Micro-infusion device for brain

Abstract

The invention provides a brain micro-infusion device which comprises a filter, an extension tube, a filter connecting device, a tube cavity fixing device, a skull fixing component and a brain infusion puncture assembly, one end of the extension tube is connected with the filter, the filter connecting device is connected with the other end of the extension tube, and the filter connecting device is connected with the other end of the extension tube. The filter device is connected with the brain infusion puncture assembly, the lumen fixing device is connected with the filter device, the skull fixing component is connected with the lumen fixing device, and the brain infusion puncture assembly is connected with the filter connecting device, the lumen fixing device and the skull fixing component into a whole. The brain micro-drug infusion system not only solves the problem that no brain micro-drug infusion system exists clinically at present, but also has the advantages of being accurate and controllable in infusion drug amount, free of liquid leakage and free of exosmosis in the whole pipeline, and meanwhile solves the problem that multi-target injection in the brain is difficult to implement clinically.

Description

Technical Field

[0001] The present invention relates to the field of medical devices, in particular to a brain micro-infusion device. Background Art

[0002] With the development and application of gene therapy, cell therapy and molecular biological drug therapy for neurological diseases, more and more refractory neurological diseases require precise drug infusion to the target tissue in the patient's brain with the assistance of a framed brain stereotactic instrument or frameless neuronavigation or surgical robot. Therefore, a brain micro-infusion drug system used in conjunction with a brain stereotactic instrument or frameless neuronavigation system or surgical robot is clinically needed. At present, gene therapy, cell therapy and molecular biological drug therapy for the treatment of neurological diseases with the help of brain target drug injection are mainly concentrated in preclinical research, and widespread clinical application is just around the corner. However, there is still a lack of safe and convenient brain micro-drug infusion systems in clinical practice.

[0003] Existing drug injection systems are mainly used in animal brain experimental research. The equipment is rough and cannot be used in the human brain. A small number of drug injections used in human brain research are performed through "piecemeal" instruments. The structure is complicated and the pipeline is frequently disassembled during the fixing process. It is easy to cause gas in the drug infusion pipeline, resulting in inaccurate injection volume. Frequent disassembly during the fixing process of the infusion pipeline leads to drug leakage and loss of liquid medicine. It is also easy to cause contamination and damage to surgical instruments or brain surgical areas. At the same time, it is difficult to implement multi-target injections in the brain, and effective treatment cannot be performed, which is difficult to meet clinical use. The present invention provides a brain micro-infusion device to solve the above problems. Summary of the invention

[0004] In view of the shortcomings of the prior art, the purpose of the present invention is to provide a brain micro-infusion device to solve the problems raised in the above-mentioned background technology. The present invention has the advantages of precise controllable amount of infused drugs, no leakage in the entire pipeline, and no extravasation.

[0005] In order to achieve the above-mentioned purpose, the present invention is implemented through the following technical scheme: a brain micro-infusion device includes a filter, an extension tube, a filter connecting device, a lumen fixing device, a skull fixing component and a brain infusion puncture assembly, one end of the extension tube is connected to the filter, the filter connecting device is connected to the other end of the extension tube, the lumen fixing device is connected to the filter device, the skull fixing component is connected to the lumen fixing device, and the brain infusion puncture assembly is respectively connected to the filter connecting device, the lumen fixing device and the skull fixing component as a whole.

[0006] In a brain micro-infusion device provided by the present invention, the brain infusion puncture assembly includes a drainage tube body, a hollow support tube, an outer hose, a puncture head and a support tube fixing cover, the support tube fixing cover is connected to the hollow support tube, the drainage tube body is located inside the hollow support tube, the hollow support tube is located inside the outer hose, and one end of the drainage tube body away from the skull fixing component and one end of the outer hose away from the skull fixing component form the puncture head.

