Extraction and injection integrated hydrogel injector and injection method
By designing a hydrogel syringe containing multiple syringes and position-changing valves, combined with the pre-initiation and defoaming functions of the hydrogel pretreatment device, the integration of extraction and injection and hydrogel removal in the prior art are solved. The problem of difficulty in bubbles has achieved safer and more efficient joint cartilage repair operations.
Patent Information
- Application Number
- CN202411490435.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-24
- Publication Date
- 2025-02-07
AI Technical Summary
The prior art cannot integrate extraction and injection, and cannot perform defoaming operations on the hydrogel, resulting in the pre-incidence of sol, and bubbles enter the articular cartilage, affecting the treatment effect.
A hydrogel syringe integrated extraction and injection is designed, including multiple syringes and positioning valves, and the hydrogel is pre-initiated and defoamed through a hydrogel pretreatment device, including UV lamps and defoamed devices. Remove air bubbles from the hydrogel.
The integrated operation of extraction and injection is achieved, the surgical process is simplified, the risk of injury is reduced, and the therapeutic effect of the hydrogel is improved through the defoaming operation.
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Figure CN119386318A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of hydrogel injection, and in particular to a hydrogel syringe and an injection method that integrates extraction and injection. Background Art
[0002] Articular cartilage defects and degeneration caused by trauma, inflammation or aging are very common. Cartilage damage promotes the release of proinflammatory factors, increases vascular permeability in the synovium, and allows water and biomacromolecules in the blood vessels to penetrate into the articular cartilage chamber, forming joint effusions. The increase in joint effusions aggravates joint inflammation, causes joint swelling and pain, affects joint movement, and seriously affects patients' daily lives. In recent years, biocompatible materials used to fill and repair articular cartilage defects have become a research hotspot for the treatment of arthritis, which is of great significance for improving the effect of treating cartilage damage and reducing treatment costs.
[0003] Hydrogel has a stable three-dimensional network structure, high water content, and biocompatibility. This structure is similar to the extracellular matrix. After the hydrogel is filled in the gap of the defective articular cartilage, it can serve as a supporting structure to fix the cells in place, provide a three-dimensional growth environment for chondrocytes, and promote the regeneration of defective chondrocytes. This three-dimensional environment allows cells to be evenly distributed throughout the scaffold at a high density. At the same time, this three-dimensional structure can also stimulate chondrocytes and promote the regeneration and proliferation of cartilage. In addition, hydrogel can also be mixed with antibacterial, growth factor and other agents to encapsulate, transport and controllably release the agents, so hydrogel can be used to repair articular cartilage.
[0004] After the sol is injected into the articular cartilage defect, ultraviolet (UV) light irradiation is often required to cause a cross-linking reaction to occur, and the liquid sol is converted into a solid gel. A Chinese patent with publication number CN114177495A discloses a hydrogel syringe and an injection method thereof, and the hydrogel is pre-cured to improve its gelation rate and cross-linking strength. A Chinese patent with publication number CN109758642A discloses a hydrogel injection cross-linking device, which pre-cures the hydrogel at the injection needle by connecting the optical fiber of the light source to improve the degree of cross-linking. However, the sol is relatively viscous, and bubbles are easily generated and difficult to remove during the sol absorption process. Simple pre-curing without de-bubble operation will cause uneven pre-initiation of the sol, and bubbles will be injected into the articular cartilage at the same time, thereby affecting the therapeutic effect of the gel.
[0005] In addition, before injecting hydrogel to repair articular cartilage, the joint effusion needs to be extracted and then the hydrogel can be injected. The two existing technologies can only perform hydrogel injection and need to be used together with the extraction device. The two devices are used alternately during the operation. Multiple operations will increase the difficulty of the operation and increase the risk of secondary damage to the articular cartilage. Summary of the invention
[0006] Purpose of the invention: In view of the shortcomings of the prior art that it is impossible to integrate extraction and injection and to perform defoaming operations on hydrogels, the present invention provides a hydrogel syringe and injection method that integrates extraction and injection.
[0007] Technical solution: To solve the above problems, the present invention adopts an extraction and injection integrated hydrogel syringe, comprising a housing, a shift valve, a first syringe for extracting liquid, a second syringe for injecting hydrogel, a shift control device, and a hydrogel pretreatment device. The syringes of the first syringe and the second syringe are fixed in the housing, and the injection end of the first syringe is connected to the shift valve; one end of the hydrogel pretreatment device is connected to the injection end of the second syringe, and the other end is connected to the shift valve. The hydrogel pretreatment device includes a UV lamp and a defoaming device for puncturing bubbles;
[0008] An extraction channel, an injection channel and an exhaust channel are arranged in the shift valve. A needle is connected to the bottom of the shift valve, and the needle is connected to the outlets of the extraction channel and the injection channel. The shift control device is used to change the position of the shift valve so that the first syringe and the second syringe are connected to different channels.
