A bioreactor post-operation cleaning device
By designing a bioreactor cleaning device that includes a fixed module, an adjustment mechanism and a water and gas control mechanism, the problems of low applicability and complex operation of cleaning devices in the existing technology are solved, and efficient and convenient bioreactor cleaning and Scrape dry effect.
Patent Information
- Application Number
- CN202411239313.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-05
- Publication Date
- 2025-01-21
- Estimated Expiration
- 2044-09-05
AI Technical Summary
The existing bioreactor cleaning devices are difficult to adapt to the reactor specifications, resulting in poor cleaning results and the need for additional cleaning liquid injection devices to increase the operating burden, and manual drying increases the burden on staff.
A cleaning device including a frame, a bioreactor fixing module, a height adjustment mechanism, a thickness adjustment mechanism and a water and gas control mechanism was designed. Through these modules and mechanisms, bioreactors of different specifications can be fixed, the position of the cleaning mechanism can be adjusted to adapt to the inner and outer walls of the reactor, and the water vapor control mechanism can be used to improve the cleaning and scraping effect.
It achieves efficient cleaning of bioreactors of different specifications, reduces operating steps and staff burden, and improves cleaning and scraping effects.
Smart Images

Figure CN118751636B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of cleaning devices, in particular to a post-operation cleaning device for a bioreactor. Background Art
[0002] A photobioreactor refers to a type of device that can be used to culture photosynthetic microorganisms and their photosynthetic tissues or cells. This type of reactor has a similar structure to a general bioreactor. Under general conditions, a certain amount of light, temperature, and nutrients are required to culture the microorganisms and regulate and control the system environment. After the photosynthetic microorganism operation is completed, the photobioreactor needs to be cleaned to facilitate the next operation, so a cleaning device is required.
[0003] In the patent application with the authorization publication number CN113731992B and the authorization publication date 2021-12-31, entitled "A bioreactor post-operation cleaning device", the inner cleaning structure is provided to facilitate the cleaning of the inner wall of the bioreactor, so that the cleaning effect of the inner wall of the bioreactor is better; the outer cleaning structure is provided to facilitate the cleaning of the outer wall of the bioreactor, so that the cleaning effect of the outer wall of the bioreactor is better, and the outer cleaning structure is convenient for temporary placement to the side, does not hinder the replacement of workpieces, and is more flexible and convenient to use;
[0004] During the actual use of the above-mentioned device, the cleaning range is inconvenient to be adaptively adjusted according to the specifications of the actual bioreactor, resulting in low applicability. At the same time, the device scrapes the inner and outer walls of the bioreactor through the inner brush plate and the outer brush plate. This method is likely to cause scratches on the surface of the bioreactor. To avoid this, an additional cleaning liquid spraying device is required, which increases the operational burden. After the bioreactor is cleaned with the cleaning liquid, water droplets will be attached to the surface of the bioreactor. The presence of water droplets may provide an environment for the growth of microorganisms, which may easily affect the normal use of the bioreactor. Manual drying will increase the burden on the staff and be time-consuming and laborious.
[0005] Therefore, we propose a bioreactor post-operation cleaning device to solve the above-mentioned problems. Summary of the invention
[0006] 1. Technical problem to be solved by the invention:
[0007] The object of the present invention is to provide a bioreactor post-operation cleaning device to solve the problems in the current market raised by the above background technology.
[0008] 2. Technical solution:
[0009] To achieve the above object, the present invention provides the following technical solutions: a post-operation cleaning device for a bioreactor, comprising a frame, a bioreactor fixing module is mounted on the frame, the bioreactor fixing module comprises a lower positioning mechanism and an upper positioning mechanism, the lower positioning mechanism and the upper positioning mechanism are used for fixing the bioreactor;
[0010] A driving gear is rotatably mounted on the left side of the frame, a horizontal plate is fixed at the lower front side of the frame, a movable plate is arranged above the horizontal plate, and a height adjustment mechanism is installed between the movable plate and the horizontal plate, and the height adjustment mechanism is used to adjust the height position of the movable plate;
[0011] A cleaning mechanism is installed on the movable plate, and the cleaning mechanism includes an outer wall cleaning unit and an inner wall cleaning unit, the outer wall cleaning unit and the inner wall cleaning unit are respectively used for cleaning the inner and outer walls of the bioreactor, and a thickness adjustment mechanism is installed between the outer wall cleaning unit and the inner wall cleaning unit, and the thickness adjustment mechanism is used to adjust the distance between the outer wall cleaning unit and the inner wall cleaning unit;
[0012] A frame plate is fixed on the left side of the frame, and a water-liquid transfer chamber and a gas transfer chamber are installed on the upper front side of the frame plate, and the gas transfer chamber is located above the water-liquid transfer chamber, and a water-gas control mechanism is installed on the upper rear side of the frame plate, and the water-gas control mechanism is used to control the start and stop of the water-liquid transfer chamber and the gas transfer chamber.