[0007] In a brain micro-infusion device provided by the present invention, the filter connecting device includes a contraction nut, a contraction bracket and a drainage tube contraction body, wherein the contraction nut is sleeved on the outside of the contraction bracket and is used to fix the outside of the contraction bracket, the contraction bracket is sleeved on the outside of the drainage tube contraction body, and the contraction bracket and the drainage tube contraction body have concentric through holes, and the through holes are used to accommodate the drainage tube body to pass through.

[0008] In a brain micro-infusion device provided by the present invention, the lumen fixing device comprises a base and a fixing cover, the base is located inside the fixing cover, and the fixing cover is connected to the skull fixing component.

[0009] In a brain micro-infusion device provided by the present invention, the filter connecting device is a detachable structure for connecting to the filter.

[0010] In a brain micro-infusion device provided by the present invention, a third opening is provided at one end of the hollow support tube close to the support tube fixing cover, and the third opening is used to accommodate the drainage tube body to pass through.

[0011] In a brain microinfusion device provided by the present invention, a first opening, a first groove and a second groove are provided inside the base, the first groove is provided on one side of the base, the second groove is located on the other side of the base, and the first opening is used to fix the drainage tube body.

[0012] The brain micro-infusion device provided by the present invention further includes a hook connected to the second groove.

[0013] In a brain micro-infusion device provided by the present invention, a thread is formed at one end of the skull fixing component away from the tubular cavity component for connecting the skull fixing component to the skull of a patient.

[0014] In a brain micro-infusion device provided by the present invention, a second opening is provided on one side of the fixed cover to prevent the drainage tube from shifting.

[0015] Beneficial effects of the present invention:

[0016] 1. The brain micro-infusion device provided by the present invention can be firmly fixed on the patient's skull through the synergistic effect of the lumen fixing device and the skull fixing component, reducing the risk of the system moving or falling off during use, thereby ensuring the accuracy and safety of the infusion. The brain infusion puncture component is connected to the filter connecting device, the lumen fixing device, and the skull fixing component as a whole. This integrated design simplifies the operation process, reduces the difficulty and time cost of operation, improves work efficiency, and enhances the treatment effect.

[0017] 2. The present invention can effectively remove impurities and particles in the medicine by configuring the filter and the filter connecting device, ensuring that the medicine will not leak or be contaminated by the outside during the infusion process.

[0018] 3. The present invention can also realize simultaneous injection of multiple targets in the same side of the brain and injection of multiple targets in bilateral brains according to clinical needs through the precise coordination of the skull fixation component and the lumen fixation device. It is easy to use, saves drug infusion time, shortens clinical anesthesia time, and is conducive to the rapid recovery of patients after anesthesia.

[0019] 4. The present invention designs a hollow support tube with a side opening, which can effectively avoid the problem of the drainage tube being blocked and unable to infuse drugs after being fixed. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 An exploded schematic diagram of a skull fixation device provided in an embodiment of the present application;

[0021] Figure 2 A partially enlarged view of a skull fixation device provided in an embodiment of the present application;

[0022] Figure 3 An external view of a skull fixation device provided in an embodiment of the present application;

[0023] Figure 4 This is an external structural diagram of a brain microinfusion device for this application;

[0024] Figure 5 This is a three-dimensional schematic diagram of a hollow support tube of a brain microinfusion device of the present application in an implanted state;

[0025] Figure 6 This is a schematic diagram of an explosion of a hollow support tube structure of a brain microinfusion device of the present application;

[0026] Figure 7 This is a three-dimensional schematic diagram of the side hole support tube of a brain micro-infusion device of the present application in the inserted state;

[0027] Figure 8This is an exploded schematic diagram of a side hole support tube structure of a brain microinfusion device of the present application;

[0028] 1. Lumen fixing device; 10. Base; 101. First opening; 102. First groove; 103. Second groove; 11. Fixing cover; 111. Second opening;

[0029] 2. Hook;

[0030] 3. skull fixing component; 30. third groove; 31. thread;

[0031] 4. Filter;

[0032] 5. Extension tube;

[0033] 6. Filter connecting device; 61. Contraction nut; 62. Contraction bracket; 63. Drainage tube contraction body;

