Traditional Chinese medicinal liquor for treating pharyngitis and tonifying Yang and preparation method thereof

Abstract

The invention provides traditional Chinese medicinal liquor for treating pharyngitis and tonifying Yang and a preparation method thereof, and relates to the technical field of traditional Chinese medicinal liquor, the traditional Chinese medicinal liquor is prepared from the following raw materials: cistanche powder, licorice powder, wolfberry powder, red date powder, onion powder and edible white spirit; the cistanche powder has the effects of tonifying kidney yang and benefiting essence and blood; the Chinese wolfberry powder has the effects of nourishing kidney and liver and improving sexual function; the red date powder has the effects of tonifying middle-Jiao and Qi and nourishing blood and tranquilizing mind; the licorice powder can tonify spleen and qi, clear away heat and toxic materials and relieve pharyngitis symptoms; the onion powder is rich in various anti-inflammatory and sterilizing substances, and plays a role in regulating pharyngitis; the raw materials adopted by the invention are all natural materials, are reasonable in compatibility, small in side effect and low in cost, and are beneficial to relieving pharyngeal inflammation and pain, comprehensively conditioning sexual dysfunction and treating both symptoms and root causes after being matched with the edible white spirit.

Description

Technical Field

[0001] The invention relates to the technical field of Chinese medicinal wine, and in particular to a Chinese medicinal wine for treating pharyngitis and strengthening yang and a preparation method thereof. Background Art

[0002] Pharyngitis is a common upper respiratory tract disease, which can be divided into acute pharyngitis and chronic pharyngitis. Acute pharyngitis is usually caused by viral or bacterial infection. The patient's pharyngeal mucosa and submembranous tissues have acute inflammatory reactions, and the pharyngeal lymph nodes are involved. Symptoms include pharyngeal pain, dysphagia, fever, etc. Chronic pharyngitis is chronic congestion of the mucosal layer, which is mostly caused by repeated attacks of acute pharyngitis, long-term smoking and drinking, environmental stimulation, allergies and other factors. Symptoms include foreign body sensation in the throat, dryness, itching, irritating cough, etc.

[0003] At present, the treatments for pharyngitis mainly include drug therapy and local treatment; however, commonly used drug treatments include antibiotics, antiviral drugs, anti-inflammatory drugs, lozenges, etc., but these drugs may have side effects and are prone to drug resistance after long-term use; local treatments such as nebulization inhalation, although they can directly act on the pharynx, often require the support of professional equipment and medical institutions, and are costly.

[0004] With the accelerated pace of life, aging and the influence of bad living habits, sexual dysfunction, especially the need for impotence, is becoming increasingly common among men. Impotence is not only related to the quality of sex life, but also has an important impact on men's self-confidence and mental health.

[0005] At present, most of the existing methods of strengthening male sexual function are drug treatment. However, Western medicine for strengthening male sexual function may cause side effects such as headache, facial flushing, and visual abnormalities, and is not suitable for long-term use.

[0006] Chinese medicinal liquor has a long history of application and is an important part of traditional Chinese medicine. Medicinal liquor dissolves the active ingredients of Chinese medicine in liquor, and with the help of the pungent, dispersing, warming and unblocking properties of liquor, it can enhance the efficacy of the medicine and improve its absorption rate. Although there are some Chinese medicinal liquors on the market that claim to have the effect of treating pharyngitis or strengthening yang, most products have problems such as incompatibility, treating symptoms but not the root cause, uneven quality of medicinal materials, and non-standard production processes, resulting in unstable efficacy and difficult to guarantee safety. Summary of the invention

[0007] The purpose of the invention is to provide a Chinese medicinal wine for treating pharyngitis and strengthening yang and a preparation method thereof, so as to solve the technical problems existing in the prior art.

[0008] In order to achieve the above-mentioned object of the invention, the technical solution adopted by the present invention is:

[0009] A Chinese medicinal wine for treating pharyngitis and strengthening yang and a preparation method thereof comprises the following raw materials: cistanche powder, licorice powder, wolfberry powder, red date powder, onion powder and edible liquor.

[0010] Furthermore, the weight of the raw materials is: 2-4g of Cistanche powder, 1-4g of licorice powder, 2-4g of wolfberry powder, 9-14g of red date powder, 11-14g of onion powder, and 150-380g of edible liquor.