[0009] Furthermore, the shift valve comprises an annular frame, a top plate, a rotating plate, and a bottom plate. Two positioning devices are symmetrically arranged in the annular frame. The positioning device comprises a spring and a ball. The upper end of the spring abuts against the top surface of the annular frame, and the lower end of the spring is connected to the ball. The outer diameter of the top plate is smaller than the inner diameter of the annular frame. The ball is located outside the top plate. Two connecting holes are respectively used to connect with the first syringe and the hydrogel pretreatment device. The rotating plate is provided with an extraction hole, an injection hole and four positioning holes. The cross section of the injection hole is arc-shaped. The bottom plate is provided with an exhaust hole and an output hole connected to the needle.
[0010] The connecting hole, extraction hole, and output hole are connected to form an extraction channel, the connecting hole, injection hole, and output hole are connected to form an injection channel, and the connecting hole, injection hole, and exhaust hole are connected to form an exhaust channel; the annular frame, top plate, and bottom plate are fixed in the outer shell, and the shift control device is used to drive the rotating plate to rotate so that the ball rolling ball falls into the corresponding positioning hole, so that the first syringe and the second syringe are connected to different channels.
[0011] Furthermore, the shift control device includes a reversing knob, a first gear coaxially arranged with the reversing knob, a second gear meshing with the first gear, a transmission shaft coaxially arranged with the second gear, and a reversing valve core connected to the transmission shaft. An opening is provided on the outer shell for the reversing knob to extend out, and the reversing valve core is installed at the center position of the rotating plate to drive the rotating plate to rotate.
[0012] Furthermore, the hydrogel pretreatment device also includes a shell, a connector arranged on the top of the shell, a glass cover, a battery device, and a battery switch, the connector is connected to the injection end of the second syringe, the UV lamp, the glass cover, and the battery device are fixed in the shell, the battery device is used to power the UV lamp, the battery switch is used to control the battery device, and an opening is opened on the shell for the battery switch to extend; a flow channel for the hydrogel to pass through is provided in the shell, the UV lamp is annular and arranged around the flow channel, the glass cover is arranged between the UV lamp and the flow channel to prevent the UV lamp from directly contacting the hydrogel, the debubbling device is located below the UV lamp, and a cone head cavity is provided at the bottom of the debubbling device, and the cone head cavity is connected to the shift valve.
[0013] Furthermore, a propeller is provided in the shell, and the propeller is located in the flow channel. When the hydrogel flows through the propeller, the hydrogel drives the propeller to rotate to increase the exposed area of the hydrogel.
[0014] Furthermore, the degassing device comprises a circle of blades distributed in a circumferential manner, and the tops of the blades are in the shape of blades for piercing bubbles in the hydrogel.
[0015] Furthermore, the shell includes a shell body and an opening and closing cover, the first syringe and the second syringe are fixed on the shell body, and the shell body is also provided with an opening of the same shape as the opening and closing cover, and one side of the opening and closing cover is installed in the opening through a rotating connecting piece to achieve opening and closing; the outer side of the upper part of the opening and closing cover is provided with a first slider for controlling the movement of the injection rod of the first syringe and a second slider for controlling the movement of the injection rod of the second syringe.
[0016] Furthermore, raised hand-held ends are provided on both sides of the upper part of the shell body, and a suspension arm for hanging is provided on the top of the shell body; and the lower part of the opening and closing cover is made of transparent material.
[0017] Furthermore, a first groove and a second groove are provided on the upper part of the opening and closing cover, the first slider slides along the first groove, and the second slider slides along the second groove; the first slider is connected to the injection rod of the first syringe through a first U-shaped fixing clip, and the second slider is connected to the injection rod of the second syringe through a second U-shaped fixing clip.
[0018] The present invention also provides an injection method of the hydrogel syringe, comprising the following steps:
[0019] Step 1, adjusting the transposition control device so that the first syringe is connected to the extraction channel to absorb the liquid;
[0020] Step 2, adjusting the transposition control device so that the second syringe is connected to the exhaust channel to exhaust, and when the hydrogel flows out of the exhaust channel, stop exhausting;
[0021] Step 3: adjust the transposition control device to connect the second syringe to the injection channel to perform hydrogel injection.
