Pesticide composition

Abstract

The invention belongs to the technical field of pesticides, and relates to a pesticide composition and application. Effective components of the pesticide composition comprise an active component A and an active component B, the active component A is a compound shown in a formula (I), the active component B is Isoflualanam or Cybenzoxasulfyl, and the mass ratio of the active component A to the active component B is (1: 45)-(27: 1). The composition has the advantages of synergism, resistance delay and the like, and is used for preventing and treating resistant pests.

Description

Technical Field

[0001] The invention belongs to the technical field of pesticides, and particularly relates to a pesticide composition. Background Art

[0002] Isoflualanam is an isoxazoline insecticide, an allosteric modulator of γ-aminobutyric acid (GABA) gated chloride channels, with a unique mechanism of action and no cross-resistance with other insecticides. Isoflualanam has stomach toxicity, contact killing and certain systemic effects, is highly fast-acting, and has an ovicidal effect. The chemical structure is as follows:

[0003]

[0004] Cybenzoxasulfyl (oxazolidinone) belongs to the benzothiophene class of insecticides and has a broad insecticide spectrum. The chemical structure is as follows:

[0005]

[0006] In the process of agricultural production, the control of various harmful insects mainly relies on the application of a large number of pesticides and insecticides. The large-scale, frequent and unreasonable use of pesticides and insecticides has led to the continuous enhancement of the resistance of harmful insects, which has caused more serious damage to crops and made prevention and control more difficult. By mixing the compound of formula (I) with two or more agents with different action mechanisms such as Isoflualanam and Cybenzoxasulfyl, it is possible to simultaneously control different pests, expand the control spectrum, improve the control effect of the agent, and reduce the generation of pest resistance. Summary of the invention

[0007] The purpose of the present invention is to provide a pesticide composition which has synergistic effect, reduces resistance and has low use cost.

[0008] To achieve the above object, the technical solution adopted by the present invention is: a pesticide composition comprising an active ingredient A and an active ingredient B, wherein the active ingredient A is a compound of formula (I) The active ingredient B is Isoflualanam or Cybenzoxasulfyl;

[0009] Furthermore, the mass ratio between the active ingredient A and the active ingredient B is 1:45 to 27:1.

[0010] Furthermore, the mass ratio of the compound of formula (I) to Isoflualanam is 1:35 to 27:1;

[0011] Furthermore, the mass ratio of the compound of formula (I) to Isoflualanam is 1:35 to 18:1 or any value between the above values;

[0012] Furthermore, the mass ratio of the compound of formula (I) to Isoflualanam is 1:35, 1:22, 1:8, 1:3, 3:1, 10:1, 18:1, 27:1;

[0013] Furthermore, the mass ratio of the compound of formula (I) to Isoflualanam is 1:35, 1:22, 1:8, 1:3, 3:1, 10:1, 18:1;

[0014] Furthermore, the mass ratio of the compound of formula (I) to Cybenzoxasulfyl is 1:45 to 25:1;

[0015] Furthermore, the mass ratio of the compound of formula (I) to Cybenzoxasulfyl is 1:30 to 25:1 or any value between the above values;

[0016] Furthermore, the mass ratio of the compound of formula (I) to Cybenzoxasulfyl is 1:45, 1:30, 1:20, 1:10, 2:9, 9:2, 12:1, 25:1;

[0017] Furthermore, the mass ratio of the compound of formula (I) to Cybenzoxasulfyl is 1:30, 1:20, 1:10, 2:9, 9:2, 12:1, 25:1;

[0018] Furthermore, based on the total mass of the pesticide composition being 100 wt%, the sum of the contents of the active ingredient A and the active ingredient B in the pesticide composition is 0.5% to 90%;

[0019] Furthermore, the sum of the contents of the active ingredient A and the active ingredient B in the pesticide composition is 1% to 85%;

