Column oven capable of independently taking and placing single group of chromatographic columns

Abstract

The invention relates to the technical field of temperature boxes, in particular to a column temperature box capable of independently taking and placing a single group of chromatographic columns, the column temperature box comprises a ring seat, a support leg is fixedly mounted at the top of the ring seat, a box body is fixedly mounted at the top of the support leg, and a hinge piece is fixedly mounted at the upper end of one side of the box body. During use, chromatographic columns can be placed on the inner sides of the clamping plates, limiting springs in the elastic seats enable the clamping plates to stably clamp and position the chromatographic columns, the multiple chromatographic columns can be stably arranged in the box body, during column taking, the linear displacement mechanism and the rotating mechanism are matched to move the chromatographic columns to a column taking opening, a first motor is started, a ball and a driving wheel are attached to the chromatographic columns correspondingly, and the chromatographic columns are taken out. The driving wheel rotates to extrude and drive the chromatographic column, the driving wheel and the ball roll to reduce friction force, so that the chromatographic column is quickly and stably moved out, a sealing box cover does not need to be opened, the rotating mechanism and the linear displacement mechanism are matched, the chromatographic column can be independently taken and placed, and the condition of temperature imbalance of the chromatographic column is avoided.

Description

Technical Field

[0001] The present application relates to the technical field of temperature chambers, and in particular to a column temperature chamber capable of independently taking in and placing a single set of chromatographic columns. Background Art

[0002] At present, the column oven of the chromatographic column is an important device for accurately controlling the temperature of the chromatographic column in chromatographic analysis. It usually consists of a box with good thermal insulation performance, a temperature control system and a heating / cooling element. The main function of the column oven is to provide a stable and controllable temperature environment for the chromatographic column. By accurately adjusting the temperature, the chromatographic separation effect can be improved, the symmetry and resolution of the peak shape can be improved, and the tailing phenomenon of the chromatographic peak can be reduced. Different samples and analysis methods may require different column temperature conditions. The column oven can meet these diverse needs. Through searching, a liquid chromatography column temperature box with Chinese patent announcement number CN213337496U is found, which includes a box body, a box door, and a heat conducting plate. At least one chromatography column groove is provided on the front of the heat conducting plate; a wire entry hole and a wire outlet hole are provided at both ends of the chromatography column groove respectively; a plurality of pipeline grooves and temperature sensor grooves are provided on the back of the heat conducting plate; and the back of the heat conducting plate is in contact with the heating element.

[0003] With respect to the above-mentioned related technologies, the inventors found the following defects: However, the above-mentioned chromatographic column oven still has some significant shortcomings. When the chromatographic column needs to be taken out, the oven cover is directly opened, and all the chromatographic columns are completely exposed to the external environment. This situation can easily lead to temperature imbalance of the remaining chromatographic columns, which in turn has an adverse effect on the solution separation effect. It should be noted that the temperature stability of the chromatographic column is crucial to the accuracy and effectiveness of solution separation. A slight change in temperature may cause a deviation in the separation effect. In addition, the heating method through the heat conduction plate still has the problem of uneven heating, which means that different parts of the chromatographic column may be heated to different degrees, thereby affecting the overall temperature consistency, and then interfering with the accuracy and repeatability of the separation process. For example, in some experiments that are extremely sensitive to temperature, uneven heating may cause the local temperature of the chromatographic column to be too high or too low, resulting in incomplete separation of the target substance or the appearance of impurity peaks, which seriously affects the reliability and scientificity of the experimental results. In summary, these defects limit the performance and application effect of the chromatographic column oven to a certain extent. Therefore, we propose a new type of chromatographic column oven to solve the above problems. Summary of the invention

[0004] In order to avoid the situation where the temperature of the chromatographic columns is unbalanced, the present application provides a column temperature oven that can independently take out and put in a single group of chromatographic columns.