[0013] Furthermore, the lower positioning mechanism includes a gear ring with a bearing installed on the frame, and a rubber pad 1 is installed on the upper end surface of the gear ring, the upper positioning mechanism includes a linear motion module fixedly installed on the upper rear side of the frame, and a base plate is fixed to the movable end of the linear motion module, and an upper top plate is rotatably installed on the side of the base plate, and a swivel is rotatably installed on the middle bearing of the upper top plate, and a rubber pad 2 is installed on the lower end of the swivel, and a flip cover mechanism is installed on the side of the base plate, and the flip cover mechanism is used to drive the upper top plate to rotate.
[0014] Through the above technical solution, the flip cover mechanism can be used to drive the upper top plate to rotate so that the bioreactor can be placed on rubber pad one, and then the upper top plate can be driven downward by the linear motion module, and the bioreactor can be fixed by the cooperation of rubber pad one and rubber pad two.
[0015] Furthermore, the flip cover mechanism includes an electric push rod fixedly mounted on the side of the base plate, a tooth plate is fixed on the output end of the electric push rod, and a force-bearing gear is meshed on the side of the tooth plate, and the force-bearing gear is fixedly mounted on the rotating shaft of the upper top plate.
[0016] Through the above technical solution, when the electric push rod is started, it can drive the toothed plate to move up and down, and the toothed plate drives the stressed gear and the upper plate to rotate by the meshing action between the stressed gears.
[0017] Furthermore, the height adjustment mechanism includes a guide rod fixed between the frame and the cross plate and a threaded rod with a bearing installed between the frame and the cross plate, a bevel gear transmission assembly is installed at the lower end of the threaded rod, and the guide rod and the movable plate form an upper and lower fitting sliding structure, and the threaded rod and the movable plate form a threaded connection.
[0018] Through the above technical solution, when the motor at the end of the bevel gear transmission assembly is started, it can drive the threaded rod to rotate, and then the movable plate moves up and down under the guidance of the guide rod.
[0019] Furthermore, the inner wall cleaning unit includes a first vertical rod fixed to the upper end of the rear side of the movable plate, a first scraper is detachably mounted on the upper end of the first vertical rod, a nozzle opening facing upward is opened on the upper end side of the first vertical rod, and an inner vertical rod is slidably mounted on the front side of the first vertical rod, and the outer wall cleaning unit includes a second vertical rod fixed to the upper end of the front side of the movable plate, an outer vertical rod is slidably mounted on the rear side of the second vertical rod, and two second scrapers are detachably mounted on the inner and outer vertical rods near the bioreactor side, and the two second scrapers are symmetrically arranged, and injection pipes are mounted on both sides of the inner and outer vertical rods, and third scrapers are clamped on the upper ends of the inner and outer vertical rods.
[0020] Through the above technical solution, the first scraper, the second scraper and the third scraper can be used to clean the inner and outer walls of the bioreactor, and the scraper can be replaced according to the specifications of the bioreactor and the use of the scraper itself.
[0021] Furthermore, the first nozzle and the second nozzle are evenly spaced on the side of the injection pipe, and the first nozzle is straight, and the outlet of the second nozzle is inclined downward, and the third nozzle is installed at the upper end of the injection pipe, and the third nozzle is a bamboo tube.
[0022] Through the above technical scheme, the second nozzle can pre-spray cleaning liquid or hot air on the bioreactor to improve the cleaning effect of the scraper on the bioreactor. The first nozzle can spray off the substances adhering to the scraper to improve the scraping effect of the scraper. The third nozzle under the bamboo tube setting can spray into the space between the two second scrapers to improve the cleaning effect.
[0023] Furthermore, the thickness adjustment mechanism includes a sliding plate that slides back and forth inside the movable plate, the sliding plate is sleeved on the outer side of the lower ends of the outer vertical rod and the inner vertical rod, and the sliding plate and the outer vertical rod and the inner vertical rod form a fitting sliding structure, and the side of the sliding plate is connected to the output end of the electric push rod 2, and the electric push rod 2 is fixedly installed on the lower front side of the movable plate, a driving motor is installed below the front side of the sliding plate, and the output end of the driving motor is keyed to a bidirectional screw at the bottom of the sliding plate, and the two ends of the bidirectional screw are respectively threadedly connected to the lower ends of the outer vertical rod and the inner vertical rod.
[0024] Through the above technical solution, when the second electric push rod is started, it can be adjusted according to the actual inner diameter of the bioreactor. After the motor drives the bidirectional screw to rotate, the second scraper on the outer vertical rod and the inner vertical rod can be driven to fit the inner and outer walls of the bioreactor respectively.