[0020] Furthermore, the pesticide composition includes agriculturally acceptable auxiliary ingredients in addition to the active ingredients, and the auxiliary ingredients are selected from one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoamers, solvents, preservatives, stabilizers, synergists or carriers;

[0021] Furthermore, the acaricide composition further comprises an adjuvant, which is selected from one or more of a wetting agent, a dispersant, an emulsifier, a thickener, a disintegrant, an antifreeze agent, a defoaming agent, a solvent, a preservative, a stabilizer, a synergist and a carrier;

[0022] The wetting agent is selected from one or more of alkylbenzene sulfonate, alkylnaphthalene sulfonate, lignin sulfonate, sodium dodecyl sulfate, sodium dioctyl succinate sulfonate, alpha olefin sulfonate, alkylphenol polyoxyethylene ether, castor oil polyoxyethylene ether, alkylphenol ethoxylate, fatty alcohol ethoxylate, fatty alcohol polyoxyethylene ether sodium sulfate, silkworm feces, saponin powder, soapberry powder, SOPA, detergent, emulsifier 2000 series and wetting penetrant F; and / or

[0023] The dispersant is selected from one or more of lignin sulfonate, alkylnaphthalene sulfonate formaldehyde condensate, naphthalene sulfonate, tristyrylphenol ethoxylate phosphate, fatty alcohol ethoxylate, alkylphenol polyoxyethylene ether, alkylphenol polyoxyethylene ether methyl ether condensate sulfate, fatty amine polyoxyethylene ether, glycerol fatty acid ester polyoxyethylene ether, polycarboxylates, polyacrylic acid, phosphates, EO-PO block copolymers and EO-PO graft copolymers; and / or

[0024] The emulsifier is selected from one or more of calcium dodecylbenzene sulfonate, alkylphenol formaldehyde resin polyoxyethylene ether, phenylethylphenol polyoxyethylene polyoxypropylene ether, fatty alcohol ethylene oxide-propylene oxide copolymer, styrylphenol polyoxyethylene ether, castor oil polyoxyethylene ether and alkylphenol ether phosphate; and / or

[0025] The thickener is selected from one or more of xanthan gum, organobentonite, gum arabic, sodium alginate, magnesium aluminum silicate, carboxymethyl cellulose and white carbon black; and / or

[0026] The disintegrant is selected from one or more of sodium sulfate, ammonium sulfate, aluminum chloride, sodium chloride, ammonium chloride, bentonite, glucose, sucrose, starch, cellulose, urea, sodium carbonate, sodium bicarbonate, citric acid and tartaric acid; and / or

[0027] The antifreeze agent is selected from one or more of alcohols, alcohol ethers, chlorinated hydrocarbons and inorganic salts; and / or

[0028] The defoamer is selected from C 10 -C 20 Saturated fatty acid compounds, silicone oil, silicone compounds, C8-C 10 One or more of fatty alcohols; and / or

[0029] The solvent is selected from one or more of benzene, toluene, xylene, durene, methanol, ethanol, isopropanol, n-butanol, dimethyl sulfoxide, dimethylformamide, cyclohexanone, alkylene carbonate, diesel, solvent oil, vegetable oil, vegetable oil derivatives and water; and / or

[0030] The preservative is selected from one or more of propionic acid, sodium propionic acid, sorbic acid, sodium sorbic acid, potassium sorbic acid, benzoic acid, sodium benzoic acid, sodium p-hydroxybenzoic acid, methyl p-hydroxybenzoate, kasone and 1,2-benzisothiazolin-3-one; and / or

[0031] The stabilizer is selected from one or more of disodium hydrogen phosphate, oxalic acid, succinic acid, adipic acid, borax, 2,6-di-tert-butyl-p-cresol, triethanolamine oleate, epoxidized vegetable oil, kaolin, bentonite, attapulgite, white carbon black, talc, montmorillonite and starch; and / or

[0032] The synergist is selected from synergist phosphite, synergist ether; and / or

[0033] The carrier is selected from one or more of ammonium salts, ground natural minerals, ground artificial minerals, silicates, resins, waxes, solid fertilizers, water, organic solvents, mineral oils, vegetable oils and vegetable oil derivatives.