[0005] The present application provides a column temperature box capable of independently taking in and placing a single group of chromatographic columns, adopting the following technical scheme: comprising a ring seat, a support leg fixedly mounted on the top of the ring seat, a box body fixedly mounted on the top of the support leg, a hinge fixedly mounted on the upper end of one side of the box body, a sealed box cover hingedly connected to the box body through the hinge, a column taking port opened on one side of the top of the sealed box cover, a sealing cover connected to the inner thread of the column taking port, a rotating mechanism fixedly mounted on the bottom of the ring seat, a linear displacement mechanism fixedly mounted on the top of the rotating mechanism at equal intervals, a clamping mechanism fixedly connected to the top of the linear displacement mechanism in a linear arrangement at equal intervals, a chromatographic column clamped inside the clamping mechanism, a reserved shell fixedly mounted on the middle of the front side of the box body, and a temperature sensor arranged inside the box body; The clamping mechanism includes a fixed seat, which is fixedly installed on the top of the linear displacement mechanism at equal intervals. Elastic seats are fixedly installed on both sides of the top of the fixed seat, and a clamping plate is fixedly installed on the inner side of the elastic seat. A power component is fixedly installed on the inner side of an elastic seat.

[0006] Optionally, a drain pipe is fixedly installed at the bottom of the box body, and a sealing cover is also threadedly connected to the outer end of the drain pipe.

[0007] Optionally, a fixing plate is fixedly installed in the middle of the top right end of the reserved shell, a limiting hole is opened in the middle of the front side of the sealed box cover, the upper end of the fixing plate is threadedly connected with a hand-tightened screw, and the rear end of the hand-tightened screw is inserted into the inside of the limiting hole.

[0008] Optionally, the elastic seat includes a mounting frame, which is fixedly installed on both sides of the top of the fixed seat, and limit springs are fixedly installed at equal intervals inside the mounting frame. A movable block is fixedly installed on the end of the limit spring, and the movable block is slidably connected to the inner side of the mounting frame, and the clamping plate is fixedly connected to the inner side of the movable block.

[0009] Optionally, the power assembly includes a square groove, which is opened at the top and bottom of a mounting frame, and the interior of the square groove is rotatably connected to a driving wheel. A first motor is fixedly installed on the upper end of one side of the mounting frame, and the first motor is configured to be a waterproof motor. The output end of the first motor passes through the mounting frame and is fixedly connected to the driving wheel at the upper end, and the inner side of the driving wheel is fit-fittingly connected to the chromatographic column.

[0010] Optionally, the overall cross-sectional shape of the clamping plate is V-shaped, a clamping plate is fixedly installed on the inner side of the clamping plate, and balls are rotatably connected to the inner side of the clamping plate at equal intervals.

[0011] Optionally, the rotating mechanism includes a second motor, which is fixedly installed in the middle of the bottom of the box. The output end of the second motor passes through the box and is fixedly installed with a movable ring. The movable ring is rotatably connected to the bottom of the box. The linear displacement mechanisms are fixedly installed at equal intervals on the top of the movable ring. The top of the movable ring is located in the gap between each linear displacement mechanism and is fixedly installed with a heating wire. The heating wire is arranged in a spiral shape.

[0012] Optionally, fixed blocks are fixedly installed at equal intervals on the bottom of the movable ring, and the bottoms of the fixed blocks are rotatably connected to universal balls, and the bottoms of the universal balls are fit-connected to the bottom of the box body.

[0013] Optionally, the linear displacement mechanism includes a base, which is arranged in a ring at equal intervals and fixedly installed on the top of the movable ring, a third motor is fixedly installed on the inner end of the base, an output end of the third motor passes through the base and is fixedly installed with a screw rod, the screw rod is rotatably connected to the inside of the base, a slide is slidably connected to the top of the base, the slide and the screw rod are threadedly connected, and the fixed seat is fixedly installed on the top of the slide at equal intervals.

[0014] Optionally, the overall cross-sectional shape of the lower end of the slide is convex, the overall cross-sectional shape of the inner lower end of the base is also convex, and encoders are installed on the shaft ends of the first motor, the second motor and the third motor.

