Medicine particle size analysis and detection device
The device addresses the inefficiencies of manual mixing in drug particle size analysis by incorporating automated components for precise and uniform mixing, improving accuracy and efficiency in drug particle size detection.
Patent Information
- Application Number
- CN202411459534.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-18
- Publication Date
- 2025-01-03
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Existing drug particle size analysis and detection methods rely on manual mixing of drug powder with solvent, which introduces human error, affects accuracy, and lacks consistency and repeatability, thereby reducing efficiency.
A drug particle size analysis and detection device with automated components for precise drug and solvent mixing, including a laser particle size analyzer, pretreatment box, mixing assembly, and oscillating component to ensure uniform dispersion of drug particles.
The device improves accuracy, flexibility, and efficiency by automating the mixing process, ensuring consistent and repeatable results, reducing human error, and enhancing the precision of particle size analysis.
Smart Images

Figure CN119246349A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of drug particle size analysis and detection, and in particular to a drug particle size analysis and detection device. Background Art
[0002] The drug particle size analysis and detection device is mainly used to measure the size, distribution and other physical properties of drug particles. It is an indispensable and important tool in the drug research and development and production process. The drug particle size analysis and detection device mainly includes laser particle size analyzers, microparticle laser particle size analyzers and other types. They use different principles and technical means to achieve accurate measurement of drug particle size.
[0003] Chinese patent publication number CN117092000A discloses a drug particle size analysis and detection device and method, including a shell and multiple drug classification mechanisms, the drug classification mechanisms include a driving component, a cam, a screen installation frame, a drug screening net and multiple reset springs, the shell provides installation conditions for the multiple drug classification mechanisms, and the drugs can be classified through the multiple drug classification mechanisms. The drug screening nets on each drug classification mechanism have different apertures, and the apertures decrease from top to bottom. When the drugs need to be screened, the raw materials are poured into the feed port on the shell, the driving component is started, and the driving component drives the cam to rotate. The cam pushes the screen installation frame to slide in the shell, and the rebound force of the multiple reset springs pushes the screen installation frame to abut against the cam, thereby realizing the screening of the raw materials in the drug screening net, thereby solving the problem of low efficiency of existing drug classification.
[0004] The above scheme still has the following shortcomings when used in practice: in the drug particle size analysis and testing process, in order to ensure the accuracy and reliability of the particle size analysis results, the staff must first mix the drug powder or granules with the water solvent, and this mixing process needs to achieve a high degree of uniformity. However, the above drug particle size analysis and testing method relies on manual operation, which not only increases the workload, but also introduces the risk of errors caused by human factors. The staff needs to strictly control the ratio of the drug and the solvent during the mixing process. Any slight deviation may affect the final analysis results. In addition, manual mixing is difficult to ensure the consistency and repeatability of each operation, which restricts the efficiency of the entire testing process. Summary of the invention
[0005] The present invention aims to solve the above technical problems and provides a drug particle size analysis and detection device, which is simple to operate and has high precision during the drug preparation process.
[0006] The technical solution of the present invention is:
[0007] A drug particle size analysis and detection device, comprising:
[0008] Laser particle size analyzer;
[0009] A pretreatment box, fixedly mounted on the side wall of the laser particle size analyzer;
[0010] A bracket, fixedly mounted on the inner wall of the pretreatment box;
[0011] A material storage box, arranged on one side of the top surface of the pretreatment box;
[0012] A feeding hopper is fixedly mounted on the inner top wall of the pretreatment box, and the top end of the feeding hopper is connected to the storage box;
[0013] A liquid storage tank, arranged on the other side of the top surface of the pretreatment tank;
[0014] A feeding assembly is arranged on the support;
[0015] A mixing assembly is arranged inside the pre-treatment box and at a position on one side of the bracket;
[0016] The oscillating component is arranged directly below the mixing component.
