, 12-18 parts of liaowulong, 6-10 parts of kapok peels, 2-5 parts of jujubes and 3-7 parts of charred hawthorns.
[0008] Preferably, the Chinese medicine composition is composed of the following raw materials in parts by weight: 7-9 parts of Rheum officinale thorns, 16-18 parts of palm seeds, 7-9 parts of knotweed flowers, 4-6 parts of Euryale ferox, 4-6 parts of yam, 14-16 parts of Liaowasong, 7-9 parts of kapok peels, 3-5 parts of jujubes, and 4-6 parts of charred hawthorn.
[0009] More preferably, the Chinese medicine composition is composed of the following raw materials in parts by weight: 8 parts of Rheum officinale thorns, 18 parts of palm seeds, 8 parts of Flos Caryophyllus, 5 parts of Euryale ferox, 5 parts of Dioscorea opposita, 15 parts of Castanopsis lycopodii, 8 parts of Kapok bark, 4 parts of jujubes, and 5 parts of charred Crataegus pinnatifida.
[0010] More preferably, the Chinese medicine composition is characterized in that: the Chinese medicine composition is in the form of powder, oral liquid, granules, capsule or tablet.
[0011] More preferably, the dosage form of the Chinese medicine composition is a powder.
[0012] The preparation method for preparing the above-mentioned Chinese medicine composition is as follows:
[0013] The first step is to weigh the raw materials according to the weight ratio: 6-10 parts of Rheum officinale thorn, 15-20 parts of palm seeds, 6-10 parts of knotweed flowers, 3-7 parts of Euryale ferox, 3-7 parts of yam, 12-18 parts of Liaowasong, 6-10 parts of kapok peel, 2-5 parts of jujube, and 3-7 parts of charred hawthorn, and the above raw materials are cleaned, impurity-removed, washed, and dried;
[0014] The second step is to fully crush the above raw materials, pass them through a 80-120 mesh sieve, mix them evenly, sterilize and package them to obtain the Chinese medicine composition of the present invention.
[0015] The mesh size of the sieve is 80-120 meshes, preferably 80-100 meshes.
[0016] The effects and functions of the components of the Chinese medicine composition of the present invention are:
[0017] Rhubarb thorn: Nature and flavor, bitter, cold; Meridians: liver, stomach and small intestine; Main effects and functions: clearing away heat and dampness, purging fire and detoxifying. Indications: damp-heat diarrhea, dysentery, jaundice, hot stranguria, sore throat, mouth sores and gingival swelling, red and swollen eyes due to fire, mumps, breast abscess, furuncle, and burns; This product is the root and stem of Berberis chinensis, a plant of the Berberidaceae family.
[0018] Palm seeds: nature and flavor, and meridians: bitter and flat, entering the spleen and large intestine meridians; functions: astringent to the intestines, consolidating semen, and stopping bleeding, mainly used to treat diarrhea, metrorrhagia, leucorrhea, and spermatorrhea; this product is the mature fruit of the palm plant of the palm family.
[0019] Herba Alternariae: bitter and cool in nature and flavor, enters the heart and small intestine meridians; functions: clearing away heat, promoting diuresis, and detoxifying. It is mainly used to treat dysentery, coughing and vomiting blood, intestinal wind and blood, gonorrhea, carbuncle, swelling and eczema; this product is the whole herb or the whole herb with roots of the Amaranthaceae plant Alternaria.
[0020] Gorgon fruit: nature and flavor, flat, sweet, astringent; meridians entered, spleen and kidney; functions, strengthening the kidney and astringing the essence, tonifying the spleen and stopping diarrhea, mainly treating diarrhea, spermatorrhea, stranguria, leucorrhea, and incontinence; this product is the dried mature seed kernel of the Gorgon fruit of the Nymphaeaceae family.
[0021] Chinese Yam: sweet, neutral in nature; enters the lung, spleen, and kidney meridians. Functions: tonify the spleen, nourish the lungs, strengthen the kidneys, and benefit the essence. It is used to treat diarrhea due to spleen deficiency, edema due to loss of appetite, cough and asthma due to lung deficiency, thirst, spermatorrhea, leucorrhea, frequent urination due to kidney deficiency, and external treatment of carbuncle and scrofula; this product is the rhizome of the Dioscorea plant of the Dioscorea family.
[0022] Liaowasong: Nature and flavor, sour, flat; Meridians: liver and large intestine; Functions: cooling blood, stopping dysentery, detoxifying and healing sores, it is used to treat diarrhea, bloody stool, metrorrhagia, sores, and burns; This product is the above-ground part of the Crassulaceae plant Liaowasong.
