Automatic cover opening and closing device for PCR (Polymerase Chain Reaction) eight-connection pipe

By designing the automatic opening and closing device of PCR eight-link tube, the problem of opening the cover of PCR reagent tube in the prior art is solved, and automated operation is achieved, reagent damage and sample contamination are avoided, and experimental efficiency and accuracy of results are improved.

CN119503705APending Publication Date: 2025-02-25DONGGUAN SONGSHAN LAKE CENT HOSPITAL (DONGGUAN SHILONG PEOPLES HOSPITAL DONGGUAN THIRD PEOPLES HOSPITAL DONGGUAN INST OF CARDIOVASCULAR DISEASES)
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Patent Information

Application Number
CN202411451100.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-10-17
Publication Date
2025-02-25

AI Technical Summary

Technical Problem

The tube cover of existing PCR reagents is not easy to open, which can easily cause reagent damage, sample contamination and inaccurate experimental results.

Method used

An automatic cover opening and closing device of PCR eight-link tube is designed. Through the coordinated work of the placement mechanism, cover closing mechanism, cover opening mechanism and cover opening mechanism, the automatic cover closing and opening of PCR eight-link tube is realized.

Benefits of technology

Automatic operation is realized, which avoids damage to the PCR octagonal tube and contamination of samples by manual operation, and improves experimental efficiency and accuracy of results.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to an automatic cover opening and closing device for a PCR eight-connection pipe, the automatic cover opening and closing device for the PCR eight-connection pipe comprises a placing mechanism, a cover closing mechanism, a cover pressing mechanism and a cover opening mechanism, the cover closing mechanism is mounted on one side of the placing mechanism, the cover pressing mechanism and the cover opening mechanism are respectively mounted on two sides of the placing mechanism, and the PCR eight-connection pipe is arranged on the placing mechanism. According to the automatic cover opening and closing device for the PCR eight-connection pipe, during cover closing, the containing mechanism drives the PCR eight-connection pipe to move to the cover closing mechanism, the pipe cover is closed to the upper end of the pipe barrel, the containing mechanism drives the PCR eight-connection pipe to rotate to be close to the cover pressing mechanism, the cover pressing mechanism presses the pipe cover to the pipe barrel, during cover opening, the containing mechanism drives the PCR eight-connection pipe to move to the cover opening mechanism, and the pipe cover is closed to the upper end of the pipe barrel. And the uncovering mechanism drives to separate the tube cover from the tube barrel, so that the PCR eight-connection tube is automatically covered or uncovered, and the damage to the PCR eight-connection tube or the pollution to a sample caused by manual operation is avoided.
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Description

Technical Field

[0001] The invention relates to the technical field of cell culture structures, in particular to an automatic cover opening and closing device for PCR eight-tube strips. Background Art

[0002] Existing PCR reagents are generally packaged in PCR tubes, which are placed in PCR tube racks. When the sample volume is large, the following problems may arise:

[0003] 1. It is not easy to open the lid. In order to prevent the loss of reagents, the tubes are covered very tightly. In addition to the necessary strength, opening the lid by hand requires more skills. When the number of specimens is particularly large, it greatly affects the work speed. Moreover, the longer the experimental operation time, the greater the impact of external temperature, which will bring unnecessary influence to the experimental results.

[0004] 2. Due to the small size of PCR tubes and the thin-walled PP material, they are easily deformed when the lid is opened by hand, which causes unnecessary effects on the experiment, such as uneven heating during amplification and poor amplification efficiency.

[0005] 3. Secondly, it is easy to contaminate the inside of the tube cover when opening the cover with bare hands, resulting in false positives or false negatives in the experimental results.

[0006] Some PCR tube cover opening devices are recorded in the currently disclosed patent documents, but these currently disclosed devices only have a simple cover opening function and cannot effectively realize the cover closing function. Summary of the invention

[0007] The main purpose of the present invention is to provide an automatic opening and closing device for PCR eight-tube strips to solve the above-mentioned technical problems, realize automatic closing or opening of the PCR eight-tube strips, and avoid damage to the PCR eight-tube strips or contamination of the samples by manual operation.