[0017] Furthermore, the feeding assembly comprises:
[0018] A support rod rotatably mounted on the inner side wall of the bracket;
[0019] A connecting plate, fixedly mounted on the top end of the support rod;
[0020] An adjusting plate, slidably sleeved on the outer wall of the support rod;
[0021] Four openings are symmetrically arranged in groups of two on the top surfaces of the connecting plate and the adjusting plate;
[0022] Two guide sleeves are respectively fixedly mounted on the inner side walls of the two openings of the connecting plate;
[0023] Two adjusting sleeves are fixedly mounted on the bottom surface of the adjusting plate at the two opening positions, and the adjusting sleeves are fitted with the corresponding guide sleeves;
[0024] Two cover plates are rotatably mounted on the bottom ends of the two adjusting sleeves through a rotating shaft and a torsion spring;
[0025] Two support blocks are fixedly mounted in the radial direction of the two cover plates;
[0026] A connecting sleeve is slidably sleeved on the outer wall of the support rod, and the top end of the connecting sleeve is fixedly connected to the bottom surface of the adjusting plate;
[0027] A guide ring, fixedly mounted on the bottom surface of the adjustment plate;
[0028] An inclined surface is arranged on the outer wall of the guide ring;
[0029] An adjusting mechanism, arranged on the outer wall of the connecting sleeve;
[0030] The driving mechanism is arranged at the bottom end of the support rod.
[0031] Furthermore, the regulating mechanism comprises:
[0032] A fixing frame, fixedly mounted on the inner wall of the pretreatment box;
[0033] A lifting plate, slidably mounted on the inner wall of the fixing frame;
[0034] A transmission rod is provided through the side wall of the pretreatment box;
[0035] A transmission gear, fixedly mounted on one end of the transmission rod located inside the pretreatment box;
[0036] A knob, fixedly mounted on one end of the transmission rod located outside the pretreatment box;
[0037] A connecting frame, fixedly mounted on the top of the lifting plate, and one end of the connecting frame away from the lifting plate is fixedly connected to the connecting sleeve;
[0038] A plurality of tooth grooves are arranged in a linear array and distributed up and down on a side of the lifting plate opposite to the transmission gear, and the tooth grooves are meshed with the transmission gear.
[0039] Furthermore, the driving mechanism comprises:
[0040] A follower gear is fixedly mounted on the bottom end of the support rod;
[0041] A mounting plate, fixedly mounted on the bottom surface of the follower gear;
[0042] A driving motor is fixedly mounted on the bottom surface of the pre-processing box, and an output end of the driving motor passes through the bottom surface of the pre-processing box;
[0043] A semicircular plate is fixedly mounted on the output end of the driving motor, and arc grooves adapted to the semicircular plate are provided at both ends of the mounting plate;
[0044] The driving half gear is fixedly mounted on the top surface of the semicircular plate, and the driving half gear is meshed with the follower gear.
[0045] Further, the mixing assembly comprises:
[0046] A support frame, fixedly mounted on the inner wall of the pretreatment box;
[0047] A mixing bucket, threadedly mounted on the inner wall of the support frame;
[0048] A fixed gear ring, fixedly sleeved on the outer wall of the mixing bucket;
[0049] An adjusting gear is rotatably mounted on a corner of the top surface of the support frame;
[0050] The servo motor is fixedly mounted at a corner of the bottom surface of the support frame, and the output end of the servo motor is fixedly connected to the adjusting gear.
[0051] Furthermore, the mixing assembly also includes:
[0052] A sealing ring, fixedly mounted on the inner wall of the discharging end of the mixing hopper;
[0053] A fixing rod, fixedly mounted on the inner wall of the sealing ring;
[0054] A sliding rod, which is arranged through an end of the fixing rod away from the end connected with the sealing ring;
[0055] A sealing plug, fixedly mounted on the top of the sliding rod;
[0056] A spring, which is sleeved on the sliding rod and located below the fixed rod, and two ends of the spring are fixedly connected to the sliding rod and the fixed rod respectively;
[0057] The bottom plate is fixedly mounted on the bottom end of the sliding rod.
[0058] Furthermore, the oscillating component comprises:
[0059] A transmission column, rotatably mounted on the inner bottom wall of the pretreatment box;
[0060] An oscillating motor is fixedly mounted on the bottom surface of the pretreatment box, and an output end of the oscillating motor is fixedly connected to the bottom end of the transmission column;
[0061] A connecting rod, fixedly mounted on a side edge of the top surface of the transmission column;
[0062] A mixing tank, fixedly mounted on the top end of the connecting rod;
[0063] A discharge pipe is fixedly mounted on the bottom surface of the mixing tank, and the discharge pipe is communicated with the mixing tank;
[0064] A push rod is fixedly mounted on the inner wall of the feeding end of the mixing tank.
