Oral medicament suitable for female irregular menstruation and preparation process thereof

Abstract

The invention discloses an oral medicament suitable for female irregular menstruation and a preparation process thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following materials in parts by mass: 3 to 10 parts of radix bupleuri, 10 to 15 parts of radix paeoniae alba, 10 to 15 parts of rhizoma atractylodis macrocephalae, 10 to 15 parts of poria cocos, 3 to 6 parts of liquorice root, 3 to 6 parts of herba menthae, 10 to 15 parts of radix codonopsis, 10 to 15 parts of herba leonuri, 6 to 10 parts of peach kernel, 6 to 10 parts of flos carthami, 10 to 15 parts of radix rehmanniae preparata, 6 to 10 parts of rhizoma cyperi, 3 to 10 parts of folium artemisiae argyi, 3 to 10 parts of red date and 10 to 15 parts of radix angelicae sinensis. , 3-10 parts by mass of ginger, 2-10 parts by mass of a disintegrating agent and 2-10 parts by mass of an adhesive. According to the oral medicament suitable for female irregular menstruation and the preparation process thereof, radix bupleuri, radix paeoniae alba and rhizoma cyperi are compatible, so that the oral medicament is capable of soothing liver-qi stagnation, nourishing liver and relieving pain, and is often used for related diseases of liver depression and qi stagnation; chinese angelica, prepared rhizome of rehmannia, radix paeoniae alba and codonopsis pilosula are compatible, so that the effects of enriching and nourishing blood can be achieved.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicines, in particular to an oral medicament suitable for treating menstrual disorders in women and a preparation process thereof. Background Art

[0002] Irregular menstruation is a common gynecological problem that troubles many women. It covers a variety of manifestations, including irregular menstrual cycles, abnormal menstrual flow, and different menstrual periods. Its inducing factors are complex and diverse, including endocrine disorders, mental stress, environmental changes, malnutrition, gynecological diseases, etc.

[0003] Long-term menstrual irregularities may lead to a series of serious consequences for women, such as anemia, infertility, and premature aging, which greatly affects women's physical and mental health and quality of life. However, existing treatments and drugs often have certain limitations. Although Western medicine can have a certain effect in the short term, it may bring some adverse reactions and it is difficult to fundamentally improve the physical condition.

[0004] Among them, there are many forms of medicines, and pills are a more common traditional dosage form.

[0005] According to traditional Chinese medicine, menstrual disorders are closely related to qi and blood, and the functions of internal organs. Through the overall conditioning of traditional Chinese medicine, it is expected to achieve the effect of treating both the symptoms and the root causes. However, there are many inconveniences in the use of traditional Chinese medicine preparations, such as troublesome decoction and poor taste. In this context, the development of an oral medicine and its production process that can give full play to the advantages of traditional Chinese medicine, have good palatability and convenience, and can effectively improve women's menstrual disorders is of great significance to meet the health needs of the majority of women. Summary of the invention

[0006] To achieve the above objectives, the present invention is implemented through the following technical scheme: an oral medicament suitable for female menstrual disorders, composed of the following materials: 3-10 parts by mass of bupleurum, 10-15 parts by mass of white peony root, 10-15 parts by mass of atractylodes, 10-15 parts by mass of Poria, 3-6 parts by mass of licorice, 3-6 parts by mass of mint, 10-15 parts by mass of Codonopsis pilosula, 10-15 parts by mass of Leonurus japonicus, 6-10 parts by mass of peach kernel, 6-10 parts by mass of safflower, 10-15 parts by mass of Rehmannia glutinosa, 6-10 parts by mass of Cyperus rotundus, 3-10 parts by mass of Artemisia argyi, 3-10 parts by mass of red dates, 10-15 parts by mass of Angelica sinensis, 3-10 parts by mass of ginger, 2-10 parts by mass of disintegrant and 2-10 parts by mass of binder.

[0007] Preferably, it is composed of the following materials: 6 parts by mass of bupleurum, 12 parts by mass of white peony root, 12 parts by mass of atractylodes, 12 parts by mass of Poria, 5 parts by mass of licorice, 5 parts by mass of mint, 12 parts by mass of Codonopsis pilosula, 12 parts by mass of Leonurus japonicus, 8 parts by mass of peach kernel, 8 parts by mass of safflower, 12 parts by mass of Rehmannia glutinosa, 8 parts by mass of Cyperus rotundus, 8 parts by mass of Artemisia argyi, 8 parts by mass of red dates, 12 parts by mass of Angelica sinensis, 9 parts by mass of ginger, 4 parts by mass of disintegrant and 4 parts by mass of binder.