[0022] Beneficial effects: Compared with the prior art, the present invention has the following significant advantages: (1) by providing multiple syringes and shift valves, extraction and injection are integrated, and there is no need to replace different devices for extraction and injection, which simplifies the operation and reduces the risk of injury caused by frequent operation; (2) the hydrogel is pre-triggered and defoamed by the hydrogel pretreatment device, which effectively removes the bubbles in the hydrogel and improves the therapeutic effect of the hydrogel. BRIEF DESCRIPTION OF THE DRAWINGS
[0023] Figure 1 It is a schematic diagram of the overall structure of the hydrogel syringe of the present invention;
[0024] Figure 2 It is a front view of the hydrogel syringe of the present invention;
[0025] Figure 3 It is a front view of the hydrogel syringe of the present invention with the opening and closing cover opened;
[0026] Figure 4 This is a schematic diagram of the back structure of the hydrogel syringe of the present invention;
[0027] Figure 5 It is a schematic diagram of the structure of the syringe and the transposition control device of the present invention;
[0028] Figure 6 for Figure 1 A schematic diagram of the enlarged structure in the middle;
[0029] Figure 7 This is a schematic diagram of the structure of the hydrogel syringe of the present invention after the outer shell is removed;
[0030] Figure 8 This is a front view of the hydrogel syringe of the present invention after the outer shell is removed;
[0031] Fig. 9 It is a cross-sectional view of the hydrogel syringe DD of the present invention;
[0032] Fig.10 It is a schematic diagram of the overall structure of the hydrogel pretreatment device of the present invention;
[0033] Fig.11 This is a schematic diagram of the structure of the hydrogel pretreatment device of the present invention after removing the shell;
[0034] Fig.12 This is a schematic diagram of the structure of the defoaming device of the present invention;
[0035] Fig.13 An exploded view of the shift valve structure of the present invention;
[0036] Fig.14 This is a schematic diagram of the installation structure of the syringe and the shift valve of the present invention;
[0037] Fig.15 It is a schematic diagram of the extraction working state of the shift valve of the present invention;
[0038] Fig.16 This is a schematic diagram of the exhaust working state of the shift valve of the present invention;
[0039] Fig.17 It is a schematic diagram of the injection working state of the shift valve of the present invention. DETAILED DESCRIPTION
[0040] like Figures 1 to 9 As shown, a hydrogel syringe integrated with extraction and injection in this embodiment includes a housing 1, a shift valve 2, a first syringe 31, a second syringe 32, a shift control device 4, and a hydrogel pretreatment device 5. The first syringe 31 is used to extract liquid, and the second syringe 32 is used to inject hydrogel. In this embodiment, the syringe adopts a 5mL detachable GB15810-2019 disposable sterile syringe needle. The syringes of the first syringe 31 and the second syringe 32 are fixed in the housing 1, and the injection end of the first syringe 31 is connected to the shift valve 2. One end of the hydrogel pretreatment device 5 is connected to the injection end of the second syringe 32, and the other end is connected to the shift valve 2. The shift valve 2 is provided with an extraction channel, an injection channel, and an exhaust channel. The bottom of the shift valve 2 is connected to a needle 33, and the needle 33 is connected to the outlet of the extraction channel and the injection channel. The shift control device 4 is used to change the position of the shift valve 2 so that the first syringe 31 and the second syringe 32 are connected to different channels to achieve different functions.
[0041] The housing 1 comprises a housing body 11 and an opening and closing cover 12. A card slot (114, 115, 116, 117) is provided on the inner side of the housing body 11. The syringes of the first syringe 31 and the second syringe 32 are inserted into the card slots to fix them on the housing body 11. Both sides of the upper part of the housing body 11 are provided with raised hand-held ends (111, 112). The hand-held ends are made of TPE material, have a large friction force, and are convenient for operators to hold with one hand. A suspension arm 113 for hanging is provided on the top of the housing body 11. An opening of the same shape as the opening and closing cover 12 is also provided on the housing body 11. One side of the opening and closing cover 12 is installed in the opening through a rotating connector (1217, 1218) to achieve opening and closing. The upper part 121 of the opening and closing cover is provided with a first groove 1211, a second groove 1212, a first slider 1213, and a second slider 1215; the first slider 1213 and the second slider 1215 are located outside the opening and closing cover, and the first slider 1213 slides along the first groove 1211, and the second slider 1215 slides along the second groove 1212. The first slider 1213 is connected to the hand 311 of the first syringe 31 through the first U-shaped fixing clip 1214, and the second slider 1215 is connected to the hand 321 of the second syringe 32 through the second U-shaped fixing clip 1216. By pushing the first slider 1213 and the second slider 1215 up and down, the injection and extraction of the syringe can be controlled. The lower part 122 of the opening and closing cover is made of transparent material, such as PMMA organic glass, transparent ABS plastic, etc., and the transparent material is convenient for observing the working condition of the syringe. When the syringe needs to be replaced, the opening and closing cover 12 can be opened and replaced. In the working state, the opening and closing cover 12 is closed.
