Continuous reaction purification method for preparing amino acid surfactant

Abstract

The invention discloses a continuous reaction purification method for preparing an amino acid surfactant, and belongs to the technical field of preparation of amino acid surfactants. Comprising the following steps: step 1, raw material preparation, step 2, continuous reaction, step 3, separation, step 4, continuous purification, and step 5, collection and packaging: collecting the continuously purified amino acid surfactant, and packaging the collected product to prevent the product from being degraded. According to the method, through continuous mixing reaction, centrifugal separation and purification, the production efficiency can be improved, unreacted substances and impurities can be stably and effectively removed, and it is ensured that a high-purity amino acid surfactant product is produced.

Description

Technical Field

[0001] The invention belongs to the technical field of amino acid surfactant preparation, and in particular relates to a continuous reaction purification method for the preparation of amino acid surfactant. Background Art

[0002] With the rapid development of the chemical industry, amino acid surfactants, as an important surfactant, have attracted much attention due to their unique properties and wide application fields. Amino acid surfactants not only have excellent surface activity and emulsification properties, but also have good biocompatibility and environmental friendliness, so they have broad application prospects in high-end cosmetics, biomedicine, green food and other fields.

[0003] However, most traditional preparation processes use intermittent production methods, which have the disadvantage of low production efficiency and are difficult to meet the needs of large-scale production. Summary of the invention

[0004] The object of the present invention is to provide a continuous reaction and purification method for preparing an amino acid surfactant, which is used to solve the technical problem that most of the continuous reaction and purification methods for preparing an amino acid surfactant in the prior art adopt an intermittent production method, which has the disadvantage of low production efficiency and is difficult to meet the needs of large-scale production.

[0005] In order to achieve the above object, the present invention adopts the following technical solutions: The invention discloses a continuous reaction purification method for preparing an amino acid surfactant, comprising the following steps: step 1, raw material preparation: preparing hydrophilic amino acids, natural fatty acids, catalysts and solvents for preparing amino acid surfactants, wherein the hydrophilic amino acid is selected from glycine, the natural fatty acid is selected from coconut oil fatty acid, the catalyst is selected from toluenesulfonic acid, and the solvent is selected from anhydrous ethanol; step 2, continuous reaction: adding the hydrophilic amino acid, natural fatty acid, catalyst and solvent into a mixing barrel in a preparation device, and mixing the hydrophilic amino acid, natural fatty acid, catalyst and solvent through a mixing mechanism in the preparation device, so that the hydrophilic amino acid, natural fatty acid, catalyst and solvent fully react. The molar ratio of hydrophilic amino acid, natural fatty acid, catalyst and solvent is 1: (1.05-1.2): (0.05-0.07): (10-15); Step 3, separation: open the valve in the preparation device to introduce the reacted mixture in the mixing cylinder into the centrifugal mechanism in the preparation device, and separate the unreacted raw materials and by-products through the centrifugal mechanism to obtain a crude product; Step 4, continuous purification: convey the crude product to a continuous crystallizer for further purification to separate the residual unreacted products and impurities; Step 5, collection and packaging: collect the amino acid surfactant after continuous purification, and then package the collected product to prevent product degradation; The preparation device comprises: a mixing drum, a feeding pipe and a connecting pipe are installed on the top of the mixing drum, and a discharge pipe and a plurality of support plates are installed on the bottom of the mixing drum; a heating drum is installed on the mixing drum; a mixing mechanism is used to stir the materials in the mixing drum; a centrifugal mechanism is located directly below the mixing drum and is connected to the discharge pipe, and comprises: a driving assembly; a linkage assembly is used to drive the mixing mechanism to operate; The centrifugal mechanism further comprises: a fixed cylinder fixedly connected to the lower ends of the plurality of support plates; a guide ring mounted on the inner top surface of the fixed cylinder; a centrifugal cylinder rotatably connected to the fixed cylinder and the guide ring; a slag discharge pipe fixedly connected to the centrifugal cylinder, penetrating the bottom surface of the fixed cylinder and rotatably connected to the fixed cylinder; a plugging member detachably connected to the slag discharge pipe; a gear ring fixedly sleeved on the slag discharge pipe; and a liquid discharge pipe mounted on the fixed cylinder; The linkage assembly includes: a reducer mounted on the side of the fixed cylinder; a vertical rod connected to the output end of the reducer; two first sprockets, both fixedly sleeved on the vertical rod; two chains, the chains sleeved on the first sprocket and the second sprocket; a cam mounted on the upper end of the vertical rod; and a driven gear connected to the input end of the reducer; The driving assembly comprises: a motor mounted on the bottom surface of the fixed cylinder; a driving gear fixedly connected to the power output shaft of the motor and meshingly connected to the driven gear and the gear ring.

[0006] Preferably, the preparation device further comprises: a top cover detachably connected to the feed pipe; and a valve installed on the discharge pipe.

[0007] Preferably, the mixing mechanism includes: a shaft rod, which passes through the top surface of the mixing barrel and is rotatably connected to the mixing barrel; a plurality of stirring plates, all located in the mixing barrel and fixedly connected to the shaft rod; a first gear, which is fixedly connected to the upper end of the shaft rod; a guide block, which is installed on the top surface of the mixing barrel; a rack, which is slidably connected to the guide block, meshingly connected to the first gear, and in contact with the cam; a movable plate, which is fixedly connected to the rack; a fixed plate, which is fixedly connected to the top surface of the mixing barrel; and a plurality of springs, which are installed between the movable plate and the fixed plate.

