Bacterial drug resistance detection device

Abstract

The invention discloses a bacterial drug resistance detection device, and relates to the technical field of bacterial drug resistance detection. According to the bacterial drug resistance detection device, through the arrangement of the transmission frame and the sampling rod, when a sample is detected, the sample to be detected only needs to be put into the pore plate, and then the sampling rod can be inserted into the pore plate to transfer the sample to the glass slide through the operation of the sampling rod until the detection operation is completed, so that manual intervention can be reduced while the device is convenient to carry, and the detection efficiency is improved. Meanwhile, through the arrangement of the sampling rod, sampling can be completed through compression deformation of the elastic sampling piece during sampling, the sampling rod is reset along with the elastic sampling piece after use is completed, cleaning operation can be conveniently carried out on the sampling rod, operation continuity is guaranteed, and the situation that the detection result is affected due to mixed contamination of samples is avoided.

Description

Technical Field

[0001] The invention relates to the technical field of bacterial drug resistance detection, and in particular to a bacterial drug resistance detection device. Background Art

[0002] Drug-resistant bacterial infection has become a global problem, so drug resistance detection devices are needed to detect it qualitatively and quantitatively. Full spectrum refers to the spectrum curve that contains ultraviolet light, visible light, and infrared light, and the ratio of red, green, and blue in the visible light part is similar to that of sunlight, and the color rendering index is close to 100. Referring to the Chinese patent, the announcement number is "CN218239807U" "A portable full-spectrum bacterial resistance detection device", which points out that the existing detection device is inconvenient to carry when used; but the above-mentioned equipment still has the problem of poor convenience of use, and requires manual sampling, which is cumbersome and inconvenient to clean the sampling equipment, resulting in errors when testing multiple samples. In this regard, we propose a bacterial resistance detection device to solve the above problems. Summary of the invention

[0003] In view of the deficiencies of the prior art, the present invention provides a bacterial resistance detection device, which solves the problems raised in the above-mentioned background technology.

[0004] To achieve the above objectives, the present invention is implemented through the following technical solutions: a bacterial resistance detection device, comprising a box body, a cover rotatably installed on the top of the box body, a lock provided between the cover and the box body, a detection platform fixed on one side of the inside of the box body, a glass slide installed on the top of the detection platform, and detection modules provided on both sides of the top surface of the glass slide for detecting samples; A containing box is fixed on one side of the box body away from the testing table, and a perforated plate is placed inside the containing box. A sealing plate is rotatably connected to the top surface of the containing box, and a plurality of arc-shaped sealing sleeves adapted to the perforated plate are installed inside the sealing plate. Rectangular frames are fixed on both sides of the box body, and a transmission frame slides inside the rectangular frame, a sliding member slides outside the transmission frame, and a driving assembly is arranged between the sliding member, the transmission frame and the rectangular frame, for driving the sliding member to perform horizontal and vertical translation inside the box body; A sampling rod is installed inside the sliding part for sliding up and down. The sampling rod is used to be inserted into the corresponding well plate to extract the sample and then transport it to the slide. The end of the sampling rod is tapered and an arc-shaped limit ring is fixed inside. An elastic sampling piece is fixed at the end of the sampling rod. The elastic sampling piece can be compressed and retracted into the sampling rod until it fits with the arc-shaped limit ring to achieve sampling of the sample. A negative pressure machine connected to the sampling rod is fixed on the outside of the sliding part, and a plurality of ventilation holes are provided inside the arc-shaped limit ring.

[0005] Preferably, a driving motor is fixedly installed inside the sliding member for driving the sampling rod to slide up and down inside the sliding member, the output end of the driving motor is fixedly sleeved with a driving gear, the outer side of the sampling rod is fixedly installed with a toothed plate that meshes with the driving gear, the end of the sampling rod is fixedly sleeved with a positioning ring, the outer side of the sampling rod is sleeved with a spring body, and a connecting hose is connected between the end of the sampling rod and the negative pressure machine.