[0042] like Figures 10 to 12As shown, the hydrogel pretreatment device 5 includes a shell 59, a connector 52 arranged on the top of the shell, a UV lamp 56, a glass cover 54, a propeller 55, a battery device 57, a battery switch 51, and a defoaming device 58. A mounting plate 53 is provided at the bottom of the shell 59, and the UV lamp 56, the glass cover 54, the propeller 55, and the battery device 57 are fixed on the mounting plate 53. The battery device 57 is used to power the UV lamp 56, and the battery switch 51 is used to control the battery device 57. An opening is provided on the shell 59 for the battery switch 51 to extend out. A flow channel for the hydrogel to pass through is provided in the shell 59. The UV lamp 56 is annular and arranged around the flow channel. The glass cover 54 is arranged between the UV lamp 56 and the flow channel to prevent the UV lamp 56 from directly contacting the hydrogel and causing the hydrogel to adhere to the UV lamp, thereby affecting the irradiation effect. The propeller 55 is located in the flow channel. When the hydrogel flows through the propeller 55, the hydrogel drives the propeller 55 to rotate. The propeller 55 rotates and stirs the hydrogel to increase the exposed area of the hydrogel, thereby increasing the area of the hydrogel irradiated by the UV lamp and improving the pre-initiation effect. The debubbling device 58 is located below the UV lamp 56. The debubbling device 58 includes a circle of blades 582 distributed in a circle. The top of the blade 582 is in the shape of a blade and is used to puncture bubbles in the hydrogel. A cone head cavity 581 is provided at the bottom of the debubbling device 58, and the cone head cavity 581 is connected to the shift valve 2.
[0043] like Fig.13 and Fig.14As shown, the shift valve 2 includes an annular frame 21, a top plate 22, a rotating plate 23, and a bottom plate 24. Two positioning devices are symmetrically arranged in the annular frame 21. The positioning devices include springs (2121, 2112) and round balls (2122, 2111). The upper end of the spring abuts against the inner top surface of the annular frame 21, and the lower end of the spring is connected to the round ball. The outer diameter of the top plate 22 is smaller than the inner diameter of the annular frame 21. The round ball is located outside the top plate 22. The top plate 22 is provided with two connection holes 221 for communicating with the first syringe 31 and a connection hole 222 for connecting with the hydrogel pretreatment device 5. The rotating plate 23 is provided with an extraction hole 235, an injection hole 236 and four positioning holes 231. The cross section of the injection hole 236 is arc-shaped. The bottom plate 24 is provided with an exhaust hole 241 and an output hole 242, and the output hole 242 is connected to the needle 33. The connecting hole 221, the extraction hole 235, and the output hole 242 are connected to form an extraction channel; the connecting hole 222, the injection hole 236, and the output hole 242 are connected to form an injection channel; the connecting hole 222, the injection hole 236, and the exhaust hole 241 are connected to form an exhaust channel. The annular frame 21, the top plate 22, and the bottom plate 24 are fixed in the shell 1. The shell 1, the annular frame 21, and the top plate 22 are all provided with bolt holes (118, 119) with matching positions. The bolts (213, 214) are installed in the bolt holes to fix the annular frame 21, the top plate 22 and the shell. The transposition control device 4 is connected to the rotating plate 23 to drive the rotating plate 23 to rotate, so that the first syringe 31 and the second syringe 32 are connected to different channels.