[0015] In summary, this application includes the following beneficial technical effects: 1. When the chromatographic column needs to be taken out, the second motor is started to drive the movable ring to rotate at the bottom of the box, thereby assisting in adjusting the linear displacement mechanism at the top to cyclically move to the column taking port. When the required chromatographic column arrives at the column taking port, the third motor is started to drive the screw to rotate, causing the slide to slide on the top of the base, and accurately moving the chromatographic columns in each clamping mechanism to the column taking port. The linear displacement mechanism can not only adjust the movement of the chromatographic column to the taking port, but also can change its position during the movement process with the help of the rotation of the movable ring. In addition, the encoder can accurately control the number of rotations of the output shafts of the first, second, and third motors, so that each chromatographic column can be accurately aligned with the column taking port. All chromatographic columns can be taken and placed through only one column taking port, which greatly improves the convenience of the device, effectively prevents the temperature imbalance of the chromatographic column, and significantly improves the accuracy of the detection; 2. Add water to the inside of the box and start the electric heating wire to heat the water. The heated water can preheat the chromatographic column and make it heat up quickly and evenly. Hot water can not only help to quickly and stably increase the temperature, but also has excellent uniform insulation performance, effectively avoiding temperature imbalance in the chromatographic column. When taking out the column, twist open the sealing cover to open the column taking port. Through the coordinated cooperation of the rotating mechanism, the clamping mechanism and the linear displacement mechanism, the chromatographic column can be smoothly removed from the inside of the column taking port, which significantly improves the convenience of the device during use. After use, loosen the hand-tightening bolt to remove it from the limit hole, then open the sealing cover of the sealing box cover and the sealing cover of the drain pipe to drain the water. At the same time, the inside of the box can also be opened for easy inspection and maintenance. 3. By placing the chromatographic column between the inner sides of the clamping plates, due to the presence of the elastic seat, the limit spring inside the mounting frame provides elastic force, so that the clamping plate is resisted and moves inward, so that the chromatographic column can be stably clamped and positioned. With the setting of this clamping mechanism, multiple chromatographic columns can be stably installed inside the box. When the chromatographic column needs to be taken out, the chromatographic column is moved to the column taking port through the coordinated cooperation of the linear displacement mechanism and the rotation mechanism. At this time, the first motor is started. Since the inner side of the ball fits the chromatographic column, the inner side of the driving wheel also fits the outer surface of the chromatographic column. The first motor drives the driving wheel at the upper end to rotate. Under the extrusion drive of the driving wheel on the chromatographic column, the friction force on the outer surface of the chromatographic column is reduced by the rolling of the driving wheel and the ball, so that the chromatographic column can be quickly and stably moved out from the column taking port, so that the chromatographic column can be taken out from the inside of the box without opening the sealed box cover, which greatly improves the overall convenience of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the overall structure in the embodiment of the present application; Figure 2 This is a schematic diagram of the structure viewed from above in an embodiment of the present application; Figure 3 This is a schematic diagram of the structure of the sealed box cover in the open state in the embodiment of the present application; Figure 4 It is a schematic diagram of the overall structure of the movable ring, the linear displacement mechanism and the clamping mechanism in the embodiment of the present application; Figure 5 It is a bottom view structural diagram of the movable ring, the single set of linear displacement mechanism and the clamping mechanism in the embodiment of the present application; Figure 6 It is a schematic diagram of a top view of the structure of a movable ring, a single set of linear displacement mechanisms and a clamping mechanism in an embodiment of the present application; Figure 7 This is a schematic diagram of the structure of the linear displacement mechanism and the clamping mechanism in the embodiment of the present application in the split state; Figure 8 It is a schematic diagram of the structure of the clamping mechanism in the embodiment of the present application.

[0017] 1. The support leg of the second motor is provided with a plurality of support members, and the support members are provided with a plurality of support members. The support members are provided with a plurality of support members, and the support members are provided with a plurality of support members. The support members are provided with a plurality of support members, and the support members are provided with a plurality of support members. DETAILED DESCRIPTION

[0018] The following is combined with Figure 1-8 This application is described in further detail.

