Receiving assembly, detection device and glucometer
By designing a receiving component including a lens, collimating optical element, spectroscopic element and photosensitive element, the problem of low signal-to-noise ratio in blood sugar detection is solved, and a higher detection sensitivity is achieved.
Patent Information
- Application Number
- CN202311077045.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2023-08-24
- Publication Date
- 2025-02-25
- Estimated Expiration
- 2043-08-24
AI Technical Summary
In the existing blood sugar detection technology, the photosensitive element will be disturbed by ambient light and Rayleigh scattered light when receiving Raman scattered light, resulting in a relatively low signal-to-noise of the Raman spectrum and insufficient blood sugar detection sensitivity.
A receiving assembly is designed, including a first lens, a collimating optical element, a spectroscopic element and a photosensitive element. The light emitted by the target object is collected through the first lens, the collimating optical element performs light collimation and stray light filtering, the spectrometer separates laser light and Raman scattered light, and the photosensitive element receives the Raman scattered light after spectroscopy.
It effectively reduces the interference of miscellaneous light, improves the signal-to-noise ratio of the Raman spectrum, and significantly improves the sensitivity of blood sugar detection.
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Figure CN119498829A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of blood sugar detection, and in particular to a receiving component, a detection device and a blood sugar meter. Background Art
[0002] High blood sugar (glucose in the blood) levels can cause various acute and long-term complications, such as kidney disease, nervous and circulatory system diseases, cardiovascular disease, blindness, stroke, etc. In related technologies, blood sugar testing includes three methods: invasive, minimally invasive, and non-invasive. Among them, invasive and minimally invasive methods can cause pain and discomfort to patients, and are accompanied by potential risks such as infection.
[0003] Based on this, the existing blood sugar test mainly promotes non-invasive methods, using Raman spectroscopy to perform non-destructive testing of human blood sugar. Laser is used to irradiate the patient's skin to generate Raman scattered light, and a photosensitive element is used to receive the Raman scattered light, thereby achieving blood sugar testing.
[0004] However, due to the presence of interfering light such as ambient light and Rayleigh scattered light, the photosensitive element receives stray light while receiving Raman scattered light, resulting in a low signal-to-noise ratio of the Raman spectrum and low sensitivity of blood glucose detection. Summary of the invention
[0005] The embodiment of the present invention discloses a receiving component, a detection device and a blood glucose meter, which can reduce the interference caused by stray light, improve the signal-to-noise ratio of Raman spectroscopy, and have a high sensitivity for blood glucose detection.
[0006] In a first aspect, an embodiment of the present invention discloses a receiving component, comprising a first lens, a collimating optical element, a spectroscopic element and a photosensitive element, wherein the first lens is used to collect light emitted by a target object and emit the light, wherein the light includes laser and Raman scattered light, the collimating optical element is disposed on one side of the first lens, the collimating optical element is used to collimate the light emitted by the first lens and then emit it, and to filter stray light in the Raman scattered light, the spectroscopic element is disposed on a side of the collimating optical element away from the first lens, the spectroscopic element is used to receive the light emitted by the collimating optical element, and diffract and split the light so that the laser and the Raman scattered light are emitted in different directions, and the photosensitive element is used to receive the Raman scattered light emitted after being split by the spectroscopic element.
[0007] As an optional implementation, in an embodiment of the present invention, the collimating optical element includes a light absorbing portion and a plurality of light transmitting holes, the plurality of light transmitting holes are arranged at intervals in the light absorbing portion, the extension direction of the light transmitting holes is the same as the direction of the light emitted by the first lens, the light absorbing portion is used to absorb stray light in the Raman scattered light, and the light transmitting holes are used to collimate the light emitted by the first lens and then emit it.
[0008] As an optional implementation manner, in an embodiment of the present invention, the optical density of the light absorbing portion is OD, and OD≥4.
[0009] As an optional implementation, in the embodiment of the present invention, the diameter of the light-transmitting hole is d, the extension length of the light-transmitting hole is h, the light collimation angle of the light-transmitting hole is θ, and tanθ=d / h.
[0010] As an optional implementation, in an embodiment of the present invention, the light also includes Rayleigh scattered light, the receiving component also includes a filter, the filter is arranged between the collimating optical element and the spectroscopic element, and the filter is used to filter the Rayleigh scattered light.