[0065] Furthermore, a liquid adding pipe is provided through the bottom surface of the liquid storage tank, and one end of the liquid adding pipe away from the liquid storage tank is located directly above the mixing bucket.
[0066] Furthermore, the mixing tank is arranged at an angle, and a control valve is installed on the discharge pipe.
[0067] Furthermore, an operation port is provided on the side of the pretreatment box.
[0068] The beneficial effects of the present invention are:
[0069] 1. By setting the feeding component and turning the knob, the sliding of the lifting plate is realized by utilizing the meshing of the transmission rod, the transmission gear and the tooth groove, and then the position of the adjustment plate on the support rod is adjusted, so the dosage of the medicine can be accurately controlled, thereby improving the accuracy and flexibility of drug detection. The cooperation of the semicircular plate and the mounting plate, as well as the meshing of the driving semi-gear and the follower gear, realizes the 180° rotation of the support rod, automatically completes the drug transfer process, improves work efficiency and convenience of operation, when the support rod rotates to a specific position, the support block slides along the inclined surface of the guide ring, triggers the torsion spring to drive the cover plate to rotate, automatically opens the bottom of the adjusting sleeve, realizes the automatic release of the medicine, avoids the tedious manual operation, and improves the automation and safety of the equipment.
[0070] 2. By setting up a mixing component, the drug and the aqueous solvent can be preliminarily mixed through a mixing bucket. Driven by a servo motor, the mixing bucket can rotate and move vertically along the support frame by adjusting the meshing of the gear and the fixed gear ring, so that the mixing bucket can accurately dock with the mixing tank, ensuring efficient transfer of the mixture, while simplifying the structure and reducing failure points.
[0071] 3. By setting up an oscillation component and turning on the oscillation motor, the mixing tank is driven to rotate, and the oscillation effect is achieved by setting the position of the connecting rod. This physical oscillation method promotes the uniform dispersion of drug particles in the mixture, improves the mixing efficiency, and ensures the accuracy of particle size analysis. BRIEF DESCRIPTION OF THE DRAWINGS
[0072] Figure 1 It is a structural schematic diagram of the present invention;
[0073] Figure 2 for Figure 1 Schematic diagram of the structure of the pretreatment box;
[0074] Figure 3 for Figure 2 Schematic diagram of the internal structure of the pretreatment box I;
[0075] Figure 4 for Figure 2 Schematic diagram of the internal structure of the pretreatment box II;
[0076] Figure 5 for Figure 2 Schematic diagram of the middle drive mechanism structure;
[0077] Figure 6 for Figure 4 The middle A section issues large pictures;
[0078] Figure 7 for Figure 3 Schematic diagram of the coordination structure between the mixing component and the oscillating component;
[0079] Figure 8 for Figure 7 A cross-sectional view of the intermediate mixing bucket;
[0080] Fig. 9 for Figure 7 Schematic diagram of the mixing tank structure.