[0011] Furthermore, the weight of the raw materials is: 4g of Cistanche powder, 4g of licorice powder, 4g of wolfberry powder, 13g of red date powder, 14g of onion powder, and 350g of edible white wine.

[0012] Furthermore, the preparation method includes the following: S1: processing raw materials, washing Cistanche deserticola, licorice, wolfberry, red dates and onions, drying them, and then putting the dried raw materials into a grinding device and grinding them into powder, and weighing the raw material powder according to a preset ratio; S2: soaking, putting the raw material powder weighed in S1 into a clean container, adding 150-380g of edible liquor to form a mixed liquid, sealing the container, and soaking for 40-60 days; S3: shaking regularly, shaking the container in S2 every 10 days; S4: filtering, using a filtering device to filter the mixed liquid after soaking, removing the residue of the raw materials, and obtaining medicinal wine; S5: sealing, putting the medicinal wine into a wine bottle and sealing it.

[0013] Furthermore, the edible liquor in S2 weighs 350 g and has an alcohol content of 20-53°.

[0014] Furthermore, the filtering device in S4 is a filter screen, and the filter screen is a nylon filter screen or a stainless steel filter screen.

[0015] Compared with the prior art, the present invention has the following beneficial effects:

[0016] (1) The Cistanche deserticola powder in the present invention has the effects of nourishing kidney yang and benefiting essence and blood; wolfberry powder has the effects of nourishing kidney and liver and improving sexual function; red date powder has the effects of nourishing the middle and replenishing qi and nourishing blood and calming the mind; licorice powder can nourish the spleen and replenish qi, clear away heat and detoxify, and help alleviate the symptoms of pharyngitis; onion powder is rich in a variety of anti-inflammatory and sterilizing substances, which has a regulating effect on pharyngitis; and the raw materials used in the present invention are all natural materials, with reasonable compatibility, small side effects, low cost, and after being consumed with white wine, it helps to alleviate pharyngeal inflammation and pain; the present invention can perform comprehensive conditioning on sexual dysfunction in clinical practice, treating both the symptoms and the root causes;

[0017] (ii) The preparation method of the present invention is simple, has low treatment cost, high safety, and has wide universality. DETAILED DESCRIPTION

[0018] In order to make the purpose, technical solution and technical effect of the present invention more clear, the specific embodiments of the present invention are described below. It should be understood that the specific embodiments described here are only used to explain the present invention and are not used to limit the present invention.

[0019] This embodiment provides a Chinese medicinal wine for treating pharyngitis and strengthening yang and a preparation method thereof, which is made from the following raw materials: Cistanche powder, licorice powder, wolfberry powder, red date powder, onion powder, and edible liquor, and the specific effects are as follows:

[0020] Cistanche powder: has the effects of nourishing kidney yang, improving blood essence, and moistening the intestines and relieving constipation;

[0021] Licorice powder: has the effects of tonifying the spleen and replenishing qi, clearing away heat and detoxifying, removing phlegm and relieving cough, relieving urgency and relieving pain, harmonizing various medicines, anti-inflammatory, anti-allergic, and anti-ulcer;

[0022] Lycium barbarum powder: nourishes the liver and kidneys, improves the eyesight, resists oxidation, regulates immunity, and protects the reproductive system;

[0023] Red date powder: has the effects of nourishing the middle qi, nourishing blood and calming the mind, strengthening the physique, improving blood supply and regulating the nervous system;

[0024] Onion powder: has anti-inflammatory, antioxidant, lipid-lowering and blood sugar-lowering effects;

[0025] Embodiment 1:

[0026] The present embodiment provides a Chinese medicinal wine for treating pharyngitis and strengthening yang and a preparation method thereof, wherein the weight of the raw materials is: 2-4g of Cistanche deserticola powder, 1-4g of licorice powder, 2-4g of wolfberry powder, 9-14g of red date powder, 11-14g of onion powder, and 150-380g of edible liquor;

