Intelligent culture medium preparation system and preparation method

By designing an intelligent culture medium configuration system and using peristaltic pumps and bypass tubes to premix chemicals and keep the ratio confidential, the security risks and leakage of technical secrets existing in traditional configuration devices have been solved, and the confidentiality and safety of the formula have been achieved.

CN119345987APending Publication Date: 2025-01-24RUBBER RES INST CHINESE ACADEMY OF TROPICAL AGRI SCI
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Patent Information

Application Number
CN202411440483.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-10-15
Publication Date
2025-01-24

AI Technical Summary

Technical Problem

Traditional culture medium configuration devices have safety risks and risk of technical secret leakage during drug delivery, especially after the mixing ratio is acquired by external personnel, which may lead to the replication of the real formula and affect competitiveness.

Method used

An intelligent culture medium configuration system was designed, including a mixing chamber, a drug supply unit, an infusion tube, a drug pump unit, a bypass pipe and a drainage unit. The medicine is pre-mixed through a peristaltic pump, and part of the medicine liquid is randomly discharged through the bypass pipe to ensure that the medicine liquid ratio in the mixing chamber is kept confidential. At the same time, the upper and lower alarm limits are set to prevent incorrect dosing through electronic pharmaceutical scales and alarms.

Benefits of technology

The proportion of the real distribution of the real medicine is effectively protected, preventing the formula from being copied, and improving safety and competitiveness. At the same time, the primary liquid of the pharmaceutical agent is randomly discharged to ensure the confidentiality of the pharmaceutical ratio.

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Abstract

The invention discloses an intelligent culture medium preparation system and method, and the system comprises a stirring bin which is used for temporarily storing a culture medium and mixing and preparing a liquid; the medicine supply unit is used for providing various medicine stock solutions and controlling the medicine liquid amount in real time; the liquid conveying pipe is used for being connected with the liquid supply unit and conveying various medicine stock solutions; the medicine pumping unit is used for being connected with an infusion tube, premixing various medicine stock solutions and then conveying the mixed solution into the stirring bin; the bypass pipe is used for randomly discharging part of the stock solution; and the liquid discharging unit is used for discharging residual liquid in the stirring bin and the stock solution randomly conveyed by the bypass pipe. In the invention, in order to protect a real dosage proportion, a chemical stock solution can be randomly discharged through the bypass pipe during dosage, and the stock solution is discharged into the waste box through the seepage pipe, so that the proportion of the chemical solution in the stirring bin is kept confidential and is prevented from being reversely calculated, and the safe use effect is improved.
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Description

Technical Field

[0001] The present invention relates to the technical field of culture medium configuration, and in particular to an intelligent culture medium configuration system and configuration method. Background Art

[0002] Culture medium refers to a nutrient matrix composed of different nutrients for the growth and reproduction of microorganisms, plants or animals (or tissues). It generally contains several major types of substances, such as carbohydrates, nitrogen-containing substances, inorganic salts (including trace elements), vitamins and water. Culture medium is not only the basic substance for providing cell nutrition and promoting cell proliferation, but also the living environment for cell growth and reproduction.

[0003] Traditional culture medium preparation devices deliver various drugs in a certain proportion, and the proportion of various components in the mixed solution can be reversed. This poses a security risk and may lead to the leakage of technical secrets. If the mixing ratio is obtained by outsiders, the real formula may be copied, affecting competitiveness. Summary of the invention

[0004] 1. Technical issues to be solved

[0005] In view of the deficiencies in the prior art, the present invention provides an intelligent culture medium configuration system and configuration method, which solves the problems raised in the above-mentioned background technology.

[0006] (II) Technical solution

[0007] To achieve the above objectives, the present invention is implemented through the following technical solutions: an intelligent culture medium configuration system, comprising:

[0008] A stirring chamber is used for temporarily storing the culture medium and mixing the liquid;

[0009] The drug supply unit provides various drug concentrates and can control the amount of drug solution in real time;

[0010] Infusion tube, used to connect the liquid supply unit to transport various pharmaceutical solutions;

[0011] The medicine pump unit is used to connect with the infusion tube to pre-mix various medicine stock solutions, and then transport the mixed solution to the mixing chamber;

[0012] Bypass pipe, used to discharge part of the original liquid randomly;

[0013] The liquid discharge unit is used to discharge the residual liquid inside the mixing chamber and the original liquid randomly transported by the bypass pipe.

