Composite health-care product based on gamma-aminobutyric acid and preparation method of composite health-care product

Abstract

The invention belongs to the technical field of food, and particularly relates to a composite health care product based on gamma-aminobutyric acid and a preparation method of the composite health care product. The composite health-care product based on gamma-aminobutyric acid comprises the following components in percentage by weight: 10-30% of gamma-aminobutyric acid; 5-15% of a spina date seed extract; 3-10% of a lemon melissa extract; 2-8% of vitamin B; 50-70% of natural fructose; the preparation method comprises the following steps: (1) mixing the spina date seed extract, the lemon balm extract, the B vitamins, the gamma-aminobutyric acid and the natural fructose according to a formula, and uniformly stirring; (2) adding a small amount of water and ethanol while stirring, and granulating; (3) drying treatment; and (4) screening to collect particles with the particle size of 0.5-2.0 mm so as to obtain the gamma-aminobutyric acid-based composite health-care product. The gamma-aminobutyric acid-based composite health care product prepared by the method disclosed by the invention can effectively relieve mental stress, improve sleep quality and meet comprehensive requirements of a human body on various nutritional ingredients.

Description

Technical Field

[0001] The invention belongs to the technical field of food, and in particular relates to a composite health product based on gamma-aminobutyric acid and a preparation method thereof. Background Art

[0002] As a non-protein amino acid, γ-aminobutyric acid has been widely recognized as an important neurotransmitter, especially showing significant physiological activity in regulating nervous system function, improving sleep quality and lowering blood pressure. With the increase of social pressure, people's demand for health products that can relieve mental stress and improve sleep quality is growing. However, most of the existing health products on the market are based on a single ingredient, with limited effects in relieving mental stress and improving sleep quality, and cannot fully meet the comprehensive needs of the human body for multiple nutrients. Summary of the invention

[0003] In view of the above-mentioned deficiencies in the prior art, the present invention provides a composite health product based on γ-aminobutyric acid and a preparation method thereof, which can effectively solve the problems that the existing health products have limited effects in relieving mental stress and improving sleep quality and cannot fully meet the comprehensive needs of the human body for multiple nutrients.

[0004] To achieve the above object, the present invention provides the following technical solutions:

[0005] A composite health product based on gamma-aminobutyric acid comprises the following components in percentage by weight: gamma-aminobutyric acid: 10-30%; spinosa jujube seed extract: 5-15%; lemon balm extract: 3-10%; B vitamins: 2-8%; and natural fructose: 50-70%.

[0006] Furthermore, the invention comprises the following components in weight percentage: γ-aminobutyric acid: 20%; Ziziphus jujuba seed extract: 10%; Lemon balm extract: 6%; B vitamins: 5%; and natural fructose: 59%.

[0007] Furthermore, the Ziziphus jujuba seed extract and the lemon balm extract are prepared by the following method:

[0008] (1) crushing the Chinese date seeds and lemon balm to a particle size of 100-200 mesh, adding 4-6 times the weight of each Chinese medicine and 70-75% ethanol for reflux extraction, and extracting twice, each time for 1-2 hours;

[0009] (2) concentrating the combined extracts under reduced pressure until an extract having a relative density of 1.12-1.15 is obtained;

[0010] (3) adding ethanol to the extract to adjust the ethanol content to 65%-75%, leaving it to stand for 24 hours and then collecting the supernatant;

[0011] (4) concentrating the supernatant under reduced pressure until the relative density is 1.12-1.15 to obtain a concentrated solution;

[0012] (5) adding 2-3 times the weight of water to the concentrate, stirring for 3-4 hours, and then standing and refrigerating for 24 hours, taking the supernatant to obtain the Ziziphus jujuba seed extract and the lemon balm extract.

[0013] Furthermore, the B vitamins include thiamine, riboflavin, niacin, pantothenic acid, pyridoxine, biotin, folic acid, and cobalamin.