[0006] Preferably, the driving assembly includes a transmission belt, which is rotatably connected to the inside of a transmission frame, and a servo motor is fixedly installed inside the transmission frame to drive the transmission belt to operate, and the sliding member is fixedly connected to the outer side of the transmission belt, and telescopic tubes are provided inside the rectangular frames on both sides, and the telescopic tubes are installed between the end of the transmission frame and the inner wall of the rectangular frame, and a negative pressure device is fixedly installed inside the box, and connecting tubes are connected between the negative pressure device and the telescopic tubes on both sides.

[0007] Preferably, a support spring is fixedly installed inside the rectangular frame, and an end of the support spring is fixedly connected to the transmission frame.

[0008] Preferably, a plurality of sealing sleeves matched with the orifice plate are fixed to the bottom of the sealing plate, and the sealing sleeves and the top surface of the orifice plate are in contact with each other.

[0009] Preferably, two concave frames are fixed to the top surface of the detection table, the two concave frames are respectively located on both sides of the glass slide, and the detection modules are respectively fixed on the inner sides of the concave frames, and the top surface of the detection table is fixed with side panels, and the side of the side panel close to the glass slide is slidably connected with a cleaning plate, the installation height of the cleaning plate is flush with the glass slide, and is used for cleaning samples, and a collection rack is fixedly installed inside the detection table for collecting cleaned samples.

[0010] Preferably, a pushing cylinder is fixedly mounted on one side of the side plate away from the slide, and a piston end of the pushing cylinder passes through the side plate and is fixedly connected to the cleaning plate, so as to drive the cleaning plate to operate.

[0011] Preferably, a control panel is fixedly installed on the outside of the box, a control display device is fixedly installed on the inside of the box, the control display device is electrically connected to the control panel, a battery box is fixedly installed on the outside of the box, a middle partition is installed between the storage box and the testing table, and a transparent glass plate is fixedly installed on the inside of the cover.

[0012] Preferably, a cleaning box is fixedly installed inside the box body, a plurality of partition plates are fixedly installed inside the cleaning box, and a plurality of upper sealing plates are fixedly installed on the top surface of the cleaning box, and sealing rings are fixedly installed inside the upper sealing plates.

[0013] Preferably, an adsorption fiber layer is fixedly installed on one side of the interior of the cleaning box.

[0014] The present invention provides a bacterial resistance detection device. Compared with the prior art, it has the following beneficial effects: (1) The bacterial resistance detection device, through the setting of the transmission frame and the sampling rod, only needs to put the sample to be tested into the well plate when testing the sample, and then through the operation of the sampling rod, it can be inserted into the well plate to transfer the sample to the slide until the detection operation is completed. It is easy to carry and can reduce manual intervention, thereby improving the convenience of use of the equipment. At the same time, through the setting of the sampling rod, the elastic sampling piece can be compressed and deformed during sampling to complete the sampling. After the use is completed, the elastic sampling piece is reset, which can be convenient for cleaning, ensuring the continuity of the operation and avoiding the influence of sample mixing contamination on the detection result.

[0015] (2) The bacterial resistance detection device, through the sealing plate installed on the top surface of the containing box and the multiple arc-shaped sealing sleeves installed inside the sealing plate, can enable the sampling rod to pass through the arc-shaped sealing sleeve to complete the sampling operation when sampling. After the sampling rod is pulled out, the arc-shaped sealing sleeve automatically completes the sealing, thereby preventing the sample from being spilled or mixed when the box is shaken or hit, thereby improving the use effect of the equipment.

[0016] (3) The bacterial resistance detection device, through the setting of a cleaning box, allows the sampling rod to slide down after use and be inserted into multiple cleaning spaces in sequence. Then, through the cooperation of the adsorption fiber layer, the residual moisture on the surface of the sampling rod is adsorbed, which further improves the operating efficiency of the equipment and ensures the accuracy of detection. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the overall structure of the present invention; Figure 2 For the present invention Figure 1 Schematic diagram of the cross-section structure; Figure 3 For the present invention Figure 2 Look at the structural diagram; Figure 4 This is a schematic cross-sectional view of the structure of the container of the present invention; Figure 5 It is a schematic diagram of the cross-sectional structure of the detection platform of the present invention; Figure 6 This is a schematic diagram of the structure of the drive assembly of the present invention; Figure 7 For the present invention Figure 6 The enlarged structural diagram at A in the middle; Figure 8 It is a schematic diagram of the cross-sectional structure of the sliding member of the present invention; Fig. 9 For the present invention Figure 8 Enlarged structural diagram at B in the middle.

