Urine electrochemical detection device

Abstract

The invention discloses a urine electrochemical detection device, and belongs to the technical field of detection devices.The urine electrochemical detection device comprises an electrode kit and a buffer solution bottle, the electrode kit is detachably installed in the buffer solution bottle and comprises electrochemical test paper, a contact plate and a liquid leakage hole, and the liquid leakage hole is formed in the side edge of the electrochemical test paper; the electrochemical test paper is electrically connected with the contact plate, a buffer solution is arranged in the buffer solution bottle, the liquid leakage hole can be soaked in the buffer solution, and an electrode kit is designed to replace simple urine protein test paper, so that urine collection is more convenient, the impact force of urine can be resisted, and the electrochemical test paper is prevented from being damaged; a buffer solution bottle is designed to be matched with the electrode kit and is used for diluting the collected urine so as to meet the detection requirements; the electrode kit is inserted into the buffer bottle, and the electrochemical workstation is directly connected with the contact plate of the electrode kit for detection, so that electrochemical urine detection is conveniently and quickly performed, and home detection is facilitated.

Description

Technical Field

[0001] The present invention belongs to the technical field of detection devices, and in particular relates to a urine electrochemical detection device. Background Art

[0002] Electrochemical urine testing is a process in which urine undergoes a chemical reaction on an electrochemical reagent strip for a certain period of time, causing the electrical performance parameters of the electrochemical reagent strip to change. By detecting the change in the electrical performance parameters, the precise value of the specific component in the urine (such as urine protein) can be analyzed.

[0003] In the current new technology for measuring the concentration of new indicators using electrochemical workstations, especially for the measurement of non-enzymatic catalysts and other methods using electrochemical workstations in biological detection, it is necessary to dilute the solvent to be tested in the electrolytic cell by a certain proportion and control the pH value of the solvent to be tested.

[0004] In the electrochemical laboratory, the test is carried out with instruments such as pipettes, measuring tools, standard chemical reagents and pH meters, and it is very easy to complete; however, in home testing, simple urine protein test strips are mainly used. The sensitivity and specificity of urine protein test strips are not as good as laboratory tests, and false positive or false negative results are prone to occur. In this type of test, there is a lack of an overall convenient plan and tools, and the preparation of the test conditions cannot be completed. Summary of the invention

[0005] In order to solve the problem of lack of a convenient urine electrochemical detection device for home detection, the present invention provides a convenient urine electrochemical detection device for home detection.

[0006] The technical solution of the present invention is:

[0007] The present invention discloses a urine electrochemical detection device, which is connected to an electrochemical workstation or a portable reading instrument, and comprises an electrode kit and a buffer bottle. The electrode kit can be detachably installed in the buffer bottle. The electrode kit comprises an electrochemical test paper, a contact plate and a leakage hole. The leakage hole is arranged on the side of the electrochemical test paper. The electrochemical test paper is electrically connected to the contact plate. The buffer bottle is provided with a buffer solution, and the leakage hole can be immersed in the buffer solution.

[0008] Preferably, the electrode kit is provided with a cutting head, the buffer bottle is provided with a membrane to be penetrated, and the cutting head can puncture the membrane to be penetrated.

[0009] In another embodiment, the buffer bottle is provided with a removable cover, the inner wall of the buffer bottle or the outer wall of the electrode kit is provided with a rubber ring, the outer wall of the electrode kit is clamped in the rubber ring or the rubber ring of the outer wall of the electrode kit is clamped on the inner wall of the buffer bottle.

[0010] In another embodiment, the buffer bottle is provided with a threaded inner wall, and the electrode reagent kit is provided with an external thread, and the external thread is threadably matched with the threaded inner wall.

[0011] Furthermore, the electrode kit also includes glass fiber cotton sheets, which are arranged on both sides of the electrochemical test paper, and the leakage hole is located on the side of the glass fiber cotton sheet.

[0012] Furthermore, a via soldering needle is provided on one end of the contact plate, and the via soldering needle pierces and electrically connects the electrochemical test paper.

[0013] Furthermore, the electrochemical test paper is provided with a conductive printed layer, and the via soldering needle pierces and electrically connects the conductive printed layer.

