Intracardiac and extracardiac membrane combined radio-frequency pulse ablation catheter and treatment method thereof

Abstract

The invention relates to an endocardium and endocardium combined radio-frequency pulse ablation catheter and a treatment method thereof. The endocardium and endocardium combined radio-frequency pulse ablation catheter comprises an ablation catheter body, an ablation electrode positive electrode is arranged at one end of the ablation catheter body, the ablation electrode positive electrode acts on the epicardium, an ablation electrode negative electrode acts on the endocardium, and the ablation electrode positive electrode and the ablation electrode negative electrode are connected with a signal generator; the combined radio-frequency pulse ablation catheter for the internal and external cardiopulmonary membranes has the combination of a radio-frequency ablation mode and a pulse ablation mode, not only can the superficial internal and external cardiopulmonary membrane pathological tissues be ablated, but also the pathological tissues at deep cardiac muscle parts can be ablated, different ablation methods are used for the pathological tissues with different attributes, and the ablation efficiency is greatly improved. And a more targeted treatment effect is achieved.

Description

Technical Field

[0001] The invention relates to a radio frequency pulse ablation catheter, in particular to an endocardial and endocardial combined radio frequency pulse ablation catheter and a treatment method thereof. Background Art

[0002] Pulse ablation and radiofrequency ablation are two common medical technologies used for tumor treatment, pain management, and other medical purposes. In addition, radiofrequency ablation can also be used for cardiac radiofrequency ablation to treat arrhythmias. In summary, both pulse ablation and radiofrequency ablation are effective treatments, but the choice should be weighed based on personal circumstances and doctor's advice to achieve better treatment results. Ablation catheters are widely used in modern medicine to treat a variety of diseases, such as arrhythmias, tumors, and pain. By using ablation catheters, doctors can perform surgery without cutting into the patient's body, thereby reducing surgical trauma and recovery time.

[0003] Pulsed field ablation (PFA) is a major advance in catheter ablation of atrial fibrillation in recent years. Its principle is to induce cell apoptosis by applying microsecond or even nanosecond high-voltage electric pulses to tissues. Compared with traditional radiofrequency and cryotherapy, pulsed field ablation can further improve the efficiency and safety of catheter ablation of atrial fibrillation because of its very short discharge time and the fact that it does not rely on thermal effects to cause tissue damage.

[0004] In the prior art, radiofrequency energy is applied to the endocardial or epicardial surface of the heart through the electrodes of the ablation catheter, and grounded through the electrode pads placed on the patient's skin. In this case, the radiofrequency energy is dispersed in the tissue between the end of the catheter (i.e., the tip electrode) and the electrode pad. The basic principles of tumor electric field therapy are based on the fact that electric fields have an inhibitory and destructive effect on tumor cell mitosis. Generally, the electric field generated by an electric signal of 50kHz-300kHz can be used to inhibit the rapid growth of patient tumor cells to achieve a therapeutic effect.

[0005] The endocardium is a smooth membrane covering the inner surface of the heart cavity, which is continuous with the endothelium of the blood vessels entering and leaving the heart. It is composed of the endothelium and the subendothelial layer. The epicardium is the visceral layer of the serous pericardium, which wraps around the surface of the myocardium. The surface is covered with a layer of mesothelium, which is composed of flat epithelial cells.

[0006] The existing ablation catheter can effectively ablate superficial arrhythmias in the endocardium, but when lesions occur in deep myocardial areas, the existing ablation catheter is difficult to effectively treat. At the same time, the existing ablation temperature monitoring is easily interfered by electromagnetic waves or electric currents, resulting in temperature distortion. Summary of the invention

[0007] The present invention designs a combined endocardial and endocardial radiofrequency pulse ablation catheter and a treatment method thereof, which solves the following technical problems: (1) the ablation catheter of the prior art can effectively ablate superficial arrhythmias, but when lesions occur in deep myocardial areas or endocardium, the ablation catheter of the prior art is difficult to perform effective treatment; and (2) the existing ablation temperature monitoring is easily interfered by electromagnetic waves or electric current, resulting in temperature measurement distortion.

