Novel cattle liver biopsy sampler

By designing a combined structure of bovine liver biopsy sampler, the problem of difficulty in cleaning and adjusting the depth of the needle core in the prior art is solved, and the effect of efficient cleaning, reducing the risk of cross infection and improving sampling accuracy is achieved.

CN119405356APending Publication Date: 2025-02-11HENAN AGRICULTURAL UNIVERSITY
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Patent Information

Application Number
CN202411535669.0
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-10-31
Publication Date
2025-02-11

AI Technical Summary

Technical Problem

The existing bovine liver biopsy sampler has an integrated structure in the needle core design, which makes it difficult to thoroughly clean and disinfect, increases the risk of cross-infection, and cannot adjust the interlacing depth, affecting the sampling results and surgical safety.

Method used

A new type of bovine liver biopsy sampler was designed, adopting a combined structure of puncture needle cannula, trocar assembly and negative pressure sampling assembly. The puncture needle cannula is a hollow structure, and the trocar assembly includes a moving screw and a needle core. The core can be easily disassembled and cleaned by threaded connection, and isosceles trapezoidal chute and positioning card block are provided on the inner wall of the puncture needle casing to achieve stable fixation and depth adjustment of the needle core.

Benefits of technology

It realizes efficient cleaning and disinfection of the sampler, reduces the risk of cross-infection, improves the accuracy and safety of sampling results, and enhances operation flexibility and reduces surgical risks.

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Abstract

The invention discloses a novel cattle liver biopsy sampler, which belongs to the technical field of medical apparatus and instruments, and comprises a puncture needle cannula, a trocar assembly and a negative pressure sampling assembly, the trocar assembly is used for assisting the puncture needle cannula to be inserted into the cattle liver and smoothly withdrawn after insertion is completed; the negative pressure sampling assembly is connected with the puncture needle cannula after the trocar assembly is withdrawn and is used for sampling the target tissue; the puncture needle sleeve is of a hollow structure, and an isosceles trapezoid-shaped sliding groove is formed in the inner wall of the puncture needle sleeve. And threads matched with the positioning sleeve are arranged on the outer side wall of the puncture needle sleeve. The needle core can be controlled to be inserted or withdrawn according to needs, the operation flexibility is improved, the operation difficulty is reduced, and the success rate of an operation is increased.
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Description

Technical Field

[0001] The invention belongs to the technical field of medical instruments, and in particular relates to a novel bovine liver biopsy sampler. Background Art

[0002] Liver puncture biopsy of cattle is a commonly used technique in veterinary clinics and scientific research. It is a technique that obtains a small amount of liver tissue samples by puncturing the liver and performs pathological examination to clarify the nature of liver lesions. It is mainly used for the diagnosis and differential diagnosis of liver diseases and the evaluation of drug exposure in the liver. At present, when performing liver puncture on ruminants such as cattle, the animals are anesthetized and restrained in a supine position. The hair on the chest and upper abdomen is shaved and the epidermis is disinfected. The skin, muscle and peritoneum are pierced with a cannula needle. The puncture syringe is inserted and a small amount of physiological saline is injected into the abdominal cavity. A small amount of liquid is retained in the syringe and back-drawn to form a negative pressure. When the animal exhales, the liver is quickly punctured and extracted. The liver tissue enters the syringe, and the needle is immediately pulled out. The puncture site is pressed for a few seconds with gauze or sponge to stop bleeding.

[0003] However, the existing design still has some shortcomings in the needle core structure and function. At present, the biopsy sampler for cattle liver is mainly composed of a puncture needle sleeve and a needle core running through it. However, in the design of the needle core, most of them adopt an integrated structure. The needle core of the integrated structure makes it difficult to thoroughly clean and disinfect the entire sampler after use. Since cattle liver tissue may contain various biological components and residues, if the sampler cannot be fully cleaned, the risk of cross infection will increase, affecting the safety and effectiveness of subsequent use. Difficult cleaning may also cause dirt and bacteria to accumulate inside the sampler, which will have an adverse effect on the performance and life of the sampler under long-term use. The needle core of the integrated structure limits its flexibility during the sampling process. In addition, in actual operation, according to the different parts and pathological conditions of the cattle liver, it may be necessary to adjust the insertion depth of the needle core to obtain more accurate sampling results; however, the integrated structure sampler often cannot meet this demand, resulting in a certain impact on the sampling results. The inability to adjust the insertion depth may also increase the risk of surgery, because too deep or too shallow puncture may cause unnecessary damage to the cattle liver. Summary of the invention