[0008] Preferably, the centrifugal mechanism also includes a cleaning assembly, which includes: a cleaning ring, which is sleeved on the centrifugal cylinder and has a cleaning brush installed on its inner wall, and the cleaning brush is in contact with the outer surface of the centrifugal cylinder; two reciprocating screw nuts, both of which are installed on the cleaning ring; two reciprocating screws, both of which penetrate the top surface of the fixed cylinder and are rotatably connected to the fixed cylinder, and respectively penetrate the two reciprocating screw nuts; two second sprockets, respectively fixedly sleeved on the parts of the reciprocating screw located outside the fixed cylinder.

[0009] Preferably, the preparation device also includes a control system, which includes: a data acquisition module, which is used to collect comprehensive data information of the preparation device, wherein the comprehensive data information includes weight data of the mixture, viscosity data of the mixture, vibration intensity data of the centrifuge cylinder and resistance data of the centrifuge cylinder; a data analysis module, which receives a threshold range of a preset power influence coefficient set by a user, generates a power influence coefficient according to the comprehensive data information, and then compares the power influence coefficient with the threshold range of the preset power influence coefficient to determine and generate a corresponding power level; a data acquisition module, which is used to collect a historical training data set for the preparation device, the historical training data set includes centrifugal comprehensive influence data and centrifugal time; a time prediction module, which trains a machine learning model for predicting centrifugal time based on the historical training data set, collects real-time centrifugal comprehensive influence data, and inputs it into the trained machine learning model to predict the centrifugal time.

[0010] Preferably, the power influence coefficient is generated as follows: ; In the formula, is the power influence coefficient, is the weight data of the mixture, is the viscosity data of the mixture, is the vibration intensity data of the centrifuge cylinder, is the resistance data of the centrifugal cylinder; The power level is generated as follows: the power level includes level 1 power, level 2 power and level 3 power; the threshold range of the preset power influence coefficient is , , < ;like , at this time, the data analysis module generates the first-level power; if , at this time, the data analysis module generates secondary power; if ,At this time, the data analysis module generates level 3 power.

[0011] In summary, due to the adoption of the above technical solution, the beneficial effects of the present invention are: 1. This method can improve production efficiency through continuous mixing reaction, centrifugal separation and purification, and can also stably and effectively remove unreacted products and impurities to ensure the production of high-purity amino acid surfactant products.

[0012] 2. The mixing mechanism of the present invention is provided with a shaft, a stirring plate, a first gear, a rack, a movable plate, a fixed plate and a spring. When in use, it can effectively break the vortex flow of the material in the mixing barrel by alternating clockwise and counterclockwise stirring, reduce dead corners and unstirred areas, improve the mixing and reaction efficiency, and reduce the generation of bubbles, thereby further improving the quality and efficiency of the reaction.

[0013] 3. The drive assembly of the present invention is provided with a motor and a driving gear. When the motor is running, it will drive the driving gear to rotate, and then link the reducer, vertical rod, gear and sprocket to realize the integrated drive of mixing, centrifugal and cleaning functions. This design realizes the unified drive of multiple functional modules, saving equipment space and cost.

[0014] 4. The preparation device in the present invention is provided with a control system. The control system collects comprehensive data information of the preparation device through a data acquisition module, which provides an accurate basis for adjusting the motor power. The data analysis module of the control system generates a power influence coefficient according to the collected comprehensive data information, and judges and generates a corresponding power level, thereby realizing dynamic adjustment of the motor power to meet the needs under different working conditions, avoiding unnecessary energy waste, and improving energy utilization efficiency; the control system also predicts the centrifugal time through a time prediction module, thereby controlling the running time of the motor and improving the efficiency of the centrifugal operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0016] Figure 1 The process flow chart of the continuous reaction purification method for preparing the amino acid surfactant of the present invention; Figure 2 A three-dimensional diagram of the preparation device of the present invention; Figure 3 It is a schematic diagram of the internal structure of the mixing cylinder and the fixed cylinder in the present invention; Figure 4 It is a schematic diagram of the internal structure of the fixed cylinder in the present invention; Figure 5 is a three-dimensional diagram of the centrifugal mechanism of the present invention; Figure 6 It is a schematic diagram of the assembly structure of the cleaning component, the linkage component and the driving component in the present invention; Figure 7It is a schematic diagram of the assembly structure of the mixing cylinder, the discharge pipe and the valve in the present invention; Figure 8 is a three-dimensional diagram of the blocking member in the present invention; Fig. 9 A three-dimensional diagram of a guide block in the present invention; Fig.10 It is a module diagram of the control system in the present invention; Figure numerals: 100, mixing cylinder; 101, heating cylinder; 102, feeding pipe; 103, top cover; 104, connecting pipe; 105, discharge pipe; 106, valve; 107, support plate; 110, mixing mechanism; 111, shaft; 112, stirring plate; 113, first gear; 114, guide block; 115, rack; 116, movable plate; 117, fixed plate; 118, spring; 200, centrifugal mechanism; 201, fixed cylinder; 202, guide ring; 203, centrifugal cylinder; 204, slag discharge pipe ; 205, blocking member; 2051, sealing cover; 2052, connecting rod; 2053, blocking plate; 206, gear ring; 207, drain pipe; 210, cleaning assembly; 211, cleaning ring; 212, reciprocating screw nut; 213, reciprocating screw; 214, second sprocket; 220, linkage assembly; 221, reducer; 222, vertical rod; 223, first sprocket; 224, chain; 225, cam; 226, driven gear; 230, driving assembly; 231, motor; 232, driving gear. DETAILED DESCRIPTION

