Diet composition with low glycemic index as well as preparation method and application thereof

Abstract

The invention provides a diet composition with a low glycemic index as well as a preparation method and application of the diet composition. The diet composition disclosed by the invention can generate a relatively low glycemic index, is anti-inflammatory, is rich in essential amino acids, vitamins and minerals, is beneficial to intake and absorption of nutrients, and can reduce aggressive behaviors of autistic disorder model mice; experiments prove that the method is feasible, different model animals are used for testing, it is found that different model mice have significant differences from mice in a blank control group in the aspect of aggressive behaviors after eating the LGID, the experimental analysis result is reliable, and the system error is small; the diet composition with the low glycemic index fully considers the comprehensiveness of nutritional ingredients and the palatability of food based on the problem that most children with autistic disorders pick food, not only can meet the supplement of different nutrient substances, but also can improve / relieve the occurrence of aggressive behaviors; and service is provided for improving the living quality of autistic disorder patients and improving the good social environment.

Description

Technical Field

[0001] The present invention relates to the field of biomedical technology, and in particular to a low glycemic index dietary composition, a preparation method and an application thereof. Background Art

[0002] Autism is a developmental disorder. The prevalence of autism is increasing year by year. The prevalence in children under 12 years old in my country is about 0.7%. Among them, aggressive behavior is a common problem behavior in children with autism, which affects the development of their attention, learning ability, and social skills. About more than 50% of children with ASD (autism spectrum disorder, i.e. autism) will show aggressive behaviors for no reason, such as hitting and biting. Compared with other children with intellectual disabilities, neurodevelopmental disorders or typical development, ASD children show more direct physical aggression and reactive aggression. In ASD children, aggressive behavior has more serious negative consequences, such as decreased quality of life or reduced educational and social support.

[0003] Studies have found that the phenotype of autism is closely related to diet. A proper diet can help patients reduce the severity of the disease and improve psychological and gastrointestinal symptoms. The glycemic index (GI) refers to the degree of change in blood sugar 2 hours after the body ingests different types of foods containing equal amounts of carbohydrates. It is an important indicator reflecting the rate of food digestion and absorption and blood sugar response. Foods with a GI of less than 55 are usually called low glycemic index foods. Currently, GI has been recognized by the WHO and the Food and Agriculture Organization of the United Nations. The low glycemic index diet (LGID) has been used in the treatment of diseases such as refractory epilepsy, autism in children, and type 2 diabetes. Therefore, in recent years, the world has focused on developing dietary therapies that can alleviate various diseases.

[0004] The prior art discloses a ketogenic diet composition and its preparation method and application, which are mainly used to improve the core symptoms of autistic disorder; the prior art also discloses a ketogenic diet formula and its application in the preparation of preparations for tumor metabolic therapy and radiotherapy sensitization, mainly providing a new method for tumor treatment from the perspectives of metabolic therapy and radiotherapy sensitization; the prior art also discloses a ketogenic diet feed for mice and its preparation method, which are suitable for improving the "three more and one less" symptoms of diabetic mice: the prior art discloses an edible composition, a low glycemic index nutritional powder and its preparation method; the prior art also discloses a low glycemic index brown rice oatmeal bread and its preparation method.

[0005] The above technologies all focus on improving the core symptoms of autism, tumor treatment, diabetes, epilepsy, etc. Diets dedicated to alleviating aggressive behaviors in autism are very rare. Therefore, this field still needs to continue to develop and apply diets that can alleviate and improve aggressive behaviors in autism. Summary of the invention

[0006] The present invention provides a low glycemic index dietary composition and a preparation method and application thereof, so as to solve the defects existing in the prior art.

[0007] In a first aspect, the present invention provides a low glycemic index dietary composition, comprising the following components: protein, starch, cellulose, fish oil, linseed oil, medium-chain fatty acid oil, cocoa butter, minerals, dicalcium phosphate, calcium carbonate, potassium citrate, and vitamins; wherein the starch comprises straight-chain starch and amylopectin.

[0008] Preferably, the low glycemic index dietary composition further comprises: choline bitartrate, L-lysine, L-leucine, L-cystine, L-arabinose, D-ribose, and D-mannose.

[0009] Preferably, the protein in the low glycemic index dietary composition is whey protein.

[0010] Preferably, the medium-chain fatty acid oil in the low glycemic index dietary composition is medium-chain triglyceride oil.