[0023] Kapok bark: nature and flavor, pungent, neutral; meridians entered, stomach meridian, large intestine meridian; effects, clearing away heat and detoxifying, dispersing blood stasis and stopping bleeding, treating wind-induced diarrhea, dysentery, rheumatism and pain, chronic gastritis, gastric ulcer, metrorrhagia, sores, boils, swelling and pain; this product is the bark of the kapok plant of the Bombacaceae family.
[0024] Jujube: nature and flavor, sweet and warm; enters the spleen and stomach meridians; has the effects of tonifying the spleen and stomach, replenishing qi and producing body fluid, regulating the body's defense system, and detoxifying drugs. It is used to treat stomach deficiency, poor appetite, weak spleen and loose stools, insufficient qi and blood, disharmony between the body's defense system, palpitations, and restlessness in women; this product is the dried mature fruit of the jujube plant of the genus Ziziphus of the Rhamnaceae family.
[0025] Scorched Hawthorn: Nature and flavor: sour, sweet, slightly warm; Meridians: enter the spleen, stomach, and liver meridians; Functions: help digestion and invigorate the stomach, promote blood circulation and remove blood stasis, used for diarrhea, abdominal pain due to diarrhea, meat stagnation, epigastric distension, amenorrhea due to blood stasis, postpartum blood stasis, stabbing pain in the heart and abdomen, hernia pain, and hyperlipidemia; this product is a processed product of Hawthorn.
[0026] By adopting the above technical solution, the present invention has the following beneficial effects:
[0027] 1. The present invention belongs to a pure Chinese medicine preparation, which is natural, additive-free, drug-free and drug-free, and has no withdrawal period. It is a green, environmentally friendly, safe and effective Chinese medicine preparation.
[0028] 2. The ingredients in the prescription of the present invention are synergistic and simple to prepare. The medicinal materials have a large area after being crushed and are easy to absorb and exert their medicinal effects.
[0029] The beneficial effects of the present invention are as follows: the Chinese medicine composition provided by the present invention has the effects of astringing the intestines and stopping diarrhea, clearing away heat and removing dampness, strengthening the spleen and kidneys, and promoting digestion and strengthening the stomach. While preventing and treating piglet diarrhea, it can enhance the immunity of piglets and reduce the morbidity and mortality of piglets. The present invention has a good therapeutic effect on piglet diarrhea caused by indigestion, bacteria, viruses and poor pig house breeding environment. The present invention belongs to a pure natural Chinese medicine preparation, which has the advantages of treating both the symptoms and the root causes, safe use, high cure rate, no drug resistance, and low use cost in preventing and treating piglet diarrhea. BRIEF DESCRIPTION OF THE DRAWINGS
[0030] Figure 1 This is the case of the blank control group in Experimental Example 2 where no modeling mice were established.
[0031] Figure 2 This is the diarrhea condition of mice in the model control group in Experimental Example 2.
[0032] Figure 3 This is the situation of piglets in Test Group 1 before drug administration in the clinical trial of Test Example 3.
[0033] Figure 4 This is the situation of piglets in test group 1 on the 5th day of administration in the clinical trial of test example 3. DETAILED DESCRIPTION
[0034] Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in the field without making any creative work shall fall within the scope of protection of the present invention.
[0035] The present invention is further explained below in conjunction with specific implementation modes.
[0036] Example 1
[0037] The present embodiment provides a traditional Chinese medicine composition for preventing and treating diarrhea in piglets, which is prepared from the following raw materials in parts by weight: 8 parts of Rheum officinale thorns, 18 parts of palm seeds, 8 parts of knotweed flowers, 5 parts of Euryale ferox, 5 parts of yam, 15 parts of Liaowasong, 8 parts of kapok peels, 4 parts of jujubes, and 5 parts of charred hawthorn.
[0038] The preparation method of the Chinese medicine composition of this embodiment is as follows:
[0039] The first step is to weigh the raw materials according to the weight ratio: 8 parts of rhubarb thorn, 18 parts of palm seeds, 8 parts of knotweed, 5 parts of Euryale ferox, 5 parts of yam, 15 parts of Liaowasong, 8 parts of kapok peel, 4 parts of jujube, and 5 parts of charred hawthorn, and the above raw materials are cleaned, removed from impurities, washed, and dried;
[0040] The second step is to fully crush the above raw materials, pass them through a 100-mesh sieve, mix them evenly, sterilize and package them to obtain the Chinese medicine composition of the present invention.