[0019] The present application embodiment discloses a column oven that can independently take in and out a single set of chromatographic columns. Figure 1-8 As shown, it comprises a ring seat 1, a support leg 2 is fixedly installed on the top of the ring seat 1, a box body 3 is fixedly installed on the top of the support leg 2, a hinge 4 is fixedly installed on the upper end of one side of the box body 3, a sealed box cover 5 is hingedly connected to the box body 3 through the hinge 4, a column taking port 6 is opened on one side of the top of the sealed box cover 5, a sealing cover 7 is connected to the inner thread of the column taking port 6, a rotating mechanism 8 is fixedly installed on the bottom of the ring seat 1, a linear displacement mechanism 9 is fixedly installed at an equal interval on the top of the rotating mechanism 8, a clamping mechanism 10 is fixedly connected to the top of the linear displacement mechanism 9 in a linear arrangement at an equal interval, a chromatographic column is clamped inside the clamping mechanism 10, a reserved shell 11 is fixedly installed on the middle of the front side of the box body 3, and a temperature sensor is arranged inside the box body 3;

[0020] The clamping mechanism 10 includes a fixed seat 101, which is fixedly installed on the top of the linear displacement mechanism 9 at equal intervals. Elastic seats 102 are fixedly installed on both sides of the top of the fixed seat 101. A clamping plate 104 is fixedly installed on the inner side of the elastic seat 102. A power assembly 103 is fixedly installed on the inner side of an elastic seat 102. The ring seat 1 firmly supports the box body 3 through the supporting legs 2. The sealed box cover 5 connected to one side of the box body 3 by a hinge 4 is convenient for opening and closing. The column taking port 6 and the sealing cover 7 connected with the internal thread ensure the sealing when the column is not taken. The rotating mechanism 8 at the bottom of the ring seat 1 cooperates with the linear displacement mechanism 9 at equal intervals on the top. The displacement mechanism 9 can accurately adjust the position of the clamping mechanism 10 to achieve independent placement of a single group of chromatographic columns, thereby improving the flexibility and pertinence of the operation. The fixed seat 101, the elastic seat 102 and the clamping plate 104 in the clamping mechanism 10 cooperate with each other to stably clamp the chromatographic columns, and the power component 103 further enhances the convenience and efficiency of the placement operation. The temperature sensor arranged in the box 3 helps to accurately monitor the internal temperature to ensure that the chromatographic columns are in a suitable temperature environment. The overall structural design is reasonable, the functions are complete, the operation is convenient, and the temperature control and placement requirements of the chromatographic columns during use can be effectively met.

[0021] Please refer to Figure 1-Figure 3 A drain pipe 12 is fixedly installed at the bottom of the box body 3, and a sealing cover 7 is also threadedly connected to the outer end of the drain pipe 12. A fixing plate 13 is fixedly installed in the middle of the top right end of the reserved shell 11. A limiting hole 15 is opened in the middle of the front of the sealing box cover 5. A hand-tightening screw 14 is threadedly connected to the upper end of the fixing plate 13. The rear end of the hand-tightening screw 14 is inserted into the inner part of the limiting hole 15. The setting of the reserved shell 11 can reserve space for the sliding of the slide 94 when the chromatographic column needs to be taken and placed. The drain pipe 12 at the bottom of the box body 3 and the sealing cover 7 at its outer end are convenient for After use, the liquid in the box is discharged to facilitate cleaning and maintenance. The fixed plate 13 in the middle of the top right end of the reserved shell 11 is connected and fixed with the limiting hole 15 in the middle of the front of the sealed box cover 5 by a hand-tightened screw 14, ensuring the stability of the sealed box cover 5 when closed, and convenient operation when it needs to be opened. The setting of the reserved shell 11 is even more ingenious, and sufficient space is reserved for the sliding of the slide 94 when taking and placing the chromatographic column, ensuring the smooth operation, making the entire taking and placing process smoother and more efficient, and improving the convenience and flexibility of using the column oven.

