Intelligent early warning system convenient for sample preservation
By installing sensors and controllers inside the ultra-low temperature refrigerator, monitoring the temperature in real time and controlling the compressor, the problem of temperature abnormality monitoring delay in the biological sample library is solved, and the samples are properly preserved and cost-reduced.
Patent Information
- Application Number
- CN202411321541.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-20
- Publication Date
- 2024-12-06
AI Technical Summary
The monitoring methods of ultra-low temperature refrigerators in the existing biological sample library are insufficient, resulting in delayed alarms when temperature abnormalities, and the sample may be damaged, and increasing sensors will take up space and increase costs.
Install sensors and controllers inside ultra-low temperature refrigerators to monitor temperature in real time and control the start and stop of the compressor, establish a data model to issue early warnings, reduce sensor use and reduce costs.
It realizes constant control of the internal temperature of ultra-low temperature refrigerators, and early warning to protect sample safety, reducing system costs and reducing sensor requirements.
Smart Images

Figure CN119085203A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of sample preservation, and in particular to an intelligent early warning system for facilitating sample preservation. Background Art
[0002] According to the definition of the Organization for Economic Cooperation and Development (OECD), a biobank is a biological application system that centrally stores various human biological materials for clinical treatment of diseases and life science research.
[0003] A biobank, also known as a biobank or sample resource library, refers to the standardized collection, processing, storage and application of samples of biological macromolecules, cells, body fluids, tissues and organs of healthy and diseased organisms, as well as clinical, pathological, treatment, follow-up, informed consent and other information related to these biological samples and their quality control, information management and application systems. It is a comprehensive resource that integrates biological sample entities, biological information, sample phenotypic data and sample research information.
[0004] In a biobank, there are usually dozens to hundreds of ultra-low temperature refrigerators running at the same time, which are responsible for storing very important biological samples. However, current monitoring methods have some shortcomings. The traditional method relies on installing a third-party sensor in the refrigerator. When the sensor detects that the temperature is out of the set range (for example, -80℃±10℃), an alarm will be sent to the monitoring system. But this method has two main problems.
[0005] First, when the sensor sounds an alarm, the temperature is often out of the safe range, which means that the sample may have been damaged. If the alarm occurs at night or on holidays, maintenance personnel cannot respond in time, and the risk of sample loss is greater. In addition, ultra-low temperature refrigerators usually use a top-down direct cooling method, and sensors are often only arranged in one position in the refrigerator. For example, if the sensor is located in the center of the refrigerator, and the refrigeration system fails and the temperature in the lower part gradually rises, the temperature of other parts may have already exceeded the safe range before the sensor detects the abnormality.
[0006] Although the monitoring accuracy can be improved by adding multiple sensors, this is not an ideal solution. First, the increase in sensors will take up valuable storage space in the refrigerator and affect the storage capacity of the samples. Second, the cost of wireless transmission sensors in low-temperature environments is very high. Using a large number of them will significantly increase the cost of the overall system, which does not meet the requirements of economical and practical use.
[0007] Therefore, an intelligent early warning system that is convenient for sample preservation is needed to solve the above problems. Summary of the invention
[0008] The purpose of the present invention is to provide an intelligent early warning system that is convenient for sample preservation and solves the above-mentioned technical problems.
[0009] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: an intelligent early warning system for facilitating sample preservation, comprising an ultra-low temperature refrigerator, the ultra-low temperature refrigerator comprising a compressor and a door, a plurality of storage plates fixedly installed inside the ultra-low temperature refrigerator, a plurality of sample cells fixedly arranged between every two of the storage plates, a sensor fixedly arranged on the surface of the storage plate, the sensor electrically connected to a controller, and the controller electrically connected to the ultra-low temperature refrigerator.
[0010] Preferably, the plurality of sample cells are arranged equidistantly.
[0011] Preferably, the temperature inside the ultra-low temperature refrigerator detected by the sensor is Ta, the set temperature inside the ultra-low temperature refrigerator is Ts, and the controller determines the value of Ta. When the value of Ta is greater than Ts, the controller sends an instruction to the ultra-low temperature refrigerator, and the ultra-low temperature refrigerator controls the compressor to start refrigeration. When the value of Ta is less than or equal to Ts, the controller sends an instruction to the ultra-low temperature refrigerator, and the ultra-low temperature refrigerator controls the compressor to shut down.
