Temperature control method and system for low-temperature experimental probe
By introducing a voltage stabilization unit and intelligent control module into the low-temperature experimental probe temperature control system, the operating power of the pre-cooling unit is dynamically adjusted, and the problems of unstable temperature control and low control accuracy in traditional systems are solved, and more accurate temperatures are achieved Control and more efficient resource utilization improve the application effect of low-temperature probes.
Patent Information
- Application Number
- CN202411275419.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-12
- Publication Date
- 2024-12-06
AI Technical Summary
The traditional gas throttling refrigeration system has low control accuracy and lacks feedback adjustment mechanism in the temperature control of low temperature probes, which leads to unstable temperature control and cannot be dynamically adjusted according to real-time demand and environmental changes. The gas cylinder pressure drops, resulting in insufficient gas supply. It affects the accuracy and reliability of experimental results.
A low-temperature experimental probe temperature control system including argon cylinder, pressure stabilization unit, pre-cooling unit and control module is designed. Through the acquisition unit, judgment unit, processing unit and adjustment unit in the control module, it works in a coordinated manner according to real-time requirements. Dynamically adjust the operating power of the pre-cooling unit and environmental conditions to ensure that the low-temperature probe obtains a stable pressure argon supply and realizes intelligent temperature control.
Improve the stability and accuracy of the cooling effect, reduce temperature fluctuations, avoid insufficient gas supply due to the drop in the pressure of the cylinder, achieve more accurate temperature control, and improve the application of low-temperature experimental probes in high-precision medicine Effect.
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Figure CN119088122A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the field of intelligent control technology, and in particular to a temperature control method and system for a low-temperature experimental probe. Background Art
[0002] With the advancement of technology, cryogenics are increasingly used in medicine. Cryogenics can be used to kill diseased tissue cells to treat tumors and other diseases. Since the temperature of gas throttling refrigeration is easy to control and the diameter of the cryogenic probe can be made very small, it is very suitable for the treatment of solid tumors.
[0003] However, traditional gas throttling refrigeration control systems usually rely on manual operation or preset programs, and cannot make dynamic adjustments based on real-time experimental needs and environmental changes. This results in unstable cooling effects and makes it difficult to meet the strict temperature requirements required for high-precision experiments. Traditional systems lack an intelligent feedback mechanism and cannot adjust power based on the actual temperature of the cryogenic probe monitored in real time. In addition, traditional gas throttling refrigeration systems use gas cylinders to directly supply gas, and the gas supply is directly adjusted by adjusting the valve opening. Since the pressure in the gas cylinder is fixed, there is a high pressure at the beginning and sufficient gas supply. As the use time increases, the gas cylinder pressure decreases, resulting in a reduction in gas supply, which can easily lead to excessive temperature fluctuations during the experiment and cannot be accurately controlled within the required temperature range, thereby affecting the accuracy and reliability of the experimental results.
[0004] Therefore, it is necessary to design a temperature control method and system for a low-temperature experimental probe to solve the problems existing in the current technology. Summary of the invention
[0005] In view of this, the present invention proposes a temperature control method and system for a cryogenic experimental probe, aiming to solve the problems of low control accuracy, lack of feedback adjustment mechanism and unstable temperature control in the current gas throttling refrigeration type cryogenic probe.
[0006] In one aspect, the present invention provides a temperature control system for a low temperature experimental probe, comprising:
[0007] An argon gas cylinder, a voltage stabilizing unit, a precooling unit, a cryogenic probe and a control module, wherein the argon gas cylinder is used to provide argon gas to the voltage stabilizing unit, one end of the voltage stabilizing unit is connected to the argon gas cylinder, and the other end is connected to the precooling unit, the voltage stabilizing unit is used to provide argon gas with stable pressure to the precooling unit, the precooling unit is communicated with the high-pressure air inlet of the cryogenic probe, the control module is connected to the voltage stabilizing unit, the precooling unit and the cryogenic probe, and the control module includes a collection unit, a judgment unit, a processing unit, an adjustment unit and a storage unit;
[0008] The collection unit is configured to collect usage requirements of the low-temperature probe, the usage requirements including a minimum required temperature and a minimum required time, and determine whether to start the precooling unit according to the usage requirements;
[0009] When the acquisition unit determines to turn on the pre-cooling unit, the processing unit is configured to acquire the use environment of the low-temperature probe, combine the use environment with the use demand, establish an operation data set, compare the operation data set with the historical operation data set, and determine the operation power of the pre-cooling unit; when there is no data in the historical operation data set whose similarity with the operation data set is greater than a similarity threshold, determine a condition factor according to the use demand and the use environment, and determine the initial operation power of the pre-cooling unit according to the condition factor;
[0010] The judgment unit is configured to collect the actual temperature of the low-temperature probe, compare the actual temperature with the minimum required temperature, and judge whether to adjust the initial operating power according to the comparison result after the processing unit determines the initial operating power and controls the precooling unit to operate;
[0011] The adjustment unit is configured to adjust the initial operating power by determining an adjustment coefficient according to an actual temperature when the judgment unit determines to adjust the initial operating power, use the adjusted operating power as the operating power of the precooling unit, and store the usage requirements, usage environment and operating power in the storage unit.
