Traditional Chinese medicine compatible extract beverage for tonifying spleen and kidney and eliminating dampness, extract and preparation method

Abstract

The invention belongs to the technical field of food beverage medicine preparation, and discloses a traditional Chinese medicine compatible extract beverage for tonifying spleen and kidney and eliminating dampness, an extract and a preparation method, the composition is prepared from the following materials: 0.9 g of fried red bean water extract, 0.9 g of fried coix seed water extract and 0.2 g of fresh dendrobium huoshanense stem water extract. The traditional Chinese medicine has the effects of warming and tonifying spleen and kidney, eliminating dampness, tonifying qi and promoting salivation. According to the formula, all the raw materials have a synergistic effect, the health-care effects of warming the spleen and the kidney, dispelling cold, removing food retention, tonifying qi and promoting salivation are achieved, and the product is fresh and cool in taste, convenient to carry, capable of being directly brewed and drunk and deeply loved by young people. The traditional Chinese medicine compatible extract can be prepared into a sugar-free liquid beverage, a sugar-free solid beverage, a sweet liquid beverage and a sweet solid beverage, and is deeply loved by the majority of young people.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicine health care, and in particular relates to a Chinese medicine compatibility extract for tonifying the spleen and kidney and removing dampness, and a preparation method thereof. Background Art

[0002] The kidney is the foundation of the innate constitution and the root of the yin and yang of the internal organs. It absorbs qi, controls water, and stores essence. The yin and yang of the kidney are the foundation of the yin and yang of the whole body. The spleen is the foundation of the acquired constitution and the source of the production of qi and blood. It is responsible for transporting water and grain, transporting water, raising clearness, and regulating blood. All diseases are cured by the spleen and kidney, and the spleen and kidney are most afraid of dampness and cold. Dampness is liquid waste of human metabolism and should be discharged through urine, but modern people's habits such as air conditioning, eating cold drinks, and drinking iced drinks will aggravate dampness and coldness. Especially in summer, iced drinks are hard to refuse. Most young people drink a lot of iced drinks every summer, causing water and moisture to accumulate in body tissues and internal organs, which will lead to puffiness, hair loss, sticky stools, eczema, gynecological inflammation, etc. When cold air accumulates in the body, it will cause sore waist and knees, cold hands and feet, cold uterus, dysmenorrhea, and even infertility. Spleen and kidney dampness and coldness cause spleen and kidney yang deficiency, and its transportation and transformation function is weakened, which will lead to more dampness and coldness accumulation in the body.

[0003] The most relevant prior art is about the extraction and preparation of single Chinese herbal medicine ingredients (such as red beans, coix seeds or Huoshan dendrobium). These prior art mainly focus on how to extract and prepare active ingredients from single Chinese herbal medicines. The main technical problems of the prior art include:

[0004] 1. Lack of research on the interactions between different components of traditional Chinese medicine. The extraction and preparation of single traditional Chinese medicine components do not fully consider the synergistic effects or mutual influences between different components.

[0005] 2. Lack of optimization of specific proportions and preparation processes. The prior art has not studied and determined in detail the optimal proportions and steps of different Chinese medicine ingredients in the preparation process, which affects the effect and stability of the final product.

[0006] 3. There is a lack of specific research on the effects of Chinese herbal medicine extracts on tonifying the spleen and kidney and removing dampness. Existing technologies mainly focus on the extraction and preparation process itself, without optimizing and verifying specific health effects.

[0007] Prior art: A method for preparing a Chinese medicine solid beverage comprises the following steps:

[0008] 1. Select medicinal materials, including Ophiopogon japonicus, mulberry leaves, almonds, forsythia, chrysanthemum, wolfberry, yam, coix seed, cassia seed, dendrobium, etc., and boil them with water to extract the liquid;

[0009] 2. Concentrate to obtain a liquid medicine;

[0010] 3. Add isomaltooligosaccharide to the solution and stir evenly;

[0011] 4. The cooled medicinal liquid is spray-dried to obtain a Chinese medicine solid beverage.

[0012] Problems with existing technologies:

[0013] 1. The existing technology requires multiple steps such as decoction, concentration, addition of sugars, stirring, cooling and spray drying. The preparation process is relatively complicated and time-consuming and resource-intensive.

[0014] 2. The Chinese medicine compatibility of the existing scheme includes a variety of medicinal materials. Although it can achieve a variety of effects, it is not focused enough on symptomatic treatment. For example, in terms of tonifying the spleen and kidney and removing dampness, the effect is not as accurate as the formula listed in the above invention.

[0015] 3. The existing technology requires the addition of a large amount of sugars during the preparation process, which is not friendly to diabetic patients.

[0016] Compared with the existing technology, the above four solutions are more streamlined, requiring only extract powder and purified water, and can be directly taken or drunk, which is convenient and quick. At the same time, according to personal taste and needs, you can choose to add rock sugar or honey, which is more humane. Summary of the invention

[0017] In view of the above problems, the present invention provides a Chinese medicine compatibility extract for tonifying the spleen and kidney and removing dampness, which has the effects of warming and tonifying the spleen and kidney, removing dampness, and invigorating qi and promoting body fluid. In addition, the components of the Chinese medicine compatibility extract for tonifying the spleen and kidney and removing dampness of the present invention are all medicine and food, and the safety is extremely high. Therefore, the Chinese medicine compatibility extract of the present invention can be prepared into a delicious beverage, which can not only meet people's demand for iced beverages, but also achieve the effect of removing dampness.