[0081] In the figure: 1, laser particle size analyzer; 2, pretreatment box; 3, bracket; 4, storage box; 5, hopper; 6, liquid storage box; 71, support rod; 72, connecting plate; 73, adjustment plate; 74, opening; 75, guide sleeve; 76, adjustment sleeve; 77, cover plate; 78, support block; 79, connecting sleeve; 710, guide ring; 711, inclined plane; 81, fixed frame; 82, lifting plate; 83, transmission rod; 84, transmission gear; 85, knob; 86, connecting frame; 87, tooth groove; 91, follower gear; 92, Mounting plate; 93, driving motor; 94, semicircular plate; 95, driving half gear; 101, supporting frame; 102, mixing bucket; 103, fixed gear ring; 104, adjusting gear; 105, servo motor; 106, sealing ring; 107, fixed rod; 108, sliding rod; 109, sealing plug; 1010, spring; 1011, bottom plate; 111, transmission column; 112, oscillation motor; 113, connecting rod; 114, mixing tank; 115, discharge pipe; 116, ejector rod; 12, liquid adding pipe; 13, operation port. DETAILED DESCRIPTION
[0082] like Figure 1-Figure 9As shown, a drug particle size analysis and detection device includes a laser particle size analyzer 1; a pretreatment box 2, fixedly mounted on the side wall of the laser particle size analyzer 1, and an operation port 13 is opened on the side of the pretreatment box 2; a bracket 3, fixedly mounted on the inner side wall of the pretreatment box 2; a storage box 4, arranged on one side of the top surface of the pretreatment box 2; a feeding hopper 5, fixedly mounted on the inner top wall of the pretreatment box 2, and the top of the feeding hopper 5 is connected to the storage box 4; a liquid storage box 6, arranged on the other side of the top surface of the pretreatment box 2; a feeding component, arranged on the bracket 3; a mixing component, arranged inside the pretreatment box 2 at a position on one side of the bracket 3; an oscillation component, arranged directly below the mixing component; the drug and the aqueous solvent can be separately packed in the storage box 4 and the liquid storage box 6, and the drug can be quantitatively loaded by the feeding component, and the drug can be preliminarily mixed by the mixing component, and then the drug and the aqueous solvent are fully oscillated and mixed by the oscillation component, so that the laser particle size analyzer 1 can analyze the drug.
[0083] like Figure 2 , Figure 3 , Figure 4 , Figure 6 As shown, the feeding assembly includes: a support rod 71, which is rotatably mounted on the inner wall of the bracket 3; a connecting plate 72, which is fixedly mounted on the top of the support rod 71; an adjusting plate 73, which is slidably mounted on the outer wall of the support rod 71; four openings 74, which are symmetrically arranged in groups of two on the top surfaces of the connecting plate 72 and the adjusting plate 73; two guide sleeves 75, which are respectively fixedly mounted on the inner walls of the two openings 74 on the connecting plate 72; two adjusting sleeves 76, which are fixedly mounted on the bottom surface of the adjusting plate 73 at the positions of the two openings 74, and the adjusting sleeves 76 are mounted on the corresponding guide sleeves 75; two covering plates 77, which are rotatably mounted on the bottom ends of the two adjusting sleeves 76 through a rotating shaft and a torsion spring; two support blocks 78, which are fixedly mounted in the radial direction of the two covering plates 77; a connecting sleeve 79, which is slidably mounted on the outer wall of the support rod 71, and the top of the connecting sleeve 79 is fixedly connected to the bottom surface of the adjusting plate 73; a guide ring 7 10, fixedly mounted on the bottom surface of the adjustment plate 73; the inclined surface 711, arranged on the outer wall of the guide ring 710; the adjusting mechanism, arranged on the outer wall of the connecting sleeve 79; the driving mechanism, arranged at the bottom end of the support rod 71; the support rod 71 can be rotated 180° by the driving mechanism. In the initial state, the opening 74 is located at a position corresponding to the feeding hopper 5. The position of the components is not shown in the figure for display. The medicine in the storage box 4 can enter the guide sleeve 75 and the adjusting sleeve 76 through the feeding hopper 5. As the connecting plate 72 and the adjusting plate 73 rotate 180°, the guide sleeve 75 and the adjusting sleeve 76 filled with the medicine can rotate, and the support block 78 can rotate along the bottom surface of the guide ring 710. At this time, the support block 78 can be located at the position of the inclined surface 711 on the guide ring 710. Under the action of the inclined surface 711, the torsion spring can drive the cover plate 77 to rotate to leak the bottom end of the adjusting sleeve 76.