[0012] Furthermore, when the acquisition unit determines whether to turn on the precooling unit according to the usage demand, it includes:
[0013] When the minimum required temperature is less than a temperature threshold or the minimum required time is greater than a time threshold, the acquisition unit determines to start the precooling unit;
[0014] When the minimum required temperature is greater than or equal to a temperature threshold and the minimum required time is less than or equal to a time threshold, the acquisition unit determines not to start the precooling unit.
[0015] Furthermore, when the processing unit compares the operating data set with the historical operating data set to determine the operating power of the precooling unit, it includes:
[0016] The processing unit calculates the similarity between the operating data set and each set of data in the historical operating data set, and the similarity is calculated by the following formula:
[0017]
[0018] Among them, Sj represents the similarity between the running data set and the j-th group of data in the historical running data set, n represents the total number of parameters in the running data set, wi represents the weight coefficient of the i-th parameter, xi represents the i-th parameter value in the running data set, and yji represents the i-th parameter value in the j-th group of data in the historical running data set. i represents the standard deviation of the i-th parameter value;
[0019] The processing unit determines the operating power of the pre-cooling unit according to the similarity.
[0020] Further, when the processing unit determines the operating power of the precooling unit according to the similarity, it includes:
[0021] When there is data in the historical operation data set whose similarity with the operation data set is greater than a similarity threshold, determining the operation power of the precooling unit according to the historical operation data set;
[0022] When there is no data in the historical operation data set whose similarity with the operation data set is greater than a similarity threshold, a condition factor is determined according to the usage requirement and the usage environment, and the initial operation power of the precooling unit is determined according to the condition factor.
[0023] Further, when the processing unit determines the operating power of the precooling unit according to the historical operating data set, it includes:
[0024] When the data in the historical operation data set whose similarity with the operation data set is greater than the similarity threshold is unique, the processing unit determines the historical operation power in the historical operation data set as the current operation power of the precooling unit;
[0025] When the data in the historical operation data set whose similarity with the operation data set is greater than a similarity threshold is not unique, the processing unit determines the operation power of the precooling unit based on multivariate weighted fusion.
[0026] Furthermore, when the processing unit determines the operating power of the precooling unit based on multivariate weighted fusion, it includes:
[0027] The processing unit selects data in the historical operation data set whose similarity with the operation data set is greater than a similarity threshold, establishes a similarity set, and calculates a weight corresponding to each historical operation power in the similarity set;
[0028]
[0029] Wherein, Qt represents the weight corresponding to the t-th historical operating power in the similarity set, St represents the similarity corresponding to the t-th historical operating power in the similarity set, Se represents the weight corresponding to the e-th historical operating power in the similarity set, and m represents the number of historical operating powers in the similarity set;
[0030] The processing unit determines the operating power of the precooling unit according to the weight corresponding to each historical operating power in the similarity set and each historical operating power;
[0031]
[0032] Among them, P represents the operating power of the precooling unit, Qt represents the weight corresponding to the t-th historical operating power in the similarity set, Pt represents the similarity corresponding to the t-th historical operating power in the similarity set, and m represents the number of historical operating powers in the similarity set.
[0033] Further, when the processing unit determines the condition factor according to the use demand and the use environment and determines the initial operating power of the precooling unit according to the condition factor, it includes:
[0034]
[0035] Wherein, T represents the minimum required temperature, tmin represents the minimum required time, E represents the use environment, k represents a non-zero number, and C represents the condition factor;
[0036] The processing unit obtains a condition factor difference according to the condition factor and the standard factor, wherein the condition factor difference is the difference between the condition factor and the standard factor, and determines the initial operating power according to the condition factor difference, wherein the initial operating power is proportional to the condition factor difference.
[0037] Further, when the judging unit judges whether to adjust the initial operating power according to the comparison result, it includes:
[0038] When the actual temperature is less than or equal to the minimum required temperature, the judgment unit determines not to adjust the initial operating power, and uses the initial operating power as the operating power of the precooling unit;
[0039] When the actual temperature is greater than the minimum required temperature, the determination unit determines to adjust the initial operating power.
[0040] Furthermore, when the adjustment unit determines the adjustment coefficient according to the actual temperature to adjust the initial operating power, it includes:
[0041] The adjustment unit obtains a temperature difference value according to the actual temperature and the minimum required temperature, the temperature difference value is the difference between the actual temperature and the minimum required temperature, compares the temperature difference value with a first preset temperature difference value and a second preset temperature difference value respectively, determines an adjustment coefficient according to the comparison result to adjust the initial operating power, and the first preset temperature difference value is less than the second preset temperature difference value;
[0042] When the temperature difference is less than or equal to the first preset temperature difference, the first adjustment coefficient is determined to adjust the initial operating power to obtain the adjusted operating power; when the temperature difference is greater than the first preset temperature difference and less than or equal to the second preset temperature difference, the second adjustment coefficient is determined to adjust the initial operating power to obtain the adjusted operating power, and when the temperature difference is greater than the second preset temperature difference, the third adjustment coefficient is determined to adjust the initial operating power to obtain the adjusted operating power; the first adjustment coefficient is less than the second adjustment coefficient, and the second adjustment coefficient is less than the third adjustment coefficient.