[0025] Furthermore, the water vapor control mechanism includes a driven gear mounted on a frame plate with a bearing, a turntable is provided at both upper and lower ends of the driven gear, and the turntable is rotatably mounted on the frame plate, and a ratchet assembly is installed between the two turntables and the driven gear, and a connecting rod is eccentrically mounted on the end of the turntable away from the driven gear, the ratchet assembly includes a sleeve mounted on the outer side of the driven gear shaft end and a ratchet body fixed on the driven gear shaft end, a pawl is installed between the sleeve and the ratchet body, and the ratchet teeth on the upper and lower ratchet bodies are in opposite directions.
[0026] Through the above technical solution, when the driven gear rotates in positive and negative directions, under the action of the ratchet assembly, the upper and lower turntables can be driven to rotate respectively.
[0027] Furthermore, a piston plate is slidably mounted inside the water-liquid transfer chamber and the gas transfer chamber, and the side of the piston plate is rotatably connected to the end of the connecting rod, and two one-way valves in opposite directions are installed on the water-liquid transfer chamber and the gas transfer chamber, and the water-liquid transfer chamber is connected to the water outlet of the cleaning liquid tank and the injection pipe on the right side through the two one-way valves and the hose, respectively, while the gas transfer chamber is connected to the outside and the injection pipe on the left side through the two one-way valves and the hose, respectively, and a heating element is installed inside the gas transfer chamber.
[0028] Through the above technical scheme, when the two piston plates reciprocate inside the water transfer chamber and the gas transfer chamber respectively, the piston plate in the water transfer chamber can inject the cleaning liquid in the cleaning liquid tank into the injection pipe, and the piston plate in the gas transfer chamber can heat the outside air and pass it into the other injection pipe, so as to cooperate with the scraper to perform cleaning operations and improve the cleaning effect.
[0029] Furthermore, the driving gear, the gear ring and the driven gear all form a meshing structure.
[0030] Through the above technical solution, when the driving gear rotates, the gear ring and the driven gear can be driven to rotate synchronously.
[0031] 3. Beneficial effects:
[0032] By adopting the technical solution provided by the present invention, compared with the prior art, the post-operation cleaning device of the bioreactor of the present invention is convenient for fixing bioreactors of different specifications through the bioreactor fixing module, and at the same time, the height adjustment mechanism and the thickness adjustment mechanism are convenient for adjusting the position of the cleaning mechanism, so that the cleaning mechanism cleans the inner and outer walls of the bioreactor, and under the cooperation of the water and gas control mechanism, the cleaning effect and the subsequent scraping effect are improved. The specific contents are as follows:
[0033] Start the electric push rod 1 to drive the tooth plate to move. The tooth plate drives the upper top plate to rotate by meshing with the stressed gear, so as to facilitate the bioreactor to be placed upside down and centered on the rubber pad 1. Then start the electric push rod 1 in the reverse direction to drive the upper top plate to rotate in the reverse direction. Then, the upper top plate is driven downward by the linear motion module until the rubber pad 2 is attached to the upper end surface of the bioreactor. Under the action of the upper and lower rubber pads 1 and 2, the bioreactor can realize the fixing operation of bioreactors of different specifications.
[0034] The motor at the end of the bevel gear transmission assembly is started to drive the threaded rod connected to the bevel gear transmission assembly to rotate, and the movable plate sleeved on the outer side of the threaded rod moves up and down under the action of the guide rod, thereby driving the cleaning mechanism on the movable plate to move up and down synchronously, so as to facilitate adaptive adjustment according to bioreactors of different heights, and the second electric push rod is started to drive the sliding plate to move, and then the driving motor is started, and the driving motor drives the bidirectional screw to rotate, and the outer vertical rod and the inner vertical rod threadedly sleeved on both ends of the bidirectional screw move relatively until the second scraper on the outer vertical rod and the inner vertical rod are respectively attached to the inner and outer walls of the bioreactor, so as to be suitable for bioreactors with different inner and outer diameters, and the motor at the end of the driving gear is started to drive the driving gear to rotate, and the driving gear drives the bioreactor above the gear ring to rotate by meshing with the gear ring, and the cleaning mechanism is used to clean the bioreactor during its rotation;
[0035] When the motor at the end of the driving gear drives the driving gear to rotate, the driving gear utilizes the meshing action with the gear ring and the driven gear to drive the gear ring and the driven gear to rotate synchronously. When the driving gear rotates forward, the driven gear utilizes the ratchet assembly to drive the turntable located below to rotate. After the turntable below rotates, the connecting rod between the piston plate inside the water transfer chamber drives the piston plate to reciprocate in the water transfer chamber, and the cleaning liquid in the cleaning liquid tank is drawn into the water transfer chamber, and then squeezed into the injection pipe located on the right side, and then sprayed out from the first nozzle, the second nozzle and the third nozzle. The first nozzle blows toward the surface of the second scraper to remove impurities adhered to the second scraper. The second nozzle blows toward the bioreactor so that the second scraper can scrape off the impurities on the bioreactor. The third nozzle blows between the two second scrapers to improve the cleaning effect.