[0034] Furthermore, the pesticide composition can be prepared into a formulation form permitted in agriculture, and the formulation form is selected from a solid formulation and / or a liquid formulation;

[0035] Furthermore, the solid preparation includes powders, granules, pellets, tablets, strips, wettable powders, oil-dispersible powders, emulsion powders, water-dispersible granules, emulsion granules, water-dispersible tablets, soluble powders, soluble tablets or soluble granules;

[0036] Further, the liquid preparation includes a soluble solution, a soluble gel, an oil, a film-spreading oil, an emulsifiable concentrate, a latex, a dispersible liquid, an ointment, an aqueous emulsion, an oil emulsion, a microemulsion, a fat, a suspension, a microcapsule suspension, an oil suspension, a dispersible oil suspension, a suspoemulsion, a microcapsule suspension-suspension, a microcapsule suspension-water emulsion or a microcapsule suspension-suspoemulsion;

[0037] Furthermore, the solid preparation is selected from wettable powders and water dispersible granules; the liquid preparation is selected from emulsifiable concentrates, aqueous emulsions, microemulsions, suspensions, suspoemulsions, and dispersible oil suspensions;

[0038] Application of the pesticide composition of the present invention in preventing and controlling agricultural and forestry pests and sanitary pests;

[0039] The pesticide composition of the present invention can be used to control pests on fruit trees, vegetables, ornamental plants, tea, cotton, and cereal crops;

[0040] Furthermore, the agricultural and forestry pests and sanitary pests are Lepidoptera pests;

[0041] Further, the Lepidoptera pests include: Adoxophyes spp., Adoxophyes orana, Agrotis spp. (cutworms), Agrotis ipsilon (black cutworm), Alabamaargillacea (cotton leafworm), Amorbia cuneana, Amyelosis transitella (navel orangeworm), Anacamptodes defectaria, Anarsia lineatella (peach twig borer), Anomis sabulifera (jute looper), Anticarsia g emma talis, Archips argyrospila (fruit tree leaf roller), Archips rose leaf roller, and A. rosana(rose leaf roller), Argyrotaenia spp.(tortricid moths), Argyrotaenia citrana(orange tortrix), Autographa gamma, Bonagota cranaodes, Borbo cinnara(rice leaf folder), Bucculatrix thurberiella(cotton leaf perforator), Caloptilia spp.(leaf miners), Capua reticulana, Carposina niponensis(peach fruit moth), Chilo spp., Chlumetia transversa(mango shoot borer), Choristoneura rosaceana(obliquebanded leaf roller), leafroller)), Chrysodeixis spp.), Cnaphalocerus medinalis (grass leafroller), Colias spp., Conpomorpha cramerella, Cossus cossus (carpenter moth), Crambus spp. (sod webworms), Cydia funebrana (plum fruit moth), Cydia molesta (oriental fruit moth), Cydia nignicana (pea moth), Cydia pomonella (codling moth), Darna diducta, Diaphania spp. (stem borer), borers), Diatraea spp. (stalk borers), Diatraea saccharalis (sugarcane borer), Diatraea graniosella (southwester corn borer), Earias spp.) (cotton bollworm), Earias insulata (Egyptian bollworm), Earias vitella (rough northern bollworm), Ecdytopopha aurantianum, Elasmopalpus lignosellus (lesser cornstalk borer), Epiphysias postruttana (light brown apple moth), Ephestia spp. (flour moths), Ephestia cautella (almond moth), Ephestia elutella (tobbacomoth), Ephestia kuehniella (Mediterranean flour moth), Epimeces spp., Epinotia aporema), Erionotathrax (banana skipper), Eupoecilia ambiguella (grapeberry moth), Euxoa auxiliaris (army cutworm), Feltia spp. (cutworms), Gortyna spp. (stemblerers), Grapholitamolesta (Oriental fruit moth).