[0018] To achieve the above purpose, the technical solution adopted by the present invention is: a solid drink of Chinese medicine compatibility extract for tonifying spleen and kidney and removing dampness, which contains 0.9g of stir-fried red bean extract powder, 0.9g of stir-fried coix seed extract powder, and 0.2g of fresh Huoshan dendrobium stem extract powder by mass. Drinking method: Take it with 100-500mL of pure water.

[0019] Another object of the present invention is to provide a solid drink of Chinese medicine compatibility extracts for tonifying spleen and kidney and removing dampness, which is composed of the following components by mass: 0.9g of stir-fried red bean extract powder, 0.9g of stir-fried coix seed extract powder, 0.2g of fresh Huoshan dendrobium stem extract powder, and 25g of crystal sugar. Drinking method: Take it with 500mL of pure water.

[0020] Another object of the present invention is to provide a liquid beverage of Chinese herbal medicine compatibility extract for tonifying spleen and kidney and removing dampness, which is composed of the following components by mass: 0.9g of stir-fried red bean extract powder, 0.9g of stir-fried coix seed extract powder, 0.2g of fresh Huoshan dendrobium stem extract powder, and 500mL of purified water. Drinking method: It can be drunk directly.

[0021] Another object of the present invention is to provide a Chinese medicine compatibility extract liquid drink for tonifying spleen and kidney and removing dampness, which is composed of the following components by mass: 0.9g of stir-fried red bean extract powder, 0.9g of stir-fried coix seed extract powder, 0.2g of fresh Huoshan dendrobium stem extract powder, 10g of honey, and 500mL of purified water. Drinking method: It can be drunk directly.

[0022] Another object of the present invention is to provide a Chinese medicine compatibility extract for tonifying the spleen and kidney and removing dampness, which is composed of the following components by mass: stir-fried red bean extract powder: stir-fried coix seed extract powder: fresh Huoshan dendrobium stem extract powder = 9:9:2.

[0023] In order to clarify whether the Chinese medicine compatibility extract of the present invention has the effect of removing dampness, the present invention conducts drug efficacy research in animal experiments and human clinical experiments respectively. The present invention adopts the cold and damp environment + cold diet + high-fat feed composite factor method to establish a rat model of cold and dampness obstructing spleen syndrome, and studies the dampness removing effect of the Chinese medicine compatibility extract of the present invention on this model. It was found that the rats with cold and dampness obstructing spleen syndrome had symptoms of heavy dampness, which were mainly manifested as: mental depression, slow reaction, slow movement, lazy movement, arched back, squinting and gathering, lying quietly, thin body, loose hair, yellow and dull, reduced food intake, dirty anus, loose stools, reduced urine D-xylose excretion rate, increased motilin, and reduced gastrin. The Chinese medicine compatibility extract can effectively remove dampness, which is mainly manifested as: after rats were gavaged with the Chinese medicine compatibility extract, the appearance and morphology were improved to varying degrees, and the urine D-xylose excretion rate and gastrin level were increased, and the motilin level was reduced. The present invention recruits volunteers with heavy dampness to study the Chinese herbal medicine compatibility extract of the present invention at the clinical level. The results show that the Chinese herbal medicine compatibility extract of the present invention can effectively reduce the heavy dampness of the volunteers. The present invention also finds that healthy volunteers who drink iced beverages prepared from the Chinese herbal medicine compatibility extract of the present invention for a long time will not cause heavy dampness. These results show that the Chinese herbal medicine compatibility extract of the present invention can not only be prepared into medicines or food and beverages with the function of removing dampness, but also can be prepared into beverages that will not cause heavy dampness after being chilled, and can be matched with sweeteners such as honey, white sugar or fructose syrup, and has a good taste, which is very popular among young people.

[0024] Preparation of stir-fried red bean extract: Place dry red beans in an iron pan at 300-400°C and stir-fry for 8-10 minutes. After frying, boil and reflux for 2 hours at a ratio of stir-fried red beans to distilled water of 1:10, collect the liquid, and filter it with a 200-mesh filter cloth to obtain a stir-fried red bean initial extract. Use a rotary evaporator to concentrate the stir-fried red bean initial extract to obtain a stir-fried red bean concentrated extract, and further use a freeze dryer to freeze-dry the stir-fried red bean concentrated extract into powder to obtain a stir-fried red bean extract powder. The stir-fried red bean extract prepared by the preparation method has the following advantages: ① After the red beans are stir-fried by the stir-frying method of the present invention, the dehumidifying effect is more obvious, and it has the effects of promoting body fluid and quenching thirst, reducing swelling and relieving pain, strengthening the spleen and stomach, and calming the nerves; ② After the red beans are stir-fried by the stir-frying method of the present invention, the bean smell of the red beans will be removed, and the taste of the prepared extract is better; ③ The stir-fried red bean extract obtained by the extraction method of the present invention has good water solubility, which is convenient for preparing the stir-fried red bean extract of the present invention into a solid or liquid dosage form product.