[0011] Preferably, the protein in the low glycemic index dietary composition is whey protein.

[0012] Preferably, the medium-chain fatty acid oil in the low glycemic index dietary composition is medium-chain triglyceride oil.

[0013] Preferably, the low glycemic index dietary composition comprises the following components by mass fraction: 24-26% protein, 20-23% starch, 5-7% cellulose, 1-1.6% fish oil, 0.5-1% linseed oil, 1-2% medium-chain fatty acid oil, 30-33% cocoa butter, 3-3.5% D-mannose, 1-1.5% minerals, 1.5-2% dicalcium phosphate, 0.5-1% calcium carbonate, 2-2.5% potassium citrate, 0.1-0.2% vitamins, 0.2-0.4% choline bitartrate, 0.3-0.5% L-lysine, 0.3-0.6% L-leucine, 0.1-0.3% L-cystine, 1-2% L-arabinose, and 0.4-0.65% D-ribose.

[0014] Preferably, the vitamin in the low glycemic index dietary composition is vitamin C; and the carbon atom in the carbon chain of the medium-chain triglyceride oil is 8.

[0015] Preferably, the starch in the low glycemic index dietary composition comprises amylose and amylopectin, wherein the mass ratio of amylose to amylopectin is (60-80):(20-40).

[0016] In a second aspect, the present invention also provides a method for preparing the low glycemic index dietary composition, comprising the following steps:

[0017] After mixing the raw materials in the low glycemic index diet composition in proportion, adding water, stirring, granulating, and drying;

[0018] The granules are irradiated with gamma rays to obtain a low glycemic index dietary composition.

[0019] In a third aspect, the present invention also provides a use of the low glycemic index dietary composition or the low glycemic index dietary composition prepared by the preparation method in the preparation of a drug for improving aggressive behavior in autistic disorder.

[0020] The present invention has the following beneficial effects compared with the prior art:

[0021] The low glycemic index dietary composition of the present invention comprises protein, starch, cellulose, fish oil, linseed oil, medium-chain fatty acid oil, cocoa butter, minerals, dicalcium phosphate, calcium carbonate, potassium citrate and vitamins; wherein starch comprises amylose and amylopectin; the dietary composition of the present invention can generate a lower glycemic index and is anti-inflammatory, and the essential amino acids, vitamins and minerals rich in the dietary composition are helpful for the intake and absorption of nutrients, and most importantly, can improve the aggressive behavior of autistic disorder model mice; the present invention has been proved to be feasible through experiments, and different model animals have been used for testing, and it is found that the aggressive behavior of different model mice after eating LGID is significantly different from that of blank control group mice, the experimental analysis results are reliable, the system error is small, and the experimental efficiency is high; the low glycemic index dietary composition of the present invention, based on the problem of picky eating of most children with autism, fully considers the comprehensiveness of nutrients and the palatability of food, can not only meet the supplementation of different nutrients, but also improve / mitigate the occurrence of aggressive behavior, and provide services for improving the quality of life of patients with autism and a good social environment. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the prior art descriptions. Obviously, the drawings described below are only some embodiments of the present invention, and for ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0023] Figure 1 The effects of normal diet and LGID diet on blood glucose of mice after fasting for 16 hours;

[0024] Figure 2 The effects of normal diet and LGID diet on the body weight of mice;

[0025] Figure 3 The effect of normal diet and LGID diet on the total number of aggressive behaviors of mice;

[0026] Figure 4 This is the effect of normal diet and LGID diet on the percentage of aggressive behavior in mice. DETAILED DESCRIPTION

[0027] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0028] The following are described in detail. It should be noted that the order of description of the following embodiments is not intended to limit the preferred order of the embodiments. In addition, in the description of the present application, the term "including" means "including but not limited to". Various embodiments of the present invention may exist in the form of a range; it should be understood that the description in the form of a range is only for convenience and simplicity, and should not be understood as a rigid limitation on the scope of the present invention; therefore, it should be considered that the range description has specifically disclosed all possible sub-ranges and single values ​​within the range. For example, it should be considered that the range description from 1 to 6 has specifically disclosed sub-ranges, such as from 1 to 3, from 1 to 4, from 1 to 5, from 2 to 4, from 2 to 6, from 3 to 6, etc., as well as single numbers within the numbered ranges, such as 1, 2, 3, 4, 5 and 6, which apply regardless of the range. In addition, whenever a numerical range is indicated in this article, it is meant to include any quoted numbers (fractions or integers) within the indicated range.