[0008] The effects of each component are:

[0009] Bupleurum: slightly cold in nature, pungent and bitter in taste. It has the effects of dispersing fever, relieving liver depression, and raising Yang Qi. It is often used to treat colds and fever, alternating cold and heat, chest and flank pain, and irregular menstruation.

[0010] Angelica: Sweet, spicy, warm in nature. It has the effects of nourishing blood, activating blood circulation, regulating menstruation and relieving pain, and moistening the intestines and relieving constipation. It has a good effect on blood deficiency, chlorosis, dizziness and palpitations, irregular menstruation, amenorrhea, dysmenorrhea, and abdominal pain caused by coldness.

[0011] White peony root: bitter, sour, slightly cold. It can nourish blood and regulate menstruation, restrain yin and stop sweating, soften the liver and relieve pain, and suppress liver yang. It can be used for symptoms such as blood deficiency, chlorosis, irregular menstruation, spontaneous sweating, night sweats, flank pain, abdominal pain, etc.

[0012] Atractylodes macrocephala: warm in nature, bitter and sweet in taste. Its main functions are to invigorate the spleen and replenish qi, dry dampness and promote diuresis, stop sweating, and stabilize pregnancy. It is suitable for spleen and stomach qi deficiency, abnormal transportation and transformation, which lead to poor appetite, loose stools, abdominal distension, etc., as well as edema and leucorrhea caused by spleen deficiency and dampness.

[0013] Poria: Sweet, light, neutral in nature. It can promote diuresis and eliminate dampness, strengthen the spleen and calm the mind. It is often used for edema, oliguria, phlegm and fluid, palpitations, spleen deficiency, poor appetite, loose stools, restlessness, palpitations and insomnia.

[0014] Licorice: sweet in taste, neutral in nature. It has the functions of tonifying the spleen and replenishing qi, clearing away heat and detoxifying, removing phlegm and relieving cough, relieving urgency and relieving pain, and harmonizing various medicines. It can be used for spleen and stomach weakness, fatigue, palpitations and shortness of breath, cough and sputum, etc. It plays a harmonizing role in many prescriptions.

[0015] Ginger: spicy, slightly warm. It can dispel cold, warm the middle and stop vomiting, resolve phlegm and stop coughing, and detoxify fish and crabs. It is used for colds, stomach cold vomiting, cold phlegm cough, etc.

[0016] Mint: Cool in nature, spicy in taste. It can dispel wind-heat, clear the head, relieve sore throat and rash, and relieve the liver and promote qi. It has therapeutic effects on wind-heat cold, initial onset of wind-heat, headache, red eyes, throat numbness, mouth sores, etc.

[0017] Codonopsis: sweet in taste, neutral in nature. It has the effects of tonifying the middle and replenishing qi, strengthening the spleen and benefiting the lungs. It is used for shortness of breath, palpitations, loss of appetite, loose stools, asthma and cough caused by spleen and lung qi deficiency.

[0018] Motherwort: slightly cold in nature, bitter and pungent in taste. It can promote blood circulation and regulate menstruation, promote diuresis and reduce swelling, clear away heat and detoxify. It is often used for irregular menstruation, dysmenorrhea, amenorrhea, lochia retention, edema and oliguria.

[0019] Peach kernel: neutral in nature, bitter and sweet in taste. It has the effects of promoting blood circulation, removing blood stasis, moistening the intestines and relieving constipation. It is mainly used for blood stasis syndromes such as amenorrhea, traumatic injury, and constipation caused by dry intestines.

[0020] Safflower: warm in nature, pungent in taste. It has the effects of promoting blood circulation, relieving menstruation, dispersing blood stasis and relieving pain. It is mostly used for amenorrhea, dysmenorrhea, lochia retention, masses, bruises, etc.

[0021] Rehmannia glutinosa: sweet in taste, slightly warm in nature. It can nourish blood and yin, replenish essence and fill marrow. It is suitable for blood deficiency, sallow complexion, palpitations, irregular menstruation, metrorrhagia, liver and kidney yin deficiency, etc.