[0043] Compared with the prior art, the beneficial effects of the present invention are as follows: the voltage stabilizing unit and the pre-cooling unit ensure that the cryogenic probe obtains a stable pressure supply of argon gas, thereby avoiding insufficient gas supply and temperature fluctuations caused by a drop in the pressure of the gas cylinder. The acquisition unit, the judgment unit, the processing unit and the adjustment unit in the control module work together to dynamically adjust the operating power of the pre-cooling unit according to real-time usage requirements and environmental conditions. The intelligent control mechanism enables the system to more accurately control the temperature of the cryogenic probe, reduce temperature fluctuations, and improve the stability and accuracy of the cooling effect. By analyzing and comparing historical operating data sets, the existing empirical data is effectively utilized to further optimize the control process of the refrigeration power. The problems of temperature instability and low control accuracy in traditional systems are solved, efficient resource utilization is achieved, and the application effect of cryogenic experimental probes in high-precision medicine is improved.
[0044] On the other hand, the present application also provides a temperature control method for a low temperature experiment probe, which is used to apply the temperature control system for the low temperature experiment probe, comprising:
[0045] Collecting the usage requirements of the low-temperature probe, the usage requirements including the minimum required temperature and the minimum required time, and determining whether to start the precooling unit according to the usage requirements;
[0046] When it is determined to turn on the precooling unit, the use environment of the low-temperature probe is collected, the use environment is combined with the use demand, an operation data set is established, the operation data set is compared with the historical operation data set, and the operation power of the precooling unit is determined; when there is no data in the historical operation data set whose similarity with the operation data set is greater than a similarity threshold, a condition factor is determined according to the use demand and the use environment, and the initial operation power of the precooling unit is determined according to the condition factor;
[0047] After determining the initial operating power and controlling the precooling unit to operate, collecting the actual temperature of the low-temperature probe, comparing the actual temperature with the minimum required temperature, and judging whether to adjust the initial operating power according to the comparison result;
[0048] When it is determined that the initial operating power is to be adjusted, the adjustment coefficient is determined according to the actual temperature to adjust the initial operating power, the adjusted operating power is used as the operating power of the precooling unit, and the usage requirements, usage environment and operating power are stored in a storage unit.
[0049] It is understandable that the above-mentioned temperature control method and system for low-temperature experimental probes have the same beneficial effects, which will not be described in detail here. BRIEF DESCRIPTION OF THE DRAWINGS
[0050] Various other advantages and benefits will become apparent to those of ordinary skill in the art by reading the detailed description of the preferred embodiments below. The accompanying drawings are only for the purpose of illustrating the preferred embodiments and are not to be considered as limiting the present invention. Moreover, the same reference symbols are used throughout the accompanying drawings to represent the same components. In the accompanying drawings:
[0051] Figure 1 A structural block diagram of a temperature control system for a low-temperature experimental probe provided in an embodiment of the present invention;
[0052] Figure 2 The present invention provides a flow chart of a temperature control method for a cryogenic experimental probe according to an embodiment of the present invention. DETAILED DESCRIPTION
[0053] Exemplary embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings. Although exemplary embodiments of the present disclosure are shown in the accompanying drawings, it should be understood that the present disclosure can be implemented in various forms and should not be limited by the embodiments described herein. On the contrary, these embodiments are provided in order to enable a more thorough understanding of the present disclosure and to fully convey the scope of the present disclosure to those skilled in the art. It should be noted that, in the absence of conflict, the embodiments of the present invention and the features described in the embodiments can be combined with each other. The present invention will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.
[0054] With the continuous development of cryogenic technology, cryogenics are increasingly used in the medical field. For example, killing diseased tissue cells by low temperature has become an effective means of treating tumors and other diseases. As an efficient refrigeration tool, cryogenic probes are particularly suitable for cryotherapy of solid tumors due to their small diameter and precise temperature control. However, the existing gas throttling refrigeration system still has many shortcomings.
[0055] Traditional gas throttling refrigeration control systems often rely on fixed procedures or manual operations, which cannot cope with real-time demand changes during the experiment. For example, slight fluctuations in experimental conditions may cause unstable temperature control, which in turn affects the experimental results. Due to the lack of an intelligent feedback mechanism, these systems cannot automatically adjust the refrigeration power according to the real-time changes in the actual temperature of the cryogenic probe, making it difficult to ensure that the probe temperature is always maintained within the required precise range. In addition, traditional systems usually use gas cylinders to directly supply gas and rely on manual adjustment of valves to control the gas flow. However, as the pressure in the gas cylinder gradually decreases, the gas supply gradually decreases, making it difficult to maintain a constant refrigeration effect, which can easily cause excessive temperature fluctuations during the experiment, further affecting the accuracy and reliability of the experimental results. Therefore, it is necessary to design a temperature control method and system for cryogenic experimental probes to solve the problems existing in current technology.
[0056] In some embodiments of the present application, see Figure 1 As shown, a temperature control system for a cryogenic experimental probe comprises: an argon gas cylinder, a voltage stabilizing unit, a precooling unit, a cryogenic probe and a control module. The argon gas cylinder is used to provide argon gas to the voltage stabilizing unit, one end of the voltage stabilizing unit is connected to the argon gas cylinder, and the other end is connected to the precooling unit. The voltage stabilizing unit is used to provide argon gas with stable pressure to the precooling unit. The precooling unit is connected to the high-pressure air inlet of the cryogenic probe. The control module is connected to the voltage stabilizing unit, the precooling unit and the cryogenic probe, and the control module comprises a collection unit, a judgment unit, a processing unit, an adjustment unit and a storage unit.