[0034] 7. Brain infusion puncture assembly; 71. Drainage tube body; 72. Hollow support tube; 721. Third opening; 73. Outer hose; 74. Puncture head; 75. Support tube fixing cover; DETAILED DESCRIPTION

[0035] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0036] Example 1

[0037] The applicant has found that there is no skull fixation device for brain microdrug infusion tubes in the existing technology. Brain microdrug injection requires a stable fixation effect for the brain microdrug infusion tube to ensure that the infusion tube can be accurately positioned in the target brain area, thereby achieving precise injection. Therefore, a skull fixation device for brain microdrug infusion tubes is urgently needed clinically.

[0038] In view of this, in order to solve the above problems, the applicant has proposed a skull fixation device, see Figure 2 , Figure 2 This is a partially enlarged view of a skull fixation device provided in an embodiment of the present application. The skull fixation device of the brain microinfusion system includes: a base 10, a first opening 101, a first groove 102, a second groove 103 and a hook 2.

[0039] Among them, the base 10, the first opening 101 is arranged in the base 10, and a first groove 102 is arranged on one side of the base 10; the second groove 103 is located on the other side of the base 10, and the hook 2 is arranged inside the second groove 103, which is used to stably fix the drug infusion tube to ensure that the drug infusion tube will not move easily in the skull.

[0040] The above content also includes a skull fixing component 3, and the base 10 can be arranged inside the skull fixing component 3. The arrangement of the skull fixing component 3 not only enhances the stability of the entire device, but also ensures that the base 10 can fit tightly and accurately on the skull fixing component 3.

[0041] In addition, a fixing cover 11 may be included, which is connected to one end of the skull fixing component 3 having a third groove 30. The fixing cover 11 may also be connected to the skull fixing component 3 via a thread 31. The thread 31 connection design not only ensures that the fixing cover 11 can fit tightly on the skull fixing component 3, but also provides adjustable tightness so that the doctor can make fine adjustments according to surgical requirements.

[0042] At the same time, the close cooperation between the fixing cover 11 and the skull fixing component 3 further improves the stability and reliability of the entire device, providing a more stable and safe supporting environment for brain microinfusion operations, which not only simplifies the surgical operation process, but also improves the accuracy of the operation and the patient's rehabilitation effect.

[0043] Among them, one end of the skull fixing component 3 may be provided with a third groove 30 for accommodating the base 10, which can achieve a close connection between the base 10 and the skull fixing component 3, improve the stability of the entire device, simplify the installation process, and allow the doctor to complete the fixation of the device more quickly. In addition, the skull fixing component 3 may be internally a soft hollow tube, preferably made of silicone, for allowing the drug infusion tube to pass through without kinking.

[0044] See also Figure 3 , Figure 3 This is an external diagram of a skull fixation device provided in an embodiment of the present application. The other end of the skull fixation component 3 is provided with a circle of threads 31 for matching with the threaded holes 31 on the surface of the patient. By rotating the skull fixation component 3 so that its threads 31 are tightly combined with the threaded holes 31 on the patient's skull, any accidental loosening or displacement can be effectively prevented, ensuring that the skull fixation component 3 can be firmly fixed on the patient's skull. This design not only provides stable support for subsequent operations such as brain microinfusion, but also enhances the safety of the operation and the comfort of the patient.

[0045] In order to accommodate the drainage tube and ensure the continuity and stability of the infusion system, a second opening 111 can be provided on the fixed cover 11, so that the drainage tube can pass through the fixed cover 11 without hindrance, effectively preventing the drainage tube from shifting or falling off during the operation, thereby ensuring the stability of the entire infusion system.

[0046] At the same time, the surface of the fixed cover 11 is provided with an anti-slip texture, which increases the stability of the doctor when covering the fixed cover 11, ensures that the doctor can firmly grasp the fixed cover 11, and perform accurate and fast operations, thereby improving the safety of the operation and reducing misoperation caused by hand slippage, thereby improving the overall efficiency of the operation. The friction between the fixed cover 11 and the doctor's hand can be effectively increased, ensuring that the doctor can firmly hold the fixed cover 11 even if the hand is sweating or other lubricants are present during the operation.

