Anti-allergic cosmetic composition containing sodium gualenate active ingredient

Abstract

The invention provides an anti-allergic cosmetic composition containing sodium gualenate as an active ingredient. The composition comprises sodium gualenate, sodium gualenate and a surfactant, the surfactant is selected from PEG-7 olive oil sodium carboxylate; dipotassium glycyrrhizinate; phenoxyethanol, vitamin E; hyaluronic acid and the balance of deionized water are used as solvents; according to the cosmetic composition, the stability of the sodium gualenate is improved, the skin irritation caused by the sodium gualenate is reduced and the sodium gualenate is prevented from being allergic to a small number of sensitive skin while the effective components of the sodium gualenate have the effects of resisting inflammation, resisting allergy and repairing and regenerating.

Description

Technical Field

[0001] The invention relates to the field of cosmetics, in particular to an anti-allergic cosmetic composition comprising sodium azulene sulfonate as an effective ingredient. Background Art

[0002] Sodium azulene sulfonate is a natural ingredient extracted from Asteraceae plants. Due to its significant anti-inflammatory, anti-allergic and wound healing properties, it is widely used in the cosmetics field, including but not limited to anti-inflammatory and anti-allergic, skin soothing, repair and regeneration, anti-oxidation, radiation protection, etc. It is often added to eye creams, facial masks, creams and other products.

[0003] However, sodium azulene sulfonate also has some problems during application, such as poor stability, easy to cause skin irritation, etc. First, sodium azulene sulfonate contains sulfonic acid group (-SO3H) and azulene ring structure, which are prone to chemical reaction under illumination, air oxidation and high temperature environment, leading to decomposition, so the stability is poor, affecting its efficacy. Secondly, sodium azulene sulfonate has certain skin irritation, which may cause adverse reactions such as skin redness, swelling, itching, especially for patients with sensitive muscles, but becomes an allergen. In the existing technology, there is no effective solution for the problem of how to prevent sodium azulene sulfonate from being allergic to a few sensitive muscles. Therefore, how to improve the stability of sodium azulene sulfonate, reduce the skin irritation it brings, and prevent sodium azulene sulfonate from being allergic to a few sensitive muscles while ensuring that the effective ingredient of sodium azulene sulfonate has anti-inflammatory and anti-allergic effects, repair and regenerate effects, is the main problem facing current technology. Summary of the invention

[0004] In order to solve the problems in the prior art, the present invention improves the stability of sodium azulene sulfonate, reduces skin irritation, prevents allergic reactions, and ensures the safety and effectiveness of the cosmetic composition by adding specific surfactants, dipotassium glycyrrhizinate, vitamin E, hyaluronic acid, phenoxyethanol and other ingredients to sodium azulene sulfonate.

[0005] The specific plan is as follows:

[0006] An anti-allergic cosmetic composition containing sodium azulene sulfonate as an effective ingredient, the composition comprising:

[0007] a. Sodium azulene sulfonate;

[0008] b. a surfactant selected from sodium PEG-7 olive oil carboxylate;

[0009] c. Dipotassium glycyrrhizinate;

[0010] d. Phenoxyethanol;

[0011] e. Vitamin E;

[0012] f. Hyaluronic acid;

[0013] g. The balance is deionized water as solvent.

[0014] In one embodiment, based on 100 wt% of the total weight of the composition, the amount of sodium azulene sulfonate added is 0.01 wt% to 0.1 wt%, preferably 0.02 wt to 0.05 wt%.

[0015] In one embodiment, based on 100 wt% of the total weight of the composition, the added amount of the surfactant is 0.5 wt% to 2 wt%, preferably 0.8 wt% to 1.5 wt%.

[0016] In one embodiment, based on 100 wt% of the total weight of the composition, the added amount of dipotassium glycyrrhizinate is 0.1 wt% to 1 wt%, preferably 0.2 wt% to 0.5 wt%.

[0017] In one embodiment, based on 100 wt% of the total weight of the composition, the amount of phenoxyethanol added is 0.01 wt% to 0.5 wt%, preferably 0.05 wt% to 0.3 wt%.

