Traditional Chinese medicine composition for treating heat stagnation constipation as well as preparation method and application of traditional Chinese medicine composition

Abstract

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating constipation and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 1-2 parts of mangnolia officinalis, 1-2 parts of pericarpium citri reticulatae, 1-2 parts of radix aucklandiae, 1-2 parts of fried betel nut, 1-2 parts of codonopsis pilosula, 1-3 parts of rheum officinale, 1-3 parts of mirabilite, 1-3 parts of rehmannia, 1-3 parts of angelica sinensis and 1-3 parts of immature bitter orange. According to the prescription, the medicine permeates corresponding acupuncture points on the body surface, continuous stimulation is achieved, and the effects of purging bowel, relaxing bowels, nourishing yin, moistening dryness, regulating qi and removing food retention are achieved. The prescription is simple in preparation process, and has the advantages of few adverse reactions, good clinical effect, suitability for large-scale production and the like in clinical use.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating heat-induced constipation and a preparation method and application thereof. Background Art

[0002] Constipation refers to a decrease in the frequency of bowel movements, generally less than 3 times a week, accompanied by difficulty in defecation and dry stools. Constipation is a common clinical disease and is generally divided into two categories, organic constipation and functional constipation. The former includes organic diseases such as rectal and anal lesions, while the latter is mainly caused by bad living habits such as bowel habits, eating habits and mental stress, and is the majority of people with constipation. Constipation is common in all populations, with an incidence rate of 2% to 28%. With age, the prevalence rate will increase significantly, especially for elderly women and pregnant women who are at high risk.

[0003] The causes of constipation are clinically divided into 1. Heat constipation: caused by heat accumulation in the stomach and intestines, which consumes body fluids. The treatment is to clear away heat and moisten the intestines. 2. Qi constipation: caused by stagnation of the liver and spleen, which leads to abnormal conduction. The treatment is to relieve qi and relieve stagnation. 3. Deficiency constipation: (1) Qi deficiency: caused by deficiency of spleen and lung qi, the large intestine is unable to conduct. The treatment is to replenish qi and moisten the intestines. (2) Blood deficiency: caused by deficiency of blood and lack of body fluids, the large intestine cannot be moistened. The treatment is to nourish blood and moisten dryness. 4. Cold constipation: caused by deficiency of yang qi, the intestinal transmission is unable. The treatment is to warm yang and relieve constipation.

[0004] In modern treatment, Western medicine mainly uses osmotic drugs such as lactulose and polyethylene glycol; volumetric drugs such as polycarbophil calcium and wheat cellulose; irritant drugs such as senna and anthraquinones. Long-term use of such drugs has many adverse reactions, and is prone to dependence and affects the absorption of calcium, phosphorus and fat-soluble vitamins. Long-term use of irritant laxatives can also cause irreversible intestinal nerve damage. In addition, taking Western medicine regardless of the cause of the disease has the disadvantages of treating the symptoms but not the root cause, unstable efficacy, and reversal after stopping the drug. Summary of the invention

[0005] The present invention aims to overcome the deficiencies of the prior art and provides an external Chinese medicine composition for treating heat-induced constipation and a preparation method and application thereof.

[0006] One of the purposes of the present invention is to provide a Chinese medicine composition for treating heat-induced constipation.