[0044] like Fig. 9 As shown, the shift control device 4 includes a reversing knob 41, a first gear 42 coaxially arranged with the reversing knob 41, a second gear 43 meshing with the first gear 42, a transmission shaft 44 coaxially arranged with the second gear 43, and a reversing valve core 25 connected with the transmission shaft 44. The reversing knob 41 is marked with numbers "1", "2" and "3", corresponding to the extraction mode, the exhaust mode and the injection mode respectively. The reversing knob 41 is coaxially installed on the connecting shaft 45 with the first gear 42, and an opening is opened on the back of the housing 1 for the reversing knob 41 to extend out. The reversing valve core 25 includes an axis 253 connected with the rotating plate 23, and a sealing ring (251, 252) installed at the connection between the axis 253 and the upper and lower end surfaces of the rotating plate 23. The sealing ring is used to prevent the liquid from flowing out of the valve core during extraction or injection. By rotating the reversing knob 41 to the corresponding working mode, the rotating plate 23 is driven to rotate, and the springs (2121, 2112) push the ball rolling balls (2122, 2111) to fall into the corresponding positioning holes for positioning, so that the corresponding channels are connected.
[0045] When in use, the first syringe 31 is an empty tube, the second syringe 32 is filled with hydrogel, the battery switch 51 is turned on to put the UV lamp in an irradiation state, and the specific injection method includes the following steps:
[0046] Step 1: Rotate the reversing knob 41 to position "1" to drive the rotating plate 23 to rotate so that the connecting hole 221, the extraction hole 235, and the output hole 242 are connected to form an extraction channel. Fig.15 After the injection end of the first syringe 31 is connected to the extraction channel, the first slider 1213 is pushed upward to extract liquid.
[0047] Step 2: Rotate the reversing knob 41 to position "2" to drive the rotating plate 23 to rotate so that the connecting hole 222, the injection hole 236, and the exhaust hole 241 are connected to form an exhaust channel. Fig.16 After the cone head cavity 581 is connected to the exhaust channel, the second slider 1215 is pushed downward to exhaust the air in the second syringe 32, and the exhaust is stopped when the hydrogel flows out of the exhaust channel.
[0048] Step 3, rotate the reversing knob 41 to the gear position "3", drive the rotating plate 23 to rotate so that the connecting hole 222, the injection hole 236, and the output hole 242 are connected to form an injection channel, such as Fig.17 After the second syringe 32 is connected to the injection channel, the second slider 1215 is pushed downward to inject the hydrogel.
[0049] The hydrogel syringe of the present invention realizes the integration of extraction and injection by providing multiple syringes and shift valves, and does not need to replace different devices for extraction and injection, thereby simplifying the operation and reducing the risk of injury caused by frequent operation; the hydrogel is pre-triggered and defoamed by the hydrogel pretreatment device, so that the bubbles in the hydrogel are effectively removed, thereby improving the therapeutic effect of the hydrogel.
Claims
1. A hydrogel syringe integrating extraction and injection, characterized in that: The invention comprises a housing (1), a shift valve (2), a first syringe (31) for extracting liquid, a second syringe (32) for injecting hydrogel, a shift control device (4), and a hydrogel pretreatment device (5); the syringe barrels of the first syringe (31) and the second syringe (32) are fixed in the housing (1); the injection end of the first syringe (31) is connected to the shift valve (2); one end of the hydrogel pretreatment device (5) is connected to the injection end of the second syringe (32), and the other end is connected to the shift valve (2); the hydrogel pretreatment device (5) comprises a UV lamp (56) and a degassing device (58) for puncturing bubbles; An extraction channel, an injection channel, and an exhaust channel are arranged in the shift valve (2). A needle (33) is connected to the bottom of the shift valve (2). The needle (33) is communicated with the outlets of the extraction channel and the injection channel. The shift control device (4) is used to change the position of the shift valve (2) so that the first injector (31) and the second injector (32) are communicated with different channels.
2. The hydrogel syringe according to claim 1, characterized in that: The shift valve (2) comprises an annular frame (21), a top plate (22), a rotating plate (23), and a bottom plate (24); two positioning devices are symmetrically arranged in the annular frame (21); the positioning devices comprise a spring (2121) and a round ball (2122); the upper end of the spring (2121) abuts against the inner top surface of the annular frame (21), and the lower end of the spring (2121) is connected to the round ball (2122); the outer diameter of the top plate (22) is smaller than the inner diameter of the annular frame (21); The ball roller (2122) is located on the outside of the top plate (22), and the top plate (22) is provided with two connection holes for connecting with the first syringe (31) and the hydrogel pretreatment device (5) respectively; the rotating plate (23) is provided with an extraction hole (235), an injection hole (236) and four positioning holes (231), and the cross section of the injection hole (236) is arc-shaped; the bottom plate (24) is provided with an exhaust hole (241) and an output hole (242) connected with the needle (33); The connecting hole, the extraction hole (235) and the output hole (242) are connected to form an extraction channel, the connecting hole, the injection hole (236) and the output hole (242) are connected to form an injection channel, and the connecting hole, the injection hole (236) and the exhaust hole (241) are connected to form an exhaust channel; the annular frame (21), the top plate (22) and the bottom plate (24) are fixed in the housing (1), and the position change control device (4) is used to drive the rotating plate (23) to rotate so that the ball rolling ball (2122) falls into the corresponding positioning hole, so that the first syringe (31) and the second syringe (32) are connected to different channels.
