Microemulsion additive suitable for compounding fine glufosinate-ammonium with haloxyfop-R-methyl

Abstract

The invention discloses a microemulsion auxiliary agent suitable for compounding fine glufosinate ammonium with haloxyfop-R-methyl. The auxiliary agent comprises the following effective components: 10%-25% of styrylphenol polyoxyethylene ether, 60%-75% of alkyl glycoside, 10%-20% of fatty alcohol polyoxyethylene ether sodium sulfate and 1%-10% of ethylene glycol. A preparation prepared from the auxiliary agent can increase the infiltration capacity of the preparation, improve the pesticide effect and reduce the production cost of the preparation, and the pesticide preparation is good in cold and hot storage stability and also can improve the safety of the product to the environment.

Description

Technical Field

[0001] The invention belongs to the technical field of pesticides, and in particular relates to an adjuvant suitable for a microemulsion compounded with refined glufosinate-ammonium and high-efficiency haloxyfop-butyl. Background Art

[0002] Glufosinate-ammonium (molecular formula C 5 H 12 NO 4 P), with a molecular weight of 181.13, is an isomer of glufosinate ammonium, and is more active than traditional glufosinate ammonium, has better bioaffinity, and is absorbed and utilized more quickly by plants. Fine glufosinate ammonium can mainly inhibit the activity of glutamine synthetase (GS) in plants, thereby hindering the synthesis of glutamine, causing nitrogen metabolism disorders in plants, and thus making it impossible for plants to photosynthesize and die. In addition, the per-acre application rate of fine glufosinate ammonium is only 50% of that of ordinary glufosinate ammonium, which can reduce manpower and material resources and alleviate environmental pressure, and improve the economic efficiency of the product.

[0003] Highly effective halpyrazole (molecular formula C 16 H 13 CIF 3 NO 4 ), molecular weight 375.7, selective herbicide, has significant control effect on perennial grass weeds such as bermudagrass and reed, is safe for broad-leaved weeds, and has stable effect under low temperature and drought conditions.

[0004] Glufosinate-ammonium is a contact herbicide. Although the activity of glufosinate-ammonium is better than that of ordinary glufosinate-ammonium, long-term use will still cause weeds to develop resistance, and the protective effect of glufosinate-ammonium will decrease under low temperature conditions. In order to reduce the increase of resistant weeds, the mixed use of glufosinate-ammonium with other herbicides will become a future development trend.

[0005] At present, there are relevant aqueous solution patents disclosed about the combination of glufosinate ammonium and high-efficiency fluazifop-butyl, such as CN110786338A, but the aqueous solution has large particle size and poor efficacy; Patent CN202210417908 also mentions a microemulsion of glufosinate ammonium and high-efficiency fluazifop-butyl, but its auxiliary agent cost is high, the viscosity is high, the solubility is poor, and it is difficult to ensure low-temperature stability.

[0006] Another common variety on the market is the microemulsion formulation of ordinary glufosinate-ammonium and fluazifop-butyl. This formulation can only exert better efficacy under high temperature and good light conditions, and requires a large amount of organic solvents or polar solvents, which causes great pollution to the environment. Summary of the invention

[0007] The purpose of the present invention is to overcome the above-mentioned shortcomings and provide a high-efficiency adjuvant for a microemulsion of refined glufosinate-ammonium and high-efficiency fluazifop-butyl, which is environmentally friendly, has a small dosage, obvious synergy, low cost and good formulation stability.

[0008] In order to achieve the above-mentioned invention object, the specific technical scheme is as follows:

[0009] A microemulsion adjuvant suitable for compounding refined glufosinate-ammonium with highly effective haloxyfop-butyl, characterized in that the adjuvant is specifically composed of the following components in percentage by mass:

[0010]

[0011] Preferably, the above-mentioned auxiliary agent is composed of the following components in percentage by mass:

[0012]

[0013] The microemulsion auxiliary agent of refined glufosinate ammonium compounded with high-efficiency haloxyfop-butyl described in the present invention is prepared by the following method: weighed alkyl glycoside is added into a reaction kettle, stirring is started, styrylphenol polyoxyethylene ether and fatty alcohol polyoxyethylene ether sodium sulfate are added, heating to 40-50°C and stirring evenly, and then ethylene glycol is added and stirred evenly to obtain the auxiliary agent of refined glufosinate ammonium compounded with high-efficiency haloxyfop-butyl microemulsion.