[0036] When cleaning is completed, the motor at the end of the driving gear is started in reverse to drive the driving gear to rotate in the opposite direction. The driven gear uses the ratchet assembly to drive the turntable located above to rotate. When the turntable located above rotates, according to the above working principle, the gas transfer chamber filters and extracts external air, heats it through the heating element, and then squeezes it into the injection pipe located on the left, and then sprays it out from the first nozzle, the second nozzle and the third nozzle. At the same time, the driving gear drives the bioreactor to rotate in the opposite direction, so that the second scraper on the other side can scrape off the water droplets on the surface of the bioreactor. At the same time, since the hot air is sprayed from the first nozzle, the second nozzle and the third nozzle, the effect of removing the water droplets on the surface of the bioreactor can be improved. BRIEF DESCRIPTION OF THE DRAWINGS
[0037] Figure 1 It is a schematic diagram of the three-dimensional structure when the present invention is working from a side view;
[0038] Figure 2 It is a schematic diagram of the three-dimensional structure of the present invention when it is not working;
[0039] Figure 3 This is a schematic diagram of the three-dimensional structure of the bioreactor fixing module of the present invention from a side view;
[0040] Figure 4 This is a schematic diagram of the three-dimensional structure of the upper top plate of the present invention from a side view;
[0041] Figure 5 It is a schematic diagram of the three-dimensional structure of the cleaning mechanism of the present invention from a side view;
[0042] Figure 6 It is a schematic diagram of the three-dimensional structure of the cleaning mechanism of the present invention from a side view;
[0043] Figure 7 This is a schematic diagram of the three-dimensional structure of the inner vertical rod of the present invention from a side view;
[0044] Figure 8 For the present invention Figure 7The enlarged structural diagram at A in the middle;
[0045] Fig. 9 It is a schematic diagram of the three-dimensional structure of the present invention when it is not working from another side angle;
[0046] Fig.10 It is a schematic diagram of the three-dimensional structure of the frame plate of the present invention;
[0047] Fig.11 It is a schematic diagram of the three-dimensional structure of the ratchet assembly of the present invention in side section.
[0048] In the figure: 1, frame; 2, gear ring; 21, rubber pad 1; 3, driving gear; 4, linear motion module; 5, base plate; 6, top plate; 61, swivel; 62, rubber pad 2; 7, flip cover mechanism; 71, electric push rod 1; 72, gear plate; 73, force gear; 8, horizontal plate; 9, height adjustment mechanism; 91, guide rod; 92, threaded rod; 93, bevel gear transmission assembly; 10, movable plate; 11, cleaning mechanism; 111, first vertical rod; 1111, first scraper; 112, second vertical rod; 113, outer vertical rod; 114, inner vertical rod; 115, second Scraper; 116, injection pipe; 1161, first nozzle; 1162, second nozzle; 1163, third nozzle; 117, third scraper; 12, thickness adjustment mechanism; 121, sliding plate; 122, bidirectional screw; 123, drive motor; 124, electric push rod 2; 13, frame plate; 14, water and gas control mechanism; 141, driven gear; 142, turntable; 143, ratchet assembly; 1431, sleeve disc; 1432, ratchet body; 1433, pawl; 144, connecting rod; 15, water transfer chamber; 16, gas transfer chamber; 17, piston plate. DETAILED DESCRIPTION
[0049] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0050] Example:
[0051] See also Figure 1-11The present invention provides a technical solution: a bioreactor post-operation cleaning device, comprising a frame 1, a bioreactor fixing module is installed on the frame 1, the bioreactor fixing module comprises a lower positioning mechanism and an upper positioning mechanism, the lower positioning mechanism and the upper positioning mechanism are used for fixing the bioreactor; the lower positioning mechanism comprises a gear ring 2 mounted on the frame 1 by a bearing, and a rubber pad 21 is installed on the upper end surface of the gear ring 2, the upper positioning mechanism comprises a linear motion module 4 fixedly mounted on the upper rear side of the frame 1, and the movable end of the linear motion module 4 is fixedly mounted on the upper rear side of the frame 1. A base plate 5 is fixed, and an upper plate 6 is rotatably mounted on the side of the base plate 5, and a rotating ring 61 is rotatably mounted on the middle bearing of the upper plate 6, and a rubber pad 62 is mounted on the lower end of the rotating ring 61, and a flip cover mechanism 7 is mounted on the side of the base plate 5, and the flip cover mechanism 7 is used to drive the upper plate 6 to rotate; the flip cover mechanism 7 includes an electric push rod 71 fixedly mounted on the side of the base plate 5, and a tooth plate 72 is fixedly mounted on the output end of the electric push rod 71, and a force gear 73 is meshed on the side of the tooth plate 72, and the force gear 73 is fixedly mounted on the rotating shaft of the upper plate 6;
[0052] Start the electric push rod 1 71 to drive the tooth plate 72 to move. The tooth plate 72 drives the force gear 73 and the upper top plate 6 to rotate by meshing with the force gear 73, so as to facilitate the bioreactor to be placed upside down and centered on the rubber pad 1 21. Then, start the electric push rod 1 71 in the reverse direction to drive the upper top plate 6 to rotate in the reverse direction to restore the original state. Then, the upper top plate 6 is driven downward by the linear motion module 4 until the rubber pad 2 62 is attached to the upper end surface of the bioreactor. Under the action of the upper and lower rubber pads 1 21 and the rubber pad 2 62, the bioreactor can achieve the fixing operation of bioreactors of different specifications.