[0004] In view of the shortcomings of the prior art, the present invention discloses a novel bovine liver biopsy sampler, which is a living minimally invasive liver sampler designed to minimize harm to animals, reduce the risks of bleeding and infection, and ensure that high-quality, fresh liver tissue samples can be obtained for subsequent scientific research or clinical diagnosis.

[0005] To achieve the above object, the present invention provides the following technical solutions:

[0006] The present invention provides a novel bovine liver biopsy sampler, which comprises a puncture needle cannula, a cannula needle assembly and a negative pressure sampling assembly; the cannula needle assembly is used to assist the puncture needle cannula in inserting into the bovine liver and to withdraw smoothly after the insertion is completed; the negative pressure sampling assembly is connected to the puncture needle cannula after the cannula needle assembly withdraws to sample the target tissue; the puncture needle cannula is a hollow structure, and a first handle is fixedly installed on the top of the cannula needle assembly, and isosceles trapezoidal grooves are symmetrically opened on the inner wall of the puncture needle cannula; a thread matching the positioning sleeve is provided on the outer wall of the puncture needle cannula; one end of the first converter is connected to the puncture needle cannula, and the other end is connected to one end of the silicone tube; the other end of the silicone tube is connected to one end of the second converter, and the other end of the second converter is connected to the main channel of the three-way pipe; one branch channel of the three-way pipe is connected to the negative pressure device, and the other branch channel is used as a reserved interface for connecting the cleaning assembly.

[0007] Furthermore, the positioning sleeve is made of silicone and has a certain curvature, which ensures that the puncture needle cannula fits the target surface more firmly during use.

[0008] Furthermore, the trocar assembly includes a movable screw and a needle core, wherein the needle core is fixedly mounted on the end of the movable screw; a second handle is fixedly mounted on the top of the movable screw, and the second handle matches the first handle.

[0009] Furthermore, the outer surface of the movable screw is cylindrical and matches the puncture needle sleeve, and the movable screw can also slide smoothly inside the puncture needle sleeve.

[0010] Furthermore, two positioning blocks are symmetrically arranged on the outer surface of the moving screw, and the positioning blocks are made of nylon elastomer and are in an isosceles inverted trapezoidal structure. The positioning blocks are made of nylon elastomer, which has excellent tensile strength and wear resistance.

[0011] Furthermore, the positioning block penetrates the outer surface of the moving screw and matches the slideway, and a retractable spring is provided between the two positioning blocks; the bottom angles of the slideway and the positioning block are the same, and are both 15° to 30°. The bottom angles of the slideway and the positioning block are the same, and both are isosceles trapezoidal structures, so their top angles are also the same, and a retractable spring is provided between the symmetrical positioning blocks, so that the two fit more closely when in contact, thereby playing a role of positioning and fixing.

[0012] Furthermore, the end of the movable screw is a threaded sleeve; one end of the needle core is a needle head and the other end is a threaded rod, and the threaded rod matches the threaded sleeve. When in use, the threaded rod end of the needle core is tightly connected to the threaded sleeve of the movable screw by rotation, and it is easy to disassemble and clean.

[0013] Furthermore, the outer surfaces of the puncture needle sleeve, the movable screw and the needle core are all provided with scale lines. The insertion depth of the needle core can be adjusted according to actual needs. This will help improve the accuracy and safety of sampling and reduce surgical risks.