[0008] To achieve the above object, the present invention adopts the following technical solutions:

[0009] A PCR eight-tube automatic cover opening and closing device is used to open or close the cover of the PCR eight-tube strip, characterized in that:

[0010] The PCR eight-tube strip includes eight tubes, which are arranged equidistantly. The tubes include a tube barrel, a connection block, a tube cover and a connection rib. The two ends of the connection block are respectively connected to the upper end of the tube barrel and the edge of the tube cover. The tube cover is covered on the upper end of the tube barrel. The tube cover is provided with an inner tube and a lifting part. The inner tube is provided in the middle of the tube cover. The lifting part is provided at the end of the tube cover and is arranged opposite to the connection block. The connection rib is provided on the tube barrel. Every two adjacent tubes are connected through the connection block.

[0011] The automatic opening and closing device for PCR eight-tube strips comprises a placing mechanism, a covering mechanism, a capping mechanism and an opening mechanism. The covering mechanism is installed on one side of the placing mechanism, and the capping mechanism and the opening mechanism are respectively installed on both sides of the placing mechanism. The PCR eight-tube strips are placed on the placing mechanism. When closing the covers, the placing mechanism drives the PCR eight-tube strips to move to the covering mechanism, and closes the tube caps to the upper end of the tube barrel. The placing mechanism drives the PCR eight-tube strips to rotate close to the capping mechanism, and the capping mechanism presses the tube caps onto the tube barrel. When opening the covers, the placing mechanism drives the PCR eight-tube strips to move to the capping mechanism, and the capping mechanism drives the tube caps to be separated from the tube barrel.

[0012] As a preferred technical solution, the placement mechanism includes a placement moving component, a rotating component and an eight-tube placement seat, the eight-tube placement seat is installed on the rotating component, the rotating component drives the eight-tube placement seat to rotate, and the placement moving component drives the rotating component to move.

[0013] As a preferred technical solution, the cover closing mechanism includes a first cover closing moving assembly, a second cover closing moving assembly and a cover closing assembly, the first cover closing moving assembly drives the second cover closing moving assembly to move, and the second cover closing moving assembly drives the cover closing assembly to move.

[0014] As a preferred technical solution, the closing cover assembly includes a closing cover clamping unit and a closing cover flipping unit, wherein the closing cover flipping unit is installed above the closing cover clamping unit, the closing cover clamping unit clamps the tube, and the closing cover flipping unit adsorbs the tube cover and flips and presses it onto the tube.

[0015] As a preferred technical solution, the cover closing and flipping unit includes a cover closing and flipping cylinder, a cover closing and flipping block, a cover closing adsorption block and a cover closing air suction joint, the cover closing and flipping cylinder is installed on the cover closing moving seat, the cover closing adsorption block is installed on the cover closing and flipping block, the cover closing and air suction joint is installed on the cover closing adsorption block, the cover closing and flipping cylinder drives the cover closing and flipping block to rotate, the cover closing adsorption block is provided with a pipe cover fixing hole, the shape of the pipe cover fixing hole matches the outer surface of the pipe cover, the pipe cover fixing hole is provided with a pipe cover adsorption hole, the pipe cover adsorption holes are evenly distributed at the bottom of the pipe cover fixing hole, and the pipe cover adsorption holes are connected with the cover closing and air suction joint.

[0016] As a preferred technical solution, the capping mechanism includes a capping driving assembly, a capping lifting assembly and a capping assembly, wherein the capping driving assembly drives the capping lifting assembly to move, and the capping lifting assembly drives the capping assembly to rise and fall.

[0017] As a preferred technical solution, the gland assembly includes a gland shell, a gland fixed seat, a gland movable seat, a gland spring, a gland gasket and a pressure sensor. A gland chamber is arranged in the gland shell, the pressure sensor is installed on the top of the gland chamber, the gland fixed seat and the gland movable seat are arranged in the gland chamber, one end of the gland spring abuts against the gland fixed seat, and the other end abuts against the gland movable seat.

[0018] As a preferred technical solution, the cover opening mechanism includes an X-axis moving component, a Y-axis moving component, a Z-axis moving component and a cover opening component, the X-axis moving component drives the Y-axis moving component to move, the Y-axis moving component drives the Z-axis moving component to move, and the Z-axis moving component drives the cover opening component to move.