[0008] In order to solve the above-mentioned technical problems, the present invention adopts the following solutions: A combined endocardial and endocardial radiofrequency pulse ablation catheter includes an ablation catheter, one end of which is provided with an ablation electrode positive electrode, the ablation electrode positive electrode acts on the epicardium, the ablation electrode negative electrode acts on the endocardium, the ablation electrode positive electrode and the ablation electrode negative electrode are both connected to a signal generator, and the catheter is characterized in that: the ablation electrode positive electrode and the ablation electrode negative electrode can switch between radiofrequency ablation mode and pulse ablation mode; the radiofrequency ablation mode ablates superficial lesions of the endocardium and endocardium, and the pulse ablation mode ablates lesions of the deep myocardium of the endocardium and endocardium. A mobile temperature sensor is provided in the inner cavity of the ablation catheter, and the electromagnetic shielding insulation structure of the inner cavity of the ablation catheter prevents the electromagnetic waves or currents generated by the ablation electrode from affecting the temperature of the mobile temperature sensor in the inner cavity; the mobile temperature sensor is extended out of the ablation catheter through the action of a traction mechanism to contact the lesion tissue; the mobile temperature sensor can monitor the temperature of the center and edge of the lesion tissue to ensure the quality of ablation.

[0009] Preferably, the traction mechanism acts to move the temperature sensor out of the ablation catheter and then passes through the through hole on the positive electrode of the ablation electrode to finally enter the central area of ​​the diseased tissue. It also synchronously drives multiple edge area temperature sensors to extend out of the ablation catheter and pass through the through hole on the positive electrode of the ablation electrode and finally contact the edge area of ​​the diseased tissue to monitor the external edge area of ​​the diseased tissue; the central area temperature sensor on the mobile temperature sensor enters the central area of ​​the diseased tissue to monitor the ablation temperature inside the diseased tissue, and multiple edge area temperature sensors and the central area temperature sensor jointly monitor the ablation situation of the diseased tissue.

[0010] Preferably, the ablation catheter is provided with a plurality of temperature sensor passage oblique tubes, and the plurality of temperature sensor passage oblique tubes are located in the internal cavity of the ablation catheter, and the opening of the temperature sensor passage oblique tube on the ablation catheter is provided with an openable shielding cover; an edge area temperature sensor is provided in each temperature sensor passage oblique tube, and the length of the edge area temperature sensor is greater than the length of the temperature sensor passage oblique tube, and a sensor reset spring is connected between the temperature sensor passage oblique tube and the edge area temperature sensor; when the sensor reset spring is not deformed, the portion of the edge area temperature sensor exposed outside the temperature sensor passage oblique tube is located in the internal cavity of the ablation catheter, and the conical front end of the center area temperature sensor gradually pushes the edge area temperature sensor to extend outward, pushes open the shielding cover and contacts the edge position of the diseased tissue during the forward movement, and the sensor reset spring is synchronously deformed at this time.

[0011] Preferably, the edge area temperature measuring sensor includes a main body and a foldable temperature measuring unit. The foldable temperature measuring unit is hinged to the main body through a torsion spring. When the foldable temperature measuring unit leaves the inclined tube of the temperature measuring sensor, it unfolds to increase the detection range of the edge area temperature measuring sensor, which is suitable for diseased tissue with a large area.

[0012] Preferably, a movable shielding cover is provided at an opening at one end of the ablation catheter, and when the mobile temperature measuring sensor moves forward, the movable shielding cover can be opened and enter into the passage hole on the positive pole of the ablation electrode.

[0013] Preferably, the movable shielding cover is composed of at least two pieces, each movable shielding cover is located in the guide groove of the ablation catheter and is connected to the guide groove through a cover return spring; a push-open groove is provided at the connection between the movable shielding covers, and the end of the mobile temperature sensor can act on the push-open groove to push all the movable shielding covers open.

[0014] Preferably, the traction mechanism is a U-shaped structure, and a first traction rack is provided on one U-shaped arm of the traction mechanism, and a first rack is provided on one side of the mobile temperature sensor. The first traction rack is meshed with the first rack through a first gear, and the first gear is installed on the first rotating shaft, and both ends of the first rotating shaft are fixed on the ablation catheter; a second traction rack is provided on the other U-shaped arm of the traction mechanism, and a second rack is provided on the other side of the mobile temperature sensor. The second traction rack is meshed with the second rack through a second gear, and the second gear is installed on the second rotating shaft, and both ends of the second rotating shaft are fixed on the ablation catheter; the traction mechanism is connected to one end of the traction rope, and when the traction rope is pulled to make the traction mechanism move backward, the mobile temperature sensor moves forward.