[0017] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0018] Example 1: Figure 1-Figure 3 As shown, the continuous reaction purification method for preparing an amino acid surfactant comprises the following steps: Step 1, raw material preparation: prepare hydrophilic amino acid, natural fatty acid, catalyst and solvent for preparing amino acid surfactant; wherein, the hydrophilic amino acid is glycine, the natural fatty acid is coconut oil fatty acid, the catalyst is toluenesulfonic acid, and the solvent is anhydrous ethanol; Step 2, continuous reaction: connect the connecting tube 104 in the preparation device to the thin film evaporator, remove the top cover 103 on the feed pipe 102, add the hydrophilic amino acid, natural fatty acid, catalyst and solvent into the mixing barrel 100 in the preparation device through the feed pipe 102, and then thread the top cover 103 to the feed pipe 102; start the heating barrel 101 in the preparation device to heat the mixing barrel 100 so that the internal temperature of the mixing barrel 100 reaches 150° C., and then mix the hydrophilic amino acid, natural fatty acid, catalyst and solvent through the mixing mechanism 110 in the preparation device to ensure that the hydrophilic amino acid, natural fatty acid, catalyst and solvent react fully; during the reaction, the thin film evaporator will remove the water generated by the reaction in real time; wherein the molar ratio of the hydrophilic amino acid, natural fatty acid, catalyst and solvent is 1:1.2:0.07:15; Step 3, separation: opening the valve 106 in the preparation device, introducing the reacted mixture in the mixing cylinder 100 into the centrifugal mechanism 200 in the preparation device, separating the unreacted raw materials and by-products by the centrifugal mechanism 200 to obtain a crude product; Step 4: Continuous purification: The crude product is conveyed to a continuous crystallizer for further purification to separate the remaining unreacted products and impurities; Step 5: Collection and packaging: Collect the amino acid surfactants after continuous purification, and then package the collected products to prevent product degradation.

[0019] The method can improve production efficiency through continuous mixing reaction, centrifugal separation and purification, and can also stably and effectively remove unreacted substances and impurities, thereby ensuring the production of high-purity amino acid surfactant products.

[0020] Example 2: Figure 1-Figure 3 As shown, when other parts are the same as those in the embodiment, the difference between this embodiment and the embodiment is that the preparation device includes a mixing cylinder 100, a heating cylinder 101, a mixing mechanism 110 and a centrifugal mechanism 200.

[0021] A feed pipe 102 and a connecting pipe 104 are installed on the top of the mixing barrel 100, and a discharge pipe 105 and a plurality of support plates 107 are installed at the bottom of the mixing barrel 100; the heating barrel 101 is installed on the heating barrel 101, and the heating barrel 101 is used to heat the mixing barrel 100, and then heat the material located in the mixing barrel 100.

[0022] The mixing mechanism 110 is used to stir the material in the mixing drum 100; the centrifugal mechanism 200 is located directly below the mixing drum 100, and the centrifugal mechanism 200 is connected to the discharge pipe 105. The centrifugal mechanism 200 includes a driving assembly 230 and a linkage assembly 220, and the linkage assembly 220 is used to drive the mixing mechanism 110 to operate.

[0023] Specifically, the connecting tube 104 is connected to an external thin film evaporator, and the hydrophilic amino acid, natural fatty acid, catalyst and solvent are added into the mixing barrel 100 through the feeding tube 102, and then the connecting tube 104 is sealed. Then, the heating barrel 101 is started to heat the mixing barrel 100, thereby heating the hydrophilic amino acid, natural fatty acid, catalyst and solvent in the mixing barrel 100.

[0024] Then, by starting the driving component 230, the power of the driving component 230 is transmitted to the mixing mechanism 110 through the linkage component 220, so that the mixing mechanism 110 stirs the hydrophilic amino acids, natural fatty acids, catalysts and solvents in the mixing barrel 100, so that the hydrophilic amino acids, natural fatty acids, catalysts and solvents are heated evenly. In the stirring process, the hydrophilic amino acids, natural fatty acids, catalysts and solvents can be mixed evenly, which is beneficial to accelerate the reaction efficiency of the hydrophilic amino acids, natural fatty acids, catalysts and solvents.

[0025] like Figure 3 and Figure 7 As shown, the preparation device further includes a top cover 103 and a valve 106. The top cover 103 is detachably connected to the feed pipe 102; the valve 106 is installed on the discharge pipe 105.

[0026] Specifically, when it is necessary to add materials into the mixing drum 100, the top cover 103 is separated from the feeding pipe 102 to facilitate adding materials into the mixing drum 100 through the feeding pipe 102. After the adding is completed, the top cover 103 is separated from the feeding pipe 102 to prevent the hot air in the mixing drum 100 from flowing out through the feeding pipe 102. When it is necessary to transport the reacted mixture in the mixing drum 100 into the centrifugal mechanism 200, the valve 106 can be opened to allow the reacted mixture to enter the centrifugal mechanism 200 through the discharge pipe 105.