[0084] like Figure 3 , Figure 4 As shown, the adjustment mechanism includes: a fixed frame 81, fixedly mounted on the inner wall of the pretreatment box 2; a lifting plate 82, slidably mounted on the inner wall of the fixed frame 81; a transmission rod 83, which penetrates the side wall of the pretreatment box 2; a transmission gear 84, fixedly mounted on the end of the transmission rod 83 located on the inner side of the pretreatment box 2; a knob 85, fixedly mounted on the end of the transmission rod 83 located on the outer side of the pretreatment box 2; a connecting frame 86, fixedly mounted on the top of the lifting plate 82, and the end of the connecting frame 86 away from the lifting plate 82 is fixedly connected to the connecting sleeve 79; a plurality of tooth grooves 87, which are distributed in a linear array up and down and are arranged on the side of the lifting plate 82 opposite to the transmission gear 84, and the tooth grooves 87 are meshed with the transmission gear 84; the knob 85 is rotated to drive the transmission gear 84 to rotate through the transmission rod 83, and the transmission gear 84 is meshed with the tooth grooves 87, so that the lifting plate 82 can be driven to slide along the fixed frame 81, thereby driving the connecting sleeve 79 and the adjustment plate 73 to slide along the support rod 71 through the connecting frame 86.
[0085] like Figure 5 As shown, the driving mechanism includes: a follower gear 91, fixedly mounted on the bottom end of the support rod 71; a mounting plate 92, fixedly mounted on the bottom surface of the follower gear 91; a driving motor 93, fixedly mounted on the bottom surface of the pretreatment box 2, and the output end of the driving motor 93 passes through the bottom surface of the pretreatment box 2; a semicircular plate 94, fixedly mounted on the output end of the driving motor 93, and arc grooves adapted to the semicircular plate 94 are provided at both ends of the mounting plate 92; a driving half gear 95, fixedly mounted on the top surface of the semicircular plate 94, and the driving half gear 95 and the follower gear 91 are connected to each other. Gear 91 is engaged; the driving motor 93 is turned on to drive the semicircular plate 94 and the driving half gear 95 to rotate. When the semicircular plate 94 rotates, it can rotate inside the arc groove on the mounting plate 92, so that the support rod 71 can load and unload materials stably, and when the semicircular plate 94 is separated from the mounting plate 92, the driving half gear 95 can be engaged with the follower gear 91 to drive the follower gear 91 to rotate. When the semicircular plate 94, the mounting plate 92, the follower gear 91 and the driving half gear 95 are used in conjunction with each other, the support rod 71 can rotate 180°.
[0086] like Figure 7 , Figure 8As shown, the mixing assembly includes: a support frame 101, fixedly mounted on the inner wall of the pretreatment box 2; a mixing bucket 102, threadedly mounted on the inner wall of the support frame 101, and a liquid adding pipe 12 is provided through the bottom surface of the liquid storage tank 6, and the end of the liquid adding pipe 12 away from the liquid storage tank 6 is located directly above the mixing bucket 102; a fixed gear ring 103, fixedly sleeved on the outer wall of the mixing bucket 102; an adjusting gear 104, rotatably mounted at a corner of the top surface of the support frame 101; a servo motor 105, fixedly mounted at a corner of the bottom surface of the support frame 101, and the output end of the servo motor 105 is fixedly connected to the adjusting gear 104; the mixing assembly also includes: a sealing ring 106, fixedly mounted on the inner wall of the discharge end of the mixing bucket 102; a fixed rod 107, fixedly mounted on the inner wall of the sealing ring 106; a sliding rod 108, which is provided through the fixed rod 1 07 is away from the end connected to the sealing ring 106; the sealing plug 109 is fixedly installed on the top of the sliding rod 108; the spring 1010 is mounted on the sliding rod 108 and is located below the fixed rod 107, and the two ends of the spring 1010 are fixedly connected to the sliding rod 108 and the fixed rod 107 respectively; the bottom plate 1011 is fixedly installed at the bottom end of the sliding rod 108; when the medicine is added to the mixing bucket 102, the liquid adding tube 12 can be opened to add the water solvent in the liquid storage tank 6 to the mixing bucket 102 for preliminary mixing with the medicine. After mixing, the servo motor 105 can be turned on to drive the adjusting gear 104 to rotate. The adjusting gear 104 is meshed with the fixed gear ring 103, so that the mixing bucket 102 can be driven to rotate. The mixing bucket 102 is threadedly connected to the support frame 101, so it can move in the vertical direction during rotation.