[0015] Preferably, it also includes a three-dimensional mapping device and a driving motor, which can determine the penetration depth of the mobile temperature sensor on the diseased tissue by analyzing the electrocardiogram signal; the ablation catheter is connected to one end of the guide sheath, the traction rope is located in the guide sheath, and the other end of the guide sheath is connected to the driving motor; the rotor of the driving motor is connected to the other end of the traction rope, and the control unit determines the penetration depth of the central area temperature sensor according to the center position of the diseased tissue calculated by the three-dimensional mapping device, starts the driving motor to pull the traction rope to move, and ensures that the central area temperature sensor is located at the center position of the diseased tissue.

[0016] Preferably, an annular guide bracket is provided inside the ablation catheter, a guide cavity is provided in the annular guide bracket, a baffle on the mobile temperature sensor is located in the guide cavity, and a spring is provided in the guide cavity; when the central area temperature sensor is moved out of the ablation catheter, the spring is squeezed and deformed; when the driving motor releases the traction rope, the spring resets so that the mobile temperature sensor returns to the ablation catheter.

[0017] A treatment method of endocardial combined radiofrequency pulse ablation catheter comprises the following steps: Step 1: Determine the location of superficial endocardial and endocardial lesions, insert the ablation catheter into the heart cavity where the lesions are located, so that the positive pole of the ablation electrode acts on the epicardium and the negative pole of the ablation electrode acts on the endocardium, start the radiofrequency ablation mode, and the radiofrequency energy output by the positive and negative poles acts on the superficial endocardial and endocardial lesions for ablation.

[0018] Or / and, determine the location of the diseased tissue of the endocardium in the deep myocardium, send the ablation catheter into the heart cavity where the diseased tissue is located, so that the positive pole of the ablation electrode acts on the epicardium and the negative pole of the ablation electrode acts on the endocardium, start the pulse ablation mode, and the pulse current energy output by the positive and negative poles acts on the diseased tissue of the endocardium and endocardium in the deep myocardium to ablate.

[0019] Step 2, turn off the signal generator, start the drive motor to pull the traction rope, and move the temperature sensor to extend the ablation catheter through the traction mechanism, wherein the central area temperature sensor enters the center position of the diseased tissue according to the position determined by the three-dimensional mapping equipment to measure the temperature, and multiple edge area temperature sensors extend out of the ablation catheter to contact the edge area of ​​the diseased tissue; multiple edge area temperature sensors and central area temperature sensors jointly monitor the ablation of the diseased tissue; when the temperatures measured by multiple edge area temperature sensors and central area temperature sensors reach the predetermined value, it indicates that the ablation of both deep and superficial diseased tissues is complete.

[0020] The endocardial combined radiofrequency pulse ablation catheter and its treatment method have the following beneficial effects: (1) The combined endocardial and endocardial radiofrequency pulse ablation catheter of the present invention has a combination of radiofrequency ablation mode and pulse ablation mode, which can not only ablate superficial endocardial and endocardial diseased tissues, but also ablate diseased tissues in deep myocardial areas. Different ablation methods are used for diseased tissues with different properties, which has a more targeted treatment effect.