[0025] Preparation of stir-fried coix seed extract: Place the coix seed in an iron pan at 300-400°C and stir-fry for 8-10 minutes. After frying, boil and reflux for 2 hours in a ratio of stir-fried coix seed: distilled water = 1:10, collect the liquid, and filter it with a 200-mesh filter cloth to obtain the initial extract of stir-fried coix seed. Use a rotary evaporator to concentrate the initial extract of stir-fried coix seed to obtain a concentrated extract of stir-fried coix seed, and further use a freeze dryer to freeze-dry the concentrated extract of stir-fried coix seed into powder to obtain stir-fried coix seed extract powder. The stir-fried coix seed extract prepared by this preparation method has the following advantages: ① Coix seed is a cold Chinese medicine. After being stir-fried by the stir-frying method of the present invention, the medicinal property of the coix seed becomes mild and it does not belong to the cold medicine. The medicinal effect is enhanced and it has good spleen-strengthening and diuretic and dampness-removing effects; ② After the coix seed is stir-fried by the stir-frying method of the present invention, the taste of the extract prepared is better; ③ The stir-fried coix seed extract obtained by the extraction method of the present invention has good water solubility, which is convenient for preparing the stir-fried coix seed extract of the present invention into a commercial product in the form of solid or liquid dosage forms.

[0026] Preparation of fresh Huoshan Dendrobium stem extract: Pick 3-5 years old fresh Huoshan Dendrobium stems, wash them with clean water, boil and reflux for 2 hours according to the ratio of fresh Huoshan Dendrobium stem: distilled water = 1:10, collect the liquid, and filter it with a 200-mesh filter cloth to obtain the initial extract of fresh Huoshan Dendrobium stem. Use a rotary evaporator to concentrate the initial extract of fresh Huoshan Dendrobium stem to obtain a concentrated extract of fresh Huoshan Dendrobium stem, and further use a freeze dryer to freeze-dry the concentrated extract of fresh Huoshan Dendrobium stem into powder to obtain fresh Huoshan Dendrobium stem extract powder. The fresh Huoshan Dendrobium stem extract prepared by this preparation method has the following advantages: ① The extract prepared from the fresh Huoshan Dendrobium stem by the extraction method of the present invention removes the grassy taste of the fresh Huoshan Dendrobium, and the taste becomes better; ② The fresh Huoshan Dendrobium stem extract obtained by the extraction method of the present invention has good water solubility, which is convenient for preparing the fresh Huoshan Dendrobium stem extract of the present invention into a commercial product in solid or liquid dosage forms.

[0027] Red beans are mild in nature, neither cold nor hot, and have a series of effects such as dispelling wind and clearing heat, drying dampness and relieving itching, moisturizing and nourishing the skin, and tonifying the spleen. After being fried, the dampness-removing effect of red beans is more obvious, and it has the effects of promoting fluid and quenching thirst, reducing swelling and relieving pain, strengthening the spleen and stomach, and calming the nerves. In addition, frying will remove the beany smell of red beans, and the taste of the extract prepared is better. Coix is ​​a cold Chinese medicine, which has the effects of promoting water and penetrating dampness, strengthening the spleen and stopping diarrhea, removing numbness, draining pus, detoxifying and dispersing knots. After being fried, coix has a mild nature and does not belong to cold medicines. The efficacy is enhanced, and it has a good spleen-strengthening and diuretic effects, and the taste becomes better. Huoshan Dendrobium is slightly cold in nature, and has the effects of clearing the liver and improving eyesight, benefiting the stomach and producing fluid, nourishing yin and clearing heat. The three medicines are used together, and the medicinal properties are mild, playing the role of warming the spleen and kidney, dispersing cold and eliminating accumulation, invigorating qi and promoting fluid, and tonifying the kidney and removing dampness.

[0028] In combination with the above technical solutions and the technical problems solved, the advantages and positive effects of the technical solutions to be protected by the present invention are as follows:

[0029] First, the raw materials of the formula of the present invention work synergistically and have the health care effects of warming the spleen and kidney, dispelling cold and eliminating accumulation, invigorating qi and promoting body fluid production. The product has a refreshing taste, is easy to carry, and can be directly brewed and drunk, and is deeply loved by young people.

[0030] The Chinese herbal medicine compatibility extract of the present invention can be prepared into sugar-free liquid beverages, sugar-free solid beverages, sweet liquid beverages and sweet solid beverages, which are deeply loved by young people. In addition, the Chinese herbal medicine compatibility extract of the present invention has two characteristics when prepared into beverages. First, it has a dampness-removing effect, and second, it does not cause heavy moisture after being chilled, which is very popular for young people who love chilled beverages in summer.

[0031] Secondly, the present invention is composed of stir-fried red bean extract powder, stir-fried coix seed extract powder and fresh Huoshan dendrobium stem extract powder, and the technological progress brought about is providing a new and effective combination for tonifying the spleen and kidney and removing dampness.

[0032] The specific preparation method of the stir-fried red bean extract of the present invention brings about a technical advancement in that the process of extracting the effective components of the red bean is optimized to ensure the medicinal efficacy thereof.

[0033] The process of freeze-drying the roasted red bean concentrated extract into powder brings about a technical advancement in that an effective method is provided to convert the liquid extract into a powder form that is convenient for storage and use.

[0034] The specific preparation method of the stir-fried coix seed extract of the present invention brings about a technical advancement in that the process of extracting the effective components of coix seed is optimized to ensure the medicinal efficacy thereof.