[0018] In one embodiment, based on 100 wt% of the total weight of the composition, the added amount of vitamin E is 0.05 wt% to 0.5 wt%, preferably 0.1 wt% to 0.3 wt%.

[0019] In one embodiment, based on 100 wt% of the total weight of the composition, the amount of hyaluronic acid added is 0.1 wt% to 2 wt%, preferably 0.5 wt% to 1 wt%.

[0020] In one embodiment, the composition further comprises at least one of the following additional ingredients:

[0021] h. a preservative selected from sodium benzoate, potassium sorbate or parabens;

[0022] i. an antioxidant selected from butylated hydroxyanisole, butylated hydroxytoluene or tocopherol;

[0023] j.spices;

[0024] k. Pigment.

[0025] In one embodiment, the antiallergic cosmetic composition is used to prepare a cosmetic preparation, and the cosmetic preparation is selected from ointment, cream, gel, spray or solution.

[0026] The present invention also discloses a method for preparing an anti-allergic cosmetic composition containing sodium azulene sulfonate as an effective ingredient, comprising the following steps:

[0027] (1) dissolving sodium azulene sulfonate in purified water;

[0028] (2) adding surfactant, dipotassium glycyrrhizinate, vitamin E, hyaluronic acid and phenoxyethanol respectively;

[0029] (3) Stir and mix well at 20-30°C.

[0030] The invention also discloses use of an anti-allergic cosmetic composition containing the sodium azulene sulfonate effective ingredient as a component of a skin care product.

[0031] Based on the above scheme, the present invention has the following beneficial effects:

[0032] First, the solution according to the present invention can enhance the stability of sodium azulene sulfonate in cosmetic preparations. By adding a specific surfactant PEG-7 olive oil carboxylate sodium, the decomposition of sodium azulene sulfonate during storage and use can be reduced, especially under light, air oxidation and high temperature environments, thereby ensuring the pharmacological stability and durability of sodium azulene sulfonate. It is speculated that the olive oil carboxylate sodium forms a protective film on the surface of sodium azulene sulfonate, which, on the one hand, improves the uniform distribution of sodium azulene sulfonate in the solution and reduces the situation of excessive local concentration. On the other hand, the protective film formed protects the sodium azulene sulfonate molecules from light-induced photolysis by absorbing or reflecting light, and may reduce oxidation reactions by capturing free radicals or providing a stable oxygenated environment.

[0033] Secondly, the present invention effectively reduces the skin irritation that may be caused by sodium azulene sulfonate by adding dipotassium glycyrrhizinate, vitamin E and hyaluronic acid. Dipotassium glycyrrhizinate has anti-inflammatory and anti-allergic effects, vitamin E has antioxidant and moisturizing effects, and hyaluronic acid can promote the repair and regeneration of skin cells. These ingredients work together to reduce the potential stimulation of sodium azulene sulfonate to sensitive skin and improve its skin compatibility. And phenoxyethanol, as a commonly used preservative, is added to the composition to extend the shelf life of the product and prevent microbial contamination, thereby ensuring the safety of the product. In addition, by accurately controlling the addition amount of each component, the composition of the present invention can reduce allergic reactions to sensitive skin, particularly for patients with a small number of sensitive skins, providing a safer anti-allergic cosmetics selection.

[0034] The anti-allergic cosmetic composition of the present invention can be used to prepare various cosmetic preparations, such as ointments, creams, gels, sprays or solutions, etc., and has wide adaptability, and can be prepared into different dosage forms as needed to meet the needs of different consumers. In addition, the preparation method of the anti-allergic cosmetic composition of the present invention is simple and easy, easy to operate, and has low production cost, which is conducive to large-scale production and use. DETAILED DESCRIPTION

[0035] Although the present invention has been described to a certain extent, it is obvious that appropriate changes in various conditions can be made without departing from the spirit and scope of the present invention. It is understood that the present invention is not limited to the embodiments described, but belongs to the scope of the claims, which includes equivalent replacements of each factor described.