[0087] like Figure 7 , Fig. 9As shown, the oscillation assembly includes: a transmission column 111, which is rotatably mounted on the inner bottom wall of the pretreatment box 2; an oscillation motor 112, which is fixedly mounted on the bottom surface of the pretreatment box 2, and the output end of the oscillation motor 112 is fixedly connected to the bottom end of the transmission column 111; a connecting rod 113, which is fixedly mounted on the side position of the top surface of the transmission column 111; a mixing tank 114, which is fixedly mounted on the top of the connecting rod 113, and the mixing tank 114 is inclined; a discharge pipe 115, which is fixedly mounted on the bottom surface of the mixing tank 114, and the discharge pipe 115 is connected to the mixing tank 114, and a control valve is installed on the discharge pipe 115; a push rod 116, which is fixedly mounted on the inner side wall of the feeding end of the mixing tank 114; when the discharge end of the mixing bucket 102 enters the feeding end of the mixing tank 114, the push rod 116 inside the feeding end of the mixing tank 114 can lift the bottom plate 1011, the sliding rod 108 and the sealing plug 109, and the sealing plug After 109 is separated from the sealing ring 106, the mixture in the mixing bucket 102 can be added to the mixing tank 114. After the filling is completed, the servo motor 105 can be reversed to reset the mixing bucket 102 for reuse. After the mixture is added to the mixing tank 114, the oscillation motor 112 can be turned on to drive the transmission column 111 to rotate. Since the mixing tank 114 is inclined and the connecting rod 113 is arranged at the side position of the top of the transmission column 111, the transmission column 111 can drive the mixing tank 114 to rotate when it rotates, so as to achieve the oscillation of the mixing tank 114, so that the medicine can be fully mixed. After the mixing is completed, the feed pipe on the laser particle size analyzer 1 can be connected to the discharge pipe 115 on the mixing tank 114, so that the mixture in the mixing tank 114 is added to the laser particle size analyzer 1, and then the particle size analysis of the medicine can be completed by the laser particle size analyzer 1.
[0088] The specific working principle of the present invention is as follows:
[0089] First, the drug to be tested can be added to the storage box 4, and the drug can enter the hopper 5 under the action of gravity. Then, the position of the adjustment plate 73 can be adjusted according to the amount of drug to be tested. When adjusting, the knob 85 can be rotated to drive the transmission gear 84 to rotate through the transmission rod 83. The transmission gear 84 is engaged with the tooth groove 87, so that the lifting plate 82 can be driven to slide along the fixed frame 81, thereby driving the connecting sleeve 79 and the adjustment plate 73 to slide along the support rod 71 through the connecting frame 86, so that the overlapping part of the adjustment sleeve 76 and the guide sleeve 75 changes, thereby realizing the adjustment of the amount of drug loaded in the guide sleeve 75 and the adjustment sleeve 76;
[0090] After the adjustment is completed, the driving motor 93 can be turned on to drive the semicircular plate 94 and the driving half gear 95 to rotate. When the semicircular plate 94 rotates, it can rotate inside the arc groove on the mounting plate 92, so that the support rod 71 can load and unload materials stably, and when the semicircular plate 94 is separated from the mounting plate 92, the driving half gear 95 can mesh with the follower gear 91 to drive the follower gear 91 to rotate. When the semicircular plate 94, the mounting plate 92, the follower gear 91 and the driving half gear 95 are used in conjunction with each other, the lower support rod 71 can rotate 180°. In the initial state, the opening 74 is located at a position corresponding to the feeding hopper 5. The figure shows the components The position is not shown, the medicine in the storage box 4 can enter the guide sleeve 75 and the adjusting sleeve 76 through the feeding hopper 5, and as the connecting plate 72 and the adjusting plate 73 rotate 180 degrees, the guide sleeve 75 and the adjusting sleeve 76 filled with the medicine can be rotated to the top of the mixing bucket 102, and the support block 78 can be rotated along the bottom surface of the guide ring 710, at this time, the support block 78 can be located at the inclined surface 711 on the guide ring 710, and under the action of the inclined surface 711, the torsion spring can drive the cover plate 77 to rotate to leak the bottom end of the adjusting sleeve 76, and the medicine inside can fall into the mixing bucket 102;
[0091] When the medicine is added to the mixing bucket 102, the liquid adding pipe 12 can be opened so that the water solvent in the liquid storage tank 6 is added to the mixing bucket 102 for preliminary mixing with the medicine. After mixing, the servo motor 105 can be turned on to drive the adjusting gear 104 to rotate. The adjusting gear 104 is meshed with the fixed gear ring 103, so that the mixing bucket 102 can be driven to rotate. The mixing bucket 102 is threadedly connected to the support frame 101, so it can move in the vertical direction during rotation, so that the discharge end of the mixing bucket 102 enters the feeding end of the mixing tank 114. The top rod 116 inside the feeding end of the mixing tank 114 can lift the bottom plate 1011, the sliding rod 108 and the sealing plug 109. After the sealing plug 109 is separated from the sealing ring 106, the mixture in the mixing bucket 102 can be added to the mixing tank 114. After the filling is completed, the servo motor 105 can be reversed to reset the mixing bucket 102 so that it can be used again.