[0035] The process of freeze-drying the stir-fried coix seed concentrated extract into powder brings about a technical advancement in that an effective method is provided to convert the liquid extract into a powder form that is convenient for storage and use.

[0036] The technical progress brought by the present invention is to optimize the process of extracting the effective components of the stems of Dendrobium huoshanense to ensure the medicinal efficacy thereof, and also to provide an effective method for converting the liquid extract into a powder form that is convenient for storage and use.

[0037] The invention provides a new and effective Chinese medicine compatibility extract formula, and optimizes the process of extracting each Chinese medicine component and converting the liquid extract into powder form. BRIEF DESCRIPTION OF THE DRAWINGS

[0038] Figure 1 The invention discloses a method for preparing a stir-fried red bean extract capable of tonifying the spleen and kidney and removing dampness provided by an embodiment of the invention.

[0039] Figure 2 The invention discloses a method for preparing a stir-fried coix seed extract for tonifying the spleen and kidney and removing dampness provided by an embodiment of the invention.

[0040] Figure 3 The invention discloses a method for preparing a fresh stem extract of Dendrobium huoshanense for invigorating the spleen and kidney and removing dampness provided by an embodiment of the invention. DETAILED DESCRIPTION

[0041] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0042] The Chinese medicine compatibility extract for invigorating spleen and kidney and removing dampness provided by the invention consists of the following components by mass: stir-fried red bean extract powder: stir-fried coix seed extract powder: fresh Huoshan dendrobium stem extract powder = 9:9:2.

[0043] like Figure 1 As shown, the preparation method of the stir-fried red bean extract is as follows: dry red beans are placed in an iron pan at 300-400°C and stir-fried for 8-10 minutes. After the stir-frying is completed, the stir-fried red beans: distilled water = 1:10 ratio, after boiling and refluxing for 2 hours, the liquid is collected and filtered with a 200-mesh filter cloth to obtain the stir-fried red bean initial extract. The stir-fried red bean initial extract is concentrated using a rotary evaporator to obtain a stir-fried red bean concentrated extract, and further, the stir-fried red bean concentrated extract is freeze-dried into powder using a freeze dryer to obtain a stir-fried red bean extract powder.

[0044] The method for preparing the fried red bean extract comprises the following steps: the temperature for frying the red bean is 300-400 DEG C, and the frying time is 8-10 minutes.

[0045] like Figure 2 As shown, the preparation method of the stir-fried coix seed extract is as follows: the coix seed is placed in an iron pan at 300-400°C and stir-fried for 8-10 minutes. After the stir-frying is completed, the solution is boiled and refluxed for 2 hours according to the ratio of stir-fried coix seed: distilled water = 1:10, and then the solution is collected and filtered using a 200-mesh filter cloth to obtain the initial extract of stir-fried coix seed. The initial extract of stir-fried coix seed is concentrated using a rotary evaporator to obtain a concentrated extract of stir-fried coix seed, and further, the concentrated extract of stir-fried coix seed is freeze-dried into powder using a freeze dryer to obtain a stir-fried coix seed extract powder.

[0046] The temperature for frying coix seeds is 300-400°C, and the frying time is 8-10 minutes.

[0047] like Figure 3 As shown, the preparation method of fresh Huoshan Dendrobium stem extract is as follows: the fresh Huoshan Dendrobium stem is cleaned, and after boiling and refluxing for 2 hours according to the ratio of fresh Huoshan Dendrobium stem: distilled water = 1:10, the liquid is collected, and filtered with a 200-mesh filter cloth to obtain the initial extract of fresh Huoshan Dendrobium stem. The initial extract of fresh Huoshan Dendrobium stem is concentrated by using a rotary evaporator to obtain a concentrated extract of fresh Huoshan Dendrobium stem, and further, the concentrated extract of fresh Huoshan Dendrobium stem is freeze-dried into powder by using a freeze dryer to obtain a fresh Huoshan Dendrobium stem extract powder. The present invention uses 3 to 5 years old fresh Huoshan Dendrobium stems.

[0048] The invention discloses an application of the pharmaceutical composition in preparing a drug for removing dampness.

[0049] The invention discloses an application of the pharmaceutical composition in preparing a solid beverage for removing dampness.

[0050] The pharmaceutical composition provided by the present invention is used for preparing a solid drink, and the solid drink has a dampness-removing effect.

[0051] The solid beverage preparation provided by the present invention does not cause the problem of heavy moisture when the solid beverage is drunk after being chilled for a long time. The Chinese medicine compatibility extract of the present invention can be used together with other sweeteners such as rock sugar and honey to prepare a sweet solid beverage, and has the effect of removing moisture. The sweet solid beverage drunk after being chilled for a long time does not cause the problem of heavy moisture.

[0052] The application of the pharmaceutical composition provided by the present invention in preparing a liquid beverage for removing dampness. The Chinese herbal medicine compatibility extract of the present invention can be directly mixed with pure water in a mass ratio of 2 to 5:500 to prepare a liquid beverage, and has a dampness-removing effect. Long-term drinking of the liquid beverage of claim 15 after being chilled will not cause the problem of heavy dampness. Sweeteners such as rock sugar or honey can be added to the liquid beverage in a mass ratio of no more than 5% to prepare a sweet liquid beverage, and have a dampness-removing effect.

