Blood purification treatment mode control method, controller, purification equipment and system

Abstract

The embodiment of the invention provides a control method of a blood purification treatment mode, a controller, purification equipment and a system, and solves the technical problems that in the prior art, the number of integrated treatment modes of blood purification equipment is small, operation is relatively tedious, and convenience is poor. According to the control method for the blood purification treatment mode, liquid loops corresponding to multiple pipeline assemblies can be combined by regulating and controlling starting or disconnection of multiple pumps, starting or disconnection of multiple functional devices and connection or disconnection of multiple connecting pipelines, and the liquid loops corresponding to the multiple pipeline assemblies can correspond to multiple treatment modes; therefore, more treatment modes are integrated on one blood purification device, and integration and use convenience of the blood purification device are improved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a control method, a controller, a purification device and a system for a blood purification treatment mode. Background Art

[0002] The blood purification equipment draws human blood out of the body, then filters out specific molecular substances in the blood, and then returns the purified blood to the human body to achieve the effect of disease treatment.

[0003] Continuous blood purification equipment is one of the commonly used blood purification equipment. It can remove excess water in the body, remove metabolic waste and toxins in the body, correct water and electrolyte disorders, ensure nutritional support, promote kidney function recovery, and remove various cytokines and inflammatory mediators.

[0004] Blood purification treatment is divided into a variety of treatment modes, such as slow continuous ultrafiltration, continuous veno-venous hemofiltration, continuous veno-venous hemodialysis, continuous veno-venous hemodiafiltration, dual plasma molecular adsorption therapy, plasma adsorption, plasma exchange, dual plasma exchange, hemoperfusion, etc. Different blood purification treatment modes are suitable for different patients. In order to meet the needs of clinical use, although blood purification equipment can integrate a variety of blood purification treatment modes. However, the number of treatment modes that can be integrated is relatively small, and it is difficult to achieve a collection of more treatment modes. When the treatment modes of multiple patients in an intensive care unit are different, multiple blood purification devices are often required to meet the treatment needs, which greatly increases the cost, and the operation is relatively cumbersome and inconvenient.

[0005] In addition, for patients who need to receive two different treatment modes, it is difficult for operators to switch between different treatment modes on the same blood purification device, resulting in inconvenience in operation. Summary of the invention

[0006] In order to solve the above technical problems, the present invention is proposed. The embodiments of the present invention provide a control method, controller, purification device and system for blood purification treatment mode, which solves the technical problems that the number of treatment modes integrated in the blood purification device in the prior art is small, the operation is relatively cumbersome and the convenience is poor.

[0007] As a first aspect of the present invention, the present invention provides a control method for a blood purification treatment mode, which is applicable to a blood purification system, wherein the blood purification system comprises: a plurality of pumps, at least one functional device, and a plurality of connecting pipes connected between the pumps and between the pumps and the functional device;

[0008] Wherein, the control method comprises:

[0009] Acquire a target treatment mode input by a user, where the target treatment mode is one or more treatment modes among a plurality of preset treatment modes;

[0010] Determine a target pipeline component matching the target treatment mode according to the target treatment mode, the target pipeline component comprising: a target function device, a target pump and a plurality of target connecting pipelines;

[0011] Acquiring treatment data corresponding to the target treatment mode, and calculating a target opening degree of each target pump according to the treatment data and performance parameters of the target pump;

[0012] The target pump is started up according to the target opening degree of each target pump, so as to control the conduction of a plurality of target connecting pipelines to form a liquid circuit corresponding to the target treatment mode.

[0013] In one embodiment of the present invention, obtaining the target treatment mode input by the user includes:

[0014] Get the target treatment type input by the user;

[0015] Determining a plurality of preset treatment modes corresponding to the target treatment type according to the target treatment type, so that the plurality of preset treatment modes are displayed on a display operation screen for a user to select a target treatment mode;

[0016] Gets the target treatment mode selected by the user.

[0017] In one embodiment of the present invention, the blood purification system includes a plurality of blood treatment components, and the plurality of blood treatment components correspond one-to-one to a plurality of treatment types;

[0018] Wherein, determining a target pipeline component matching the target treatment mode according to the target treatment mode includes:

[0019] According to the target treatment mode, determining a target treatment type corresponding to the target treatment mode from among the multiple treatment types;

[0020] According to the target treatment type, determining a target blood treatment component corresponding to the target treatment type from among the plurality of blood treatment components;

[0021] According to the treatment data of the target treatment mode, a target functional device, a target pump and a target connecting pipeline corresponding to the target treatment mode are determined in the target blood treatment component.

[0022] In one embodiment of the present invention, the blood purification system further comprises: at least one pipeline selection valve, the pipeline selection valve having at least two valve ports, each of the valve ports being connected to one of the connecting pipelines;

[0023] Wherein, the starting of the target pump is controlled according to the target opening of the target pump to control the conduction of the plurality of target connecting pipelines, including:

[0024] Determining a target pipeline selection valve according to the target connecting pipeline;

[0025] The target pipeline selection valve is controlled to conduct the target connecting pipeline, and the target pipeline selection valve is controlled to cut off a reference connecting pipeline, wherein the reference connecting pipeline is a connecting pipeline other than the target connecting pipeline among a plurality of connecting pipelines correspondingly connected to the target pipeline selection valve.

[0026] In one embodiment of the present invention, the treatment types include: hemodialysis, plasma exchange, plasma adsorption and plasma perfusion CRRT treatment, plasma therapy and hemoperfusion.

[0027] In one embodiment of the present invention, the preset treatment modes corresponding to the CRRT treatment include: continuous venovenous hemofiltration pre-dilution (CVVH-pre), continuous venovenous hemofiltration post-dilution (CVVH-post), continuous venovenous hemofiltration pre-post mixed dilution (CVVH-Mix), continuous venovenous hemodiafiltration pre-dilution (CVVHDF-pre), continuous venovenous hemodiafiltration post-dilution (CVVHDF-post), continuous venovenous hemodiafiltration pre-post mixed dilution (CVVHDF-Mix), continuous venovenous hemodialysis (CVVHD), slow continuous ultrafiltration (SCUF);

[0028] The preset treatment modes corresponding to the plasma therapy include: plasma exchange (PE), double filtration plasma exchange (DFPP), paired plasma filtration adsorption (CPFA), plasma adsorption (PA), dual plasma molecular adsorption system (DPMAS), molecular adsorption recirculation system (MARS), plasma separation adsorption system (FPSA), single pass albumin dialysis (SPAD), repeated albumin dialysis (RAD), plasma filtration dialysis (PDF);

[0029] The preset treatment modes corresponding to the blood perfusion include: blood perfusion (HP).

[0030] As a second aspect of the present invention, the present invention further provides a controller for a blood purification treatment mode, comprising: a data acquisition module, for acquiring a target treatment mode input by a user, wherein the target treatment mode is one or more treatment modes among a plurality of preset treatment modes;

[0031] A first determination module is used to determine a target pipeline component matching the target treatment mode according to the target treatment mode, wherein the target pipeline component includes: a target function device, a target pump, and a plurality of target connecting pipelines;

[0032] a calculation module, used for acquiring treatment data corresponding to the target treatment mode, and calculating a target opening degree of each of the target pumps according to the treatment data and the performance parameters of the target pump;

[0033] A control module is used to control the start-up of the target pump according to the target opening of the target pump, so as to control the conduction of the plurality of target connecting pipelines to form a liquid circuit corresponding to the target treatment mode.

[0034] As the third aspect of the present invention, the present invention also provides a blood purification device, comprising: multiple pumps and the controller described above; the blood purification device and at least one functional device, and multiple connecting pipelines connected between the pumps and between the pumps and the functional devices together constitute a blood purification system.

[0035] In one embodiment of the present invention, the blood purification device further comprises: at least one pipeline selection valve, the pipeline selection valve having at least two valve ports, each of the valve ports being connected to one of the connecting pipelines.

[0036] As a fourth aspect of the present invention, the present invention further provides a blood purification system, the blood purification system comprising: the blood purification device described above and at least one functional device, and a plurality of connecting pipes connected between the pumps and between the pumps and the functional devices;

[0037] When the treatment type is CRRT treatment, the corresponding functional device is a dialyzer and / or a filter;

[0038] When the treatment type is plasma therapy, the corresponding functional device is any one or more combinations of a plasma separator, a plasma component separator, and a plasma adsorber;

[0039] When the treatment type is blood perfusion, the corresponding functional device is a perfusion device.

[0040] The present invention provides a control method for a blood purification treatment mode, wherein the blood purification system included in the blood purification device includes five pumps, multiple functional devices, and multiple connecting pipelines connected between the pumps and between the pumps and the functional devices. By determining the target functional device, the target pump, and the target pipeline according to the target treatment mode input by the user, and calculating the target opening of the target pump according to the treatment data of the target treatment mode, and controlling the start of the target pump and the conduction of the target pipeline according to the target opening to form a liquid circuit corresponding to the target treatment mode, the patient can be treated according to the target treatment mode. By regulating the start or disconnection of the pump, the start or disconnection of the functional device, and the conduction or cutoff of multiple connecting pipelines, the liquid circuits corresponding to multiple pipeline components can be combined, and the liquid circuits corresponding to multiple pipeline components can correspond to multiple treatment modes, thereby realizing the integration of more treatment modes on a blood purification device, improving the integration and convenience of use of the blood purification device. BRIEF DESCRIPTION OF THE DRAWINGS

[0041] The above and other purposes, features and advantages of the present invention will become more apparent by describing the embodiments of the present invention in more detail in conjunction with the accompanying drawings. The accompanying drawings are used to provide a further understanding of the embodiments of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings, the same reference numerals generally represent the same components or steps.