[0018] In the figure: 1, box; 101, control panel; 102, middle partition; 2, cover; 201, transparent glass plate; 202, lock; 3, battery box; 4, control display device; 5, test table; 6, slide; 7, concave frame; 701, test module; 8, side plate; 801, cleaning plate; 802, push cylinder; 9, collection rack; 10, storage box; 1001, sealing plate; 1002, sealing sleeve; 11, arc sealing sleeve; 12, orifice plate; 13, cleaning box; 1301, partition plate; 14, upper Sealing plate; 1401, sealing ring; 15, adsorption fiber layer; 16, rectangular frame; 1601, support spring; 17, transmission frame; 1701, transmission track; 1702, servo motor; 18, negative pressure device; 1801, connecting pipe; 19, telescopic pipe; 20, sliding part; 21, negative pressure machine; 22, sampling rod; 2201, positioning ring; 2202, spring body; 2203, connecting hose; 23, arc limit ring; 24, elastic sampling piece; 25, driving motor; 2501, driving gear; 26, gear plate. DETAILED DESCRIPTION

[0019] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0020] See also Figure 1-Figure 9 The present invention provides two technical solutions, which specifically include the following embodiments: Example 1: Reference Figure 1-Figure 5 A bacterial drug resistance detection device includes a box body 1, a cover 2 is rotatably installed on the top of the box body 1, a lock 202 is provided between the cover 2 and the box body 1, the lock 202 is an existing device, and is used to lock the cover 2 when it is closed, a detection table 5 is fixed to one side of the inside of the box body 1, a glass slide 6 is installed above the detection table 5, and detection modules 701 are provided on both sides of the top surface of the glass slide 6, and the detection module 701 is an existing spectrum detection instrument for detecting samples; Specifically, a holding box 10 is fixed on one side of the box body 1 away from the detection table 5, and a perforated plate 12 is placed inside the holding box 10. A sealing plate 1001 is rotatably connected to the top surface of the holding box 10, and a plurality of arc-shaped sealing sleeves 11 adapted to the perforated plate 12 are installed inside the sealing plate 1001. The perforated plate 12 is used to hold the sample. After the sample to be tested is placed in the perforated plate 12, the sealing plate 1001 is opened, and the perforated plate 12 is placed in the holding box 10 and then closed. The arc-shaped sealing sleeve 11 is used to ensure the sealing of the sample to prevent the sample from spilling when the box body 1 is shaken. For further reference, Figure 1-Figure 9 A rectangular frame 16 is fixed on both sides of the box body 1, and a transmission frame 17 is slidably arranged inside the rectangular frame 16. A sliding member 20 is slidably arranged outside the transmission frame 17. A driving assembly is arranged between the sliding member 20, the transmission frame 17 and the rectangular frame 16, for driving the sliding member 20 to perform horizontal and vertical translation inside the box body 1; a sampling rod 22 is installed inside the sliding member 20 for sliding up and down movement, and the sampling rod 22 is used to be inserted into the corresponding orifice plate 12 to extract the sample and then transport it to the slide glass 6. The end of the sampling rod 22 is conical and an arc-shaped limiting ring 23 is fixed inside. An elastic sampling piece 24 is fixed at the end of the sampling rod 22, and the elastic sampling piece 24 can be pressed to The sampling rod 22 retracts inside until it fits with the arc-shaped limiting ring 23 to achieve sampling of the sample. A negative pressure machine 21 connected to the sampling rod 22 is fixedly installed on the outside of the sliding member 20. A plurality of vents are provided inside the arc-shaped limiting ring 23. When sampling and testing is performed, as the sampling rod 22 moves to the sampling position, it slides downward and can pass through the corresponding arc-shaped sealing sleeve 11 to reach the orifice plate 12. Then, as the negative pressure machine 21 operates, the elastic sampling sheet 24 can be compressed and retracted into the sampling rod 22 to extract the sample. Then, the sampling rod 22 slides upward to move above the glass slide 6, and the extracted sample is moved above the glass slide 6 for testing. Specifically, the negative pressure machine 21 is an existing negative pressure device, which can generate negative pressure inside the sampling rod 22 through operation, so that the elastic sampling piece 24 can be compressed and retracted into the sampling rod 22 until it fits with the arc-shaped limit ring 23. The elastic sampling piece 24 can extract the sample during the deformation process until it moves to the top of the glass slide 6. The negative pressure machine 21 stops running, and the elastic sampling piece 24 can be reset, so that the sample flows to the top of the glass slide 6 for detection. In this way, the convenience of batch detection of samples can be further improved, and the contact area between the sample and the sampling device can be reduced, thereby