[0029] The invention provides a low glycemic index dietary composition, comprising the following components: protein, starch, cellulose, fish oil, linseed oil, medium-chain fatty acid oil, cocoa butter, minerals, dicalcium phosphate, calcium carbonate, potassium citrate, and vitamins; wherein the starch comprises straight-chain starch and amylopectin.

[0030] The low glycemic index dietary composition of the present invention comprises starch, wherein the starch comprises amylose and amylopectin; wherein amylopectin (amylopectin), also known as gelatin starch, has a relatively large molecule and is generally composed of several thousand glucose residues; amylose is a polysaccharide chain in which D-glucose groups are connected by a-(1,4) glycosidic bonds, and has about 200 glucose groups in the molecule, with a molecular weight of 1 to 2×10 5 , degree of polymerization 990, spatial conformation curled into a spiral, each turn is 6 glucose groups. Amylopectin and amylose, the two starch chemical structures are different, amylose is basically linear, while amylopectin is highly branched. Amylopectin provides multiple sites for α-amylase in the duodenum; on the contrary, amylose chains tend to recombine in a double helix structure and are not easy to bind to α-amylase; therefore, the relative content of the two starches will affect the properties and functions of starch carbohydrates; carbohydrates with a higher amylose content are digested more slowly, which can delay the increase in blood sugar and insulin concentrations after a meal. The low glycemic index dietary composition of the present invention, the source of the lower glycemic index is amylose and amylopectin, which can slow down the release of glucose, reduce the peak value and the rise rate of glucose after entering the blood, and make it easier to maintain blood sugar in a relatively stable state.

[0031] The fish oil in the present invention is called Fats and Glyceridic oils in English, with CAS No. 8016-13-5. It is the general name of all oil substances in fish and is derived from the body of large marine fish. Its main component is Omega-3 fatty acids (including DHA and EPA), which are polyunsaturated fatty acids that can reduce inflammatory reactions, lower blood fat, and prevent cardiovascular diseases.

[0032] The flaxseed oil in the present invention is prepared from flaxseeds. The alpha-linolenic acid content in the flaxseed oil is 53%. The alpha-linolenic acid is an essential fatty acid for human body and can be converted into eicosapentaenoic acid and docosahexaenoic acid in human body, which are effective active ingredients in fish oil.

[0033] The best sources of anti-inflammatory Omega-3 fatty acids in the low glycemic index dietary composition of the present invention are fish oil and flaxseed oil.

[0034] According to the length of the carbon chain in the fatty acid molecular structure, fatty acids are divided into three categories: short-chain fatty acids (with less than 6 carbon atoms in the carbon chain), medium-chain fatty acids (with 6 to 12 carbon atoms in the carbon chain) and long-chain fatty acids (with more than 12 carbon atoms in the carbon chain); the medium-chain fatty acid oil of the present invention has 6 to 12 carbon atoms in the carbon chain, preferably 8 carbon atoms.

[0035] The cocoa butter in the present invention is a natural edible oil extracted from cocoa beans; cocoa butter, also known as cocoa butter, is a milky yellow hard natural vegetable oil extracted from cocoa liquor and is a very unique oil.

[0036] The mineral used in the present invention is specifically composite mineral Mineral Mix S10026.

[0037] In the present invention, the cellulose specifically used is Cellulose BW200 cellulose.

[0038] In some embodiments, the low glycemic index dietary composition further comprises: choline bitartrate, L-lysine, L-leucine, L-cystine, L-arabinose, D-ribose, and D-mannose.

[0039] Specifically, L-lysine, English name: L-Lysine, Chinese alias: L-2,6-diaminocaproic acid, L-lysine (edible grade), lysine, is mainly used as a food fortifier.

[0040] Specifically, L-leucine, also known as leucine, has a chemical name of α-aminoisocaproic acid. L-leucine is one of the 18 common amino acids and one of the eight essential amino acids for the human body.

[0041] Specifically, the English name of L-cystine is Cystine, and its number in CAS (Chemical Abstracts International) is 56-89-3. Its common molecular formula is C 6 H 12 N 2 O 4 S 2 , molecular weight is 240.30; L-cystine, a derivative of cysteine, is one of the essential amino acids for the human body. It is used in the food industry as a nutritional enhancer.

