Female antibacterial liquid containing fructus cnidii extract and preparation method thereof

Abstract

The invention discloses female antibacterial liquid containing a fructus cnidii extract and a preparation method of the female antibacterial liquid. Comprising the following raw materials in percentage by weight: 3% of a radix sophorae flavescentis extract, 3% of a fructus cnidii extract, 0.014% of a tree bark extract, 0.014% of a chrysanthemum indicum extract, 0.014% of a liquorice root extract, 0.014% of a honeysuckle flower extract, 0.014% of a coptis chinensis extract, 10% of rosa damascena flower water, 0.8% of butanediol, 5% of bis-PEG-15 methyl ether polydimethylsiloxane, 3% of cocoyl glutamic acid and 7% of triethanolamine. The composition comprises the following components in percentage by weight: 0.00045% of menthyl lactate, 0.01% of beta-nicotinamide mononucleotide, 0.02% of pyrroloquinoline quinone disodium salt and 68.09955% of water. By elaborately selecting various natural plant extracts and optimizing the proportion, the antibacterial effect is remarkably improved, and meanwhile, the antibacterial lotion is mild and non-irritant to vagina and is suitable for sensitive skin. The extraction method of the extract strictly controls the temperature and time, ensures that the purity of the extract is not lower than 90%, ensures the quality and safety of the product, and ensures the quality of the product through careful process control.

Description

Technical Field

[0001] The invention relates to the technical field of personal care products, in particular to a female antibacterial liquid containing a Cnidium monnieri extract and a preparation method thereof. Background Art

[0002] With the improvement of people's living standards and the enhancement of health awareness, the demand for personal care products is also growing, especially for products for female private parts care. The female private parts of the vagina are more sensitive and easily affected by the external environment and cause infections and other problems. Therefore, there is a wide demand in the market for female care products with antibacterial function and mild and non-irritating to the vagina.

[0003] Although there are many types of existing female antibacterial liquid products, there are still certain deficiencies in terms of antibacterial effect, safety of ingredients and mildness. For example, some products contain chemical preservatives and highly irritating ingredients, which may cause adverse effects on the vagina after long-term use; other products may not achieve the ideal antibacterial effect due to their single ingredients. Therefore, there is an urgent need for a female antibacterial liquid containing Cnidium monnieri extract and a preparation method thereof. Summary of the invention

[0004] The technical problem to be solved by the present invention is to overcome the above technical defects and provide a female antibacterial liquid containing Cnidium monnieri extract and a preparation method thereof.

[0005] In order to solve the above problems, the technical solution of the present invention is a female antibacterial liquid containing Cnidium monnieri extract, comprising the following raw materials in percentage by weight:

[0006] Sophora flavescens extract, 3%;

[0007] Cnidium monnieri extract, 3%;

[0008] Cinchona bark extract, 0.014%;

[0009] Wild chrysanthemum extract, 0.014%;

[0010] Licorice extract, 0.014%;

[0011] Honeysuckle flower extract, 0.014%;

[0012] Coptis chinensis extract, 0.014%;

[0013] Rosa damascena flower water, 10%;

[0014] Butanediol, 0.8%;

[0015] Bis-PEG-15 methyl ether dimethicone, 5%;

[0016] Cocoyl glutamate, 3%;

[0017] triethanolamine, 7%;

[0018] Menthol lactate, 0.00045%;

[0019] β-Nicotinamide mononucleotide, 0.01%;

[0020] Pyrroloquinoline quinone disodium salt, 0.02%;

[0021] Water, 68.09955%.

[0022] Furthermore, the temperature is 60-80° C., the extraction time is 2-4 hours, and the purity requirement is not less than 90%.

[0023] Furthermore, the extraction method of the Cnidium monnieri extract is as follows: after crushing the Cnidium monnieri raw material, using ethanol or water as a solvent, extracting for a period of time at a certain temperature, filtering and concentrating to obtain the Cnidium monnieri extract.

[0024] Furthermore, the extraction methods of the sophora flavescens extract, the cinchona bark extract, the wild chrysanthemum extract, the liquorice extract, the honeysuckle flower extract and the coptis chinensis extract are all water extraction or ethanol extraction, and the purity of each extract is not less than 90%.