[0021] (2) After the pulse and radiofrequency ablation is completed, the present invention can immediately release the mobile temperature sensor, and monitor the complex deep part and edge of the diseased tissue through multiple temperature sensors to ensure the quality of ablation. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 : Schematic diagram of the connection between the endocardial and endocardial combined radiofrequency pulse ablation catheter and the signal generator of the present invention; Figure 2 : Schematic diagram of the connection of components of the endocardial and endocardial combined radiofrequency pulse ablation catheter of the present invention; Figure 3 : Schematic diagram of the internal structure of the endocardial and endocardial combined radiofrequency pulse ablation catheter of the present invention; Figure 4 : Figure 3 The enlarged schematic diagram at A in the middle; Figure 5 : Schematic diagram of the structure of the movable shielding cover at the bottom of the endocardial and endocardial combined radiofrequency pulse ablation catheter of the present invention; Figure 6 : Schematic diagram of the temperature measurement without extending the edge area temperature measurement sensor embodiment 1 of the present invention; Figure 7 : Schematic diagram of the edge area temperature measurement sensor embodiment 1 of the present invention extending out for temperature measurement; Figure 8 : Schematic diagram of the temperature measurement without extending the edge area temperature measurement sensor embodiment 2 of the present invention; Fig. 9 : Schematic diagram of the edge area temperature measurement sensor embodiment 2 of the present invention extending out for temperature measurement; Fig.10 : Schematic diagram of the operation of the endocardial and endocardial combined radiofrequency pulse ablation catheter of the present invention; Fig.11 : Schematic diagram of the traction mechanism structure of the endocardial and endocardial combined radiofrequency pulse ablation catheter of the present invention; Fig.12 : Schematic diagram of the internal structure of the annular guide bracket in the present invention.

[0023] Description of reference numerals: 1—ablation catheter body; 12—temperature sensor passage oblique tube; 121—sensor reset spring; 122—shielding cover; 13—electrode wire; 14—annular guide bracket; 141—guide cavity; 142—spring; 15—edge area temperature sensor; 151—foldable temperature measurement unit; 152—torsion spring; 16—movable shielding cover; 17—cover reset spring; 18—top opening groove; 3—movable temperature sensor; 31—center area temperature sensor; 33—first tooth 1—second rack; 34—second rack; 35—blocking piece; 4—traction mechanism; 41—traction rope; 42—traction first rack; 43—first gear; 431—first rotating shaft; 44—traction second rack; 45—second gear; 451—second rotating shaft; 5—guide sheath; 6—drive motor; 7—operating handle; 8—lesioned tissue; 9—signal generator; 91—negative electrode of ablation electrode; 92—positive electrode of ablation electrode; 921—passage hole; 93—endocardium; 94—epicardium. DETAILED DESCRIPTION

[0024] Combine the following Figures 1 to 12 , the present invention is further described: like Figure 1-Figure 2 and Fig.10 As shown, the combined endocardial and endocardial radiofrequency pulse ablation catheter of the present invention comprises an ablation catheter body 1, one end of which is provided with an ablation electrode positive electrode 92, the ablation electrode positive electrode 92 acts on the epicardium 94, the ablation electrode negative electrode 91 acts on the endocardium 93, the ablation electrode positive electrode 92 and the ablation electrode negative electrode 91 are connected to a signal generator 9, and the ablation electrode positive electrode 92 and the ablation electrode negative electrode 91 can switch between a radiofrequency ablation mode and a pulse ablation mode; the radiofrequency ablation mode ablates the superficial lesion tissue 8 of the endocardium and endocardium, and the pulse ablation mode ablates ... The ablation mode ablates the diseased tissue in the deep myocardium of the endocardium and endocardium; a mobile temperature sensor 3 is provided in the internal cavity of the ablation catheter body 1, and the electromagnetic shielding insulation structure of the internal cavity of the ablation catheter body 1 prevents the electromagnetic waves or currents generated by the ablation electrode from affecting the temperature of the mobile temperature sensor 3 in the internal cavity; the mobile temperature sensor 3 extends out of the ablation catheter body 1 through the action of the traction mechanism 4 to contact the diseased tissue 8; the mobile temperature sensor 3 can monitor the temperature of the center and edge of the diseased tissue 8 to ensure the quality of ablation. The mobile temperature sensor 3 includes a central area temperature sensor 31 and multiple edge area temperature sensors 15.

[0025] The traction mechanism 4 acts to move the temperature sensor 3 to extend out of the ablation catheter body 1 and then pass through the through hole 921 on the ablation electrode positive pole 92 to finally enter the central area of ​​the diseased tissue 8. It also synchronously drives multiple edge area temperature sensors 15 to extend out of the ablation catheter body 1 and pass through the through hole 921 on the ablation electrode positive pole 92 and finally contact the edge area of ​​the diseased tissue 8 to monitor the external edge area of ​​the diseased tissue; the central area temperature sensor 31 on the mobile temperature sensor 3 enters the central area of ​​the diseased tissue to monitor the internal ablation temperature of the diseased tissue, and multiple edge area temperature sensors 15 and the central area temperature sensor 31 jointly monitor the ablation condition of the diseased tissue.