[0042] Figure 1 The figure shows a pipeline diagram of a blood treatment component corresponding to CRRT treatment, provided by an embodiment of the present invention, where the target treatment type is CRRT treatment.

[0043] Figure 2 Shown is a flow chart of a method for controlling a blood purification treatment mode provided by an exemplary embodiment of the present invention.

[0044] Figure 3a Shown is a piping diagram of a fluid circuit corresponding to hemoperfusion (HP), a target treatment mode provided by an exemplary embodiment of the present invention.

[0045] Figure 3b Shown is a piping diagram of a fluid circuit corresponding to plasma exchange (PE) when a target treatment mode is provided according to an exemplary embodiment of the present invention.

[0046] Figure 3c Shown is a piping diagram of a fluid circuit corresponding to plasma adsorption (PA) in which the target treatment mode provided by an exemplary embodiment of the present invention is plasma adsorption.

[0047] Figure 4 Shown is a flow chart of a method for controlling a blood purification treatment mode provided by another exemplary embodiment of the present invention.

[0048] Figure 5 Shown is a flow chart of a method for controlling a blood purification treatment mode provided by another exemplary embodiment of the present invention.

[0049] Figure 6 Shown is a piping diagram of a fluid circuit corresponding to continuous venovenous hemodialysis (CVVHD) as a target treatment mode provided by an exemplary embodiment of the present invention.

[0050] Figure 7 Shown is a piping diagram of a fluid circuit corresponding to continuous venovenous hemofiltration pre-dilution (CVVH-pre) in which a target treatment mode is provided according to an exemplary embodiment of the present invention.

[0051] Figure 8 Shown is a piping diagram of a fluid circuit corresponding to continuous venovenous hemofiltration post-dilution (CVVH-post) in a target treatment mode provided by an exemplary embodiment of the present invention.

[0052] Fig. 9 Shown is a piping diagram of a fluid circuit corresponding to continuous venovenous hemofiltration pre-post mixed dilution (CVVH-Mix) for a target treatment mode provided by an exemplary embodiment of the present invention.

[0053] Fig.10 Shown is a piping diagram of a fluid circuit corresponding to continuous venovenous hemodiafiltration pre-dilution (CVVHDF-pre) in a target treatment mode provided by an exemplary embodiment of the present invention.

[0054] Fig.11 Shown is a piping diagram of a fluid circuit corresponding to continuous venovenous hemodiafiltration-post-dilution (CVVHDF-post) in which a target treatment mode is provided according to an exemplary embodiment of the present invention.

[0055] Fig.12 Shown is a piping diagram of a fluid circuit corresponding to continuous venovenous hemodiafiltration pre-post mixed dilution (CVVHDF-Mix) in which a target treatment mode is provided according to an exemplary embodiment of the present invention.

[0056] Fig.13 Shown is a piping diagram of a fluid circuit corresponding to slow continuous ultrafiltration (SCUF) provided by an exemplary embodiment of the present invention when the target treatment mode is slow continuous ultrafiltration.

[0057] Fig.14 Shown is a working block diagram of a controller of a blood purification treatment mode provided by an exemplary embodiment of the present invention.

[0058] Fig.15 Shown is a working block diagram of an electronic device provided by an exemplary embodiment of the present invention.

[0059] Reference numerals:

[0060] 11-first flow pump, 12-second flow pump, 13-third flow pump, 14-fourth flow pump, 2-blood pump, 51-first pipeline selection valve, 52-second pipeline selection valve, 61-dialyzer, 62-plasma separator, 63-adsorbent, 64-perfusion device, 7-bubble monitor, 8-heater, 81-first replacement pipeline, 82-second replacement pipeline; 71-first adsorption pipeline, 72-second adsorption pipeline, 91-blood extraction pipeline, 92-blood return pipeline, 93-first CRRT pipeline, 94-second CRRT pipeline, 95-third CRRT pipeline, 96-fourth CRRT pipeline; 97-fifth CRRT pipeline, 98-sixth CRRT pipeline, 99-seventh CRRT pipeline, 41-first pressure sensor, 42-second pressure sensor, 43-third pressure sensor, 44-fourth pressure sensor. DETAILED DESCRIPTION

[0061] Below, the exemplary embodiments according to the present invention will be described in detail with reference to the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments of the present invention, and it should be understood that the present invention is not limited to the exemplary embodiments described here.

[0062] Exemplary Blood Purification Devices

[0063] As a first aspect of the present invention, the blood purification device provided by the present invention includes a device body and a display operation screen. The display operation screen is used to display the content that needs to be displayed during the operation of the blood purification device, such as displaying the treatment type integrated by the blood purification device and multiple preset treatment modes corresponding to each treatment type. The user can see the treatment type and multiple preset treatment modes corresponding to each treatment type on the display operation screen, and select the corresponding target treatment mode.

[0064] The blood purification equipment provided by the present invention also includes a plurality of flow pumps, a blood pump, and a pipeline selection valve.

[0065] The blood purification equipment, at least one functional device and a plurality of connecting pipelines together constitute a blood purification system, and the plurality of connecting pipelines are used to connect the flow pump, the blood pump and the functional device. Among them, the flow pump is used to pump out or pump in the liquid at a preset pump speed. The blood pump is used to extract the blood from the patient's body and transport it to the corresponding connecting pipeline. The pipeline selection valve is used to connect multiple connecting pipelines. For example, the pipeline selection valve is a three-way valve. The three-way valve has three pipeline selection valve ports, each of which is connected to a connecting pipeline. The conduction and cutoff of the connecting pipeline can be controlled by controlling the pipeline selection valve. In addition, the flow rate of the liquid flowing through the connecting pipeline can be controlled by controlling the opening of the pipeline selection valve. The functional device is a device for functionally processing the liquid in each preset treatment mode. For example, the functional device can be a dialyzer 61, a plasma separator 62, an adsorber 63, a perfusion device 64, etc.

[0066] Optionally, the blood purification system includes multiple blood treatment components, and the multiple blood treatment components correspond to multiple treatment types one by one. For example, the blood treatment component corresponding to the treatment type of CRRT treatment is a hemodialysis component: Figure 1 FIG. 1 is a pipeline diagram of a blood treatment component corresponding to CRRT treatment provided by an embodiment of the present invention. Figure 1As shown, the blood treatment components corresponding to CRRT treatment include a dialyzer 61, a blood drawing line 91, a blood return line 92 and a blood pump 2 arranged on the blood drawing line 91, the blood pump 2 is used to pump the blood in the blood drawing line 91 into the dialyzer 61, and the blood return line 92 is used to transport the dialyzed blood in the dialyzer 61 to the patient's body; a first CRRT line 93 and a first flow pump 11 arranged on the first CRRT line 93, the two ends of the first flow pump 11 are respectively connected to the first CRRT line 93 and the liquid storage bag; a second CRRT line 94, a first line selection valve 51 and a second flow pump 12, the two ends of the second flow pump 12 are respectively connected to the first CRRT line 93 and the first line selection valve 51, and the two ends of the second CRRT line 94 are respectively connected to the first line selection valve 51 and the liquid outlet of the dialyzer 61; a third CRRT line 95 and a third flow pump 13, one end of the third flow pump 13 is connected to the first CRRT pipeline 93 and the second pipeline selection valve 52, the other end of the third flow pump 13 is connected to one end of the third CRRT pipeline 95, and the other end of the third CRRT pipeline 95 is connected to the blood extraction pipeline 91 and the liquid inlet of the dialyzer 61; the sixth CRRT pipeline 98, the two ends of the sixth CRRT pipeline 98 are respectively connected to the first pipeline selection valve 51 and the third CRRT pipeline 95; the seventh CRRT pipeline 99, the two ends of the seventh CRRT pipeline 99 are respectively connected to the second pipeline selection valve 52 and the third CRRT pipeline 95; the fourth CRRT pipeline 96 and the fourth flow pump 14, the two ends of the fourth flow pump 14 are respectively connected to the liquid inlet of the dialyzer 61 and the liquid storage bag; the fifth CRRT pipeline 97, the two ends of the fifth CRRT pipeline 97 are respectively connected to the second pipeline selection valve 52 and the liquid outlet of the dialyzer 61.

[0067] By regulating the opening or closing of the first flow pump 11, the second flow pump 12, the third flow pump 13, the fourth flow pump 14, the first pipeline selection valve 51, and the second pipeline selection valve 52, the blood extraction line 91, the blood return line 92, the first CRRT line 93, the second CRRT line 94, the third CRRT line 95, the fourth CRRT line 96, the fifth CRRT line 97, the sixth CRRT line 98, and the seventh CRRT line 99 can be opened or closed to adapt to 8 treatment modes of hemodialysis. The eight treatment modes are: continuous venovenous hemofiltration pre-dilution (CVVH-pre), continuous venovenous hemofiltration post-dilution (CVVH-post), continuous venovenous hemofiltration pre-post mixed dilution (CVVH-Mix), continuous venovenous hemodiafiltration pre-dilution (CVVHDF-pre), continuous venovenous hemodiafiltration post-dilution (CVVHDF-post), continuous venovenous hemodiafiltration pre-post mixed dilution (CVVHDF-Mix), continuous venovenous hemodialysis (CVVHD), and slow continuous ultrafiltration (SCUF).