[0019] As a preferred technical solution, the cover opening assembly includes a cover opening mounting seat, a cover opening clamping unit and a cover opening unit, the cover opening clamping unit and the cover opening unit are installed on the cover opening mounting seat, the cover opening clamping unit clamps the tube, and the cover opening unit lifts the tube cover.

[0020] As a preferred technical solution, the cover opening unit includes a cover opening motor, a cover opening connecting seat, a cover opening screw, a cover opening guide rail, a cover opening moving seat and a cover opening guide block, the cover opening motor and the cover opening guide rail are installed on the cover opening mounting seat, the cover opening connecting seat is fixed on the cover opening moving seat, the cover opening connecting seat is connected to the cover opening screw, the cover opening motor drives the cover opening screw to rotate, and drives the cover opening moving seat to move along the cover opening guide rail.

[0021] The beneficial effects of the present invention are as follows: the above-mentioned automatic lid opening and closing device for PCR eight-tube strips, when closing the lids, the placing mechanism drives the PCR eight-tube strips to move to the lid closing mechanism, and closes the tube lids to the upper end of the tube tube, the placing mechanism drives the PCR eight-tube strips to rotate close to the capping mechanism, and the capping mechanism presses the tube lids onto the tube tube, and when opening the lids, the placing mechanism drives the PCR eight-tube strips to move to the lid opening mechanism, and the lid opening mechanism drives the tube lids to be separated from the tube tube, thereby realizing automatic lid closing or lid opening of the PCR eight-tube strips, avoiding damage to the PCR eight-tube strips or contamination of the samples by manual operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 This is a schematic diagram of the structure of the eight-tube PCR strip according to the present invention;

[0023] Figure 2 It is a top view of the automatic cover opening and closing device for PCR eight-tube strips according to the present invention;

[0024] Figure 3 It is a front view of the placement mechanism involved in the present invention;

[0025] Figure 4 A top view of the placement mechanism involved in the present invention;

[0026] Figure 5 It is a front view of the cover closing mechanism involved in the present invention;

[0027] Figure 6 A top view of the cover closing mechanism according to the present invention;

[0028] Figure 7 It is a structural schematic diagram of the cover adsorption block according to the present invention;

[0029] Figure 8 It is a front view of the capping mechanism involved in the present invention;

[0030] Fig. 9 A top view of the capping mechanism according to the present invention;

[0031] Fig.10 A cross-sectional view of a gland assembly according to the present invention;

[0032] Fig.11 It is a front view of the cover opening mechanism involved in the present invention;

[0033] Fig.12 A top view of the cover opening mechanism according to the present invention;

[0034] Fig.13 The present invention is a schematic structural diagram of a cover opening guide block. DETAILED DESCRIPTION

[0035] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0036] like Figure 1As shown, a PCR eight-tube strip 100 includes eight tubes 101, which are arranged equidistantly so that the device can test eight samples at a time. The tube 101 includes a tube barrel 102, a connecting block 106, a tube cover 103 and a connecting rib 107. The two ends of the connecting block 106 are respectively connected to the upper end of the tube barrel 102 and the edge of the tube cover 103 to prevent the tube cover 103 from being separated from the tube barrel 102. The tube cover 103 is covered on the upper end of the tube barrel 102, so that a seal is formed in the tube barrel 102 to prevent the sample in the tube barrel 102 from being contaminated. The connecting block 106 is concave in the middle and is made of a highly elastic material. When the tube cover 103 is closed, the connecting block 106 is concave in the middle. The concave part is folded in half so that the two ends of the concave part are abutted, thereby closing the tube cover 103. After opening the cover, the connecting block 106 is reset to separate the tube cover 103 from the tube tube 102. The tube cover 103 is provided with an inner tube 104 and a lifting part 105. The inner tube 104 is arranged in the middle of the tube cover 103. When the tube cover 103 is closed, the inner tube 104 abuts against the tube tube 102, thereby improving the sealing inside the tube tube 102. The lifting part 105 is arranged at the end of the tube cover 103 and is arranged opposite to the connecting block 106 to assist the operator in opening the tube cover 103. The connecting rib 107 is arranged on the tube tube 102. Every two adjacent tubes 101 are connected by the connecting block 107, thereby connecting 8 tubes 101.