[0053] A driving gear 3 is rotatably mounted on the left side of the frame 1, and a transverse plate 8 is fixed at the lower front side of the frame 1, and a movable plate 10 is arranged above the transverse plate 8, and a height adjustment mechanism 9 is installed between the movable plate 10 and the transverse plate 8, and the height adjustment mechanism 9 is used to adjust the height position of the movable plate 10; the height adjustment mechanism 9 includes a guide rod 91 fixed between the frame 1 and the transverse plate 8 and a threaded rod 92 with a bearing installed between the frame 1 and the transverse plate 8, a bevel gear transmission assembly 93 is installed at the lower end of the threaded rod 92, and the guide rod 91 and the movable plate 10 form an upper and lower fitting sliding structure, and the threaded rod 92 and the movable plate 10 form a threaded connection;
[0054] Connect one end of the bevel gear transmission assembly 93 to the output end of the motor, and then start the motor at the end of the bevel gear transmission assembly 93 to drive the threaded rod 92 connected to the bevel gear transmission assembly 93 to rotate, and the movable plate 10 sleeved on the outer side of the threaded rod 92 moves up and down under the action of the guide rod 91, thereby driving the cleaning mechanism 11 on the movable plate 10 to move up and down synchronously, so as to facilitate adaptive adjustment according to bioreactors of different heights;
[0055] A cleaning mechanism 11 is installed on the movable plate 10, and the cleaning mechanism 11 includes an outer wall cleaning unit and an inner wall cleaning unit, the outer wall cleaning unit and the inner wall cleaning unit are respectively used for cleaning the inner and outer walls of the bioreactor, and a thickness adjustment mechanism 12 is installed between the outer wall cleaning unit and the inner wall cleaning unit, and the thickness adjustment mechanism 12 is used to adjust the distance between the outer wall cleaning unit and the inner wall cleaning unit; the inner wall cleaning unit includes a first vertical rod 111 fixed to the upper end of the rear side of the movable plate 10, and the upper end of the first vertical rod 111 is detachably mounted with a first scraper 1111, and the first vertical rod 11 1 is provided with a nozzle opening upward, and an inner vertical rod 114 is slidably mounted on the front side of the first vertical rod 111, the outer wall cleaning unit comprises a second vertical rod 112 fixed to the upper end of the front side of the movable plate 10, an outer vertical rod 113 is slidably mounted on the rear side of the second vertical rod 112, and two second scrapers 115 are detachably mounted on the inner vertical rod 114 and the outer vertical rod 113 near the bioreactor, and the two second scrapers 115 are symmetrically arranged, and both sides of the inner vertical rod 114 and the outer vertical rod 113 are equipped with injection pipes 116, and the inner vertical rod 114 and the outer vertical rod 113 are detachably mounted on the rear side of the movable plate 10, and the inner vertical rod 114 and the outer vertical rod 113 are detachably mounted on the rear side of the movable plate 10, and the inner vertical rod 114 and the outer vertical rod 113 are detachably mounted on the rear side of the movable plate 10, and the inner vertical rod 114 and the outer vertical rod 113 are symmetrically arranged ... 3 are all clamped with a third scraper 117; the side of the injection pipe 116 is evenly spaced with a first nozzle 1161 and a second nozzle 1162, and the first nozzle 1161 is straight, and the second nozzle 1162 is inclined downward, and the upper end of the injection pipe 116 is installed with a third nozzle 1163, and the third nozzle 1163 is a bamboo tube; the thickness adjustment mechanism 12 includes a sliding plate 121 that slides back and forth inside the movable plate 10, and the sliding plate 121 is sleeved on the outer side of the lower end of the outer vertical rod 113 and the inner vertical rod 114, and the sliding plate 121 is connected to the outer vertical rod 1 13 and the inner vertical rod 114 form a fitting sliding structure, and the side of the sliding plate 121 is connected to the output end of the electric push rod 124, and the electric push rod 124 is fixedly installed on the lower front side of the movable plate 10, and a driving motor 123 is installed on the lower front side of the sliding plate 121, and the output end of the driving motor 123 is keyed to a bidirectional screw rod 122 at the lower side of the sliding plate 121, and the two ends of the bidirectional screw rod 122 are respectively threadedly connected with the lower ends of the outer vertical rod 113 and the inner vertical rod 114; the driving gear 3 and the gear ring 2 and the driven gear 141 all form a meshing structure;