[0068] Optionally, the blood purification device further includes: a heater 8 and a bubble monitor 7 , wherein the heater 8 is used to heat the replacement fluid or the dialysate, and the bubble monitor 7 is used to monitor whether there are bubbles in the blood return line 92 .

[0069] Optionally, the blood purification equipment also includes: pressure sensors arranged on the connecting pipelines, such as a first pressure sensor 41 arranged on the blood drawing line 91 and before the blood pump 2, a second pressure sensor 42 arranged between the blood drawing line 91 and the blood pump 2, a third pressure sensor 43 arranged on the blood return line 92, and a fourth pressure sensor 44 arranged on the fourth CRRT line.

[0070] Exemplary Control Methods

[0071] As a second aspect of the present invention, the present invention provides a method for controlling a blood purification treatment mode, which is applicable to the blood purification system described above. Figure 2 FIG. 2 is a control method for a blood purification treatment mode provided by an embodiment of the present invention. As shown in FIG. 2 , the control method for a blood purification treatment mode includes the following steps:

[0072] S1: Obtain the target treatment mode input by the user.

[0073] Specifically, a plurality of preset treatment modes integrated in the blood purification device are stored in a preset database in advance, and the preset database stores treatment types, a plurality of preset treatment modes included in the treatment types, and liquid connection pipelines corresponding to each preset treatment mode.

[0074] Specifically, the specific method of obtaining the target treatment mode input by the user, that is, S1 (obtaining the target treatment mode input by the user) may include the following steps:

[0075] S11: Obtaining a target treatment type input by a user;

[0076] After the user starts the blood purification device, the display operation screen in the blood purification device displays the treatment type. The user selects the target treatment type, and the controller obtains the target treatment type input by the user.

[0077] Specifically, treatment types include CRRT therapy, plasma therapy, and hemoperfusion.

[0078] (1) The treatment modes corresponding to CRRT treatment include the following 8 treatment modes:

[0079] Continuous venovenous hemofiltration pre-dilution (CVVH-pre), continuous venovenous hemofiltration post-dilution (CVVH-post), continuous venovenous hemofiltration pre-post mixed dilution (CVVH-Mix), continuous venovenous hemodiafiltration pre-dilution (CVVHDF-pre), continuous venovenous hemodiafiltration post-dilution (CVVHDF-post), continuous venovenous hemodiafiltration pre-post mixed dilution (CVVHDF-Mix), continuous venovenous hemodialysis (CVVHD), slow continuous ultrafiltration (SCUF).

[0080] (2) The treatment modes corresponding to plasma therapy include the following 10 treatment modes:

[0081] Plasma exchange (PE), double filtration plasma exchange (DFPP), paired plasma filtration adsorption (CPFA), plasma adsorption (PA), dual plasma molecular adsorption system (DPMAS), molecular adsorption recirculating system (MARS), plasma separation adsorption system (FPSA), single pass albumin dialysis (SPAD), repeated albumin dialysis (RAD), plasma filtration dialysis (PDF).

[0082] (3) The treatment modes corresponding to plasma perfusion include the following:

[0083] Plasma perfusion (HP).

[0084] S12: determining a plurality of preset treatment modes corresponding to the target treatment type according to the target treatment type, so that the plurality of preset treatment modes are displayed on the display operation screen;

[0085] When the controller obtains the target treatment type input by the user, it will search the preset treatment mode that matches the target treatment type in the preset database according to the target treatment type. For example, when the target treatment type selected by the user is CRRT treatment, the corresponding preset treatment mode is the 8 treatment modes described above.

[0086] After determining the multiple preset treatment modes corresponding to the target treatment type, the controller sends the corresponding multiple preset treatment modes to the display operation screen, and the display operation screen displays the corresponding multiple preset treatment modes, for example, displaying the 8 treatment modes corresponding to CRRT treatment. When displaying the treatment mode, the Chinese name of the treatment mode can be displayed, or the English abbreviation corresponding to the treatment mode can be limited. For example, the 8 treatment modes displayed on the display operation screen are: CVVH-front, CVVH-back, CVVH-Mix, CVVHDF-front, CVVHDF-back, CVVHD, CVVHDF-Mix, CUF, SPAD, and RAD.

[0087] S13: Obtain the target treatment mode selected by the user.

[0088] When multiple preset treatment modes corresponding to the target treatment type are displayed on the display operation screen, the user can select the target treatment mode accordingly. When the user clicks the target treatment mode on the display operation screen, the controller can obtain the target treatment mode input by the user. For example, when the user clicks and selects CVVHDF-Mix on the display operation screen, the corresponding controller obtains the target treatment mode input by the user as: continuous venovenous hemodiafiltration pre-post mixed dilution (CVVHDF-Mix).

[0089] S2: determining a target pipeline assembly matching the target treatment mode according to the target treatment mode, wherein the target pipeline assembly includes a plurality of target pumps, a target function device, and a plurality of target connecting pipelines;

[0090] Specifically, the preset database stores the target pipeline components corresponding to each treatment mode, that is, the target pipeline components include the target pump, target function device and target connecting pipeline required for the target treatment mode. Therefore, after determining the target treatment mode input by the user, the corresponding target pipeline component can be matched in the preset database according to the target treatment mode.

[0091] For example, Figure 3a As shown, when the target treatment mode input by the user is: plasma perfusion mode, the target functional device corresponding to the plasma perfusion mode is the perfusion device 64, and the target pump is: blood pump 2. The target connecting pipelines are: blood extraction line 91 and blood return line 92.

[0092] For example Figure 3bAs shown, when the target treatment mode input by the user is: plasma exchange (PE), the target functional device corresponding to plasma exchange (PE) is the plasma separator 62. The target pumps are: blood pump 2, fourth flow pump 14 and first flow pump 11. The target connecting pipelines are: blood extraction line 91, blood return line 92, first replacement line 81 and second replacement line 82. The second replacement line 82 is used to pump the plasma in the liquid storage bag into the blood return line 92. The first replacement line 81 and the fourth flow pump 14 are used to transport the waste liquid generated by the plasma separator 62 to the waste liquid bag.

[0093] For example Figure 3c As shown, when the target treatment mode input by the user is: plasma adsorption (PA), the target functional device corresponding to plasma adsorption (PA) is the plasma separator 62 and the adsorber 63. The target pumps are: the blood pump 2 and the first flow pump 11. The target connecting pipelines are: the blood extraction pipeline 91, the blood return pipeline 92, the first adsorption pipeline 71 and the second adsorption pipeline 72. Among them, the first adsorption pipeline 71 is connected between the liquid outlet of the plasma separator 62 and one end of the adsorber 63, and the second adsorption pipeline 72 is connected between the blood return pipeline 92 and the other end of the adsorber 63.

[0094] For example, Figure 8 As shown in the figure, when the target treatment mode input by the user is: continuous venovenous hemofiltration post-dilution (CVVH-Post), the treatment data of continuous venovenous hemofiltration post-dilution (CVVH-Post) are: treatment time more than 24h, blood pump flow rate is 50-200ml / min, renal dose is: 20-25ml / (kg*h), ultrafiltration flow rate is: renal dose*patient weight, replacement fluid flow rate is: 1500-2000ml / h, and there is no dialysate. Then the target functional device in the target pipeline assembly corresponding to the target treatment mode is the dialyzer 61, and the target pumps are: blood pump 2, fourth flow pump 14, first flow pump 11; the target connecting pipelines are: blood extraction pipeline 91, blood return blood pipeline 92, the first CRRT pipeline 93 connecting the liquid storage bag and the first flow pump 11, the second CRRT pipeline 94 connected between the first CRRT pipeline 93 and the blood return blood pipeline 92, and the fourth CRRT pipeline 96 connected to the liquid inlet of the dialyzer 61 and the waste liquid bag.

[0095] After the target pipeline assembly is determined, the pipeline diagram corresponding to the target pipeline assembly can be displayed on the display operation screen, that is, the pipeline diagram shown in Figure 3 can be displayed on the display operation screen to guide the user to assemble the target pipeline assembly according to the pipeline diagram. That is, the user can connect the target pipeline between the target pump and the target function device according to the pipeline diagram corresponding to the target pipeline assembly displayed on the display operation screen to form a corresponding liquid circuit of the target pipeline assembly.

[0096] S3: Obtaining treatment data corresponding to the target treatment mode, and calculating a target opening of the target pump according to the treatment data and performance parameters of the target pump;

[0097] After the user has completed the pipeline connection according to the target pipeline assembly, the controller can obtain the treatment data corresponding to the target treatment mode. Specifically, the treatment data of the target treatment mode can be input by the user, or the corresponding treatment data can be found in a preset database.

[0098] Once the treatment data corresponding to the target treatment mode is determined, the target opening of the target pump can be calculated based on the treatment data and the performance parameters of the target pump.

[0099] Specifically, the performance parameter of the target pump is: the corresponding relationship between the opening and the pump speed.