[0037] like Figure 2 As shown, an automatic opening and closing device for PCR eight-tube strips is used to open or close the covers of PCR eight-tube strips, comprising a rack 1 and a placing mechanism 2, a closing mechanism 3, a capping mechanism 4 and an opening mechanism 5 installed on the rack 1, the closing mechanism 3 is installed on one side of the placing mechanism 2, the capping mechanism 4 and the opening mechanism 5 are installed on both sides of the placing mechanism 2, and the PCR eight-tube strips 100 are placed on the placing mechanism 2. When closing the covers, the placing mechanism 2 drives the PCR eight-tube strips 100 to move to the closing cover position. Mechanism 3 closes the tube cover 103 to the upper end of the tube barrel 102, the placing mechanism 2 drives the PCR eight-tube 100 to rotate close to the capping mechanism 4, and the capping mechanism 4 presses the tube cover 103 onto the tube barrel 102. When opening the cover, the placing mechanism 2 drives the PCR eight-tube 100 to move to the opening mechanism 5, and the opening mechanism 5 drives the tube cover 103 to separate from the tube barrel 102, thereby automatically closing or opening the cover of the PCR eight-tube, avoiding damage to the PCR eight-tube or contamination of the sample due to manual operation.

[0038] like Figure 3 and Figure 4As shown, the placement mechanism 2 includes a placement moving component 21, a rotating component 22 and an eight-tube placement seat 23. The eight-tube placement seat 23 is installed on the rotating component 22. The rotating component 22 drives the eight-tube placement seat 23 to rotate. The placement moving component 21 drives the rotating component 22 to move. The PCR eight-tube 100 is placed on the eight-tube placement seat 23, so that the rotating component 22 can be rotated to a suitable angle for closing or opening the lid. The placement moving component 21 includes a placement moving drive module 211, a placement moving bracket 212 and a placement moving seat 213. The placement moving drive module 211 is installed on the placement moving bracket 212. The placement moving drive module 211 drives the placement moving seat 213 to move, thereby driving the rotating component 22 to move. In this embodiment, the placement moving drive module 211 is a motor-driven screw movable module. The rotating component 22 includes a rotating cylinder 221 and a rotating seat 222. The rotating cylinder 221 drives the rotating seat 222 to rotate. The eight-tube placement seat 23 is installed on the rotating seat 222. The eight-tube placement seat 23 is provided with a placement hole 231. The eight placement holes 231 are arranged in order on the eight-tube placement seat 23. The placement holes 231 are connected to negative air pressure, so that the PCR eight-tube can be fixed on the eight-tube placement seat 23.

[0039] Please combine Figure 5 , Figure 6 and Figure 7As shown, the closing mechanism 3 includes a CCD camera (not shown in the figure), a closing base 31, a first closing moving assembly 32, a second closing moving assembly 33, a closing moving seat 34 and a closing assembly 35. The first closing moving assembly 32 is installed on the closing base 31. The first closing moving assembly 32 drives the second closing moving assembly 33 to move. The second closing moving assembly 33 drives the closing moving seat 34 to move. The closing assembly 35 is installed on the closing moving seat 34. The closing assembly 35 includes a closing clamping unit 37 and a closing flipping unit 36. The closing flipping unit 36 ​​is installed above the closing clamping unit 37. When closing the cover, the rotating cylinder 221 drives the rotating seat 222 to rotate, so that the tube 103 is close to the closing assembly 35, the closing clamping unit 37 clamps the tube 102, and the closing flipping unit 36 ​​adsorbs the tube cover 103 and flips it to press it on the tube 102. In this embodiment, the first cover moving assembly 32 and the second cover moving assembly 33 are motor-driven screw rod movable modules, and the cover flipping unit 36 ​​includes a cover flipping cylinder 361, a cover flipping block 362, a cover suction block 363 and a cover suction joint 364. The cover flipping cylinder 361 is installed on the cover moving seat 34, the cover suction block 363 is installed on the cover flipping block 362, the cover suction joint 364 is installed on the cover suction block 363, and the cover flipping cylinder 361 is installed on the cover flipping block 362. The cover-closing flip block 362 is driven to rotate, and a tube cover fixing hole 365 is provided on the cover-closing adsorption block 363. The shape of the tube cover fixing hole 365 matches the outer surface of the tube cover 103. The tube cover fixing hole 365 is provided with a tube cover adsorption hole 366. The tube cover adsorption holes 366 are evenly distributed at the bottom of the tube cover fixing hole 365. The tube cover adsorption holes 366 are connected to the cover-closing air suction joint 364. The cover-closing air suction joint 364 is connected to negative air pressure, so that the tube cover adsorption holes 366 can adsorb and fix the tube cover 103. The closing cover clamping unit 37 includes a closing cover clamping fixed plate 371, a closing cover clamping claw 373 and a closing cover clamping cylinder 372. The closing cover clamping fixed plate 371 is fixed on the closing cover moving seat 34, and the closing cover clamping cylinder 372 is installed on the closing cover clamping fixed plate 371. The closing cover clamping cylinder 372 drives the two closing cover clamping claws 373 to move relative to each other, thereby clamping the tube 102.