[0056] The second electric push rod 124 is started to drive the sliding plate 121 to move, and then the driving motor 123 is started. The driving motor 123 drives the bidirectional screw 122 to rotate, and the outer vertical rod 113 and the inner vertical rod 114 threadedly sleeved on both ends of the bidirectional screw 122 move relatively until the second scraper 115 on the outer vertical rod 113 and the inner vertical rod 114 are respectively attached to the inner and outer walls of the bioreactor, so as to be suitable for bioreactors with different inner and outer diameters. The motor at the end of the driving gear 3 is started to drive the driving gear 3 to rotate. The driving gear 3 drives the bioreactor above the gear ring 2 to rotate by meshing with the gear ring 2. During the rotation of the bioreactor, the cleaning mechanism 11 is used to clean it;
[0057] A frame plate 13 is fixed to the left side of the frame 1, and a water-liquid transfer chamber 15 and a gas transfer chamber 16 are installed on the upper front side of the frame plate 13, and the gas transfer chamber 16 is located above the water-liquid transfer chamber 15, and a water-gas control mechanism 14 is installed on the upper rear side of the frame plate 13, and the water-gas control mechanism 14 is used to control the start and stop of the water-liquid transfer chamber 15 and the gas transfer chamber 16; the water-gas control mechanism 14 includes a driven gear 141 mounted on the frame plate 13 by a bearing, and a turntable 142 is provided at both upper and lower ends of the driven gear 141, and the turntable 142 is rotatably mounted on the frame plate 13, and a ratchet assembly 143 is installed between the two turntables 142 and the driven gear 141, and a connecting rod 144 is eccentrically rotatably installed at the end of the turntable 142 away from the driven gear 141, and the ratchet assembly 143 includes a connecting rod 144 sleeved on the outer side of the shaft end of the driven gear 141 The sleeve 1431 and the ratchet body 1432 fixed on the shaft end of the driven gear 141, a pawl 1433 is installed between the sleeve 1431 and the ratchet body 1432, and the ratchet teeth on the upper and lower ratchet bodies 1432 are in opposite directions; the piston plate 17 is fitted and slidably installed inside the water transfer chamber 15 and the gas transfer chamber 16, and the side of the piston plate 17 is rotatably connected with the end of the connecting rod 144, and two one-way valves with opposite directions are installed on the water transfer chamber 15 and the gas transfer chamber 16, and the water transfer chamber 15 is connected to the water outlet of the cleaning liquid tank and the injection pipe 116 on the right side through the two one-way valves and the hose, and the gas transfer chamber 16 is connected to the outside and the injection pipe 116 on the left side through the two one-way valves and the hose, and a heating element is installed inside the gas transfer chamber 16;
[0058] When the motor at the end of the driving gear 3 drives the driving gear 3 to rotate, the driving gear 3 utilizes the meshing action with the gear ring 2 and the driven gear 141 to drive the gear ring 2 and the driven gear 141 to rotate synchronously. When the driving gear 3 rotates forward, the driven gear 141 drives the rotating disk 142 located below to rotate by using the ratchet assembly 143. After the rotating disk 142 below rotates, the connecting rod 144 between the piston plate 17 inside the water transfer chamber 15 drives the piston plate 17 to reciprocate in the water transfer chamber 15 to transfer the cleaning liquid. The cleaning liquid in the box is drawn into the water transfer chamber 15, and then squeezed into the injection pipe 116 located on the right side, and then ejected from the first injection pipe 1161, the second injection pipe 1162 and the third injection pipe 1163. The first injection pipe 1161 blows toward the surface of the second scraper 115 to remove impurities adhering to the second scraper 115, and the second injection pipe 1162 blows toward the bioreactor so that the second scraper 115 can scrape off the impurities on the bioreactor. The third injection pipe 1163 blows between the two second scrapers 115 to improve the cleaning effect.
[0059] When cleaning is completed, the motor at the end of the driving gear 3 is started in reverse to drive the driving gear 3 to rotate in the opposite direction. The driven gear 141 uses the ratchet assembly 143 to drive the turntable 142 located above to rotate. When the turntable 142 located above rotates, according to the above working principle, the gas transfer chamber 16 filters and extracts external air, heats it through the heating element, and then squeezes it into the injection pipe 116 located on the left, and then sprays it out through the first nozzle 1161, the second nozzle 1162 and the third nozzle 1163. At the same time, the driving gear 3 drives the bioreactor to rotate in the opposite direction, so that the second scraper 115 on the other side can scrape off the water droplets on the surface of the bioreactor. At the same time, since the hot air is sprayed from the first nozzle 1161, the second nozzle 1162 and the third nozzle 1163, the effect of removing the water droplets on the surface of the bioreactor can be improved.