[0036] The anti-allergic cosmetic composition of the present invention generally contains soothing and repairing ingredients, which are helpful to relieve redness, itching and other allergic symptoms, and promote the repair of the skin barrier. In the present invention, the soothing and repairing active ingredients are mainly sodium azulene sulfonate, which is a compound with anti-inflammatory and repairing and regeneration functions, and contains sulfonic acid group (-SO3H) and azulene ring structure in its structure. These groups give it the ability to interact with biomacromolecules, thereby exerting an anti-inflammatory effect. Sodium azulene sulfonate can inhibit the release of inflammatory factors, and promote the formation of granulation and epithelial tissue, helping to repair damaged tissue. However, the stability of sodium azulene sulfonate is relatively poor, mainly because the sulfonic acid group and azulene ring structure it contains are prone to chemical reactions under light, air oxidation and high temperature environments, resulting in decomposition, thereby losing efficacy. In addition, sodium azulene sulfonate is chemically unstable and easy to remove the sulfonic acid group. For a small number of people with sensitive skin, sodium azulene sulfonate may cause skin irritation. This may be due to the potential irritation caused by its chemical structure, or because some individuals have allergic reactions to certain ingredients in sodium azulene sulfonate. Patients with sensitive skin syndrome (SSS) have skin that is more sensitive to some substances and may experience symptoms such as tingling, itching, and burning. Based on the total weight of the composition of 100wt%, the amount of sodium azulene sulfonate added is 0.01wt% to 0.1wt%, preferably 0.02wt to 0.05wt%. This range ensures that sodium azulene sulfonate can effectively exert its anti-inflammatory and repair effects while avoiding skin irritation that may be caused by excessively high concentrations.

[0037] In order to improve the stability of sodium azulene sulfonate, a specific surfactant, such as PEG-7 olive oil carboxylate, is usually added. This surfactant can form a protective film around the molecules of sodium azulene sulfonate, reducing the damage to its structure caused by light and oxidation, thereby improving its stability. The molecular structure of PEG-7 olive oil carboxylate contains a hydrophilic head (PEG) and a lipophilic tail (olive acid), which enables it to form a stable emulsion layer between the aqueous phase and the oil phase, thereby protecting the sodium azulene sulfonate from being destroyed by external environmental factors. Based on the total weight of the composition of 100wt%, the addition amount of the surfactant is 0.5wt% to 2wt%, preferably 0.8wt% to 1.5wt%. Within this concentration range, the surfactant will not affect the overall stability and skin compatibility of the cosmetics while improving the stability of sodium azulene sulfonate.

[0038] Dipotassium glycyrrhizinate is an ingredient with anti-inflammatory and anti-allergic effects, which can reduce the skin irritation that may be caused by sodium azulene sulfonate. The anti-inflammatory effect of dipotassium glycyrrhizinate is mainly through inhibiting the production of inflammatory factors, such as prostaglandins and leukotrienes, which play a key role in inflammatory reactions. In addition, dipotassium glycyrrhizinate can also stabilize cell membranes and reduce the release of histamine, thereby alleviating allergic reactions. In cosmetics, the addition amount of dipotassium glycyrrhizinate is usually controlled within a certain range to ensure that it does not cause skin irritation while having anti-inflammatory and anti-allergic effects. The addition amount of the dipotassium glycyrrhizinate is 0.1wt% to 1wt%, preferably 0.2wt% to 0.5wt%.

[0039] Phenoxyethanol is a commonly used preservative that can extend the shelf life of products and prevent microbial contamination, thereby ensuring the safety of products. The preservative effect of phenoxyethanol is mainly to destroy the cell membrane of microorganisms and make them inactive. At the same time, phenoxyethanol is also an effective stabilizer that can form a stable complex with other ingredients in cosmetics to prevent these ingredients from decomposing or deteriorating during storage and use. The addition of phenoxyethanol not only improves the safety of the product, but also helps to maintain the stability of cosmetics. The addition amount of the phenoxyethanol is 0.01wt% to 0.5wt%, preferably 0.05wt% to 0.3wt%. Phenoxyethanol can effectively inhibit the growth of microorganisms at low concentrations, so the concentration used in cosmetics is usually low.