[0042] The following are the main species of insects: oriental fruit moth, Hedylepta indicate (beanleaf webber), Helicoverpa sp p. (snodus), Helicoverpa armigera, Helicoverpa zea, Heliothis spp., Heliothis virescens, Hellula undalis (cabbage webworm), Indarbela spp. (root borers), Keiferia lycopersicella, Leucinodes orbonalis, Leucoptera malifoliella, Lithocollectis spp., Lobesia botrana (grape fruit moth). fruitmoth), Loxagrotis spp., Loxagrotis albicosta (western bean cutworm), Lymantria dispar (gypsy moth), Lyonetia clerkella (apple leaf miner), Mahasena corbetti (oil palm bagworm), Malacosoma spp.)(tent caterpillars), Mamestra brassicae(cabbage armyworm), Maruca testulalis(bean pod borer), Metisa plana, Mythimna unipuncta(true armyworm), Neoleucinodes elegantalis, Nymphula depunctalis, Operophtherabrumata, Ostrinia nubilalis(European corn borer), Oxydia vesulia, Pandemis cerasana(common currant tortrix), Pandemis heparana(brown apple tortrix), Papilio demodocus, Pectinophora gossypiella(pink bellworm), (bottomworm), Peridroma spp. (cutworm), Peridroma saucia (variegated cutworm), Perileucoptera coffeella (white coffee leafminer), Phthorimaea operculella (potato tuber moth), Phyllocnisitis citrella, Phyllonorycter spp., Pieris rapae, Plathypena scabra, Plodia interpunctella, Plutellaxylostella (diamondback moth), Polychrosis viteana (grapeberry moth), Prays endocarpa, Prays olive moth oleae) (olive moth), Pseudaletia spp.) (spotworm), Spodoptera litura Fabricius, Pseudaletia unipunctata (armyworm), Pseudoplusia includes (, Rachiplusia nu, Chilo suppressalis (Walker), Scirpophaga incertulas, Sesamia spp. (stem borers), Sesamia inferens (pink rice stem borer), Sesamia nonagrioides, Setora nitens, Sitotroga cerealella (Angoumois grain moth), Sparganothis pilleriana, Spodoptera spp., Spodoptera exigua, Spodoptera fugiperda), Spodoptera oridania (southern armyworm), Synanthedon spp., Thecla basilides, Thermisia gemmatalis, Tineola bisselliella (webbing clothes moth), Trichoplusia ni (pieris rapae), Pieris rapae Linne (pieris rapae), Tuta absoluta;

[0043] Furthermore, the lepidopteran pests include Plutella xylostella, Spodoptera exigua, Spodoptera litura, Chilo suppressalis, Cotton bollworm, and Pieris rapae;

[0044] Furthermore, the lepidopteran pest is Spodoptera litura.

[0045] The present invention also provides a method for using the above pesticide composition, which is to apply an effective dose to the pests to be controlled or the medium in which they grow.

[0046] The pesticide composition of the present invention has the following advantages:

[0047] 1) The pesticide composition of the present invention exhibits a synergistic effect within a certain ratio range, and has a significant control effect;

[0048] 2) The two active ingredients of the pesticide combination have a unique mechanism of action, are extremely effective against resistant pests, and can extend the service life of the product. DETAILED DESCRIPTION

[0049] The present invention is further described below with reference to the examples. The percentages in the examples are all percentages by weight, but the present invention is not limited thereto.

[0050] The composition of the present invention can be provided in the form of a preparation. It can be prepared into a suspension, water dispersible granules, aqueous emulsions, granules, wettable powders, dispersible oil suspensions, etc. as needed. The content of the active ingredient in the composition of the present invention depends on the application amount when used alone, and also depends on the mixing ratio and the degree of synergistic effect. The optimal range of the active ingredient content varies according to the type of preparation of the composition.