[0040] When closing the cover, the CCD camera takes a picture of the first tube 101 to identify that the angle between the tube 102 and the tube cover 103 on the first tube 101 is α. Then, the first cover moving assembly 32 and the second cover moving assembly 33 are driven according to the position of the first tube 101 to move the cover clamping jaws 373 to the two sides of the first tube 101. The cover clamping cylinder 372 drives the two cover clamping jaws 373 to move relative to each other, thereby clamping the tube 102. The cover flipping cylinder 361 drives the cover to flip. The cover flip block 362 rotates (180°-α), the tube cover 103 enters the tube cover fixing hole 365, and the tube cover adsorption hole 366 is connected to negative pressure to adsorb and fix the tube cover 103. The cover flip cylinder 361 continues to drive the cover flip block 362 to rotate until the inner tube 104 is embedded in the tube barrel 102, that is, the tube cover 103 is loosely covered on the tube barrel 102. The above steps are repeated 8 times for the PCR eight-tube strip 100, so that the tube covers 103 are loosely covered on the tube barrel 102 for all 8 tubes 101.

[0041] like Figure 8 , Fig. 9 and Fig.10 As shown, the capping mechanism 4 includes a capping support 41, a capping drive assembly 42, a capping lifting assembly 43 and a capping assembly 44. The capping drive assembly 42 is installed on the capping support 41, and the capping drive assembly 42 drives the capping lifting assembly 43 to move. The capping assemblies 44 are all connected to the capping lifting assembly 43. The capping lifting assembly 43 drives the capping assembly 44 to rise and fall. The capping clamping structure 45 is installed at the lower end of the capping assembly 44, and the capping assembly 44 drives the tube cover 103 to be pressed onto the tube 102.

[0042] The pressure cap driving assembly 42 includes a pressure cap driving motor 421, a pressure cap driving active wheel 422, a pressure cap driving driven wheel 423, a pressure cap driving belt 424, a pressure cap driving guide rail 425 and a pressure cap driving base 426. The pressure cap driving motor 421 and the pressure cap driving guide rail 425 are installed on the pressure cap driving base 426. The pressure cap driving active wheel 422 and the pressure cap driving driven wheel 423 are rotatably installed on the two ends of the pressure cap driving base 426 respectively. The pressure cap driving active wheel 422 is connected to the pressure cap driving driven wheel 423 through the pressure cap driving belt 424. The pressure cap lifting assembly 43 is connected to the pressure cap driving belt 424. The pressure cap driving motor 421 drives the pressure cap driving active wheel 422 to rotate, drives the pressure cap driving belt 424 to transmit between the pressure cap driving active wheel 422 and the pressure cap driving driven wheel 423, and drives the pressure cap lifting assembly 43 to move along the pressure cap driving guide rail 425.

[0043] The pressure cover lifting assembly 43 includes a pressure cover moving seat 431, a pressure cover lifting seat 434, a pressure cover lifting cylinder 432 and a pressure cover lifting guide rail 433. The pressure cover lifting cylinder 432 and the pressure cover lifting guide rail 433 are installed on the pressure cover moving seat 431. The pressure cover lifting cylinder 432 drives the pressure cover lifting seat 434 to move along the pressure cover lifting guide rail 433. The pressure cover assembly 44 and the pressure cover clamping structure 45 are installed on the pressure cover lifting seat 434.

