Gastroscope dosing device and method convenient to use

Abstract

The invention discloses a gastroscope dosing device and method convenient to use, and relates to the technical field of medical instruments. The magnetic control capsule gastroscope comprises a magnetic control capsule gastroscope body and a drug delivery capsule, the drug delivery capsule is used for being matched with movement of the magnetic control capsule gastroscope body to directly deliver drugs to the stomach of a patient, the drug delivery capsule comprises a power capsule, and a drug storage capsule is fixedly installed on the side, away from the magnetic control capsule gastroscope body, of the power capsule. The medicine storage capsule is used for storing medicine, the same folding tube is arranged between the magnetic control capsule gastroscope and the power capsule, and a medicine feeding spray head is fixedly installed at the bottom of the medicine storage capsule. By arranging the power assembly, the magnetic control capsule gastroscope is controlled to carry the administration capsule to move to be close to an affected part, then the power assembly is controlled to extrude a medicament, the medicament is directly sprayed out from the medicament spraying micropores under the pressure effect, then the medicament liquid is sprayed to the affected part, and direct administration is achieved; the problem that a traditional capsule gastroscope can only be used for observation and cannot be used for administration is solved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical instruments, and in particular to a convenient-to-use gastroscope medication delivery device and method. Background Art

[0002] Gastroscopy is a common invasive examination and a good way to diagnose gastrointestinal diseases. However, it will cause obvious discomfort during the examination and there are serious complications such as infection, bleeding, and perforation. Painless gastroscopy also has the risk of anesthesia accidents. The magnetically controlled capsule gastroscopy can achieve high visualization of the gastric mucosa due to its accurate control and positioning. The diagnostic accuracy is highly consistent with that of traditional gastroscopy. After examining the stomach, the small intestine can be further examined. It is painless and non-invasive, does not require anesthesia and disinfection, is simple and comfortable, and has lower risks.

[0003] The magnetically controlled capsule gastroscopy system is mainly composed of four parts: a capsule endoscope, an image recorder, a software imaging workstation and a magnetic field control device. The control principle is mainly to set a magnet inside the capsule gastroscopy, and then control the movement trajectory of the capsule gastroscopy in the subject's body through an external magnetic field, that is, to apply a magnetic field around the subject and drive the capsule with a magnetic moment to move in the human digestive system by manipulating the rotation and translation of the magnetic field, so that medical staff can comprehensively observe the gastrointestinal tract from all directions. The main disadvantage of the current magnetically controlled capsule gastroscopy is that it can only provide precise observation and detection functions, but cannot achieve in vivo drug delivery. In order to achieve in vivo drug delivery, the assistance of a traditional endoscope is still required. For this reason, a convenient gastroscopy drug delivery device and method are proposed. Summary of the invention

[0004] The purpose of the present invention is to solve the problem that the main disadvantage of the current magnetically controlled capsule gastroscope is that it can only provide accurate observation and detection functions but cannot achieve in vivo drug delivery. In order to achieve in vivo drug delivery, the assistance of a traditional endoscope is still required. The present invention provides an easy-to-use gastroscope drug delivery device and method.

[0005] In order to achieve the above-mentioned purpose, the present invention specifically adopts the following technical solutions:

[0006] A convenient gastroscope medication device, comprising a magnetically controlled capsule gastroscope and a medication capsule, wherein the medication capsule is used to directly administer medication to a patient's stomach in coordination with the movement of the magnetically controlled capsule gastroscope;

[0007] The drug delivery capsule comprises a power capsule, a drug storage capsule is fixedly installed on one side of the power capsule away from the magnetically controlled capsule gastroscope, the drug storage capsule is used to store medicine, a folding tube is arranged between the magnetically controlled capsule gastroscope and the power capsule, a drug delivery nozzle is fixedly installed on the bottom of the drug storage capsule, a plurality of evenly distributed drug spraying microholes are arranged on the drug delivery nozzle, the drug spraying microholes are all connected with the interior of the drug storage capsule, a sealing partition is fixedly installed inside the drug storage capsule, the sealing partition is located at the junction of the power capsule and the drug storage capsule, and a power component is arranged inside the power capsule;

[0008] The power assembly is used to squeeze the medicine in the medicine storage capsule so that the medicine is sprayed to the outside from the medicine spraying micropores on the drug delivery nozzle. The power assembly includes a micro guide rail arranged inside the power capsule, the micro guide rail is fixedly installed on the top of the sealing partition, one side of the micro guide rail is driven to install an electric slider, a traveling frame is fixedly installed on the side wall of the electric slider, and a power frame is fixedly installed on one end of the traveling frame. A sealing sliding hole is opened on the top of the sealing partition, and the bottom end of the power frame passes through the sealing sliding hole and extends to the inside of the folding tube and is fixedly installed with a medicine pushing plate;

[0009] A first docking plate is fixedly installed on both sides of the medicine storage capsule, a magnetic metal plate is fixedly installed on the side wall of the first docking plate, an outer shell is fixedly installed on the side wall of the first docking plate, and the two magnetic metal plates are respectively located inside the two outer shells. A second docking plate is fixedly installed on both sides of the magnetically controlled capsule gastroscope, and the positions of the two first docking plates correspond to the positions of the two second docking plates respectively. The side walls of the second docking plate are provided with docking grooves that are compatible with the outer shells, and the sides of the docking grooves are provided with docking guide angles. A plurality of evenly distributed limiting rings are fixedly installed inside the folding tube, and a plurality of mutually hinged steering plates are fixedly installed between any two adjacent limiting rings.