[0014] The method for preparing the composite health product based on γ-aminobutyric acid comprises the following steps:

[0015] (1) Mix the Chinese jujube seed extract, lemon balm extract, B vitamins, γ-aminobutyric acid and natural fructose according to the formula, and stir at a low speed for 15-30 minutes until a uniform powdery material is formed;

[0016] (2) adding a small amount of water and ethanol to the product obtained in step (1) under the condition that the ambient temperature does not exceed 25° C. and the relative humidity does not exceed 60%, stirring while adding, and granulating until a granular material is formed;

[0017] (3) drying the product obtained in step (2) at a temperature of 40-50° C. until the moisture content drops below 5%;

[0018] (4) The product obtained in step (3) is sieved by a sieving machine to collect particles with a particle size between 0.5 and 2.0 mm to obtain a composite health product based on γ-aminobutyric acid.

[0019] Compared with the prior art, the present invention has the following beneficial effects:

[0020] 1. In the present invention, γ-aminobutyric acid is used as a core ingredient to exert sedative and anti-anxiety effects, while improving sleep quality and lowering blood pressure. The auxiliary ingredients, Chinese jujube seed extract and lemon balm extract, provide active ingredients of traditional Chinese medicine, enhance the effect of γ-aminobutyric acid, and further enhance the nutritional value and sleep-inducing effect of the health product.

[0021] 2. The B vitamins and natural fructose in the present invention provide necessary active nutrients, enhance nerve health and energy supplementation through synergistic effects, relieve stress and improve sleep, thereby achieving the purpose of synergy. DETAILED DESCRIPTION

[0022] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0023] Example 1

[0024] A composite health product based on gamma-aminobutyric acid comprises the following components in percentage by weight: gamma-aminobutyric acid: 20%; spinosa jujube seed extract: 10%; lemon balm extract: 6%; B vitamins: 5%; and natural fructose: 59%.

[0025] Wherein, the Chinese date seed extract and lemon balm extract are prepared by the following method:

[0026] (1) crushing the Chinese date seeds and lemon balm to a particle size of 100-200 mesh, adding 5 times the weight of each Chinese medicine and 70% ethanol for reflux extraction, and extracting twice, each time for 2 hours;

[0027] (2) concentrating the combined extracts under reduced pressure until an extract having a relative density of 1.12-1.15 is obtained;

[0028] (3) adding ethanol to the extract to adjust the ethanol content to 70%, leaving it to stand for 24 hours and then collecting the supernatant;

[0029] (4) concentrating the supernatant under reduced pressure until the relative density is 1.12-1.15 to obtain a concentrated solution;

[0030] (5) Add 3 times the weight of water to the concentrate, stir for 4 hours, and then refrigerate for 24 hours, and take the supernatant to obtain the Ziziphus jujuba seed extract and the lemon balm extract.

[0031] The method for preparing the composite health product based on γ-aminobutyric acid comprises the following steps:

[0032] (1) Mixing the Chinese jujube seed extract, lemon balm extract, B vitamins, γ-aminobutyric acid, and natural fructose according to the formula, and stirring at a low speed for 25 minutes until a uniform powdery material is formed;

[0033] (2) adding a small amount of water and ethanol to the product obtained in step (1) under the condition that the ambient temperature does not exceed 25° C. and the relative humidity does not exceed 60%, stirring while adding, and granulating until a granular material is formed;

[0034] (3) drying the product obtained in step (2) at 45° C. until the moisture content drops below 5%;

[0035] (4) The product obtained in step (3) is sieved by a sieving machine to collect particles with a particle size between 0.5 and 2.0 mm to obtain a composite health product based on γ-aminobutyric acid.

[0036] Example 2

[0037] A composite health product based on gamma-aminobutyric acid comprises the following components in percentage by weight: gamma-aminobutyric acid: 15%; spinosa jujube seed extract: 12%; lemon balm extract: 8%; B vitamins: 4%; and natural fructose: 61%.