[0022] Cyperus rotundus: Spicy, slightly bitter, slightly sweet, neutral in nature. It can promote qi and relieve depression, regulate menstruation and relieve pain. It is often used for liver depression and qi stagnation, chest and flank pain, hernia pain, breast pain, irregular menstruation, etc.

[0023] Artemisia argyi: warm in nature, bitter and pungent in taste. Mainly used for warming the meridians and stopping bleeding, dispelling cold and relieving pain, regulating menstruation and stabilizing pregnancy, removing dampness and relieving itching. Can treat vomiting blood, epistaxis, metrorrhagia, menorrhagia, bleeding from the fetus, cold pain in the lower abdomen, etc.

[0024] The combination of Bupleurum, White Peony Root and Cyperus Rhizoma can relieve liver depression, soften liver and relieve pain, and is often used for liver depression and qi stagnation related diseases; the combination of Angelica, Rehmannia glutinosa, White Peony Root and Codonopsis pilosula can nourish blood; the combination of Atractylodes macrocephala, Poria cocos and Licorice can strengthen the spleen and replenish qi, and remove dampness; the combination of peach kernel, safflower and Leonurus japonicus is mainly used to promote blood circulation and remove blood stasis; ginger can harmonize the spleen and stomach, and can also assist in relieving exterior symptoms; mint can clear the head and soothe the liver and promote qi. Mugwort is often used in combination with other drugs to warm the meridians and dispel cold.

[0025] Preferably, the disintegrant is composed of microcrystalline cellulose, cross-linked polyvinyl pyrrolidone and sodium carboxymethyl starch; and the binder is composed of alginate, gelatin and sodium carboxymethyl cellulose.

[0026] A process for preparing an oral medicament for treating irregular menstruation in women, comprising the following steps:

[0027] Step 1, weigh the medicinal materials such as Bupleurum, White Peony, Atractylodes, Poria, Licorice, Mint, Codonopsis, Leonurus, Peach Kernel, Safflower, Rehmannia glutinosa, Cyperus rotundus, Artemisia argyi, and red dates according to the formula ratio, and air-select the medicinal materials to remove impurities and non-medicinal parts, and mix them to obtain mixed medicinal materials A; by weighing and air-selecting, the accurate amount and purity of the medicinal materials are ensured, which provides a good basis for subsequent preparation, and removing impurities can improve the quality of the finished product.

[0028] Step 2: Put the mixed medicinal material A into a traditional Chinese medicine grinder for crushing, and sieve the crushed medicinal material powder to obtain mixed medicinal powder A, and put the mixed medicinal powder A into a traditional Chinese medicine jar; crushing and sieving make the medicinal material into finer powder, increase the surface area, which is conducive to the dissolution and absorption of subsequent ingredients, and putting it into the traditional Chinese medicine jar is convenient for subsequent operations.

[0029] Step 3: Select unspoiled ginger, wash impurities on the surface of the ginger with clean water, and then dry and crush the processed ginger to obtain powder B; process the ginger to obtain powder B to ensure the purity and availability of the ginger and add corresponding efficacy to the formula.

[0030] Step 4: Place the mixed powder A into a mixing tank, gradually add 1.2-1.6 times the amount of water during the mixing and stirring process, and add the disintegrant and binder into the mixing tank after mixing and stirring for 30 minutes to obtain a thick paste; add water and mix and stir to evenly disperse the powder and form a suitable consistency. Adding disintegrants and binders helps the pills to be formed and disintegrated and absorbed in the body.

[0031] Step 5. Wash and dry the surface of the mint, and crush the mint in a traditional Chinese medicine grinder to obtain mint powder, which is then dried for later use. Treat the mint separately to retain its active ingredients, crush it, and dry it for later use.

[0032] Step 6. Heat the thick paste in a heating tank, add mint powder inside, stir and mix, then take out the mixture and put it into a storage tank; adding mint powder and heating and mixing can make the mint ingredients better integrated into the mixture, thereby improving its unique medicinal effect of mint; it also prevents the volatilization of mint ingredients caused by long-term processing of mint.

[0033] Step 7: Dry the mixture in the storage tank and knead it into pills of uniform size through a pill rolling board. The prepared pills are placed on a drying tray and put into a drying oven for drying to obtain finished pills.