[0010] Furthermore, gelatin blocks are fixedly mounted on both ends of the folding tube, and the two gelatin blocks are respectively fixedly mounted on the side walls of the magnetically controlled capsule gastroscope and the power capsule that are close to each other.

[0011] Furthermore, a connecting rope is provided inside the folding tube, and the connecting rope is located inside the plurality of limiting rings. Both ends of the connecting rope respectively pass through both ends of the folding tube and extend to the inside of the two gelatin blocks, and a clamping block is fixedly installed on one end of the connecting rope located inside the gelatin block.

[0012] Furthermore, a first soft rubber shell is fixedly installed on the side where the magnetically controlled capsule gastroscope and the power capsule are close to each other, two ends of the folding tube are respectively fixedly installed inside the two first soft rubber shells, the two gelatin blocks are respectively located inside the two first soft rubber shells, and a plurality of first lifting plates are fixedly installed on the side walls of the first soft rubber shells.

[0013] Furthermore, a plurality of evenly distributed annular reinforcement frames are fixedly mounted on the inner wall of the power capsule, and the micro guide rail is fixedly connected to the plurality of annular reinforcement frames.

[0014] Furthermore, a gelatin film is fixedly mounted on the bottom of the drug storage capsule, and the drug delivery nozzle is located inside the gelatin film.

[0015] Furthermore, a second soft rubber shell is fixedly installed on the bottom of the medicine storage capsule, the gelatin film is located inside the second soft rubber shell, and a plurality of second rubber lifting plates are fixedly installed on the side wall of the second soft rubber shell.

[0016] A gastroenteroscopic drug delivery method based on the drug delivery device of the present invention comprises the following steps:

[0017] S1. Preparation for medication: The patient wears the image recorder and lies on the bed. The medical staff takes the device out of the package, tears off the first soft rubber cover and the second soft rubber cover, and hands the device to the patient to swallow:

[0018] S2. Location of the affected area: Medical staff use an external magnetic field control device to control the movement of the magnetically controlled capsule gastroscope in the patient's stomach, and observe the patient's stomach in real time through the software imaging workstation and the image recorder worn by the patient until the affected area is found:

[0019] S3. Folding of the device: The medical staff controls the magnetically controlled capsule gastroscope and the power capsule to contact each other, and the magnetic metal plate is inserted into the docking groove. The magnetically controlled capsule gastroscope and the power capsule are folded and assembled so that the direction of the magnetically controlled capsule gastroscope camera device is parallel to the direction of the drug delivery nozzle:

[0020] S4. Precise drug delivery: The position and direction of the drug delivery nozzle are precisely controlled by controlling the movement of the magnetically controlled capsule gastroscope. While the magnetically controlled capsule gastroscope is photographing the affected area, the power component squeezes the medicine so that the medicine is sprayed on the affected area under pressure, achieving direct and precise drug delivery:

[0021] S5. Device excretion: After the drug administration is completed, the medical staff controls the magnetically controlled capsule gastroscope to separate from the power capsule, and the gelatin block gradually dissolves in the patient's body, so that the magnetically controlled capsule gastroscope, the folding tube and the drug administration capsule are separated from each other, and the device is decomposed into multiple small parts, which is convenient for the patient to excrete the device later.

[0022] The beneficial effects of the present invention are as follows:

[0023] 1. The present invention sets a power component to control the magnetically controlled capsule gastroscope to carry the drug-delivery capsule and move close to the affected area, and then controls the power component to squeeze the medicine, so that the medicine is directly ejected from each drug-delivery micropore under the action of pressure, and then the drug liquid is sprayed on the affected area to achieve direct drug delivery, thus solving the problem that the traditional capsule gastroscope can only be used for observation but not for drug delivery;

[0024] 2. The present invention provides a folding tube, so that medical staff can control the magnetically controlled capsule gastroscope and the drug-delivery capsule to fold and assemble, so that the direction of the magnetically controlled capsule gastroscope is parallel to the direction of the drug-delivery nozzle. At this time, the position and direction of the drug-delivery nozzle can be accurately controlled by controlling the movement of the magnetically controlled capsule gastroscope. While the magnetically controlled capsule gastroscope is photographing the affected area, the power component is controlled to push out the medicine in the drug storage capsule and spray it on the affected area, so as to achieve accurate drug delivery;

[0025] 3. The present invention provides gelatin blocks so that after the examination and medication are completed, the magnetically controlled capsule gastroscope and the power capsule are separated under the action of gravity, and then the gelatin blocks at both ends of the folding tube are gradually dissolved under the action of the patient's own digestive system, so that the magnetically controlled capsule gastroscope, the folding tube and the medication capsule are separated from each other, and the device is decomposed into multiple small parts, which is convenient for the patient to discharge the device later;