[0022] Please refer to Figure 3-Figure 6The elastic seat 102 includes a mounting frame 1021, which is fixedly installed on both sides of the top of the fixed seat 101. Limit springs 1022 are fixedly installed at equal intervals inside the mounting frame 1021. A movable block 1023 is fixedly installed on the end of the limit spring 1022. The movable block 1023 is slidably connected to the inner side of the mounting frame 1021. The clamping plate 104 is fixedly connected to the inner side of the movable block 1023. The power component 103 includes a square groove 1031. The square groove 1031 is opened at the top and bottom of a mounting frame 1021. The inner rotation of the square groove 1031 is connected to a driving wheel 1032. A first motor 1033 is fixedly installed on the upper end of one side of the mounting frame 1021. The first motor 1033 is set to be a waterproof motor. The output end of the first motor 1033 passes through the mounting frame 1021 and is fixedly connected to the driving wheel 1032 at the upper end. The inner side of the driving wheel 1032 is fitted and connected with the chromatographic column. The overall cross-sectional shape of the clamping plate 104 is V-shaped. The clamping plate 104 is fixedly installed on the inner side of the clamping plate 104. The inner side of the clamping plate 104 is rotatably connected with the ball bearings 105 at equal intervals. The mounting frame 1021 in the elastic seat 102 provides a stable mounting position for the limit spring 1022 and the movable block 1023. The limit springs 1022 arranged at equal intervals provide a uniform and flexible clamping force for the clamping plate 104 through the movable block 1023, which can stably clamp the chromatographic column and ensure the stability of the clamping. The driving wheel 1032 rotatably connected in the square groove 1031 in the power component 103 can operate accurately under the drive of the waterproof first motor 1033, and the inner side of the driving wheel 1032 is fitted with the chromatographic column to provide power for the movement of the chromatographic column. The clamping plate 104 is V-shaped as a whole. The inner clamping plate 104 is provided with equally spaced rotating balls 105, which on the one hand further enhance the clamping stability of the chromatographic column, and on the other hand, the rotation of the balls 105 can effectively reduce the friction when the chromatographic column moves, making the removal and placement of the chromatographic column smoother, more efficient and more precise.

[0023] Please refer to Figure 2-Figure 4The rotating mechanism 8 includes a second motor 81, which is fixedly installed in the middle of the bottom of the box body 3. The output end of the second motor 81 passes through the box body 3 and is fixedly installed with a movable ring 82. The movable ring 82 is rotatably connected to the bottom of the box body 3. The linear displacement mechanism 9 is fixedly installed at the top of the movable ring 82 at equal intervals. The top of the movable ring 82 is located at the gap between each linear displacement mechanism 9 and is fixedly installed with a heating wire 83. The heating wire 83 is arranged in a spiral shape. The bottom of the movable ring 82 is fixedly installed with a fixed block 84 at equal intervals. The bottom of the fixed block 84 is rotatably connected with a universal ball 85. The bottom of the universal ball 85 is fitted and connected to the bottom of the box body 3. The second motor 81 is fixedly installed in the middle of the bottom of the box body 3, and its output end passes through the movable ring 82 connected to the box body 3. The ring 82 can realize stable and precise rotation control. The movable ring 82 is rotatably connected to the bottom of the box body 3, providing reliable support and flexible rotation basis for the linear displacement mechanism 9. The linear displacement mechanism 9 fixedly installed on the top of the movable ring 82 at equal intervals can realize precise position adjustment during the rotation process. The spirally arranged heating wire 83 can not only provide heat to the box body 3 evenly, but also effectively utilize the space and improve the heating efficiency. The fixed blocks 84 fixed at equal intervals at the bottom of the movable ring 82 and the universal ball 85 rotatably connected to the bottom of the movable ring 82 are fitted and connected to the bottom of the box body 3, which plays a good role in supporting and assisting the rotation, reducing the resistance and wear of the movable ring 82 during rotation, and ensuring the smoothness and durability of the rotation.