[0040] Vitamin E is an antioxidant that can protect sodium azulene sulfonate from oxidation and enhance its stability. Vitamin E can also prevent free radicals from damaging cell membranes and DNA by capturing free radicals. In addition, vitamin E can also promote skin repair and accelerate wound healing. The molecular structure of vitamin E contains an active phenolic hydroxyl group that can react with free radicals to protect skin cells from oxidative damage. In cosmetics, the addition of vitamin E not only improves the antioxidant capacity of the product, but also helps repair damaged skin and promote wound healing. The amount of vitamin E added is 0.05wt% to 0.5wt%, preferably 0.1wt% to 0.3wt%.

[0041] Hyaluronic acid has moisturizing and repairing effects, can reduce the skin dryness and irritation that may be caused by sodium azulene sulfonate, and promote the repair and regeneration of skin cells. Hyaluronic acid is a macromolecular polysaccharide that can absorb and lock a large amount of water, form a moisturizing layer, and reduce the loss of skin moisture. In addition, hyaluronic acid can also promote the proliferation and migration of skin cells and accelerate wound healing. The molecular structure of hyaluronic acid contains a large number of carboxyl groups, which can bind to proteins on the surface of the skin to form a stable hydration layer, thereby providing moisturizing and repairing effects. The addition amount of the hyaluronic acid is 0.1wt% to 2wt%, preferably 0.5wt% to 1wt%.

[0042] The combination of these ingredients not only solves the stability problem of sodium azulene sulfonate, but also significantly reduces its irritation to sensitive skin. Surfactants and phenoxyethanol improve stability, dipotassium glycyrrhizinate and vitamin E provide anti-inflammatory and repair effects, hyaluronic acid enhances moisturizing and repair effects, and deionized water ensures the purity and stability of the overall formula. This synergistic effect makes the cosmetic composition safer and more effective, suitable for use on sensitive skin. Through precise formula design and ingredient selection, this cosmetic composition can provide consumers with a safe and effective skin care option to meet the needs of healthy skin.

[0043] In the cosmetic composition, in addition to the main active ingredients and stabilizers, some additional ingredients are also included to enhance the performance and sensory experience of the product. These additional ingredients include preservatives, antioxidants, fragrances and pigments. Preservatives such as sodium benzoate, potassium sorbate or parabens are used to extend the shelf life of the product, prevent microbial growth and contamination, and ensure the safety of the product. Antioxidants such as butylated hydroxyanisole, dibutyl hydroxytoluene or tocopherol help protect the active ingredients in the product from oxidation damage and maintain the stability and effectiveness of the product. Fragrances are used to add a pleasant smell to the product and enhance the consumer's experience. Pigments are used to adjust the color of the product to make it more attractive or meet specific aesthetic requirements. The addition of these additional ingredients, although usually small in content, plays an important role in improving the overall quality of the product and the sensory experience of consumers. It should be noted that when selecting additional ingredients, the anti-allergic effect of cosmetics needs to be considered as a whole, and ingredients that have additional irritation to the skin or affect the repair function cannot be selected.

[0044] The antiallergic cosmetic composition is used for preparing a cosmetic preparation, and the cosmetic preparation is selected from ointment, cream, gel, spray or solution.

[0045] The present invention also discloses a method for preparing an anti-allergic cosmetic composition containing sodium azulene sulfonate as an effective ingredient, comprising the following steps:

[0046] (1) dissolving sodium azulene sulfonate in purified water;

[0047] (2) adding surfactant, dipotassium glycyrrhizinate, vitamin E, hyaluronic acid and phenoxyethanol respectively;

[0048] (3) Stir and mix well at 20-30°C.

[0049] The above steps are conventional steps of mixing to obtain a composition in the art, and are technical solutions that can be generally mastered by those skilled in the art.