[0027] like Figure 3 As shown, the mixing mechanism 110 includes a shaft 111 , a plurality of stirring plates 112 , a first gear 113 , a guide block 114 , a rack 115 , a movable plate 116 , a fixed plate 117 and a plurality of springs 118 .

[0028] The shaft 111 passes through the top surface of the mixing drum 100 and is rotatably connected to the mixing drum 100; multiple stirring plates 112 are located in the mixing drum 100, and the multiple stirring plates 112 are fixedly connected to the shaft 111; the first gear 113 is fixedly connected to the upper end of the shaft 111; the guide block 114 is installed on the top surface of the mixing drum 100; the bottom plate of the rack 115 is provided with a sliding groove matching the guide block 114, the rack 115 is slidably connected to the guide block 114, and the rack 115 is meshed with the first gear 113; the movable plate 116 is fixedly connected to the rack 115; the fixed plate 117 is fixedly connected to the top surface of the mixing drum 100; and multiple springs 118 are installed between the movable plate 116 and the fixed plate 117.

[0029] Specifically, by pushing the rack 115 toward the fixed plate 117, the spring 118 will be compressed, and the first gear 113 meshing with the rack 115 will rotate, and the rotating first gear 113 will drive the shaft 111 to rotate, and then drive the multiple stirring plates 112 to rotate, and then stir the items in the mixing drum 100. At this time, if the rack 115 is pushed, the spring 118 will push the movable plate 116 to move under the influence of the rebound force of the spring 118, and then push the rack 115 to move, and then the first gear 113, the shaft 111 and the stirring rod will rotate.

[0030] If the rack 115 is intermittently pushed to move toward the fixing plate 117 , the first gear 113 will be intermittently rotated clockwise and counterclockwise, thereby causing the shaft 111 and the stirring plate 112 to be intermittently rotated clockwise and counterclockwise.

[0031] like Figure 2-Figure 4 As shown, the centrifugal mechanism 200 further includes a fixed cylinder 201 , a guide ring 202 , a centrifugal cylinder 203 , a slag discharge pipe 204 , a blocking member 205 , a gear ring 206 and a liquid discharge pipe 207 . The fixed cylinder 201 is fixedly connected to the lower ends of multiple support plates 107; the guide ring 202 is installed on the inner top surface of the fixed cylinder 201; a plurality of through holes are opened on the centrifugal cylinder 203, and the centrifugal cylinder 203 is rotatably connected to the fixed cylinder 201 and the guide ring 202; the slag discharge pipe 204 is fixedly connected to the centrifugal cylinder 203, and the slag discharge pipe 204 passes through the bottom surface of the fixed cylinder 201 and is rotatably connected to the fixed cylinder 201; the sealing member 205 is detachably connected to the slag discharge pipe 204; the sealing member 205 includes a sealing cover 2051, a connecting rod 2052 and a sealing plate 2053, the sealing cover 2051 is threadedly connected to the slag discharge pipe 204, the connecting rod 2052 is installed on the inner bottom surface of the sealing cover 2051, and the sealing plate 2053 is installed at the upper end of the connecting rod 2052, the sealing plate 2053 is circular, and the outer diameter of the sealing plate 2053 is the same as the inner diameter of the slag discharge pipe 204. The gear ring 206 is fixedly sleeved on the slag discharge pipe 204 ; the liquid discharge pipe 207 is installed on the fixed cylinder 201 .

[0032] Specifically, the centrifugal drum 203 receives the reacted mixture discharged from the discharge pipe 105, and then drives the discharge pipe 204 to rotate by rotating the gear ring 206, thereby driving the centrifugal drum 203 to rotate, and the rotating centrifugal drum 203 centrifugally processes the items inside it.

[0033] After the centrifugal operation is completed, the sealing cover 2051 is rotated to separate the sealing cover 2051 from the slag discharge pipe 204, and then the blocking plate 2053 and the connecting rod 2052 are taken out from the slag discharge pipe 204, so as to facilitate the removal of the objects located in the centrifugal cylinder 203.

[0034] like Figure 4 As shown, the centrifugal mechanism 200 further includes a cleaning assembly 210 , and the cleaning assembly 210 includes a cleaning ring 211 , two reciprocating screw nuts 212 , two reciprocating screws 213 and two second sprockets 214 .

[0035] The cleaning ring 211 is sleeved on the centrifugal cylinder 203, and a cleaning brush is installed on the inner wall of the cleaning ring 211, and the cleaning brush is in contact with the outer surface of the centrifugal cylinder 203; the two reciprocating screw nuts 212 are both installed on the cleaning ring 211; the two reciprocating screws 213 are both installed on the top surface of the fixed cylinder 201 and are rotatably connected to the fixed cylinder 201, and the two reciprocating screws 213 are respectively inserted into the two reciprocating screw nuts 212; the two second sprockets 214 are respectively fixedly sleeved on the parts of the reciprocating screws 213 located outside the fixed cylinder 201.