[0014] Preferably, the drug supply unit includes an electronic medicine scale, a medicine barrel, a warning light, and an alarm. The electronic medicine scale monitors the weight of the medicine barrel in real time, and the end of the infusion tube is connected to the medicine barrel. After setting the alarm upper limit and lower limit, the current alarm value calls a random value between the upper limit and the lower limit. The electronic medicine scale will alarm when the weighing value is less than the current alarm value, and the corresponding electronic lock on the medicine box door will control the corresponding medicine box door to open, and the corresponding warning light will light up to prevent incorrect drug addition. After the drug addition is completed, the alarm value will re-call a new random value as the next alarm value.

[0015] Preferably, the medicine pump unit includes a controller, a peristaltic pump, a liquid collector, a medicine delivery pump body and a medicine delivery tube, the controller is used to control the operation of the entire system, the peristaltic pump is used to transfer the raw liquid inside the infusion tube, the liquid collector is connected to multiple infusion tubes for pre-mixing multiple raw liquids, and the medicine delivery pump body is used to extract the mixed liquid inside the liquid collector so that the mixed liquid is discharged into the stirring chamber through the medicine delivery tube.

[0016] Preferably, a cleaning unit is also included. The cleaning unit is an external structure for cleaning the inside of the mixing chamber. The cleaning unit includes a cleaning pipe and an ultrasonic liquid level sensor arranged inside the mixing chamber. When the machine is turned on, the liquid level will be detected by the ultrasonic liquid level sensor. If it is not 0, if cleaning is not required, the prepared agent will be selected in the interface of the control panel. If cleaning is required, automatic cleaning will be performed, and cleaning liquid will be supplied from an external water source. The cleaning liquid enters the mixing chamber through the cleaning pipe. If manual cleaning is selected, the drainage and cleaning actions will be performed manually.

[0017] Preferably, a GPS locator is also included to locate the position of the detection instrument. When the position of the detection instrument is different from the authorized position, the machine stops working. By monitoring the position of the equipment in real time, the equipment can be prevented from operating in unauthorized areas, reducing the risk of theft or misuse, and certain pharmaceutical ingredients can be calculated and fine-tuned according to the latitude.

[0018] Preferably, it also includes a pH meter and a stirring unit. After the liquid preparation is completed, the pH meter is used to automatically calibrate the pH value; the medicine barrel includes a pH barrel, and the sodium hydroxide and hydrochloric acid solutions inside the pH barrel are used to prepare the acid and base of the medicine, and the stirring unit is used to stir the mixed liquid medicine inside the stirring bin.

[0019] Preferably, it also includes a liquid outlet pipe and a control valve, wherein the liquid outlet pipe is connected to the stirring chamber and is used to discharge the finished liquid.

[0020] A method for configuring an intelligent culture medium comprises the following steps:

[0021] S1. Start the medicine pump unit to pump the medicine stock solution in the medicine supply unit into the mixing chamber through the infusion tube;

[0022] S2. The bypass pipe on the delivery pipe randomly discharges a portion of the drug concentrate delivered by the drug supply unit, and allows part of the drug concentrate to enter the liquid discharge unit, ensuring that the drug liquid ratio inside the mixing chamber is kept confidential, preventing reverse calculation, and improving the safety of use;

[0023] S3, start the stirring unit to mix and stir the medicine inside the stirring chamber and complete the liquid preparation work;

[0024] S4. After the liquid preparation is completed, the pH value is automatically calibrated using a pH meter; the reagent barrel includes a pH barrel, and the sodium hydroxide and hydrochloric acid solutions inside the pH barrel are used to configure the acid and base of the reagent, and the stirring unit is started again to stir the mixed liquid inside the stirring chamber, and the preset pH value is aligned by titration while stirring.

[0025] S5. After the liquid preparation is completed, the finished liquid is discharged through the liquid outlet pipe and the control valve;

[0026] S6. Select Clean on the control panel interface to clean the mixing chamber.

[0027] Preferably, during the liquid preparation process of step S1, an upper limit and a lower limit of the alarm are set, and the current alarm value calls a random value between the upper limit and the lower limit. The electronic scale of the medicine will alarm when the weighing value is less than the current alarm value, and the corresponding electronic lock on the medicine box door will control the corresponding medicine box door to open, and the corresponding warning light will light up to prevent incorrect drug addition. After the drug addition is completed, the alarm value will re-call a new random value as the next alarm value.