[0024] Please refer to Figure 3-Figure 7The linear displacement mechanism 9 includes a base 91, which is arranged in a ring at equal intervals and fixedly installed on the top of the movable ring 82. A third motor 92 is fixedly installed on the inner end of the base 91. The output end of the third motor 92 passes through the base 91 and is fixedly installed with a screw rod 93. The screw rod 93 is rotatably connected to the inside of the base 91. A slide 94 is slidably connected to the top of the base 91. The slide 94 and the screw rod 93 are threadedly connected. The fixed seat 101 is fixedly installed on the top of the slide 94 at equal intervals. The overall cross-sectional shape of the lower end of the slide 94 is convex, and the overall cross-sectional shape of the lower end of the base 91 is also convex. The shaft ends of the first motor 1033, the second motor 81 and the third motor 92 are all equipped with encoders. The base 91 is arranged in a ring at equal intervals and fixed on the top of the movable ring 82. The structure is reasonable and stable. The third motor 92 at the inner end of the base 91 can provide precise rotational power for the screw rod 93. The rotation of the screw rod 93 drives the slide 94 threadedly connected thereto to slide on the top of the base 91, thereby realizing precise linear displacement control. The convex cross-section design of the lower end of the slide 94 and the lower end of the inner part of the base 91 enhances the stability and guidance of the sliding connection and prevents the slide 94 from offsetting or shaking during movement. The fixed seat 101 is fixed at equal intervals on the top of the slide 94 to ensure the accurate position of the clamped chromatographic column. In addition, the encoders installed on the shaft ends of the first motor 1033, the second motor 81 and the third motor 92 can accurately measure and control the rotation of the motors, further improving the precision and accuracy of the linear displacement and meeting the demand for precise adjustment of the position of the chromatographic column.

[0025] The implementation principle of a column temperature oven capable of independently taking in and placing a single set of chromatographic columns in the embodiment of the present application is as follows: during the use of the device, when the chromatographic column needs to be taken out, the second motor 81 can be started to drive the movable ring 82 to rotate at the bottom of the box body 3, and the movable ring 82 can be rotated inside the box body 3 to assist in adjusting and drive the linear displacement mechanism 9 on its top to cyclically move to the column taking port 6. When the chromatographic column to be taken out moves to the column taking port 6, the third motor 92 can be started to operate. Once the third motor 92 is running, the screw rod 93 can be driven to rotate. The rotation of the screw rod 93 will drive the slide 94 to slide on the top of the base 91. Through the linear sliding of the slide 94, the chromatographic columns inside each clamping mechanism 10 can be moved to the column taking port 6. Since the linear displacement mechanism 9 can adjust the movement of the chromatographic column to make it reach the taking port, and during its movement, The second motor 81 can also be used to drive the movable ring 82 to rotate. By rotating the movable ring 82, the position of each linear displacement mechanism 9 can be replaced. It can be seen that during use, the device can first clamp and position the chromatographic column through each clamping mechanism 10, and when the chromatographic column needs to be taken and placed, the linear displacement mechanism 9 and the rotating mechanism 8 can be used to flexibly adjust each chromatographic column to move to the column taking port 6. In addition, the setting of the encoder can accurately control the number of rotations of the output shafts of the first motor 1033, the second motor 81 and the third motor 92, so that the device can extremely accurately adjust each chromatographic column to align with the column taking port 6. Obviously, the device only needs to use one column taking port 6 to assist in taking and placing all chromatographic columns, which can greatly improve the overall convenience of the device, effectively avoid the temperature imbalance of the chromatographic column, and thus significantly improve the accuracy of the detection; By cleverly arranging the housing 3, water can be added to the interior of the housing 3 during use, and by starting the operation of the electric heating wire 83, the water inside the housing 3 can be heated. After the water is heated, the chromatographic column can be preheated, which can prompt the chromatographic column to heat up quickly and evenly. In addition, the hot water can not only assist in quickly and stably raising the temperature, but also has a fairly uniform heat preservation performance, which can effectively avoid the temperature imbalance of the chromatographic column. At the same time, when taking out the column, the sealing cover 7 can be twisted open to open the column taking port 6. Through the coordinated cooperation of the rotating mechanism 8, the clamping mechanism 10 and the linear displacement mechanism 9, the chromatographic column can be removed from the interior of the column taking port 6, which can significantly improve the convenience of the overall device during use. After use, loosen the hand-tightening bolt to move it out of the limiting hole 15, and then open the sealing cover 5 and the sealing cover 7 of the drain pipe 12 to discharge the water. At the same time, the interior of the housing 3 can also be opened for convenient inspection and maintenance. By setting the clamping mechanism 10, the chromatographic column can be placed between the inner sides of the clamping plate 104 during use of the device. In view of the setting of the elastic seat 102, the limit spring 1022 inside the mounting frame 1021 provides elastic force, and the limit spring 1022 resists the clamping plate 104 and moves inward, so that the clamping plate 104 can assist in stably clamping and positioning the chromatographic column. With this setting of the clamping mechanism 10, multiple chromatographic columns can be stably installed in the interior of the casing 3. When the chromatographic column needs to be taken out, the chromatographic column can be moved to the column taking port 6 through the cooperation of the linear displacement mechanism 9 and the rotation mechanism 8. At this time, the first motor 1033 is started to run. During this period, due to the movement of the ball bearing The inner side of 105 is fitted and connected to the chromatographic column, and the inner side of the driving wheel 1032 is also fitted and connected to the outer surface of the chromatographic column. At this time, by starting the first motor 1033, the first motor 1033 can drive the driving wheel 1032 located at the upper end to rotate. Since the inner side of the driving wheel 1032 is fitted and connected to the chromatographic column, as the driving wheel 1032 squeezes and drives the chromatographic column, the chromatographic column can reduce the friction on the outer surface of the chromatographic column through the rolling of the driving wheel 1032 and the ball 105, so that the chromatographic column can be quickly and stably removed from the column removal port 6, so that the device can take out the chromatographic column from the inside of the box body 3 without opening the sealed box cover 5, which can greatly improve the overall ease of use of the device.