[0026] like Figure 5 As shown, a movable shielding cover 16 is provided at an opening at one end of the ablation catheter body 1, and when the movable temperature sensor 3 moves forward, the movable shielding cover 16 can be opened and enter the passage hole 921 on the ablation electrode positive pole 92. The movable shielding cover 16 is composed of at least two pieces, each of which is located in the guide groove of the ablation catheter body 1 and connected to the guide groove through a cover return spring 17; a push-open groove 18 is provided at the connection between the movable shielding covers 16, and the end of the movable temperature sensor 3 can act on the push-open groove 18 to push all the movable shielding covers 16 away.

[0027] like Figure 6-Figure 7 As shown, the ablation catheter body 1 is provided with a plurality of temperature sensor passage oblique tubes 12, and the plurality of temperature sensor passage oblique tubes 12 are located in the internal cavity of the ablation catheter body 1, and the opening of the temperature sensor passage oblique tube 12 on the ablation catheter body 1 is provided with an openable shielding cover 122; an edge area temperature sensor 15 is provided in each temperature sensor passage oblique tube 12, and the length of the edge area temperature sensor 15 is greater than the length of the temperature sensor passage oblique tube 12, and a sensor reset spring 121 is connected between the temperature sensor passage oblique tube 12 and the edge area temperature sensor 15; when the sensor reset spring 121 is not deformed, the portion of the edge area temperature sensor 15 exposed outside the temperature sensor passage oblique tube 12 is located in the internal cavity of the ablation catheter body 1, and the conical front end of the center area temperature sensor 31 gradually pushes the edge area temperature sensor 15 outward to push open the shielding cover 122 and contact the edge position of the diseased tissue 8 during the forward movement, and the sensor reset spring 121 is synchronously deformed at this time.

[0028] like Figure 8-Figure 10 As shown, the edge area temperature measuring sensor 15 includes a main body and a foldable temperature measuring unit 151. The foldable temperature measuring unit 151 is hinged to the main body through a torsion spring 152. When the foldable temperature measuring unit 151 leaves the temperature sensor passage inclined tube 12, it unfolds to increase the detection range of the edge area temperature measuring sensor 15, which is suitable for diseased tissue with a large area.

[0029] like Fig.11As shown, the traction mechanism 4 is a U-shaped structure, and a first traction rack 42 is provided on one U-shaped arm of the traction mechanism 4, and a first rack 33 is provided on one side of the mobile temperature sensor 3. The first traction rack 42 is meshed with the first rack 33 through a first gear 43, and the first gear 43 is installed on a first rotating shaft 431, and both ends of the first rotating shaft 431 are fixed on the ablation catheter body 1; a second traction rack 44 is provided on the other U-shaped arm of the traction mechanism 4, and a second rack 34 is provided on the other side of the mobile temperature sensor 3. The second traction rack 44 is meshed with the second rack 34 through a second gear 45, and the second gear 45 is installed on a second rotating shaft 451, and both ends of the second rotating shaft 451 are fixed on the ablation catheter body 1; the traction mechanism 4 is connected to one end of the traction rope 41, and when the traction rope 41 is pulled to make the traction mechanism 4 move backward, the mobile temperature sensor 3 moves forward.

[0030] It also includes a three-dimensional mapping device and a driving motor 6, which can determine the penetration depth of the mobile temperature sensor 3 on the diseased tissue by analyzing the electrocardiogram signal; the ablation catheter body 1 is connected to one end of the guide sheath 5, the traction rope 41 is located in the guide sheath 5, and the other end of the guide sheath 5 is connected to the driving motor 6; the rotor of the driving motor 6 is connected to the other end of the traction rope 41, and the control unit determines the penetration depth of the central area temperature sensor 31 according to the center position of the diseased tissue calculated by the three-dimensional mapping device, starts the driving motor 6 to pull the traction rope 41 to move, and ensures that the central area temperature sensor 31 is located at the center position on the diseased tissue.