[0007] The object of the present invention is achieved through the following technical solutions: Rhubarb is bitter and cold, can clear heat and relieve constipation, and can cleanse the gastrointestinal heat and stagnation, so it is the main medicine; Glauber's salt is salty and cold, can clear heat and relieve constipation, soften hard masses and moisten dryness, and can remove dryness and stagnation, so it is the assistant medicine. The combination of Glauber's salt and rhubarb can significantly enhance the therapeutic effect of attacking and purging heat. It can effectively improve the problem of gastrointestinal stagnation, promote gastrointestinal peristalsis, and excrete toxic substances from the body; inhibit bacterial growth, effectively prevent Escherichia coli from eroding the human body, and reduce urea synthesis; relieve abdominal pain symptoms, effectively reduce the pressure in the pancreatic duct, and relax the sphincter; at the same time, it can eliminate inflammation in the body and prevent infection. With raw rehmannia to clear heat and cool blood, nourish yin and produce body fluid; angelica to nourish blood, activate blood circulation and moisten intestines, it is often used for constipation caused by blood deficiency and dry intestines; Zhishi to break up qi and eliminate stagnation; Magnolia officinalis to promote qi and eliminate stagnation, widen the intestines and relieve qi, eliminate lumps and distension; Tangerine peel to regulate qi and regulate the middle; Aucklandia to promote qi and relieve pain, it is used to treat damp-heat diarrhea, tenesmus, and can also treat abdominal distension and pain and constipation caused by food stagnation, and is often used with rhubarb and betel nut; fried betel nut to eliminate stagnation, promote qi and promote diuresis, arecoline has a cholinergic effect, can excite cholinergic receptors and increase intestinal peristalsis. "Compendium of Materia Medica" records that "it can treat heaviness after diarrhea, various pains in the heart and abdomen, constipation, phlegm and shortness of breath. It can treat malaria and prevent malaria"; multiple drugs are used together to promote qi and disperse stagnation, eliminate lumps and distension, and eliminate fullness; Codonopsis to nourish the middle and replenish qi, promote body fluid, nourish blood and moisten dryness. The whole prescription plays the role of relieving bowels and relieving constipation, nourishing yin and moistening dryness, and regulating qi and eliminating stagnation.

[0008] To achieve the above object, the present invention provides the following solutions: The invention provides a traditional Chinese medicine composition for treating heat-accumulation constipation. The traditional Chinese medicine composition comprises the following components by weight: 1-2 parts of magnolia bark, 1-2 parts of dried tangerine peel, 1-2 parts of costusroot, 1-2 parts of fried betel nut, 1-2 parts of codonopsis pilosula, 1-3 parts of rhubarb, 1-3 parts of sodium sulfate, 1-3 parts of rehmannia root, 1-3 parts of angelica sinensis, and 1-3 parts of immature bitter orange.

[0009] Preferably, by weight, 1 part of Magnolia officinalis, 1 part of dried tangerine peel, 1 part of costus root, 1 part of fried betel nut, 1 part of Codonopsis pilosula, 2 parts of rhubarb, 2 parts of Sodium sulfate, 2 parts of Rehmannia root, 2 parts of Angelica sinensis, and 2 parts of Citrus aurantium.

[0010] Preferably, by weight, 1 part of Magnolia officinalis, 1 part of dried tangerine peel, 1 part of costus root, 1 part of fried betel nut, 1 part of Codonopsis pilosula, 3 parts of rhubarb, 3 parts of sodium sulfate, 3 parts of Rehmannia root, 3 parts of Angelica sinensis, and 3 parts of Citrus aurantium.

[0011] Preferably, by weight, 2 parts of Magnolia officinalis, 2 parts of dried tangerine peel, 2 parts of costusroot, 2 parts of fried betel nut, 2 parts of Codonopsis pilosula, 2 parts of rhubarb, 2 parts of Sodium sulfate, 2 parts of Rehmannia root, 2 parts of Angelica sinensis, and 2 parts of Citrus aurantium.

[0012] The second object of the present invention is to provide a method for preparing the above-mentioned Chinese medicine composition, comprising the following steps: S1 weighs a certain amount of Magnolia officinalis, dried orange peel, costusroot, fried betel nut, Codonopsis pilosula, rhubarb, sodium sulfate, Rehmannia root, Chinese angelica root, and Citrus aurantium; S2 crushes the above raw materials into fine powder and passes through a 80-200 mesh sieve; S3: adding a pharmaceutically acceptable excipient to the above-mentioned fine powder, blending into a paste, and preparing an ointment or a paste; S4 takes an appropriate amount of paste and puts it on the empty patch to obtain an acupoint patch.

[0013] Preferably, the excipients of the traditional Chinese medicine composition for treating heat-induced constipation include, but are not limited to, pharmaceutically acceptable excipients such as water, vinegar, honey, and vaseline.