[0051] Preparation Example

[0052] Embodiment 1:

[0053] 5% compound of formula (I)·isoflualanam emulsifiable concentrate (1.5+3.5)

[0054] Formula: 1.5% compound of formula (I), 3.5% isoflualanam,

[0055] 4% propylene carbonate, 4% calcium dodecylbenzene sulfonate, 12% castor oil polyoxyethylene ether, 1% N,N-dimethylformamide, 2% corn oil, 30% cyclohexanone, and methyl oleate make up the balance;

[0056] Preparation method: firstly add the active ingredient into the solvent and completely dissolve it, then add the emulsifier and the like and stir evenly to form a uniform and transparent oily liquid, and then fill it to prepare the emulsifiable concentrate preparation of the composition of the present invention.

[0057] Embodiment 2:

[0058] 30% formula (Ⅰ) compound·isoflualanam suspension (5+25)

[0059] Formula: 5% compound of formula (I), 25% isoflualanam,

[0060] 3% fatty alcohol polyoxyethylene ether phosphate salt, 1% sodium lignin sulfonate, 3% alkyl aryl polyoxyethylene ether polyoxypropylene ether, 1% magnesium aluminum silicate, 0.2% xanthan gum, 0.5% methyl paraben, 4.5% ethylene glycol, 0.5% organosilicon defoamer, and deionized water to make up the balance;

[0061] Preparation method: Add active ingredients to the wetting dispersant and defoamer, use zirconium oxide beads, and use a sand mill to wet grind to D 90 (90% of the particle size) <10 μm, and a crushed slurry is obtained. A thickener, antifreeze agent, preservative, etc. are added to the crushed slurry and mixed evenly, and deionized water is added to 100%, and a suspension product is obtained by high-speed shearing.

[0062] Embodiment 3:

[0063] 48% Compound of formula (I)·isoflualanam water dispersible granules (8+40)

[0064] Formula: 8% compound of formula (I), 40% isoflualanam,

[0065] 6% sodium polycarboxylate, 2% sodium lignin sulfonate, 5% naphthalene sulfonate formaldehyde condensate, 3.5% sodium dodecyl sulfate, 4% sodium sulfate, 2% starch, and kaolin to make up the balance;

[0066] Preparation method: According to the formula ratio, the active ingredient is added to the carrier, and the surfactant and other functional additives are added thereto, mixed, and after air flow pulverization, appropriate water is added, and then the water-dispersible granule product is obtained by kneading, granulating, drying and sieving.

[0067] Embodiment 4:

[0068] 22% compound of formula (I)·cybenzoxasulfyl suspension (4+18)

[0069] Formula: 4% compound of formula (I), 18% cybenzoxasulfyl,

[0070] 3% fatty alcohol polyoxyethylene ether phosphate salt, 4% alkyl aryl polyoxyethylene ether polyoxypropylene ether, 1% naphthalene sulfonate formaldehyde condensate, 1% magnesium aluminum silicate, 0.2% xanthan gum, 0.5% methyl paraben, 5% propylene glycol, 0.5% silicone defoamer, and deionized water to make up the balance;

[0071] Preparation method: Same as Example 2.

[0072] Embodiment 5:

[0073] 16% compound of formula (I)·cybenzoxasulfyl dispersible oil suspension (3+13)

[0074] Formula: 3% compound of formula (I), 13% cybenzoxasulfyl,

[0075] 1.8% naphthalenesulfonate condensate, 12% castor oil polyoxyethylene ether, 3% fatty alcohol polyoxyethylene ether, 2% calcium dodecylbenzenesulfonate, 0.8% organic bentonite, and soybean oil to make up the balance;

[0076] Preparation method: According to the formula ratio, the active ingredients, surfactants and other functional additives are placed in the reactor in sequence, oil is added and mixed evenly, and the dispersible oil suspension product is obtained by high-speed shearing, wet sand grinding, and finally homogenization filtration.