[0036] Specifically, when the two reciprocating screws 213 rotate simultaneously, the two reciprocating screw nuts 212 will move up and down along the screws, thereby driving the cleaning ring 211 to move up and down, and the cleaning brush will clean the outer surface of the centrifugal cylinder 203, thereby preventing debris from clogging the centrifugal cylinder 203 and affecting the centrifugal efficiency.

[0037] like Figure 4 and Figure 6 As shown, the linkage assembly 220 includes a reducer 221 , a vertical rod 222 , two first sprocket wheels 223 , two chains 224 , a cam 225 and a driven gear 226 .

[0038] The reducer 221 is installed on the side of the fixed cylinder 201; the vertical rod 222 is connected to the output end of the reducer 221, and the vertical rod 222 is rotatably connected to the mixing cylinder 100. The two first sprockets 223 are fixedly sleeved on the vertical rod 222; the two chains 224 are sleeved on the first sprocket 223 and the second sprocket 214; the cam 225 is installed on the upper end of the vertical rod 222, and the cam 225 is in contact with the rack 115; the driven gear 226 is connected to the input end of the reducer 221.

[0039] Specifically, when the driven gear 226 rotates, it will drive the vertical rod 222 to rotate through the reducer 221, and then drive the two first sprockets 223 and the cam 225 to rotate. When the two first sprockets 223 rotate, they will drive the two second sprockets 214 to rotate respectively through the two chains 224, and then drive the two reciprocating screws 213 to rotate; and when the cam 225 rotates, it will drive the rack 115 to move, and with the cooperation of the rotating cam 225 and the spring 118, the rack 115 will move back and forth horizontally.

[0040] like Figure 5 As shown, the driving assembly 230 includes a motor 231 and a driving gear 232. The motor 231 is mounted on the bottom surface of the fixed cylinder 201. The driving gear 232 is fixedly connected to the power output shaft of the motor 231, and the driving gear 232 is meshedly connected with the driven gear 226 and the gear ring 206.

[0041] Specifically, when the motor 231 rotates, the power output shaft of the motor 231 drives the driving gear 232 to rotate, and then meshes and drives the driven gear 226 and the gear ring 206 to rotate.

[0042] Working principle: When it is necessary to react hydrophilic amino acids, natural fatty acids, catalysts and solvents, and to centrifuge the mixture after the reaction, the connecting tube 104 is connected to the external thin film evaporator, the discharge pipe 207 is connected to the external continuous crystallizer, and then the top cover 103 is separated from the connecting tube 104, and the hydrophilic amino acids, natural fatty acids, catalysts and solvents are added into the mixing cylinder 100 through the feed pipe 102, and then the connecting tube 104 is sealed with the top cover 103.

[0043] Then, the heating cylinder 101 is started to heat the mixing cylinder 100 , thereby heating the hydrophilic amino acid, natural fatty acid, catalyst and solvent in the mixing cylinder 100 .

[0044] Then, by starting the motor 231 to rotate, the power output shaft of the motor 231 will drive the driving gear 232 to rotate, and then mesh with the driven gear 226 to rotate, and then drive the vertical rod 222 to rotate through the reducer 221, and then drive the cam 225 to rotate. The rotating cam 225 will drive the push rack 115 to move, and with the cooperation of the cam 225 and the spring 118, the rack 115 will move back and forth horizontally. When the rack 115 moves, it will drive the first gear 113 to rotate, and then drive the shaft 111 and the stirring plate 112 to rotate, so that the stirring plate 112 mixes the hydrophilic amino acids, natural fatty acids, catalysts and solvents in the mixing barrel 100, which is beneficial to accelerate the reaction efficiency of the hydrophilic amino acids, natural fatty acids, catalysts and solvents.

[0045] When the rack 115 reciprocates horizontally, the first gear 113 rotates intermittently clockwise and counterclockwise, thereby causing the shaft 111 and the stirring plate 112 to rotate intermittently clockwise and counterclockwise, thereby further improving the mixing efficiency and the reaction efficiency.

[0046] Compared with the method of continuous stirring in one direction, the method of alternating stirring (the stirring plate 112 rotates alternately clockwise and counterclockwise) has the following advantages: first, the vortex flow of the hydrophilic amino acid, natural fatty acid, catalyst and solvent in the mixing barrel 100 can be broken by rotating the stirring blades alternately clockwise and counterclockwise, thereby avoiding dead corners and unstirred areas caused by the hydrophilic amino acid, natural fatty acid, catalyst and solvent flowing in a fixed direction; Second, alternating stirring can more effectively break the laminar structure between hydrophilic amino acids, natural fatty acids, catalysts and solvents by changing the stirring direction, speeding up the mixing speed and thus speeding up the reaction efficiency; Third, since the stirring direction of the alternating stirring is constantly changed, the bubbles in the hydrophilic amino acid, natural fatty acid, catalyst and solvent in the mixing barrel 100 can be dispersed, and the generation of bubbles can be reduced.

[0047] As the reaction proceeds, the thin film evaporator removes the water produced in real time.

[0048] After the reaction is completed, the valve 106 is opened to allow the reaction mixture in the mixing drum 100 to enter the centrifugal drum 203 through the discharge pipe 105. Then, the motor 231 is started to drive the driving gear 232 to rotate through the power output shaft of the motor 231, thereby engaging and driving the gear ring 206 to rotate, thereby driving the discharge pipe 204 to rotate, and thereby driving the centrifugal drum 203 to rotate. The rotating centrifugal drum 203 will centrifuge the reaction mixture inside it.