[0014] Preferably, the fine powder is 1 part and the matrix is ​​4 parts.

[0015] The third purpose of the present invention is to use the traditional Chinese medicine composition in the treatment of heat-induced constipation.

[0016] Preferably, the Chinese medicine composition for treating heat-stagnation constipation is applied to the Shenque point.

[0017] The sources of the Chinese medicinal pieces mentioned in the above preferred implementation scheme are as follows: Magnolia officinalis: It is the dried bark, root bark and branch bark of Magnolia officinalis or Magnolia officinalis of the Magnoliaceae family. It is bitter, pungent and warm; it enters the spleen, stomach, lung and large intestine meridians. It has the effects of drying dampness and eliminating phlegm, and removing qi and distension. It is used for dampness stagnation, abdominal distension and vomiting and diarrhea, food stagnation and qi stagnation, abdominal distension and constipation, and phlegm and cough.

[0018] Tangerine peel: It is the dried mature peel of the citrus plant and its cultivated varieties in the Rutaceae family. Pick the mature fruits, peel the peel, and dry them in the sun or at low temperature. It is pungent, bitter, and warm; it enters the spleen and lung meridians. It has the effects of regulating qi and strengthening the spleen, drying dampness and resolving phlegm. It is used for abdominal distension, loss of appetite, vomiting and diarrhea, and cough with excessive phlegm.

[0019] Costusroot: It is the dried root of Costusroot, a plant of the Asteraceae family. It is pungent, bitter, and warm; it enters the spleen, stomach, large intestine, triple burner, and gallbladder meridians. It has the functions of promoting qi and relieving pain, strengthening the spleen and promoting digestion. It is used for chest and abdominal distension and pain, heaviness after diarrhea, indigestion, and loss of appetite.

[0020] Fried betel nut: It is the dried mature seeds of the palm plant betel nut, fried until slightly yellow. Bitter, pungent, warm; enters the stomach and large intestine meridians. It has the effects of killing insects, eliminating accumulation, promoting qi, promoting diuresis, and stopping malaria. It is used for tapeworm disease, ascariasis, ginger worm disease, abdominal pain caused by worm accumulation, diarrhea caused by accumulation, tenesmus, edema, beriberi, and malaria.

[0021] Codonopsis: It is the dried root of Codonopsis pilosula, Codonopsis pilosula or Codonopsis pilosula of Campanulaceae. It is sweet and neutral; it enters the spleen and lung meridians. It has the effects of strengthening the spleen and lungs, nourishing blood and producing body fluid. It is used for spleen and lung qi deficiency, poor appetite and fatigue, cough and asthma, qi and blood deficiency, sallow complexion, palpitations and shortness of breath, thirst due to loss of body fluid, and internal heat and thirst.

[0022] Rhubarb: The dried root and rhizome of Rheum palmatum, Rheum tangutum or Rheum officinale of the Polygonaceae family. Bitter and cold. Enters the spleen, stomach, large intestine, liver and pericardium meridians. It has the effects of purging and attacking accumulation, clearing away heat and purging fire, cooling blood and detoxifying, removing blood stasis and promoting menstruation, and removing dampness and jaundice. It is used for constipation caused by excess heat accumulation, vomiting and bleeding caused by blood heat, red eyes and swollen throat, carbuncle, abdominal pain caused by intestinal carbuncle, amenorrhea caused by blood stasis, postpartum blood stasis, traumatic injury, damp-heat dysentery, jaundice and red urine, and stranguria.

[0023] Glauber's Salt: It is a crystal made by processing and refining the sulfate mineral Glauber's Salt. It mainly contains hydrated sodium sulfate. It tastes salty, bitter and cold. It enters the stomach and large intestine meridians. It has the effects of purging and relieving constipation, moistening dryness and softening hard masses, clearing away heat and reducing swelling. It is used for excess heat stagnation, abdominal distension and pain, dry stool, intestinal carbuncle swelling and pain; external treatment of breast carbuncle, hemorrhoid swelling and pain.