[0026] 4. The present invention provides a connecting rope and a clamping block, so that the clamping blocks at both ends of the connecting rope are respectively located inside the two gelatin blocks. The connecting rope and the clamping block can improve the connection strength between the two ends of the folding tube and the gelatin block. When the folding tube is bent, the clamping block located inside the gelatin block can prevent the gelatin block from directly tearing the rubber surface of the folding tube;

[0027] 5. The present invention provides a first soft rubber shell, so that when the device is taken out of the package, the first rubber sheet is cut first, and the first soft rubber shell is torn off from one side of the magnetically controlled capsule gastroscope and the power capsule, so that the gelatin block is exposed to the outside. The first soft rubber shell can wrap the two gelatin blocks inside for protection, so as to prevent the gelatin blocks from getting damp or debonding prematurely from the magnetically controlled capsule gastroscope, the power capsule and the folding tube;

[0028] 6. The present invention provides an annular reinforcement frame, so that multiple annular reinforcement frames are fixed on the inner wall of the power capsule, which can play a positioning role for the micro-guide rail, improve the connection strength of the micro-guide rail inside the power capsule, and stably install the micro-guide rail on the sealing partition, so that the micro-guide rail can maintain balance during the movement of the electric slider, and prevent the micro-guide rail from shaking and affecting the release of the medicine;

[0029] 7. The present invention provides a gelatin film so that the gelatin film can play a protective role on the drug delivery nozzle. On the one hand, it can prevent dust and bacteria from entering the medicine storage capsule through the drug delivery nozzle and mixing into the medicine before the patient swallows the medicine. On the other hand, it can further prevent the medicine in the medicine storage capsule from leaking out. After the patient swallows the medicine, the gelatin film on the outer surface of the drug delivery nozzle will dissolve within a few minutes after contacting the gastric juice, thereby not hindering the subsequent discharge of the medicine. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention;

[0031] Figure 2 It is a schematic diagram of the three-dimensional structure of the magnetically controlled capsule endoscope of the present invention;

[0032] Figure 3 It is a schematic diagram of the three-dimensional structure of the drug-delivery capsule of the present invention;

[0033] Figure 4 It is a schematic diagram of the three-dimensional structure of the drug delivery nozzle and the hydrolysis membrane of the present invention;

[0034] Figure 5 It is a schematic diagram of the internal three-dimensional structure of the power capsule and the drug storage capsule of the present invention;

[0035] Figure 6 It is a schematic diagram of the three-dimensional structure of the power assembly of the present invention;

[0036] Figure 7 It is a schematic diagram of the three-dimensional structure of the micro guide rail and the power frame of the present invention;

[0037] Figure 8 It is a schematic diagram of the three-dimensional structure of the power capsule, the drug storage capsule and the sealing partition of the present invention;

[0038] Fig. 9 It is a schematic diagram of the internal three-dimensional structure of the folding tube of the present invention;

[0039] Fig.10 The present invention Fig. 9 Schematic diagram of the structure at A in the middle;

[0040] Fig.11 It is a schematic diagram of the three-dimensional structure of the magnetically controlled capsule endoscope and the drug-delivery capsule in a folded state of the present invention;

[0041] Fig.12 It is a schematic flow chart of a gastroenteroscopic drug delivery method of the present invention;

[0042] Figure numerals: 1. Magnetically controlled capsule gastroscope; 2. Power capsule; 3. Drug storage capsule; 4. Folding tube; 5. Drug delivery nozzle; 501. Drug spraying microhole; 6. Sealing partition; 601. Sealing sliding hole; 7. Micro guide rail; 8. Electric slider; 9. Traveling frame; 10. Power frame; 11. Drug pushing plate; 12. First docking plate; 13. Magnetic metal plate; 14. Second docking plate; 1401. Docking groove; 1402. Docking guide angle; 15. Outer shell; 16. Limiting ring; 17. Steering plate; 18. Gelatin block; 19. Connecting rope; 20. Clamping block; 21. First soft rubber shell; 22. First rubber lifting plate; 23. Annular reinforcement frame; 24. Gelatin film; 25. Second soft rubber shell; 26. Second rubber lifting plate. DETAILED DESCRIPTION

[0043] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Generally, the components of the embodiments of the present invention described and shown in the drawings here can be arranged and designed in various different configurations.

[0044] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the invention claimed for protection, but merely represents selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0045] It should be noted that similar reference numerals and letters represent similar items in the following drawings, so once an item is defined in one drawing, it does not need to be further defined and explained in the subsequent drawings. In addition, the terms "first", "second", etc. are only used to distinguish the description and cannot be understood as indicating or implying relative importance.