[0049] When the driving gear 232 rotates, it will drive the vertical rod 222 to rotate through the reducer 221, and then drive the two first sprockets 223 to rotate, and then drive the two second sprockets 214 to rotate through the two chains 224, and then drive the two reciprocating screws 213 to rotate. When the two reciprocating screws 213 rotate at the same time, the two reciprocating screw nuts 212 will move back and forth up and down along the screws, and then drive the cleaning ring 211 to move back and forth up and down, so that the cleaning brush cleans the outer surface of the centrifugal cylinder 203, thereby preventing debris from clogging the centrifugal cylinder 203 and affecting the centrifugal efficiency.

[0050] After the centrifugation operation is completed, the crude product after centrifugation is transported to the continuous crystallizer through the drain pipe 207 for further purification to separate the remaining unreacted substances and impurities. Finally, the amino acid surfactant after continuous purification is collected and packaged.

[0051] Example 3: Figure 2-Figure 6 and Fig.10 As shown, when other parts are the same as those in Example 1, the difference between this embodiment and Example 2 is that the preparation device also includes a control system, and the control system includes: a data acquisition module, a data analysis module, a data acquisition module and a time prediction module, and the modules are connected by wired / wireless means to realize data transmission.

[0052] The data collection module is used to collect comprehensive data information of the preparation device, wherein the comprehensive data information includes weight data of the mixture, viscosity data of the mixture, vibration intensity data of the centrifugal cylinder 203 and resistance data of the centrifugal cylinder 203 .

[0053] Specifically, the weight data of the mixture refers to the weight of the mixture after the reaction in the centrifugal cylinder 203, and the weight of the mixture can be measured by a weighing sensor; The viscosity data of the mixture refers to the viscosity of the mixture after the reaction in the centrifugal cylinder 203. The viscosity of the mixture can be obtained by real-time monitoring through an online viscosity sensor; The vibration intensity data of the centrifugal drum 203 refers to the vibration generated when the centrifugal drum 203 rotates. The vibration intensity data of the centrifugal drum 203 can be obtained by a vibration sensor; The resistance data of the centrifugal cylinder 203 refers to the friction resistance of the fixed cylinder 201, the guide ring 202 and the cleaning ring 211 when the centrifugal cylinder 203 rotates. The resistance data of the centrifugal cylinder 203 can be measured and obtained by a torque sensor or a friction force sensor.

[0054] The data analysis module is used to receive the threshold range of the preset power impact coefficient set by the user, and the data analysis module generates the power impact coefficient according to the comprehensive data information, and then compares the power impact coefficient with the threshold range of the preset power impact coefficient, and finally, determines and generates the corresponding power level; The power influence factor is generated as follows: ; In the formula, is the power influence coefficient, is the weight data of the mixture, is the viscosity data of the mixture, is the vibration intensity data of the centrifugal cylinder 203, is the resistance data of the centrifugal cylinder 203, , , and are all weight coefficients, which are determined by technicians in this field according to specific application requirements. , , and All are greater than 0; The higher the weight of the mixture in the centrifugal cylinder 203, the greater the moment of inertia of the centrifugal cylinder 203. During the centrifugation process, the power of the motor 231 needs to be increased to meet the requirements of starting, accelerating and maintaining the stable rotation of the centrifugal cylinder 203, and vice versa. The higher the viscosity of the mixture in the centrifuge barrel 203, the greater the friction between the molecules inside the mixture. During the centrifugal separation process, the material with high viscosity also has greater resistance to the wall of the centrifuge barrel 203, thereby increasing the resistance of the centrifuge barrel 203 during rotation. Therefore, it is necessary to increase the power of the motor 231 to maintain the rotation speed of the centrifuge barrel 203, and vice versa.

[0055] The vibration of the centrifugal drum 203 is caused by the imbalance of materials in the centrifugal drum 203 or the wear of equipment parts. When the centrifugal drum 203 vibrates more, more additional resistance and instability are generated, and the power of the motor 231 needs to be increased to maintain a stable speed, and vice versa.

[0056] The greater the resistance of the centrifugal drum 203 is, the more resistance the centrifugal drum 203 needs to overcome when rotating, and the motor 231 needs to increase the power to maintain the rotation speed of the centrifugal drum 203, and vice versa.

[0057] It should be noted that the formulas involved in the above-mentioned are all calculated by removing dimensions and taking numerical values. They are a formula that is closest to the actual situation obtained by collecting a large amount of data and performing software simulation. The weight coefficients in the formulas and the various preset thresholds in the analysis process are set by technical personnel in this field according to actual conditions or obtained by simulating a large amount of data; the size of the weight coefficient is to quantify each parameter to obtain a specific value for subsequent comparison. The size of the weight coefficient depends on the amount of sample data and the corresponding processing coefficients initially set by technical personnel in this field for each group of sample data; as long as it does not affect the proportional relationship between the parameters and the quantized values.

[0058] The power levels are generated as follows: The power levels include primary power, secondary power and tertiary power, wherein the primary power, secondary power and tertiary power increase in sequence, and the primary power, secondary power and tertiary power are all the power of the motor 231; The threshold range of the preset power influence coefficient is , , < ; like ,At this time, the data analysis module generates the first-level power; like ,At this time, the data analysis module generates secondary power; like ,At this time, the data analysis module generates level 3 power.