[0034] Preferably, the steps of wind selection of Chinese medicinal materials in step 1 are:

[0035] A1. The Chinese medicinal materials to be air-selected are fed into the air-selection chamber through the feeding mechanism;

[0036] A2. The electrostatic generator generates an electrostatic field;

[0037] A3. Under the combined action of airflow and electrostatic field, Chinese medicinal materials are air-selected to separate impurities.

[0038] Preferably, the screening in step 2 is specifically ultrasonic-assisted screening, the ultrasonic frequency of the ultrasonic-assisted screening is 20-40 kHz, the ultrasonic screening time is 5-15 minutes, and the mesh size of the screening is 70-90 mesh.

[0039] Preferably, the specific drying and crushing operation steps of ginger in step 3 are:

[0040] S1. Cut ginger into small pieces, and then evenly spread the cut ginger pieces in a dryer for drying, turning the small pieces of ginger over every ten minutes during the drying process;

[0041] S2, placing the dried ginger pieces on a tray to cool to room temperature for later use;

[0042] S3, putting the cooled dry ginger pieces into a traditional Chinese medicine grinder for grinding, and sieving the ground ginger powder.

[0043] Preferably, in step 4, 1.2-1.6 times the amount of water is divided into four portions, and one portion of water is added to the stirring tank every 5 minutes. The stirring and mixing time of the stirring tank is 1.5-2 hours.

[0044] Preferably, in step 5, the mint is put into the traditional Chinese medicine grinder for 20-30 minutes.

[0045] Preferably, in step six, the thick paste is placed in a heating tank for heating for 1-2 hours at a heating temperature of 60-70 degrees Celsius.

[0046] The present invention provides an oral medicament suitable for treating irregular menstruation in women and its preparation process. It has the following beneficial effects:

[0047] 1. This oral medicine is suitable for women with irregular menstruation. Bupleurum, white peony root and Cyperus rotundus can relieve liver depression, soften liver and relieve pain, and are often used for liver depression and qi stagnation related diseases; Angelica, Rehmannia, white peony root and Codonopsis can nourish blood; Atractylodes, Poria and Licorice can strengthen the spleen and qi, and remove dampness; Peach kernel, safflower and Leonurus can be used to promote blood circulation and remove blood stasis; Ginger can harmonize the spleen and stomach, and can also assist in relieving the symptoms; Mint can clear the head and relieve liver qi. Mugwort is often used with other drugs to warm the meridians and dispel cold.

[0048] 2. This oral medicine suitable for women with irregular menstruation and its production process ensure the accurate amount and purity of medicinal materials through weighing and air selection, providing a good foundation for subsequent preparation. Removing impurities can improve the quality of the finished product.

[0049] 3. The oral medicine suitable for women with menstrual disorders and its production process, through crushing and sieving, the medicinal materials are made into finer powders, the surface area is increased, which is conducive to the dissolution and absorption of subsequent ingredients, and is placed in a traditional Chinese medicine jar for easy subsequent operation.

[0050] 4. The oral medicine suitable for women with menstrual disorders and its production process obtain the medicine powder B by processing ginger, thereby ensuring the purity and availability of ginger and adding corresponding efficacy to the formula.

[0051] 5. The oral medicine for treating irregular menstruation in women and its manufacturing process, wherein the medicine powder is evenly dispersed and formed into a suitable consistency by adding water, mixing and stirring, and the addition of a disintegrant and a binder is helpful for the pill forming and disintegration and absorption in the body. DETAILED DESCRIPTION

[0052] The present invention will be further described in detail below in conjunction with specific embodiments. The embodiments of the present invention are provided for the purpose of illustration and description, and are not intended to be exhaustive or to limit the present invention to the disclosed forms. Many modifications and variations will be apparent to those of ordinary skill in the art. The embodiments are selected and described to better illustrate the principles and practical applications of the present invention, and to enable those of ordinary skill in the art to understand the present invention and thereby design various embodiments with various modifications suitable for specific uses.