[0053] The pharmaceutical composition provided by the present invention can be used for preparing sweet liquid beverages, and long-term drinking of the sweet liquid beverage after ice-cold drinking will not cause the problem of heavy moisture. Application of the pharmaceutical composition in preparing liquid beverages for diabetic patients. Application of the pharmaceutical composition in preparing solid beverages for diabetic patients.

[0054] Example 1

[0055] Preparation of stir-fried red bean extract: Place dry red beans in an iron pan at 300-400°C and stir-fry for 8-10 minutes. After frying, boil and reflux for 2 hours at a ratio of stir-fried red beans to distilled water of 1:10, collect the liquid, and filter it with a 200-mesh filter cloth to obtain a stir-fried red bean initial extract. Use a rotary evaporator to concentrate the stir-fried red bean initial extract to obtain a stir-fried red bean concentrated extract, and further use a freeze dryer to freeze-dry the stir-fried red bean concentrated extract into powder to obtain a stir-fried red bean extract powder.

[0056] Example 2

[0057] Preparation of stir-fried coix seed extract: Place the coix seed in an iron pan at 300-400°C and stir-fry for 8-10 minutes. After frying, boil and reflux for 2 hours in a ratio of stir-fried coix seed: distilled water = 1:10, collect the liquid, and filter it with a 200-mesh filter cloth to obtain the initial extract of stir-fried coix seed. Use a rotary evaporator to concentrate the initial extract of stir-fried coix seed to obtain a concentrated extract of stir-fried coix seed, and further use a freeze dryer to freeze-dry the concentrated extract of stir-fried coix seed into powder to obtain stir-fried coix seed extract powder.

[0058] Example 3

[0059] Preparation of fresh Huoshan Dendrobium stem extract: Pick 3-5 years old fresh Huoshan Dendrobium stems, wash them with clean water, boil and reflux for 2 hours according to the ratio of fresh Huoshan Dendrobium stem: distilled water = 1:10, collect the liquid, and filter it with a 200-mesh filter cloth to obtain the initial extract of fresh Huoshan Dendrobium stem. Use a rotary evaporator to concentrate the initial extract of fresh Huoshan Dendrobium stem to obtain a concentrated extract of fresh Huoshan Dendrobium stem, and further use a freeze dryer to freeze-dry the concentrated extract of fresh Huoshan Dendrobium stem into powder to obtain fresh Huoshan Dendrobium stem extract powder.

[0060] Example 4

[0061] A Chinese medicinal compatibility extract for tonifying the spleen and kidney and removing dampness, comprising the following components in a mass ratio: stir-fried red bean extract powder: stir-fried coix seed extract powder: fresh Huoshan dendrobium stem extract powder = 9:9:2.

[0062] Example 5

[0063] A solid drink of Chinese herbal medicine extracts for tonifying spleen and kidney and removing dampness, comprising the following components by mass: 0.9g of stir-fried red bean extract powder, 0.9g of stir-fried coix seed extract powder, and 0.2g of fresh Huoshan dendrobium stem extract powder. Drinking method: Take with 100-500mL of pure water.

[0064] Example 6

[0065] A Chinese medicine compatibility extract solid drink for tonifying spleen and kidney and removing dampness, composed of the following components by mass: 0.9g of stir-fried red bean extract powder, 0.9g of stir-fried coix seed extract powder, 0.2g of fresh Huoshan dendrobium stem extract powder, and 25g of crystal sugar. Drinking method: Take it with 500mL of pure water.

[0066] Example 7

[0067] A liquid beverage of Chinese herbal medicine extract for tonifying spleen and kidney and removing dampness, composed of the following components by mass: 0.9g of stir-fried red bean extract powder, 0.9g of stir-fried coix seed extract powder, 0.2g of fresh Huoshan dendrobium stem extract powder, and 500mL of purified water. Drinking method: can be drunk directly.

[0068] Example 8

[0069] A liquid beverage of Chinese herbal medicine extract for tonifying spleen and kidney and removing dampness, composed of the following components by mass: 0.9g of stir-fried red bean extract powder, 0.9g of stir-fried coix seed extract powder, 0.2g of fresh Huoshan dendrobium stem extract powder, 10g of honey, and 500mL of purified water. Drinking method: can be drunk directly.

[0070] The above-mentioned embodiments only express the specific implementation of the present invention, and the description thereof is relatively specific and detailed, but it cannot be understood as limiting the scope of the present invention. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, which all belong to the protection scope of the present invention.

[0071] Effect Study 1

[0072] The present invention adopts the cold and damp environment + cold diet + high-fat feed composite factor method to establish a rat model of cold and dampness obstructing spleen syndrome, and studies the dehumidifying effect of the Chinese medicine compatibility extract of the present invention on this model. The rat model of cold and dampness obstructing spleen syndrome is specifically constructed as follows: the rat is placed in a cold and damp environment mouse cage, 1.5h / time, once in the morning and afternoon, and the interval between the two cold and damp stimulations is 4h; every night each rat is fed with 50% cooked flour paste at about 8°C, the dosage is 15ml / k; and it is fed with high-fat feed every day, and the modeling time is 3 weeks. Cold and damp environment mouse cage production method: the mouse cage size is 50cm×40cm×40cm, the bottom is provided with a drainage control hole, a mesh partition is placed 5cm away from the bottom of the mouse cage, and a small overflow hole is provided 2cm away from the partition; the top of the mouse cage is a switchable cover, and a hole with a diameter of 3cm is opened on the upper part for ventilation. During the experiment, water at about 5°C was put into the mouse cage (the water was changed every 30 minutes or so), and the liquid level reached the overflow hole. The mouse was placed on the mesh partition in the mouse cage, and the immersion depth was about 2 cm.