[0100] S4: controlling the target pump to start according to the target opening of the target pump, and controlling the connection of multiple target connecting pipelines to form a liquid circuit corresponding to the target treatment mode with the target fluid bag.

[0101] After the target opening of each target pump is determined, the target pump can be started and controlled according to the opening of the target pump, and multiple target connecting tubes can be controlled to be connected to form a liquid circuit corresponding to the target treatment mode with the target liquid bag, so that the blood drawn from the patient's body can be returned to the patient's body after treatment.

[0102] The present invention provides a control method for a blood purification treatment mode, wherein the blood purification system included in the blood purification device includes five pumps, multiple functional devices, and multiple connecting pipelines connected between the multiple pumps and between the pumps and the functional devices. By determining the target functional device, the target pump, and the target pipeline according to the target treatment mode input by the user, and calculating the target opening of the target pump according to the treatment data of the target treatment mode, and controlling the start of the target pump and the conduction of the target pipeline according to the target opening to form a liquid circuit corresponding to the target treatment mode, the patient can be treated according to the target treatment mode. By regulating the start or disconnection of the pump, the start or disconnection of the functional device, and the conduction or cutoff of multiple connecting pipelines, the liquid circuits corresponding to multiple pipeline components can be combined, and the liquid circuits corresponding to multiple pipeline components can correspond to multiple treatment modes, thereby realizing the integration of more treatment modes on a blood purification device, improving the integration and convenience of use of the blood purification device.

[0103] In one embodiment of the present invention, the blood purification system includes a plurality of blood treatment components, and the plurality of blood treatment components correspond one to one to a plurality of treatment types, for example Figure 1 The type of treatment for the blood treatment component shown is CRRT treatment. Figure 4As shown, S2 (determining a target pipeline component matching the target treatment mode according to the target treatment mode) may include the following steps:

[0104] S21: determining, according to the target treatment mode, a target treatment type corresponding to the target treatment mode from among multiple treatment types;

[0105] The treatment type corresponding to each treatment mode can be stored in a preset database. Then, when the user inputs the target treatment mode, the controller can match the target treatment mode in the preset database to determine the target treatment type corresponding to the target treatment mode.

[0106] For example, if the target treatment mode input by the user is: continuous venovenous hemofiltration post-dilution (CVVH-post), then the corresponding target treatment type is CRRT treatment.

[0107] S22: determining a target blood treatment component corresponding to the target treatment type from among a plurality of blood treatment components according to the target treatment type;

[0108] After the target treatment type of the target treatment mode is determined, the target treatment type can be determined to select a corresponding target blood treatment component from multiple blood treatment components. For example, when the treatment type of the target treatment mode is CRRT treatment, the target blood treatment component corresponding to CRRT treatment can be determined, that is, Figure 1 Blood treatment components shown.

[0109] After the target blood treatment component is determined, the target blood treatment component is displayed on the display operation screen. The user can manually connect the corresponding pump, functional device and connecting pipeline according to the pipeline diagram of the target blood treatment component displayed on the display operation screen to form the corresponding pipeline of the target blood treatment component.

[0110] S23: Determine, in the target blood treatment component according to the treatment data of the target treatment mode, a target functional device, a target pump, and a target connecting pipeline corresponding to the target treatment mode.

[0111] By selecting the corresponding target function device and target pump in the target blood treatment component, the corresponding target pump can be selected more quickly.

[0112] Specifically, the specific method for determining the target functional device and the target pump in the target blood treatment component according to the target treatment mode may be:

[0113] The target function device is determined according to the treatment data corresponding to the target treatment mode, and then the target pump is determined according to the target function device.

[0114] For example, the target treatment mode input by the user is slow continuous ultrafiltration (SCUF), and its corresponding target blood treatment component is the blood treatment component corresponding to CRRT treatment (such as Figure 1 The treatment data of SCUF is as follows: the treatment time is at least 24 hours, the blood pump flow is 50-100ml / min, the renal volume is 20-25ml / (kg*h), the ultrafiltration flow is 2-5ml / min, the total ultrafiltration volume does not exceed 4L, no replacement fluid, no dialysate. The treatment data of SCUF does not require replacement fluid or dialysate, only dialysis is needed, so it can be done in Figure 1 In the target blood treatment component shown, the target treatment device is determined to be a dialyzer, and the target pump is a pump that can pump out the waste liquid after dialyzation, so the fourth flow pump can be determined to be the target pump.

[0115] S24: Determine a target connecting line in a target blood treatment component according to the target functional device and the target pump.

[0116] After the target pump and the target function device are selected, the target connecting pipeline can be determined according to the target pump and the target function device.

[0117] For example, when the target therapy mode entered by the user is slow continuous ultrafiltration (SCUF), Figure 1 In the blood treatment component shown, the dialyzer is directly determined as the target functional device, and the fourth flow pump 14 is the target pump. In the target blood treatment component, the fourth CRRT pipeline 96 is directly determined as the target connecting pipeline.

[0118] When the patient changes the target treatment mode and the treatment type of the changed target treatment mode is still the same treatment mode, there is no need to manually reassemble the pump, connecting pipes, and functional devices. The corresponding pump, functional device, and connecting pipe can be directly selected according to the changed target treatment mode, and the corresponding pump and functional device can be directly controlled to start and the corresponding connecting pipe can be controlled to be connected. At the same time, the pumps that are not related to the changed target treatment mode can be turned off and the connecting pipes that are not related can be cut off.

[0119] In one embodiment of the present invention, in addition to the pump, functional device and connecting pipelines described above, the blood purification system also includes a pipeline selection valve, which has at least two valve ports, each of which is connected to a connecting pipeline, that is, two or more connecting pipelines can be connected through the pipeline selection valve, and the connection between the two connecting pipelines can be connected or disconnected by controlling the opening or closing of the pipeline selection valve. For example, the blood treatment components (such as Figure 1The first pipeline selection valve 51 includes two pipeline selection valves, namely the first pipeline selection valve 51 and the second pipeline selection valve 52. The three valve ports of the first pipeline selection valve 51 are respectively connected to the first CRRT pipeline 93, the second CRRT pipeline 94 and the sixth CRRT pipeline 98. The three valve ports of the second pipeline selection valve 52 are respectively connected to the third CRRT pipeline 95, the seventh CRRT pipeline 99 and the fifth CRRT pipeline 97. By controlling the opening or closing of the three valve ports of the first pipeline selection valve 51, the first CRRT pipeline 93 and the second CRRT pipeline 94, the second CRRT pipeline 94 and the sixth CRRT pipeline 98, and the first CRRT pipeline 93 and the sixth CRRT pipeline 98 are connected or cut off. The third CRRT pipeline 95 and the seventh CRRT pipeline 99 , the seventh CRRT pipeline 99 and the fifth CRRT pipeline 97 , and the third CRRT pipeline 95 and the fifth CRRT pipeline 97 are connected or blocked by controlling the opening or closing of the three valve ports of the second pipeline selection valve 52 .

[0120] By setting a pipeline selection valve, the entire blood purification system can use fewer pumps to form more liquid circuits to accommodate more treatment modes.

[0121] When the blood purification system includes a pipeline selection valve, when controlling the conduction of the target pipeline, it is necessary to control the pipeline selection valve to conduct the target pipeline, that is, Figure 5 As shown, S4 (controlling the start of the target pump according to the target opening of each target pump to control the conduction of multiple target connecting pipelines) specifically includes the following steps:

[0122] S41: Determine the target pipeline selection valve according to the target connection pipeline;

[0123] After the target connecting tube is determined, if the target connecting tube is connected to a tube selection valve, then the target tube selection valve corresponding to the target connecting tube is determined. For example, when the target treatment mode input by the user is continuous venovenous hemodialysis (CVVHD), the blood treatment component (such as Figure 1 After the blood extraction line 91, the blood return line 92, the fourth CRRT line 96, and the second CRRT line 94 are determined as target connection lines, the first line selection valve 51 on the second CRRT line 94 can be determined as the target line selection valve.

[0124] S42: Control the target pipeline selection valve to conduct the target connecting pipeline, and control the target pipeline selection valve to cut off the reference connecting pipeline, where the reference connecting pipeline is a connecting pipeline other than the target connecting pipeline among the multiple connecting pipelines correspondingly connected to the target pipeline selection valve;

[0125] When the target pipeline selection valve is determined, the target pipeline selection valve can be controlled to conduct the target connecting pipeline and simultaneously cut off other connecting pipelines except the target connecting pipeline.

[0126] For example, the target treatment mode input by the user is continuous venovenous hemodialysis (CVVHD), and it is determined that: the target pump is the dialyzer 61; the target connecting pipelines are: the blood withdrawal line 91, the blood return line 92, the fourth CRRT line 96, the second CRRT line 94 and the first CRRT line 93; and the target pipeline selection valve is the first pipeline selection valve 51.

[0127] The first pipeline selection valve 51 can be controlled to cut off the second CRRT pipeline 94 and the sixth CRRT pipeline 97, and connect the second CRRT pipeline 94 and the first CRRT pipeline 93; at the same time, the second pipeline selection valve 52 does not start working.

[0128] S43: Controlling the start of multiple target pumps according to the target opening degree of each target pump.