[0044] The gland assembly 44 includes a gland shell 441, a gland fixed seat 443, a gland movable seat 442, a gland spring 444, a gland gasket 445 and a pressure sensor 446. A gland chamber 4411 is provided in the gland shell 441, and the pressure sensor 446 is installed on the top of the gland chamber 4411. The gland fixed seat 443 and the gland movable seat 442 are provided in the gland chamber 4411. One end of the gland spring 444 abuts against the gland fixed seat 443, and the other end abuts against the gland movable seat 442. In particular, the lower end of the gland fixed seat 443 is provided with a second limiting column 4431, the upper end of the gland movable seat 442 is provided with a first limiting column 4432, and the gland spring 444 is provided with a second limiting column 4432. The two ends are respectively sleeved on the second limiting column 4431 and the first limiting column 4432 to fix the pressure cover spring 444 and ensure the central axis degree of the compression of the pressure cover spring 444 to avoid deviation during the compression of the pressure cover spring 444. The pressure cover gasket 445 is installed on the lower end of the pressure cover movable seat 442, so that the pressure cover gasket 445 is in flexible contact with the tube cover 103 to avoid the tube cover 103 from being compressed and deformed. A limiting ring 4412 is provided at the lower end of the pressure cover shell 441 to allow the pressure cover gasket 445 to extend while limiting the pressure cover movable seat 442 from leaving the pressure cover shell 441. The pressure sensor 446 senses the pressure change of the pressure cover spring 444 to determine whether the tube cover 103 is pressed tightly on the tube 102.

[0045] During capping, the rotating cylinder 221 drives the rotating seat 222 to rotate, so that the eight-tube placement seat 23 rotates to be flush with the capping drive assembly 42. At this time, the PCR eight-tube 100 is placed under the capping assembly 44, and the capping drive assembly 42 is driven to place the first tube 101 under the capping assembly 44. The capping lifting cylinder 432 drives the capping lifting seat 434 to move downward along the capping lifting guide rail 433, and the capping gasket 445 contacts the tube cover 103. The capping lifting cylinder 432 is continuously driven, and the capping spring 444 is compressed to press the tube cover 103 against the tube 102. When the pressure sensor 446 recognizes that the pressure on the capping fixing seat 443 is steadily increased, the tube cover 103 has been pressed.

[0046] like Fig.11 , Fig.12 and Fig.13As shown, the cover opening mechanism 5 includes a cover opening base 51, an X-axis moving assembly 52, an X-axis moving seat 53, a Y-axis moving assembly 54, a Y-axis moving seat 55, a Z-axis moving assembly 56, a Z-axis moving seat 57 and a cover opening assembly 58. The X-axis moving assembly 52 is installed on the cover opening base 51, the Y-axis moving assembly 54 is installed on the X-axis moving seat 53, the Z-axis moving assembly 56 is installed on the Y-axis moving seat 55, and the cover opening assembly 58 is installed on the Z-axis moving seat 57. The X-axis moving assembly 52 drives the X-axis moving seat 53 to move, the Y-axis moving assembly 54 drives the Y-axis moving seat 55 to move, and the Z-axis moving assembly 56 drives The Z-axis moving seat 57 moves. In the present embodiment, the X-axis moving assembly 52, the Y-axis moving assembly 54 and the Z-axis moving assembly 56 are motor-driven lead screw interactive modules. The cover opening assembly 58 includes a cover opening mounting seat 581, a cover opening clamping unit 583 and a cover opening unit 582. The cover opening clamping unit 583 and the cover opening unit 582 are mounted on the cover opening mounting seat 581. The cover opening clamping unit 583 is aligned with the cover opening unit 582. A slot 5811 is provided on the cover opening mounting seat 581 for the tube 100 to pass through. The cover opening clamping unit 583 clamps the tube 102, and the cover opening unit 582 lifts the tube cover 103.