[0057] The collection unit is configured to collect the use requirements of the low-temperature probe, the use requirements include the minimum required temperature and the minimum required time, and determine whether to start the pre-cooling unit according to the use requirements.
[0058] When the acquisition unit determines to turn on the pre-cooling unit, the processing unit is configured to collect the use environment of the low-temperature probe, combine the use environment with the use demand, establish an operation data set, compare the operation data set with the historical operation data set, and determine the operation power of the pre-cooling unit. When there is no data in the historical operation data set whose similarity with the operation data set is greater than the similarity threshold, a condition factor is determined according to the use demand and the use environment, and the initial operation power of the pre-cooling unit is determined according to the condition factor.
[0059] The judgment unit is configured to collect the actual temperature of the low-temperature probe, compare the actual temperature with the minimum required temperature, and determine whether to adjust the initial operating power based on the comparison result after the processing unit determines the initial operating power and controls the operation of the pre-cooling unit.
[0060] The adjustment unit is configured to adjust the initial operating power by determining an adjustment coefficient according to the actual temperature when the judgment unit determines to adjust the initial operating power, use the adjusted operating power as the operating power of the precooling unit, and store the usage requirements, usage environment and operating power in the storage unit.
[0061] Specifically, the argon cylinder is used to store and provide argon. The pressure stabilizing unit is connected between the argon cylinder and the precooling unit, and is responsible for stabilizing the pressure of the argon from the argon cylinder to ensure that the argon delivered to the precooling unit has a stable pressure. The precooling unit is connected to the high-pressure air inlet of the cryogenic probe, and is used to further cool the argon after the pressure stabilization, and then deliver it to the cryogenic probe, which determines the refrigeration effect of the cryogenic probe. The cryogenic probe: directly contacts the experimental object, performs cryotherapy or experimental operations, and its temperature is controlled by the precooling unit. The control module is connected to each unit of the system and is responsible for the intelligent operation and feedback control of the entire system. The acquisition unit in the control module collects the use requirements of the cryogenic probe, including the minimum required temperature and the minimum required time, and determines whether the precooling unit needs to be started based on these requirements. The judgment unit collects the actual temperature of the cryogenic probe, compares it with the minimum required temperature, and determines whether the operating power of the precooling unit needs to be adjusted. After the processing unit determines to turn on the precooling unit, the processing unit collects the use environment information and combines the use environment with the use requirements to form an operating data set. Then the operating data set is compared with the historical operating data set to determine the operating power of the precooling unit. If there are no records in the historical data whose similarity exceeds the threshold, the processing unit will calculate the condition factor based on the current usage requirements and environmental conditions, and determine the initial operating power accordingly. When the judgment unit believes that the power needs to be adjusted, the adjustment unit will determine an adjustment coefficient based on the actual temperature to correct the initial operating power. The corrected power is used to adjust the operating status of the precooling unit and store related data for future use. The storage unit saves all data collected and processed during the operation, including usage requirements, environmental conditions, operating power, etc., to provide a reference for subsequent operations.
[0062] It can be understood that, compared with the traditional gas throttling refrigeration system, the temperature control system provided by this embodiment can dynamically adjust the refrigeration power according to the real-time use demand and environmental changes, thereby improving the stability of the cooling effect and the accuracy of temperature control. The intelligent feedback mechanism enables the system to adjust the power in real time during the application process, ensuring that the cryogenic probe is always maintained within the most suitable temperature range, reducing the need for manual intervention and avoiding temperature fluctuations caused by changes in gas cylinder pressure. In addition, the historical data stored in the storage unit provides a reference for future operations, improving the intelligence and adaptability of the system.
[0063] In some embodiments of the present application, when the collection unit determines whether to turn on the pre-cooling unit according to the use demand, it includes: when the minimum demand temperature is less than the temperature threshold or the minimum demand time is greater than the time threshold, the collection unit determines to turn on the pre-cooling unit. When the minimum demand temperature is greater than or equal to the temperature threshold and the minimum demand time is less than or equal to the time threshold, the collection unit determines not to turn on the pre-cooling unit.
[0064] Specifically, the minimum required temperature is the minimum temperature that the cryogenic probe needs to reach during the application process. If the minimum required temperature is less than the temperature threshold preset in the system, it means that the temperature required for the application is low, and the pre-cooling unit needs to be turned on to reach the required temperature. The minimum required time is the length of time that the minimum required temperature needs to be maintained during the experiment. If the minimum required time is greater than the time threshold preset in the system, it means that the experiment has a high requirement for the duration of the low temperature state, and the pre-cooling unit also needs to be turned on to ensure that the temperature is maintained for a long enough time.
[0065] It is understandable that the judgment mechanism can more accurately decide whether to turn on the pre-cooling unit when facing different experimental requirements. The threshold-based judgment method simplifies the decision-making process, improves the operating efficiency of the system, avoids unnecessary pre-cooling operations, and thus saves energy. It is conducive to reducing the possibility of human judgment errors.