[0041] Example 2
[0042] The present embodiment provides a traditional Chinese medicine composition for preventing and treating diarrhea in piglets, which is prepared from the following raw materials in parts by weight: 8 parts of Rheum officinale thorns, 15 parts of palm seeds, 8 parts of knotweed flowers, 5 parts of Euryale ferox, 5 parts of yam, 12 parts of Liaowasong, 8 parts of kapok peels, 2 parts of jujubes, and 3 parts of charred hawthorn.
[0043] The preparation method of this example is referenced to Example 1.
[0044] Example 3
[0045] The present embodiment provides a traditional Chinese medicine composition for preventing and treating diarrhea in piglets, which is prepared from the following raw materials in parts by weight: 8 parts of Rheum officinale thorns, 20 parts of palm seeds, 8 parts of Flos Eupatorii, 7 parts of Euryale ferox, 5 parts of Dioscorea opposita, 16 parts of Castanopsis lycopodii, 8 parts of Kapok peel, 4 parts of jujube, and 6 parts of charred Crataegus pinnatifida.
[0046] The preparation method of this example is referenced to Example 1.
[0047] Example 4
[0048] The present embodiment provides a traditional Chinese medicine composition for preventing and treating diarrhea in piglets, which is prepared from the following raw materials in parts by weight: 8 parts of Rheum officinale thorns, 15 parts of palm seeds, 10 parts of knotweed flowers, 6 parts of Euryale ferox, 5 parts of yam, 12 parts of Liaowasong, 10 parts of kapok peels, 4 parts of jujubes, and 5 parts of charred hawthorn.
[0049] The preparation method of this example is referenced to Example 1.
[0050] Example 5
[0051] The present embodiment provides a traditional Chinese medicine composition for preventing and treating diarrhea in piglets, which is prepared from the following raw materials in parts by weight: 8 parts of Rheum officinale thorns, 18 parts of palm seeds, 10 parts of knotweed flowers, 5 parts of Euryale ferox, 5 parts of yam, 12 parts of Liaowasong, 8 parts of kapok peels, 4 parts of jujubes, and 4 parts of charred hawthorns.
[0052] The preparation method of the Chinese medicine composition of this embodiment is as follows:
[0053] The first step is to weigh the raw materials according to the weight ratio: 8 parts of Rheum officinale thorn, 18 parts of palm seeds, 10 parts of knotweed flowers, 5 parts of Euryale ferox, 5 parts of yam, 12 parts of Liaowasong, 8 parts of kapok peel, 4 parts of jujube, and 4 parts of charred hawthorn, and the above raw materials are cleaned, removed from impurities, washed, crushed, and sieved; and sieved through a No. 2 sieve;
[0054] Step 2: Take 10-12 times the total weight of all the above raw materials and soak the sieved raw materials in water for 0.5-1h; then boil and simmer for 1.5h;
[0055] The third step is to filter the Chinese medicine in the second step, add 8-10 times the total weight of the medicinal materials into the residue and boil for 1 hour;
[0056] Step 4: Filter the Chinese medicine in step 3, add 7-9 times the total weight of the medicine into water and boil for 1 hour;
[0057] In the fifth step, the three decoctions are combined, overnight, centrifuged to obtain the supernatant, and the drug solution is concentrated to a crude drug amount of 1 g / mL. After sterilization, the oral solution of the Chinese medicine composition of the present invention is prepared and refrigerated at 2-8°C for future use.
[0058] Comparative Example 1
[0059] The difference between this embodiment and embodiment 1 lies in the raw materials, which are made of the following raw materials in parts by weight: 26 parts of palm seeds, 5 parts of Euryale ferox, 5 parts of yam, 15 parts of Castanopsis liaoyi, 8 parts of kapok peels, 4 parts of jujubes, and 5 parts of charred hawthorn.
[0060] The preparation method of this example is referenced to Example 1.
[0061] Comparative Example 2
[0062] The difference between this embodiment and embodiment 1 lies in the raw materials, which are made of the following raw materials in parts by weight: 13 parts of Rheum officinale thorns, 8 parts of palm seeds, 13 parts of knotweed flowers, 5 parts of Euryale ferox, 10 parts of yam, 5 parts of Liaowasong, 8 parts of kapok peels, 4 parts of jujubes, and 10 parts of charred hawthorns.
[0063] The preparation method of this example is referenced to Example 1.