[0047] The cover opening unit 582 includes a cover opening motor 5821, a cover opening connection seat 5822, a cover opening screw rod 5823, a cover opening guide rail 5824, a cover opening moving seat 5825 and a cover opening guide block 5826. The cover opening motor 5821 and the cover opening guide rail 5824 are installed on the cover opening mounting seat 581, the cover opening connection seat 5822 is fixed on the cover opening moving seat 5825, the cover opening connection seat 5822 is connected to the cover opening screw rod 5823, the cover opening motor 5821 drives the cover opening screw rod 5823 to rotate, drives the cover opening moving seat 5825 to move along the cover opening guide rail 5824, thereby driving The cover opening guide block 5826 lifts the tube cover 103. The cover opening guide block 5826 is provided with a guide slope. When opening the cover, the guide slope abuts against the lifting portion 105, thereby driving the tube cover 103 away from the tube 102. Specifically, the guide slope includes a first straight line 58261, a first curve 58262, a second straight line 58263, a second curve 58264 and a third straight line 58265. The first straight line 58261, the first curve 58262, the second straight line 58263, the second curve 58264 and the third straight line 58265 are connected end to end in sequence, and the cover opening When the tube cover 103 is opened, the lifting part 105 is first placed on the first straight line 58261, and then the cover opening motor 5821 is driven to move the lifting part 105 along the first straight line 58261, the first curve 58262, the second straight line 58263, the second curve 58264 and the third straight line 58265 in sequence to open the tube cover 103. In particular, the height difference between the beginning and the end of the second straight line 58263 is the height of the inner tube 104, so that the tube cover 103 can be accurately separated. The first curve 58262 is set between the first straight line 58261 and the second straight line 58263 and the second straight line 58265 are set between the first straight line 58261 and the second straight line 58263. The curve 58264 is arranged between the second straight line 58263 and the third straight line 58265, so that the connection between the first straight line 58261 and the second straight line 58263 and between the second straight line 58263 and the third straight line 58265 is smoother, and the lifting part 105 is prevented from being clamped between the first straight line 58261 and the second straight line 58263 and between the second straight line 58263 and the third straight line 58265. The third straight line 58265 is arranged to ensure that the inner cylinder 104 is separated from the tube 102, so that the connecting block 106 opens the tube 102. The cover opening clamping unit 583 includes a cover opening clamping jaw 5822 and a cover opening clamping cylinder 5821. The cover opening clamping cylinder 5821 drives the two cover opening clamping jaws 5822 to move relative to each other, so as to clamp the tube 102.

[0048] The above-described embodiments are only preferred examples of the present invention and are not intended to limit the scope of implementation of the present invention. Therefore, any equivalent changes or modifications made according to the structures, features and principles described in the scope of the patent application of the present invention should be included in the scope of the patent application of the present invention.

Claims

1. An automatic opening and closing device for PCR eight-tube strips, used for opening or closing the covers of PCR eight-tube strips, characterized in that: The PCR eight-tube strip includes eight tubes, which are arranged equidistantly. The tubes include a tube barrel, a connection block, a tube cover and a connection rib. The two ends of the connection block are respectively connected to the upper end of the tube barrel and the edge of the tube cover. The tube cover is covered on the upper end of the tube barrel. The tube cover is provided with an inner tube and a lifting part. The inner tube is provided in the middle of the tube cover. The lifting part is provided at the end of the tube cover and is arranged opposite to the connection block. The connection rib is provided on the tube barrel. Every two adjacent tubes are connected through the connection block. The automatic opening and closing device for PCR eight-tube strips comprises a placing mechanism, a covering mechanism, a capping mechanism and an opening mechanism. The covering mechanism is installed on one side of the placing mechanism, and the capping mechanism and the opening mechanism are respectively installed on both sides of the placing mechanism. The PCR eight-tube strips are placed on the placing mechanism. When closing the covers, the placing mechanism drives the PCR eight-tube strips to move to the covering mechanism, and closes the tube caps to the upper end of the tube barrel. The placing mechanism drives the PCR eight-tube strips to rotate close to the capping mechanism, and the capping mechanism presses the tube caps onto the tube barrel. When opening the covers, the placing mechanism drives the PCR eight-tube strips to move to the capping mechanism, and the capping mechanism drives the tube caps to be separated from the tube barrel.