[0014] Furthermore, a gold finger is provided on the other end of the contact plate.

[0015] Furthermore, the buffer solution bottle comprises a bottle body and a bottle cap, the membrane to be penetrated is fixedly arranged on the bottle cap, and a sealing ring is arranged between the bottle body and the bottle cap.

[0016] Furthermore, the electrode kit comprises a shell, the leakage hole is arranged on the shell, a plurality of convex columns are arranged in the shell, a circular hole is arranged on the contact plate, and the convex column passes through the circular hole.

[0017] The beneficial effects of the present invention are:

[0018] An electrode kit is designed to replace a simple urine protein test paper. The electrode kit includes an electrochemical test paper, a contact plate and a leakage hole, which makes urine collection more convenient and can resist the impact of urine to prevent damage to the electrochemical test paper. A buffer bottle is designed to cooperate with the electrode kit to dilute the collected urine to meet the detection requirements. The electrode kit is inserted into the buffer bottle, and the electrochemical workstation is directly connected to the contact plate of the electrode kit to perform detection, so that urine electrochemical detection can be performed quickly and conveniently, which is conducive to home detection. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a schematic diagram of the overall structure of a urine electrochemical detection device of the present invention;

[0020] Figure 2 It is a schematic diagram of the overall cross-sectional structure of a urine electrochemical detection device of the present invention;

[0021] Figure 3 The schematic diagram of the decomposition structure of the electrode kit of the urine electrochemical detection device of the present invention is as follows Figure 1 ;

[0022] Figure 4 This is a schematic diagram of the decomposed structure of Example 2 of the present invention;

[0023] Figure 5 This is a schematic diagram of the decomposition structure of Example 3 of the present invention;

[0024] Figure 6 This is a schematic diagram of the decomposed structure of Example 4 of the present invention;

[0025] Figure 7 The schematic diagram of the decomposition structure of the electrode kit of the urine electrochemical detection device of the present invention is as follows Figure 2 ;

[0026] Figure 8 It is a schematic diagram of the overall structure of an electrode kit for a urine electrochemical detection device of the present invention;

[0027] Fig. 9 It is a schematic diagram of the overall cross-sectional structure of an electrode kit of a urine electrochemical detection device of the present invention;

[0028] Fig.10 This is a schematic diagram of the overall structure of a buffer bottle of a urine electrochemical detection device of the present invention;

[0029] Fig.11 This is a schematic diagram of the exploded structure of a buffer bottle of a urine electrochemical detection device of the present invention;

[0030] Fig.12 It is a schematic diagram of the overall cross-sectional structure of a buffer bottle of a urine electrochemical detection device of the present invention;

[0031] Figure numerals: 1. electrode kit, 11. electrochemical test paper, 111. conductive printed layer, 12. contact plate, 121. via solder pin, 122. gold finger, 123. round hole, 13. leakage hole, 14. cutting head, 15. glass fiber cotton sheet, 16. shell, 161. boss, 17. external thread, 2. buffer bottle, 21. buffer, 22. membrane to be penetrated, 23. detachable cover, 24. bottle body, 25. bottle cap, 26. sealing ring, 27. rubber ring, 28. threaded inner wall. DETAILED DESCRIPTION

[0032] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present invention more clearly understood, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0033] It should be noted that when a component is referred to as being "installed on", "provided on", "covered on", "sleeved on", or "locked on" another component, it can be directly on the other component or indirectly on the other component.

[0034] It should be understood that, in the description of the present invention, “several” means two or more than two, unless otherwise clearly and specifically defined.

[0035] In addition, the orientations or positional relationships indicated by terms such as "inside", "on", "between", "both sides", "one side", "top", "bottom", and "side" are based on the orientations or positional relationships shown in the drawings and are only for the convenience of describing the present invention and simplifying the description. They do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0036] It should be noted that the terms "first", "second", "third", etc. are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, features defined as "first", "second", "third", etc. may explicitly or implicitly include one or more of the features.

[0037] It should be noted that the "and / or" in this article is only a description of the association relationship of the associated objects, indicating that there can be three relationships. For example, A and / or B can represent: A exists alone, A and B exist at the same time, and B exists alone. Among them, A and B can be singular or plural respectively.