[0024] Rehmannia root: fresh or dried root of Rehmannia root of the Scrophulariaceae family. Sweet, bitter, cold; enters the heart, liver, and kidney meridians. Has the effects of clearing heat and cooling blood, nourishing yin and promoting body fluid. Used for heat entering the blood, fever due to warm toxins, vomiting blood and epistaxis, yin damage due to febrile diseases, red tongue and thirst, constipation due to body fluid damage, fever due to yin deficiency, bone steaming and fatigue fever, and internal heat and thirst.

[0025] Angelica: It is the dried root of the Umbelliferae plant Angelica. It is sweet, pungent, warm, and enters the liver, heart, and spleen meridians. It has the effects of nourishing blood and activating blood circulation, regulating menstruation and relieving pain, and moistening the intestines and relieving constipation. It is used for blood deficiency and sallow complexion, dizziness and palpitations, irregular menstruation, amenorrhea and dysmenorrhea, abdominal pain due to deficiency and cold, rheumatic arthralgia, injuries from falls, carbuncle, ulcers, and constipation due to dry intestines.

[0026] Citrus aurantium: dried young fruit of the plant sour orange and its cultivated varieties or sweet orange of the Rutaceae family. Bitter, pungent, sour, slightly cold; enters the spleen and stomach meridians. It has the effects of breaking up qi and eliminating stagnation, resolving phlegm and removing lumps. It is used for stagnation of internal stagnation, fullness and pain in the lumps, heaviness after diarrhea, constipation, phlegm stagnation and qi obstruction, chest pain, chest congestion, and sagging of internal organs.

[0027] Compared with the prior art, the present invention has the following beneficial effects: The Chinese medicine composition is both attacking and replenishing, and contains tonification and replenishment, so that the replenishment is not stagnant, and the drainage is not empty. At the same time, it is used for external application to treat heat-stagnation constipation, avoiding diarrhea caused by oral medication, allowing the drug to penetrate the corresponding acupuncture points on the body surface, and continuously stimulate, achieving the effects of relieving bowels and relieving constipation, nourishing yin and moistening dryness, regulating qi and eliminating accumulation. The preparation process of the prescription is simple, and it has the advantages of few adverse reactions in clinical use, good clinical effects, and is suitable for large-scale production. . DETAILED DESCRIPTION

[0028] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0029] In order to better understand the present invention but not to limit the scope of the present invention, all the numbers expressing the amount, percentage, and other numerical values ​​used in this application should be understood to be modified by the word "about" in all cases. Each numerical parameter should at least be considered to be obtained based on the reported significant figures and by conventional rounding methods.

[0030] The present invention is further described below by way of examples, but the examples do not limit the present invention in any way.

[0031] Example 1 A Chinese medicine composition for treating heat-induced constipation and a preparation method thereof, comprising the following steps: S1 weighed Chinese herbal medicine pieces: 6g of Magnolia officinalis, 6g of Tangerine peel, 6g of Aucklandia lappa, 6g of Stir-fried Areca nut, 6g of Codonopsis pilosula, 13g of Rhubarb, 13g of Sodium Sulfate, 13g of Rehmannia glutinosa, 13g of Angelica sinensis, and 13g of Citrus aurantium; S2 crush the above raw materials through an 80-mesh sieve; S3: Add 285g of vaseline to the above-mentioned fine powder and mix into a paste to prepare a paste; S4: Take an appropriate amount of paste and place it on the empty patch to obtain the acupoint patch and apply it on the Shenque acupoint.

[0032] Example 2 A Chinese medicine composition for treating heat-induced constipation and a preparation method thereof, comprising the following steps: S1 weighed Chinese herbal medicine pieces: 6g of Magnolia officinalis, 6g of Tangerine peel, 6g of Aucklandia lappa, 6g of Stir-fried Areca nut, 6g of Codonopsis pilosula, 13g of Rhubarb, 13g of Sodium Sulfate, 13g of Rehmannia glutinosa, 13g of Angelica sinensis, and 13g of Citrus aurantium; S2 crush the above raw materials through a 100 mesh sieve; S3: Add 285g of vaseline to the above-mentioned fine powder and mix into a paste to prepare a paste; S4: Take an appropriate amount of paste and place it on the empty patch to obtain the acupoint patch and apply it on the Shenque acupoint.