[0014] Compared with the prior art, the present invention has the following beneficial effects:

[0015] (1) The present invention provides a novel bovine liver biopsy sampler. When in use, the needle core needs to be threadedly fixedly connected with the threaded sleeve at the end of the moving screw rod to form a stable cannula needle assembly. Subsequently, the cannula needle assembly is inserted into the interior of the puncture needle cannula from the top port thereof. Under the action of external force, the needle head can smoothly penetrate the puncture needle cannula until its end, reaching a predetermined sampling position. In addition, an isosceles trapezoidal slide groove is provided on the inner wall of the puncture needle cannula, and a positioning block matching the same is designed on the moving screw rod to achieve limited fixation, thereby firmly fixing the needle core; the slide groove and the positioning block are both in the shape of an isosceles trapezoid, and a telescopic spring is also provided between the two positioning blocks. This design not only enhances the stability of the structure, but also enables the moving screw rod to smoothly advance or retreat, thereby facilitating the control of the insertion or withdrawal of the needle core as needed, thereby improving the flexibility of operation, reducing the difficulty of operation, and improving the success rate of the operation.

[0016] (2) The present invention designs the movable screw and the needle core that penetrate the puncture needle cannula as a detachable structure, which is convenient for subsequent cleaning and disinfection and improves the flexibility and maintainability of the sampler; at the same time, scales are provided on the puncture needle cannula, the needle core, and the movable screw, and adjustment and positioning components are also provided on the puncture needle cannula and the movable screw, allowing 1 and fixation, which helps to improve the accuracy and safety of sampling and reduce surgical risks. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the overall structure of the trocar assembly of the present invention located in the puncture needle cannula;

[0018] Figure 2 This is a schematic diagram of the overall structure of the negative pressure sampling assembly of the present invention connected to the puncture needle cannula for sampling;

[0019] Figure 3 It is a schematic structural diagram of the trocar assembly of the present invention;

[0020] Figure 4 For the present invention Figure 1 A partial enlarged picture of part A in the middle.

[0021] In the figure: 1 puncture needle cannula, 2 first handle, 3 slide groove, 4 movable screw, 5 positioning block, 6 threaded sleeve, 7 second handle, 8 needle core, 9 threaded sleeve, 10 positioning sleeve, 11 telescopic spring, 12 first converter, 13 silicone tube, 14 second converter, 15 three-way tube, 16 negative pressure device. DETAILED DESCRIPTION

[0022] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0023] In the description of the present invention, it should be noted that the directions or positional relationships indicated by the terms "upper", "lower", "left", "right", "inner", "outer", etc. are based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as limiting the present invention; in addition, the terms "first" and "second" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance.

[0024] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0025] The present invention provides a novel bovine liver biopsy sampler. The technical solution of the present invention is further described below in conjunction with the accompanying drawings:

[0026] See also Figure 1 and Figure 2It can be seen that the present invention provides a novel bovine liver biopsy sampler, which includes a puncture needle cannula 1, a cannula needle assembly and a negative pressure sampling assembly; the cannula needle assembly is used to assist the puncture needle cannula 1 in inserting into the bovine liver and to withdraw smoothly after the insertion is completed; the negative pressure sampling assembly is connected to the puncture needle cannula 1 after the cannula needle assembly withdraws to sample the target tissue; the puncture needle cannula 1 is a hollow structure, and a first handle 2 is fixedly installed on its top, and isosceles trapezoidal grooves 3 are symmetrically opened on the inner wall of the puncture needle cannula 1; a thread matching the positioning sleeve 10 is provided on the outer wall of the puncture needle cannula 1; one end of the first converter 12 is connected to the puncture needle cannula 1, and the other end is connected to one end of the silicone tube 13; the other end of the silicone tube 13 is connected to one end of the second converter 14, and the other end of the second converter 14 is connected to the main channel of the three-way pipe 15; one branch channel of the three-way pipe 15 is connected to the negative pressure device 16, and the other branch channel is used as a reserved interface for connecting the cleaning assembly. The connection between the first converter 12, the puncture needle cannula 1, the silicone tube 13, the second converter 14, and the three-way tube 15 can be fixed with a clip to ensure that the connection is stable and firm. When the tip of the puncture needle cannula 1 penetrates the cow's skin and enters the cow's liver substance, and the cannula needle assembly is withdrawn, one end of the silicone tube 13 is connected to the top port of the puncture needle cannula 1 through the first converter 12, and the other end of the silicone tube 13 is connected to the three-way tube 15 through the second converter 14. A branch channel of the three-way tube 15 is connected to the negative pressure device. When the tip of the puncture needle cannula cuts the liver, negative pressure suction is performed to avoid the problem that the liver tissue is easily detached in the abdominal cavity after being cut, resulting in sampling failure.

