Tablet grinding device for pharmaceutical experiment

Abstract

The tablet grinding device comprises a mounting cylinder, a bottom shell is fixed to the bottom wall of the mounting cylinder, an inner cylinder is arranged in the mounting cylinder in a sliding mode, a reset mechanism is arranged between the inner cylinder and the mounting cylinder, a limiting mechanism is arranged at one end of the inner cylinder, and a plugging cover is arranged on the right wall of the mounting cylinder; and the rotating block is rotationally installed in the inner cylinder, and a cutting mechanism is installed in the rotating block. The cutting mechanism is driven by the arranged first air cylinder to move, the cutting mechanism can cut up tablets placed in the mounting cylinder and preliminarily cut and crush the tablets, so that the subsequent grinding efficiency can be improved, meanwhile, the arranged pushing mechanism pushes the rotating block to move in the direction of the plugging cover until the tablets are completely ground into powder, and the grinding efficiency is improved. And obtained medicine powder enters a collecting box through a filter plate and a discharging opening to be collected, the whole structure of the device is exquisite, and the grinding efficiency is high.

Description

Technical Field

[0001] The invention relates to the technical field of tablet grinding, in particular to a tablet grinding device for pharmaceutical experiments. Background Art

[0002] Pharmaceutical trials usually refer to drug clinical trials, which are systematic studies aimed at discovering or verifying the clinical medicine, pharmacology and other pharmacodynamic effects, adverse reactions, or absorption, distribution, metabolism and excretion of an experimental drug in order to determine the efficacy and safety of the drug. Drug clinical trials are an indispensable part of the new drug development process. They not only help confirm the effectiveness and safety of drugs, but also provide a scientific basis for the further application and optimization of drugs.

[0003] At present, when conducting pharmaceutical experiments in hospital pharmacies, drug preparation rooms, pharmaceutical factories, pharmaceutical companies, drug testing institutes, etc., it is generally necessary to grind the prepared tablets before conducting subsequent experiments. However, the existing tablet grinding devices generally directly extrude and grind the tablets, which is inefficient when processing larger tablets. At the same time, the drug powder in the grinding cylinder is difficult to clean after grinding.

[0004] To this end, the present invention provides a tablet grinding device for pharmaceutical experiments to solve the above problems. Summary of the invention

[0005] In view of the deficiencies in the prior art, the present invention provides a tablet grinding device for pharmaceutical experiments, which solves the problem that the existing tablet grinding devices generally directly extrude and grind the tablets, which is inefficient when processing larger tablets and the drug powder in the grinding cylinder is difficult to clean after grinding.

[0006] To achieve the above objectives, the present invention is implemented through the following technical solutions: A tablet grinding device for pharmaceutical experiments, comprising:

[0007] A mounting tube, wherein a bottom shell is fixed to the bottom wall of the mounting tube, an inner tube is slidably mounted in the mounting tube, a reset mechanism is mounted between the inner tube and the mounting tube, a limiting mechanism is mounted at one end of the inner tube, and a blocking cover is mounted on the right wall of the mounting tube;

[0008] A rotating block, the rotating block is rotatably mounted in the inner cylinder, and a cutting mechanism is installed in the rotating block;

[0009] An L-shaped mounting plate, a first cylinder is fixed to the top of the side wall of the L-shaped mounting plate, a movable end of the first cylinder is rotatably connected to the cutting mechanism, and a driving mechanism for driving the rotating block to rotate is installed on the inner wall of the L-shaped mounting plate;

[0010] A pushing mechanism, the pushing mechanism is installed between the bottom shell and the rotating block;

[0011] The collecting box is slidably inserted on the side wall of the bottom shell, a feeding port is provided on the bottom wall of the mounting cylinder corresponding to the position of the collecting box, and a filter plate is installed on the bottom wall of the inner cylinder corresponding to the position of the collecting box.

[0012] Preferably, two slide grooves are symmetrically provided on the inner wall of the installation cylinder, and the reset mechanism is installed in the slide grooves.

[0013] Preferably, the reset mechanism comprises a sliding shaft, the sliding shaft is fixed between the inner walls of the sliding groove, and a sliding block is slidably mounted on the sliding shaft;

[0014] The slider is slidably installed in the slide groove, one side of the slider is fixed on the side wall of the inner cylinder, and a spring is fixed between the side wall of the slider and the inner wall of the slide groove;

[0015] The spring sleeve is arranged on the outside of the sliding shaft.