[0129] The target treatment mode input by the user is continuous venovenous hemodialysis (CVVHD), and the blood pump 2, the fourth flow pump 14 and the first flow pump 11 are determined as the target pumps. Therefore, the blood pump 2, the fourth flow pump 14 and the first flow pump 11 are controlled to be turned on. The pipeline diagram of the target pipeline assembly of continuous venovenous hemodialysis (CVVHD) is as follows: Figure 6 shown.

[0130] In order to better understand the present invention, the present invention is described in detail below by taking specific embodiments as examples. The treatment type of the treatment mode corresponding to Embodiments 1 to 9 is CRRT treatment, and the blood treatment component corresponding to CRRT treatment is a CRRT treatment component, such as Figure 1 shown.

[0131] Example 1: Target treatment mode: Continuous venovenous hemofiltration predilution (CVVH-pre)

[0132] Continuous venovenous hemofiltration pre-dilution (CVVH-pre): Before hemodialysis, the blood is diluted with replacement fluid. The corresponding treatment data are: treatment time: more than 24 hours, blood pump flow: 50-200ml / min, kidney dose: 20-25ml / (kg*h), replacement fluid flow: 1500-2000ml / l.

[0133] The control method of the blood purification treatment mode includes the following steps:

[0134] S101: determining that the treatment type of the target treatment mode is CRRT treatment, and determining that the corresponding target treatment type is CRRT treatment from among multiple treatment types according to CRRT treatment, and determining that the corresponding target blood treatment component is CRRT treatment component from among multiple blood treatment components according to CRRT treatment;

[0135] S102: according to the treatment data of continuous venovenous hemofiltration pre-dilution (CVVH-pre), the dialyzer 61 is determined as the target functional device, the blood pump 2, the third flow pump 13, the fourth flow pump 14 and the first flow pump 11 are determined as the target pumps, and the third CRRT pipeline 95, the first CRRT pipeline 93, the fourth CRRT pipeline 96, the blood extraction pipeline 91 and the blood return pipeline 92 are determined as the target connecting pipelines;

[0136] S103: Determine the opening of the blood pump 2, the opening of the third flow pump 13, the opening of the fourth flow pump 14 and the opening of the first flow pump 11 according to the treatment data of the continuous venovenous hemofiltration pre-dilution (CVVH-pre);

[0137] The opening degree of the blood pump 2 is calculated based on the blood pump flow rate (50-200 ml / min) in the treatment data and the performance parameters of the blood pump 2.

[0138] The opening degrees of the first flow pump 11 and the third flow pump 13 are calculated according to the replacement fluid flow rate (1500-2000 ml / l) in the treatment data.

[0139] The opening degree of the fourth flow pump 14 is the opening degree when the waste liquid in the dialyzer 61 is pumped out.

[0140] S104: Control the blood pump to start to open the blood extraction line, control the first flow pump 11 to open the first CRRT line, control the fourth flow pump 14 to open so that the fourth CRRT line is connected to the discharge port of the dialyzer 61; control the third flow pump 13 to connect the third CRRT line 95 to the first CRRT line 93.

[0141] S105: Control all other devices in the CRRT treatment component except the target pump to stop working, so as to cut off the other connecting pipelines in the CRRT treatment component except the target connecting pipeline. For example, control the second flow pump 12, the first pipeline selection valve 51 and the second pipeline selection valve 52 to stop working, cut off the first CRRT pipeline 93 and the second CRRT pipeline 94, and cut off the first CRRT pipeline 93 and the seventh CRRT pipeline 99. After S101 to S105, the liquid circuit of the continuous venovenous hemofiltration pre-dilution (CVVH-pre) is as follows Figure 7 shown.

[0142] Example 2: Target treatment mode: continuous venovenous hemofiltration postdilution (CVVH-post)

[0143] Continuous venovenous hemofiltration postdilution (CVVH-post): After hemodialysis, the blood is diluted with replacement fluid. The corresponding treatment data are: treatment time: more than 24 hours, blood pump flow: 50-200ml / min, kidney dose: 20-25ml / (kg*h), replacement fluid flow: 1500-2000ml / l.

[0144] The control method of the blood purification treatment mode includes the following steps:

[0145] S201: determining that the treatment type of the target treatment mode is CRRT treatment, and determining that the corresponding target treatment type is CRRT treatment from among multiple treatment types according to CRRT treatment, and determining that the corresponding target blood treatment component is CRRT treatment component from among multiple blood treatment components according to CRRT treatment;

[0146] S202: Determine the dialyzer 61 as the target functional device according to the treatment data of continuous venovenous hemofiltration post-dilution (CVVH-post), determine the blood pump 2, the fourth flow pump 14, the second flow pump 12 and the first flow pump 11 as the target pumps, and determine the second CRRT pipeline 94, the fourth CRRT pipeline 96, the blood extraction pipeline 91 and the blood return pipeline 92 as the target connecting pipelines;

[0147] S203: Determine the opening of the blood pump 2, the opening of the fourth flow pump 14, and the opening of the first flow pump 11 according to the treatment data of continuous venovenous hemofiltration post-dilution (CVVH-post);

[0148] The opening degree of the blood pump 2 is calculated based on the blood pump flow rate (50-200 ml / min) in the treatment data and the performance parameters of the blood pump 2.

[0149] The opening degrees of the first flow pump 11 and the second flow pump 12 are calculated according to the replacement fluid flow rate (1500-2000 ml / l) in the treatment data, the performance parameters of the first flow pump 11 and the performance parameters of the second flow pump 12.

[0150] The opening degree of the fourth flow pump 14 is the opening degree when the waste liquid in the dialyzer 61 is pumped out.

[0151] S204: Control the blood pump 2 to start to connect the blood extraction line 91; control the first flow pump 11 to start to connect the first CRRT line 93 and the replacement fluid storage bag; control two valve ports of the first line selection valve to open and the second flow pump 12 to start to connect the first CRRT line 93 and the second CRRT line 94 and cut off the first CRRT line 93 and the sixth CRRT line 98; control the fourth flow pump 14 to start so that the fourth CRRT line 96 is connected to the discharge port of the dialyzer 61; S105: Control all other devices in the CRRT treatment component except the target pump to stop working to cut off the other connecting lines in the CRRT treatment component except the target connecting line. For example, the third flow pump 13 and the second pipeline selection valve 52 are controlled to stop working, the first CRRT pipeline 93 and the third CRRT pipeline 95 are cut off, the first CRRT pipeline 93 and the fifth CRRT pipeline 97 are cut off, the first CRRT pipeline 93 and the seventh CRRT pipeline 99 are cut off, and the fifth CRRT pipeline 97 and the seventh CRRT pipeline 99 are cut off.

[0152] After S201 to S205, the fluid circuit of the continuous venovenous hemofiltration post-dilution (CVVH-post) is as follows: Figure 8 shown.

[0153] Example 3: Target treatment mode: Continuous venovenous hemofiltration pre-post mixed dilution (CVVH-Mix)

[0154] Continuous venovenous hemofiltration pre-post mixed dilution (CVVH-Mix): Before and after hemodialysis, replacement fluid is used to dilute the blood. The corresponding treatment data are: treatment time: more than 24 hours, blood pump flow: 50-200ml / min, kidney dose: 20-25ml / (kg*h), pre-replacement fluid flow: 1500-2000ml / l, post-replacement fluid flow: 1500-2000ml / l.

[0155] The control method of the blood purification treatment mode includes the following steps:

[0156] S301: determining that the treatment type of the target treatment mode is CRRT treatment, and determining that the corresponding target treatment type is CRRT treatment from among multiple treatment types according to CRRT treatment, and determining that the corresponding target blood treatment component is CRRT treatment component from among multiple blood treatment components according to CRRT treatment;

[0157] S302: according to the treatment data of continuous venovenous hemofiltration pre-post mixed dilution (CVVH-Mix), the dialyzer 61 is determined as the target functional device, the blood pump 2, the fourth flow pump 14, the second flow pump 12 and the first flow pump 11 are determined as the target pumps, the second CRRT pipeline 94, the first CRRT pipeline 93, the second CRRT pipeline 94, the third CRRT pipeline 95, the fourth CRRT pipeline 96, the blood withdrawal pipeline 91 and the blood return pipeline 92 are determined as the target connecting pipelines, and the first pipeline selection valve 51 and the second pipeline selection valve 52 are determined as the target pipeline selection valves;

[0158] S303: The treatment data of continuous venovenous hemofiltration pre-post mixed dilution (CVVH-Mix) determines the opening degree of the blood pump 2, the first flow pump 11, the second flow pump 12, and the fourth flow pump 14;

[0159] The opening degree of the blood pump 2 is calculated based on the blood pump flow rate (50-200 ml / min) in the treatment data and the performance parameters of the blood pump 2.

[0160] The opening of the first flow pump 11 is calculated based on the sum of the front replacement fluid flow (1500-2000ml / l) and the rear replacement fluid flow (1500-2000ml / l) in the treatment data and the performance parameters of the first flow pump. The opening of the second flow pump 12 is calculated based on the rear replacement fluid flow (1500-2000ml / l) and the performance parameters of the second flow pump 12.

[0161] The opening degree of the fourth flow pump 14 is the opening degree when the waste liquid in the dialyzer 61 is pumped out.