[0060] Working principle: When cleaning the device after using the bioreactor, Figure 1-11 As shown, firstly, the water transfer chamber 15 is connected to the injection pipe 116 and the cleaning liquid tank on the right side by a hose, and the gas transfer chamber 16 is connected to the injection pipe 116 on the left side by a hose, and then the upper top plate 6 is rotated by the flip cover mechanism 7 so that the bioreactor is placed upside down and centered, and then the bioreactor is fixed by the lower positioning mechanism and the upper positioning mechanism;
[0061] Then, the height adjustment mechanism 9 and the thickness adjustment mechanism 12 are used to adjust the position of the cleaning mechanism 11 until the scraper is attached to the inner and outer walls of the bioreactor, and then the motor at the end of the drive gear 3 is started to drive the bioreactor to rotate. During the rotation process, the scraper is used to clean the bioreactor;
[0062] During the rotation of the driving gear 3, the cooperation between the water vapor control mechanism 14 and the turntable 142 located below is used to drive the piston plate 17 to reciprocate inside the water transfer chamber 15, and the cleaning liquid in the cleaning liquid tank is sprayed out through the injection pipe 116 located on the right, and the contact effect of the scraper is cooperated to improve the cleaning effect. When the cleaning operation is completed, the motor at the end of the driving gear 3 is started in reverse to drive the driving gear 3 to rotate in the opposite direction, and the cooperation between the water vapor control mechanism 14 and the turntable 142 located above is used to drive the piston plate 17 to reciprocate inside the gas transfer chamber 16, and then the heated external gas is blown to the surface of the bioreactor to scrape off the water droplets on the surface of the bioreactor.
[0063] The contents not described in detail in this specification belong to the prior art known to professional and technical personnel in this field.
[0064] In the description of the present invention, unless otherwise specified, "plurality" means two or more than two; the orientations or positional relationships indicated by the terms "upper", "lower", "left", "right", "inner", "outer", "front end", "rear end", "head", "tail", etc. are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", "third", etc. are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.
[0065] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "connected" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0066] Although the present invention has been described in detail with reference to the aforementioned embodiments, it is still possible for those skilled in the art to modify the technical solutions described in the aforementioned embodiments, or to make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.
Claims
1. A post-operation cleaning device for a bioreactor, characterized in that: It comprises a frame (1), on which a bioreactor fixing module is mounted, the bioreactor fixing module comprising a lower positioning mechanism and an upper positioning mechanism, the lower positioning mechanism and the upper positioning mechanism being used for fixing the bioreactor; A driving gear (3) is rotatably mounted on the left side of the frame (1), a transverse plate (8) is fixed at the lower front side of the frame (1), a movable plate (10) is arranged above the transverse plate (8), and a height adjustment mechanism (9) is installed between the movable plate (10) and the transverse plate (8), the height adjustment mechanism (9) being used to adjust the height position of the movable plate (10); A cleaning mechanism (11) is installed on the movable plate (10), and the cleaning mechanism (11) comprises an outer wall cleaning unit and an inner wall cleaning unit, the outer wall cleaning unit and the inner wall cleaning unit are respectively used for cleaning the inner and outer walls of the bioreactor, and a thickness adjustment mechanism (12) is installed between the outer wall cleaning unit and the inner wall cleaning unit, and the thickness adjustment mechanism (12) is used to adjust the distance between the outer wall cleaning unit and the inner wall cleaning unit; A frame plate (13) is fixed on the left side of the frame (1), and a water-liquid transfer chamber (15) and a gas transfer chamber (16) are installed on the upper front side of the frame plate (13), and the gas transfer chamber (16) is located above the water-liquid transfer chamber (15). A water-gas control mechanism (14) is installed on the upper rear side of the frame plate (13), and the water-gas control mechanism (14) is used to control the start and stop of the water-liquid transfer chamber (15) and the gas transfer chamber (16); The water vapor control mechanism (14) comprises a driven gear (141) mounted on a frame plate (13) by a bearing, a rotating disk (142) is provided at both upper and lower ends of the driven gear (141), and the rotating disk (142) is rotatably mounted on the frame plate (13), and a ratchet assembly (143) is installed between the two rotating disks (142) and the driven gear (141), and a connecting rod (144) is eccentrically rotatably installed at the end of the rotating disk (142) away from the driven gear (141), and the ratchet assembly (143) comprises a sleeve (1431) sleeved on the outer side of the shaft end of the driven gear (141) and a ratchet body (1432) fixed on the shaft end of the driven gear (141), a ratchet pawl (1433) is installed between the sleeve (1431) and the ratchet body (1432), and the ratchet teeth on the upper and lower ratchet bodies (1432) are in opposite directions; The water transfer chamber (15) and the gas transfer chamber (16) are both fitted with a piston plate (17) for sliding installation, and the side of the piston plate (17) is rotatably connected to the end of the connecting rod (144), and the water transfer chamber (15) and the gas transfer chamber (16) are both installed with two one-way valves in opposite directions, and the water transfer chamber (15) is connected to the water outlet of the cleaning liquid tank and the injection pipe (116) located on the right side through the two one-way valves and a hose, respectively, and the gas transfer chamber (16) is connected to the outside and the injection pipe (116) located on the left side through the two one-way valves and a hose, respectively, and a heating element is installed inside the gas transfer chamber (16); The lower positioning mechanism comprises a gear ring (2) mounted on a frame (1) by a bearing, the driving gear (3) and the gear ring (2) forming a meshing structure, and the driving gear (3) and the driven gear (141) forming a meshing structure, and the driving gear (3) drives the bioreactor above the gear ring (2) to rotate by means of the meshing action with the gear ring (2); The inner wall cleaning unit comprises a first vertical rod (111) fixed to the upper end of the rear side of the movable plate (10), a first scraper (1111) being detachably mounted on the upper end of the first vertical rod (111), a nozzle opening facing upwards being provided on the upper end side of the first vertical rod (111), and an inner vertical rod (114) being slidably mounted on the front side of the first vertical rod (111), and the outer wall cleaning unit comprises a second vertical rod (112) fixed to the upper end of the front side of the movable plate (10), and the second vertical rod An outer vertical rod (113) is slidably mounted on the rear side of (112), and two second scrapers (115) are detachably mounted on the inner vertical rod (114) and the outer vertical rod (113) near the bioreactor, and the two second scrapers (115) are symmetrically arranged, and injection pipes (116) are mounted on both sides of the inner vertical rod (114) and the outer vertical rod (113), and third scrapers (117) are clamped on the upper ends of the inner vertical rod (114) and the outer vertical rod (113).
2. A bioreactor post-operation cleaning device according to claim 1, characterized in that: The upper end surface of the gear ring (2) is provided with a rubber pad 1 (21), the upper positioning mechanism comprises a linear motion module (4) fixedly mounted on the upper rear side of the frame (1), the movable end of the linear motion module (4) is fixed with a base plate (5), an upper top plate (6) is rotatably mounted on the side of the base plate (5), a swivel ring (61) is rotatably mounted on the middle bearing of the upper top plate (6), and a rubber pad 2 (62) is mounted on the lower end of the swivel ring (61), and a flip cover mechanism (7) is mounted on the side of the base plate (5), and the flip cover mechanism (7) is used to drive the upper top plate (6) to rotate.
3. A bioreactor post-operation cleaning device according to claim 2, characterized in that: The flip cover mechanism (7) comprises an electric push rod (71) fixedly mounted on the side of the base plate (5); a toothed plate (72) is fixedly mounted on the output end of the electric push rod (71); a force-bearing gear (73) is meshed on the side of the toothed plate (72); and the force-bearing gear (73) is fixedly mounted on the rotating shaft of the upper top plate (6).
4. A bioreactor post-operation cleaning device according to claim 1, characterized in that: The height adjustment mechanism (9) comprises a guide rod (91) fixed between the frame (1) and the cross plate (8) and a threaded rod (92) with a bearing installed between the frame (1) and the cross plate (8); a bevel gear transmission assembly (93) is installed at the lower end of the threaded rod (92); the guide rod (91) and the movable plate (10) form an upper and lower fitting sliding structure, and the threaded rod (92) and the movable plate (10) form a threaded connection.
5. A bioreactor post-operation cleaning device according to claim 1, characterized in that: A first nozzle (1161) and a second nozzle (1162) are evenly spaced on the side of the injection pipe (116), the first nozzle (1161) is straight, and the second nozzle (1162) has an outlet that is inclined downward, and a third nozzle (1163) is installed at the upper end of the injection pipe (116), and the third nozzle (1163) is a bamboo tube.
6. A bioreactor post-operation cleaning device according to claim 1, characterized in that: The thickness adjustment mechanism (12) comprises a sliding plate (121) that slides forward and backward inside the movable plate (10), the sliding plate (121) being sleeved on the outer sides of the lower ends of the outer vertical rod (113) and the inner vertical rod (114), and the sliding plate (121) and the outer vertical rod (113) and the inner vertical rod (114) forming a fitting sliding structure, and the side of the sliding plate (121) is connected to the output end of the second electric push rod (124), and the second electric push rod (124) is fixedly installed on the lower front side of the movable plate (10), a driving motor (123) is installed below the front side of the sliding plate (121), and the output end of the driving motor (123) is key-connected to a bidirectional screw rod (122) below the sliding plate (121), and the two ends of the bidirectional screw rod (122) are respectively threadedly connected to the lower ends of the outer vertical rod (113) and the inner vertical rod (114).
Citation Information
Patent Citations
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