avoiding the phenomenon of mixed contamination of the sample. Specifically, a driving motor 25 is fixedly installed inside the sliding member 20, which is used to drive the sampling rod 22 to slide up and down inside the sliding member 20. A driving gear 2501 is fixedly sleeved on the output end of the driving motor 25, and a tooth plate 26 meshing with the driving gear 2501 is fixedly installed on the outside of the sampling rod 22. A positioning ring 2201 is fixedly sleeved on the end of the sampling rod 22, and a spring body 2202 is sleeved on the outside of the sampling rod 22. A connecting hose 2203 is connected between the end of the sampling rod 22 and the negative pressure machine 21. As the driving motor 25 runs, the driving gear 2501 can be driven to rotate, so that the sampling rod 22 can slide up and down inside the sliding member 20 through the cooperation of the tooth plate 26. The driving motor 25 is an existing forward and reverse motor. Specifically, the driving assembly includes a transmission track 1701, which is rotatably connected to the inside of the transmission frame 17, and a servo motor 1702 is fixedly installed inside the transmission frame 17 for driving the transmission track 1701 to run. The sliding member 20 is fixedly connected to the outer side of the transmission track 1701. As the servo motor 1702 drives the transmission track 1701 to run, it can drive the sliding member 20 to slide on the outer side of the transmission frame 17, so that the sliding member 20 can achieve lateral translation. Telescopic tubes 19 are provided inside the rectangular frames 16 on both sides, and the telescopic tubes 19 are installed between the end of the transmission frame 17 and the inner wall of the rectangular frame 16. A negative pressure device 18 is fixedly installed inside the box body 1, and connecting tubes 1801 are connected between the negative pressure device 18 and the telescopic tubes 19 on both sides. The operation of the negative pressure device 18 can drive the telescopic tube 19 to extend. As the telescopic tube 19 extends, it can push the transmission frame 17 to slide inside the rectangular frame 16, so that the sliding member 20 can achieve longitudinal translation. Specifically, a support spring 1601 is fixedly installed inside the rectangular frame 16, and the end of the support spring 1601 is fixedly connected to the transmission frame 17, and the support spring 1601 is used to support the transmission frame 17; For further reference, Figure 4 A plurality of sealing sleeves 1002 adapted to the orifice plate 12 are fixed at the bottom of the sealing plate 1001, and the sealing sleeves 1002 and the top surface of the orifice plate 12 are in contact with each other. By setting the sealing sleeves 1002, when the sealing plate 1001 is closed, the sealing sleeves 1002 and the top surface of the orifice plate 12 are in contact with each other, so that the multiple samples inside the orifice plate 12 are separated, thereby avoiding the phenomenon of mixed contamination and ensuring the accuracy of subsequent detection; For further reference, Figure 5Two concave frames 7 are fixed on the top surface of the detection table 5, and the two concave frames 7 are respectively located on both sides of the glass slide 6, and the detection modules 701 are respectively fixed on the inner sides of the concave frames 7. A side plate 8 is fixed on the top surface of the detection table 5. A cleaning plate 801 is slidably connected to the side of the side plate 8 close to the glass slide 6. The installation height of the cleaning plate 801 is flush with the glass slide 6 and is used to clean the sample. A collecting rack 9 is fixedly installed inside the detection table 5 for collecting the cleaned samples. When the sample above the glass slide 6 is tested, the sample above the glass slide 6 can be pushed to the collecting rack 9 as the cleaning plate 801 runs, and the collection is completed by the collecting rack 9, thereby realizing an automatic cleaning process; Specifically, a push cylinder 802 is fixedly installed on one side of the side plate 8 away from the slide glass 6, and a piston end of the push cylinder 802 passes through the side plate 8 and is fixedly connected to the cleaning plate 801, so as to drive the cleaning plate 801 to operate; A control panel 101 is fixedly installed on the outside of the box 1, a control display device 4 is fixedly installed inside the box 1, the control display device 4 is electrically connected to the control panel 101, the control panel 101 is based on an existing PLC control module, a battery box 3 is fixedly installed on the outside of the box 1, a middle partition 102 is installed between the storage box 10 and the detection table 5, and a transparent glass plate 201 is fixedly installed inside the cover 2, and the transparent glass plate 201 is used for observation operations; Specifically, the plurality of arc-shaped sealing sleeves 11 and the sealing ring 1401 are all made of elastic material, and each has a slit formed therein for the sampling rod 22 to pass through.