[0066] In some embodiments of the present application, when the processing unit compares the operating data set with the historical operating data set to determine the operating power of the precooling unit, the processing unit calculates the similarity between the operating data set and each set of data in the historical operating data set, and the similarity is calculated by the following formula:
[0067]
[0068] Among them, Sj represents the similarity between the running data set and the j-th group of data in the historical running data set, n represents the total number of parameters in the running data set, wi represents the weight coefficient of the i-th parameter, xi represents the i-th parameter value in the running data set, and yji represents the i-th parameter value in the j-th group of data in the historical running data set. i represents the standard deviation of the i-th parameter value.
[0069] The processing unit determines the operating power of the pre-cooling unit according to the similarity.
[0070] In some embodiments of the present application, when the processing unit determines the operating power of the pre-cooling unit according to the similarity, it includes: when there is data in the historical operating data set whose similarity with the operating data set is greater than the similarity threshold, the operating power of the pre-cooling unit is determined according to the historical operating data set. When there is no data in the historical operating data set whose similarity with the operating data set is greater than the similarity threshold, a condition factor is determined according to the use demand and the use environment, and the initial operating power of the pre-cooling unit is determined according to the condition factor.
[0071] Specifically, the processing unit determines the operating power of the pre-cooling unit based on the calculation result of the similarity. If there is data in the historical operating data set whose similarity with the current operating data set is greater than the set threshold, these historical data are directly used to determine the operating power of the pre-cooling unit. If there is no data with high similarity, the condition factor is calculated according to the use requirements and the use environment, and the initial operating power of the pre-cooling unit is determined accordingly. The similarity threshold can be adjusted according to the actual application requirements, preferably 0.85-0.95.
[0072] It can be understood that by using similarity, the system can intelligently find the most matching operating parameters from historical data, thereby accurately controlling the power output of the pre-cooling unit. This improves the flexibility of the system in responding to environmental changes and ensures the temperature stability of the cryogenic probe under various complex experimental conditions. The mechanism of determining the initial operating power through conditional factors ensures that the system can still work effectively when there is no matching historical data, further enhancing the adaptability and reliability of the system.
[0073] In some embodiments of the present application, when the processing unit determines the operating power of the precooling unit according to the historical operating data set, it includes: when the data in the historical operating data set whose similarity with the operating data set is greater than the similarity threshold is unique, the processing unit determines the historical operating power in the historical operating data set as the operating power of the current precooling unit. When the data in the historical operating data set whose similarity with the operating data set is greater than the similarity threshold is not unique, the processing unit determines the operating power of the precooling unit based on multivariate weighted fusion.
[0074] In some embodiments of the present application, when the processing unit determines the operating power of the pre-cooling unit based on multivariate weighted fusion, it includes: the processing unit filters out data in the historical operating data set whose similarity with the operating data set is greater than a similarity threshold, establishes a similarity set, and calculates the weight corresponding to each historical operating power in the similarity set.
[0075]
[0076] Among them, Qt represents the weight corresponding to the t-th historical operating power in the similarity set, St represents the similarity corresponding to the t-th historical operating power in the similarity set, Se represents the weight corresponding to the e-th historical operating power in the similarity set, and m represents the number of historical operating powers in the similarity set.
[0077] The processing unit determines the operating power of the precooling unit according to the weight corresponding to each historical operating power in the similarity set and each historical operating power.
[0078]
[0079] Among them, P represents the operating power of the precooling unit, Qt represents the weight corresponding to the t-th historical operating power in the similarity set, Pt represents the similarity corresponding to the t-th historical operating power in the similarity set, and m represents the number of historical operating powers in the similarity set.
[0080] It can be understood that the multivariate weighted fusion method solves the problem of how to accurately determine the operating power of the precooling unit when there are multiple similar historical data. Compared with the method of directly selecting a single historical data, the multivariate weighted fusion takes into account the contribution of multiple similar data, making the determined operating power more accurate and reliable, and avoiding the problem of inaccurate operating power setting caused by individual data deviations. It improves the temperature control accuracy of the system in complex environments and enhances the stability and robustness of the system.
[0081] In some embodiments of the present application, when the processing unit determines the condition factor according to the use demand and the use environment and determines the initial operating power of the precooling unit according to the condition factor, it includes:
[0082]
[0083] Among them, T represents the minimum required temperature, tmin represents the minimum required time, E represents the use environment, k represents a non-zero number, and C represents the condition factor.
[0084] The processing unit obtains a condition factor difference according to the condition factor and the standard factor, the condition factor difference is the difference between the condition factor and the standard factor, and determines the initial operating power according to the condition factor difference, and the initial operating power is proportional to the condition factor difference.
[0085] Specifically, the use environment includes the ambient temperature or the ambient humidity. The condition factor reflects the operation requirements of the precooling unit under the current experimental environment and requirements. The k value is used to exclude the case where the denominator in the calculation formula is zero. The standard factor is a preset reference value, which is obtained by taking the temperature that the system can continuously and stably reach as the minimum required temperature, taking 25 degrees Celsius as the use environment, and taking the shortest time the system lasts at the minimum required temperature as the minimum required time.
[0086] It can be understood that by introducing the comparison between the condition factor and the standard factor, a mechanism is provided to dynamically determine the initial operating power of the pre-cooling unit. Compared with the traditional fixed initial power setting method, this scheme can more accurately respond to the cooling needs under different experimental conditions. Through the proportional adjustment method of the condition factor difference, it can flexibly adapt to various experimental environments and demand changes, thereby improving the accuracy and reliability of temperature control and ensuring the accuracy and consistency of application results. This design is particularly suitable for experimental scenarios that require high-precision temperature control, so that the system can maintain optimal performance under different conditions.