[0050] The oral care liquid composition and the preparation method thereof provided by the present invention are described in detail below in conjunction with the examples, but they should not be construed as limiting the scope of protection of the present invention. In addition, if no specific conditions are specified in the examples of the present invention, the conventional conditions or the conditions recommended by the manufacturer are used; if the manufacturer of the reagents or instruments is not specified, they are all conventional products that can be purchased commercially.

[0051] Embodiment 1:

[0052] Table 1 is the ingredient list of Example 1:

[0053] Element content Sodium azulene sulfonate 0.03g Sodium PEG-7 Olive Oil Carboxylate 1g Dipotassium glycyrrhizinate 0.3g Phenoxyethanol 0.2g Vitamin E 0.2g Hyaluronic acid 0.8g Deionized water 96.67g

[0054] The specific preparation process is: dissolve sodium azulene sulfonate in purified water; add PEG-7 olive oil carboxylic acid sodium, dipotassium glycyrrhizinate, vitamin E, hyaluronic acid and phenoxyethanol according to the ratio; stir and mix evenly at 25°C to obtain the product.

[0055] Embodiment 2:

[0056] Table 2 is the ingredient list of Example 2:

[0057] Element content Sodium azulene sulfonate 0.03g Sodium PEG-7 Olive Oil Carboxylate 1g Dipotassium glycyrrhizinate 0.3g Phenoxyethanol 0.2g Vitamin E 0.2g Hyaluronic acid 0.8g Sodium Benzoate 0.1g Butylated Hydroxytoluene 0.05g peppermint 0.2g Deionized water 95.87g

[0058] The specific preparation process is: dissolve sodium azulene sulfonate in purified water; add PEG-7 olive oil carboxylic acid sodium, dipotassium glycyrrhizinate, vitamin E, hyaluronic acid, phenoxyethanol, sodium benzoate, butylated hydroxytoluene and peppermint oil according to the proportions; stir and mix evenly at 25°C to obtain the product.

[0059] Embodiment 3:

[0060] Table 3 is the ingredient list of Example 3:

[0061] Element content Sodium azulene sulfonate 0.1g Sodium PEG-7 Olive Oil Carboxylate 2g Dipotassium glycyrrhizinate 1g Phenoxyethanol 0.5g Vitamin E 0.5g Hyaluronic acid 2g Deionized water 93.9g

[0062] The specific preparation process is: dissolve sodium azulene sulfonate in purified water; add PEG-7 olive oil carboxylic acid sodium, dipotassium glycyrrhizinate, vitamin E, hyaluronic acid and phenoxyethanol according to the ratio; stir and mix evenly at 25°C to obtain the product.

[0063] Embodiment 4:

[0064] Table 4 is the ingredient list of Example 4:

[0065] Element content Sodium azulene sulfonate 0.02g Sodium PEG-7 Olive Oil Carboxylate 0.5g Dipotassium glycyrrhizinate 0.1g Phenoxyethanol 0.02g Vitamin E 0.05g Hyaluronic acid 0.1g Deionized water 99.21g

[0066] The specific preparation process is: dissolve sodium azulene sulfonate in purified water; add PEG-7 olive oil carboxylic acid sodium, dipotassium glycyrrhizinate, vitamin E, hyaluronic acid and phenoxyethanol according to the ratio; stir and mix evenly at 25°C to obtain the product.

[0067] Comparative Example 1:

[0068] Table 5 is the ingredient list of Comparative Example 1:

[0069] Element content Sodium PEG-7 Olive Oil Carboxylate 1g Dipotassium glycyrrhizinate 0.3g Phenoxyethanol 0.2g Vitamin E 0.2g Hyaluronic acid 0.8g Deionized water 96.7g

[0070] The specific preparation process is: add PEG-7 olive oil carboxylic acid sodium, dipotassium glycyrrhizinate, vitamin E, hyaluronic acid and phenoxyethanol according to the ratio; stir and mix evenly at 25°C to obtain the product.