[0026] The above are all preferred embodiments of the present application, and the protection scope of the present application is not limited thereto. Therefore, any equivalent changes made according to the structure, shape, and principle of the present application should be included in the protection scope of the present application.

Claims

1. A column temperature box capable of independently taking in and placing a single set of chromatographic columns, comprising a ring seat (1), a support leg (2) fixedly mounted on the top of the ring seat (1), a box body (3) fixedly mounted on the top of the support leg (2), a hinge (4) fixedly mounted on the upper end of one side of the box body (3), a sealed box cover (5) hingedly connected to the box body (3) through the hinge (4), a column taking port (6) being provided on one side of the top of the sealed box cover (5), a sealing cover (7) being connected to the inner thread of the column taking port (6), a rotating mechanism (8) fixedly mounted on the bottom of the ring seat (1), a linear displacement mechanism (9) fixedly mounted on the top of the rotating mechanism (8) at equal intervals, a clamping mechanism (10) fixedly connected to the top of the linear displacement mechanism (9) at equal intervals in a linear arrangement, a chromatographic column being clamped inside the clamping mechanism (10), a reserved housing (11) fixedly mounted on the middle of the front side of the box body (3), and a temperature sensor being arranged inside the box body (3); The clamping mechanism (10) comprises a fixed seat (101), the fixed seat (101) being fixedly mounted at equal intervals on the top of the linear displacement mechanism (9), elastic seats (102) being fixedly mounted on both sides of the top of the fixed seat (101), a clamping plate (104) being fixedly mounted on the inner side of the elastic seat (102), and a power assembly (103) being fixedly mounted on the inner side of one elastic seat (102).

2. A column oven capable of independently taking out and placing a single set of chromatographic columns according to claim 1, characterized in that: A drainage pipe (12) is fixedly mounted on the bottom of the box body (3), and a sealing cover (7) is also threadedly connected to the outer end of the drainage pipe (12).