[0028] Preferably, the specific operation steps of S6 are: select cleaning on the interface of the control panel. If automatic cleaning is selected, automatic cleaning is performed, and the external water source supplies cleaning liquid, and the cleaning liquid enters the mixing chamber through the cleaning pipe. If manual cleaning is selected, the drainage and cleaning actions are performed manually.

[0029] (III) Beneficial effects

[0030] The present invention provides an intelligent culture medium configuration system and configuration method, which have the following beneficial effects:

[0031] 1. In the present invention, the medicines in multiple medicine barrels are pumped into a liquid collector through a peristaltic pump, and then the pre-mixed medicines are pumped into the mixing chamber through the pump body. In order to protect the actual dispensing ratio, the medicine stock solution will be randomly discharged through the bypass pipe during dispensing, and the stock solution will be discharged into the waste box through the seepage pipe. In this way, the medicine liquid ratio in the mixing chamber is kept confidential, which can prevent reverse calculation and improve the safety of use.

[0032] 2. In the present invention, after setting the alarm upper limit and lower limit, the current alarm value calls a random value between the upper limit and the lower limit, and the electronic scale for medicine alarms when the weighing value is less than the current alarm value. After the addition of medicine is completed, the alarm value re-calls a new random value as the next alarm value. When the electronic scale for medicine detects that the weight of the medicine barrel is a random value between the upper limit and the lower limit, the alarm sounds an alarm, and the corresponding electronic lock on the medicine box door will control the corresponding medicine box door to open, and the corresponding warning light will light up to prevent incorrect addition of medicine. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] Figure 1 A structural diagram of an intelligent culture medium configuration system proposed by the present invention;

[0034] Figure 2 This is a structural diagram of a drug supply unit of an intelligent culture medium configuration system proposed by the present invention;

[0035] Figure 3 This is a structural diagram of the pump unit of the intelligent culture medium configuration system proposed in the present invention. DETAILED DESCRIPTION

[0036] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0037] See also Figures 1 to 3 The present invention provides a technical solution: an intelligent culture medium configuration system, comprising:

[0038] A stirring chamber is used for temporarily storing the culture medium and mixing the liquid;

[0039] The drug supply unit provides various drug concentrates and can control the amount of drug solution in real time;

[0040] Infusion tube, used to connect the liquid supply unit to transport various pharmaceutical solutions;

[0041] The medicine pump unit is used to connect with the infusion tube to pre-mix various medicine stock solutions, and then transport the mixed solution to the mixing chamber;

[0042] Bypass pipe, used to discharge part of the original liquid randomly;

[0043] The liquid discharge unit is used to discharge the residual liquid inside the mixing chamber and the original liquid randomly transported by the bypass pipe.

[0044] The medicine supply unit includes an electronic medicine scale, a medicine barrel, a warning light, and an alarm. The electronic medicine scale monitors the weight of the medicine barrel in real time, and the end of the infusion tube is connected to the medicine barrel. After setting the alarm upper and lower limits, the current alarm value calls a random value between the upper and lower limits. The electronic medicine scale will alarm when the weighing value is less than the current alarm value, and the corresponding electronic lock on the medicine box door will control the corresponding medicine box door to open, and the corresponding warning light will light up to prevent incorrect drug addition. After the drug addition is completed, the alarm value will re-call a new random value as the next alarm value.

[0045] The medicine pump unit includes a controller, a peristaltic pump, a liquid collector, a medicine delivery pump body and a medicine delivery tube. The controller is used to control the operation of the entire system. The peristaltic pump is used to transfer the raw liquid inside the infusion tube. The liquid collector is connected to multiple infusion tubes and is used to pre-mix multiple raw liquids. The medicine delivery pump body is used to extract the mixed liquid inside the liquid collector, so that the mixed liquid is discharged into the mixing chamber through the medicine delivery tube.

[0046] It also includes a cleaning unit, which is an external structure for cleaning the inside of the mixing chamber. The cleaning unit includes a cleaning pipe and an ultrasonic liquid level sensor arranged inside the mixing chamber. When the machine is turned on, the liquid level will be detected by the ultrasonic liquid level sensor. If it is not 0, if cleaning is not required, the prepared agent will be selected in the interface of the control panel. If cleaning is required, automatic cleaning will be performed if automatic cleaning is required. The external water source supplies the cleaning liquid, and the cleaning liquid enters the mixing chamber through the cleaning pipe. If manual cleaning is selected, the liquid is drained and cleaned manually.