[0021] Embodiment 2: Based on embodiment 1, on the basis of embodiment 1, a cleaning box 13 is fixedly installed inside the box body 1, a plurality of partition plates 1301 are fixedly installed inside the cleaning box 13, and a plurality of upper sealing plates 14 are fixedly installed on the top surface of the cleaning box 13, and a sealing ring 1401 is fixedly installed inside the upper sealing plates 14. The cleaning box 13 is used to clean the end of the sampling rod 22 after use. The interior of the cleaning box 13 is divided into a plurality of cleaning spaces by a plurality of partition plates 1301, and the cleaning spaces are all injected with cleaning liquid. When the sampling rod 22 is used, it can be moved to the top of the cleaning space in turn and inserted into the cleaning space. , the cleaning process is completed. During the insertion process, the sampling rod 22 can pass through the sealing ring 1401 and contact the cleaning water. At this time, the elastic sampling piece 24 maintains the initial state, and contacts with the cleaning water inside the multiple cleaning spaces to ensure the cleaning effect; an adsorption fiber layer 15 is fixedly installed on one side of the interior of the cleaning box 13, and an adsorption layer is provided on the side of the cleaning box 13 close to the control display device 4. The adsorption layer is provided inside the adsorption fiber layer 15. When the cleaned sampling rod 22 is inserted into the adsorption fiber layer 15, the moisture remaining on the surface of the sampling rod 22 can be adsorbed by the adsorption fiber layer 15, which is convenient for subsequent sampling processing.

[0022] Meanwhile, the contents not described in detail in this specification belong to the prior art known to those skilled in the art.

[0023] The above is a detailed description of an embodiment of the present invention, but the content is only a preferred embodiment of the present invention and cannot be considered to limit the scope of implementation of the present invention. All equivalent changes and improvements made within the scope of the present invention should still fall within the scope of the present invention.

Claims

1. A bacterial drug resistance detection device, comprising a housing (1), a cover (2) rotatably mounted on the housing (1), a locking member (202) being provided between the cover (2) and the housing (1), characterized in that: A detection platform (5) is fixed on one side of the interior of the box (1), a glass slide (6) is installed above the detection platform (5), and detection modules (701) are provided on both sides of the top surface of the glass slide (6) for detecting samples; A containing box (10) is fixed to a side of the box body (1) away from the testing table (5), and a perforated plate (12) is placed inside the containing box (10); a sealing plate (1001) is rotatably connected to the top surface of the containing box (10), and a plurality of arc-shaped sealing sleeves (11) adapted to the perforated plate (12) are installed inside the sealing plate (1001); A rectangular frame (16) is fixed on both sides of the box body (1), and a transmission frame (17) is slidably disposed inside the rectangular frame (16), and a sliding member (20) is slidably disposed outside the transmission frame (17). A driving assembly is disposed between the sliding member (20), the transmission frame (17) and the rectangular frame (16), and is used to drive the sliding member (20) to perform horizontal and vertical translation inside the box body (1); A sampling rod (22) is installed inside the sliding member (20) for sliding up and down. The sampling rod (22) is used to be inserted into the corresponding well plate (12) to extract the sample and then transport it to the glass slide (6). The end of the sampling rod (22) is conical and an arc-shaped limiting ring (23) is fixed inside. An elastic sampling piece (24) is fixed to the end of the sampling rod (22). The elastic sampling piece (24) can be compressed and retracted into the sampling rod (22) until it fits with the arc-shaped limiting ring (23) to achieve sampling of the sample. A negative pressure machine (21) connected to the sampling rod (22) is fixedly installed outside the sliding member (20). A plurality of ventilation holes are opened inside the arc-shaped limiting ring (23).