[0027] S1: Raw material processing, after washing Cistanche deserticola, licorice, wolfberry, red dates and onions, they are dried, and then the dried raw materials are put into a grinding device and ground into powder, and the raw material powder is weighed according to a preset ratio; the Cistanche deserticola contains a variety of biologically active ingredients, such as ethanol glycosides and cyclopentane ether terpenes, which have a good therapeutic effect on sexual dysfunction; the main components of licorice are glycyrrhizic acid and glycyrrhizin, which have significant medicinal effects after grinding; the wolfberry contains wolfberry polysaccharides, betaine, vitamins and other ingredients, which have the function of protecting the reproductive system; the red dates are rich in nutrients such as vitamin C, vitamin P, polysaccharides, amino acids, etc.; the raw materials are ground into powder so as to better absorb the effective ingredients in edible liquor and fully mix with the edible liquor to improve the absorption rate;

[0028] S2: Soaking, placing the raw material powder weighed in S1 into a clean container, adding 150-380 g of edible liquor with a degree of 20-53° to form a mixed liquid, sealing the container, and soaking for 40-60 days;

[0029] S3: Shake regularly, shaking the container in S2 every 10 days to promote effective mixing of the raw materials and edible liquor;

[0030] S4: filtering, using a filtering device to filter the mixed solution after the soaking is completed, removing the residue of the raw materials, and obtaining the medicinal wine;

[0031] S5: Seal, put the medicinal wine into the bottle and seal it.

[0032] It should be noted that the grinding device includes a Chinese medicine crusher or a manual grinding mortar and a manual grinding pestle. The medicine crusher, manual grinding mortar and manual grinding pestle are all prior art and will not be described in detail here.

[0033] Embodiment 2:

[0034] The present embodiment provides a Chinese medicinal wine for treating pharyngitis and strengthening yang and a preparation method thereof, wherein the weight of the raw materials is: 4g of Cistanche powder, 4g of licorice powder, 4g of wolfberry powder, 13g of red date powder, 14g of onion powder, and 350g of edible liquor;

[0035] S1: Raw material processing, after washing Cistanche deserticola, licorice, wolfberry, red dates and onions, they are dried, and then the dried raw materials are put into a grinding device and ground into powder, and the raw material powder is weighed according to a preset ratio; the Cistanche deserticola contains a variety of biologically active ingredients, such as ethanol glycosides and cyclopentane ether terpenes, which have a good therapeutic effect on sexual dysfunction; the main components of licorice are glycyrrhizic acid and glycyrrhizin, which have significant medicinal effects after grinding; the wolfberry contains wolfberry polysaccharides, betaine, vitamins and other ingredients, which have the function of protecting the reproductive system; the red dates are rich in nutrients such as vitamin C, vitamin P, polysaccharides, amino acids, etc.; the raw materials are ground into powder so as to better absorb the effective ingredients in edible liquor and fully mix with the edible liquor to improve the absorption rate;

[0036] S2: Soaking, putting the raw material powder weighed in S1 into a clean container, adding 350g of 53° alcoholic liquor to form a mixed liquid, sealing the container, and soaking for 40-60 days;

[0037] S3: Shake regularly, shaking the container in S2 every 10 days to promote effective mixing of the raw materials and edible liquor;

[0038] S4: filtering, using a filter to filter the mixed solution after the soaking is completed, removing the residue of the raw materials, and obtaining the medicinal wine;

[0039] S5: Seal, put the medicinal wine into the bottle and seal it.

[0040] Preferably, the filter is a nylon filter or a stainless steel filter, and the nylon filter and the stainless steel filter will not chemically react with the ingredients in the medicinal wine, thereby ensuring the quality and safety of the medicinal wine.

[0041] Clinical trials of the present invention in the treatment of pharyngitis:

[0042] Study time: January 2019 - October 2020, 100 patients with pharyngitis were randomly divided into an observation group and a control group. The data of the two groups of patients are as follows:

[0043] (1) Control group: 50 patients, including 28 males and 22 females, aged 22 to 63 years old (mean age: (45.15±1.37) years old). The shortest course of disease was 2 months, the longest was 15 years, and the mean course of disease was (7.14±2.33) years.

[0044] (2) Observation group: 50 patients, including 29 males and 21 females, aged 21 to 64 years old (mean age: (45.23+1.19) years old). The shortest course of disease was 1 month and the longest was 16 years (mean course of disease: (7.22+2.18) years).