[0014] The microemulsion prepared by using the adjuvant of the present invention has a small particle size, and the microparticles are between 0.01 and 0.1 microns, and can form a stable unit in plant tissue cells, thereby improving the weed control effect and the utilization rate of the agent.

[0015] In the formula of the present invention, styrylphenol polyoxyethylene ether can be strongly adsorbed on the surface of the pesticide active material particles, while providing electrostatic repulsion and steric hindrance.

[0016] Alkyl polyglycoside has low surface tension and strong wetting power, and can be compounded with anionic and zwitterionic surfactants. When used in the formula of the present invention, it has low viscosity and good solubility, is easier to prepare for multi-component additives, saves production costs, and has obvious synergistic effects; moreover, the use of the alkyl polyglycoside of the present invention can also improve the cloud point of the finished microemulsion preparation, increase the stability of the preparation, and improve the preparation's resistance to strong alkali, strong acid, and hard water; in addition, the alkyl polyglycoside has low toxicity, low irritation to humans and animals, and is safe to the environment.

[0017] Adding sodium fatty alcohol polyoxyethylene ether sulfate into the preparation can make the preparation disperse better in water, and can also reduce the surface tension of the preparation and increase the penetration ability of the preparation.

[0018] Ethylene glycol can make the preparation penetrate and be absorbed into the plant body better, thereby improving the herbicidal effect. The use of ethylene glycol in the present invention can also reduce the freezing point of the preparation and improve the low-temperature stability of the preparation.

[0019] The above-mentioned adjuvant is suitable for compounding microemulsions with 10-20% refined glufosinate-ammonium content and 1-3% high-efficiency haloxyfop-methyl content, preferably 1% high-efficiency haloxyfop-methyl content. The present invention is particularly suitable for compounding low-concentration high-efficiency haloxyfop-methyl with 10-20% refined glufosinate-ammonium.

[0020] The dosage of the above-mentioned auxiliary agent in the compound microemulsion is 20%-30%, preferably 25%. The "%" mentioned in the present invention refers to the mass percentage.

[0021] By adopting the above technical scheme, the additive of the present invention has the following advantages:

[0022] (1) It can increase the penetration capacity of the preparation and improve the efficacy, and the pesticide preparation has good cold and hot storage stability.

[0023] (2) It can reduce the production cost of the preparation and improve the environmental safety of the product.

[0024] The refined glufosinate-ammonium compounded high-efficiency fluazifop-butyl microemulsion processed by using the auxiliary agent of the present invention has the characteristics of high efficiency, safety, high environmental and biological safety, etc., and has good application prospects. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 Photo of microemulsion of application example 1 of the present invention

[0026] Figure 2 This is a photo of the microemulsion of comparative example 1 of the present invention

[0027] Figure 3 This is a photo of the microemulsion of comparative example 2 of the present invention

[0028] Figure 4 These are photos comparing the efficacy of 20% glufosinate aqueous solution (left) and 19% glufosinate + 3% high-efficiency fluazifop-butyl microemulsion (right) (photos before application).

[0029] Figure 5 Comparative photos of the efficacy of 20% glufosinate aqueous solution (left) and 19% glufosinate + 3% high-efficiency haloxyfop-butyl microemulsion (right) (first day after application)

[0030] Figure 6 Comparative photos of the efficacy of 20% glufosinate aqueous solution (left) and 19% glufosinate + 3% high-efficiency haloxyfop-butyl microemulsion (right) (third day after application)

[0031] Figure 7 Comparative photos of the efficacy of 20% glufosinate aqueous solution (left) and 19% glufosinate + 3% high-efficiency haloxyfop-butyl microemulsion (right) (fifth day after application)

[0032] Figure 8Comparative photos of the efficacy of 20% glufosinate aqueous solution (left) and 19% glufosinate + 3% high-efficiency haloxyfop-butyl microemulsion (right) (seventh day after application) DETAILED DESCRIPTION

[0033] The present invention is further described by the following examples, but the present invention is not limited to these examples.

[0034] Example 1

[0035] formula:

[0036]

[0037] The preparation method is as follows: add the weighed alkyl glycoside into the reaction kettle, start stirring, add styrylphenol polyoxyethylene ether and fatty alcohol polyoxyethylene ether sodium sulfate, heat to 40-50°C and stir evenly, then add ethylene glycol and stir evenly to obtain the auxiliary agent of the refined glufosinate ammonium compound high-efficiency flupyrazole microemulsion.