[0033] Example 3 A Chinese medicine composition for treating heat-induced constipation and a preparation method thereof, comprising the following steps: S1 weighed Chinese herbal medicine pieces: 5g Magnolia officinalis, 5g Tangerine peel, 5g Aucklandia lappa, 5g Stir-fried Areca nut, 5g Codonopsis pilosula, 10g Rhubarb, 10g Sodium Sulfate, 10g Rehmannia glutinosa, 10g Angelica sinensis, 10g Citrus aurantium; S2 crush the above raw materials through an 80-mesh sieve; S3: adding 300g vaseline to the above-mentioned fine powder, mixing into a paste, and preparing an ointment; S4: Take an appropriate amount of paste and place it on the empty patch to obtain the acupoint patch and apply it on the Shenque acupoint.

[0034] Example 4 A Chinese medicine composition for treating heat-induced constipation and a preparation method thereof, comprising the following steps: S1 weighed Chinese herbal medicine pieces: 5g Magnolia officinalis, 5g Tangerine peel, 5g Aucklandia lappa, 5g Stir-fried Areca nut, 5g Codonopsis pilosula, 10g Rhubarb, 10g Sodium Sulfate, 10g Rehmannia glutinosa, 10g Angelica sinensis, 10g Citrus aurantium; S2 crush the above raw materials through a 120 mesh sieve; S3: adding 300g vaseline to the above-mentioned fine powder, mixing into a paste, and preparing an ointment; S4: Take an appropriate amount of paste and place it on the empty patch to obtain the acupoint patch and apply it on the Shenque acupoint.

[0035] Example 5 A Chinese medicine composition for treating heat-induced constipation and a preparation method thereof, comprising the following steps: S1 weighed Chinese herbal medicine pieces: 6g of Magnolia officinalis, 6g of Tangerine peel, 6g of Aucklandia lappa, 6g of Stir-fried Areca nut, 6g of Codonopsis pilosula, 13g of Rhubarb, 13g of Sodium Sulfate, 13g of Rehmannia glutinosa, 13g of Angelica sinensis, and 13g of Citrus aurantium; S2 crush the above raw materials through a 100 mesh sieve; S3: Add 280g of water to the above fine powder and mix into a paste; S4: Take an appropriate amount of paste and place it on the empty patch to obtain the acupoint patch and apply it on the Shenque acupoint.

[0036] Example 6 A Chinese medicine composition for treating heat-induced constipation and a preparation method thereof, comprising the following steps: S1 weighed Chinese herbal medicine pieces: 4g Magnolia officinalis, 4g Tangerine peel, 6g Aucklandia lappa, 6g Saussurea catechu, 6g Codonopsis pilosula, 8g Rhubarb, 8g Sodium sulfate, 12g Rehmannia root, 12g Angelica sinensis, and 12g Citrus aurantium; S2 crushes the above raw materials into fine powder and passes through a 100-mesh sieve; S3: adding 260g of Shanxi aged vinegar to the above-mentioned fine powder and blending into a paste; S4: Take an appropriate amount of paste and place it on the empty patch to obtain the acupoint patch and apply it on the Shenque acupoint.

[0037] Example 7 A Chinese medicine composition for treating heat-induced constipation and a preparation method thereof, comprising the following steps: S1 weighed Chinese herbal medicine pieces: 5g Magnolia officinalis, 5g Tangerine peel, 5g Aucklandia lappa, 5g Stir-fried Areca nut, 5g Codonopsis pilosula, 10g Rhubarb, 10g Sodium Sulfate, 10g Rehmannia glutinosa, 10g Angelica sinensis, 10g Citrus aurantium; S2 crushes the above raw materials into fine powder and passes through a 120-mesh sieve; S3: Add 200g of honey to the above fine powder and mix into a paste; S4: Take an appropriate amount of paste and place it on the empty patch to obtain the acupoint patch and apply it on the Shenque acupoint.