[0087] In some embodiments of the present application, when the judging unit judges whether to adjust the initial operating power according to the comparison result, it includes:
[0088] When the actual temperature is less than or equal to the minimum required temperature, the determination unit determines not to adjust the initial operating power, and uses the initial operating power as the operating power of the precooling unit.
[0089] When the actual temperature is greater than the minimum required temperature, the determination unit determines to adjust the initial operating power.
[0090] In some embodiments of the present application, when the adjustment unit determines the adjustment coefficient according to the actual temperature to adjust the initial operating power, it includes:
[0091] The adjustment unit obtains a temperature difference based on the actual temperature and the minimum required temperature, where the temperature difference is the difference between the actual temperature and the minimum required temperature. The temperature difference is compared with a first preset temperature difference and a second preset temperature difference, respectively. An adjustment coefficient is determined based on the comparison result to adjust the initial operating power, where the first preset temperature difference is smaller than the second preset temperature difference.
[0092] When the temperature difference is less than or equal to the first preset temperature difference, the first adjustment coefficient is determined to adjust the initial operating power to obtain the adjusted operating power. When the temperature difference is greater than the first preset temperature difference and less than or equal to the second preset temperature difference, the second adjustment coefficient is determined to adjust the initial operating power to obtain the adjusted operating power, and when the temperature difference is greater than the second preset temperature difference, the third adjustment coefficient is determined to adjust the initial operating power to obtain the adjusted operating power. The first adjustment coefficient is less than the second adjustment coefficient, and the second adjustment coefficient is less than the third adjustment coefficient.
[0093] It is understandable that the hierarchical adjustment coefficient design enables the system to flexibly respond to different degrees of temperature deviation. By selecting different adjustment coefficients according to the size of the temperature difference, it is possible to quickly respond to temperature changes without over-consuming resources and effectively controlling the temperature. The hierarchical adjustment mechanism ensures that the system can maintain a stable temperature control effect when facing different experimental requirements, improves the flexibility and adaptability of the system, and also improves the accuracy and reliability of the experimental results.
[0094] In the above embodiment, the voltage stabilizing unit and the precooling unit ensure that the cryogenic probe obtains a stable pressure supply of argon gas, thereby avoiding insufficient gas supply and temperature fluctuations caused by a drop in the pressure of the gas cylinder. Through the collaborative work of the acquisition unit, the judgment unit, the processing unit and the adjustment unit in the control module, the operating power of the precooling unit can be dynamically adjusted according to real-time usage requirements and environmental conditions. The intelligent control mechanism enables the system to more accurately control the temperature of the cryogenic probe, reduce temperature fluctuations, and improve the stability and accuracy of the cooling effect. By analyzing and comparing historical operating data sets, the existing empirical data is effectively utilized to further optimize the control process of the refrigeration power. It solves the problems of temperature instability and low control accuracy in traditional systems, realizes efficient utilization of resources, and improves the application effect of cryogenic experimental probes in high-precision medicine.
[0095] In another preferred embodiment based on the above embodiment, refer to Figure 2 As shown, this embodiment provides a temperature control method for a low temperature experiment probe, which is used to apply the temperature control system for the low temperature experiment probe, including:
[0096] S100: collecting usage requirements of the low-temperature probe, the usage requirements including the minimum required temperature and the minimum required time, and determining whether to start the precooling unit according to the usage requirements;
[0097] S200: when it is determined that the pre-cooling unit is turned on, the use environment of the low-temperature probe is collected, the use environment is combined with the use demand, an operation data set is established, the operation data set is compared with the historical operation data set, and the operation power of the pre-cooling unit is determined; when there is no data in the historical operation data set whose similarity with the operation data set is greater than the similarity threshold, a condition factor is determined according to the use demand and the use environment, and the initial operation power of the pre-cooling unit is determined according to the condition factor;
[0098] S300: After the initial operating power is determined and the pre-cooling unit is controlled to operate, the actual temperature of the low-temperature probe is collected, the actual temperature is compared with the minimum required temperature, and whether the initial operating power is adjusted is determined according to the comparison result;
[0099] S400: When it is determined that the initial operating power is to be adjusted, the adjustment coefficient is determined according to the actual temperature to adjust the initial operating power, the adjusted operating power is used as the operating power of the precooling unit, and the usage requirements, usage environment and operating power are stored in the storage unit.
[0100] It is understandable that the voltage stabilizing unit and the precooling unit ensure that the cryogenic probe obtains a stable pressure supply of argon gas, avoiding insufficient gas supply and temperature fluctuations caused by the drop in gas cylinder pressure. Through the collaborative work of the acquisition unit, judgment unit, processing unit and adjustment unit in the control module, the operating power of the precooling unit can be dynamically adjusted according to real-time usage requirements and environmental conditions. The intelligent control mechanism enables the system to more accurately control the temperature of the cryogenic probe, reduce temperature fluctuations, and improve the stability and accuracy of the cooling effect. By analyzing and comparing historical operating data sets, the existing empirical data is effectively utilized to further optimize the control process of the refrigeration power. It solves the problems of temperature instability and low control accuracy in traditional systems, realizes efficient utilization of resources, and improves the application effect of cryogenic experimental probes in high-precision medicine.