[0047] In this embodiment, the skull fixation component 3 can be made of polymer materials or titanium alloys. Polymer materials are favored for their light weight, corrosion resistance, and good biocompatibility. It can effectively reduce the burden on patients, reduce postoperative rejection reactions, and promote faster recovery of patients. In addition, polymer materials also have good processing properties and can be customized into fixed components of various shapes and sizes according to actual needs to meet different surgical needs. Titanium alloys are another important choice for skull fixation components 3 with their excellent properties such as high strength, wear resistance, and corrosion resistance. The firmness of titanium alloys can ensure that the fixed components are stable and reliable during the operation and are not prone to deformation or damage. At the same time, its good biocompatibility also ensures the safety of patients after surgery.

[0048] Working principle: During use, we first use the positioning guide device, combined with high-precision image guidance technology, such as a frame brain stereotactic instrument, a neuronavigation system or an advanced surgical robot arm, to accurately determine the target position of the head. Then, we select an appropriate drilling kit to perform a detailed skull drilling operation, and then, the skull fixing component 3 with a thread 31 at one end is accurately placed on the patient's skull, and under the precise guidance of the positioning device, the skull fixing component 3 is firmly screwed onto the skull.

[0049] With the precise assistance of the positioning guide device and the stereotactic instrument or the surgical robot arm, we accurately send the brain microinjection catheter into the brain until the preset target position through the positioning guide device and the head skull fixation device. At this time, we put the base 10 into the third groove 30 of the skull fixation component 3, and place the injection catheter securely in the first opening 101. Then, by manually or using a holder to gently move the hook 2, it can smoothly enter the second groove 103, so as to tightly clamp the drug infusion tube to ensure that it is stable and motionless. Finally, we cover the fixing cover 11 to ensure that the brain microinjection catheter can pass through the second opening 111 smoothly, so as to effectively prevent the brain microinjection catheter from shifting during use and ensure the accuracy and safety of the operation.

[0050] Example 2

[0051] The embodiment of the present application also provides a brain micro-infusion system, including a skull fixation device, and a brain micro-infusion device in the above embodiment. The brain micro-infusion device cooperates with the skull fixation device to solve the dilemma that there is currently no brain micro-drug infusion system in clinical practice.

[0052] The inventors of the present application have found that the existing drug injection systems are mainly used in animal brain experimental research, and the equipment is crude and cannot be used in the human brain; a small number of drug injections used in human brain research are performed through "pieced together" instruments, which have cumbersome structures and frequent disassembly during the pipeline fixing process, which can easily cause gas to exist in the drug infusion pipeline and lead to inaccurate injection volume. Frequent disassembly during the infusion pipeline fixing process can cause drug leakage and loss of drug solution, and it is easy to cause contamination and damage to surgical instruments or brain surgical areas. At the same time, it is difficult to implement multi-target injections in the brain, and effective treatment cannot be carried out, which is difficult to meet clinical use. In view of this, the present application provides a brain micro-infusion device.

[0053] The brain micro-drug infusion device comprises a filter 4, an extension tube 5, a filter connecting device 6, a tube cavity fixing device 1, a skull fixing component 3 and a brain infusion puncture component 7.

[0054] Among them, one end of the extension tube 5 is connected to the filter 4, the filter connecting device 6 is connected to the other end of the extension tube 5, the lumen fixing device 1 is connected to the filter connecting device 6, the skull fixing component 3 is connected to the lumen fixing device 1, and the brain infusion puncture component 7 is respectively connected to the filter connecting device 6, the lumen fixing device 1, and the skull fixing component 3 as a whole.