[0038] Example 2

[0039] formula:

[0040]

[0041] The preparation method is as follows: add the weighed alkyl glycoside into the reaction kettle, start stirring, add styrylphenol polyoxyethylene ether and fatty alcohol polyoxyethylene ether sodium sulfate, heat to 40-50°C and stir evenly, then add ethylene glycol and stir evenly to obtain the auxiliary agent of the refined glufosinate ammonium compound high-efficiency flupyrazole microemulsion.

[0042] Example 3

[0043] formula:

[0044]

[0045]

[0046] The preparation method is as follows: add the weighed alkyl glycoside into the reaction kettle, start stirring, add styrylphenol polyoxyethylene ether and fatty alcohol polyoxyethylene ether sodium sulfate, heat to 40-50°C and stir evenly, then add ethylene glycol and stir evenly to obtain the auxiliary agent of the refined glufosinate ammonium compound high-efficiency flupyrazole microemulsion.

[0047] Example 4

[0048] formula:

[0049]

[0050] The preparation method is as follows: add the weighed alkyl glycoside into the reaction kettle, start stirring, add styrylphenol polyoxyethylene ether and fatty alcohol polyoxyethylene ether sodium sulfate, heat to 40-50°C and stir evenly, then add ethylene glycol and stir evenly to obtain the auxiliary agent of the refined glufosinate ammonium compound high-efficiency flupyrazole microemulsion.

[0051] Example 5

[0052] formula:

[0053]

[0054] The preparation method is as follows: add the weighed alkyl glycoside into the reaction kettle, start stirring, add styrylphenol polyoxyethylene ether and fatty alcohol polyoxyethylene ether sodium sulfate, heat to 40-50°C and stir evenly, then add ethylene glycol and stir evenly to obtain the auxiliary agent of the refined glufosinate ammonium compound high-efficiency flupyrazole microemulsion.

[0055] Application Example 1:

[0056] 3% of high-efficiency halpyrazole was dissolved in 5% of xylene, and 25% of the adjuvant of Example 1 was added while stirring, and then mixed with the mother liquor of glufosinate ammonium, and the balance was supplemented with water, and stirring was continued for 0.5h to obtain a light yellow transparent microemulsion containing 19% glufosinate ammonium + 3% high-efficiency halpyrazole (see Figure 1 ).

[0057] The pH value of the preparation ranges from 6.0 to 8.0. There is no stratification or precipitation when cold-stored (0±1°C) or hot-stored (54±2°C) for 14 days, and the cold and hot storage stability is good.

[0058] Application Example 2:

[0059] 1% of high-efficiency halofop-methyl was dissolved in 5% of xylene, and 25% of the adjuvant of Example 3 was added while stirring, and then mixed with the mother solution of glufosinate ammonium, and the balance was supplemented with water. Stirring was continued for 0.5 h to obtain a light yellow and transparent microemulsion containing 19% glufosinate ammonium + 1% high-efficiency halofop-methyl.

[0060] The pH value of the preparation ranges from 6.0 to 8.0. There is no stratification or precipitation when cold-stored (0±1°C) or hot-stored (54±2°C) for 14 days, and the cold and hot storage stability is good.

[0061] Application Example 3:

[0062] 3% of high-efficiency halofop-methyl was dissolved in 5% of xylene, and 25% of the adjuvant of Example 5 was added while stirring, and then mixed with the mother liquor of glufosinate ammonium, and the balance was supplemented with water. Stirring was continued for 0.5 h to obtain a light yellow transparent microemulsion containing 19% glufosinate ammonium + 3% high-efficiency halofop-methyl.

[0063] The pH value of the preparation ranges from 6.0 to 8.0. There is no stratification or precipitation when cold-stored (0±1°C) or hot-stored (54±2°C) for 14 days, and the cold and hot storage stability is good.

[0064] Comparative Example 1

[0065]

[0066] Preparation method: add the weighed alkyl glycoside into the reaction kettle, start stirring, add lauroylpropyl dimethyl betaine and sodium polyoxyethylene fatty alcohol ether sulfate, heat to 40-50°C and stir evenly, then add ethylene glycol and stir evenly to obtain the adjuvant of the refined glufosinate-ammonium compound high-efficiency fluazifop-butyl microemulsion.