[0047] It also includes a GPS locator to locate the detection instrument. When the detection instrument is in a different position than the authorized position, the machine stops working. By monitoring the location of the equipment in real time, it can prevent the equipment from operating in unauthorized areas, reduce the risk of theft or misuse, and can fine-tune certain pharmaceutical ingredients based on the latitude and longitude calculations.

[0048] It also includes a pH meter and a stirring unit. After the liquid preparation is completed, the pH meter is used to automatically calibrate the pH value; the reagent barrel includes a pH barrel, and the sodium hydroxide and hydrochloric acid solutions inside the pH barrel are used to configure the acid and alkali of the reagent. The stirring unit is used to stir the mixed liquid inside the stirring bin.

[0049] It also includes a liquid outlet pipe and a control valve. The liquid outlet pipe is connected to the stirring chamber and is used to discharge the finished product liquid.

[0050] A method for configuring an intelligent culture medium comprises the following steps:

[0051] S1. Start the medicine pump unit to pump the medicine stock solution in the medicine supply unit into the mixing chamber through the infusion tube;

[0052] S2. The bypass pipe on the delivery pipe randomly discharges a portion of the drug concentrate delivered by the drug supply unit, and allows part of the drug concentrate to enter the liquid discharge unit, ensuring that the drug liquid ratio inside the mixing chamber is kept confidential, preventing reverse calculation, and improving the safety of use;

[0053] S3, start the stirring unit to mix and stir the medicine inside the stirring chamber and complete the liquid preparation work;

[0054] S4. After the liquid preparation is completed, the pH meter is used to automatically calibrate the pH value; the reagent barrel includes a pH barrel, and the sodium hydroxide and hydrochloric acid solutions in the pH barrel are used to configure the acid and base of the reagent, and the stirring unit is started again to stir the mixed liquid in the stirring chamber, and the preset pH value is aligned by titration while stirring.

[0055] S5. After the liquid preparation is completed, the finished liquid is discharged through the liquid outlet pipe and the control valve;

[0056] S6. Select Clean on the control panel interface to clean the mixing chamber.

[0057] During the liquid preparation process of step S1, the alarm upper limit and lower limit are set. The current alarm value calls a random value between the upper limit and the lower limit. The electronic scale of the medicine will alarm when the weighing value is less than the current alarm value, and the corresponding electronic lock on the medicine box door will control the corresponding medicine box door to open, and the corresponding warning light will light up to prevent incorrect drug addition. After the drug addition is completed, the alarm value will re-call a new random value as the next alarm value.

[0058] The specific operation steps of S6 are: select cleaning on the interface of the control panel. If automatic cleaning is selected, automatic cleaning will be performed, and the external water source will supply the cleaning liquid, which will enter the mixing chamber through the cleaning pipe. If manual cleaning is selected, the drainage and cleaning actions will be performed manually.

[0059] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above embodiments. The above embodiments and descriptions are only preferred examples of the present invention and are not intended to limit the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. An intelligent culture medium configuration system, characterized in that: include: A stirring chamber is used for temporarily storing the culture medium and mixing the liquid; The drug supply unit provides various drug concentrates and can control the amount of drug solution in real time; Infusion tube, used to connect the liquid supply unit to transport various pharmaceutical solutions; The medicine pump unit is used to connect with the infusion tube to pre-mix various medicine stock solutions, and then transport the mixed solution to the mixing chamber; Bypass pipe, used to discharge part of the original liquid randomly; The liquid discharge unit is used to discharge the residual liquid inside the mixing chamber and the original liquid randomly transported by the bypass pipe.

2. An intelligent culture medium configuration system according to claim 1, characterized in that: The medicine supply unit includes an electronic medicine scale, a medicine barrel, a warning light, and an alarm. The electronic medicine scale monitors the weight of the medicine barrel in real time, and the end of the infusion tube is connected to the medicine barrel. After setting the alarm upper limit and lower limit, the current alarm value calls a random value between the upper limit and the lower limit. The electronic medicine scale will alarm when the weighing value is less than the current alarm value, and the corresponding electronic lock on the medicine box door will control the corresponding medicine box door to open, and the corresponding warning light will light up to prevent incorrect drug addition. After the drug addition is completed, the alarm value will re-call a new random value as the next alarm value.