[0016] Preferably, a mounting groove is provided on the right wall of the mounting tube, and the blocking cover is screwed into the mounting groove.

[0017] Preferably, the blocking cover comprises a cover plate, a threaded joint is fixed on one side of the cover plate, and a handle is fixed on the other side of the cover plate;

[0018] A grinding disc is fixed on one side of the threaded joint.

[0019] Preferably, the cutting mechanism comprises a connecting shaft, one end of which slides through the rotating block and is rotatably connected to the movable end of the first cylinder, and the other end of the connecting shaft is fixed with a special-shaped cutting head via a mounting frame.

[0020] Preferably, a cavity is provided on the inner wall of the rotating block corresponding to the position of the mounting frame, and a storage groove matching the special-shaped cutting head is provided on the right end of the rotating block.

[0021] Preferably, the driving mechanism comprises a self-locking motor, the self-locking motor is fixed on the side wall of the L-shaped mounting plate, and a driving gear is fixed on the power shaft of the self-locking motor;

[0022] The driving gear is meshingly connected with an outer gear ring;

[0023] The outer gear ring is fixed on the outer wall of the rotating block, and the width of the outer gear ring is greater than the width of the driving gear.

[0024] Preferably, the pushing mechanism comprises a second cylinder, the movable end of which slides through the side wall of the bottom shell and is fixed with a connecting plate;

[0025] A first ring is fixed on the top end of the connecting plate through a connecting rod, and the first ring is fixed on the outer wall of the rotating block.

[0026] Preferably, the limiting mechanism includes a second ring, which is rotatably mounted on the outer wall of the inner cylinder through a bearing, a limiting block is symmetrically fixed on the outer wall of the second ring, a push plate is fixed on one side of the second ring, and a limiting baffle matching the limiting block is fixed on the side wall edge of the mounting cylinder.

[0027] Beneficial Effects

[0028] The present invention provides a tablet grinding device for pharmaceutical experiments. Compared with the prior art, it has the following advantages:

[0029] Beneficial effects:

[0030] (1) The pharmaceutical experiment tablet grinding device drives the cutting mechanism to move by means of a first cylinder. The cutting mechanism can cut the tablets placed in the mounting tube into pieces and perform preliminary cutting and crushing on the tablets, thereby accelerating the subsequent grinding efficiency. At the same time, the driving mechanism drives the rotating block to move toward the sealing cover until the tablets are completely ground into powder. The obtained powder passes through the filter plate and the discharge port into the collecting box for collection. The overall structure of the device is sophisticated and the grinding efficiency is high.

[0031] (2) When the inside of the pharmaceutical experiment tablet grinding device needs to be cleaned after the grinding operation is completed, the push plate is pushed to drive the second ring to rotate until the limit block on the second ring is separated from the limit baffle. At this time, under the action of the spring, the inner cylinder moves a distance to the outside of the mounting cylinder. At this time, the right end of the rotating block is flush with the right end of the inner cylinder, and the discharge port is exposed. At this time, the part of the debris adhering to the right end of the rotating block is cleaned with a brush and discharged through the discharge port, so as to facilitate the cleaning of the inside of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] Figure 1 It is a perspective view of the external left side structure of the present invention;

[0033] Figure 2 It is a perspective view of the external right side structure of the present invention;

[0034] Figure 3 It is a three-dimensional diagram of the structure of the pushing mechanism of the present invention;

[0035] Figure 4 It is a left structural stereogram of the inner cylinder and the mounting cylinder of the present invention in a separated state;

[0036] Figure 5 It is a right side structural stereogram of the inner cylinder and the mounting cylinder of the present invention in a separated state;

[0037] Figure 6 It is a three-dimensional diagram of the half-section structure of the inner cylinder of the present invention;

[0038] Figure 7 It is a three-dimensional cross-section of the rotating block of the present invention.