[0038] Wherein, the Chinese date seed extract and lemon balm extract are prepared by the following method:

[0039] (1) crushing the Chinese date seeds and lemon balm to a particle size of 100-200 mesh, adding 4 times the weight of each Chinese medicine and 75% ethanol for reflux extraction, and extracting twice, each time for 2 hours;

[0040] (2) concentrating the combined extracts under reduced pressure until an extract having a relative density of 1.12-1.15 is obtained;

[0041] (3) adding ethanol to the extract to adjust the ethanol content to 70%, leaving it to stand for 24 hours and then collecting the supernatant;

[0042] (4) concentrating the supernatant under reduced pressure until the relative density is 1.12-1.15 to obtain a concentrated solution;

[0043] (5) Add 2 times the weight of water to the concentrate, stir for 3 hours, and then refrigerate for 24 hours, and collect the supernatant to obtain the Ziziphus jujuba seed extract and the lemon balm extract.

[0044] The method for preparing the composite health product based on γ-aminobutyric acid comprises the following steps:

[0045] (1) Mix the Chinese jujube seed extract, lemon balm extract, B vitamins, γ-aminobutyric acid, and natural fructose according to the formula, and stir at a low speed for 20 minutes until a uniform powdery material is formed;

[0046] (2) adding a small amount of water and ethanol to the product obtained in step (1) under the condition that the ambient temperature does not exceed 25° C. and the relative humidity does not exceed 60%, stirring while adding, and granulating until a granular material is formed;

[0047] (3) drying the product obtained in step (2) at 40° C. until the moisture content drops below 5%;

[0048] (4) The product obtained in step (3) is sieved by a sieving machine to collect particles with a particle size between 0.5 and 2.0 mm to obtain a composite health product based on γ-aminobutyric acid.

[0049] Example 3

[0050] A composite health product based on gamma-aminobutyric acid comprises the following components in percentage by weight: gamma-aminobutyric acid: 25%; spinosa jujube seed extract: 8%; lemon balm extract: 5%; B vitamins: 6%; and natural fructose: 56%.

[0051] Wherein, the Chinese date seed extract and lemon balm extract are prepared by the following method:

[0052] (1) crushing the Chinese date seeds and lemon balm to a particle size of 100-200 mesh, adding 6 times the weight of each Chinese medicine and 70% ethanol for reflux extraction, and extracting twice, each time for 2 hours;

[0053] (2) concentrating the combined extracts under reduced pressure until an extract having a relative density of 1.12-1.15 is obtained;

[0054] (3) adding ethanol to the extract to adjust the ethanol content to 70%, leaving it to stand for 24 hours and then collecting the supernatant;

[0055] (4) concentrating the supernatant under reduced pressure until the relative density is 1.12-1.15 to obtain a concentrated solution;

[0056] (5) adding 2.5 times the weight of water to the concentrate, stirring for 3.5 hours, and then standing and refrigerating for 24 hours, taking the supernatant to obtain the jujube seed extract and the lemon balm extract.

[0057] The method for preparing the composite health product based on γ-aminobutyric acid comprises the following steps:

[0058] (1) Mixing the Chinese jujube seed extract, lemon balm extract, B vitamins, γ-aminobutyric acid, and natural fructose according to the formula, and stirring at a low speed for 30 minutes until a uniform powdery material is formed;

[0059] (2) adding a small amount of water and ethanol to the product obtained in step (1) under the condition that the ambient temperature does not exceed 25° C. and the relative humidity does not exceed 60%, stirring while adding, and granulating until a granular material is formed;

[0060] (3) drying the product obtained in step (2) at 50° C. until the moisture content drops below 5%;

[0061] (4) The product obtained in step (3) is sieved by a sieving machine to collect particles with a particle size between 0.5 and 2.0 mm to obtain a composite health product based on γ-aminobutyric acid.

[0062] Experiment 1: Mental stress detection

[0063] Healthy adult mice of a single sex were selected, and a negative control group and three experimental groups with different feeding amounts were set up, each containing 10 to 15 mice. The mice in the negative control group were fed ordinary feed every day, while the mice in the experimental groups were fed a compound health supplement based on γ-aminobutyric acid at 1 / 2, 1, and 2 times the amount of the control group. After one month, the preference of mice for bright and dark environments was observed through a dark avoidance experiment to assess their anxiety levels. The results are as follows:

[0064] Compared with the control group, the mental stress level of mice in the experimental group was reduced, especially the anxiety level of mice in the medium and high dose groups decreased significantly.