[0077] Embodiment 6:

[0078] 20% compound of formula (Ⅰ)·cybenzoxasulfyl water dispersible granules (4+16)

[0079] Formula: 4% compound of formula (I), 16% cybenzoxasulfyl,

[0080] 5% sodium polycarboxylate, 2% sodium lignin sulfonate, 6% naphthalene sulfonate formaldehyde condensate, 2% sodium lauryl sulfate, 2% pull open powder BX, 2% starch, kaolin to make up the balance;

[0081] Preparation method: Same as Example 3.

[0082] Indoor biological activity assay

[0083] Refer to the agricultural industry standards "Guidelines for Indoor Bioassay Tests of Pesticides - Insecticides Part 6: Insect Dipping Method" (NY / T1154.6-2006), "Guidelines for Indoor Bioassay Tests of Pesticides - Insecticides Part 7: Determination of Combined Action of Mixtures" (NY / T1154.7-2006), "Guidelines for Indoor Bioassay Tests of Pesticides - Insecticides Part 14: Leaf Dipping Method" (NY / T 1154.14-2008), etc.

[0084] Specific indoor toxicity test:

[0085] Test target: Prodenia litura (Fabricius);

[0086] Test method: leaf dipping method combined with insect dipping method;

[0087] Drug preparation: The test drug was dissolved in acetone and prepared into 5 series of concentrations using 0.1% Tween 80 aqueous solution.

[0088] Test materials: Use a hole puncher to punch leaf discs (1.5 cm in diameter), immerse them in the drug solution for 10 seconds, wait for the solution to dry naturally, then place the cabbage pieces in a petri dish lined with moisturizing filter paper, place 20 3rd instar larvae in the drug solution for 5 seconds, absorb the excess drug solution with filter paper, and place the test insects in the petri dish with leaves immersed in the corresponding concentration;

[0089] Experimental treatment: Each treatment was repeated 4 times, and the blank treatment was used as the control. The treated test insects were placed in an artificial intelligence culture room at 25±1℃, light duration L:D=16h:8h, and relative humidity of 65%±5% for breeding.

[0090] Investigation method: Check the experimental results after 48 hours. Use the tip of a brush to touch the insect body. If there is no reaction, it is considered dead. Count the number of live and dead Spodoptera litura in each treatment and calculate the mortality rate.

[0091] Data statistics and analysis:

[0092] According to the survey data, the adjusted mortality rate of each treatment was calculated using the following formula, with the results retained to two decimal places:

[0093]

[0094] Where:

[0095] P——mortality rate, in percentage (%);

[0096] K——indicates the number of dead insects, in units of heads;

[0097] N——represents the total number of insects treated, in heads.

[0098]

[0099] Where:

[0100] P1——adjusted mortality rate, in percentage (%);

[0101] P t ——Treatment mortality rate, expressed as percentage (%);

[0102] P0——blank control mortality rate, in percentage (%).

[0103] If the control mortality rate is less than 5%, no correction is required; if the control mortality rate is between 5% and 20%, correction should be made according to formula (2); if the control mortality rate is greater than 20%, the test needs to be repeated.

[0104] The data can be processed by probability value analysis. The data statistical analysis system can be used to analyze the toxicity regression line, LC 50 The activity of the test agent on the biological test material was evaluated by using the value, 95% confidence limit and correlation coefficient r.

[0105] The co-toxicity coefficient (CTC value) of the mixture is calculated as follows:

[0106]

[0107] Where:

[0108] ATI——Actual Toxicity Index of Mixture;

[0109] S——LC of standard pesticide 50 , the unit is milligrams per liter (mg / L);

[0110] M——LC of the mixture 50 , the unit is milligrams per liter (mg / L).