[0059] in, and It is determined by those skilled in the art according to specific application requirements.

[0060] Exemplarily, the power of motor 231 corresponding to level 1 power, level 2 power and level 3 power is 10kW, 20kW and 30kW respectively; the power of motor 231 can also be customized according to specific circumstances; the power of motor 231 is controlled according to the corresponding power level.

[0061] The data acquisition module is used to collect a historical training data set of the preparation device, and the historical training data set includes centrifugal comprehensive impact data and centrifugal duration; wherein the centrifugal comprehensive impact data includes comprehensive data information and the power of the motor 231, and the power data of the motor 231 can be measured and obtained by a power meter; The centrifugation time refers to the time required from the start of centrifugation of the mixture in the centrifuge barrel 203 to the completion of the centrifugation. The centrifugation time can be obtained by a timer.

[0062] The time prediction module trains a machine learning model for predicting centrifugal duration based on a historical training data set, collects real-time centrifugal comprehensive impact data, and inputs it into the trained machine learning model to predict the centrifugal duration; The training method of the machine learning model for predicting centrifugal duration includes: Convert the collected centrifugal comprehensive impact data into a corresponding set of feature vectors; Each group of feature vectors is used as the input of the machine learning model. The machine learning model takes the centrifugal time corresponding to each group of centrifugal comprehensive impact data as output, takes the centrifugal time actually corresponding to each group of centrifugal comprehensive impact data as the prediction target, and takes minimizing the loss function value of the machine learning model as the training target; training is stopped when the loss function value of the machine learning model is less than or equal to the preset target loss value.

[0063] The machine learning model may be one of the models such as SVM regression, random forest regression or neural network regression.

[0064] The loss function value of the machine learning model is the mean square error; Mean square error is one of the commonly used loss functions. Minimization is used as the goal to train the model so that the machine learning model better fits the data, thereby improving the performance and accuracy of the model; In the loss function is the loss function value of the machine learning model, x is the feature vector group number; m is the number of feature vector groups; is the centrifugal duration predicted by the x-th group of feature vectors, is the actual centrifugal duration corresponding to the xth group of eigenvectors; Other model parameters of the machine learning model, target loss value, optimization algorithm, training set test set validation set ratio, and loss function optimization are all achieved through actual engineering implementation and continuous experimental tuning.

[0065] The running time of the motor 231 is controlled according to the predicted centrifugal time; when the running time of the motor 231 is the same as the predicted centrifugal time, the motor 231 is controlled to stop running.

[0066] In summary, the control system collects comprehensive data information of the preparation device through the data acquisition module, including the weight and viscosity of the mixture and the vibration intensity and resistance data of the centrifuge cylinder 203, providing an accurate basis for adjusting the power of the motor 231.

[0067] The data analysis module of the control system generates a power influence coefficient based on the collected comprehensive data information, and determines and generates a corresponding power level, thereby realizing dynamic adjustment of the power of motor 231 to meet the needs under different working conditions. The control system can adjust the power of motor 231 according to actual needs, avoiding unnecessary energy waste and improving energy utilization efficiency.

[0068] This control system uses a time prediction module to train a machine learning model that predicts the centrifugal duration based on a historical training data set. It can predict the centrifugal duration, thereby controlling the operating time of the motor 231 and improving the efficiency of the centrifugal operation.

[0069] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

[0070] The preferred embodiments of the present invention disclosed above are only used to help explain the present invention. The preferred embodiments do not describe all the details in detail, nor do they limit the invention to only specific implementation methods. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the present invention, so that those skilled in the art can understand and use the present invention well. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A continuous reaction purification method for preparing an amino acid surfactant, characterized in that: The following steps are involved: Step 1, raw material preparation: prepare hydrophilic amino acid, natural fatty acid, catalyst and solvent for preparing amino acid surfactant, wherein the hydrophilic amino acid is glycine, the natural fatty acid is coconut oil fatty acid, the catalyst is toluenesulfonic acid, and the solvent is anhydrous ethanol; Step 2, continuous reaction: adding a hydrophilic amino acid, a natural fatty acid, a catalyst and a solvent into a mixing barrel (100) in a preparation device, and mixing the hydrophilic amino acid, the natural fatty acid, the catalyst and the solvent through a mixing mechanism (110) in the preparation device to allow the hydrophilic amino acid, the natural fatty acid, the catalyst and the solvent to fully react, wherein the molar ratio of the hydrophilic amino acid, the natural fatty acid, the catalyst and the solvent is 1:(1.05-1.2):(0.05-0.07):(10-15); Step 3, separation: opening the valve (106) in the preparation device, allowing the reaction mixture in the mixing cylinder (100) to be introduced into the centrifugal mechanism (200) in the preparation device, and separating the unreacted raw materials and by-products through the centrifugal mechanism (200) to obtain a crude product; Step 4: Continuous purification: The crude product is conveyed to a continuous crystallizer for further purification to separate the remaining unreacted products and impurities; Step 5: Collection and packaging: Collect the amino acid surfactant after continuous purification, and then package the collected products to prevent product degradation; The preparation device comprises: A mixing cylinder (100), with a feed pipe (102) and a connecting pipe (104) installed on the top, and a discharge pipe (105) and a plurality of support plates (107) installed on the bottom; A heating cylinder (101) mounted on the mixing cylinder (100); A mixing mechanism (110) for stirring the material in the mixing barrel (100); The centrifugal mechanism (200) is located directly below the mixing cylinder (100) and is in communication with the discharge pipe (105), and comprises: Drive assembly (230); A linkage assembly (220), used for driving the mixing mechanism (110) to operate; The centrifugal mechanism (200) further comprises: A fixed cylinder (201) fixedly connected to the lower ends of the plurality of support plates (107); A guide ring (202) mounted on the inner top surface of the fixed cylinder (201); A centrifugal cylinder (203) rotatably connected to the fixed cylinder (201) and the guide ring (202); A slag discharge pipe (204) is fixedly connected to the centrifugal cylinder (203), penetrates the bottom surface of the fixed cylinder (201) and is rotatably connected to the fixed cylinder (201); A plugging member (205) detachably connected to the slag discharge pipe (204); A gear ring (206) fixedly sleeved on the slag discharge pipe (204); A liquid discharge pipe (207) mounted on the fixed cylinder (201); The linkage assembly (220) comprises: A reducer (221) mounted on a side of the fixed cylinder (201); A vertical rod (222) connected to the output end of the reducer (221); Two first sprocket wheels (223) are both fixedly sleeved on the vertical rod (222); Two chains (224), wherein the chains (224) are sleeved on the first sprocket (223) and the second sprocket (214); A cam (225) mounted on the upper end of the vertical rod (222); A driven gear (226) connected to an input end of the reducer (221); The driving assembly (230) comprises: A motor (231) mounted on the bottom surface of the fixed cylinder (201); The driving gear (232) is fixedly connected to the power output shaft of the motor (231), and is meshingly connected to the driven gear (226) and the gear ring (206).