[0053] In the first embodiment, the present invention provides a technical solution: an oral medicament suitable for treating menstrual disorders in women, comprising the following materials: 6 parts by mass of bupleurum, 12 parts by mass of white peony root, 12 parts by mass of atractylodes, 12 parts by mass of Poria, 5 parts by mass of licorice, 5 parts by mass of mint, 12 parts by mass of Codonopsis pilosula, 12 parts by mass of Leonurus japonicus, 8 parts by mass of peach kernel, 8 parts by mass of safflower, 12 parts by mass of Rehmannia glutinosa, 8 parts by mass of Cyperus rotundus, 8 parts by mass of Artemisia argyi, 8 parts by mass of red dates, 12 parts by mass of Angelica sinensis, 9 parts by mass of ginger, 4 parts by mass of a disintegrant and 4 parts by mass of a binder.

[0054] The disintegrant is composed of microcrystalline cellulose, cross-linked polyvinyl pyrrolidone and sodium carboxymethyl starch; the binder is composed of alginate, gelatin and sodium carboxymethyl cellulose.

[0055] A process for preparing an oral medicament for treating irregular menstruation in women, comprising the following steps:

[0056] Step 1: Weigh the herbs such as Bupleurum, White Peony Root, Atractylodes Macrocephala, Poria, Licorice, Mint, Codonopsis, Leonurus, Peach Kernel, Safflower, Rehmannia Glutinosa, Cyperus Rhizoma, Artemisia selengensis, and Red Dates according to the formula ratio, and select the herbs by air. The steps of air selection are as follows:

[0057] A1. The Chinese medicinal materials to be air-selected are fed into the air-selection chamber through the feeding mechanism;

[0058] A2. The electrostatic generator generates an electrostatic field;

[0059] A3. Under the combined action of airflow and electrostatic field, the Chinese medicinal materials are air-selected to separate impurities;

[0060] Then, impurities and non-medicinal parts are removed and mixed to obtain mixed medicinal material A;

[0061] Step 2: Put the mixed medicinal material A into a traditional Chinese medicine grinder and crush it, and sieve the crushed medicinal material powder. The sieving is specifically ultrasonic-assisted sieving. The ultrasonic frequency of the ultrasonic-assisted sieving is 20 kHz, the ultrasonic sieving time is 5 minutes, and the sieving mesh number is 70 to obtain mixed medicinal powder A, and put the mixed medicinal powder A into a traditional Chinese medicine tank.

[0062] Step 3: Select ginger that has not deteriorated, wash the impurities on the surface of the ginger with clean water, and then dry and crush the processed ginger. The specific steps for drying and crushing ginger are as follows:

[0063] S1. Cut ginger into small pieces, and then evenly spread the cut ginger pieces in a dryer for drying, turning the small pieces of ginger over every ten minutes during the drying process;

[0064] S2, placing the dried ginger pieces on a tray to cool to room temperature for later use;

[0065] S3, putting the cooled dried ginger pieces into a traditional Chinese medicine grinder for grinding, and sieving the ground ginger powder to obtain medicine powder B;

[0066] Step 4: Put the mixed powder A into a mixing tank, gradually add 1.2 times the amount of water during the mixing and stirring process, divide the 1.2 times the amount of water into four parts, add one part of water to the mixing tank every 5 minutes, and the stirring and mixing time of the mixing tank is 1.5 hours. After mixing and stirring for 30 minutes, add the disintegrant and the binder to the mixing tank to obtain a thick paste;

[0067] Step 5: Wash and dry the surface of the mint, and crush the mint in a traditional Chinese medicine grinder for 20 minutes to obtain mint powder, which is then dried for later use;

[0068] Step 6: Heat the thick paste in a heating tank for 1.5 hours at a temperature of 70 degrees Celsius, add mint powder, stir and mix, then take out the mixture and put it into a storage tank;

[0069] Step 7: Dry the mixture in the storage tank and knead it into pills of uniform size through a pill rolling board. The prepared pills are placed on a drying tray and put into a drying oven for drying to obtain finished pills.

[0070] The second embodiment, on the basis of the first embodiment, is an oral medicament suitable for treating menstrual disorders in women, comprising the following materials: 10 parts by mass of bupleurum, 15 parts by mass of white peony root, 15 parts by mass of atractylodes, 15 parts by mass of poria, 6 parts by mass of licorice, 6 parts by mass of mint, 15 parts by mass of codonopsis, 15 parts by mass of motherwort, 10 parts by mass of peach kernel, 10 parts by mass of safflower, 15 parts by mass of prepared rehmannia, 10 parts by mass of cyperus, 10 parts by mass of wormwood, 10 parts by mass of red dates, 15 parts by mass of angelica, 10 parts by mass of ginger, 10 parts by mass of a disintegrant and 10 parts by mass of a binder.