[0027] In the above embodiment, the positioning sleeve 10 is made of silicone and has a certain curvature, which ensures that the puncture needle cannula 1 fits the target surface more firmly during use.

[0028] See also Figure 1 and Figure 3 It can be seen that in the above embodiment, the trocar assembly includes a movable screw 4 and a needle core 8, and the needle core 8 is fixedly installed at the end of the movable screw 4; the outer surface of the movable screw 4 is cylindrical and matches the puncture needle sleeve (1), and the movable screw (4) can also slide smoothly inside the puncture needle sleeve 1; a second handle 7 is fixedly installed at the top of the movable screw 4, and the second handle 7 matches the first handle 2.

[0029] See also Figure 1 , Figure 3 and Figure 4It can be seen that in the above embodiment, two positioning blocks 5 are symmetrically arranged on the outer surface of the moving screw 4, and the material of the positioning blocks 5 is nylon elastomer and its shape is an isosceles inverted trapezoidal structure. The positioning blocks 5 penetrate the outer surface of the moving screw 4 and match the slide slot 3, and a retractable spring 11 is arranged between the two positioning blocks 5; the bottom angles of the slide slot 3 and the positioning blocks 5 are the same, and both are 15° to 30°. It is worth noting that the bottom angles of the slide slot 3 and the positioning blocks 5 are the same, and both are in the shape of an isosceles trapezoidal structure, so the top angles of the two are also the same, and a retractable spring 11 is arranged between the symmetrical positioning blocks 5, so that the two fit more closely when in contact, thereby playing a role of positioning and fixing. Specifically, when the movable screw 4 moves along the puncture needle sleeve 1 under the action of external force, since a retractable spring is connected between the positioning block 5 located on the movable screw 4, the positioning block 5 moves closely against the inner wall of the puncture needle sleeve 1. When it moves to the position of the slide groove 3, the positioning block 5 is smoothly inserted into the slide groove 3 under the action of the spring 11, thereby achieving temporary fixed limit of the movable screw 4 and the needle core 8. On this basis, by applying a certain external force to the second handle 7, the positioning block 5 on the movable screw 4 can be disengaged from the slide groove 3, so that the movable screw 4 and the needle core 8 can move again in the puncture needle sleeve 1.

[0030] In the above embodiment, the end of the movable screw rod 4 is a threaded sleeve 6 ; one end of the needle core 8 is a needle head and the other end is a threaded rod 9 , and the threaded rod 9 matches the threaded sleeve 6 .

[0031] In the above embodiment, scale lines are provided on the outer surfaces of the puncture needle sleeve 1, the movable screw rod 4 and the needle core 8, so that the operator can adjust the insertion depth of the needle core 8 according to actual needs.

[0032] Working principle: When implementing the operation, firstly, the needle core 8 needs to be threadedly fixedly connected with the threaded sleeve 6 at the end of the movable screw 4 to form a stable trocar needle assembly; then, the trocar needle assembly is inserted from the top port of the puncture needle sleeve and is ready for use. Select the puncture point, and then shave, clean, disinfect, and perform local anesthesia on the puncture point of the cattle to be sampled; use a No. 23 blade to make an incision of about 0.5 cm in the skin, and pierce the cow's skin with the tip of the end of the puncture needle sleeve 1 containing the trocar needle assembly assembled above into the cow's liver substance. After reaching the predetermined sampling position, the puncture needle sleeve 1 is limited and fixed by the positioning sleeve 10, and then the trocar needle assembly is withdrawn from the puncture needle sleeve, and then the negative pressure sampling assembly, that is, one end of the silicone tube 13 is passed through The first converter 12 is connected to the top port of the puncture needle cannula 1, and the other end of the silicone tube 13 is connected to the three-way tube 15 through the second converter 14. A branch channel of the three-way tube 15 is connected to the negative pressure device. When the tip of the end of the puncture needle cannula cuts the liver, negative pressure suction is performed, and the sucked bovine liver tissue sample is stored in the negative pressure device sample storage tube. After the sampling is completed, the puncture needle cannula 1 is slowly withdrawn, and the sucked liver tissue sample is pressed out of the negative pressure device sample storage tube and stored in the sample bottle for use. Another branch channel of the three-way tube 15 is connected to the cleaning component, and physiological saline is used to clean the silicone tube, the converter and the puncture needle cannula. The cannula needle component can also be disassembled for cleaning and disinfection.