[0046] In the description of the embodiments of the present invention, it should be noted that the terms "inside", "outside", "upper", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, or are the orientations or positional relationships in which the inventive product is usually placed when used. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0047] like Figures 1 to 12 As shown, a convenient gastroscopic drug delivery device comprises a magnetically controlled capsule gastroscope 1 and a drug delivery capsule, wherein the drug delivery capsule is used to directly deliver drug to the patient's stomach in coordination with the movement of the magnetically controlled capsule gastroscope 1;

[0048] like Figure 1 As shown, the drug-delivery capsule includes a power capsule 2, and a drug storage capsule 3 is fixedly installed on one side of the power capsule 2 away from the magnetically controlled capsule gastroscope 1. The drug storage capsule 3 is used to store medicines. A folding tube 4 is provided between the magnetically controlled capsule gastroscope 1 and the power capsule 2. Figure 8 As shown, a drug delivery nozzle 5 is fixedly installed at the bottom of the drug storage capsule 3, and a plurality of evenly distributed drug spraying micropores 501 are provided on the drug delivery nozzle 5, and the drug spraying micropores 501 are all connected with the interior of the drug storage capsule 3, and a sealing partition 6 is fixedly installed inside the drug storage capsule 3, and the sealing partition 6 is located at the junction of the power capsule 2 and the drug storage capsule 3, and a power component is arranged inside the power capsule 2; specifically, when the convenient gastroscopic drug delivery device is used, the patient first wears the image recorder and lies on the bed, and the medical staff takes the device out of the package and gives it to the patient to drink water and swallow into the stomach, and the medicine inside the drug storage capsule 3 will not leak out of the drug spraying micropores 501 on the drug delivery nozzle 5 in advance under the action of the tension micro guide rail 7, and at this time, the medical staff controls the magnetically controlled capsule gastroscope 1 to move in the patient's stomach through the external magnetic field control device and the controllable magnet inside the magnetically controlled capsule gastroscope 1, and observes the patient's stomach condition in real time through the software imaging workstation and the image recorder worn by the patient until the affected area is found;

[0049] The power assembly is used to squeeze the medicine in the medicine storage capsule 3 so that the medicine is sprayed to the outside from the medicine spraying micro-holes 501 on the drug delivery nozzle 5. Figure 5 , Figure 6 As shown, the power assembly includes a micro guide rail 7 disposed inside the power capsule 2, the micro guide rail 7 is fixedly mounted on the top of the sealing partition 6, an electric slider 8 is driven and mounted on one side of the micro guide rail 7, and a traveling frame 9 is fixedly mounted on the side wall of the electric slider 8, as shown in FIG. Figure 7 As shown, a power frame 10 is fixedly mounted on one end of the traveling frame 9. Figure 8 As shown, a sealing sliding hole 601 is provided on the top of the sealing partition 6. Figure 5As shown, the bottom end of the power frame 10 passes through the sealing slide hole 601 and extends to the inside of the folding tube 4 and is fixedly installed with a medicine pushing plate 11. In this embodiment, the power frame 10 is located at the axial position of the power capsule 2 and the medicine storage capsule 3. A sealing sleeve is provided at the joint between the power frame 10 and the sealing slide hole 601. The medicine pushing plate 11 is made of soft rubber material. The medicine pushing plate 11 fits with the inner wall of the medicine storage capsule 3 to prevent the medicine inside the medicine storage capsule 3 from penetrating into the power capsule 2. Specifically, by setting the power component, the medical staff can control The magnetically controlled capsule gastroscope 1 carries the drug-delivering capsule and moves close to the affected part, and then controls the electric slider 8 inside the power capsule 2 to start sliding along the micro-guide rail 7, thereby driving the power frame 10 to slide in the sealed sliding hole 601 through the traveling frame 9, so that the drug-pushing plate 11 at one end of the power frame 10 squeezes the medicine in the drug storage capsule 3, so that the medicine is directly ejected from each drug-spraying micro-hole 501 under the action of pressure, and then the drug liquid is sprayed on the affected part, realizing direct drug delivery, and solving the problem that the traditional capsule gastroscope can only be used for observation but not for drug delivery;