[0071] The disintegrant is composed of microcrystalline cellulose, cross-linked polyvinyl pyrrolidone and sodium carboxymethyl starch; the binder is composed of alginate, gelatin and sodium carboxymethyl cellulose.

[0072] A process for preparing an oral medicament for treating irregular menstruation in women, comprising the following steps:

[0073] Step 1: Weigh the herbs such as Bupleurum, White Peony Root, Atractylodes Macrocephala, Poria, Licorice, Mint, Codonopsis, Leonurus, Peach Kernel, Safflower, Rehmannia Glutinosa, Cyperus Rhizoma, Artemisia selengensis, and Red Dates according to the formula ratio, and select the herbs by air. The steps of air selection are as follows:

[0074] A1. The Chinese medicinal materials to be air-selected are fed into the air-selection chamber through the feeding mechanism;

[0075] A2. The electrostatic generator generates an electrostatic field;

[0076] A3. Under the combined action of airflow and electrostatic field, the Chinese medicinal materials are air-selected to separate impurities;

[0077] Then, impurities and non-medicinal parts are removed and mixed to obtain mixed medicinal material A;

[0078] Step 2: Put the mixed medicinal material A into a traditional Chinese medicine grinder and crush it, and sieve the crushed medicinal material powder. The sieving is specifically ultrasonic-assisted sieving. The ultrasonic frequency of the ultrasonic-assisted sieving is 40 kHz, the ultrasonic sieving time is 15 minutes, and the sieving mesh number is 90 meshes to obtain mixed medicinal powder A, and put the mixed medicinal powder A into a traditional Chinese medicine tank.

[0079] Step 3: Select ginger that has not deteriorated, wash the impurities on the surface of the ginger with clean water, and then dry and crush the processed ginger. The specific steps for drying and crushing ginger are as follows:

[0080] S1. Cut ginger into small pieces, and then evenly spread the cut ginger pieces in a dryer for drying, turning the small pieces of ginger over every ten minutes during the drying process;

[0081] S2, placing the dried ginger pieces on a tray to cool to room temperature for later use;

[0082] S3, putting the cooled dried ginger pieces into a traditional Chinese medicine grinder for grinding, and sieving the ground ginger powder to obtain medicine powder B;

[0083] Step 4: Put the mixed powder A into a mixing tank, gradually add 1.6 times the amount of water during the mixing and stirring process, divide the 1.6 times the amount of water into four parts, add one part of the water to the mixing tank every 5 minutes, and the stirring and mixing time of the mixing tank is 2 hours. After mixing and stirring for 30 minutes, add the disintegrant and the binder to the mixing tank to obtain a thick paste;

[0084] Step 5: Wash and dry the surface of the mint, and crush the mint in a traditional Chinese medicine grinder for 20 minutes to obtain mint powder, which is then dried for later use;

[0085] Step 6: Heat the thick paste in a heating tank for 2 hours at a temperature of 60 degrees Celsius, add mint powder, stir and mix, then take out the mixture and put it into a storage tank;

[0086] Step 7: Dry the mixture in the storage tank and knead it into pills of uniform size through a pill rolling board. The prepared pills are placed on a drying tray and put into a drying oven for drying to obtain finished pills.

[0087] The third embodiment, on the basis of the first and second embodiments, is an oral medicament suitable for treating menstrual disorders in women, comprising the following materials: 3 parts by mass of bupleurum, 10 parts by mass of white peony root, 10 parts by mass of atractylodes, 10 parts by mass of poria, 3 parts by mass of licorice, 3 parts by mass of mint, 10 parts by mass of codonopsis, 10 parts by mass of motherwort, 6 parts by mass of peach kernel, 6 parts by mass of safflower, 10 parts by mass of rehmannia glutinosa, 6 parts by mass of cyperus, 3 parts by mass of wormwood, 3 parts by mass of red dates, 10 parts by mass of angelica, 3 parts by mass of ginger, 2 parts by mass of a disintegrant and 2 parts by mass of a binder.

[0088] The disintegrant is composed of microcrystalline cellulose, cross-linked polyvinyl pyrrolidone and sodium carboxymethyl starch; the binder is composed of alginate, gelatin and sodium carboxymethyl cellulose.