[0025] A method for preparing a female antibacterial liquid containing a Cnidium monnieri extract comprises the following steps:

[0026] S1, extraction, wherein the raw materials of Cnidium monnieri, Sophora flavescens, Cina chinensis bark, Chrysanthemum indica, Licorice root, Honeysuckle flower and Coptis chinensis are respectively extracted by water extraction or ethanol extraction, and the purity of each extract is not less than 90%;

[0027] S2, mixing, mixing the Sophora flavescens extract, the Cnidium monnieri extract, the Cinchona bark extract, the Chrysanthemum indici extract, the Licorice extract, the Honeysuckle extract and the Coptis chinensis extract in proportion to obtain a mixed extract;

[0028] S3, adding damask rose flower water, butylene glycol, bis-PEG-15 methyl ether polydimethylsiloxane, oleoyl glutamic acid, triethanolamine, menthyl lactate, β-nicotinamide mononucleotide and pyrroloquinoline quinone disodium salt to water in sequence, heating to a certain temperature, stirring evenly, to form a basic solution;

[0029] S4, fusion, slowly adding the mixed extract in step S2 to the basic solution in step S3, and continuing to stir until completely dissolved to form a uniform mixture;

[0030] S5. Cooling: cooling the mixture naturally to room temperature, filtering, filling and sealing to obtain the female antibacterial liquid.

[0031] Furthermore, in the step S4, the stirring speed is controlled at 80-120 rpm, and the stirring time is 20-30 minutes.

[0032] Furthermore, in the step S3, the heating temperature is 70-80° C., the stirring speed is controlled at 50-100 rpm, and the stirring time is 20-30 minutes to ensure that all ingredients are fully mixed.

[0033] Furthermore, in the cooling step S5, a natural cooling method is used, and the cooling time is 2-4 hours to ensure that the active ingredients in the mixture are stable and not prone to failure.

[0034] The advantages of the present invention compared with the prior art are:

[0035] 1. The present invention provides a female antibacterial liquid containing Cnidium monnieri extract and a preparation method thereof. By carefully selecting a variety of natural plant extracts (such as Sophora flavescens, Cnidium monnieri, Cinchona bark, Chrysanthemum indica, Licorice, Honeysuckle and Coptis chinensis) and optimizing their ratios, the antibacterial effect of the female antibacterial liquid can be significantly improved, the vaginal cleansing ability can be increased, and harmful bacteria can be removed. These extracts not only have good antibacterial effects, but also because they are derived from nature, they are mild and non-irritating to the vagina, suitable for use on sensitive skin, and avoid the problem of vaginal discomfort caused by chemical components;

[0036] 2. The present invention provides a female antibacterial liquid containing Cnidium monnieri extract and a preparation method thereof, which adopts advanced extraction technology, such as ethanol or water extraction, to ensure that each plant extract can retain its effective ingredients to the maximum extent during the extraction process, while meeting the purity requirement of not less than 90%. This high-purity extract not only enhances the antibacterial effect of the product, but also improves the safety and stability of the product. In addition, during the preparation process, by precisely controlling parameters such as temperature, time, and stirring speed, it is ensured that each component can be fully mixed and evenly mixed, avoiding component failure or quality degradation due to improper preparation. At the same time, by means of natural cooling, the active ingredients in the mixture are effectively protected, ensuring the final quality and efficacy of the product. DETAILED DESCRIPTION

[0037] The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with the present disclosure. Instead, they are merely examples of devices consistent with some aspects of the present disclosure as detailed in the appended claims.

[0038] The technical solutions in the embodiments of the present invention are clearly and completely described below. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0039] A female antibacterial liquid containing Cnidium monnieri extract, comprising the following raw materials in percentage by weight:

[0040] Sophora flavescens extract, 3%;

[0041] Cnidium monnieri extract, 3%;

[0042] Cinchona bark extract, 0.014%;

[0043] Wild chrysanthemum extract, 0.014%;

[0044] Licorice extract, 0.014%;

[0045] Honeysuckle flower extract, 0.014%;

[0046] Coptis chinensis extract, 0.014%;

[0047] Rosa damascena flower water, 10%;

[0048] Butanediol, 0.8%;

[0049] Bis-PEG-15 methyl ether dimethicone, 5%;

[0050] Cocoyl glutamate, 3%;

[0051] triethanolamine, 7%;

[0052] Menthol lactate, 0.00045%;

[0053] β-Nicotinamide mononucleotide, 0.01%;

[0054] Pyrroloquinoline quinone disodium salt, 0.02%;

[0055] Water, 68.09955%.

[0056] Furthermore, the method for extracting the Cnidium monnieri extract is as follows: after crushing the Cnidium monnieri raw material, using ethanol or water as a solvent, extracting at a certain temperature for a period of time, filtering and concentrating to obtain the Cnidium monnieri extract.

[0057] Furthermore, the temperature is 60-80°C, the extraction time is 2-4 hours, and the purity requirement is not less than 90%.