[0038] Example 1

[0039] Please refer to Figure 1-Figure 3 and Figure 7-Figure 12 The present invention provides a urine electrochemical detection device, which is connected to an electrochemical workstation or a portable reading instrument, and includes an electrode kit 1 and a buffer bottle 2. The electrode kit 1 can be detachably installed in the buffer bottle 2. The electrode kit 1 is used to quickly collect urine, and the buffer bottle 2 is used to dilute the collected urine and obtain urine with a precise dilution ratio and a precisely controlled pH value to meet the detection requirements; the electrochemical workstation or the portable reading instrument is connected to the urine electrochemical detection device, and can analyze the precise value of a specific component in the urine.

[0040] The electrode kit 1 comprises an electrochemical test paper 11, a contact plate 12 and a leakage hole 13. The electrochemical test paper 11 adopts a screen-printed electrode or an electrode of laser-induced graphene, and the electrode contacts urine to generate a measurable electrical signal (such as current or voltage); the contact plate 12 is a PCB board connecting the electrochemical test paper 11 and the electrochemical workstation, and the material is FR-4, which plays a conductive role; the leakage hole 13 is used for urine collection, and urine is introduced into the electrode kit 1, and urine contacts the electrochemical test paper 11; the leakage hole 13 is arranged on the electrochemical test paper 11. The side of the paper 11, the electrochemical test paper 11 is electrically connected to the contact plate 12, the buffer bottle 2 is provided with a buffer solution 21, the leakage hole 13 can be immersed in the buffer solution 21, when the electrode kit 1 is installed in the buffer solution bottle 2, the buffer solution 21 in the buffer solution bottle 2 enters the electrode kit 1 through the leakage hole 13, the buffer solution 21 is a fixed volume of PBS liquid, and the liquid has been prepared with a pH value as required, so that urine with an accurate dilution ratio and an accurate pH value can be obtained to comply with the detection method using non-enzyme catalysts in biological detection.

[0041] The above structural design solves the problem that there is no convenient urine electrochemical detection device for home detection, and designs a urine electrochemical detection device that is convenient for home detection and easy to operate.

[0042] Furthermore, since the urine electrochemical detection device needs to be connected to an electrochemical workstation or a portable reading instrument to analyze the precise value of a specific component in urine, it is also necessary to design the urine electrochemical detection device to be able to quickly and stably connect to the electrochemical workstation or the portable reading instrument, as follows:

[0043] The electrode kit 1 is provided with a cutting head 14, and the buffer bottle 2 is provided with a membrane to be penetrated 22, and the cutting head 14 can puncture the membrane to be penetrated 22; when urine dilution is required, the cutting head 14 is directly aimed at the membrane to be penetrated 22, and the membrane to be penetrated 22 is punctured, so that the electrode kit 1 can be inserted into the buffer bottle 2, and the leakage hole 13 is immersed in the buffer solution 21. Since the membrane to be penetrated 22 is elastic, the electrode kit 1 can also be well fixed, so that the end of the contact plate 12 can be exposed, and the electrochemical workstation or portable reading instrument can be stably connected to the contact plate 12; in addition, the structural design will not make the opening too large, and can prevent liquid from spilling when the buffer bottle 2 needs to be shaken.

[0044] Furthermore, when the electrochemical test paper 11 uses a laser-induced graphene electrode, if the electrochemical test paper 11 is directly exposed below the leakage hole 13, when the amount of urine is large, the urine will impact the laser-induced graphene electrode, causing the graphene to fall off, thereby reducing the accuracy of the detection. Therefore, the following structure is designed: the electrode kit 1 also includes a glass fiber cotton sheet 15, and the glass fiber cotton sheet 15 is arranged on both sides of the electrochemical test paper 11, and the leakage hole 13 is located on the side of the glass fiber cotton sheet 15; the upper and lower layers of the glass fiber cotton sheet 15 can clamp the electrochemical test paper 11, and have two functions. One is to protect and fix the graphene layer on the fragile laser-induced graphene test paper so that it will not fall off; the other is that when collecting urine, the liquid adsorption of the glass fiber cotton sheet 15 can provide a fixed volume of urine adsorption, providing a dilution standard for the subsequent use of the buffer bottle 2.