[0071] Comparative Example 2:

[0072] Table 6 is the ingredient list of Comparative Example 2:

[0073] Element content Sodium azulene sulfonate 0.03g Dipotassium glycyrrhizinate 0.3g Phenoxyethanol 0.2g Vitamin E 0.2g Hyaluronic acid 0.8g Deionized water 97.67g

[0074] The specific preparation process is: dissolve sodium azulene sulfonate in purified water; add dipotassium glycyrrhizinate, vitamin E, hyaluronic acid and phenoxyethanol according to the ratio; stir and mix evenly at 25°C to obtain the product.

[0075] Comparative Example 3:

[0076] Table 7 is the ingredient list of Comparative Example 3:

[0077] Element content Sodium azulene sulfonate 0.03g Sodium PEG-7 Olive Oil Carboxylate 1g Phenoxyethanol 0.2g Vitamin E 0.2g Hyaluronic acid 0.8g Deionized water 96.97g

[0078] The specific preparation process is: dissolve sodium azulene sulfonate in purified water; add sodium PEG-7 olive oil carboxylate, vitamin E, hyaluronic acid and phenoxyethanol according to the ratio; stir and mix evenly at 25°C to obtain the product.

[0079] Comparative Example 4:

[0080] Table 8 is the ingredient table of Comparative Example 4:

[0081] Element content Sodium azulene sulfonate 0.03g Sodium PEG-7 Olive Oil Carboxylate 1g Dipotassium glycyrrhizinate 0.3g Vitamin E 0.2g Hyaluronic acid 0.8g Deionized water 96.87g

[0082] The specific preparation process is: dissolve sodium azulene sulfonate in purified water; add PEG-7 olive oil carboxylic acid sodium, dipotassium glycyrrhizinate, vitamin E and hyaluronic acid according to the ratio; stir and mix evenly at 25°C to obtain the product.

[0083] Comparative Example 5:

[0084] Table 9 is the ingredient list of Comparative Example 5:

[0085] Element content Sodium azulene sulfonate 0.03g Sodium PEG-7 Olive Oil Carboxylate 1g Dipotassium glycyrrhizinate 0.3g Phenoxyethanol 0.2g Hyaluronic acid 0.8g Deionized water 96.87g

[0086] The specific preparation process is: dissolve sodium azulene sulfonate in purified water; add PEG-7 olive oil carboxylic acid sodium, dipotassium glycyrrhizinate, hyaluronic acid and phenoxyethanol according to the ratio; stir and mix evenly at 25°C to obtain the product.

[0087] Comparative Example 6:

[0088] Table 10 is the ingredient table of Comparative Example 6:

[0089] Element content Sodium azulene sulfonate 0.03g Sodium PEG-7 Olive Oil Carboxylate 1g Dipotassium glycyrrhizinate 0.3g Phenoxyethanol 0.2g Vitamin E 0.2g Deionized water 97.47g

[0090] The specific preparation process is: dissolve sodium azulene sulfonate in purified water; add PEG-7 olive oil carboxylic acid sodium, dipotassium glycyrrhizinate, vitamin E and phenoxyethanol according to the ratio; stir and mix evenly at 25°C to obtain the product.

[0091] Test experiment:

[0092] 1- Accelerated stability test experiment

[0093] 10 ml of each of the cosmetic compositions of Examples 1-4 and Comparative Examples 1-6 were taken and packaged in open containers, and then placed in an environment of 40°C ± 2°C and 75% ± 5% relative humidity. 1 ml of samples were taken out at 1 day, 5 days, 10 days, 30 days and 60 days, respectively, to evaluate the effective content of sodium azulene sulfonate. The percentage of the content of sodium azulene sulfonate in the samples compared to the initial content was analyzed by HPLC high performance liquid chromatography to confirm its decomposition.

[0094] Table 9 shows the results of the accelerated stability test:

[0095]

[0096]

[0097] It can be seen that in the process of stabilizing sodium azulene sulfonate, PEG-7 olive oil carboxylic acid sodium, phenoxyethanol and vitamin E all play corresponding roles together. When any one of these ingredients is missing, sodium azulene sulfonate will be unstable during long-term storage.