[0162] S304: Control the blood pump 2 to start to connect the blood extraction line 91; control the first flow pump 11 to start to connect the replacement fluid storage bag and the first CRRT line 93; control the second flow pump 12 to start and two valve ports of the first line selection valve 51 to open to connect the first CRRT line 93 and the second CRRT line 94, and cut off the first CRRT line 93 and the sixth CRRT line 98;

[0163] The fourth flow pump 14 is controlled to start so that the fourth CRRT pipeline 96 is connected to the discharge port of the dialyzer 61; two valve ports of the second pipeline selection valve 52 are controlled to open to connect the first CRRT pipeline 93 and the seventh CRRT pipeline 99 and cut off the seventh CRRT pipeline 99 and the fifth CRRT pipeline 97.

[0164] S305: Control all components except the target pump in the CRRT treatment component to stop working, so as to cut off the other connecting pipelines except the target connecting pipeline in the CRRT treatment component. For example, control the third flow pump 13 to stop working, so as to cut off the first CRRT pipeline 93 and the third CRRT pipeline 95.

[0165] After S301 to S305, the liquid circuit of the continuous venovenous hemofiltration pre-post mixed dilution (CVVH-Mix) is as follows: Fig. 9 shown.

[0166] Example 4: Target treatment mode: continuous venovenous hemodiafiltration pre-dilution (CVVHDF-pre)

[0167] Continuous venovenous hemodiafiltration pre-dilution (CVVHDF-pre): The corresponding treatment data are: treatment time: more than 24 hours, blood pump flow: 50-200ml / min, kidney dose: 20-25ml / (kg*h), replacement fluid flow: 1000-1500ml / l, dialysate flow: 1000-1500ml / l.

[0168] The control method of the blood purification treatment mode includes the following steps:

[0169] S401: determining that the treatment type of the target treatment mode is CRRT treatment, and determining that the corresponding target treatment type is CRRT treatment from among multiple treatment types according to CRRT treatment, and determining that the corresponding target blood treatment component is CRRT treatment component from among multiple blood treatment components according to CRRT treatment;

[0170] S402: according to the treatment data of continuous venovenous hemodiafiltration pre-dilution (CVVHDF-pre), the dialyzer 61 is determined as the target functional device, the blood pump 2, the fourth flow pump 14, the third flow pump 13 and the first flow pump 11 are determined as the target pumps, the first CRRT pipeline 93, the fifth CRRT pipeline 97, the third CRRT pipeline 95, the fourth CRRT pipeline 96, the blood withdrawal pipeline 91 and the blood return pipeline 92 are determined as the target connecting pipelines, and the second pipeline selection valve 52 is determined as the target pipeline selection valve;

[0171] S403: Determine the opening of the blood pump 2, the first flow pump 11, the third flow pump 13, and the fourth flow pump 14 according to the treatment data of the continuous venovenous hemodiafiltration pre-dilution (CVVHDF-pre);

[0172] The opening degree of the blood pump 2 is calculated based on the blood pump flow rate (50-200 ml / min) in the treatment data and the performance parameters of the blood pump 2.

[0173] The opening of the first flow pump 11 is calculated according to the replacement fluid flow (1000-1500 ml / l) in the treatment data and the performance parameters of the first flow pump, and the opening of the third flow pump 13 is calculated according to the dialysate flow: 1000-1500 ml / l and the performance parameters of the third flow pump 13.

[0174] The opening degree of the fourth flow pump 14 is the opening degree when the waste liquid in the dialyzer 61 is pumped out.

[0175] S404: Control the blood pump 2 to start to connect the blood extraction line 91; control the first flow pump 11 and the third flow pump 13 to start and control two valve ports of the second line selection valve 52 to open to connect the first CRRT line 93 and the third CRRT line 95, connect the first CRRT line 93 and the fifth CRRT line 97, and cut off the first CRRT line 93 and the seventh CRRT line 99;

[0176] The fourth flow pump 14 is controlled to start so that the fourth CRRT line 96 is connected to the drain port of the dialyzer 61 .

[0177] S405: Control all other devices in the CRRT treatment component except the target pump to stop working, so as to cut off the other connecting pipelines in the CRRT treatment component except the target connecting pipeline. For example, control the second flow pump 12 to stop working, control the first pipeline selection valve 51 to stop working (that is, all three valve ports are closed), so as to cut off the first CRRT pipeline 93 and the second CRRT pipeline 94, and cut off the first CRRT pipeline 93 and the sixth CRRT pipeline 98.

[0178] After S401 to S405, the liquid circuit of the continuous venovenous hemodiafiltration pre-dilution (CVVHDF-pre) is as follows: Fig.10 shown.

[0179] Example 5: Target treatment mode: continuous venovenous hemodiafiltration post-dilution (CVVHDF-post)

[0180] Continuous venovenous hemodiafiltration post-dilution (CVVHDF-post): The corresponding treatment data are: treatment time: more than 24 hours, blood pump flow: 50-200ml / min, kidney dose: 20-25ml / (kg*h), replacement fluid flow: 1000-1500ml / l, dialysate flow: 1000-1500ml / l.

[0181] The control method of the blood purification treatment mode includes the following steps:

[0182] S501: Determine that the treatment type of the target treatment mode is CRRT treatment, and determine that the corresponding target treatment type is CRRT treatment from among multiple treatment types according to CRRT treatment, and determine that the corresponding target blood treatment component is CRRT treatment component from among multiple blood treatment components according to CRRT treatment;

[0183] S502: according to the treatment data of continuous venovenous hemodiafiltration post-dilution (CVVHDF-post), the dialyzer 61 is determined as the target functional device, the blood pump 2, the fourth flow pump 14, the second flow pump 12 and the first flow pump 11 are determined as the target pumps, the first CRRT pipeline 93, the fifth CRRT pipeline 97, the second CRRT pipeline 94, the fourth CRRT pipeline 96, the blood withdrawal pipeline 91 and the blood return pipeline 92 are determined as the target connecting pipelines, and the first pipeline selection valve 51 and the second pipeline selection valve 52 are determined as the target pipeline selection valves;

[0184] S503: Determine the opening degree of the blood pump 2, the first flow pump 11, the second flow pump 12, and the fourth flow pump 14 based on the treatment data of continuous venovenous hemodiafiltration post-dilution (CVVHDF-post);

[0185] The opening degree of the blood pump 2 is calculated based on the blood pump flow rate (50-200 ml / min) in the treatment data and the performance parameters of the blood pump 2.

[0186] The opening of the first flow pump 11 is calculated based on the sum of the replacement fluid flow rate (1000-1500ml / l) and the dialysate flow rate: 1000-1500ml / l in the treatment data, and the performance parameters of the first flow pump. The opening of the second flow pump 12 is calculated based on the replacement fluid flow rate (1000-1500ml / l) and the performance parameters of the second flow pump 12.

[0187] The opening degree of the fourth flow pump 14 is the opening degree when the waste liquid in the dialyzer 61 is pumped out.

[0188] S504: Control the blood pump 2 to start to connect the blood extraction line 91; control the first flow pump 11 and the second flow pump 12 to start and control two valve ports of the first line selection valve 51 to open to connect the first CRRT line 93 and the second CRRT line 94, and cut off the first CRRT line 93 and the sixth CRRT line 98. Control two valve ports of the second line selection valve 52 to open to connect the first CRRT line 93 and the fifth CRRT line 97 and cut off the first CRRT line 93 and the seventh CRRT line 99.

[0189] The fourth flow pump 14 is controlled to start so that the fourth CRRT pipeline 96 is connected to the drain port of the dialyzer 61 .

[0190] S505: Control all other components in the CRRT treatment component except the target pump to stop working, so as to cut off the other connecting pipelines in the CRRT treatment component except the target connecting pipeline. For example, control the third flow pump 13 to be turned off, that is, do not start the third flow pump 13, so as to cut off the first CRRT pipeline 93 and the third CRRT pipeline 95.

[0191] After S501 to S505, the liquid circuit of continuous venovenous hemodiafiltration post-dilution (CVVHDF-post) is as follows Fig.11 shown.

[0192] Example 6: Target treatment mode: continuous venovenous hemodialysis (CVVHD)

[0193] Continuous venovenous hemodialysis (CVVHD): The corresponding treatment data are: treatment time: more than 24 hours, blood pump flow: 50-200ml / min, kidney dose: 20-25ml / (kg*h), dialysate flow: 1000-1500ml / l.

[0194] The control method of the blood purification treatment mode includes the following steps:

[0195] S601: Determine that the treatment type of the target treatment mode is CRRT treatment, and determine that the corresponding target treatment type is CRRT treatment from among multiple treatment types according to CRRT treatment, and determine that the corresponding target blood treatment component is CRRT treatment component from among multiple blood treatment components according to CRRT treatment;

[0196] S602: Determine the dialyzer 61 as the target functional device according to the treatment data of continuous venovenous hemodialysis (CVVHD), determine the blood pump 2, the fourth flow pump 14 and the first flow pump 11 as the target pumps, determine the first CRRT pipeline 93, the fifth CRRT pipeline 97, the fourth CRRT pipeline 96, the blood withdrawal pipeline 91 and the blood return pipeline 92 as the target connecting pipelines, and determine the second pipeline selection valve 52 as the target pipeline selection valve;

[0197] S603: Determine the opening degree of the blood pump 2, the first flow pump 11, and the fourth flow pump 14 based on the treatment data of continuous venovenous hemodialysis (CVVHD);

[0198] The opening degree of the blood pump 2 is calculated based on the blood pump flow rate (50-200 ml / min) in the treatment data and the performance parameters of the blood pump 2.