[0042] Specifically, L-arabinose, also known as gum aldose and pectinose, is an aldopentose with a chemical formula of C 5 H 10 O 5 L-arabinose, as a low-calorie sweetener, is widely found in the peels of fruits and whole grains. It can inhibit the activity of sucrase in the human intestine, thereby inhibiting the absorption of sucrose.

[0043] Specifically, D-ribose (D-ribose), molecular formula C 5 H 10 O 5D-ribose is an important five-carbon monosaccharide and an important component of ribonucleic acid (RNA) and ATP. It plays an important role in the formation of life. D-ribose is also an important drug intermediate, used in the production of a variety of nucleic acid drugs, and has broad application prospects.

[0044] Specifically, D-mannose, English name: D(+)-Mannose, CAS number: 3458-28-4, molecular formula: C 6 H 12 O 6 .

[0045] In some embodiments, the protein is whey protein, which is a precious protein separated and extracted from milk using advanced technology. It is promoted as the "king of protein" for its many advantages such as high purity, high absorption rate, and the most reasonable amino acid composition. Whey protein is not only easy to digest, but also has high biological value, high efficiency, high protein efficacy ratio and high utilization rate. It is a fine protein and is recognized as one of the high-quality protein supplements for the human body. 87% of milk is water and 13% is milk solids. Among the milk solids, 27% is milk protein, and only 20% of the milk protein is whey protein, and the remaining 80% is casein. Therefore, the content of whey protein in milk is only 0.7%.

[0046] In some embodiments, the medium-chain fatty acid oil is medium-chain fatty acid triglyceride, also known as medium-chain triglyceride. Generally, fatty acids containing 6 to 12 carbon atoms in a carbon chain are called medium-chain fatty acids (MCFA), which are esterified with glycerol to form medium-chain fatty acid triglycerides (or medium-chain triglycerides, MCT).

[0047] In some embodiments, a low glycemic index dietary composition comprises the following components by mass fraction: 24-26% protein, 20-23% starch, 5-7% cellulose, 1-1.6% fish oil, 0.5-1% flaxseed oil, 1-2% medium-chain fatty acid oil, 30-33% cocoa butter, 3-3.5% D-mannose, 1-1.5% minerals, 1.5-2% dicalcium phosphate, 0.5-1% calcium carbonate, 2-2.5% potassium citrate, 0.1-0.2% vitamins, 0.2-0.4% choline bitartrate, 0.3-0.5% L-lysine, 0.3-0.6% L-leucine, 0.1-0.3% L-cystine, 1-2% L-arabinose, and 0.4-0.65% D-ribose.

[0048] In some embodiments, a low glycemic index dietary composition comprises the following components by mass fraction: 24-26% whey protein, 20-23% starch (wherein the starch comprises 70% amylose by mass and 30% amylopectin by mass fraction), 5-7% cellulose, 1-1.6% fish oil, 0.5-1% flaxseed oil, 1-2% C8 MCT oil (i.e., medium-chain fatty acid triglycerides with 8 carbon atoms), 30-33% cocoa butter, 3-3.5% D-mannose, 1-1.5% minerals, 1.5-2% dicalcium phosphate, 0.5-1% calcium carbonate, 2-2.5% potassium citrate, 0.1-0.2% vitamins, 0.2-0.4% choline bitartrate, 0.3-0.5 L-lysine, 0.3-0.6% L-leucine, 0.1-0.3% L-cystine, 1-2% L-arabinose, 0.4-0.65% D-ribose.

[0049] In some embodiments, the vitamin is vitamin C, specifically V10001C.

[0050] In some embodiments, the carbon atom in the carbon chain of the medium-chain fatty acid oil is 8. Specifically, the medium-chain fatty acid triglyceride is a medium-chain triglyceride with 8 carbon atoms. The medium-chain triglyceride can improve ketone body production.

[0051] In some embodiments, the starch includes amylose and amylopectin, wherein the mass ratio of amylose to amylopectin is (60-80):(20-40).

[0052] The low glycemic index dietary composition of the present invention can generate a lower glycemic index and is anti-inflammatory, and the essential amino acids, vitamins and minerals rich in the composition are helpful for the intake and absorption of nutrients, and most importantly, can improve the aggressive behavior of autistic disorder model mice. The present invention has been proven to be feasible through experiments. By using different model animals for testing, it was found that the aggressive behavior of different model mice after consuming LGID was significantly different from that of blank control group mice. The experimental analysis results are reliable, the system error is small, and the experimental efficiency is high. The low glycemic index dietary composition of the present invention is based on the problem that most children with autism are picky eaters, and fully considers the comprehensiveness of nutrients and the palatability of food. It can not only meet the supplementation of different nutrients, but also improve / mitigate the occurrence of aggressive behavior, and provide services for improving the quality of life of patients with autism and a good social environment.