[0055] In the above content, by setting the filter 4 and the filter connecting device 6, impurities and particles in the drug can be effectively removed, ensuring that the drug will not leak or be contaminated by the outside during the infusion process. In addition, by providing a thread 31 at the end of the skull fixing component 3 away from the base 10, the skull fixing component 3 can be connected to the patient's skull, ensuring that the system can be firmly fixed on the patient's skull, reducing the risk of the system moving or falling off during use, thereby ensuring the accuracy and safety of the infusion. And the brain infusion puncture component 7 is respectively connected to the filter connecting device 6, the tubular cavity fixing device 1, and the skull fixing component 3 as a whole. This integrated design simplifies the operation process and makes its structure simpler. The operation of drug infusion can be completed without disassembling the pipeline, saving time and cost, and improving work efficiency.

[0056] First, refer to Figure 8The brain infusion puncture assembly 7 is composed of a drainage tube body 71, a hollow support tube 72, an outer hose 73, a puncture head 74, and a support tube fixing cover 75, wherein the support tube fixing cover 75 is arranged on the upper part of the hollow support tube 72, the drainage tube body 71 is arranged inside the hollow support tube 72, and the hollow support tube 72 is arranged inside the outer hose 73. In terms of specific dimensions, the outer hose 73 can be 240-260 mm long, preferably 250 mm, and can be 2.0-5.0 mm in diameter; the drainage tube body 71 can be 500 mm long, and can be 0.2-0.5 mm in diameter. The end of the intracranial drainage tube body 71 away from the skull fixation component 3 and the end of the outer hose 73 away from the skull fixation component 3 form a puncture head 74. The diameter of this puncture head 74 transitions from large to small in a conical shape and can be made of polymer material or ceramic material. This design enables the puncture head 74 to maintain extremely high stability and accuracy during the puncture process, and can easily penetrate the brain tissue, providing a strong guarantee for the smooth insertion of the drainage tube body 71.

[0057] At the same time, the sharpness and firmness of the puncture head 74 can also greatly reduce the resistance during the puncture process, improve the puncture efficiency, and alleviate the patient's pain. Moreover, the conical shape of the puncture head 74 can prevent the infused drug liquid from flowing backward along the tip of the drainage catheter.

[0058] In order to prevent the drug from leaking or being contaminated by the outside during the infusion process, the present application also provides a filter 4 and a filter connecting device 6, wherein the filter connecting device 6 is composed of a shrinking nut 61, a shrinking bracket 62 and a drainage tube shrinking body 63. The shrinking nut 61 can be tightly sleeved on the outside of the shrinking bracket 62. By rotating the shrinking nut 61, the shrinking nut 61 can firmly fix the position of the shrinking bracket 62 to prevent the shrinking bracket 62 from loosening or displacement during the infusion process. The shrinking bracket 62 is sleeved on the outside of the drainage tube shrinking body 63, and both are designed with concentric through holes. The size of this through hole can accommodate the drainage tube body 71 to pass through, thereby ensuring the smoothness of the infusion channel.

[0059] The filter connection device 6 can be a detachable connection, which specifically includes: a groove or a thread 31 structure is provided on the drainage tube contraction body 63. When the filter connection device 6 needs to be connected to the extension tube 5, it is only necessary to align one end of the extension tube 5 with the corresponding groove or thread 31 position on the drainage tube contraction body 63, and then rotate or push the extension tube 5, so that the buckle or thread 31 structure at one end of the extension tube 5 and the groove or thread 31 on the drainage tube contraction body 63 can be engaged with each other, so that the filter connection device 6 and the extension tube 5 can be tightly connected. When it is necessary to disassemble the filter connection device 6 and the extension tube 5, it is only necessary to follow the opposite operation steps, that is, rotate or pull the unlocking mechanism, so that the two can be easily separated without the need for additional tools or complicated operations.

[0060] Furthermore, when drilling and fixing the skull, the position of the head target point is first determined by using a positioning guide device combined with an image-guided framed stereotaxic instrument or a neuronavigation system or a surgical robot arm, and the skull is drilled using a drilling kit to ensure the accuracy and safety of the drilling. The dura mater is electrocoagulated using an electrocoagulation needle, and the skull fixation component 3 is installed under the guidance of the positioning device. A thread 31 is provided at one end of the skull fixation component 3 away from the base 10, which is used to connect the skull fixation component 3 to the patient's skull, ensuring the stability and safety of the entire infusion system.