[0045] Specifically, the structure of the contact plate 12 is as follows: a via solder pin 121 is provided on one end of the contact plate 12, and the via solder pin 121 pierces and electrically connects to the electrochemical test paper 11; the electrochemical test paper 11 is provided with a conductive printed layer 111, and the via solder pin 121 pierces and electrically connects to the conductive printed layer 111, further ensuring that the electrochemical test paper 11 can be electrically conductive; a gold finger 122 is provided on the other end of the contact plate 12, and the gold finger 122 is connected to an electrochemical workstation or a portable reading instrument.

[0046] Furthermore, the electrode kit 1 includes a shell 16, the leakage hole 13 is arranged on the shell 16, a plurality of bosses 161 are arranged in the shell 16, a circular hole 123 is provided on the contact plate 12, and the boss 161 passes through the circular hole 123. This structural design provides sufficient mechanical force to the contact plate 12.

[0047] Furthermore, the buffer bottle 2 includes a bottle body 24 and a bottle cap 25 , the membrane to be penetrated 22 is fixedly arranged on the bottle cap 25 , a sealing ring 26 is provided between the bottle body 24 and the bottle cap 25 , and the design of the sealing ring 26 enables the buffer 21 to be better sealed in the bottle body 24 .

[0048] The specific steps of using the urine electrochemical detection device of the present invention are as follows:

[0049] S1: When urinating, place the leakage hole 13 on the electrode kit 1 in the urine flow, or immerse the leakage hole 13 on the electrode kit 1 in the urine of the urine collection container for a period of time, wait for the internal glass fiber cotton sheet 15 to fully absorb the urine, and then take out the electrode kit 1. At this time, the volume of urine absorbed by the glass fiber cotton sheet in the kit is L1, and in this process, it is necessary to avoid the gold finger 122 of the end contact plate 12 from contacting the urine;

[0050] S2: Place the electrode kit 1 upright and wait for the excess urine to drip out along the direction of the cutter until the dripping stops;

[0051] S3: Take out the buffer bottle 2, align the cutting head 14 on the electrode kit 1 with the membrane to be penetrated 22 on the buffer bottle 2, and insert it with force to pierce the membrane to be penetrated 22 and insert it into the buffer bottle 2, so that the leakage hole 13 is immersed in the buffer 21;

[0052] S4: Gently shake the buffer bottle 2 upright to fully blend the liquid in the electrode kit 1 with the liquid in the buffer bottle. Be careful not to spill the liquid. Assuming that the volume of the buffer 21 in the buffer bottle is L2, the urine to be tested in the kit in the buffer bottle is finally diluted to L1 / (L1+L2);

[0053] S5: Connect the electrochemical workstation to the gold finger 122 of the contact plate 12 at the end of the electrode reagent kit 1, load the voltage according to the preset program of the electrochemical workstation to start the experiment, so as to analyze the precise value of the specific component in the urine.

[0054] In summary, the urine electrochemical detection device of the present invention is a very convenient tool. Due to its convenient operation, it is suitable for non-professionals to conduct home testing. The device can protect the test paper, control the pH value of urine, and dilute the urine in a precise proportion, making the current new indicator measurement method practical.

[0055] Example 2

[0056] Reference Figure 4 , the difference from Example 1 is that there is no cutting head 14 on the electrode kit 1, the buffer bottle 2 is provided with a removable cover 23, the removable cover 23 can be a pull-out cover or a threaded cover, the inner wall of the buffer bottle 2 is provided with a rubber ring 27, the outer wall of the electrode kit 1 is clamped in the rubber ring 27, and the electrode kit 1 is clamped by the setting of the rubber ring 27; when the urine needs to be diluted, the removable cover 23 of the buffer bottle 2 is opened, the shape of the rubber ring 27 matches the shape of the electrode kit 1, and is a round cake with a rectangular hole in the middle, and the outer wall of the electrode kit 1 is clamped in the rectangular hole.