2. A bacterial resistance detection device according to claim 1, characterized in that: A driving motor (25) is fixedly mounted inside the sliding member (20) for driving the sampling rod (22) to slide up and down inside the sliding member (20); a driving gear (2501) is fixedly sleeved on the output end of the driving motor (25); a toothed plate (26) meshing with the driving gear (2501) is fixedly mounted on the outside of the sampling rod (22); a positioning ring (2201) is fixedly sleeved on the end of the sampling rod (22); a spring body (2202) is sleeved on the outside of the sampling rod (22); and a connecting hose (2203) is connected between the end of the sampling rod (22) and the negative pressure machine (21).

3. A bacterial resistance detection device according to claim 1, characterized in that: The driving assembly comprises a transmission crawler (1701), wherein the transmission crawler (1701) is rotatably connected to the inside of a transmission frame (17), a servo motor (1702) is fixedly installed inside the transmission frame (17) for driving the transmission crawler (1701) to operate, the sliding member (20) is fixedly connected to the outside of the transmission crawler (1701), telescopic tubes (19) are provided inside the rectangular frames (16) on both sides, and the telescopic tubes (19) are installed between the end of the transmission frame (17) and the inner wall of the rectangular frame (16), and a negative pressure device (18) is fixedly installed inside the box body (1), and connecting tubes (1801) are connected between the negative pressure device (18) and the telescopic tubes (19) on both sides.

4. A bacterial resistance detection device according to claim 3, characterized in that: A support spring (1601) is fixedly installed inside the rectangular frame (16), and an end of the support spring (1601) is fixedly connected to the transmission frame (17).

5. A bacterial resistance detection device according to claim 1, characterized in that: A plurality of sealing sleeves (1002) adapted to the orifice plate (12) are fixed to the bottom of the sealing plate (1001), and the sealing sleeves (1002) and the top surface of the orifice plate (12) are in contact with each other.

6. A bacterial resistance detection device according to claim 1, characterized in that: Two concave frames (7) are fixed on the top surface of the detection table (5), and the two concave frames (7) are respectively located on both sides of the glass slide (6), and the detection modules (701) are respectively fixed on the inner sides of the concave frames (7). A side plate (8) is fixed on the top surface of the detection table (5), and a cleaning plate (801) is slidably connected to the side of the side plate (8) close to the glass slide (6). The installation height of the cleaning plate (801) is flush with the glass slide (6) and is used for cleaning samples. A collection frame (9) is fixedly installed inside the detection table (5) and is used for collecting cleaned samples.

7. A bacterial resistance detection device according to claim 6, characterized in that: A push cylinder (802) is fixedly mounted on the side of the side plate (8) away from the glass slide (6); a piston end of the push cylinder (802) passes through the side plate (8) and is fixedly connected to the cleaning plate (801) for driving the cleaning plate (801) to operate.

8. A bacterial resistance detection device according to claim 1, characterized in that: A control panel (101) is fixedly mounted on the outside of the box (1), a control display device (4) is fixedly mounted inside the box (1), and the control display device (4) is electrically connected to the control panel (101), a battery box (3) is fixedly mounted on the outside of the box (1), a middle partition (102) is mounted between the storage box (10) and the detection table (5), and a transparent glass plate (201) is fixedly mounted inside the cover (2).

9. A bacterial resistance detection device according to claim 1, characterized in that: A cleaning box (13) is fixedly installed inside the box body (1), a plurality of partition plates (1301) are fixedly installed inside the cleaning box (13), and a plurality of upper sealing plates (14) are fixedly installed on the top surface of the cleaning box (13), and a sealing ring (1401) is fixedly installed inside each of the upper sealing plates (14).

10. A bacterial resistance detection device according to claim 9, characterized in that: An adsorption fiber layer (15) is fixedly mounted on one side of the interior of the cleaning box (13).

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