[0011] As an optional implementation, in an embodiment of the present invention, the receiving component also includes a second lens, which is arranged between the spectroscopic element and the photosensitive element, and the second lens is used to receive the Raman scattered light emitted by the spectroscopic element and focus the Raman scattered light onto the photosensitive element.
[0012] As an optional implementation, in an embodiment of the present invention, the second lens includes one of a Fresnel lens, a diffraction lens, and a super lens.
[0013] As an optional implementation, in an embodiment of the present invention, the first lens and the collimating optical element are arranged with an interval, or the first lens abuts against a side of the collimating optical element away from the beam splitting element.
[0014] In a second aspect, an embodiment of the present invention discloses a detection device, comprising a transmitting component and the receiving component of the first aspect, wherein the transmitting component is used to transmit laser light to the target object so that the target object emits the light.
[0015] In a third aspect, an embodiment of the present invention discloses a blood glucose meter, comprising the detection device of the second aspect.
[0016] Compared with the prior art, the embodiments of the present invention have at least the following beneficial effects:
[0017] In the embodiment of the present invention, the light emitted by the target object is collected by the first lens, and the light is emitted to the collimating optical element. The light is collimated by the collimating optical element and then emitted to the spectroscopic element. The spectroscopic element can diffract and split the light, so that the laser and Raman scattered light in the light are emitted in different directions, thereby separating the laser and Raman scattered light. The emitted Raman scattered light can be emitted to the photosensitive element, thereby using the Raman scattered light received by the photosensitive element to perform blood glucose detection, and the sensitivity of blood glucose detection is high. At the same time, when the light is processed by the collimating optical element, the collimating optical element can also filter the stray light in the Raman scattered light in the light, so that when the photosensitive element receives the Raman scattered light, the interference of the stray light can be reduced, and the signal-to-noise ratio of the Raman spectrum can be improved, thereby further improving the sensitivity of blood glucose detection. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this technical field, other drawings can be obtained based on these drawings without creative work.
[0019] Figure 1 It is a structural schematic diagram of a receiving component disclosed in Embodiment 1 of the present invention;
[0020] Figure 2 is a schematic structural diagram of a collimating optical element disclosed in Embodiment 1 of the present invention;
[0021] Figure 3 is a schematic diagram of the internal structure of a collimating optical element disclosed in Embodiment 1 of the present invention;
[0022] Figure 4 is a schematic structural diagram of the first lens and the collimating optical element abutting against each other as disclosed in the first embodiment of the present invention;
[0023] Figure 5 is a schematic diagram of the structure of the detection device disclosed in the second embodiment of the present invention;
[0024] Figure 6 It is a simplified structural diagram of the blood glucose meter disclosed in the third embodiment of the present invention.
[0025] Description of main reference numerals
[0026] 100, receiving component; 10, first lens; 11, collimating optical element; 11a, light absorbing part; 11b, light transmission hole; 12, spectroscopic element; 13, photosensitive element; 14, filter; 15, second lens; 200, detection device; 20, transmitting component; 300, blood glucose meter; a, target object. DETAILED DESCRIPTION
[0027] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0028] In the present invention, the directions or positional relationships indicated by the terms "upper", "lower", "left", "right", "front", "back", "top", "bottom", "inner", "outer", "middle", "vertical", "horizontal", "lateral", "longitudinal" and the like are based on the directions or positional relationships shown in the drawings. These terms are mainly used to better describe the present invention and its embodiments, and are not used to limit the indicated devices, elements or components to have a specific direction, or to be constructed and operated in a specific direction.
[0029] In addition, some of the above terms may be used to express other meanings in addition to indicating orientation or positional relationship. For example, the term "on" may also be used to express a certain dependency or connection relationship in some cases. For those skilled in the art, the specific meanings of these terms in the present invention can be understood according to specific circumstances.
[0030] In addition, the terms "installed", "set", "provided with", "connected", and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral structure; it can be a mechanical connection, or an electrical connection; it can be a direct connection, or an indirect connection through an intermediate medium, or it can be an internal connection between two devices, elements, or components. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0031] In addition, the terms "first", "second", etc. are mainly used to distinguish different devices, elements or components (the specific types and structures may be the same or different), and are not used to indicate or imply the relative importance and quantity of the indicated devices, elements or components. Unless otherwise specified, "plurality" means two or more.