[0073] Thirty 2-month-old Wistar rats were randomly divided into a normal group, a cold-dampness-spleen syndrome group, and a Chinese medicine compatibility extract treatment group. The rats in the normal group were not treated. After 3 weeks of normal feeding, they were gavaged with 1 mL of distilled water every day and continued to be fed normally for 2 weeks. Rats in the cold-dampness-spleen syndrome group: After 3 weeks of cold-dampness-spleen syndrome modeling, 1 mL of distilled water was gavaged every day, and the cold-dampness-spleen syndrome modeling was continued for 2 weeks. Chinese medicine compatibility extract treatment group: After 3 weeks of cold-dampness-spleen syndrome modeling, 50 mg / kg of the Chinese medicine compatibility extract described in Example 4 was gavaged every day, and the cold-dampness-spleen syndrome modeling was continued for 2 weeks. During the modeling period, the general morphological manifestations of rats in each group were observed throughout the whole process, including spirit, hair, activity, urination and defecation conditions, etc. After the experiment, urine and serum of rats in each group were collected, and the urine D-xylose excretion rate was detected using a kit, and the motilin and gastrin in serum were detected using a kit.

[0074] The results showed that during the modeling and drug counter-evidence period, the rats in the normal group were in good mental state, agile, responsive, dense and shiny hair, strong muscles, good food intake, and dry and granular stools. The rats in the cold-dampness spleen syndrome group were listless, slow to react, slow to move, lazy, arched back, squinting and gathering, lying quietly, thin, with loose, yellow and dull hair, reduced food intake, dirty anus, and loose stools. After the rats in the Chinese herbal compatibility extract treatment group were gavaged with the Chinese herbal compatibility extract, their appearance and morphology improved to varying degrees. The test results of the kit are shown in Table 1. Compared with the normal group, the urinary D-xylose excretion rate of the rats in the cold-dampness spleen syndrome group was reduced, motilin was increased, and gastrin was reduced, and these changes were significantly reversed after treatment with the Chinese herbal compatibility extract.

[0075] Table 1 Changes in urinary D-xylose excretion rate, motilin and gastrin in rats of each group after intervention with the Chinese medicine compatibility extract of the present invention

[0076]

[0077] Note: Compared with the normal group, # P<0.05, ## P<0.01; compared with the group with cold-dampness obstructing spleen syndrome, * P<0.05, ** P<0.01.

[0078] Conclusion: This result shows that, at the animal experimental level, the Chinese herbal medicine combination extract described in Example 4 has the effect of treating cold-dampness obstructing the spleen syndrome and is effective.

[0079] Effect Study 2

[0080] Data and methods: Ten patients with high humidity were collected, including 5 males and 5 females, aged 20-60 years old.

[0081] Method of administration: Volunteers drink 1 to 3 servings of the solid beverage of the Chinese herbal extract described in Example 5 every day for 2 consecutive weeks.

[0082] Results: Before the volunteers drank the solid drink of the Chinese herbal extract described in Example 5, Associate Professor Liu Ying and Associate Professor Hao Qing of the School of Integrated Chinese and Western Medicine of Binzhou Medical College conducted a TCM diagnosis. The diagnosis results showed that all volunteers had soft and slippery pulses and yellow and greasy tongue coating. After the volunteers drank the solid drink of the Chinese herbal extract described in Example 5 every day for 2 weeks, the above symptoms of dampness were significantly alleviated.

[0083] Conclusion: This result shows that the solid beverage of the Chinese herbal medicine extract described in Example 5 has the effect of removing dampness.

[0084] Effect Study 3

[0085] Data and methods: Ten patients with high humidity were collected, including 5 males and 5 females, aged 20-60 years old.

[0086] Method of administration: Volunteers drink 1 to 3 servings of the solid beverage of the Chinese herbal medicine extract described in Example 6 every day for 2 consecutive weeks.

[0087] Results: Before the volunteers drank the solid drink of the Chinese herbal extract described in Example 6, Associate Professor Liu Ying and Associate Professor Hao Qing of the School of Integrated Chinese and Western Medicine of Binzhou Medical College conducted a TCM diagnosis. The diagnosis results showed that all volunteers had soft and slippery pulses and yellow and greasy tongue coating. After the volunteers drank the solid drink of the Chinese herbal extract described in Example 6 every day for 2 weeks, the above symptoms of dampness were significantly alleviated.

[0088] Conclusion: This result shows that the solid beverage of the Chinese herbal medicine extract described in Example 6 has the effect of removing dampness.

[0089] Effect Study 4

[0090] Data and methods: Ten patients with high humidity were collected, including 5 males and 5 females, aged 20-60 years old.

[0091] Method of administration: Volunteers drink 1 to 3 servings of the Chinese herbal extract liquid beverage described in Example 7 every day for 2 consecutive weeks.