[0061] In addition, the lumen fixing device 1 may include a base 10 and a fixing cover 11, wherein the base 10 is located inside the fixing cover 11, and the fixing cover 11 is connected to the end of the skull fixing component 3 away from the puncture head 74, which can ensure the continuity and stability of the entire infusion system, and also enable the drainage tube body 71 to be accurately positioned at the preset target position, thereby greatly improving the accuracy and safety of the infusion. Moreover, a second opening 111 is provided on one side of the fixing cover 11 to prevent the drainage tube body 71 from shifting or falling off during use, and to maximize the stability of the drainage tube body 71.

[0062] At the same time, a first opening 101 can be provided inside the base 10, and the first opening 101 is located on the outside of the drainage tube body 71 near one end of the fixed cover 11. When the hook 2 is moved to clamp the drainage tube body 71, the hook 2 located at the first opening 101 will firmly clamp the drainage tube body 71, thereby further improving the stability of the drainage tube body 71.

[0063] In addition, an annular cavity can be formed between the drainage tube body 71 and the outer hose 73, which accommodates a retractable hollow support tube 72, which can be 300 mm in length and 1.5-4.5 mm in diameter, and can be made of polymer materials or ceramics. Its retractable design enables medical personnel to adjust the position and length of the support tube as needed to adapt to different surgical needs. A third opening 721 is provided at one end of the hollow support tube 72 close to the support tube fixing cover 75. The third opening 721 is used to accommodate the drainage tube body 71 passing through. The drainage tube body 71 can be separated from the hollow support tube 72 through the third opening 721. The design of the third opening 721 makes the operation simpler and faster, and medical personnel can quickly separate the drainage tube body 71 from the hollow support tube 72 through the third opening 721.

[0064] Its working principle: when in use, first use the positioning guide device, combined with the image-guided framed technology, such as a framed brain stereotactic instrument, a neuronavigation system or a surgical robot mechanical arm to accurately determine the target position of the head, and then use a professional drilling kit to drill a suitable hole in the skull. Then, the electrocoagulation needle passes through the dura mater, and the head skull fixation component 3 is installed under the guidance of the positioning device, and its stability is determined. Next, one end of the filter connecting device 6 is connected to the drainage tube body 71, and the other end is connected to the filter 4 with an extension tube 5. The distal end of the extension tube 5 is connected to the drug syringe to form a complete infusion system. In order to ensure the smoothness and sterility of the infusion system, a micropump is used to exhaust the air in the infusion pipeline system, and then, with the assistance of the positioning guide device and the stereotactic instrument or the surgical robot mechanical arm, the puncture head 74 is accurately passed through the positioning guide device and the head skull fixation component 3 into the brain to the target point. Tighten the skull fixation component 3, withdraw the hollow support tube 72, and take out the drainage tube body 71 from the third opening 721, and separate it from the outer hose 73. Finally, the base 10 is placed between the skull fixing component 3 and the fixing cover 11. After the skull fixing component 3 and the fixing cover 11 are connected, they are rotated clockwise to be fixed, and the brain microinjection system can infuse drugs into the brain.

[0065] Embodiment 3:

[0066] In the present invention, see also Figure 6 As shown, the hollow support tube 72 does not need to have the third opening 721, and the drainage catheter can also be separated. The specific method is:

[0067] An annular cavity may be formed between the drainage tube body 71 and the outer hose 73 , in which a retractable hollow support tube 72 may be accommodated. The tube may be 300 mm in length and 2 mm in diameter and may be made of polymer material or ceramic.