[0199] The opening degree of the first flow pump 11 is calculated according to the dialysate flow rate (1000-1500 ml / l) in the treatment data, the performance parameters of the first flow pump 11 and the second flow pump 12 .

[0200] The opening degree of the fourth flow pump 14 is the opening degree when the waste liquid in the dialyzer 61 is pumped out.

[0201] S604: Control the blood pump 2 to start to connect the blood extraction line 91; control the first flow pump 11 to start to connect the dialysate storage bag and the first CRRT line 93; control the two valve ports of the second line selection valve 52 to open, so as to connect the first CRRT line 93 and the fifth CRRT line 97, and cut off the first CRRT line 93 and the seventh CRRT line 99.

[0202] Control the fourth flow pump 14 to start so that the fourth CRRT pipeline 96 is connected to the discharge port of the dialyzer 61;

[0203] S605: Control all other devices in the CRRT treatment component except the target pump to stop working, so as to cut off the other connecting pipelines in the CRRT treatment component except the target connecting pipeline. For example, control the second flow pump 12 and the third flow pump 13 to stop working, so as to cut off the first CRRT pipeline 93 and the second CRRT pipeline 94, and cut off the first CRRT pipeline 93 and the fifth CRRT pipeline 95; control the three valve ports of the first pipeline selection valve 51 to be closed, so as to cut off the first CRRT pipeline 93 and the sixth CRRT pipeline 98, and cut off the sixth CRRT pipeline 98 and the second CRRT pipeline 94. .

[0204] After S601 to S605, the fluid circuit of continuous venovenous hemodialysis (CVVHD) is as follows: Figure 6 shown.

[0205] Example 7: Target treatment mode: continuous venovenous hemodiafiltration pre-post mixed dilution (CVVHDF-Mix)

[0206] Continuous venovenous hemodiafiltration pre-post mixed dilution (CVVHDF-Mix): After hemodialysis, the blood is diluted with replacement fluid. The corresponding treatment data are: treatment time: more than 24 hours, blood pump flow: 50-200ml / min, kidney dose: 20-25ml / (kg*h), replacement fluid flow: 1000-1500ml / l, dialysate flow: 1000-1500ml / l.

[0207] The control method of the blood purification treatment mode includes the following steps:

[0208] S701: Determine that the treatment type of the target treatment mode is CRRT treatment, and determine that the corresponding target treatment type is CRRT treatment from among multiple treatment types according to CRRT treatment, and determine that the corresponding target blood treatment component is CRRT treatment component from among multiple blood treatment components according to CRRT treatment;

[0209] S702: The treatment data of continuous venovenous hemodiafiltration pre-post mixed dilution (CVVHDF-Mix) determines the dialyzer 61 as the target functional device, determines the blood pump 2, the third flow pump 13, the fourth flow pump 14, the second flow pump 12 and the first flow pump 11 as the target pumps, determines the first CRRT pipeline 93, the third CRRT pipeline 95, the fifth CRRT pipeline 97, the second CRRT pipeline 94, the fourth CRRT pipeline 96, the blood withdrawal pipeline 91 and the blood return pipeline 92 as the target connecting pipelines, and determines the first pipeline selection valve 51 and the second pipeline selection valve 52 as the target pipeline selection valves;

[0210] S703: Determine the opening of the blood pump 2, the first flow pump 11, the second flow pump 12, the third flow pump 13, and the fourth flow pump 14 according to the treatment data of the continuous venovenous hemodiafiltration pre-post mixed dilution (CVVHDF-Mix);

[0211] The opening degree of the blood pump 2 is calculated based on the blood pump flow rate (50-200 ml / min) in the treatment data and the performance parameters of the blood pump 2.

[0212] The opening of the first flow pump 11 is calculated according to the sum of the replacement fluid flow (1000-1500ml / l) and the dialysate flow: 1000-1500ml / l in the treatment data and the performance parameters of the first flow pump 11; the opening of the second flow pump 12 is calculated according to the replacement fluid flow (1000-1500ml / l) and the performance parameters of the second flow pump 12; the opening of the third flow pump 13 is calculated according to the dialysate flow: 1000-1500ml / l and the performance parameters of the third flow pump 13.

[0213] The opening degree of the fourth flow pump 14 is the opening degree when the waste liquid in the dialyzer 61 is pumped out.

[0214] S704: Control the blood pump 2 to start to connect the blood extraction line 91; control the first flow pump 11 and the third flow pump 13 to start and control two valve ports of the second pipeline selection valve 52 to open to connect the first CRRT pipeline 93 and the third CRRT pipeline 95, connect the first CRRT pipeline 93 and the fifth CRRT pipeline 97, and cut off the fifth CRRT pipeline 97 and the seventh CRRT pipeline 99; control the second flow pump 12 to start and control two valve ports in the first pipeline selection valve 51 to connect the first CRRT pipeline 93 and the fourth CRRT pipeline 94, and cut off the first CRRT pipeline 93 and the sixth CRRT pipeline 98;

[0215] Control the fourth flow pump 14 to start so that the fourth CRRT pipeline 96 is connected to the discharge port of the dialyzer 61;

[0216] S705: Control all other devices in the CRRT treatment component except the target pump to stop working, so as to cut off the other connecting pipelines in the CRRT treatment component except the target connecting pipeline.

[0217] After S701 to S705, the liquid circuit of the continuous venovenous hemodiafiltration pre-post-mix dilution (CVVHDF-Mix) is as follows: Fig.12 shown.

[0218] Example 8: Target treatment mode: slow continuous ultrafiltration (SCUF)

[0219] Slow continuous ultrafiltration (SCUF): The corresponding treatment data are: treatment time is at least 24 hours, blood pump flow is 50-100ml / min, renal volume is 20-25ml / (kg*h), ultrafiltration flow is 2-5ml / min, the total ultrafiltration volume does not exceed 4L at one time, there is no replacement fluid and no dialysate.

[0220] The control method of the blood purification treatment mode includes the following steps:

[0221] S801: Determine that the treatment type of the target treatment mode is CRRT treatment, and determine that the corresponding target treatment type is CRRT treatment from among multiple treatment types according to CRRT treatment, and determine that the corresponding target blood treatment component is CRRT treatment component from among multiple blood treatment components according to CRRT treatment;

[0222] S802: Determine the dialyzer 61 as the target functional device according to the slow continuous ultrafiltration (SCUF) treatment data, determine the blood pump 2 and the fourth flow pump 14 as the target pumps, and determine the fourth CRRT pipeline 96, the blood extraction pipeline 91 and the blood return pipeline 92 as the target connecting pipelines;

[0223] S803: Determine the opening degree of the blood pump 2 and the opening degree of the fourth flow pump 14 according to the slow continuous ultrafiltration (SCUF) treatment data;

[0224] The opening degree of the blood pump 2 is calculated based on the blood pump flow rate (50-200 ml / min) in the treatment data and the performance parameters of the blood pump 2.

[0225] The opening degree of the fourth flow pump 14 is the opening degree when the waste liquid in the dialyzer 61 is pumped out.

[0226] S804 : Control the blood pump 2 to start so as to connect the blood extraction line 91 ; control the fourth flow pump 14 to start so as to connect the fourth CRRT line 96 to the liquid discharge port of the dialyzer 61 .

[0227] S805: Control all other devices in the CRRT treatment component except the target pump to stop working, so as to cut off the other connecting pipelines in the CRRT treatment component except the target connecting pipeline. For example, control the first flow pump 11, the second flow pump 12 and the third flow pump 13 to stop working, and control the three valve ports of the first pipeline selection valve 51 and the second pipeline selection valve 52 to be closed.

[0228] After S801 to S805, the liquid circuit of slow continuous ultrafiltration (SCUF) is as follows: Fig.13 shown.

[0229] Exemplary Controller

[0230] As a third aspect of the present invention, the present invention also provides a controller for a blood purification treatment mode, such as Fig.14 As shown, the controller 100 includes:

[0231] The data acquisition module 101 is used to acquire a target treatment mode input by a user, where the target treatment mode is one or more treatment modes among a plurality of preset treatment modes;

[0232] A first determination module 102 is used to determine a target pipeline component that matches the target treatment mode according to the target treatment mode, the target pipeline component including: a target function device, a target pump, and a plurality of target connecting pipelines;

[0233] A calculation module 103, used to obtain treatment data corresponding to the target treatment mode, and calculate the target opening degree of each target pump according to the treatment data and the performance parameters of the multiple target pumps;

[0234] The control module 104 is used to control the start-up of the target pump according to the target opening of the target pump, so as to control the conduction of multiple target connecting pipelines to form a liquid circuit corresponding to the target treatment mode.

[0235] Exemplary blood purification system

[0236] As a fourth aspect of the present invention, the present invention also provides a blood purification system, comprising the blood purification equipment described above, at least one functional device, a liquid storage bag storing a target liquid, and a plurality of connecting pipes connected between a pump and the functional device.

[0237] Through the control method of the treatment mode described above, the corresponding functional device, the target liquid storage bag storing the target liquid and the target device in the blood purification equipment (such as a target pump, a target pipeline selection valve, etc.) are selected according to the target treatment mode, and the corresponding target connecting pipeline is selected according to the target device to form the liquid pipeline corresponding to the target treatment mode.