[0067] 3% of highly effective halofop-methyl was dissolved in 5% of xylene, and 25% of the adjuvant of Example 1 was added while stirring, and then the refined glufosinate mother liquor was mixed, and the balance was supplemented with water, and stirring was continued for 0.5h. Due to the addition of lauroylpropyl dimethyl betaine, the stability of the preparation was deteriorated, and the prepared microemulsion of 19% refined glufosinate + 3% highly effective halofop-methyl was turbid (see Figure 2 ).

[0068] Comparative Example 2

[0069]

[0070] Preparation method: add the weighed alkyl glycoside into the reaction kettle, start stirring, add octadecyl trimethyl ammonium chloride and sodium polyoxyethylene fatty alcohol ether sulfate, heat to 40-50°C and stir evenly, then add ethylene glycol and stir evenly to obtain the adjuvant of the refined glufosinate ammonium compound high-efficiency flupyrazole microemulsion.

[0071] 3% of highly effective halpyrazole was dissolved in 5% of xylene, 25% of the adjuvant of Example 1 was added under stirring, and then the refined glufosinate mother liquor was mixed, and the balance was supplemented with water, and stirring was continued for 0.5h. Due to the addition of octadecyltrimethylammonium chloride, the stability of the preparation was deteriorated, and the prepared microemulsion of 19% refined glufosinate + 3% highly effective halpyrazole was turbid (see Figure 3 ).

[0072] Example 6

[0073] Field efficacy test

[0074] Test agents: 19% glufosinate-ammonium+3% high-efficiency fluazifop-butyl microemulsion in Example 1, and commercially available 20% glufosinate-ammonium aqueous solution.

[0075] Targets of control: Setaria viridis, Erigeron chinensis, Sonchus endive, etc.

[0076] Experimental design: The experiment was set up with two treatments, calculated by active ingredients, A: 20% glufosinate aqueous solution 200g / mu, B: 19% glufosinate + 3% high-efficiency halpyrazole microemulsion 200g / mu. Each treatment was repeated 3 times, and each plot was 30m 2 .

[0077] Application and survey method: Back-mounted automatic sprayer, 30L of water per mu (667㎡) was used for uniform spraying. The experiment was conducted in Nanjing in June 2024. The types and numbers of weeds were investigated 1d, 3d, 5d, and 7d after application, and the control effect was calculated. Samples were taken at 3 points in each plot during the survey, and the sample area was 1m 2 .

[0078] Control effect = (number of weeds in the control area - number of weeds in the treatment area) / number of weeds in the control area × 100% test results

[0079] Table 1 Effect of different treatments on the control of weeds in non-cultivated land

[0080]

[0081] From the above data results obtained from the field efficacy test, it can be seen that the post-drug control effect of the 19% refined glufosinate ammonium + 3% high-efficiency halpyrazole microemulsion prepared by the present invention is significantly better than the commercially available 20% refined glufosinate ammonium aqueous solution, and can effectively prevent weeds in non-cultivated land (the control effect is shown in Figure 4-8 ).

Claims

1. An adjuvant suitable for preparing a highly effective haloxyfop-butyl microemulsion of glufosinate ammonium, characterized in that The additive is composed of the following components in percentage by mass:

2. The adjuvant suitable for preparing a highly effective haloxyfop-butyl microemulsion of glufosinate-ammonium according to claim 1, characterized in that The additive is composed of the following components in percentage by mass:

3. The adjuvant suitable for the high-efficiency haloxyfop-butyl compounded microemulsion according to any one of claims 1 to 2, characterized in that The auxiliary agent is suitable for a compound microemulsion with a content of 10-20% of refined glufosinate ammonium and 1-3% of high-efficiency haloxyfop-butyl.

4. A method for preparing an adjuvant suitable for the microemulsion of high-efficiency haloxyfop-butyl compounded with refined glufosinate-ammonium as claimed in any one of claims 1 to 2, characterized in that The method comprises the following steps: adding alkyl glycoside into a reaction kettle, starting stirring, adding styrylphenol polyoxyethylene ether and fatty alcohol polyoxyethylene ether sodium sulfate, heating to 40-50°C and stirring evenly, and then adding ethylene glycol and stirring evenly to obtain a refined glufosinate-ammonium compounded high-efficiency fluazifop-butyl microemulsion adjuvant.

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