[0057] Example 3

[0058] Reference Figure 5The difference from Example 1 is that there is no cutting head 14 on the electrode kit 1, and the buffer bottle 2 is provided with a removable cover 23, which can be a pull-out cover or a threaded cover. The outer wall of the electrode kit 1 is provided with a rubber ring 27, and the shape of the rubber ring 27 matches the shape of the electrode kit 1, which is a round cake with a rectangular hole in the middle. The rubber ring 27 on the outer wall of the electrode kit 1 is clamped on the inner wall of the buffer bottle 2, that is, the round cake-shaped structure is installed in the mouth of the buffer bottle 2.

[0059] Example 4

[0060] Reference Figure 6 , which is different from Example 1 in that the buffer bottle 2 is provided with a threaded inner wall 28, and the electrode kit 1 is provided with an external thread 17, and the external thread 17 is threadedly matched with the threaded inner wall 28. The buffer bottle 2 is cylindrical, and the external thread 17 of the electrode kit 1 is provided on a section of a cylinder, and the electrode kit 1 is fixed to the buffer bottle 2 by rotating the thread.

[0061] The above-mentioned embodiments only express several implementation methods of the present invention, and the description thereof is relatively specific and detailed, but it cannot be understood as limiting the scope of the patent of the present invention. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, which all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be subject to the attached claims.

Claims

1. A urine electrochemical detection device, characterized in that: The invention comprises an electrode kit (1) and a buffer bottle (2), wherein the electrode kit (1) can be detachably installed in the buffer bottle (2), the electrode kit (1) comprises an electrochemical test paper (11), a contact plate (12) and a leakage hole (13), wherein the leakage hole (13) is arranged on the side of the electrochemical test paper (11), the electrochemical test paper (11) is electrically connected to the contact plate (12), a buffer solution (21) is arranged in the buffer bottle (2), and the leakage hole (13) can be immersed in the buffer solution (21).

2. The urine electrochemical detection device according to claim 1, characterized in that: The electrode kit (1) is provided with a cutting head (14), the buffer bottle (2) is provided with a membrane to be penetrated (22), and the cutting head (14) can puncture the membrane to be penetrated (22).

3. The urine electrochemical detection device according to claim 1, characterized in that: The buffer bottle (2) is provided with a detachable cover (23), the inner wall of the buffer bottle (2) or the outer wall of the electrode kit (1) is provided with a rubber ring (27), the outer wall of the electrode kit (1) is clamped in the rubber ring (27) or the rubber ring (27) of the outer wall of the electrode kit (1) is clamped on the inner wall of the buffer bottle (2).

4. The urine electrochemical detection device according to claim 1, characterized in that: The buffer bottle (2) is provided with a threaded inner wall (28), and the electrode reagent kit (1) is provided with an external thread (17), and the external thread (17) is threadably matched with the threaded inner wall (28).

5. The urine electrochemical detection device according to claim 1, characterized in that: The electrode kit (1) further comprises glass fiber cotton sheets (15), wherein the glass fiber cotton sheets (15) are arranged on both sides of the electrochemical test paper (11), and the liquid leakage hole (13) is located on the side of the glass fiber cotton sheet (15).

6. The urine electrochemical detection device according to claim 1, characterized in that: A via welding needle (121) is provided on one end of the contact plate (12), and the via welding needle (121) pierces and electrically connects the electrochemical test paper (11).

7. The urine electrochemical detection device according to claim 6, characterized in that: The electrochemical test paper (11) is provided with a conductive printed layer (111), and the via soldering needle (121) pierces and electrically connects the conductive printed layer (111).

8. The urine electrochemical detection device according to claim 6, characterized in that: A gold finger (122) is provided on the other end of the contact plate (12).

9. The urine electrochemical detection device according to claim 2, characterized in that: The buffer bottle (2) comprises a bottle body (24) and a bottle cap (25), the membrane to be penetrated (22) is fixedly arranged on the bottle cap (25), and a sealing ring (26) is arranged between the bottle body (24) and the bottle cap (25).

10. The urine electrochemical detection device according to claim 1, characterized in that: The electrode kit (1) comprises a shell (16), the liquid leakage hole (13) is arranged on the shell (16), a plurality of convex columns (161) are arranged in the shell (16), a circular hole (123) is arranged on the contact plate (12), and the convex column (161) penetrates the circular hole (123).

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