[0058] Furthermore, the extraction methods of the Sophora flavescens extract, the Cinchona bark extract, the Chrysanthemum indica extract, the Licorice extract, the Honeysuckle flower extract and the Coptis chinensis extract are all water extraction or ethanol extraction, and the purity of each extract is not less than 90%.

[0059] A method for preparing a female antibacterial liquid containing a Cnidium monnieri extract comprises the following steps:

[0060] S1. Extraction: extracting the raw materials of Cnidium monnieri, Sophora flavescens, Cinchona bark, Chrysanthemum indica, Licorice root, Honeysuckle flower and Coptis chinensis by water extraction or ethanol extraction, and the purity of each extract is not less than 90%;

[0061] S2, mixing, mixing the Sophora flavescens extract, the Cnidium monnieri extract, the Cinchona bark extract, the Chrysanthemum indici extract, the Licorice extract, the Honeysuckle extract and the Coptis chinensis extract in proportion to obtain a mixed extract;

[0062] S3, adding damask rose flower water, butylene glycol, bis-PEG-15 methyl ether polydimethylsiloxane, oleoyl glutamic acid, triethanolamine, menthyl lactate, β-nicotinamide mononucleotide and pyrroloquinoline quinone disodium salt to water in sequence, heating to a certain temperature, stirring evenly, to form a basic solution;

[0063] S4, fusion, slowly adding the mixed extract in step S2 to the basic solution in step S3, and continuing to stir until completely dissolved to form a uniform mixture;

[0064] S5. Cooling: The mixture is naturally cooled to room temperature, filtered, filled and sealed to obtain the female antibacterial liquid.

[0065] Furthermore, in step S3, the heating temperature is 70-80° C., the stirring speed is controlled at 50-100 rpm, and the stirring time is 20-30 minutes to ensure that all ingredients are fully mixed.

[0066] Furthermore, in step S4, the stirring speed during the fusion is controlled at 80-120 rpm, and the stirring time is 20-30 minutes.

[0067] Furthermore, in step S5, the cooling is carried out by a natural cooling method, and the cooling time is 2-4 hours to ensure that the active ingredients in the mixture are stable and not prone to failure.

[0068] In specific use,

[0069] Raw material composition:

[0070] Sophora flavescens extract, 3%;

[0071] Cnidium monnieri extract, 3%;

[0072] Cinchona bark extract, 0.014%;

[0073] Wild chrysanthemum extract, 0.014%;

[0074] Licorice extract, 0.014%;

[0075] Honeysuckle flower extract, 0.014%;

[0076] Coptis chinensis extract, 0.014%;

[0077] Rosa damascena flower water, 10%;

[0078] Butanediol, 0.8%;

[0079] Bis-PEG-15 methyl ether dimethicone, 5%;

[0080] Cocoyl glutamate, 3%;

[0081] triethanolamine, 7%;

[0082] Menthol lactate, 0.00045%;

[0083] β-Nicotinamide mononucleotide, 0.01%;

[0084] Pyrroloquinoline quinone disodium salt, 0.02%;

[0085] Water, 68.09955%.

[0086] Preparation method:

[0087] 1. Extraction

[0088] The raw material of Cnidium monnieri was crushed, ethanol was used as solvent, and the mixture was extracted at 70°C for 3 hours. The mixture was filtered and concentrated to obtain a Cnidium monnieri extract with a purity of 92%. The raw materials of Sophora flavescens, bark of Cina chinensis, Chrysanthemum indica, Licorice, Honeysuckle and Coptis chinensis were crushed, water extraction was used, the mixture was extracted at 70°C for 3 hours, the mixture was filtered and concentrated to obtain corresponding extracts. The purity of each extract was not less than 90%.

[0089] 2. Mix

[0090] According to the above proportions, the Sophora flavescens extract, the Cnidium monnieri extract, the Cinchona bark extract, the Chrysanthemum indici extract, the Licorice extract, the Honeysuckle flower extract and the Coptis chinensis extract are mixed evenly to obtain a mixed extract.

[0091] 3. Add

[0092] Add deionized water to a stirring container, and then add Damask Rosa flower water, butylene glycol, bis-PEG-15 methyl ether polydimethylsiloxane, cocoyl glutamate, triethanolamine, menthyl lactate, β-nicotinamide mononucleotide and pyrroloquinoline quinone disodium salt in sequence, heat to 75°C, control the stirring speed at 80 rpm, and stir for 25 minutes until all ingredients are completely dissolved and evenly dispersed to form a basic solution.

[0093] 4. Fusion

[0094] The mixed extract in step 2 was slowly added to the basic solution in step 3, and stirring was continued at a speed of 100 rpm for 25 minutes until it was completely dissolved and a uniform mixture was formed.