[0111] TTI=TI A *P A +TI B *P B

[0112] Where:

[0113] TTI – Theoretical Toxicity Index of Mixtures;

[0114] TI A ——A: toxicity index of the agent;

[0115] P A ——The percentage of agent A in the mixture, in percentage (%);

[0116] TI B ——Toxicity index of agent B;

[0117] P B ——The percentage of agent B in the mixture, in percentage (%).

[0118]

[0119] Where:

[0120] CTC – Co-toxicity coefficient;

[0121] ATI——Actual Toxicity Index of Mixture;

[0122] TTI - Theoretical Toxicity Index of Mixture.

[0123] The co-toxicity coefficient of the combination CTC≥120 shows a synergistic effect; CTC≤80 shows an antagonistic effect; 80<CTC<120 shows an additive effect.

[0124] Test results:

[0125] Combined toxicity of mixed pairs to Spodoptera litura:

[0126] The LC of the compound of formula (I) against Spodoptera litura 50 The LC value of Isoflualanam against Spodoptera litura is 1.033 mg / L. 50The LC value of Cybenzoxasulfy to Spodoptera litura is 2.974 mg / L. 50 The compound of formula (I) mixed with Isoflualanam and Cybenzoxasulfy has a good combined effect on Spodoptera litura, and at a certain mass ratio, it shows obvious synergistic effect.

[0127] The results in Table 1 show that when the mass ratio of the compound of formula (I) to Isoflualanam is 1:35-27:1, the co-toxicity coefficient of the control effect on Spodoptera litura is greater than 80, showing an additive or synergistic effect; when the mass ratio of the compound of formula (I) to Isoflualanam is 1:35-18:1, the co-toxicity coefficient of the control effect on Spodoptera litura is greater than 120, showing a synergistic effect.

[0128] Table 1 The results of toxicity test of different ratios of the compound of formula (I) and Isoflualanam against Spodoptera litura

[0129]

[0130]

[0131] The results in Table 2 show that when the mass ratio of the compound of formula (I) to Cybenzoxasulfy is 1:45-25:1, the co-toxicity coefficient of the control effect on Spodoptera litura is greater than 80, showing an additive or synergistic effect. When the mass ratio of the compound of formula (I) to Cybenzoxasulfy is 1:30-25:1, the co-toxicity coefficient of the control effect on Spodoptera litura is greater than 120, showing a synergistic effect.

[0132] Table 2 Toxicity test results of different ratios of the compound of formula (I) and Cybenzoxasulfyl to Spodoptera litura

[0133]

[0134] Field efficacy examples

[0135] Field trial 1

[0136] Test crops: Radish (green radish);

[0137] Test target: Spodoptera litura;

[0138] Experimental location: Cruciferous vegetable flower planting experimental field in Shangma Street, Chengyang District, Qingdao City, Shandong Province;

[0139] Trial date: September 24, 2023;

[0140] Application method: In the test field, a backpack electric sprayer was used to apply pesticides manually according to the design plan. The whole plant was sprayed first, and then the back of the leaves was sprayed. The water consumption was 100L / hm 2 .

[0141] Experimental environment: All experimental plots had uniform cultivation conditions, the same fertilizer and water management level, good water and fertilizer conditions, and sticky loam;

[0142] Test drug:

[0143] Table 3 Field test design and dosage

[0144]

[0145]

[0146] Test method: Apply the pesticide once during the peak period of Spodoptera litura (mostly 2nd to 4th instar).

[0147] Plot size and repetition: random block arrangement, plot size 20m 2 , each treatment was repeated 4 times.

[0148] Survey method: Randomly sample five points in each plot, hang 10 plants at each point, investigate the number of Spodoptera litura on all radishes, investigate the base number of insects before applying pesticides, and investigate the number of remaining insects 2 days and 7 days after applying pesticides.