[0092] Results: Before the volunteers drank the liquid drink of the Chinese herbal extract described in Example 7, Associate Professor Liu Ying and Associate Professor Hao Qing of the School of Integrated Chinese and Western Medicine of Binzhou Medical College conducted a TCM diagnosis. The diagnosis results showed that all volunteers had soft and slippery pulses and yellow and greasy tongue coating. After the volunteers drank the liquid drink of the Chinese herbal extract described in Example 7 every day for 2 weeks, the above symptoms of dampness were significantly alleviated.

[0093] Conclusion: This result shows that the Chinese herbal medicine extract liquid drink described in Example 7 has the effect of removing dampness.

[0094] Effect Study 5

[0095] Data and methods: Ten patients with high humidity were collected, including 5 males and 5 females, aged 20-60 years old.

[0096] Method of administration: Volunteers drink 1 to 3 servings of the Chinese herbal extract liquid beverage described in Example 8 every day for 2 consecutive weeks.

[0097] Results: Before the volunteers drank the liquid drink of the Chinese herbal extract described in Example 8, Associate Professor Liu Ying and Associate Professor Hao Qing of the School of Integrated Chinese and Western Medicine of Binzhou Medical College conducted a TCM diagnosis. The diagnosis results showed that all volunteers had soft and slippery pulses and yellow and greasy tongue coating. After the volunteers drank the liquid drink of the Chinese herbal extract described in Example 8 every day for 2 weeks, the above symptoms of dampness were significantly alleviated.

[0098] Conclusion: This result shows that the Chinese herbal medicine extract liquid drink described in Example 8 has the effect of removing dampness.

[0099] Effect Study 6

[0100] Data and methods: Ten healthy volunteers were collected, including 5 males and 5 females, aged 20-60 years old.

[0101] Method of administration: Volunteers drink 1 to 3 servings of the iced solid beverage of the Chinese herbal extract described in Example 5 every day for 2 consecutive weeks.

[0102] Results: After the volunteers drank the iced solid beverage of the Chinese herbal medicine extract described in Example 5, the volunteers did not experience increased dampness.

[0103] Conclusion: This result shows that the solid drink of the Chinese herbal medicine extract described in Example 5 will not cause the dampness to increase.

[0104] Effect Study 7

[0105] Data and methods: Ten healthy volunteers were collected, including 5 males and 5 females, aged 20-60 years old.

[0106] Method of administration: Volunteers drink 1 to 3 servings of the iced solid beverage of the Chinese herbal extract described in Example 6 every day for 2 consecutive weeks.

[0107] Results: After the volunteers drank the iced solid beverage of the Chinese herbal medicine extract described in Example 6, the volunteers did not experience increased dampness.

[0108] Conclusion: This result shows that the solid drink of the Chinese herbal medicine extract described in Example 6 will not cause the dampness to increase.

[0109] Effect study 8

[0110] Data and methods: Ten healthy volunteers were collected, including 5 males and 5 females, aged 20-60 years old.

[0111] Method of administration: Volunteers drink 1 to 3 servings of the chilled Chinese medicine extract liquid beverage described in Example 7 every day for 2 consecutive weeks.

[0112] Results: After the volunteers drank the iced liquid beverage of the Chinese herbal medicine extract described in Example 7, the volunteers did not experience increased dampness.

[0113] Conclusion: This result shows that the Chinese herbal extract liquid drink described in Example 7 will not cause increased dampness.

[0114] Effect Study 9

[0115] Data and methods: Ten healthy volunteers were collected, including 5 males and 5 females, aged 20-60 years old.

[0116] Method of administration: Volunteers drink 1 to 3 servings of the chilled Chinese medicine extract liquid beverage described in Example 8 every day for 2 consecutive weeks.

[0117] Results: After the volunteers drank the iced liquid beverage of the Chinese herbal extract described in Example 8, the volunteers did not experience increased dampness.

[0118] Conclusion: This result shows that the Chinese herbal medicine extract liquid drink described in Example 8 will not cause increased dampness.

[0119] Effect Study 9

[0120] Typical Cases

[0121] Zhang, male, 26 years old, from Linyi City, Shandong Province, was diagnosed by traditional Chinese medicine as having heavy dampness, puffy weight, and eczema. When participating in this clinical study volunteer, after drinking the solid beverage of the Chinese medicine compatibility extract described in Example 5 for 2 weeks, the situation of heavy dampness was significantly improved, and the weight decreased, and the eczema was also alleviated. Subsequently, Zhang continued to drink the Chinese medicine compatibility extract of the present invention for more than 20 days, and the eczema was cured. This result shows that the Chinese medicine compatibility extract beverage of the present invention has a good trend effect and also has a certain weight loss effect.

[0122] Guo, female, 24 years old, from Yanggu County, Liaocheng, Shandong Province, was diagnosed by traditional Chinese medicine as heavy dampness, and had symptoms of indigestion, abdominal distension and loss of appetite. When participating in this clinical study volunteer, after drinking the solid drink of Chinese medicine compatibility extract described in Example 5 for 2 weeks, the situation of heavy dampness was significantly improved, and the situation of indigestion, abdominal distension and loss of appetite was also improved. This result shows that the Chinese medicine compatibility extract drink of the present invention has a good trend effect.