[0092] After the mixture is added to the mixing tank 114, the oscillation motor 112 can be turned on to drive the transmission column 111 to rotate. Since the mixing tank 114 is tilted and the connecting rod 113 is arranged at the side position of the top of the transmission column 111, the transmission column 111 can drive the mixing tank 114 to rotate when it rotates, so as to achieve the oscillation of the mixing tank 114, so that the medicine can be fully mixed. After the mixing is completed, the feed pipe on the laser particle size analyzer 1 can be connected with the discharge pipe 115 on the mixing tank 114, so that the mixture in the mixing tank 114 is added to the laser particle size analyzer 1, and then the particle size analysis of the medicine can be completed by the laser particle size analyzer 1. The above is only a preferred specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field within the technical scope disclosed by the present invention, according to the technical solution and its inventive concept of the present invention, is equivalently replaced or changed, which should be covered within the protection scope of the present invention.
Claims
1. A drug particle size analysis and detection device, characterized in that: include Laser particle size analyzer (1); A pretreatment box (2) is fixedly mounted on a side wall of the laser particle size analyzer (1); A bracket (3) fixedly mounted on the inner wall of the pretreatment box (2); A material storage box (4) is arranged on one side of the top surface of the pretreatment box (2); A feeding hopper (5) is fixedly mounted on the inner top wall of the pretreatment box (2), and the top end of the feeding hopper (5) is connected to the storage box (4); A liquid storage tank (6) is arranged on the other side of the top surface of the pretreatment tank (2); A feeding assembly, arranged on the support (3); A mixing assembly is arranged inside the pretreatment box (2) and at a position on one side of the bracket (3); The oscillating component is arranged directly below the mixing component.
2. The drug particle size analysis and detection device according to claim 1, characterized in that: The feeding assembly comprises A support rod (71) rotatably mounted on the inner side wall of the bracket (3); A connecting plate (72) fixedly mounted on the top end of the support rod (71); An adjusting plate (73) is slidably mounted on the outer wall of the support rod (71); Four openings (74) are symmetrically arranged in groups of two on the top surfaces of the connecting plate (72) and the adjusting plate (73); Two guide sleeves (75) are respectively fixedly mounted on the inner side walls of the two openings (74) on the connecting plate (72); Two adjustment sleeves (76) are fixedly mounted on the bottom surface of the adjustment plate (73) at the positions of the two openings (74), and the adjustment sleeves (76) are fitted with the corresponding guide sleeves (75); Two cover plates (77) are rotatably mounted on the bottom ends of the two adjusting sleeves (76) via a rotating shaft and a torsion spring; Two support blocks (78) are fixedly mounted in the radial direction of the two cover plates (77); A connecting sleeve (79) is slidably sleeved on the outer wall of the support rod (71), and the top end of the connecting sleeve (79) is fixedly connected to the bottom surface of the adjusting plate (73); A guide ring (710) fixedly mounted on the bottom surface of the adjustment plate (73); An inclined surface (711) is arranged on the outer wall of the guide ring (710); An adjustment mechanism, arranged on the outer wall of the connecting sleeve (79); The driving mechanism is arranged at the bottom end of the support rod (71).