[0012] Compared with the related art, the intelligent early warning system for facilitating sample preservation provided by the present invention has the following beneficial effects:
[0013] The present invention provides an intelligent early warning system for facilitating sample preservation. During the normal operation of an ultra-low temperature refrigerator, a sensor monitors the temperature inside the ultra-low temperature refrigerator in real time, and the sensor transmits the monitored temperature to a controller, and the controller sends instructions to control the start and stop of a compressor of the ultra-low temperature refrigerator, thereby ensuring that the temperature inside the ultra-low temperature refrigerator remains constant, so as to facilitate the proper preservation of samples placed in sample cells; the controller analyzes daily operation data of the ultra-low temperature refrigerator to establish a data model, and when it is detected that the data inside the ultra-low temperature refrigerator deviates from the data model value, even if the temperature inside the ultra-low temperature refrigerator has not exceeded a set range, an early warning can be issued in advance, so as to facilitate the preservation of samples, which can not only reduce costs and reduce the use of sensors, but also remind maintenance personnel before an accident occurs, so as to better protect the safety of samples. BRIEF DESCRIPTION OF THE DRAWINGS
[0014] Figure 1 It is a schematic diagram of the overall structure of the present invention;
[0015] Figure 2 It is a schematic diagram of the sample cell structure of the present invention;
[0016] Figure 3 It is a system flow chart of the present invention.
[0017] In the figure: 1. ultra-low temperature refrigerator, 11. door, 12. storage plate, 13. sensor, 14. sample cell. DETAILED DESCRIPTION
[0018] See also Figure 1-Figure 3 The present invention provides a technical solution, including an ultra-low temperature refrigerator 1, the ultra-low temperature refrigerator 1 includes a compressor and a door 11, a plurality of storage plates 12 are fixedly installed inside the ultra-low temperature refrigerator 1, a plurality of sample cells 14 are fixedly arranged between every two storage plates 12, a sensor 13 is fixedly arranged on the surface of the storage plate 12, the sensor 13 is electrically connected to a controller, and the controller is electrically connected to the ultra-low temperature refrigerator 1;
[0019] During the normal operation of the ultra-low temperature refrigerator 1, the sensor 13 monitors the temperature inside the ultra-low temperature refrigerator 1 in real time, and the sensor 13 transmits the monitored temperature to the controller, and the controller sends instructions to control the start and stop of the compressor of the ultra-low temperature refrigerator 1, thereby ensuring that the temperature inside the ultra-low temperature refrigerator 1 remains constant, so as to facilitate the proper preservation of the samples placed in the sample cells 14.
[0020] A plurality of sample cells 14 are arranged at equal intervals;
[0021] The temperature inside the ultra-low temperature refrigerator 1 detected by the sensor 13 is Ta, and the set temperature inside the ultra-low temperature refrigerator 1 is Ts. The controller determines the value of Ta. When the value of Ta is greater than Ts, the controller sends an instruction to the ultra-low temperature refrigerator 1, and the ultra-low temperature refrigerator 1 controls the compressor to start refrigeration. When the value of Ta is less than or equal to Ts, the controller sends an instruction to the ultra-low temperature refrigerator 1, and the ultra-low temperature refrigerator 1 controls the compressor to shut down.
[0022] The controller analyzes the daily operating data of the ultra-low temperature refrigerator 1 to establish a data model. When it is detected that the data inside the ultra-low temperature refrigerator 1 deviates from the data model value, even if the internal temperature of the ultra-low temperature refrigerator 1 has not exceeded the set range, an early warning can be issued to facilitate the preservation of samples. This can not only reduce costs and reduce the use of sensors 13, but also remind maintenance personnel before an accident occurs, thereby better protecting the safety of samples.
Claims
1. An intelligent early warning system for facilitating sample preservation, comprising an ultra-low temperature refrigerator (1), wherein the ultra-low temperature refrigerator (1) comprises a compressor and a door (11), Features: A plurality of storage plates (12) are fixedly installed inside the ultra-low temperature refrigerator (1), a plurality of sample cells (14) are fixedly arranged between every two of the storage plates (12), a sensor (13) is fixedly arranged on the surface of the storage plates (12), the sensor (13) is electrically connected to a controller, and the controller is electrically connected to the ultra-low temperature refrigerator (1).
2. An intelligent early warning system for facilitating sample preservation according to claim 1, Features: A plurality of the sample cells (14) are arranged at equal intervals.
3. An intelligent early warning system for facilitating sample preservation according to claim 2, Features: The temperature inside the ultra-low temperature refrigerator (1) detected by the sensor (13) is Ta, and the set temperature inside the ultra-low temperature refrigerator (1) is Ts. The controller determines the value of Ta. When the value of Ta is greater than Ts, the controller sends an instruction to the ultra-low temperature refrigerator (1), and the ultra-low temperature refrigerator (1) controls the compressor to start refrigeration. When the value of Ta is less than or equal to Ts, the controller sends an instruction to the ultra-low temperature refrigerator (1), and the ultra-low temperature refrigerator (1) controls the compressor to stop.