[0053] Based on the same inventive concept, the present invention also provides a method for preparing the above-mentioned low glycemic index dietary composition, comprising the following steps:

[0054] After mixing the raw materials of the low glycemic index dietary composition, water is added, stirred, granulated, and dried to obtain the low glycemic index dietary composition.

[0055] In some embodiments, the ingredients of the low glycemic index dietary composition are mixed, water is added, stirred, granulated, and then the granulated material is irradiated with gamma rays to obtain a low glycemic index dietary composition.

[0056] In some embodiments, a method for preparing a low glycemic index dietary composition comprises the following steps:

[0057] S1. Mix the raw materials of each component in the low glycemic index diet composition, then add sterile water, and stir thoroughly to obtain a mass;

[0058] S2, granulating the agglomerates in S1 into granules with a diameter of 12.5 mm and a length of 4 cm to obtain granules;

[0059] S3, placing the granules in S2 in a drying device and drying for 1 to 2 days;

[0060] S4, irradiating the dried granules in S3 with gamma rays for 1 to 2 days;

[0061] S5. Aseptically packing the irradiated granules to obtain a low glycemic index dietary composition.

[0062] Based on the same inventive concept, the present invention also provides a use of the low glycemic index dietary composition or the low glycemic index dietary composition prepared by the above preparation method in the preparation of a drug for improving aggressive behavior in autistic disorder.

[0063] The following further illustrates the low glycemic index dietary composition of the present application and its preparation method and application with specific examples. This section further illustrates the content of the present invention in conjunction with specific examples, but should not be construed as limiting the present invention. Unless otherwise specified, the technical means used in the embodiments are conventional means well known to those skilled in the art. Unless otherwise specified, the reagents, methods and equipment used in the present invention are conventional reagents, methods and equipment in the art.

[0064] Example 1

[0065] The embodiment of the present application provides a low glycemic index dietary composition, comprising the following components by mass fraction: 25.20% whey protein, 21.19% starch, 6.50% cellulose, 1.30% fish oil, 0.65% linseed oil, 1.30% medium-chain fatty acid oil, 31.66% cocoa butter, 3.22% D-mannose, 1.30% minerals, 1.68% dicalcium phosphate, 0.71% calcium carbonate, 2.13% potassium citrate, 0.13% vitamins, 0.26% choline bitartrate, 0.39% L-lysine, 0.45% L-leucine, 0.19% L-cystine, 1.30% L-arabinose, and 0.44% D-ribose.

[0066] Among them, the protein is whey protein; the starch includes a mixture of 70% by mass of amylose and 30% by mass of amylopectin; the cellulose is Cellulose BW200 cellulose; the medium-chain fatty acid oil is a medium-chain fatty acid triglyceride with 8 carbon atoms (i.e., C8 MCT oil); the mineral is the complex mineral Mineral Mix S10026; and the vitamin is vitamin C, specifically V10001C.

[0067] The method for preparing the low glycemic index dietary composition comprises the following steps:

[0068] S1. According to the above ratio, the raw materials of each component of the low glycemic index diet composition are mixed, and then sterile water is added, and the mixture is fully stirred to obtain a mass;

[0069] S2, forming the agglomerate in S1 into granules with a diameter of 12.5 mm and a length of 4 cm to obtain granules;

[0070] S3, placing the granules in S2 in a drying device and drying for 2 days;

[0071] S4, irradiating the dried granules in S3 with gamma rays for 2 days;

[0072] S5. Aseptically packing the irradiated granules to obtain a low glycemic index dietary composition.

[0073] Performance Testing

[0074] The effects of the low glycemic index dietary composition prepared in Example 1 of the present invention and ordinary feed on the weight of mice, the total number of aggressive behaviors of mice, and the percentage of aggressive behaviors of mice were tested respectively. The results are as follows: Figures 1 to 4 shown. Figures 1 to 4 The medium LGID feed is the low glycemic index dietary composition prepared in Example 1 of the present invention. Figures 1 to 4The control mice-normal feed and the control mice-LGID feed represent that the wild-type mice were fed with normal feed and the low glycemic index diet composition prepared in Example 1, respectively. Figures 1 to 4 Autistic disorder mice-normal feed and autistic disorder mice-LGID feed respectively represent that autistic disorder model mice were fed with normal feed and the low glycemic index diet composition prepared in Example 1.