[0031] like Fig.12 As shown, an annular guide bracket 14 is provided inside the ablation catheter body 1, a guide cavity 141 is provided in the annular guide bracket 14, a baffle 35 on the mobile temperature sensor 3 is located in the guide cavity 141, and a spring 142 is provided in the guide cavity 141; when the central area temperature sensor 31 moves out of the ablation catheter body 1, the spring 142 is squeezed and deformed; when the driving motor 6 releases the traction rope 41, the spring 142 is reset so that the mobile temperature sensor 3 returns to the ablation catheter body 1.

[0032] The treatment method or control method of the endocardial combined radiofrequency pulse ablation catheter of the present invention comprises the following steps: Step 1, the first working mode: determine the location of the superficial endocardial and endocardial diseased tissue, and send the ablation catheter body 1 into the heart cavity where the diseased tissue is located, so that the ablation electrode positive electrode 92 acts on the epicardium 94 and the ablation electrode negative electrode 91 acts on the endocardium 93, and start the radiofrequency ablation mode. The radiofrequency energy output by the positive and negative electrodes acts on the superficial endocardial and endocardial diseased tissue for ablation.

[0033] Or / and, the second working mode: determine the location of the diseased tissue of the endocardium in the deep myocardium, send the ablation catheter body 1 into the heart cavity where the diseased tissue is located, so that the positive pole 92 of the ablation electrode acts on the epicardium 94 and the negative pole 91 of the ablation electrode acts on the endocardium 93, start the pulse ablation mode, and the pulse current energy output by the positive and negative poles acts on the diseased tissue of the endocardium and endocardium in the deep myocardium to ablate.

[0034] Step 2, turn off the signal generator 9, start the drive motor 6 to pull the traction rope 41, and the mobile temperature sensor 3 is extended out of the ablation catheter body 1 through the action of the traction mechanism 4, wherein the central area temperature sensor 31 enters the center position of the diseased tissue according to the position determined by the three-dimensional mapping equipment to measure the temperature, and multiple edge area temperature sensors 15 are extended out of the ablation catheter body 1 to contact the edge area of ​​the diseased tissue; multiple edge area temperature sensors 15 and central area temperature sensors 31 jointly monitor the ablation of the diseased tissue; when the temperatures measured by multiple edge area temperature sensors 15 and central area temperature sensors 31 reach the predetermined value, it indicates that the ablation of both deep and superficial diseased tissues is complete.

[0035] Due to the complex internal structure of deep-seated lesion tissue, fibrosis and calcification may exist, and these lesions do not absorb radio frequency pulse energy well, that is, the lesion tissue may not reach the predetermined ablation temperature before the ablation surgery is completed. The central area temperature sensor 31 of the present invention can ensure that the mobile temperature sensor obtains the temperature value of the center of the lesion tissue. At the same time, multiple edge area temperature sensors 15 can be used to monitor the temperature around the entire lesion tissue. When the center and edge temperatures reach the preset values, it can be clearly determined that the ablation has met the surgical requirements, and the two defects of carbonization and insufficient ablation can be avoided.

[0036] The present invention is described above by way of example in conjunction with the accompanying drawings. It is obvious that the implementation of the present invention is not limited to the above-mentioned method. As long as various improvements are made using the method concept and technical solution of the present invention, or the concept and technical solution of the present invention are directly applied to other occasions without improvement, they are all within the protection scope of the present invention.

Claims

1. An endocardial combined radiofrequency pulse ablation catheter, comprising an ablation catheter body (1), characterized in that: An ablation electrode positive electrode (92) is provided at one end of the ablation catheter body (1). The ablation electrode positive electrode (92) acts on the epicardium (94), and the ablation electrode negative electrode (91) acts on the endocardium (93). Both the ablation electrode positive electrode (92) and the ablation electrode negative electrode (91) are connected to a signal generator (9). The ablation electrode positive electrode (92) and the ablation electrode negative electrode (91) can switch between a radiofrequency ablation mode and a pulse ablation mode. The radiofrequency ablation mode ablates superficial lesion tissue (8) of the endocardium and esophagus, and the pulse ablation mode ablates lesion tissue in the deep myocardium of the endocardium and esophagus.