[0045] Inclusion criteria:

[0046] (1) All patients met the clinical diagnostic criteria for pharyngitis;

[0047] (2) All patients had confirmed diseases through clinically relevant diagnoses;

[0048] (3) All patients were able to communicate autonomously;

[0049] (4) did not receive other treatment during enrollment;

[0050] (5) This study was approved by the Medical Ethics Committee;

[0051] (6) All patients agreed to the treatment and signed the informed consent form;

[0052] Exclusion criteria:

[0053] (1) Pregnant or lactating patients;

[0054] (2) Those with mental disorders are unable to communicate independently;

[0055] (3) Those suffering from severe heart, lung, liver, kidney and other functional disorders;

[0056] (4) those with poor compliance;

[0057] (5) Those who are allergic to alcohol;

[0058] Test method:

[0059] The treatment method for patients in the control group was to take compound coral grass tablets sublingually, 0.8g each time, 6 times a day.

[0060] The treatment method for patients in the observation group is the Chinese medicinal wine proposed by the present invention, which consists of red date powder, onion powder, licorice powder, wolfberry powder, Cistanche powder, and edible white wine 20-53°. Take 100 ml daily, with dinner.

[0061] It should be noted that both groups of patients were treated for half a month.

[0062] Observation range:

[0063] The treatment effects of the above patients were analyzed. Marked effect means that the pharyngeal symptoms of the patients completely disappeared after treatment, and the symptoms of effective patients were improved; ineffective patients did not meet the above criteria.

[0064] The symptom improvement time was compared between the two groups of patients.

[0065] Statistical methods:

[0066] The data conformed to the normal distribution, and the variances of each group were homogeneous. The variance analysis of random block groups was directly used. If the test results were statistically significant, further pairwise comparisons were performed using the LSD method. Results:

[0067]

[0068] (Table 1) Treatment effects of the two groups of patients

[0069] Group Number of cases Clinical symptom improvement time Observation Group 50 8.49±1.61 Control group 50 14.35±2.82 P-value <0.05

[0070] (Table 2) Time of improvement of clinical symptoms of patients

[0071] (1) Analysis of the treatment effects of the above patients shows that the treatment effect of the observation group is better than that of the patients in the observation group, as shown in Table 1. (2) Comparison of the improvement time of clinical symptoms of the two groups of patients shows that the improvement time of symptoms of the observation group is faster than that of the patients in the observation group, as shown in Table 2.

[0072] Clinical trials of the present invention in terms of impotence:

[0073] The selection conditions for the test subjects are as follows:

[0074] (1) Male, 40–70 years old;

[0075] (2) No hypertension, hyperlipidemia, or diabetes;

[0076] (3) Volunteer participants;

[0077] (4) Number of test subjects (as shown in Table 3): 23 subjects took the Chinese medicinal liquor proposed by the present invention at a dosage of 100 mL / d per subject, and the taking time was the same as dinner.

[0078] age 40-50 years old 51-60 years old 61-70 years old Number of people 5 people 12 people 6 people

[0079] Table (3) Number of experimental subjects selected

[0080] Test result record sheet:

[0081] There are 5 levels of penis hardness grading, and the test is performed once before taking the medicine. The test is performed once a day after taking the medicine. The aphrodisiac score of the Chinese medicinal wine proposed by the present invention is statistically shown in Table 4 when 100 mL of the wine is taken daily. The test results are as follows: the average score of 10 times after taking the medicine is taken.

[0082] Criteria for judging the efficacy of the trial:

[0083] Average score after taking the medicine - score before taking the medicine = efficacy after taking the medicine

[0084] The difference <2 means ineffective; 3>22 means effective; the difference ≥3 means significant effect. In Table 4, the average is 4.6 points, 4.6-1=3.6 (significant effect), and the scores of 23 testers who took the Chinese medicinal wine proposed by the present invention before and after taking 100 mL of the medicine every day are shown in Table 5.

[0085]

[0086] (Table 4) Statistics of the aphrodisiac scores of the present invention after taking 100 mL daily

[0087]

[0088]

[0089] (Table 5) Statistics of scores of 23 people before and after taking 100 mL of aphrodisiac daily

[0090] 1. Establish test hypothesis and determine test level

[0091] :μ d =0, the difference in evaluation scores before and after taking the medicine is zero.