3. A column oven capable of independently taking out and placing a single set of chromatographic columns according to claim 2, characterized in that: A fixing plate (13) is fixedly mounted in the middle of the top right end of the reserved housing (11); a limiting hole (15) is provided in the middle of the front face of the sealed box cover (5); a hand-tightening screw (14) is threadedly connected to the upper end of the fixing plate (13); and a rear end of the hand-tightening screw (14) is inserted into the inside of the limiting hole (15).

4. The column oven capable of independently taking out and placing a single set of chromatographic columns according to claim 1, characterized in that: The elastic seat (102) comprises a mounting frame (1021), the mounting frame (1021) is fixedly mounted on both sides of the top of the fixed seat (101), the interior of the mounting frame (1021) is fixedly mounted with limit springs (1022) at equal intervals, the ends of the limit springs (1022) are fixedly mounted with movable blocks (1023), the movable blocks (1023) are slidably connected to the inner side of the mounting frame (1021), and the clamping plate (104) is fixedly connected to the inner side of the movable block (1023).

5. A column oven capable of independently taking out and placing a single set of chromatographic columns according to claim 4, characterized in that: The power assembly (103) comprises a square groove (1031), wherein the square groove (1031) is provided at the top and the bottom of a mounting frame (1021), and a driving wheel (1032) is rotatably connected inside the square groove (1031). A first motor (1033) is fixedly mounted on an upper end of one side of the mounting frame (1021), and the first motor (1033) is configured as a waterproof motor. An output end of the first motor (1033) passes through the mounting frame (1021) and is fixedly connected to the driving wheel (1032) located at the upper end, and the inner side of the driving wheel (1032) is fitted and connected to a chromatographic column.

6. A column oven capable of independently taking out and placing a single set of chromatographic columns according to claim 5, characterized in that: The overall cross-sectional shape of the clamping plate (104) is V-shaped, the inner side of the clamping plate (104) is fixedly mounted with the clamping plate (104), and the inner side of the clamping plate (104) is rotatably connected with balls (105) at equal intervals.

7. A column oven capable of independently taking out and placing a single set of chromatographic columns according to claim 6, characterized in that: The rotating mechanism (8) comprises a second motor (81), the second motor (81) is fixedly mounted in the middle of the bottom of the box body (3), the output end of the second motor (81) passes through the box body (3) and is fixedly mounted with a movable ring (82), the movable ring (82) is rotatably connected to the bottom of the box body (3), the linear displacement mechanisms (9) are fixedly mounted at equal intervals on the top of the movable ring (82), and the top of the movable ring (82) is located at the gap between each linear displacement mechanism (9) and is fixedly mounted with a heating wire (83), the heating wire (83) being arranged in a spiral shape.

8. The column oven capable of independently taking out and placing a single set of chromatographic columns according to claim 7, characterized in that: Fixed blocks (84) are fixedly installed at equal intervals on the bottom of the movable ring (82), and the bottoms of the fixed blocks (84) are rotatably connected to universal balls (85), and the bottoms of the universal balls (85) are fitted and connected to the bottom of the box (3).

9. A column oven capable of independently taking out and placing a single set of chromatographic columns according to claim 8, characterized in that: The linear displacement mechanism (9) comprises a base (91), the base (91) is arranged in a ring at equal intervals and fixedly mounted on the top of the movable ring (82), a third motor (92) is fixedly mounted on the inner end of the base (91), an output end of the third motor (92) passes through the base (91) and is fixedly mounted with a screw rod (93), the screw rod (93) is rotatably connected to the inside of the base (91), a slide (94) is slidably connected to the top of the base (91), the slide (94) and the screw rod (93) are threadedly connected, and the fixed seat (101) is fixedly mounted on the top of the slide (94) at equal intervals.

10. A column oven capable of independently taking out and placing a single set of chromatographic columns according to claim 9, characterized in that: The overall cross-sectional shape of the lower end of the slide (94) is arranged in a convex shape, and the overall cross-sectional shape of the inner lower end of the base (91) is also arranged in a convex shape. The shaft ends of the first motor (1033), the second motor (81) and the third motor (92) are all equipped with encoders.

Images