2. The continuous reaction and purification method for preparing an amino acid surfactant according to claim 1, characterized in that: The preparation device also includes: A top cover (103) detachably connected to the feed pipe (102); A valve (106) is installed on the discharge pipe (105).

3. The continuous reaction and purification method for preparing an amino acid surfactant according to claim 2, characterized in that: The mixing mechanism (110) comprises: A shaft (111) passes through the top surface of the mixing cylinder (100) and is rotatably connected to the mixing cylinder (100); A plurality of stirring plates (112), all located in the mixing barrel (100) and all fixedly connected to the shaft (111); A first gear (113) fixedly connected to the upper end of the shaft (111); A guide block (114) mounted on the top surface of the mixing cylinder (100); A rack (115) is slidably connected to the guide block (114), meshingly connected to the first gear (113), and in contact with the cam (225); A movable plate (116) fixedly connected to the rack (115); A fixing plate (117) fixedly connected to the top surface of the mixing cylinder (100); A plurality of springs (118) are installed between the movable plate (116) and the fixed plate (117).

4. The continuous reaction and purification method for preparing an amino acid surfactant according to claim 3, characterized in that: The centrifugal mechanism (200) further comprises a cleaning component (210), wherein the cleaning component (210) comprises: a cleaning ring (211), sleeved on the centrifugal cylinder (203), with a cleaning brush mounted on the inner wall thereof, the cleaning brush being in contact with the outer surface of the centrifugal cylinder (203); Two reciprocating screw nuts (212) are both installed through the cleaning ring (211); Two reciprocating screws (213), both of which penetrate the top surface of the fixed cylinder (201) and are rotatably connected to the fixed cylinder (201), and respectively penetrate the two reciprocating screw nuts (212); The two second sprockets (214) are respectively fixedly sleeved on the portion of the reciprocating screw (213) located outside the fixed cylinder (201).

5. The continuous reaction and purification method for preparing an amino acid surfactant according to claim 4, characterized in that: The preparation device also includes a control system, which includes: A data collection module, used to collect comprehensive data information of the preparation device, wherein the comprehensive data information includes weight data of the mixture, viscosity data of the mixture, vibration intensity data of the centrifugal cylinder (203), and resistance data of the centrifugal cylinder (203); The data analysis module receives the threshold range of the preset power impact coefficient set by the user, generates the power impact coefficient according to the comprehensive data information, and then compares the power impact coefficient with the threshold range of the preset power impact coefficient to determine and generate the corresponding power level; A data acquisition module, used to collect a historical training data set of the preparation device, the historical training data set including centrifugal comprehensive impact data and centrifugal duration; The time prediction module trains a machine learning model for predicting centrifugal duration based on a historical training data set, collects real-time centrifugal comprehensive impact data, and inputs it into the trained machine learning model to predict the centrifugal duration.

6. The continuous reaction and purification method for preparing an amino acid surfactant according to claim 5, characterized in that: The power influence coefficient is generated as follows: ； In the formula, is the power influence coefficient, is the weight data of the mixture, is the viscosity data of the mixture, is the vibration intensity data of the centrifuge cylinder (203), is the resistance data of the centrifugal cylinder (203); The power levels are generated as follows: The power levels include primary power, secondary power and tertiary power; The threshold range of the preset power influence coefficient is , , < ; like ,At this time, the data analysis module generates the first-level power; like ,At this time, the data analysis module generates secondary power; like ,At this time, the data analysis module generates level 3 power.

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