[0050] like Figure 3 As shown, first docking plates 12 are fixedly installed on both sides of the medicine storage capsule 3, magnetic metal plates 13 are fixedly installed on the side walls of the first docking plates 12, and outer shells 15 are fixedly installed on the side walls of the first docking plates 12. The two magnetic metal plates 13 are respectively located inside the two outer shells 15. Figure 2 As shown, the second docking plates 14 are fixedly installed on both sides of the magnetically controlled capsule gastroscope 1, and the positions of the two first docking plates 12 correspond to the positions of the two second docking plates 14 respectively. The side walls of the second docking plates 14 are provided with docking grooves 1401 adapted to the outer shell 15, and the sides of the docking grooves 1401 are provided with docking guide angles 1402. Fig. 9 , Fig.10As shown, a plurality of evenly distributed limiting rings 16 are fixedly installed inside the folding tube 4, and a plurality of mutually hinged steering plates 17 are fixedly installed between any two adjacent limiting rings 16. In this embodiment, the relative rotation direction of the two adjacent steering plates 17 is on the same vertical plane as the straight line where the first docking plate 12 and the second docking plate 14 are located; specifically, by setting the folding tube 4, when the patient swallows the device, the magnetically controlled capsule gastroscope 1 and the drug-delivery capsule are connected through the folding tube 4, and the magnetically controlled capsule gastroscope 1 does not contact the power capsule 2, thereby facilitating the patient to swallow the device. Before directly administering the drug to the affected area, the medical staff controls the magnetically controlled capsule gastroscope 1 to move up and down, so that a relative displacement occurs between the magnetically controlled capsule gastroscope 1 and the power capsule 2 and the drug storage capsule 3. The limiting rings 16 and the steering plates 17 in the folding tube 4 cooperate with each other to limit the bending direction and the shape of the folding tube 4 after bending. When the folding tube 4 is bent, the second docking plate 14 on the magnetically controlled capsule gastroscope 1 and the power capsule 2 are The first docking plate 12 on the capsule 2 is always on the same vertical plane, so that the folding tube 4 can only bend toward the position of the first docking plate 12 and the second docking plate 14, so that the magnetically controlled capsule gastroscope 1 and the power capsule 2 finally contact each other. At this time, the first docking plate 12 and the second docking plate 14 remain aligned, and the magnetic metal plate 13 on the power capsule 2 drives the outer shell 15 to be stuck into the docking groove 1401 along the docking guide angle 1402 under the magnetic attraction of the magnet inside the magnetically controlled capsule gastroscope 1, so that the first docking plate 12 and the second docking plate 14 are fitted together, and then the magnetically controlled capsule gastroscope 1 and the power capsule 2 are folded and assembled, so that the direction of the camera device of the magnetically controlled capsule gastroscope 1 is parallel to the direction of the drug administration nozzle 5. At this time, the position and direction of the drug administration nozzle 5 can be accurately controlled by controlling the movement of the magnetically controlled capsule gastroscope 1. While the magnetically controlled capsule gastroscope 1 photographs the affected area, the power component is controlled to push out the medicine in the medicine storage capsule 3 and spray it on the affected area, thereby achieving precise drug administration.

[0051] like Fig.10 As shown, gelatin blocks 18 are fixedly installed at both ends of the folding tube 4, and the two gelatin blocks 18 are respectively fixedly installed on the side walls of the magnetically controlled capsule gastroscope 1 and the power capsule 2 which are close to each other. In the present embodiment, the gelatin blocks 18 are mainly made of food-grade medicinal enteric gelatin, which can be kept in the stomach for a long time without being quickly dissolved; specifically, by arranging the gelatin blocks 18, the two ends of the folding tube 4 are respectively fixed to the magnetically controlled capsule gastroscope 1 and the power capsule 2 through the two gelatin blocks 18. When the examination and medication are completed, the medical staff controls the magnet inside the magnetically controlled capsule gastroscope 1 to weaken the magnetism, so that the magnetically controlled capsule gastroscope 1 and the power capsule 2 are separated under the action of gravity, and then the gelatin blocks 18 at both ends of the folding tube 4 are gradually dissolved under the action of the patient's own digestive system, so that the magnetically controlled capsule gastroscope 1, the folding tube 4 and the medication capsule are separated from each other, so that the device is decomposed into multiple small parts, which is convenient for the patient to discharge the device later.

[0052] like Fig. 9 , Fig.10 As shown, a connecting rope 19 is provided inside the folding tube 4, and the connecting rope 19 is located inside a plurality of limit rings 16. Two ends of the connecting rope 19 respectively pass through the two ends of the folding tube 4 and extend to the inside of two gelatin blocks 18, and one end of the connecting rope 19 located inside the gelatin block 18 is fixedly installed with a clamping block 20; specifically, by providing the connecting rope 19 and the clamping block 20, the clamping blocks 20 at both ends of the connecting rope 19 are respectively located inside the two gelatin blocks 18, and the connecting rope 19 and the clamping block 20 can improve the connection strength between the two ends of the folding tube 4 and the gelatin block 18. When the folding tube 4 is bent, the clamping block 20 located inside the gelatin block 18 can prevent the gelatin block 18 from directly tearing the rubber surface of the folding tube 4.

[0053] like Figure 1 , Figure 2 As shown, the first soft rubber shell 21 is fixedly installed on the side where the magnetically controlled capsule gastroscope 1 and the power capsule 2 are close to each other, and the two ends of the folding tube 4 are respectively fixedly installed inside the two first soft rubber shells 21. In this embodiment, the first soft rubber shell 21 is adhered to the magnetically controlled capsule gastroscope 1, the power capsule 2 and the folding tube 4 by edible glue. Fig.10 As shown, the two gelatin blocks 18 are respectively located inside the two first soft rubber shells 21, and a plurality of first rubber lifting plates 22 are fixedly installed on the side walls of the first soft rubber shells 21; specifically, by setting the first soft rubber shells 21, when the device is taken out of the package, the first rubber lifting plates 22 are first cut, and the first soft rubber shells 21 are torn off from one side of the magnetically controlled capsule gastroscope 1 and the power capsule 2 by using the cut first rubber lifting plates 22, so that the gelatin blocks 18 are exposed to the outside. The first soft rubber shells 21 can wrap the two gelatin blocks 18 inside for protection, so as to prevent the gelatin blocks 18 from getting damp or prematurely debonding from the magnetically controlled capsule gastroscope 1, the power capsule 2 and the folding tube 4.