[0038] Example 8 A Chinese medicine composition for treating heat-induced constipation and a preparation method thereof, comprising the following steps: S1 weighed Chinese herbal medicine pieces: 5g Magnolia officinalis, 5g Tangerine peel, 5g Aucklandia lappa, 5g Stir-fried Areca nut, 5g Codonopsis pilosula, 10g Rhubarb, 10g Sodium Sulfate, 10g Rehmannia glutinosa, 10g Angelica sinensis, 10g Citrus aurantium; S2 crushes the above raw materials into very fine powder and passes through a 200-mesh sieve; S3: placing the ultrafine powder on an empty patch to obtain an acupoint patch and applying it on the Shenque acupoint.

[0039] Clinical Data Case selection: 120 patients with heat-induced constipation, including 52 males aged 25-78 years and 68 females aged 30-66 years, were randomly divided into 5 groups, with 24 patients in each group.

[0040] Drug options: Groups 1-4 were treated with the prescriptions prepared in Example 1, Example 3, Example 6 and Example 7, respectively, one patch per day, 6-8 hours each time. Group 5 was treated with: Aloe Vera Capsules (Specifications: 0.3 g / capsule. Usage and Dosage: 3 times a day, 6 capsules per time). Groups 1-4 were the treatment groups, and Shenque acupoint was applied once a day, 6-8 hours each time. Group 5 was the control group, and 6 capsules were taken 3 times a day. One month was the deadline for observation and statistics. During this period, the patient's symptoms were observed. If the symptoms disappeared completely and the patient returned to normal, the medication could be stopped.

[0041] Efficacy determination Formulated in accordance with the State Administration of Traditional Chinese Medicine's "Standards for Diagnosis and Efficacy of Traditional Chinese Medicine Diseases and Syndromes".

[0042] Cure: Defecation once within 2 days, stool becomes smooth and unobstructed, with no recurrence in the short term.

[0043] Improvement: Defecation within 3 days, smoother stools, and less smooth bowel movements.

[0044] Uncured: No improvement in symptoms.

[0045] The treatment results are shown in the table below: Number of patients / case Cured / case Improvement / case Unhealed / case Total effective rate% Control group 24 8 6 10 58.3 Example 1 24 19 3 2 91.7 Example 3 24 16 6 3 87.5 Example 6 24 17 3 4 83.3 Example 7 24 16 5 3 87.5 The above results show that the number of cured cases, the number of improved cases and the total effective rate of the Chinese medicine composition of the present invention are significantly higher than those of the control group. It can be seen that the external preparation made of the Chinese medicine composition of the present invention has a better therapeutic effect on constipation patients, a higher cure rate and a better curative effect.

[0046] Typical Cases Ms. Shen, female, 32 years old, had an average of 3-4 days of bowel movements in the past 2 years, and has not had a bowel movement for 9 days, with abdominal distension. No nausea, no vomiting, little diet, good sleep, and normal urination. Red tongue with yellow fur, and rapid pulse. Usually treated with enema. The examination diagnosis is: chronic constipation. Chinese medicine diagnosis: Yangming Fu Shi constipation. External application of the Chinese medicine composition of the present invention, once a day, one patch at a time, on the third day of treatment, the symptoms of constipation improved, and the first segment of stool was resolved within 15min. On the sixth day of treatment, defecation can be performed once every 2 days, the stool is relatively moist, the first segment of stool is resolved within 10min, and the defecation is not smooth. On the eighth day of treatment, the symptoms of constipation disappeared, defecation was performed once within 2 days, the stool was moist, the first segment of stool was resolved within 5min, and the solution was smooth. Follow-up after 1 month, maintain defecation once within 2 days, soft stool, no abdominal pain, diarrhea and other discomforts.