[0032] The invention discloses a receiving component, a detection device and a blood glucose meter, which can reduce the interference caused by stray light, improve the signal-to-noise ratio of Raman spectrum, and have high sensitivity in blood glucose detection.
[0033] Embodiment 1
[0034] See also Figure 1, is a schematic structural diagram of a receiving component 100 provided in Embodiment 1 of the present invention, the receiving component 100 includes a first lens 10, a collimating optical element 11, a spectroscopic element 12 and a photosensitive element 13, the first lens 10 is used to collect light emitted by a target object a and emit light, the light includes laser and Raman scattered light, the collimating optical element 11 is arranged on one side of the first lens 10, the collimating optical element 11 is used to collimate the light emitted by the first lens 10 and then emit it, and to filter stray light in the Raman scattered light, the spectroscopic element 12 is arranged on the side of the collimating optical element 11 away from the first lens 10, the spectroscopic element 12 is used to receive the light emitted by the collimating optical element 11, and diffract and split the light so that the laser and the Raman scattered light are emitted in different directions, and the photosensitive element 13 is used to receive the Raman scattered light emitted by the spectroscopic element 12.
[0035] The target object a may be the user's skin. The laser is emitted to the user's skin by the laser. After the laser reaches the surface of the user's skin, it will be absorbed, reflected, and scattered by the skin components. The reflection includes the laser emitted by the laser, and the scattering includes Rayleigh scattered light and Raman scattered light. Figure 1 In the figure, the dotted line is used to represent the optical path of the receiving component 100.
[0036] Exemplarily, the photosensitive element 13 may be an APD (Avalanche Photon Diode) sensor or a SPAD (Single Photon Avalanche Diode) sensor. In this embodiment, the photosensitive element 13 may be an APD as an example.
[0037] In this embodiment, the first lens 10 is used to collect the light emitted by the target object a, and the light is emitted to the collimating optical element 11. The collimating optical element 11 is used to collimate the light and then emit it to the spectroscopic element 12. The spectroscopic element 12 can diffract and split the light, so that the laser and Raman scattered light in the light are emitted in different directions, thereby separating the laser and Raman scattered light. The emitted Raman scattered light can be emitted to the photosensitive element 13, thereby using the Raman scattered light received by the photosensitive element 13 to perform blood glucose detection, and the sensitivity of blood glucose detection is high. At the same time, when the light is processed by the collimating optical element 11, the collimating optical element 11 can also filter the stray light in the Raman scattered light in the light, so that when the photosensitive element 13 receives the Raman scattered light, the interference of the stray light can be reduced, and the signal-to-noise ratio of the Raman spectrum can be improved, thereby further improving the sensitivity of blood glucose detection.
[0038] In some embodiments, Figure 2 and Figure 3As shown, the collimating optical element 11 includes a light absorbing portion 11a and a plurality of light-transmitting holes 11b, wherein the plurality of light-transmitting holes 11b are arranged at intervals on the light absorbing portion 11a, and the extending direction of the light-transmitting holes 11b is the same as the direction of the light emitted from the first lens 10, and the light absorbing portion 11a is used to absorb stray light in the Raman scattered light, and the light-transmitting holes 11b are used to collimate the light emitted from the first lens 10 before emitting it. In this way, the light is transmitted through the light-transmitting holes 11b, and the light is offset in the light-transmitting holes 11b to achieve the collimation of the light, while the light absorbing portion 11a can absorb the stray light in the Raman scattered light, thereby reducing the interference of the stray light, improving the signal-to-noise ratio of the Raman spectrum, and further improving the sensitivity of blood sugar detection.
[0039] The material of the light absorbing portion 11 a may be an organic black matrix BM (Black Matrix) or other light absorbing materials, which may be selected according to actual conditions and is not specifically limited in this embodiment.
[0040] Optionally, the optical density of the light absorbing portion 11a is OD, OD≥4. If the optical density OD of the light absorbing portion 11a is less than 4, the effect of the light absorbing portion 11a absorbing the stray light in the Raman scattered light is poor, and part of the stray light cannot be absorbed by the light absorbing portion 11a, resulting in part of the stray light being emitted to the photosensitive element 13 along with the Raman scattered light, causing interference, the signal-to-noise ratio of the Raman spectrum is low, and the sensitivity of blood glucose detection is low. Therefore, the optical density OD of the light absorbing portion 11a can be OD≥4, and the light absorbing portion 11a can absorb as much stray light in the Raman scattered light as possible, reduce the interference of the stray light to the photosensitive element 13, and improve the signal-to-noise ratio of the Raman spectrum, thereby improving the sensitivity of blood glucose detection. And the optical density OD can be 4, 4.2, 4.4, 4.6, 4.8.5.0, etc., which is not specifically limited in this embodiment.