[0095] 5. Cooling

[0096] The mixture was cooled naturally to room temperature (about 25°C) for 3 hours, filtered to remove any undissolved particles, and filled into pre-sterilized containers using aseptic filling equipment, and the containers were sealed.

[0097] Product feature verification

[0098] The pH value of the final product was measured and the result was 4.2, which is in line with the natural pH value range of the female private parts. The antibacterial effect of the product was tested, and the results showed that it has a significant inhibitory effect on common bacteria (such as Escherichia coli and Staphylococcus aureus). The vaginal irritation of the product was evaluated, and the results showed that the product is mild and non-irritating to the vagina.

[0099] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0100] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

[0101] In summary, if ordinary technicians in this field are inspired by it and design structural methods and embodiments similar to the technical solution without creatively designing without departing from the purpose of the invention, they should all fall within the scope of protection of the invention.

Claims

1. A female antibacterial liquid containing Cnidium monnieri extract, characterized in that: The raw material composition includes the following weight percentages: Sophora flavescens extract, 3%; Cnidium monnieri extract, 3%; Cinchona bark extract, 0.014%; Wild chrysanthemum extract, 0.014%; Licorice extract, 0.014%; Honeysuckle flower extract, 0.014%; Coptis chinensis extract, 0.014%; Rosa damascena flower water, 10%; Butanediol, 0.8%; Bis-PEG-15 Methyl Ether Dimethicone, 5%; Cocoyl glutamate, 3%; triethanolamine, 7%; Menthol lactate, 0.00045%; β-Nicotinamide mononucleotide, 0.01%; Pyrroloquinoline quinone disodium salt, 0.02%; Water, 68.09955%.

2. The female antibacterial liquid containing Cnidium monnieri extract according to claim 1, characterized in that: The extraction method of the Cnidium monnieri extract comprises the following steps: crushing the Cnidium monnieri raw material, using ethanol or water as a solvent, extracting for a period of time at a certain temperature, filtering and concentrating to obtain the Cnidium monnieri extract.

3. The female antibacterial liquid containing Cnidium monnieri extract and its preparation method according to claim 2, characterized in that: The temperature is 60-80° C., the extraction time is 2-4 hours, and the purity requirement is not less than 90%.

4. The female antibacterial liquid containing Cnidium monnieri extract according to claim 1, characterized in that: The extraction methods of the sophora flavescens extract, the cinchona bark extract, the wild chrysanthemum extract, the liquorice extract, the honeysuckle flower extract and the coptis chinensis extract are all water extraction or ethanol extraction, and the purity of each extract is not less than 90%.

5. A method for preparing a female antibacterial liquid containing Cnidium monnieri extract, characterized in that: The following steps are involved: S1, extraction, wherein the raw materials of Cnidium monnieri, Sophora flavescens, Cina chinensis bark, Chrysanthemum indica, Licorice root, Honeysuckle flower and Coptis chinensis are respectively extracted by water extraction or ethanol extraction, and the purity of each extract is not less than 90%; S2, mixing, mixing the Sophora flavescens extract, the Cnidium monnieri extract, the Cinchona bark extract, the Chrysanthemum indici extract, the Licorice extract, the Honeysuckle extract and the Coptis chinensis extract in proportion to obtain a mixed extract; S3, adding damask rose flower water, butylene glycol, bis-PEG-15 methyl ether polydimethylsiloxane, oleoyl glutamic acid, triethanolamine, menthyl lactate, β-nicotinamide mononucleotide and pyrroloquinoline quinone disodium salt to water in sequence, heating to a certain temperature, stirring evenly, to form a basic solution; S4, fusion, slowly adding the mixed extract in step S2 to the basic solution in step S3, and continuing to stir until completely dissolved to form a uniform mixture; S5. Cooling: cooling the mixture naturally to room temperature, filtering, filling and sealing to obtain the female antibacterial liquid.

6. The method for preparing a female antibacterial liquid containing Cnidium monnieri extract according to claim 4, characterized in that: The heating temperature in the step S3 is 70-80° C., the stirring speed is controlled at 50-100 rpm, and the stirring time is 20-30 minutes to ensure that all ingredients are fully mixed.

7. The method for preparing a female antibacterial liquid containing Cnidium monnieri extract according to claim 4, characterized in that: In the step S4, the stirring speed is controlled at 80-120 rpm, and the stirring time is 20-30 minutes.

8. The method for preparing a female antibacterial liquid containing Cnidium monnieri extract according to claim 4, characterized in that: The cooling in step S5 is carried out by a natural cooling method, and the cooling time is 2-4 hours to ensure that the active ingredients in the mixture are stable and not prone to failure.