2. The endocardial combined radiofrequency pulse ablation catheter according to claim 1, characterized in that: A mobile temperature sensor (3) is provided in the internal cavity of the ablation catheter body (1); the electromagnetic shielding insulation structure of the internal cavity of the ablation catheter body (1) prevents electromagnetic waves or currents generated by the ablation electrode from affecting the temperature of the mobile temperature sensor (3) in the internal cavity; the mobile temperature sensor (3) is extended out of the ablation catheter body (1) and contacts the diseased tissue (8) through the action of a traction mechanism (4); the mobile temperature sensor (3) can monitor the temperature of the center and edge of the diseased tissue (8) to ensure the quality of ablation.

3. The endocardial combined radiofrequency pulse ablation catheter according to claim 2, characterized in that: The traction mechanism (4) acts to move the temperature sensor (3) out of the ablation catheter body (1) and then passes through the through hole (921) on the positive electrode (92) of the ablation electrode to finally enter the central area of ​​the diseased tissue (8), and also synchronously drives the plurality of edge area temperature sensors (15) to extend out of the ablation catheter body (1) and finally contact the edge area of ​​the diseased tissue (8) to monitor the outer edge area of ​​the diseased tissue; the central area temperature sensor (31) on the mobile temperature sensor (3) enters the central area of ​​the diseased tissue to monitor the internal ablation temperature of the diseased tissue, and the plurality of edge area temperature sensors (15) and the central area temperature sensor (31) jointly monitor the ablation status of the diseased tissue.

4. The endocardial combined radiofrequency pulse ablation catheter according to claim 3, characterized in that: The ablation catheter body (1) is provided with a plurality of temperature sensor passage oblique tubes (12), the plurality of temperature sensor passage oblique tubes (12) being located in the internal cavity of the ablation catheter body (1), and the opening of the temperature sensor passage oblique tubes (12) on the ablation catheter body (1) is provided with an openable shielding cover (122); each temperature sensor passage oblique tube (12) is provided with an edge region temperature sensor (15), the length of the edge region temperature sensor (15) is greater than the length of the temperature sensor passage oblique tube (12), and the temperature sensor passage oblique tube (12) and the edge region temperature sensor (15) are connected to each other. A sensor reset spring (121) is connected between the regional temperature sensors (15); when the sensor reset spring (121) is not deformed, the portion of the edge region temperature sensor (15) exposed outside the temperature sensor passage oblique tube (12) is located in the internal cavity of the ablation catheter body (1), and the conical front end of the central region temperature sensor (31) gradually pushes the edge region temperature sensor (15) outward during the forward movement, pushes open the shielding cover (122) and contacts the edge of the diseased tissue (8), and at this time, the sensor reset spring (121) is synchronously deformed.

5. The endocardial combined radiofrequency pulse ablation catheter according to claim 4, characterized in that: The edge region temperature measuring sensor (15) comprises a main body and a foldable temperature measuring unit (151); the foldable temperature measuring unit (151) is hinged to the main body via a torsion spring (152); when the foldable temperature measuring unit (151) leaves the temperature measuring sensor passage oblique tube (12), it unfolds to increase the detection range of the edge region temperature measuring sensor (15), which is suitable for lesion tissue with a large area.

6. The endocardial combined radiofrequency pulse ablation catheter according to claim 5, characterized in that: A movable shielding cover (16) is provided at an opening at one end of the ablation catheter body (1); when the movable temperature measuring sensor (3) moves forward, the movable shielding cover (16) can be opened and enter the passage hole (921) on the ablation electrode positive pole (92).

7. The endocardial combined radiofrequency pulse ablation catheter according to claim 6, characterized in that: The movable shielding cover (16) is composed of at least two pieces, each movable shielding cover (16) is located in a guide groove of the ablation catheter body (1) and is connected to the guide groove via a cover return spring (17); a push-open groove (18) is provided at the connection between the movable shielding covers (16), and the end of the movable temperature sensor (3) can act on the push-open groove (18) to push all the movable shielding covers (16) away.