[0092] :μ d ≠0, the difference in evaluation scores before and after taking the medicine is not zero.

[0093] α=0.05

[0094] 2. Calculate the test statistic

[0095] First calculate the difference d and d 2 , as shown in the fourth and fifth columns of Table 5.

[0096] After calculation:

[0097] Σd=66.4,Σd 2 =200.02,

[0098]

[0099] Calculate the standard error of the difference

[0100]

[0101] 3. Make inferences based on P values

[0102] Degree of freedom V = n-1 = 23-1 = 22, from the table: t 0.05 , 22 = 1.717

[0103] In this case, t>t 0.05 , 22, P<0.05, the difference is statistically significant, rejected, accepted, it can be considered that the present invention is effective in strengthening sexual function clinically.

[0104] Number of test subjects: 23 people The results of this test are as follows: Table 6

[0105] Effect invalid Effective Significant therapeutic effect Number of people 2 people 13 people 8 people

[0106] (Table 6) Number of subjects selected

[0107] Effective rate: (13+8)-(2+13+8)x100%=91.3%

[0108] Conclusion of the experiment: In modern society, the pace of life is accelerating. When people reach middle age and have achieved success in their careers, their physical functions gradually weaken. In particular, men have greater work and life pressures, and their sexual functions gradually weaken, resulting in an increasing number of impotence. This situation needs to be solved urgently. Therefore, we prefer Chinese medicinal materials that are non-toxic and have no side effects and are easy to take. The Chinese medicinal wine proposed by the present invention, which can play a role in male sexual enhancement, was clinically observed.

[0109] We conducted clinical observations on the Chinese medicinal wine proposed in this invention. 0.05 , P<0.05, the difference is statistically significant, it can be considered that the Chinese medicinal wine proposed by the present invention is effective in strengthening male sexual function clinically. The clinical efficacy of the Chinese medicinal wine proposed by the present invention is 91.3%.

[0110] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention shall be included in the protection scope of the present invention.

Claims

1. A Chinese medicinal wine for treating pharyngitis and strengthening sexual function and a preparation method thereof, characterized in that: The product is made from the following raw materials: Cistanche powder, licorice powder, wolfberry powder, red date powder, onion powder and edible white wine.

2. The Chinese medicinal liquor for treating pharyngitis and strengthening sexual function according to claim 1, wherein: The weight of the raw materials is: 2-4g of Cistanche powder, 1-4g of licorice powder, 2-4g of wolfberry powder, 9-14g of red date powder, 11-14g of onion powder, and 150-380g of edible liquor.

3. The Chinese medicinal wine for treating pharyngitis and strengthening sexual function according to claim 3 and its preparation method, characterized in that: The weight of the raw materials is: 4g of Cistanche powder, 4g of licorice powder, 4g of wolfberry powder, 13g of red date powder, 14g of onion powder, and 350g of edible white wine.

4. The Chinese medicinal liquor for treating pharyngitis and strengthening sexual function according to any one of claims 1 to 3 and its preparation method, characterized in that: The invention comprises the following preparation methods: S1: Raw material processing, after washing the Cistanche deserticola, licorice, wolfberry, red dates and onion, drying them, and then putting the dried raw materials into a grinding device to grind them into powder, and weighing the raw material powder according to a preset ratio; S2: Soaking, placing the raw material powder weighed in S1 into a clean container, adding 150-380 g of edible liquor to form a mixed liquid, sealing the container, and soaking for 40-60 days; S3: Shake regularly, shaking the container in S2 every 10 days; S4: filtering, using a filtering device to filter the mixed solution after the soaking is completed, removing the residue of the raw materials, and obtaining the medicinal wine; S5: Seal, put the medicinal wine into the bottle and seal it.

5. The Chinese medicinal wine for treating pharyngitis and strengthening sexual function according to claim 4, and its preparation method, characterized in that: The edible liquor in S2 weighs 350g and has an alcohol content of 20-53°.

6. The Chinese medicinal wine for treating pharyngitis and strengthening sexual function according to claim 4 and its preparation method, characterized in that: The filtering device in S4 is a filter screen, and the filter screen is a nylon filter screen or a stainless steel filter screen.

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