3. The drug particle size analysis and detection device according to claim 2, characterized in that: The adjustment mechanism includes A fixing frame (81) fixedly mounted on the inner wall of the pretreatment box (2); A lifting plate (82) is slidably mounted on the inner side wall of the fixing frame (81) up and down; A transmission rod (83) is arranged to penetrate the side wall of the pretreatment box (2); A transmission gear (84) is fixedly mounted on one end of the transmission rod (83) located inside the pretreatment box (2); A knob (85) is fixedly mounted on one end of the transmission rod (83) located outside the pretreatment box (2); A connecting frame (86) is fixedly mounted on the top of the lifting plate (82), and one end of the connecting frame (86) away from the lifting plate (82) is fixedly connected to the connecting sleeve (79); A plurality of tooth grooves (87) are arranged in a linear array and arranged vertically on a side of the lifting plate (82) opposite to the transmission gear (84), and the tooth grooves (87) are meshed with the transmission gear (84).
4. The drug particle size analysis and detection device according to claim 3, characterized in that: The driving mechanism comprises A follower gear (91) is fixedly mounted on the bottom end of the support rod (71); A mounting plate (92) fixedly mounted on the bottom surface of the follower gear (91); A drive motor (93) is fixedly mounted on the bottom surface of the pretreatment box (2), and an output end of the drive motor (93) passes through the bottom surface of the pretreatment box (2); A semicircular plate (94) is fixedly mounted on the output end of the driving motor (93), and arc grooves adapted to the semicircular plate (94) are formed at both ends of the mounting plate (92); The driving half gear (95) is fixedly mounted on the top surface of the semicircular plate (94), and the driving half gear (95) is meshed with the follower gear (91).
5. The drug particle size analysis and detection device according to claim 4, characterized in that: The mixing assembly comprises A support frame (101) fixedly mounted on the inner wall of the pretreatment box (2); A mixing bucket (102) threadably mounted on the inner wall of the support frame (101); A fixed gear ring (103) fixedly mounted on the outer wall of the mixing bucket (102); An adjusting gear (104) is rotatably mounted on a corner of the top surface of the supporting frame (101); The servo motor (105) is fixedly mounted at a corner of the bottom surface of the support frame (101), and the output end of the servo motor (105) is fixedly connected to the adjusting gear (104).
6. The drug particle size analysis and detection device according to claim 5, characterized in that: The mixing assembly also includes A sealing ring (106) is fixedly mounted on the inner wall of the discharge end of the mixing bucket (102); A fixing rod (107) fixedly mounted on the inner wall of the sealing ring (106); A sliding rod (108) is provided through the end of the fixing rod (107) away from the end connected with the sealing ring (106); A sealing plug (109) is fixedly mounted on the top of the sliding rod (108); A spring (1010) is sleeved on the sliding rod (108) and is located below the fixed rod (107), and two ends of the spring (1010) are respectively fixedly connected to the sliding rod (108) and the fixed rod (107); The bottom plate (1011) is fixedly mounted on the bottom end of the sliding rod (108).
7. The drug particle size analysis and detection device according to claim 6, characterized in that: The oscillating component includes A transmission column (111) rotatably mounted on the inner bottom wall of the pretreatment box (2); An oscillating motor (112) is fixedly mounted on the bottom surface of the pretreatment box (2), and an output end of the oscillating motor (112) is fixedly connected to the bottom end of the transmission column (111); A connecting rod (113) is fixedly mounted on a side edge of the top surface of the transmission column (111); A mixing tank (114) is fixedly mounted on the top end of the connecting rod (113); A discharge pipe (115) is fixedly mounted on the bottom surface of the mixing tank (114), and the discharge pipe (115) is in communication with the mixing tank (114); A push rod (116) is fixedly mounted on the inner wall of the feeding end of the mixing tank (114).
8. The drug particle size analysis and detection device according to claim 7, characterized in that: A liquid adding pipe (12) is provided through the bottom surface of the liquid storage tank (6), and one end of the liquid adding pipe (12) away from the liquid storage tank (6) is located directly above the mixing bucket (102).
9. The drug particle size analysis and detection device according to claim 8, characterized in that: The mixing tank (114) is arranged in an inclined manner, and a control valve is installed on the discharge pipe (115).
10. The drug particle size analysis and detection device according to claim 9, characterized in that: An operation port (13) is provided on the side of the pretreatment box (2).