[0098] 2-Skin irritation and repair test

[0099] 220 volunteers whose skin was confirmed to be sensitive by dermatologists were recruited, and the subjects were guaranteed not to use other skin care products that might affect the results during the test period.

[0100] The subjects were randomly divided into 11 groups, with 20 people in each group; Groups 1-4 used the samples of Examples 1-4, Groups 5-10 used the samples of Comparative Examples 1-6, and Group 11 was a control group that used deionized water.

[0101] Each group of subjects was given a designated product and provided with detailed instructions to ensure that all subjects used the product correctly. The subjects used the sample once in the morning and once in the evening.

[0102] Before the test, the subjects' skin condition data were collected, including skin erythema, dryness, and sensitivity. Four weeks after using the samples, the subjects' skin conditions were evaluated again, and the subjects' final feedback and product preferences were collected, and statistical analysis was performed on the test results.

[0103] Table 10 shows the skin condition feedback before and after the test (4 weeks)

[0104]

[0105]

[0106] It can be seen that compared with comparative examples 1-6 and the control group, Examples 1-4 have obvious improvements in skin erythema elimination and inhibition, skin soothing and skin repair, and due to the reasonable combination of the formula, the samples themselves will not cause skin discomfort to people with sensitive skin.

[0107] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit it. Although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present application.

Claims

1. An anti-allergic cosmetic composition comprising sodium azulene sulfonate as an effective ingredient, characterized in that: The composition comprises: a. Sodium azulene sulfonate; b. a surfactant selected from sodium PEG-7 olive oil carboxylate; c. Dipotassium glycyrrhizinate; d. Phenoxyethanol; e. Vitamin E; f. Hyaluronic acid; g. The balance is deionized water as solvent.

2. The antiallergic cosmetic composition according to claim 1, characterized in that: Based on 100 wt % of the total weight of the composition, the added amount of the sodium azulene sulfonate is 0.01 wt % to 0.1 wt %.

3. The anti-allergic cosmetic composition according to claim 1, characterized in that: Based on 100 wt % of the total weight of the composition, the added amount of the surfactant is 0.5 wt % to 2 wt %.

4. The antiallergic cosmetic composition according to claim 1, characterized in that: Based on 100 wt % of the total weight of the composition, the added amount of dipotassium glycyrrhizinate is 0.1 wt % to 1 wt %.

5. The antiallergic cosmetic composition according to claim 1, characterized in that: Based on 100 wt % of the total weight of the composition, the added amount of phenoxyethanol is 0.01 wt % to 0.5 wt %.

6. The antiallergic cosmetic composition according to claim 1, characterized in that: Based on 100 wt % of the total weight of the composition, the added amount of vitamin E is 0.05 wt % to 0.5 wt %.

7. The antiallergic cosmetic composition according to claim 1, characterized in that: Based on 100 wt % of the total weight of the composition, the added amount of the hyaluronic acid is 0.1 wt % to 2 wt %.

8. The antiallergic cosmetic composition according to claim 1, characterized in that: The composition further comprises at least one of the following additional ingredients: h. a preservative selected from sodium benzoate, potassium sorbate or parabens; i. an antioxidant selected from butylated hydroxyanisole, butylated hydroxytoluene or tocopherol; j.spices; k. Pigment.

9. The anti-allergic cosmetic composition according to claim 1, characterized in that: The antiallergic cosmetic composition is used for preparing a cosmetic preparation, and the cosmetic preparation is selected from ointment, cream, gel, spray or solution.

10. A method for preparing the anti-allergic cosmetic composition according to claim 1, comprising the following steps: (1) dissolving sodium azulene sulfonate in purified water; (2) adding surfactant, dipotassium glycyrrhizinate, vitamin E, hyaluronic acid and phenoxyethanol respectively; (3) Stir and mix well at 20-30°C.

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