[0054] like Figure 5 , Figure 6 As shown, a plurality of evenly distributed annular reinforcement frames 23 are fixedly installed on the inner wall of the power capsule 2, and the micro guide rail 7 is fixedly connected to the plurality of annular reinforcement frames 23; specifically, by providing the annular reinforcement frames 23, the plurality of annular reinforcement frames 23 are all fixed on the inner wall of the power capsule 2, which can play a positioning role for the micro guide rail 7, improve the connection strength of the micro guide rail 7 inside the power capsule 2, and enable the micro guide rail 7 to be stably installed on the sealing partition 6, so that the micro guide rail 7 can maintain balance during the movement of the electric slider 8, thereby preventing the micro guide rail 7 from shaking and affecting the introduction of the medicine.

[0055] like Figure 4As shown, a gelatin film 24 is fixedly installed at the bottom of the drug storage capsule 3. In the present embodiment, the gelatin film 24 is mainly made of food-grade medicinal gastric-soluble gelatin, which can be quickly dissolved in the stomach, and the drug delivery nozzle 5 is located inside the gelatin film 24. Specifically, by setting the gelatin film 24, the outside of the drug delivery nozzle 5 is wrapped with a layer of gelatin film 24, which can protect the drug delivery nozzle 5. On the one hand, it can prevent dust and bacteria from entering the drug storage capsule 3 through the drug spraying micropores 501 on the drug delivery nozzle 5 and mixing into the medicine in the process of taking out the device and swallowing by the patient. On the other hand, it can further prevent the medicine in the drug storage capsule 3 from leaking out. After the patient swallows, the gelatin film 24 on the outer surface of the drug delivery nozzle 5 will dissolve within a few minutes after contacting the gastric juice, thereby not hindering the subsequent discharge of the medicine.

[0056] like Figure 3 As shown, a second soft rubber shell 25 is fixedly installed at the bottom of the medicine storage capsule 3, and the gelatin film 24 is located inside the second soft rubber shell 25. In the present embodiment, the second soft rubber shell 25 is adhered to the medicine storage capsule 3 by means of edible glue, and a plurality of second rubber lifting plates 26 are fixedly installed on the side wall of the second soft rubber shell 25; specifically, by providing the second soft rubber shell 25, when the device is taken out of the package, it is necessary to cut the second rubber lifting plates 26 and tear off the second soft rubber shell 25 from the bottom of the medicine storage capsule 3, and the second soft rubber shell 25 can protect the internal gelatin film 24, and prevent the gelatin film 24 from being damaged or being hydrolyzed prematurely outside the patient's body, thereby losing its function.

[0057] A gastroenteroscopic drug delivery method based on the drug delivery device of the present invention comprises the following steps:

[0058] S1. Preparation for medication: The patient wears the image recorder and lies on the bed. The medical staff takes the device out of the package, tears off the first soft rubber cover 21 and the second soft rubber cover 25, and hands the device to the patient to swallow:

[0059] S2. Location of the affected part: The medical staff controls the magnetically controlled capsule gastroscope 1 to move in the patient's stomach through an external magnetic field control device, and observes the patient's stomach in real time through a software imaging workstation and an image recorder worn by the patient until the affected part is found:

[0060] S3. Folding of the device: The medical staff controls the magnetically controlled capsule gastroscope 1 and the power capsule 2 to contact each other, and the magnetic metal plate 13 is inserted into the docking groove 1401. The magnetically controlled capsule gastroscope 1 and the power capsule 2 are folded and assembled so that the direction of the camera device of the magnetically controlled capsule gastroscope 1 is parallel to the direction of the drug delivery nozzle 5:

[0061] S4. Precise drug delivery: The position and direction of the drug delivery nozzle 5 are precisely controlled by controlling the movement of the magnetically controlled capsule gastroscope 1. While the magnetically controlled capsule gastroscope 1 is photographing the affected area, the medicine is squeezed by the power component so that the medicine is sprayed on the affected area under pressure, thereby achieving direct and precise drug delivery:

[0062] S5. Device excretion: After the drug administration is completed, the medical staff controls the magnetically controlled capsule gastroscope 1 to separate from the power capsule 2, and the gelatin block 18 gradually dissolves in the patient's body, so that the magnetically controlled capsule gastroscope 1, the folding tube 4 and the drug administration capsule are separated from each other, and the device is decomposed into multiple small parts, which is convenient for the patient to excrete the device later.