[0238] Specifically, the blood purification system may include a plurality of blood treatment components corresponding to a plurality of treatment types. For example, when the treatment type is CRRT treatment, the corresponding blood treatment component is a CRRT treatment component, such as Figure 1 shown.

[0239] When the treatment type is CRRT treatment, the corresponding functional device is a dialyzer and / or filter;

[0240] When the treatment type is plasma therapy, the corresponding functional device is any one or more combinations of a plasma separator, a plasma component separator, and a plasma adsorber;

[0241] When the treatment type is blood perfusion, the corresponding functional device is a perfusion device.

[0242] Exemplary Electronic Devices

[0243] Fig.15 The figure shows a structural block diagram of an electronic device according to an embodiment of the present invention.

[0244] like Fig.15 As shown, the electronic device 200 includes one or more processors 201 and a memory 202 .

[0245] The processor 201 may be a central processing unit (CPU) or other forms of processing units having data processing capabilities and / or instruction execution capabilities, and may control other components in the electronic device 200 to perform desired functions.

[0246] The memory 202 may include one or more computer program products, which may include various forms of computer-readable storage media, such as volatile memory and / or non-volatile memory. The volatile memory may include, for example, random access memory (RAM) and / or cache memory (cache), etc. The non-volatile memory may include, for example, read-only memory (ROM), hard disk, flash memory, etc. One or more computer program instructions may be stored on the computer-readable storage medium, and the processor 201 may run the program instructions to implement a control method for a blood purification treatment mode of each embodiment of the present invention described above and / or other desired functions. Various contents such as input signals, signal components, noise components, etc. may also be stored in the computer-readable storage medium.

[0247] In one example, the electronic device 200 may further include: an input device 203 and an output device 204 , and these components are interconnected via a bus system and / or other forms of connection mechanisms (not shown).

[0248] When the electronic device 200 is a stand-alone device, the input device 203 may be a communication network connector, which is used to receive the collected input signals from the first device and the second device.

[0249] In addition, the input device 203 may also include, for example, a keyboard, a mouse, and the like.

[0250] The output device 204 can output various information to the outside, including the determined distance information, direction information, etc. The output device 204 can include, for example, a display, a speaker, a printer, a communication network and a remote output device connected thereto, and the like.

[0251] Of course, to simplify, Fig.15 Only some of the components related to the present invention in the electronic device 200 are shown, and components such as a bus, an input / output interface, etc. are omitted. In addition, according to specific application conditions, the electronic device 200 may also include any other appropriate components.

[0252] The computer program product may be written in any combination of one or more programming languages ​​to write program code for performing the operations of the embodiments of the present invention, including object-oriented programming languages ​​such as Java, C++, etc., and conventional procedural programming languages ​​such as "C" or similar programming languages. The program code may be executed entirely on the user computing device, partially on the user device, as a separate software package, partially on the user computing device and partially on a remote computing device, or entirely on a remote computing device or server.

[0253] The computer readable storage medium can adopt any combination of one or more readable media. The readable medium can be a readable signal medium or a readable storage medium. The readable storage medium can include, for example, but is not limited to, a system, device or device of electricity, magnetism, light, electromagnetic, infrared, or semiconductor, or any combination of the above. More specific examples (non-exhaustive list) of readable storage media include: an electrical connection with one or more wires, a portable disk, a hard disk, a random access memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), an optical fiber, a portable compact disk read-only memory (CD-ROM), an optical storage device, a magnetic storage device, or any suitable combination of the above.

[0254] The above description has been given for the purpose of illustration and description. In addition, this description is not intended to limit the embodiments of the present invention to the forms disclosed herein. Although a number of example aspects and embodiments have been discussed above, those skilled in the art will recognize certain variations, modifications, changes, additions and sub-combinations thereof.

Claims

1. A method for controlling a blood purification treatment mode, characterized in that: Applicable to a blood purification system, the blood purification system comprising: a plurality of pumps, at least one functional device, and a plurality of connecting pipelines connected between the pumps and between the pumps and the functional device; Wherein, the control method comprises: Acquire a target treatment mode input by a user, where the target treatment mode is one or more treatment modes among a plurality of preset treatment modes; Determine a target pipeline component matching the target treatment mode according to the target treatment mode, the target pipeline component comprising: a target function device, a target pump and a plurality of target connecting pipelines; Acquiring treatment data corresponding to the target treatment mode, and calculating a target opening degree of each target pump according to the treatment data and performance parameters of the target pump; The target pump is started up according to the target opening of the target pump to control the conduction of the plurality of target connecting pipelines to form a liquid circuit corresponding to the target treatment mode.

2. The control method according to claim 1, characterized in that: The step of obtaining the target treatment mode input by the user comprises: Get the target treatment type input by the user; Determining a plurality of preset treatment modes corresponding to the target treatment type according to the target treatment type, so that the plurality of preset treatment modes are displayed on a display operation screen for a user to select a target treatment mode; Gets the target treatment mode selected by the user.

3. The control method according to claim 1 or 2, characterized in that: The blood purification system includes a plurality of blood treatment components, and the plurality of blood treatment components correspond one to one to a plurality of treatment types; Wherein, determining a target pipeline component matching the target treatment mode according to the target treatment mode includes: According to the target treatment mode, determining a target treatment type corresponding to the target treatment mode from among the multiple treatment types; According to the target treatment type, determining a target blood treatment component corresponding to the target treatment type from among the plurality of blood treatment components; According to the treatment data of the target treatment mode, a target functional device, a target pump and a target connecting pipeline corresponding to the target treatment mode are determined in the target blood treatment component.

4. The control method according to claim 3, characterized in that: The blood purification system further comprises: at least one pipeline selection valve, the pipeline selection valve having at least two valve ports, each of the valve ports being connected to one of the connecting pipelines; Wherein, the starting of the target pump is controlled according to the target opening of the target pump to control the conduction of the plurality of target connecting pipelines, including: Determining a target pipeline selection valve according to the target connecting pipeline; The target pipeline selection valve is controlled to conduct the target connecting pipeline, and the target pipeline selection valve is controlled to cut off a reference connecting pipeline, wherein the reference connecting pipeline is a connecting pipeline other than the target connecting pipeline among a plurality of connecting pipelines correspondingly connected to the target pipeline selection valve.

5. The control method according to any one of claims 1 to 4, characterized in that: The treatment types include: CRRT treatment, plasma therapy and hemoperfusion.

6. The control method according to claim 5, characterized in that: The preset treatment modes corresponding to the CRRT treatment include: continuous venovenous hemofiltration pre-dilution (CVVH-pre), continuous venovenous hemofiltration post-dilution (CVVH-post), continuous venovenous hemofiltration pre-post mixed dilution (CVVH-Mix), continuous venovenous hemodiafiltration pre-dilution (CVVHDF-pre), continuous venovenous hemodiafiltration post-dilution (CVVHDF-post), continuous venovenous hemodiafiltration pre-post mixed dilution (CVVHDF-Mix), continuous venovenous hemodialysis (CVVHD), slow continuous ultrafiltration (SCUF); The preset treatment modes corresponding to the plasma therapy include: plasma exchange (PE), double filtration plasma exchange (DFPP), paired plasma filtration adsorption (CPFA), plasma adsorption (PA), dual plasma molecular adsorption system (DPMAS), molecular adsorption recirculation system (MARS), plasma separation adsorption system (FPSA), single pass albumin dialysis (SPAD), repeated albumin dialysis (RAD), plasma filtration dialysis (PDF); The preset treatment modes corresponding to the blood perfusion include: blood perfusion (HP).

7. A controller for a blood purification treatment mode, characterized in that: include: A data acquisition module, used to acquire a target treatment mode input by a user, wherein the target treatment mode is one or more treatment modes among a plurality of preset treatment modes; A first determination module is used to determine a target pipeline component matching the target treatment mode according to the target treatment mode, wherein the target pipeline component includes: a target function device, a target pump, and a plurality of target connecting pipelines; a calculation module, used for acquiring treatment data corresponding to the target treatment mode, and calculating a target opening degree of each of the target pumps according to the treatment data and the performance parameters of the target pump; The control module is used to control the start-up of the target pump according to the target opening of the target pump, so as to control the conduction of the plurality of target connecting pipelines to form a liquid circuit corresponding to the target treatment mode.

8. A blood purification device, characterized in that: include: A plurality of pumps and a controller as claimed in claim 7; The blood purification device, at least one functional device, and a plurality of connecting pipelines connected between the pumps and between the pumps and the functional devices together constitute a blood purification system.

9. The blood purification device according to claim 8, characterized in that: The blood purification device further comprises: at least one pipeline selection valve, wherein the pipeline selection valve has at least two valve ports, and each of the valve ports is connected to one of the connecting pipelines.

10. A blood purification system, characterized in that: The blood purification system comprises: the blood purification device according to claim 8 or 9 and at least one functional device, and a plurality of connecting pipes connected between the pumps and between the pumps and the functional devices; When the treatment type is CRRT treatment, the corresponding functional device is a dialyzer and / or a filter; When the treatment type is plasma therapy, the corresponding functional device is any one or more combinations of a plasma separator, a plasma component separator, and a plasma adsorber; When the treatment type is blood perfusion, the corresponding functional device is a perfusion device.

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