3. The intelligent culture medium configuration system according to claim 1, characterized in that: The medicine pump unit includes a controller, a peristaltic pump, a liquid collector, a medicine delivery pump body and a medicine delivery tube. The controller is used to control the operation of the entire system. The peristaltic pump is used to transfer the raw liquid inside the infusion tube. The liquid collector is connected to multiple infusion tubes and is used to pre-mix multiple raw liquids. The medicine delivery pump body is used to extract the mixed liquid inside the liquid collector so that the mixed liquid is discharged into the stirring chamber through the medicine delivery tube.

4. The intelligent culture medium configuration system according to claim 1, characterized in that: It also includes a cleaning unit, which is an external structure for cleaning the inside of the mixing chamber. The cleaning unit includes a cleaning pipe and an ultrasonic liquid level sensor arranged inside the mixing chamber. When the machine is turned on, the liquid level will be detected by the ultrasonic liquid level sensor. If it is not 0, if cleaning is not required, the prepared agent will be selected in the interface of the control panel. If cleaning is required, automatic cleaning will be performed if automatic cleaning is required. The external water source supplies the cleaning liquid, and the cleaning liquid enters the mixing chamber through the cleaning pipe. If manual cleaning is selected, the liquid is drained and cleaned manually.

5. The intelligent culture medium configuration system according to claim 1, characterized in that: It also includes a GPS locator to locate the location of the testing instrument. When the location of the testing instrument is different from the authorized location, the machine stops working. By monitoring the location of the equipment in real time, it can prevent the equipment from operating in unauthorized areas, reduce the risk of theft or misuse, and can calculate and fine-tune certain pharmaceutical ingredients based on the latitude.

6. The intelligent culture medium configuration system according to claim 1, characterized in that: It also includes a pH meter and a stirring unit. After the liquid preparation is completed, the pH meter is used to automatically calibrate the pH value; the medicine barrel includes a pH barrel, and the sodium hydroxide and hydrochloric acid solutions inside the pH barrel are used to prepare the acid and alkali of the medicine, and the stirring unit is used to stir the mixed liquid medicine inside the stirring bin.

7. The intelligent culture medium configuration system according to claim 1, characterized in that: It also includes a liquid outlet pipe and a control valve. The liquid outlet pipe is connected to the stirring chamber and is used to discharge the finished liquid.

8. A method for configuring an intelligent culture medium, characterized in that: The following steps are involved: S1. Start the medicine pump unit to pump the medicine stock solution in the medicine supply unit into the mixing chamber through the infusion tube; S2. The bypass pipe on the delivery pipe randomly discharges a portion of the drug concentrate delivered by the drug supply unit, and allows part of the drug concentrate to enter the liquid discharge unit, ensuring that the drug liquid ratio inside the mixing chamber is kept confidential, preventing reverse calculation, and improving the safety of use; S3, start the stirring unit to mix and stir the medicine inside the stirring chamber and complete the liquid preparation work; S4. After the liquid preparation is completed, the pH value is automatically calibrated using a pH meter; the reagent barrel includes a pH barrel, and the sodium hydroxide and hydrochloric acid solutions inside the pH barrel are used to configure the acid and base of the reagent, and the stirring unit is started again to stir the mixed liquid inside the stirring chamber, and the preset pH value is aligned by titration while stirring. S5. After the liquid preparation is completed, the finished liquid is discharged through the liquid outlet pipe and the control valve; S6. Select Clean on the control panel interface to clean the mixing chamber.

9. A smart culture medium configuration method according to claim 8, characterized in that: During the liquid preparation process of step S1, the alarm upper limit and lower limit are set. The current alarm value calls a random value between the upper limit and the lower limit. The electronic scale of the medicine will alarm when the weighing value is less than the current alarm value, and the corresponding electronic lock on the medicine box door will control the corresponding medicine box door to open, and the corresponding warning light will light up to prevent incorrect drug addition. After the drug addition is completed, the alarm value will re-call a new random value as the next alarm value.

10. The method for configuring a smart culture medium according to claim 8, characterized in that: The specific operation steps of S6 are: select cleaning on the interface of the control panel. If automatic cleaning is selected, automatic cleaning will be performed, and the external water source will supply the cleaning liquid, which will enter the mixing chamber through the cleaning pipe. If manual cleaning is selected, the drainage and cleaning actions will be performed manually.