[0033] The above is a detailed introduction to a novel bovine liver biopsy sampler disclosed in the present invention. This article uses specific examples to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only used to help understand the method of the present invention and its core idea. It should be pointed out that for ordinary technicians in this technical field, without departing from the principle of the present invention, the present invention can also be improved and modified, and these improvements and modifications also fall within the scope of protection of the claims of the present invention.

Claims

1. A novel bovine liver biopsy sampler, characterized in that: The biopsy device comprises a puncture needle cannula (1), a cannula needle assembly and a negative pressure sampling assembly; the cannula needle assembly is used to assist the puncture needle cannula (1) in inserting into the bovine liver and to be smoothly withdrawn after the insertion is completed; the negative pressure sampling assembly is connected to the puncture needle cannula (1) after the cannula needle assembly is withdrawn to sample the target tissue; the puncture needle cannula (1) is a hollow structure, and a first handle (2) is fixedly installed on the top of the puncture needle cannula (1); an isosceles trapezoidal sliding groove (3) is symmetrically provided on the inner wall of the puncture needle cannula (1); the puncture needle cannula (1) ) is provided with a thread matching the positioning sleeve (10) on its outer wall; one end of the first converter (12) is connected to the puncture needle sleeve (1), and the other end is connected to one end of the silicone tube (13); the other end of the silicone tube (13) is connected to one end of the second converter (14), and the other end of the second converter (14) is connected to the main channel of the three-way tube (15); one branch channel of the three-way tube (15) is connected to the negative pressure device (16), and the other branch channel serves as a reserved interface for connecting the cleaning component.

2. A novel bovine liver biopsy sampler according to claim 1, characterized in that: The positioning sleeve (10) is made of silicone and has a certain curvature, thereby ensuring that the puncture needle cannula (1) fits the target surface more firmly during use.

3. A novel bovine liver biopsy sampler according to claim 1, characterized in that: The trocar assembly comprises a movable screw (4) and a needle core (8), wherein the needle core (8) is fixedly mounted at the end of the movable screw (4); a second handle (7) is fixedly mounted at the top of the movable screw (4), and the second handle (7) matches the first handle (2).

4. A novel bovine liver biopsy sampler according to claim 3, characterized in that: The outer surface of the movable screw (4) is cylindrical and matches the puncture needle sleeve (1), and the movable screw (4) can also slide smoothly inside the puncture needle sleeve (1).

5. A novel bovine liver biopsy sampler according to claim 4, characterized in that: Two positioning blocks (5) are symmetrically arranged on the outer surface of the movable screw rod (4); the positioning blocks (5) are made of nylon elastomer and are in the shape of an isosceles inverted trapezoidal structure.

6. A novel bovine liver biopsy sampler according to claim 5, characterized in that: The positioning block (5) penetrates the outer surface of the movable screw rod (4) and matches the slide groove (3), and a retractable spring (11) is provided between the two positioning blocks (5).

7. A novel bovine liver biopsy sampler according to claim 6, characterized in that: The bottom angles of the slide groove (3) and the positioning block (5) are the same, and are both 15° to 30°.

8. A novel bovine liver biopsy sampler according to claim 3, characterized in that: The end of the movable screw rod (4) is a threaded sleeve (6); one end of the needle core (8) is a needle head and the other end is a threaded rod (9), and the threaded rod (9) matches the threaded sleeve (6).

9. A novel bovine liver biopsy sampler according to claim 1, characterized in that: The outer surfaces of the puncture needle sleeve (1), the movable screw rod (4) and the needle core (8) are all provided with scale lines.