[0101] Those skilled in the art will appreciate that the embodiments of the present application may be provided as methods, systems or computer program products. Therefore, the present application may take the form of a complete hardware embodiment, a complete software embodiment, or an embodiment combining software and hardware. Moreover, the present application may take the form of a computer program product implemented on one or more computer-usable storage media (including but not limited to disk storage, CD-ROM, optical storage, etc.) containing computer-usable program codes.
[0102] The present application is described with reference to the flowcharts and / or block diagrams of the methods, devices (systems) and computer program products according to the embodiments of the present application. It should be understood that each process and / or box in the flowchart and / or block diagram, as well as the combination of processes and / or boxes in the flowchart and / or block diagram, can be implemented by computer program instructions. These computer program instructions can be provided to a processor of a general-purpose computer, a special-purpose computer, an embedded processor or other programmable data processing device to produce a machine, so that the instructions executed by the processor of the computer or other programmable data processing device generate instructions for implementing the processes in the flowchart and / or block diagram. Figure 1 A process or multiple processes and / or boxes Figure 1 A device that provides the functions specified in a block or multiple blocks.
[0103] These computer program instructions may also be stored in a computer-readable memory capable of directing a computer or other programmable data processing device to operate in a specific manner, so that the instructions stored in the computer-readable memory produce an article of manufacture comprising an instruction device, which implements the process Figure 1 A process or multiple processes and / or boxes Figure 1 A function specified in one or more boxes.
[0104] These computer program instructions can also be loaded onto a computer or other programmable data processing device so that a series of operating steps are executed on the computer or other programmable device to produce a computer-implemented process, thereby providing instructions for implementing the process. Figure 1 A process or multiple processes and / or boxes Figure 1 The steps for the functions specified in one or more boxes.
[0105] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the above embodiments, ordinary technicians in the relevant field should understand that the specific implementation methods of the present invention can still be modified or replaced by equivalents. Any modification or equivalent replacement that does not depart from the spirit and scope of the present invention should be covered within the scope of protection of the claims of the present invention.
Claims
1. A temperature control system for a low temperature experimental probe, characterized in that: include: An argon gas cylinder, a voltage stabilizing unit, a precooling unit, a cryogenic probe and a control module, wherein the argon gas cylinder is used to provide argon gas to the voltage stabilizing unit, one end of the voltage stabilizing unit is connected to the argon gas cylinder, and the other end is connected to the precooling unit, the voltage stabilizing unit is used to provide argon gas with stable pressure to the precooling unit, the precooling unit is communicated with the high-pressure air inlet of the cryogenic probe, the control module is connected to the voltage stabilizing unit, the precooling unit and the cryogenic probe, and the control module includes a collection unit, a judgment unit, a processing unit, an adjustment unit and a storage unit; The collection unit is configured to collect usage requirements of the low-temperature probe, the usage requirements including a minimum required temperature and a minimum required time, and determine whether to start the precooling unit according to the usage requirements; When the acquisition unit determines to turn on the pre-cooling unit, the processing unit is configured to acquire the use environment of the low-temperature probe, combine the use environment with the use demand, establish an operation data set, compare the operation data set with the historical operation data set, and determine the operation power of the pre-cooling unit; when there is no data in the historical operation data set whose similarity with the operation data set is greater than a similarity threshold, determine a condition factor according to the use demand and the use environment, and determine the initial operation power of the pre-cooling unit according to the condition factor; The judgment unit is configured to collect the actual temperature of the low-temperature probe, compare the actual temperature with the minimum required temperature, and judge whether to adjust the initial operating power according to the comparison result after the processing unit determines the initial operating power and controls the precooling unit to operate; The adjustment unit is configured to adjust the initial operating power by determining an adjustment coefficient according to an actual temperature when the judgment unit determines to adjust the initial operating power, use the adjusted operating power as the operating power of the precooling unit, and store the usage requirements, usage environment and operating power in the storage unit.
2. The temperature control system for a cryogenic experiment probe according to claim 1, characterized in that: When the acquisition unit determines whether to turn on the pre-cooling unit according to the usage demand, it includes: When the minimum required temperature is less than a temperature threshold or the minimum required time is greater than a time threshold, the acquisition unit determines to start the precooling unit; When the minimum required temperature is greater than or equal to a temperature threshold and the minimum required time is less than or equal to a time threshold, the acquisition unit determines not to start the precooling unit.
3. The temperature control system for a cryogenic experiment probe according to claim 1, characterized in that: When the processing unit compares the operating data set with the historical operating data set to determine the operating power of the precooling unit, it includes: The processing unit calculates the similarity between the operating data set and each set of data in the historical operating data set, and the similarity is calculated by the following formula: ; Among them, Sj represents the similarity between the running data set and the j-th group of data in the historical running data set, n represents the total number of parameters in the running data set, wi represents the weight coefficient of the i-th parameter, xi represents the i-th parameter value in the running data set, and yji represents the i-th parameter value in the j-th group of data in the historical running data set. i represents the standard deviation of the i-th parameter value; The processing unit determines the operating power of the pre-cooling unit according to the similarity.