[0041] For example, the diameter of the light-transmitting hole 11b is d, the extension length of the light-transmitting hole 11b is h, the light collimation angle of the light-transmitting hole 11b is θ, and tanθ=d / h. In this way, when the light hits one open end of the light-transmitting hole 11b, the light is offset and collimated at the light collimation angle θ, and when it is emitted along the extension direction of the light-transmitting hole 11b, after passing a distance d, the offset amount d is generated along the diameter direction of the light-transmitting hole 11b, so that it can just be emitted from the other open end of the light-transmitting hole 11b, and will not be emitted to the light-absorbing part 11a around the light-transmitting hole 11b, ensuring that the light entering the light-transmitting hole 11b from one open end of the light-transmitting hole 11b can be completely emitted from the other open end of the light-transmitting hole 11b, and the utilization rate of the light is high.
[0042] Considering the errors in processing and assembly, tanθ is usually approximately equal to d / h. For example, when θ=1° and d=50μm, h≈2.86mm.
[0043] In some embodiments, Figure 1As shown, the light also includes Rayleigh scattered light, and the receiving component 100 also includes a filter 14, which is arranged between the collimating optical element 11 and the spectroscopic element 12, and the filter 14 is used to filter the Rayleigh scattered light. In this way, by filtering the Rayleigh scattered light through the filter 14, interference caused by the Rayleigh scattered light can be avoided, the signal-to-noise ratio of the Raman spectrum can be improved, and thus the sensitivity of blood sugar detection can be improved.
[0044] Optionally, the receiving component 100 further includes a second lens 15, which is disposed between the spectroscopic element 12 and the photosensitive element 13, and is used to receive the Raman scattered light emitted by the spectroscopic element 12, and focus the Raman scattered light to the photosensitive element 13. In this way, by focusing the Raman scattered light to the photosensitive element 13 through the second lens 15, as much Raman scattered light emitted by the spectroscopic element 12 as possible can be directed to the photosensitive element 13, thereby improving the utilization rate of the Raman scattered light, and the photosensitive element 13 receives more Raman scattered light, which can improve the sensitivity of blood sugar detection.
[0045] Exemplarily, the second lens 15 includes one of a Fresnel lens, a diffraction lens, and a super lens. This embodiment provides a plurality of second lenses 15 with different structures, which can be selected according to actual conditions, and this embodiment does not specifically limit this.
[0046] Alternatively, if Figure 1 As shown, the first lens 10 and the collimating optical element 11 are spaced apart from each other, or as shown in FIG. Figure 4 As shown, the first lens 10 is in contact with the side of the collimating optical element 11 away from the beam splitting element 12. This embodiment provides a variety of arrangements of the first lens 10 and the collimating optical element 11, which can be selected according to actual conditions, and this embodiment does not specifically limit this. For example, if the first lens 10 and the collimating optical element 11 are arranged with an interval, the two are independent processed parts, and transportation and assembly are more flexible and changeable. If the first lens 10 and the collimating optical element 11 are in contact, the two can be independent processed parts or integrally formed parts.
[0047] The first embodiment of the present invention provides a receiving component 100, which collects the light emitted by the target object a through the first lens 10, emits the light to the collimating optical element 11, and uses the collimating optical element 11 to collimate the light and then emit it to the spectroscopic element 12. The spectroscopic element 12 can diffract and split the light, so that the laser and Raman scattered light in the light are emitted in different directions, thereby separating the laser and Raman scattered light, and the emitted Raman scattered light can be emitted to the photosensitive element 13, thereby using the Raman scattered light received by the photosensitive element 13 to perform blood glucose detection, and the sensitivity of blood glucose detection is high. At the same time, when the light is processed by the collimating optical element 11, the collimating optical element 11 can also filter the stray light in the Raman scattered light in the light, so that when the photosensitive element 13 receives the Raman scattered light, the interference of the stray light can be reduced, and the signal-to-noise ratio of the Raman spectrum can be improved, thereby further improving the sensitivity of blood glucose detection.