[0064] Comparative Example 3
[0065] The present embodiment differs from the first embodiment in the raw materials. The gorgon fruit is replaced with lotus seed, and the present embodiment is prepared from the following raw materials in parts by weight: 8 parts of Rheum officinale thorn, 18 parts of palm seed, 8 parts of knotweed flower, 5 parts of lotus seed, 5 parts of yam, 15 parts of Liaowasong, 8 parts of kapok peel, 4 parts of jujube, and 5 parts of charred hawthorn.
[0066] The preparation method of this example is referenced to Example 1.
[0067] Comparative Example 4
[0068] The difference between this embodiment and embodiment 1 lies in the raw materials. The Liaowasong is replaced with nutmeg and no jujube is added. The present embodiment is made of the following raw materials in parts by weight: 8 parts of Rheum officinale thorns, 18 parts of palm seeds, 8 parts of knotweed flowers, 5 parts of Euryale ferox, 5 parts of yam, 15 parts of nutmeg, 8 parts of kapok peels, and 5 parts of charred hawthorn.
[0069] The preparation method of this example is referenced to Example 1.
[0070] Test Example 1
[0071] Acute toxicity test of the Chinese medicine composition of the present invention on mice
[0072] 1 Main materials for the test
[0073] Experimental animals: KM mice, half male and half female, weighing 18-22 g, were purchased from Weitonglihua Experimental Animal Technology Co., Ltd.
[0074] Test sample: the Chinese medicine preparation prepared in Example 1 of the present invention.
[0075] 2 Test methods
[0076] The mice that had been temporarily housed for 3 days were randomly divided into 2 groups according to gender, with 20 mice in each group (half female). Before the test, the mice in each group were fasted but not watered for 12 hours, and the mice in the drug administration group were intragastrically administered with the suspension of the Chinese medicine preparation prepared in Example 1 at a dose of 5 g / kg.bw, and the mice in the control group were intragastrically administered with an equal amount of normal saline at a dose of 20 mL / kg.bw, twice a day in the morning and afternoon, and observed continuously for 14 days after administration, and the toxic reactions and deaths of the mice were recorded.
[0077] 3 Test results
[0078] The results showed that there were no significant differences in the feeding and drinking, weight gain, morphological appearance and behavioral activities of the mice in the drug administration group and the control group, and no mice in each group died during the observation period after administration. This indicates that the Chinese medicine preparation of the present invention has no toxic side effects after oral administration and can be used clinically.
[0079] Test Example 2
[0080] Experimental verification of the effect of the Chinese medicine composition of the present invention on diarrhea in mice
[0081] 1 Main materials for the test
[0082] Experimental animals: KM mice, half male and half female, weighing 18-22 g, were purchased from Weitonglihua Experimental Animal Technology Co., Ltd.
[0083] Test samples: the Chinese medicine preparations prepared in Examples 1-5 of the present invention and Comparative Examples 1-4, senna leaf extract (raw drug concentration of 1 g / mL), and pyralidone hydrochloride capsules (Shanghai Hengshan Pharmaceutical Co., Ltd.).
[0084] 2 Test methods
[0085] The mice that had been temporarily housed for 3 days were randomly divided into 12 groups according to gender, with 20 mice in each group (half female). The Example 1-4 groups were gavaged with the suspension of the Chinese medicine preparation prepared in Examples 1-5 at a dose of 5 g / kg.bw, and the Example 5 group was gavaged with the suspension of the Chinese medicine preparation prepared in Comparative Examples 1-4 at a dose of 2 g / kg.bw; the Comparative Example 1-4 groups were gavaged with the suspension of the Chinese medicine preparation prepared in Comparative Examples 1-4 at a dose of 5 g / kg.bw; the positive drug group was gavaged with a suspension of pyralidone hydrochloride capsules at a dose of 25 mg / kg.bw; the blank group and the model group were gavaged with an equal amount of normal saline at 20 mL / kg.bw, and each group was given the drug continuously for 5 days. Before the last drug administration, they were fasted but not watered for 16 hours. After an interval of 0.5 hours, except for the blank group, which was gavaged with an equal amount of normal saline, the mice in the other groups were gavaged with 0.2 mL / mouse of senna leaf extract. The mice were placed individually in a cage covered with filter paper (such as Figure 1 , 2 ), observe and record the diarrhea of mice in each group within 6 hours. The evaluation of mouse diarrhea and feces classification are as follows: normal feces: formed feces, soft feces with formed appearance but containing water; diarrhea feces: soft feces with unformed appearance, mucous feces, and watery feces.