[0063] In summary: before use: the patient first wears the image recorder and lies on the bed, and the medical staff takes the device out of the package, cuts the first rubber sheet 22, and uses the cut first rubber sheet 22 to tear off the first soft rubber shell 21 from one side of the magnetically controlled capsule gastroscope 1 and the power capsule 2, and then cuts the second rubber sheet 26 and tears the second soft rubber shell 25 from the bottom of the drug storage capsule 3, and gives the device to the patient to drink water and swallow into the stomach;

[0064] During use: the medical staff controls the movement of the magnetically controlled capsule gastroscope 1 in the patient's stomach through the external magnetic field control device in cooperation with the controllable magnet inside the magnetically controlled capsule gastroscope 1, and observes the patient's stomach condition in real time through the software imaging workstation and the image recorder worn by the patient until the affected area is found. The medical staff controls the magnetically controlled capsule gastroscope 1 to carry the medication capsule and move close to the affected area. The medical staff controls the magnetically controlled capsule gastroscope 1 to move up and down, so that a relative displacement occurs between the magnetically controlled capsule gastroscope 1 and the power capsule 2 and the drug storage capsule 3. The limiting ring 16 and the steering plate 17 in the folding tube 4 cooperate with each other to limit the bending direction and the shape of the folding tube 4 after bending. When the folding tube 4 is bent, the second docking plate 14 on the magnetically controlled capsule gastroscope 1 and the first docking plate 12 on the power capsule 2 are always on the same vertical plane, so that the folding tube 4 can only bend toward the position of the first docking plate 12 and the second docking plate 14, so that the magnetically controlled capsule gastroscope 1 and the power capsule 2 finally contact each other. At this time, the first docking plate 12 and the second docking plate 14 are in contact with each other. The two docking plates 14 remain aligned, and the magnetic metal plate 13 on the power capsule 2 drives the outer shell 15 to be stuck into the docking groove 1401 along the docking guide angle 1402 under the magnetic attraction of the magnet inside the magnetically controlled capsule gastroscope 1, so that the first docking plate 12 and the second docking plate 14 are fitted together, and then the magnetically controlled capsule gastroscope 1 and the power capsule 2 are folded and assembled, so that the direction of the camera device of the magnetically controlled capsule gastroscope 1 is parallel to the direction of the drug administration nozzle 5. At this time, the position and direction of the drug administration nozzle 5 can be accurately controlled by controlling the movement of the magnetically controlled capsule gastroscope 1. While the magnetically controlled capsule gastroscope 1 photographs the affected part, the electric slider 8 inside the power capsule 2 is controlled to start sliding along the micro guide rail 7, so that the power frame 10 is driven to slide in the sealing slide hole 601 through the traveling frame 9, so that the medicine pushing plate 11 at one end of the power frame 10 squeezes the medicine in the medicine storage capsule 3, so that the medicine is directly ejected from each medicine spraying microhole 501 under the action of pressure, and then the medicine liquid is sprayed on the affected part, realizing direct and precise drug administration;

[0065] After use: After the examination and medication are completed, the medical staff controls the magnet inside the magnetically controlled capsule gastroscope 1 to weaken the magnetism, so that the magnetically controlled capsule gastroscope 1 and the power capsule 2 are separated under the action of gravity, and then the gelatin blocks 18 at both ends of the folding tube 4 are gradually dissolved under the action of the patient's own digestive system, so that the magnetically controlled capsule gastroscope 1, the folding tube 4 and the medication capsule are separated from each other, and the device is decomposed into multiple small parts, which is convenient for the patient to excrete the device later.

[0066] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The above embodiments and descriptions only describe the principles of the present invention. The present invention may be subject to various changes and improvements without departing from the spirit and scope of the present invention. These changes and improvements fall within the scope of the present invention. The scope of protection claimed by the present invention is defined by the attached claims and their equivalents.

Claims

1. A convenient gastroscopic drug delivery device and method, characterized in that: It comprises a magnetically controlled capsule gastroscope (1) and a drug-delivery capsule, wherein the drug-delivery capsule is used to directly deliver drug to the patient's stomach in coordination with the movement of the magnetically controlled capsule gastroscope (1); The drug delivery capsule comprises a power capsule (2), a drug storage capsule (3) is fixedly installed on a side of the power capsule (2) away from the magnetically controlled capsule gastroscope (1), and the drug storage capsule (3) is used to store drugs. A folding tube (4) is arranged between the magnetically controlled capsule gastroscope (1) and the power capsule (2), a drug delivery nozzle (5) is fixedly installed at the bottom of the drug storage capsule (3), and a plurality of evenly distributed drug spraying micropores (501) are opened on the drug delivery nozzle (5), and the drug spraying micropores (501) are all connected to the interior of the drug storage capsule (3), and a sealing partition (6) is fixedly installed inside the drug storage capsule (3), and the sealing partition (6) is located at the junction of the power capsule (2) and the drug storage capsule (3), and a power component is arranged inside the power capsule (2); The power assembly is used to squeeze the medicine in the medicine storage capsule (3) so that the medicine is sprayed to the outside from the medicine spraying micropores (501) on the drug delivery nozzle (5). The power assembly includes a micro guide rail (7) arranged inside the power capsule (2). The micro guide rail (7) is fixedly installed on the top of the sealing partition (6). An electric slider (8) is driven and installed on one side of the micro guide rail (7). A traveling frame (9) is fixedly installed on the side wall of the electric slider (8). A power frame (10) is fixedly installed on one end of the traveling frame (9). A sealing sliding hole (601) is opened on the top of the sealing partition (6). The bottom end of the power frame (10) passes through the sealing sliding hole (601) and extends to the inside of the folding tube (4) and is fixedly installed with a medicine pushing plate (11). A first docking plate (12) is fixedly mounted on both sides of the medicine storage capsule (3), a magnetic metal plate (13) is fixedly mounted on the side wall of the first docking plate (12), an outer shell (15) is fixedly mounted on the side wall of the first docking plate (12), and the two magnetic metal plates (13) are respectively located inside the two outer shells (15). A second docking plate (14) is fixedly mounted on both sides of the magnetically controlled capsule gastroscope (1), and the positions of the two first docking plates (12) correspond to the positions of the two second docking plates (14) respectively. A docking groove (1401) adapted to the outer shell (15) is provided on the side wall of the second docking plate (14), and a docking chamfer (1402) is provided on the side edge of the docking groove (1401). A plurality of uniformly distributed limiting rings (16) are fixedly mounted inside the folding tube (4), and a plurality of mutually hinged steering plates (17) are fixedly mounted between any two adjacent limiting rings (16).