[0089] A process for preparing an oral medicament for treating irregular menstruation in women, comprising the following steps:

[0090] Step 1: Weigh the herbs such as Bupleurum, White Peony Root, Atractylodes Macrocephala, Poria, Licorice, Mint, Codonopsis, Leonurus, Peach Kernel, Safflower, Rehmannia Glutinosa, Cyperus Rhizoma, Artemisia selengensis, and Red Dates according to the formula ratio, and select the herbs by air. The steps of air selection are as follows:

[0091] A1. The Chinese medicinal materials to be air-selected are fed into the air-selection chamber through the feeding mechanism;

[0092] A2. The electrostatic generator generates an electrostatic field;

[0093] A3. Under the combined action of airflow and electrostatic field, the Chinese medicinal materials are air-selected to separate impurities;

[0094] Then, impurities and non-medicinal parts are removed and mixed to obtain mixed medicinal material A;

[0095] Step 2: Put the mixed medicinal material A into a traditional Chinese medicine grinder and crush it, and sieve the crushed medicinal material powder. The sieving is specifically ultrasonic-assisted sieving. The ultrasonic frequency of the ultrasonic-assisted sieving is 20 kHz, the ultrasonic sieving time is 5 minutes, and the sieving mesh number is 70 to obtain mixed medicinal powder A, and put the mixed medicinal powder A into a traditional Chinese medicine tank.

[0096] Step 3: Select ginger that has not deteriorated, wash the impurities on the surface of the ginger with clean water, and then dry and crush the processed ginger. The specific steps for drying and crushing ginger are as follows:

[0097] S1. Cut ginger into small pieces, and then evenly spread the cut ginger pieces in a dryer for drying, turning the small pieces of ginger over every ten minutes during the drying process;

[0098] S2, placing the dried ginger pieces on a tray to cool to room temperature for later use;

[0099] S3, putting the cooled dried ginger pieces into a traditional Chinese medicine grinder for grinding, and sieving the ground ginger powder to obtain medicine powder B;

[0100] Step 4: Put the mixed powder A into a mixing tank, gradually add 1.2 times the amount of water during the mixing and stirring process, divide the 1.2 times the amount of water into four parts, add one part of water to the mixing tank every 5 minutes, and the stirring and mixing time of the mixing tank is 1.5 hours. After mixing and stirring for 30 minutes, add the disintegrant and the binder to the mixing tank to obtain a thick paste;

[0101] Step 5: Wash and dry the surface of the mint, and crush the mint in a traditional Chinese medicine grinder for 20 minutes to obtain mint powder, which is then dried for later use;

[0102] Step 6: Heat the thick paste in a heating tank for 1 hour at a temperature of 60 degrees Celsius, add mint powder into the tank, stir and mix, then take out the mixture and put it into a storage tank;

[0103] Step 7: Dry the mixture in the storage tank and knead it into pills of uniform size through a pill rolling board. The prepared pills are placed on a drying tray and put into a drying oven for drying to obtain finished pills.

[0104] Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field and related fields without creative work should fall within the scope of protection of the present invention. The structures, devices and operating methods not specifically described and explained in the present invention are implemented according to the conventional means in the field unless otherwise specified and limited.

Claims

1. An oral medicament suitable for treating irregular menstruation in women, characterized in that: The composition comprises the following materials: 3-10 parts by mass of bupleurum, 10-15 parts by mass of white peony root, 10-15 parts by mass of atractylodes, 10-15 parts by mass of poria, 3-6 parts by mass of licorice, 3-6 parts by mass of mint, 10-15 parts by mass of codonopsis pilosula, 10-15 parts by mass of motherwort, 6-10 parts by mass of peach kernel, 6-10 parts by mass of safflower, 10-15 parts by mass of rehmannia glutinosa, 6-10 parts by mass of cyperus rotundus, 3-10 parts by mass of wormwood, 3-10 parts by mass of red dates, 10-15 parts by mass of angelica, 3-10 parts by mass of ginger, 2-10 parts by mass of disintegrant and 2-10 parts by mass of binder.