[0039] In the figure, 1, bottom shell; 2, mounting cylinder; 3, inner cylinder; 4, rotating block; 5, blocking cover; 51, cover plate; 52, threaded joint; 53, grinding disc; 54, handle; 6, cutting mechanism; 61, connecting shaft; 62, mounting frame; 63, special-shaped cutting head; 7, L-shaped mounting plate; 8, first cylinder; 9, driving mechanism; 91, self-locking motor; 92, driving gear; 93, outer gear ring; 10, pushing machine Structure; 101, second cylinder; 102, connecting plate; 103, connecting rod; 104, first ring; 11, collecting box; 12, limiting mechanism; 121, second ring; 122, limiting block; 123, push plate; 13, limiting baffle; 14, slide groove; 15, slide shaft; 16, slider; 17, spring; 18, mounting groove; 19, feed port; 20, filter plate; 21, storage groove; 22, cavity. DETAILED DESCRIPTION

[0040] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0041] Embodiment 1:

[0042] See also Figure 1-2 , a tablet grinding device for pharmaceutical experiments, comprising:

[0043] The installation tube 2 has a bottom shell 1 fixed to the bottom wall thereof, an inner tube 3 is slidably mounted in the installation tube 2, a reset mechanism is mounted between the inner tube 3 and the installation tube 2, a limiting mechanism 12 is mounted at one end of the inner tube 3, and a blocking cover 5 is mounted on the right wall of the installation tube 2;

[0044] A rotating block 4 is rotatably mounted in the inner cylinder 3, and a cutting mechanism 6 is mounted in the rotating block 4;

[0045] An L-shaped mounting plate 7, a first cylinder 8 is fixed to the top of the side wall of the L-shaped mounting plate 7, a movable end of the first cylinder 8 is rotatably connected to the cutting mechanism 6, and a driving mechanism 9 for driving the rotating block 4 to rotate is installed on the inner wall of the L-shaped mounting plate 7;

[0046] A pushing mechanism 10, which is installed between the bottom shell 1 and the rotating block 4;

[0047] The collecting box 11 is slidably inserted on the side wall of the bottom shell 1 , a feeding port 19 is opened at the bottom wall of the mounting cylinder 2 corresponding to the collecting box 11 , and a filter plate 20 is installed at the bottom wall of the inner cylinder 3 corresponding to the collecting box 11 .

[0048] In this embodiment, the cutting mechanism 6 is driven to move by the first cylinder 8, and the cutting mechanism 6 can preliminarily cut and crush the tablets placed in the installation cylinder 2, so as to speed up the subsequent grinding efficiency. The driving mechanism 9 can drive the rotating block 4 to rotate, and the rotating block 4 cooperates with the blocking cover 5 to grind the shredded tablets. At the same time, the driving mechanism 10 is used to push the rotating block 4 to move toward the blocking cover 5 until the tablets are completely ground into powder. The obtained powder passes through the filter plate 20 and the discharge port 19 into the collection box 11 for collection. When placing the tablets, the blocking cover 5 can be opened to put the tablets in, and the blocking cover 5 can be opened to clean the inside of the device after the crushing is completed.

[0049] Embodiment 2:

[0050] See also Figure 3-7 This embodiment provides a technical solution based on the first embodiment:

[0051] Two slide grooves 14 are symmetrically formed on the inner wall of the installation tube 2 , and the reset mechanism is installed in the slide grooves 14 .

[0052] The reset mechanism includes a sliding shaft 15, which is fixed between the inner walls of the sliding groove 14, and a slider 16 is slidably mounted on the sliding shaft 15;

[0053] The slider 16 is slidably installed in the slide groove 14, one side of the slider 16 is fixed on the side wall of the inner tube 3, and a spring 17 is fixed between the side wall of the slider 16 and the inner wall of the slide groove 14;

[0054] The spring 17 is sleeved on the outside of the sliding shaft 15 .

[0055] The limiting mechanism 12 includes a second ring 121, which is rotatably mounted on the outer wall of the inner tube 3 through a bearing. A limiting block 122 is symmetrically fixed to the outer wall of the second ring 121, a push plate 123 is fixed to one side of the second ring 121, and a limiting baffle 13 that cooperates with the limiting block 122 is fixed to the edge of the side wall of the mounting tube 2.

[0056] In this embodiment, in the initial state, the filter plate 20 on the inner cylinder 3 corresponds to the position of the discharge port 19, and the inner cylinder 3 is stuck in the position of the limit baffle 13 through the set limit mechanism 12, and the spring 17 is in a compressed state. When the inside of the device needs to be cleaned after the grinding operation is completed, the push plate 123 is turned to drive the second ring 121 to rotate until the limit block 122 on the second ring 121 is separated from the limit baffle 13. At this time, under the action of the spring 17, the inner cylinder 3 moves a distance to the outside of the installation cylinder 2. At this time, the right end of the rotating block 4 is flush with the right end of the inner cylinder 3, and the discharge port 19 is exposed. At this time, the partial debris adhering to the right end of the rotating block 4 is cleaned by a brush and discharged through the discharge port 19, so as to facilitate the cleaning of the inside of the device.