8. The endocardial combined radiofrequency pulse ablation catheter according to claim 7, characterized in that: The traction mechanism (4) is a U-shaped structure. A first traction rack (42) is provided on one U-shaped arm of the traction mechanism (4). A first rack (33) is provided on one side of the mobile temperature measuring sensor (3). The first traction rack (42) is meshed with the first rack (33) via a first gear (43). The first gear (43) is mounted on a first rotating shaft (431). Both ends of the first rotating shaft (431) are fixed on the ablation catheter body (1). A second traction rack (42) is provided on the other U-shaped arm of the traction mechanism (4). 44), a second rack (34) is provided on the other side of the mobile temperature sensor (3), the second rack (44) is pulled to mesh with the second rack (34) through a second gear (45), the second gear (45) is mounted on a second rotating shaft (451), and both ends of the second rotating shaft (451) are fixed to the ablation catheter body (1); the traction mechanism (4) is connected to one end of the traction rope (41), and when the traction rope (41) is pulled to cause the traction mechanism (4) to move backward, the mobile temperature sensor (3) moves forward.

9. The endocardial combined radiofrequency pulse ablation catheter according to claim 8, characterized in that: It also includes a three-dimensional mapping device and a drive motor (6), which can determine the penetration depth of the mobile temperature sensor (3) on the diseased tissue by analyzing the electrocardiogram signal; the ablation catheter body (1) is connected to one end of the guide sheath (5), the traction rope (41) is located in the guide sheath (5), and the other end of the guide sheath (5) is connected to the drive motor (6); the rotor of the drive motor (6) is connected to the other end of the traction rope (41), the control unit determines the penetration depth of the central area temperature sensor (31) according to the central position of the diseased tissue calculated by the three-dimensional mapping device, starts the drive motor (6) to pull the traction rope (41) to move, and ensures that the central area temperature sensor (31) is located at the central position on the diseased tissue; An annular guide bracket (14) is provided inside the ablation catheter body (1), a guide cavity (141) is provided in the annular guide bracket (14), a baffle (35) on the mobile temperature sensor (3) is located in the guide cavity (141), and a spring (142) is provided in the guide cavity (141); when the central area temperature sensor (31) moves out of the ablation catheter body (1), the spring (142) is squeezed and deformed; when the drive motor (6) releases the traction rope (41), the spring (142) is reset so that the mobile temperature sensor (3) returns to the ablation catheter body (1).

10. A therapeutic method of endocardial combined radiofrequency pulse ablation catheter according to any one of claims 3 to 9, comprising the following steps: Step 1: determine the location of superficial endocardial and endocardial diseased tissue, insert the ablation catheter body (1) into the heart cavity where the diseased tissue is located, so that the ablation electrode positive electrode (92) acts on the epicardium (94) and the ablation electrode negative electrode (91) acts on the endocardium (93), start the radiofrequency ablation mode, and the radiofrequency energy output by the positive and negative electrodes acts on the superficial endocardial and endocardial diseased tissue to ablate; or / and, determining the location of the diseased tissue of the endocardium in the deep myocardium, inserting the ablation catheter body (1) into the heart cavity where the diseased tissue is located, so that the ablation electrode positive electrode (92) acts on the epicardium (94) and the ablation electrode negative electrode (91) acts on the endocardium (93), starting the pulse ablation mode, and the pulse current energy output by the positive and negative electrodes acts on the diseased tissue of the endocardium and endocardium in the deep myocardium to ablate; Step 2, turn off the signal generator (9), start the drive motor (6) to pull the traction rope (41), and the mobile temperature sensor (3) extends out of the ablation catheter body (1) through the action of the traction mechanism (4), wherein the central area temperature sensor (31) of the mobile temperature sensor (3) enters the central position of the diseased tissue according to the position determined by the three-dimensional mapping device to measure the temperature, and multiple edge area temperature sensors (15) extend out of the ablation catheter body (1) to contact the edge area of ​​the diseased tissue; the multiple edge area temperature sensors (15) and the central area temperature sensor (31) jointly monitor the ablation of the diseased tissue; when the temperatures measured by the multiple edge area temperature sensors (15) and the central area temperature sensor (31) reach a predetermined value, it indicates that the ablation of the deep and superficial diseased tissues is complete.

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