2. A convenient gastroscopic drug delivery device and method according to claim 1, characterized in that: Gelatin blocks (18) are fixedly mounted on both ends of the folding tube (4), and the two gelatin blocks (18) are respectively fixedly mounted on the side walls of the magnetically controlled capsule gastroscope (1) and the power capsule (2) that are close to each other.

3. A convenient gastroscopic drug delivery device and method according to claim 2, characterized in that: A connecting rope (19) is provided inside the folding tube (4), and the connecting rope (19) is located inside the plurality of limiting rings (16). Two ends of the connecting rope (19) respectively pass through the two ends of the folding tube (4) and extend to the inside of the two gelatin blocks (18). A clamping block (20) is fixedly installed on one end of the connecting rope (19) located inside the gelatin block (18).

4. A convenient gastroscopic drug delivery device and method according to claim 2, characterized in that: A first soft rubber shell (21) is fixedly installed on the side where the magnetically controlled capsule gastroscope (1) and the power capsule (2) are close to each other, and the two ends of the folding tube (4) are respectively fixedly installed inside the two first soft rubber shells (21), and the two gelatin blocks (18) are respectively located inside the two first soft rubber shells (21), and a plurality of first rubber lifting plates (22) are fixedly installed on the side walls of the first soft rubber shells (21).

5. The convenient-to-use gastroscopic drug delivery device and method according to claim 1, characterized in that: A plurality of evenly distributed annular reinforcement frames (23) are fixedly mounted on the inner wall of the power capsule (2), and the micro guide rail (7) is fixedly connected to the plurality of annular reinforcement frames (23).

6. A convenient gastroscopic drug delivery device and method according to claim 1, characterized in that: A gelatin film (24) is fixedly mounted on the bottom of the drug storage capsule (3), and the drug delivery nozzle (5) is located inside the gelatin film (24).

7. A convenient gastroscopic drug delivery device and method according to claim 6, characterized in that: A second soft rubber shell (25) is fixedly mounted on the bottom of the medicine storage capsule (3), the gelatin film (24) is located inside the second soft rubber shell (25), and a plurality of second rubber lifting plates (26) are fixedly mounted on the side wall of the second soft rubber shell (25).

8. A gastroenteroscopic drug delivery method based on the drug delivery device according to claims 1 to 7, characterized in that: The following steps are involved: S1. Preparation for medication: The patient wears the image recorder and lies on the bed. The medical staff takes the device out of the package, tears off the first soft rubber cover (21) and the second soft rubber cover (25), and hands the device to the patient to swallow: S2. Location of the affected part: The medical staff controls the magnetically controlled capsule gastroscope (1) to move in the patient's stomach through an external magnetic field control device, and observes the patient's stomach in real time through a software imaging workstation and an image recorder worn by the patient until the affected part is found: S3. Folding of the device: The medical staff controls the magnetically controlled capsule gastroscope (1) and the power capsule (2) to contact each other, and the magnetic metal plate (13) is inserted into the docking groove (1401). The magnetically controlled capsule gastroscope (1) and the power capsule (2) are folded and assembled so that the direction of the imaging device of the magnetically controlled capsule gastroscope (1) is parallel to the direction of the drug delivery nozzle (5). S4. Precise drug delivery: The position and direction of the drug delivery nozzle (5) are precisely controlled by controlling the movement of the magnetically controlled capsule gastroscope (1). While the magnetically controlled capsule gastroscope (1) is photographing the affected area, the drug is squeezed by the power component so that the drug is sprayed on the affected area under pressure, thereby achieving direct and precise drug delivery: S5. Device excretion: After the drug administration is completed, the medical staff controls the magnetically controlled capsule gastroscope (1) to separate from the power capsule (2), and the gelatin block (18) gradually dissolves in the patient's body, so that the magnetically controlled capsule gastroscope (1), the folding tube (4) and the drug administration capsule are separated from each other, and the device is decomposed into multiple small parts, which is convenient for the patient to excrete the device later.

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