2. The automatic cover opening and closing device for PCR eight-tube strips according to claim 1, characterized in that: The placement mechanism includes a placement moving component, a rotating component and an eight-tube placement seat, the eight-tube placement seat is installed on the rotating component, the rotating component drives the eight-tube placement seat to rotate, and the placement moving component drives the rotating component to move.

3. The automatic cover opening and closing device for PCR eight-tube strips according to claim 1, characterized in that: The cover closing mechanism comprises a first cover closing moving assembly, a second cover closing moving assembly and a cover closing assembly, wherein the first cover closing moving assembly drives the second cover closing moving assembly to move, and the second cover closing moving assembly drives the cover closing assembly to move.

4. The automatic cover opening and closing device for PCR eight-tube strips according to claim 3, characterized in that: The cover closing assembly includes a cover closing clamping unit and a cover closing flipping unit. The cover closing flipping unit is installed above the cover closing clamping unit. The cover closing clamping unit clamps the tube, and the cover closing flipping unit absorbs the tube cover and flips and presses it onto the tube.

5. The automatic cover opening and closing device for PCR eight-tube strips according to claim 4, characterized in that: The cover closing and flipping unit includes a cover closing and flipping cylinder, a cover closing and flipping block, a cover closing adsorption block and a cover closing air suction joint, the cover closing and flipping cylinder is installed on the cover closing moving seat, the cover closing adsorption block is installed on the cover closing and flipping block, the cover closing air suction joint is installed on the cover closing adsorption block, the cover closing and flipping cylinder drives the cover closing and flipping block to rotate, the cover closing adsorption block is provided with a pipe cover fixing hole, the shape of the pipe cover fixing hole matches the outer surface of the pipe cover, the pipe cover fixing hole is provided with a pipe cover adsorption hole, the pipe cover adsorption holes are evenly distributed at the bottom of the pipe cover fixing hole, and the pipe cover adsorption holes are connected with the cover closing and suction joint.

6. The automatic opening and closing device for eight PCR tubes according to claim 1, characterized in that: The capping mechanism comprises a capping driving component, a capping lifting component and a capping component. The capping driving component drives the capping lifting component to move, and the capping lifting component drives the capping component to rise and fall.

7. The automatic cover opening and closing device for PCR eight-tube strips according to claim 6, characterized in that: The gland assembly includes a gland shell, a gland fixed seat, a gland movable seat, a gland spring, a gland gasket and a pressure sensor. A gland chamber is arranged in the gland shell, the pressure sensor is installed on the top of the gland chamber, the gland fixed seat and the gland movable seat are arranged in the gland chamber, one end of the gland spring abuts against the gland fixed seat, and the other end abuts against the gland movable seat.

8. The automatic lid opening and closing device for eight PCR tube strips according to claim 1, characterized in that: The cover opening mechanism includes an X-axis moving component, a Y-axis moving component, a Z-axis moving component and a cover opening component. The X-axis moving component drives the Y-axis moving component to move, the Y-axis moving component drives the Z-axis moving component to move, and the Z-axis moving component drives the cover opening component to move.

9. The automatic cover opening and closing device for PCR eight-tube strips according to claim 8, characterized in that: The cover opening assembly includes a cover opening mounting seat, a cover opening clamping unit and a cover opening unit. The cover opening clamping unit and the cover opening unit are installed on the cover opening mounting seat. The cover opening clamping unit clamps the tube, and the cover opening unit lifts the tube cover.

10. The automatic cover opening and closing device for PCR eight-tube strips according to claim 9, characterized in that: The cover opening unit includes a cover opening motor, a cover opening connecting seat, a cover opening screw rod, a cover opening guide rail, a cover opening moving seat and a cover opening guide block. The cover opening motor and the cover opening guide rail are installed on the cover opening mounting seat, the cover opening connecting seat is fixed on the cover opening moving seat, the cover opening connecting seat is connected to the cover opening screw rod, the cover opening motor drives the cover opening screw rod to rotate, and drives the cover opening moving seat to move along the cover opening guide rail.

Citation Information

Patent Citations

  • Cover opening device for cover connecting pipe

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  • Cover plate grabbing device, cover closing mechanism and cover closing method thereof

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  • Capping device

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  • Sample pipetting and capping device

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