[0057] A mounting groove 18 is formed on the right wall of the mounting tube 2 , and the blocking cover 5 is screwed into the mounting groove 18 .

[0058] The blocking cover 5 includes a cover plate 51, a threaded joint 52 is fixed to one side of the cover plate 51, and a handle 54 is fixed to the other side of the cover plate 51;

[0059] A grinding disc 53 is fixed to one side of the threaded joint 52 .

[0060] The cutting mechanism 6 includes a connecting shaft 61 , one end of which slides through the rotating block 4 and is rotatably connected to the movable end of the first cylinder 8 , and the other end of the connecting shaft 61 is fixed with a special-shaped cutting head 63 through a mounting frame 62 .

[0061] A cavity 22 is provided on the inner wall of the rotating block 4 at a position corresponding to the mounting bracket 62 , and a storage groove 21 matching the special-shaped cutting head 63 is provided on the right end of the rotating block 4 .

[0062] The driving mechanism 9 includes a self-locking motor 91, which is fixed on the side wall of the L-shaped mounting plate 7, and a driving gear 92 is fixed on the power shaft of the self-locking motor 91;

[0063] The driving gear 92 is meshingly connected with an outer gear ring 93;

[0064] The outer gear ring 93 is fixed on the outer wall of the rotating block 4 , and the width of the outer gear ring 93 is greater than the width of the driving gear 92 .

[0065] The pushing mechanism 10 includes a second cylinder 101, the movable end of the second cylinder 101 slides through the side wall of the bottom shell 1 and is fixed with a connecting plate 102;

[0066] A first ring 104 is fixed to the top of the connecting plate 102 via a connecting rod 103 , and the first ring 104 is fixed to the outer wall of the rotating block 4 .

[0067] In this embodiment, the cutting mechanism 6 is capable of shredding the tablets placed in the mounting tube 2, thereby facilitating the subsequent grinding operation of the rotating block 4 in cooperation with the blocking cover 5. When grinding the tablets, first open the blocking cover 5, place the tablets in the gap between the rotating block 4 and the mounting tube 2, and then screw the blocking cover 5 onto the mounting groove 18. The first cylinder 8 is controlled to extend, and the first cylinder 8 pushes the special-shaped cutting head 63 out of the storage groove 21 through the connecting shaft 61 and the mounting frame 62. The special-shaped cutting head 63 shreds the tablets in cooperation with the side wall of the blocking cover 5 during the movement, and then the first cylinder 8 is controlled to reset. When the special-shaped cutting head 63 is stored in the storage groove 21, the side wall of the rotating block 4 can scrape off the tablet debris adhering to the special-shaped cutting head 63 until the special-shaped cutting head 63 is completely stored in the storage groove 21 (at this time, the right end of the special-shaped cutting head 63 is aligned with the rotating block 4). The right wall of the movable block 4 is flush, and the right end of the rotating block 4 is a plane at this time), and then the switch of the self-locking motor 91 is turned on. The self-locking motor 91 drives the rotating block 4 to rotate through the driving gear 92 and the outer gear ring 93. During the rotation of the rotating block 4, the grinding disc 53 on the blocking cover 5 is used to grind the tablets. At the same time, the rotating block 4 is driven by the set pushing mechanism 10 to move toward the blocking cover 5 until the tablet grinding operation is completed. The obtained powder enters the collection box 11 through the filter plate 20 and the discharge port 19 for collection.

[0068] Meanwhile, the contents not described in detail in this specification belong to the prior art known to those skilled in the art.