[0048] Embodiment 2
[0049] See also Figure 5 , which is a schematic diagram of the structure of a detection device 200 provided in the second embodiment of the present invention, the detection device 200 includes a transmitting component 20 and a receiving component 100 of the first embodiment, and the transmitting component 20 is used to transmit a laser to the target object a so that the target object a emits light.
[0050] The emitting component 20 includes a laser. The laser may be a vertical-cavity surface-emitting laser (VCSEL), which can emit multiple infrared spots simultaneously, or the emitting component 20 includes a laser and a diffractive optical element, and the laser may be an edge-emitting laser, which can emit a single infrared spot. The single infrared spot is diffused by using the diffractive optical element, so that the infrared spot is multiplied, and multiple infrared spots are emitted at a single time.
[0051] The second embodiment of the present invention provides a detection device 200, wherein the receiving component 100 can reduce the interference caused by stray light, improve the signal-to-noise ratio of the Raman spectrum, and has a high sensitivity for blood glucose detection.
[0052] Embodiment 3
[0053] See also Figure 6 , is a schematic structural diagram of a blood glucose meter 300 provided in the third embodiment of the present invention, and the blood glucose meter 300 includes the detection device 200 of the second embodiment.
[0054] Embodiment 3 of the present invention provides a blood glucose meter 300 having high blood glucose detection sensitivity.
[0055] A receiving component, a detection device and a blood glucose meter disclosed in the embodiments of the present invention are introduced in detail above. This article uses individual examples to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only used to help understand the receiving component, the detection device and the blood glucose meter of the present invention and their core ideas. At the same time, for those skilled in the art, according to the ideas of the present invention, there will be changes in the specific implementation methods and application scopes. In summary, the content of this specification should not be understood as a limitation on the present invention.
Claims
1. A receiving component, characterized in that: include: A first lens, the first lens is used to collect light emitted by the target object and emit the light, wherein the light includes laser light and Raman scattered light; A collimating optical element, the collimating optical element being disposed on one side of the first lens, the collimating optical element being used to collimate the light emitted from the first lens before emitting the light, and being used to filter stray light in the Raman scattered light; a beam splitter element, the beam splitter element being disposed on a side of the collimating optical element away from the first lens, the beam splitter element being used to receive the light emitted by the collimating optical element and to perform diffraction and beam splitting on the light so that the laser and the Raman scattered light are emitted in different directions; and A photosensitive element is used to receive the Raman scattered light emitted by the light splitting element.
2. The receiving assembly according to claim 1, characterized in that: The collimating optical element includes a light absorbing portion and a plurality of light transmitting holes, wherein the plurality of light transmitting holes are arranged at intervals on the light absorbing portion, and the extending direction of the light transmitting holes is the same as the direction in which the light is emitted from the first lens. The light absorbing portion is used to absorb stray light in the Raman scattered light, and the light transmitting holes are used to collimate the light emitted from the first lens and then emit it.
3. The receiving assembly according to claim 2, characterized in that: The optical density of the light absorbing part is OD, and OD≥4.
4. The receiving assembly according to claim 2, characterized in that: The diameter of the light-transmitting hole is d, the extension length of the light-transmitting hole is h, the light collimation angle of the light-transmitting hole is θ, and tanθ=d / h.
5. The receiving assembly according to any one of claims 1 to 4, characterized in that: The light also includes Rayleigh scattered light, and the receiving component also includes a filter, which is arranged between the collimating optical element and the beam splitting element, and is used to filter the Rayleigh scattered light.
6. The receiving assembly according to any one of claims 1 to 4, characterized in that: The receiving component also includes a second lens, which is arranged between the spectroscopic element and the photosensitive element, and is used to receive the Raman scattered light emitted by the spectroscopic element and focus the Raman scattered light onto the photosensitive element.
7. The receiving assembly according to claim 6, characterized in that: The second lens includes one of a Fresnel lens, a diffraction lens, and a super lens.
8. The receiving assembly according to any one of claims 1 to 4, characterized in that: The first lens and the collimating optical element are arranged at an interval, or the first lens abuts against a side of the collimating optical element away from the beam splitting element.
9. A detection device, characterized in that: It comprises a transmitting component and a receiving component as claimed in any one of claims 1 to 8, wherein the transmitting component is used to transmit laser to the target object so that the target object emits the light.
10. A blood glucose meter, characterized in that: Comprising the detection device as claimed in claim 9.
Citation Information
Patent Citations
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