3. The hydrogel syringe according to claim 2, characterized in that: The shift control device (4) comprises a reversing knob (41), a first gear (42) coaxially arranged with the reversing knob (41), a second gear (43) meshing with the first gear (42), a transmission shaft (44) coaxially arranged with the second gear (43), and a reversing valve core (25) connected to the transmission shaft (44); an opening for the reversing knob (41) to extend out is formed on the housing (1); and the reversing valve core (25) is installed at the center position of the rotating plate (23) to drive the rotating plate (23) to rotate.
4. The hydrogel syringe according to claim 1, characterized in that: The hydrogel pretreatment device (5) further comprises a housing (59), a connector (52) arranged on the top of the housing, a glass cover (54), a battery device (57), and a battery switch (51); the connector (52) is connected to the injection end of the second syringe (32); the UV lamp (56), the glass cover (54), and the battery device (57) are fixed in the housing (59); the battery device (57) is used to supply power to the UV lamp (56); the battery switch (51) is used to control the battery device (57); The housing (59) has an opening through which the battery switch (51) extends. The housing (59) is provided with a flow channel through which the hydrogel passes. The UV lamp (56) is annular and arranged around the flow channel. The glass cover (54) is arranged between the UV lamp (56) and the flow channel to prevent the UV lamp (56) from directly contacting the hydrogel. The debubbling device (58) is located below the UV lamp (56). The bottom of the debubbling device (58) is provided with a cone head cavity (581), and the cone head cavity (581) is connected to the shift valve (2).
5. The hydrogel syringe according to claim 4, characterized in that: A propeller (55) is also provided in the housing (59). The propeller (55) is located in the flow channel. When the hydrogel flows through the propeller (55), the hydrogel drives the propeller (55) to rotate to increase the exposed area of the hydrogel.
6. The hydrogel syringe according to claim 1, characterized in that: The debubbling device (58) comprises a circle of blades (582) distributed in a circumferential manner, and the tops of the blades (582) are in the shape of blades and are used to puncture bubbles in the hydrogel.
7. The hydrogel syringe according to claim 1, characterized in that: The housing (1) comprises a housing body (11) and an opening and closing cover (12); a first syringe (31) and a second syringe (32) are fixed on the housing body (11); an opening having the same shape as the opening and closing cover (12) is also provided on the housing body (11); one side of the opening and closing cover (12) is installed in the opening through a rotating connecting piece (1217) to achieve opening and closing; a first slider (1213) for controlling the movement of the injection rod of the first syringe (31) and a second slider (1215) for controlling the movement of the injection rod of the second syringe (32) are provided on the outer side of the upper part of the opening and closing cover (12).
8. The hydrogel syringe according to claim 2, characterized in that: Both sides of the upper part of the shell body (11) are provided with raised hand-held ends, and the top of the shell body (11) is provided with a hanging arm (113) for hanging; the lower part of the opening and closing cover (12) is made of transparent material.
9. The hydrogel syringe according to claim 2, characterized in that: The upper part of the opening and closing cover (12) is provided with a first groove (1211) and a second groove (1212); the first slider (1213) slides along the first groove (1211), and the second slider (1215) slides along the second groove (1212); the first slider (1213) is connected to the injection rod of the first syringe (31) through a first U-shaped fixing clamp (1214), and the second slider (1215) is connected to the injection rod of the second syringe (32) through a second U-shaped fixing clamp (1216).
10. A method for injecting the hydrogel syringe according to any one of claims 1 to 9, characterized in that: The following steps are involved: Step 1: adjusting the position change control device (4) so that the first syringe (31) is connected to the extraction channel to absorb the liquid; Step 2, adjusting the transposition control device (4) so that the second injector (32) is connected to the exhaust channel to exhaust gas, and when the hydrogel flows out of the exhaust channel, the exhaust gas is stopped; Step 3: adjusting the transposition control device (4) to connect the second syringe (32) to the injection channel to perform hydrogel injection.
Citation Information
Patent Citations
Novel hydrogel injection crosslinking device
CN109758642A
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CN114177495A
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