[0068] When in use, first utilize the positioning guide device, combine the framed technology of image guidance, such as framed brain stereotactic instrument, neuronavigation system or surgical robot mechanical arm to accurately determine the target position of the head, then use professional drilling kit to drill suitable holes on the skull. Then penetrate the dura mater through the electrocoagulation needle, install the head skull fixing component 3 under the guidance of the positioning device, and determine its stability. Next, one end of the filter connecting device 6 is connected to the drainage tube body 71, and the other end is connected to the filter 4 with an extension tube 5, and the distal end of the extension tube 5 is connected to the drug injector to form a complete infusion system. In order to ensure the smoothness and asepticity of the infusion system, a micro pump is used to discharge the air in the infusion pipeline system, and then, with the assistance of the positioning guide device and the stereotactic instrument or surgical robot mechanical arm, the puncture head 74 is accurately passed through the positioning guide device and the head skull fixing component 3 into the brain to the target point. Tighten the skull fixing component 3, and pull the hollow support tube 72 out directly from the annular cavity formed between the drainage tube body 71 and the outer hose 73. Finally, place the base 10 between the skull fixing component 3 and the fixing cover 11. After the skull fixing component 3 is connected to the fixing cover 11, rotate it clockwise to fix it, and the brain microinjection system can infuse drugs into the brain.

[0069] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It is obvious to those skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and the present invention can be implemented in other specific forms without departing from the spirit or basic features of the present invention. Therefore, no matter from which point of view, the embodiments should be regarded as exemplary and non-restrictive. The scope of the present invention is defined by the attached claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims are included in the present invention. Any figure mark in the claims should not be regarded as limiting the claims involved.

[0070] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.

Claims

1. A brain microinfusion device, characterized in that: include Filters; An extension tube, one end of which is connected to the filter; A filter connecting device, the filter connecting device being connected to the other end of the extension tube; a lumen fixing device, the lumen fixing device being connected to the filter connecting device; A skull fixing component connected to the lumen fixing device; A brain infusion puncture component is connected to the filter connecting device, the lumen fixing device and the skull fixing component as a whole.

2. A brain microinfusion device according to claim 1, characterized in that: The brain infusion puncture assembly includes a drainage tube body, a hollow support tube, an outer hose, a puncture head and a support tube fixing cover, the support tube fixing cover is connected to the hollow support tube, the drainage tube body is located inside the hollow support tube, the hollow support tube is located inside the outer hose, and one end of the drainage tube body away from the skull fixing component and one end of the outer hose away from the skull fixing component form the puncture head.

3. A brain microinfusion device according to claim 2, characterized in that: The filter connecting device includes a shrinkage nut, a shrinkage bracket and a drainage tube shrinkage body, wherein the shrinkage nut is sleeved on the outside of the shrinkage bracket and is used to fix the outside of the shrinkage bracket, the shrinkage bracket is sleeved on the outside of the drainage tube shrinkage body, and the shrinkage bracket and the drainage tube shrinkage body have concentric through holes, which are used to accommodate the drainage tube body to pass through.

4. A brain microinfusion device according to claim 2, characterized in that: The tube cavity fixing device comprises a base and a fixing cover, wherein the base is located inside the fixing cover, and the fixing cover is connected to the skull fixing component.

5. A brain microinfusion device according to claim 1, characterized in that: The filter connecting device is a detachable structure and is used to connect the filter.

6. A brain microinfusion device according to claim 2, characterized in that: A third opening is provided at one end of the hollow support tube close to the support tube fixing cover, and the third opening is used to accommodate the drainage tube body to pass through.

7. A brain microinfusion device according to claim 4, characterized in that: The base is provided with a first opening, a first groove and a second groove inside. The first groove is provided on one side of the base, and the second groove is located on the other side of the base. The first opening is used to fix the drainage tube body.

8. A brain microinfusion device according to claim 7, characterized in that: It also includes a hook, which is connected to the second groove.

9. A brain microinfusion device according to claim 4, characterized in that: A thread is provided at one end of the skull fixing component away from the base for connecting the skull fixing component to the skull of a patient.

10. A brain microinfusion device according to claim 4, characterized in that: A second opening is provided on one side of the fixing cover to prevent the drainage tube body from shifting.

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