[0149] Calculation formula and data analysis:

[0150]

[0151] Field efficacy test results:

[0152] The test results in Table 4 show that 2 days after application, 30% of the compound of formula (I)·isoflualanam suspension concentrate (5+25) and 16% of the compound of formula (I)·cybenzoxasulfyl dispersible oil suspension concentrate (3+13) showed good rapid effect on the radish moth, with the protective effects of 87.22% and 88.41%, respectively, which were significantly higher than the control single agent; 7 days after application, 30% of the compound of formula (I)·isoflualanam suspension concentrate (5+25) and 16% of the compound of formula (I)·cybenzoxasulfyl dispersible oil suspension concentrate (3+13) showed good persistent effect on the radish moth, with the protective effects of 90.16% and 91.46%, respectively, which were significantly higher than the control single agent.

[0153] Table 4 Field control effects of different treatment agents on cauliflower pieris

[0154]

[0155] Note: The above insect population base and control efficacy data are the average of 4 replicates, and the values ​​are rounded to two decimal places. Different letters after the control efficacy data in the same column indicate significant differences (P < 0.05).

[0156] Safety: During the test period and later observations, radishes grew normally and no obvious signs of phytotoxicity were observed.

[0157] The pesticide composition or the preparation obtained by compounding the present invention has significant prevention effect, and is superior to a single agent in delaying the generation of drug resistance and prolonging drug retention. In addition, no compound agent was found to cause pesticide damage to crops in the test, indicating that the obtained pesticide composition or preparation can reduce production costs and use costs and is safe for crops when the insecticide synergistic synergy is improved.

[0158] Although the present invention has been described in detail above with general instructions and specific implementation schemes, it is obvious to those skilled in the art that some modifications or improvements can be made on the basis of the present invention. Therefore, these modifications or improvements made without departing from the spirit of the present invention are within the scope of protection claimed by the present invention.

Claims

1. A pesticide composition, characterized in that: The invention comprises active ingredient A and active ingredient B, wherein the active ingredient A is a compound of formula (I) The active ingredient B is Isoflualanam or Cybenzoxasulfyl.

2. The pesticide composition according to claim 1, characterized in that: The mass ratio between the active ingredient A and the active ingredient B is 1:45 to 27:

1.

3. The pesticide composition according to claim 1, characterized in that: The mass ratio of the compound of formula (I) to Isoflualanam is 1:35 to 27:1; the mass ratio of the compound of formula (I) to Cybenzoxasulfyl is 1:45 to 25:

1.

4. The pesticide composition according to claim 1, characterized in that: The mass ratio of the compound of formula (I) to Isoflualanam is 1:35 to 18:1; the mass ratio of the compound of formula (I) to Cybenzoxasulfyl is 1:30 to 25:

1.

5. The pesticide composition according to claim 1, characterized in that: Based on the total mass of the pesticide composition being 100 wt%, the sum of the contents of the active ingredient A and the active ingredient B in the pesticide composition is 0.5% to 90%.

6. The pesticide composition according to claim 1, characterized in that: In addition to the active ingredients, the pesticide composition also includes agriculturally acceptable auxiliary ingredients, which are selected from one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoamers, solvents, preservatives, stabilizers, synergists or carriers.

7. The pesticide composition according to claim 6, characterized in that: The pesticide composition can be prepared into a formulation form permitted in agriculture, and the formulation form is selected from a solid formulation and / or a liquid formulation; Preferably, the solid preparation is selected from wettable powders and water-dispersible granules; the liquid preparation is selected from emulsifiable concentrates, aqueous emulsions, microemulsions, suspensions, suspoemulsions, and dispersible oil suspensions.

8. Use of the pesticide composition according to any one of claims 1 to 7 in preventing and controlling agricultural and forestry pests and sanitary pests.

9. The use according to claim 8, characterized in that: The agricultural and forestry pests and sanitary pests are lepidoptera pests.

10. The pesticide composition according to claim 1, characterized in that: The pesticide composition is applied to the pests to be controlled or the medium where they grow in an effective dose.

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