[0065] Experiment 2: Sleep quality detection

[0066] Healthy adult mice of a single sex were selected, and a negative control group and three experimental groups with different feeding amounts were set up, each containing 10 to 15 mice. The mice in the negative control group were fed ordinary feed every day, while the mice in the experimental groups were fed a compound health supplement based on γ-aminobutyric acid at 1 / 2, 1, and 2 times the amount of the control group. After one month, the sleep quality of the mice was evaluated by monitoring their sleep duration, and the results were as follows:

[0067] Compared with the control group, the mice in the experimental group had increased sleep duration, indicating improved sleep quality.

[0068] Experiment 3: Weight measurement

[0069] Healthy adult mice of a single sex were selected, and a negative control group and three experimental groups with different feeding amounts were set up, each containing 10 to 15 mice. The mice in the negative control group were fed ordinary feed every day, while the mice in the experimental groups were fed a compound health supplement based on γ-aminobutyric acid at 1 / 2, 1, and 2 times the amount of the control group's feeding amount. After one month, the weight changes of the mice were recorded, and the results are as follows:

[0070] Compared with the control group, the experimental group was able to increase the body weight of mice, indicating that its nutritional components were more adequate.

[0071] The above content is a further detailed description of the present invention in combination with specific implementation methods. It cannot be considered that the specific implementation of the present invention is limited to these descriptions. For ordinary technicians in the technical field to which the present invention belongs, simple modifications and substitutions made without departing from the concept of the present invention should be deemed to belong to the scope of protection of the present invention.

Claims

1. A composite health product based on γ-aminobutyric acid, It is characterized in that The invention comprises the following components in weight percentage: γ-aminobutyric acid: 10-30%; jujube seed extract: 5-15%; lemon balm extract: 3-10%; B vitamins: 2-8%; and natural fructose: 50-70%.

2. The composite health product based on γ-aminobutyric acid according to claim 1, It is characterized in that The invention comprises the following components in weight percentage: γ-aminobutyric acid: 20%; Ziziphus jujuba seed extract: 10%; lemon balm extract: 6%; B vitamins: 5%; and natural fructose: 59%.

3. The composite health product based on γ-aminobutyric acid according to claim 1 or 2, It is characterized in that The Chinese date seed extract and lemon balm extract are both prepared by the following method: (1) crushing the Chinese date seeds and lemon balm to a particle size of 100-200 mesh, adding 4-6 times the weight of each Chinese medicine and 70-75% ethanol for reflux extraction, and extracting twice, each time for 1-2 hours; (2) concentrating the combined extracts under reduced pressure until an extract having a relative density of 1.12-1.15 is obtained; (3) adding ethanol to the extract to adjust the ethanol content to 65%-75%, leaving it to stand for 24 hours and then collecting the supernatant; (4) concentrating the supernatant under reduced pressure until the relative density is 1.12-1.15 to obtain a concentrated solution; (5) adding 2-3 times the weight of water to the concentrate, stirring for 3-4 hours, and then standing and refrigerating for 24 hours, taking the supernatant to obtain the Ziziphus jujuba seed extract and the lemon balm extract.

4. The composite health product based on γ-aminobutyric acid according to claim 1 or 2, It is characterized in that The B vitamins include thiamine, riboflavin, niacin, pantothenic acid, pyridoxine, biotin, folic acid, and cobalamin.

5. The method for preparing the composite health product based on γ-aminobutyric acid according to any one of claims 1 to 4, It is characterized in that The following steps are involved: (1) Mix the Chinese jujube seed extract, lemon balm extract, B vitamins, γ-aminobutyric acid and natural fructose according to the formula, and stir at a low speed for 15-30 minutes until a uniform powdery material is formed; (2) adding a small amount of water and ethanol to the product obtained in step (1) under the condition that the ambient temperature does not exceed 25° C. and the relative humidity does not exceed 60%, stirring while adding, and granulating until a granular material is formed; (3) drying the product obtained in step (2) at a temperature of 40-50° C. until the moisture content drops below 5%; (4) The product obtained in step (3) is sieved by a sieving machine to collect particles with a particle size between 0.5 and 2.0 mm to obtain a composite health product based on γ-aminobutyric acid.