[0075] The specific test method is as follows:

[0076] MECP2 overexpression autism model mice and wild-type mice were selected as experimental subjects. Conventional feeding conditions were used and different diets were intervened at 6 weeks of age. The experiment was divided into 4 groups, including: 1) fed with ordinary feed: ordinary feed-wild-type mice; ordinary feed-autism model mice; 2) fed with LGID feed: LGID feed-wild-type mice; LGID feed-autism model mice. The intervention period was 33 days, during which the weight of mice fed with LGID was monitored, weighed every 2 days, and statistically analyzed. The results are shown in the figure. Figure 2 As shown. Figure 2 It can be seen that the LGID diet intervention has little effect on the weight of wild mice and autism model mice, and there is no difference. In the circular open field box, black C57 BL / 6J mice were used as the social interaction objects of the target mice. Their social activities were observed for 15 minutes, and the total number of attacks and the percentage of time spent on attacks were counted. The results are as follows Figures 3-4 After the behavioral test, the blood glucose levels were measured and compared after fasting for 16 hours. The results are shown in Figure 1 As shown in the results, it was found that after fasting for 16 hours, the blood glucose level of mice fed with LGID was higher than that of mice fed with ordinary feed, indicating that this kind of feed is easy to maintain a stable blood sugar level. Figures 2 to 4 As can be seen, LGID diet had no effect on the body weight of the test mice ( Figure 2 ) and can improve the aggressive behavior of autism model mice ( Figure 3-4 ).

[0077] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A low glycemic index dietary composition, characterized in that: The invention comprises the following components: protein, starch, cellulose, fish oil, linseed oil, medium-chain fatty acid oil, cocoa butter, minerals, dicalcium phosphate, calcium carbonate, potassium citrate and vitamins; wherein the starch comprises straight-chain starch and amylopectin.

2. The low glycemic index dietary composition according to claim 1, characterized in that Also includes: Choline bitartrate, L-lysine, L-leucine, L-cystine, L-arabinose, D-ribose, D-mannose.

3. The low glycemic index dietary composition according to claim 1, wherein The protein is whey protein.

4. The low glycemic index dietary composition according to claim 1, wherein The medium-chain fatty acid oil is medium-chain fatty acid triglyceride.

5. The low glycemic index dietary composition according to claim 2, characterized in that: The invention comprises the following components in mass fraction: 24-26% protein, 20-23% starch, 5-7% cellulose, 1-1.6% fish oil, 0.5-1% linseed oil, 1-2% medium-chain fatty acid oil, 30-33% cocoa butter, 3-3.5% D-mannose, 1-1.5% minerals, 1.5-2% dicalcium phosphate, 0.5-1% calcium carbonate, 2-2.5% potassium citrate, 0.1-0.2% vitamins, 0.2-0.4% choline bitartrate, 0.3-0.5% L-lysine, 0.3-0.6% L-leucine, 0.1-0.3% L-cystine, 1-2% L-arabinose and 0.4-0.65% D-ribose.

6. The low glycemic index dietary composition according to claim 4, characterized in that: The vitamin is vitamin C; the carbon chain of the medium-chain fatty acid triglyceride has 8 carbon atoms.

7. The low glycemic index dietary composition according to any one of claims 1 to 6, characterized in that: The starch includes amylose and amylopectin, wherein the mass ratio of amylose to amylopectin is (60-80):(20-40).

8. A method for preparing a low glycemic index dietary composition according to any one of claims 1 to 7, characterized in that: The following steps are involved: After mixing the raw materials of the low glycemic index dietary composition, water is added, stirred, granulated, and dried to obtain the low glycemic index dietary composition.

9. The method for preparing the low glycemic index dietary composition according to claim 8, characterized in that: After mixing the raw materials in the low glycemic index dietary composition, water is added, stirred, granulated, and then the granulated material is irradiated under gamma rays to obtain the low glycemic index dietary composition.

10. Use of the low glycemic index dietary composition according to any one of claims 1 to 7 or the low glycemic index dietary composition prepared by the preparation method according to any one of claims 8 to 9 in preparing a drug for improving aggressive behavior in autistic disorder.

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