[0086] 3 Statistical methods
[0087] SPSS20 was used for data analysis. One-way analysis of variance was used. The data in the article were expressed as (mean ± standard deviation). P < 0.05 indicated that the difference was statistically significant.
[0088] 4 Test results
[0089] Table 1 Effects of each test group on diarrhea in mice
[0090]
[0091] Note: The data in the table are marked with *, indicating that there are significant differences compared with the model control group (P < 0.05); marked with **, indicating that there are extremely significant differences compared with the model control group (P < 0.01).
[0092] As shown in Table 1, the test groups gavaged with senna leaf extract all showed diarrhea symptoms. Compared with the model control group, the number of diarrhea in the mice in the positive drug group, Example 1 group, Example 2 group, Example 3 group, Example 4 group, Example 5 group, and Comparative Example 2 group was significantly reduced (P<0.01); compared with the model control group, the positive drug group, Example 1 group, Example 2 group, Example 3 group, Example 4 group, Example 5 group, and Comparative Example 2 group had a better effect of reducing diarrhea in mice. This shows that the Chinese medicine composition prepared by the present invention can effectively reduce the number of diarrhea in mice and can improve the diarrhea reduction rate.
[0093] Test Example 3
[0094] Experimental verification of the effect of the Chinese medicine composition of the present invention on clinical treatment of piglet diarrhea
[0095] The clinical trial was conducted at a pig farm in Lulong County, Qinhuangdao City, Hebei Province. 200 piglets with diarrhea symptoms and similar age were selected and divided into 4 groups, 50 in each group. The blank control group was fed normally without adding any drugs. Group 1 of the experiment used the drug prepared in Example 1 and administered it at 0.2% mixed with feed; Group 2 of the experiment used the drug prepared in Example 3 and administered it at 0.2% mixed with feed; Group 3 of the experiment used the drug prepared in Comparative Example 2 and administered it at 0.2% mixed with feed; the drug was administered continuously for 5 days. In the clinical trial, if the piglets refused to eat (surrounded by food, sneezed), and the feeding speed slowed down, it was considered to have poor palatability. Observe and record whether the piglets have diarrhea symptoms every day, and count the cure of piglet diarrhea at the end of the experiment.
[0096] Table 2 Group design and result statistics of the experiment on the prevention of diarrhea in livestock by Chinese herbal medicine composition
[0097]
[0098] It can be concluded from the test data in Table 2 that within 5 days of the test, the cure rates of test group 1 and test group 2 were higher than those of the blank control group and test group 3, and there was no piglet refusal to eat in test group 1 and test group 2 during the test. Figure 3 , 4 The comparison is for the piglets in the test group 1 on the 5th day of administration. This indicates that the Chinese medicine composition provided by the present invention has a high cure rate for piglet diarrhea, good therapeutic effect and no palatability problem.
[0099] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention, rather than to limit it.
Claims
1. A Chinese medicine composition for preventing and treating piglet diarrhea, characterized in that: The Chinese medicine composition is composed of the following raw materials in parts by weight: 8 parts of Rheum officinale thorn, 20 parts of palm seeds, 8 parts of knotweed flower, 7 parts of Euryale ferox, 5 parts of yam, 16 parts of Liaowasong, 8 parts of kapok peel, 4 parts of jujube and 6 parts of charred hawthorn.
2. A Chinese medicine composition for preventing and treating piglet diarrhea, characterized in that: The Chinese medicine composition is composed of the following raw materials in parts by weight: 8 parts of Rheum officinale thorn, 18 parts of palm seeds, 8 parts of knotweed flowers, 5 parts of Euryale ferox, 5 parts of yam, 15 parts of Liaowasong, 8 parts of kapok peel, 4 parts of jujube and 5 parts of charred hawthorn.
3. The Chinese medicine composition according to any one of claims 1-2, characterized in that: Made into powder, oral liquid, granules, capsules or tablets.
4. The Chinese medicine composition according to claim 3, characterized in that: The dosage form is powder.
5. A method for preparing a Chinese medicine composition for preventing and treating piglet diarrhea according to any one of claims 1-2, characterized in that: The following steps are involved: The first step is to weigh the raw materials according to the weight ratio, and select, remove impurities, wash and dry the raw materials; The second step is to fully crush the above raw materials, pass them through a 80-120 mesh sieve, mix them evenly, sterilize and package them to obtain the Chinese medicine composition.
Citation Information
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