[0123] Zheng, male, 56 years old, from Shouguang, Shandong, was diagnosed by traditional Chinese medicine as having heavy dampness and diabetes. When participating in this clinical study, the volunteers drank the solid beverage of the Chinese herbal compatibility extract described in Example 5 for 2 weeks, and the heavy dampness was significantly improved, and there was no disorder in blood sugar during the period of drinking the Chinese herbal compatibility extract beverage of the present invention. This result shows that the Chinese herbal compatibility extract beverage of the present invention is suitable for diabetic patients.

[0124] The above description is only a specific implementation mode of the present invention, but the protection scope of the present invention is not limited thereto. Any modifications, equivalent substitutions and improvements made by any technician familiar with the technical field within the technical scope disclosed by the present invention and within the spirit and principle of the present invention should be covered by the protection scope of the present invention.

Claims

1. A solid beverage of Chinese herbal medicine extracts for tonifying the spleen and kidney and removing dampness, characterized in that: By mass, there are 0.9g of fried red bean extract powder, 0.9g of fried coix seed extract powder, and 0.2g of fresh Huoshan dendrobium stem extract powder. Directions for drinking: Take with 100-500mL of pure water.

2. A solid beverage of Chinese herbal medicine extracts for tonifying the spleen and kidney and removing dampness, characterized in that: By mass, it is composed of the following components: 0.9g of fried red bean extract powder, 0.9g of fried coix seed extract powder, 0.2g of fresh Huoshan Dendrobium stem extract powder, and 25g of crystal sugar. How to drink: Take it with 500mL of pure water.

3. A liquid beverage containing Chinese herbal extracts for nourishing the spleen and kidney and removing dampness, characterized in that: By mass, it is composed of the following components: 0.9g of fried red bean extract powder, 0.9g of fried coix seed extract powder, 0.2g of fresh Huoshan Dendrobium stem extract powder, and 500mL of purified water. Drinking method: It can be drunk directly.

4. A liquid beverage of Chinese herbal medicine extract for tonifying spleen and kidney and removing dampness, characterized in that: By mass, it is composed of the following components: 0.9g of fried red bean extract powder, 0.9g of fried coix seed extract powder, 0.2g of fresh Huoshan Dendrobium stem extract powder, 10g of honey, and 500mL of purified water. Drinking method: It can be drunk directly.

5. A Chinese herbal medicine compatibility extract for tonifying the spleen and kidney and removing dampness according to any one of claims 1 to 4, characterized in that: The invention is composed of the following components by mass: stir-fried red bean extract powder: stir-fried coix seed extract powder: fresh Huoshan dendrobium stem extract powder = 9:9:

2.

6. The Chinese herbal medicine compatibility extract for tonifying the spleen and kidney and removing dampness according to claim 5, characterized in that: Preparation of stir-fried red bean extract: placing dry red beans in an iron pan at 300-400° C. and stir-frying for 8-10 minutes; after the stir-frying is completed, boiling and refluxing for 2 hours in a ratio of stir-fried red beans to distilled water = 1:10, collecting the liquid, and filtering it with a 200-mesh filter cloth to obtain a stir-fried red bean initial extract; The initial extract of the roasted red beans is concentrated by using a rotary evaporator to obtain a concentrated extract of the roasted red beans; The roasted red bean concentrated extract is freeze-dried into powder using a freeze dryer to obtain roasted red bean extract powder; the temperature of the roasted red beans is 300-400° C., and the roasting time is 8-10 minutes.

7. The Chinese herbal medicine extract for tonifying the spleen and kidney and removing dampness according to claim 6, characterized in that: Preparation of stir-fried coix seed extract: placing the coix seed in an iron pan at 300-400° C. and stir-frying for 8-10 minutes; after the stir-frying is completed, boiling and refluxing for 2 hours in a ratio of stir-fried coix seed to distilled water = 1:10, collecting the liquid, and filtering it with a 200-mesh filter cloth to obtain the initial extract of stir-fried coix seed; The initial extract of the roasted coix seeds is concentrated by using a rotary evaporator to obtain a concentrated extract of the roasted coix seeds; the concentrated extract of the roasted coix seeds is freeze-dried into powder by using a freeze dryer to obtain a roasted coix seeds extract powder; The temperature for frying coix seeds is 300-400°C, and the frying time is 8-10 minutes.

8. The Chinese herbal medicine compatibility extract for tonifying the spleen and kidney and removing dampness according to claim 1, characterized in that: Preparation of fresh Huoshan Dendrobium stem extract: clean the fresh Huoshan Dendrobium stem, boil and reflux for 2 hours according to the ratio of fresh Huoshan Dendrobium stem: distilled water = 1:10, collect the liquid, and filter it with a 200-mesh filter cloth to obtain the initial extract of fresh Huoshan Dendrobium stem; The initial extract of fresh stems of Dendrobium huoshanense was concentrated by using a rotary evaporator to obtain a concentrated extract of fresh stems of Dendrobium huoshanense. The concentrated extract of fresh stems of Dendrobium huoshanense was freeze-dried into powder by using a freeze dryer to obtain a fresh stem extract powder of Dendrobium huoshanense.

9. The preparation method of the fresh stem extract of Dendrobium huoshanense according to claim 6, characterized in that: Use 3 to 5 year old fresh stems of Dendrobium huoshanense.

10. Use of the pharmaceutical composition according to claim 1 in preparing a drug for removing dampness.

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