Claims

1. A tablet grinding device for pharmaceutical experiments, characterized in that: include: A mounting tube (2), wherein a bottom shell (1) is fixed to the bottom wall of the mounting tube (2), an inner tube (3) is slidably mounted in the mounting tube (2), a reset mechanism is mounted between the inner tube (3) and the mounting tube (2), a limiting mechanism (12) is mounted at one end of the inner tube (3), and a blocking cover (5) is mounted on the right wall of the mounting tube (2); a rotating block (4), the rotating block (4) being rotatably mounted in the inner cylinder (3), and a cutting mechanism (6) being mounted in the rotating block (4); An L-shaped mounting plate (7), a first cylinder (8) being fixed on the top of the side wall of the L-shaped mounting plate (7), a movable end of the first cylinder (8) being rotatably connected to the cutting mechanism (6), and a driving mechanism (9) for driving the rotating block (4) to rotate being installed on the inner wall of the L-shaped mounting plate (7); A pushing mechanism (10), wherein the pushing mechanism (10) is installed between the bottom shell (1) and the rotating block (4); A collecting box (11) is slidably inserted on the side wall of the bottom shell (1), a discharge port (19) is provided on the bottom wall of the mounting cylinder (2) at a position corresponding to the collecting box (11), and a filter plate (20) is installed on the bottom wall of the inner cylinder (3) at a position corresponding to the collecting box (11).

2. A tablet grinding device for pharmaceutical experiments according to claim 1, characterized in that: Two slide grooves (14) are symmetrically formed on the inner wall of the installation cylinder (2), and the reset mechanism is installed in the slide grooves (14).

3. A tablet grinding device for pharmaceutical experiments according to claim 2, characterized in that: The reset mechanism comprises a sliding shaft (15), the sliding shaft (15) is fixed between the inner walls of the sliding groove (14), and a sliding block (16) is slidably mounted on the sliding shaft (15); The slider (16) is slidably mounted in the slide groove (14), one side of the slider (16) is fixed on the side wall of the inner cylinder (3), and a spring (17) is fixed between the side wall of the slider (16) and the inner wall of the slide groove (14); The spring (17) is sleeved on the outside of the sliding shaft (15).

4. A tablet grinding device for pharmaceutical experiments according to claim 1, characterized in that: The right wall of the installation tube (2) is provided with an installation groove (18), and the blocking cover (5) is screwed into the installation groove (18).

5. A tablet grinding device for pharmaceutical experiments according to claim 4, characterized in that: The blocking cover (5) comprises a cover plate (51), a threaded joint (52) is fixed on one side of the cover plate (51), and a handle (54) is fixed on the other side of the cover plate (51); A grinding disc (53) is fixed to one side of the threaded joint (52).

6. The tablet grinding device for pharmaceutical experiments according to claim 1, characterized in that: The cutting mechanism (6) comprises a connecting shaft (61), one end of which slides through the rotating block (4) and is rotatably connected to the movable end of the first cylinder (8), and the other end of the connecting shaft (61) is fixed with a special-shaped cutting head (63) via a mounting frame (62).

7. A tablet grinding device for pharmaceutical experiments according to claim 6, characterized in that: A cavity (22) is provided on the inner wall of the rotating block (4) at a position corresponding to the mounting frame (62), and a storage groove (21) matching the special-shaped cutting head (63) is provided on the right end of the rotating block (4).

8. The tablet grinding device for pharmaceutical experiments according to claim 1, characterized in that: The driving mechanism (9) comprises a self-locking motor (91), the self-locking motor (91) is fixed on the side wall of the L-shaped mounting plate (7), and a driving gear (92) is fixed on the power shaft of the self-locking motor (91); The driving gear (92) is meshingly connected with an outer gear ring (93); The outer gear ring (93) is fixed on the outer wall of the rotating block (4), and the width of the outer gear ring (93) is greater than the width of the driving gear (92).

9. The tablet grinding device for pharmaceutical experiments according to claim 1, characterized in that: The pushing mechanism (10) comprises a second cylinder (101), the movable end of the second cylinder (101) slidingly passes through the side wall of the bottom shell (1) and is fixed with a connecting plate (102); A first collar (104) is fixed to the top end of the connecting plate (102) via a connecting rod (103), and the first collar (104) is fixed to the outer wall of the rotating block (4).

10. The tablet grinding device for pharmaceutical experiments according to claim 1, characterized in that: The limiting mechanism (12) comprises a second sleeve (121), the second sleeve (121) being rotatably mounted on the outer wall of the inner cylinder (3) via a bearing, a limiting block (122) being symmetrically fixed to the outer wall of the second sleeve (121), a push plate (123) being fixed to one side of the second sleeve (121), and a limiting baffle (13) matching with the limiting block (122) being fixed to the side wall edge of the mounting cylinder (2).

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