[0047] Mr. Ren, male, 56 years old, had constipation for 8 months, less urge to defecate, less frequent defecation, constipation, dry stool, lower abdominal distension and pain with blood in the stool, decreased appetite, bitter taste in the mouth and bad breath. Red tongue, yellow greasy fur, rapid pulse. The examination diagnosis was: chronic constipation. Chinese medicine diagnosis: constipation due to Yangming Fu Shi. External application of the Chinese medicine composition of the present invention, once a day, one patch at a time, on the first day of treatment, the patient felt that defecation was smooth, on the third day of treatment, bowel movements were maintained every day, the stool was soft, there was no abdominal pain, and the solution was smooth. Follow-up after 1 month, bowel movements were maintained once a day, the stool was soft, there was no discomfort such as abdominal pain and diarrhea, no blood in the stool occurred, and defecation was smooth.

Claims

1. A Chinese medicine composition for treating constipation, characterized in that: The invention is composed of the following raw materials and pharmaceutically acceptable carriers or excipients in parts by weight: 1-2 parts of magnolia bark, 1-2 parts of dried tangerine peel, 1-2 parts of costusroot, 1-2 parts of fried betel nut, 1-2 parts of codonopsis pilosula, 1-3 parts of rhubarb, 1-3 parts of sodium sulfate, 1-3 parts of rehmannia root, 1-3 parts of angelica sinensis and 1-3 parts of immature bitter orange.

2. The Chinese medicine composition for treating constipation according to claim 1, characterized in that: The Chinese medicine composition is prepared from the following raw materials in parts by weight: 1 part of magnolia bark, 1 part of dried tangerine peel, 1 part of costus root, 1 part of fried betel nut, 1 part of codonopsis pilosula, 2 parts of rhubarb, 2 parts of sodium sulfate, 2 parts of rehmannia root, 2 parts of angelica root, and 2 parts of immature bitter orange.

3. The Chinese medicine composition for treating constipation according to claim 1, characterized in that: The Chinese medicine composition is prepared from the following raw materials in parts by weight: 1 part of Magnolia officinalis, 1 part of Tangerine peel, 1 part of Costusroot, 1 part of Fried Areca catechu, 1 part of Codonopsis pilosula, 3 parts of Rhubarb, 3 parts of Sodium Sulfate, 3 parts of Rehmannia root, 3 parts of Angelica sinensis, and 3 parts of Citrus aurantium.

4. The Chinese medicine composition for treating constipation according to claim 1, characterized in that: The Chinese medicine composition is prepared from the following raw materials in parts by weight: 2 parts of magnolia bark, 2 parts of dried tangerine peel, 2 parts of costusroot, 2 parts of fried betel nut, 2 parts of codonopsis pilosula, 2 parts of rhubarb, 2 parts of sodium sulfate, 2 parts of rehmannia root, 2 parts of angelica sinensis, and 2 parts of immature bitter orange.

5. The Chinese medicine composition for treating constipation according to any one of claims 1 to 4, characterized in that: The dosage form of the Chinese medicine composition is ointment, paste and acupoint plaster.

6. The method for preparing the Chinese medicine composition for treating constipation according to any one of claims 1 to 4, characterized in that: The following steps are involved: S1 weighs a certain amount of Magnolia officinalis, dried orange peel, costusroot, fried betel nut, Codonopsis pilosula, rhubarb, sodium sulfate, Rehmannia root, Chinese angelica root, and immature bitter orange; S2 crushes the above raw materials into fine powder and passes through a 80-200 mesh sieve; S3: adding a pharmaceutically acceptable excipient to the above-mentioned fine powder, blending into a paste, and preparing an ointment or a paste; S4 takes an appropriate amount of paste and puts it on the empty patch to obtain an acupoint patch.

7. The method for preparing the Chinese medicine composition for treating constipation according to claim 6, characterized in that: The ratio of fine powder: matrix is ​​1-2:3-5.

8. The method for preparing the Chinese medicine composition for treating constipation according to claim 6, characterized in that: The acupuncture point is Shenque point.

9. Use of the Chinese medicine composition according to any one of claims 1 to 4 in the preparation of a drug for treating constipation.

10. The use according to claim 9, characterized in that: The constipation is functional heat-induced constipation.