4. The temperature control system for a cryogenic experiment probe according to claim 3, characterized in that: When the processing unit determines the operating power of the precooling unit according to the similarity, it includes: When there is data in the historical operation data set whose similarity with the operation data set is greater than a similarity threshold, determining the operation power of the precooling unit according to the historical operation data set; When there is no data in the historical operation data set whose similarity with the operation data set is greater than a similarity threshold, a condition factor is determined according to the usage requirement and the usage environment, and the initial operation power of the precooling unit is determined according to the condition factor.
5. The temperature control system for a cryogenic experiment probe according to claim 4, characterized in that: When the processing unit determines the operating power of the precooling unit according to the historical operating data set, it includes: When the data in the historical operation data set whose similarity with the operation data set is greater than the similarity threshold is unique, the processing unit determines the historical operation power in the historical operation data set as the current operation power of the precooling unit; When the data in the historical operation data set whose similarity with the operation data set is greater than a similarity threshold is not unique, the processing unit determines the operation power of the precooling unit based on multivariate weighted fusion.
6. The temperature control system for a cryogenic experiment probe according to claim 5, characterized in that: When the processing unit determines the operating power of the precooling unit based on multivariate weighted fusion, it includes: The processing unit selects data in the historical operation data set whose similarity with the operation data set is greater than a similarity threshold, establishes a similarity set, and calculates a weight corresponding to each historical operation power in the similarity set; ; Wherein, Qt represents the weight corresponding to the t-th historical operating power in the similarity set, St represents the similarity corresponding to the t-th historical operating power in the similarity set, Se represents the weight corresponding to the e-th historical operating power in the similarity set, and m represents the number of historical operating powers in the similarity set; The processing unit determines the operating power of the precooling unit according to the weight corresponding to each historical operating power in the similarity set and each historical operating power; ; Among them, P represents the operating power of the precooling unit, Qt represents the weight corresponding to the t-th historical operating power in the similarity set, Pt represents the similarity corresponding to the t-th historical operating power in the similarity set, and m represents the number of historical operating powers in the similarity set.
7. The temperature control system for a cryogenic experiment probe according to claim 4, characterized in that: When the processing unit determines the condition factor according to the use demand and the use environment and determines the initial operating power of the precooling unit according to the condition factor, it includes: ; Wherein, T represents the minimum required temperature, tmin represents the minimum required time, E represents the use environment, k represents a non-zero number, and C represents the condition factor; The processing unit obtains a condition factor difference according to the condition factor and the standard factor, wherein the condition factor difference is the difference between the condition factor and the standard factor, and determines the initial operating power according to the condition factor difference, wherein the initial operating power is proportional to the condition factor difference.
8. The temperature control system for a cryogenic experiment probe according to claim 7, characterized in that: When the judging unit judges whether to adjust the initial operating power according to the comparison result, it includes: When the actual temperature is less than or equal to the minimum required temperature, the judgment unit determines not to adjust the initial operating power, and uses the initial operating power as the operating power of the precooling unit; When the actual temperature is greater than the minimum required temperature, the determination unit determines to adjust the initial operating power.
9. The temperature control system for a cryogenic experiment probe according to claim 8, characterized in that: When the adjustment unit determines the adjustment coefficient according to the actual temperature to adjust the initial operating power, it includes: The adjustment unit obtains a temperature difference value according to the actual temperature and the minimum required temperature, the temperature difference value is the difference between the actual temperature and the minimum required temperature, compares the temperature difference value with a first preset temperature difference value and a second preset temperature difference value respectively, determines an adjustment coefficient according to the comparison result to adjust the initial operating power, and the first preset temperature difference value is less than the second preset temperature difference value; When the temperature difference is less than or equal to the first preset temperature difference, the first adjustment coefficient is determined to adjust the initial operating power to obtain the adjusted operating power; when the temperature difference is greater than the first preset temperature difference and less than or equal to the second preset temperature difference, the second adjustment coefficient is determined to adjust the initial operating power to obtain the adjusted operating power, and when the temperature difference is greater than the second preset temperature difference, the third adjustment coefficient is determined to adjust the initial operating power to obtain the adjusted operating power; the first adjustment coefficient is less than the second adjustment coefficient, and the second adjustment coefficient is less than the third adjustment coefficient.
10. A temperature control method for a cryogenic experiment probe, applied to the temperature control system for a cryogenic experiment probe as claimed in any one of claims 1 to 9, characterized in that: include: Collecting the usage requirements of the low-temperature probe, the usage requirements including the minimum required temperature and the minimum required time, and determining whether to start the precooling unit according to the usage requirements; When it is determined to turn on the precooling unit, the use environment of the low-temperature probe is collected, the use environment is combined with the use demand, an operation data set is established, the operation data set is compared with the historical operation data set, and the operation power of the precooling unit is determined; when there is no data in the historical operation data set whose similarity with the operation data set is greater than a similarity threshold, a condition factor is determined according to the use demand and the use environment, and the initial operation power of the precooling unit is determined according to the condition factor; After determining the initial operating power and controlling the precooling unit to operate, collecting the actual temperature of the low-temperature probe, comparing the actual temperature with the minimum required temperature, and judging whether to adjust the initial operating power according to the comparison result; When it is determined that the initial operating power is to be adjusted, the adjustment coefficient is determined according to the actual temperature to adjust the initial operating power, the adjusted operating power is used as the operating power of the precooling unit, and the usage requirements, usage environment and operating power are stored in a storage unit.
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