2. The oral medicament for treating menstrual disorders in women according to claim 1, characterized in that: The composition is composed of the following materials: 6 parts by mass of bupleurum, 12 parts by mass of white peony root, 12 parts by mass of atractylodes, 12 parts by mass of poria, 5 parts by mass of licorice, 5 parts by mass of mint, 12 parts by mass of codonopsis, 12 parts by mass of motherwort, 8 parts by mass of peach kernel, 8 parts by mass of safflower, 12 parts by mass of rehmannia prepared, 8 parts by mass of cyperus, 8 parts by mass of wormwood, 8 parts by mass of red dates, 12 parts by mass of angelica, 9 parts by mass of ginger, 4 parts by mass of disintegrant and 4 parts by mass of binder.

3. The oral medicament for treating menstrual disorders in women according to claim 2, characterized in that: The disintegrant consists of microcrystalline cellulose, cross-linked polyvinyl pyrrolidone and sodium carboxymethyl starch; and the binder consists of alginate, gelatin and sodium carboxymethyl cellulose.

4. The process for preparing an oral medicament for treating irregular menstruation in women according to claim 3, characterized in that: It consists of the following steps: Step 1, weighing the medicinal materials such as bupleurum, white peony root, atractylodes, tuckahoe, liquorice, mint, codonopsis, motherwort, peach kernel, safflower, prepared rehmannia, cyperus, wormwood, red dates according to the formula ratio, and air-selecting the medicinal materials to remove impurities and non-medicinal parts, and mixing them to obtain mixed medicinal materials A; Step 2: Put the mixed medicinal material A into a traditional Chinese medicine grinder for crushing, and sieve the crushed medicinal material powder to obtain mixed medicinal powder A, and put the mixed medicinal powder A into a traditional Chinese medicine tank; Step 3: Select ginger that has not deteriorated, wash the impurities on the surface of the ginger with clean water, and then dry and crush the processed ginger to obtain powder B; Step 4: Place the mixed powder A into a mixing tank, gradually add 1.2-1.6 times the amount of water during the mixing and stirring process, and add the disintegrant and binder into the mixing tank after mixing and stirring for 30 minutes to obtain a thick paste; Step 5: Wash and dry the surface of the mint, and grind the mint in a traditional Chinese medicine grinder to obtain mint powder, which is then dried for later use; Step 6: Heat the thick paste in a heating tank, add mint powder into it, stir and mix, then take out the mixture and put it into a storage tank; Step 7: Dry the mixture in the storage tank and knead it into pills of uniform size through a pill rolling board. The prepared pills are placed on a drying tray and put into a drying oven for drying to obtain finished pills.

5. The process for preparing an oral medicament for treating irregular menstruation in women according to claim 4, characterized in that: The steps of wind selection of Chinese medicinal materials in step 1 are as follows: A1. The Chinese medicinal materials to be air-selected are fed into the air-selection chamber through the feeding mechanism; A2. The electrostatic generator generates an electrostatic field; A3. Under the combined action of airflow and electrostatic field, Chinese medicinal materials are air-selected to separate impurities.

6. The process for preparing an oral medicament for treating irregular menstruation in women according to claim 4, characterized in that: The screening in step 2 is specifically ultrasonic assisted screening, the ultrasonic frequency of the ultrasonic assisted screening is 20-40kHz, the ultrasonic screening time is 5-15 minutes, and the mesh size of the screening is 70-90 mesh.

7. The process for preparing an oral medicament for treating menstrual disorders in women according to claim 4, characterized in that: The specific drying and crushing operation steps of ginger in step 3 are: S1. Cut ginger into small pieces, and then evenly spread the cut ginger pieces in a dryer for drying, turning the small pieces of ginger over every ten minutes during the drying process; S2, placing the dried ginger pieces on a tray to cool to room temperature for later use; S3, putting the cooled dry ginger pieces into a traditional Chinese medicine grinder for grinding, and sieving the ground ginger powder.

8. The process for preparing an oral medicament for treating menstrual disorders in women according to claim 4, characterized in that: In the step 4, 1.2-1.6 times the amount of water is divided into four parts, and one part of the water is added to the stirring tank every 5 minutes. The stirring and mixing time of the stirring tank is 1.5-2 hours.

9. The process for preparing an oral medicament for treating menstrual disorders according to claim 4, characterized in that: In the step 5, the mint is put into the traditional Chinese medicine grinder for 20-30 minutes.

10. The process for preparing an oral medicament for treating irregular menstruation in women according to claim 4, characterized in that: In step 6, the thick paste is placed in a heating tank and heated for 1-2 hours at a temperature of 60-70 degrees Celsius.